carbachol has been researched along with inositol in 149 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (46.98) | 18.7374 |
| 1990's | 73 (48.99) | 18.2507 |
| 2000's | 5 (3.36) | 29.6817 |
| 2010's | 1 (0.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bryan, J; Slaby, F | 1 |
| Nakagawa-Yagi, Y; Nakamura, H; Saito, Y; Takada, Y | 1 |
| Bloch-Faure, M; Chabardès, D; Guillon, G; Meneton, P; Morel, F; Rajerison, RM | 1 |
| Claro, E; Fain, JN; Wallace, MA | 1 |
| Laitinen, JT; Saavedra, JM; Vakkuri, O | 1 |
| Chen, CK; Johnston, MV; Silverstein, FS | 1 |
| Chung, HC; Fleming, N | 1 |
| Baraban, JM; Murphy, TH; Wright, DD | 1 |
| Crews, FT; Madamba, S; Pontzer, NJ; Siggins, GR | 1 |
| Guiramand, J; Recasens, M; Sassetti, I; Vignes, M | 1 |
| Crook, RB; Lui, GM; Polansky, JR; Song, MK; Tong, LP; Yabu, JM | 1 |
| Katz, A; Simon, MI; Wu, D | 1 |
| Malaisse, WJ; Ramirez, R; Sener, A | 1 |
| Hall, IP | 1 |
| Kowatch, MA; Roth, GS | 1 |
| Kimura, H; Miyamoto, A; Ohshika, H | 1 |
| Dawson, G; Mangoura, D | 1 |
| Keith, RA; Moore, WC; Patel, J; Salama, AI | 1 |
| Limatola, C; Luly, P; Pacini, L; Spinedi, A | 1 |
| Bonner, MJ; Tilson, HA | 1 |
| Buxton, IL; Zhang, LB | 1 |
| Bockaert, J; Manzoni, OJ; Prezeau, L | 1 |
| Beaujouan, JC; Dietl, M; Glowinski, J; Torrens, Y | 1 |
| Azim, S; Baron, CB; Pompeo, JN | 1 |
| Iriuchijima, T; Michimata, T; Mizuma, H; Mori, M; Murakami, M; Yamada, M | 1 |
| de la Llosa, P; Roy, M; Tertrin-Clary, C | 1 |
| Gruber, MG; Lebrun, CJ; Meister, M; Unger, T | 1 |
| Challiss, RA; Lambert, DG; Nahorski, SR | 1 |
| Natsuki, R | 1 |
| Field, JB; Taguchi, M | 1 |
| Kopp, R; Mayer, P; Pfeiffer, A | 1 |
| Hartmann, T; Kahan, C; Pouyssegur, J; Seuwen, K | 1 |
| Abe, MT; Nakahata, N; Nakanishi, H | 1 |
| Cooke, AM; Nahorski, SR; Potter, BV; Wojcikiewicz, RJ | 1 |
| Horwitz, J | 1 |
| Shuttleworth, TJ | 1 |
| Bartolami, S; Guiramand, J; Lenoir, M; Mayat, E; Pujol, R; Récasens, M; Rumigny, JF | 1 |
| Dartt, DA; Dicker, DM; Hodges, RR; Kjeldsen, IM; Murphy, SA; Ronco, LV | 1 |
| Houlihan, MJ; Powers, RE; Saluja, AK; Steer, ML | 1 |
| Brown, JH; Brunton, LL; Buxton, IL | 1 |
| Murphy, S; Welk, G | 1 |
| Godfrey, PP; Grahame-Smith, DG; McClue, SJ; White, AM; Wood, AJ | 1 |
| Harry, GJ; Tandon, P; Tilson, HA | 1 |
| Fujiwara, M; Kameyama, M; Ninomiya, H; Taniguchi, T | 1 |
| Ali, SF; Bonner, M; Tandon, P; Tilson, HA | 1 |
| Benuck, M; Lajtha, A; Reith, ME | 1 |
| Logan, SD; McDermott, EE | 1 |
| Barnes, PJ; Chilvers, ER; Nahorski, SR | 1 |
| Kimura, K; Taniguchi, N; Ukai, Y; Yamazaki, A | 1 |
| Johnson, BG; Schoepp, DD | 1 |
| Gil, DW; Wolfe, BB | 1 |
| Rasmussen, H; Zawalich, KC; Zawalich, WS | 1 |
| Godfrey, PP | 1 |
| Court, JA; Keith, AB; Perry, EK; Smith, CJ | 1 |
| Logan, SD; Stephens, LR | 1 |
| Casebolt, TL; Johnson, GV; Jope, RS | 1 |
| McLeod, JK; Smith, AI; White, LB; Woodcock, EA | 1 |
| Clark, MG; McLeod, JK; Smith, AI; Woodcock, EA | 1 |
| Chaudhry, A; Laychock, SG; Rubin, RP | 1 |
| Gurpide, E; Weiss, DJ | 1 |
| Bowen, WD; Kirschner, BN; Newman, AH; Rice, KC | 1 |
| Crawford, ML; Young, JM | 1 |
| Garg, LC; Kapturczak, E; McArdle, S | 1 |
| Chiba, T; Raffoul, K; Yamada, T | 1 |
| Janowsky, A; Labarca, R; Paul, SM | 3 |
| Fowler, CJ; Ogren, SO; Thorell, G | 1 |
| Baron, CB; Coburn, RF; Pring, M | 1 |
| Biden, TJ; Peter-Riesch, B; Schlegel, W; Wollheim, CB | 1 |
| Brown, JH; Masters, SB; Quinn, MT | 1 |
| Schoepp, DD | 1 |
| Cambray-Deakin, M; Grimble, J; Morrow, C; Murphy, S; Pearce, B | 1 |
| Daly, JW; Hollingsworth, EB | 1 |
| Morrow, C; Murphy, S; Pearce, B | 2 |
| Best, L; Malaisse, WJ; Mathias, PC | 1 |
| Gjörstrup, P; Hjalmarson, A; Jacobsson, B; Ransnäs, L; Sjögren, CG | 1 |
| Rasmussen, H; Takuwa, N; Takuwa, Y | 1 |
| Dumont, JE; Erneux, C; Graff, I; Laurent, E; Mockel, J | 1 |
| Agranoff, BW; Fisher, SK; Heacock, AM | 1 |
| Balduini, W; Costa, LG; Murphy, SD | 1 |
| Kendall, DA; Nahorski, SR | 1 |
| Dandona, P; Jeremy, J; Morrow, C; Murphy, S; Pearce, B | 1 |
| Best, L; Tomlinson, S; Tuersley, MD | 1 |
| de Belleroche, J; Reed, LJ | 1 |
| Biden, TJ; Wollheim, CB | 1 |
| Björklund, PE; Candy, JM; Court, JA; Fowler, CJ; Tiger, G | 1 |
| Downes, CP; Stone, MA | 1 |
| Kendall, DA; Lazareno, S; Nahorski, SR | 1 |
| Batty, I; Nahorski, SR | 1 |
| Agranoff, BW; Schacht, J | 1 |
| Brenning, R | 1 |
| Roufogalis, BD; Sekar, MC | 2 |
| Best, L; Malaisse, WJ | 1 |
| Crews, FT; Gonzales, RA | 1 |
| Nadler, E; Nijjar, MS; Oron, Y | 1 |
| Dibner, MD; Downes, CP; Hanley, MR | 1 |
| Abdel-Latif, AA; Akhtar, RA | 1 |
| Roberts, ML; Tennes, KA | 2 |
| Lupu, M; Oron, Y | 1 |
| Downes, CP; Wusteman, MM | 1 |
| Downes, CP; Irvine, RF; Lander, DJ; Letcher, AJ | 1 |
| Janowsky, A; Labarca, R; Patel, J; Paul, SM | 1 |
| Brown, JH; Brown, SL | 1 |
| Itoi, K; Lebrun, CJ; Steckelings, U; Unger, T; Wende, P | 1 |
| Dreux, C; Lods, JS; Morisset, J; Rossignol, B | 1 |
| Essington, TE; Williams, JA; Yule, DI | 1 |
| Melvin, JE; Zhang, GH | 1 |
| Martin, TV; Weiss, RM; Wheeler, MA | 1 |
| Depoortere, I; Peeters, TL | 1 |
| Brave, SR; Gibson, A; McFadzean, I; Mirzazadeh, S; Tucker, JF; Wayman, C | 1 |
| Ho, XP; Lu, BF; Lu, YM; Wang, WJ; Yan, TH; Yan, YL | 1 |
| Erwin, VG; Radcliffe, RA | 1 |
| Bevilacqua, JA; Downes, CP; Lowenstein, PR | 1 |
| Atack, JR; Fletcher, SR; McKernan, R; Prior, AM; Quirk, K; Ragan, CI | 1 |
| Neuman, RS; Rahman, S | 1 |
| McLaren, J; Ogawa, K; Schacht, J | 1 |
| Ogawa, K; Schacht, J | 1 |
| Ikeda, M | 1 |
| Atack, JR; Griffith, D; Prior, AM; Ragan, CI | 1 |
| Claro, E; Fain, JN; Picatoste, F | 1 |
| McDonald, JM; Sambandam, V; Sekar, MC | 1 |
| Dulchinos, VF; Mundy, WR; Tilson, HA; Ward, TR | 1 |
| Challiss, RA; Jenkinson, S; Nahorski, SR; Patel, N | 1 |
| Laychock, SG; Xia, M | 1 |
| Feldman, EL; Greene, DA; Kato, K; Lien, M; Nakamura, J; Stevens, MJ; Thomas, TP | 1 |
| Downes, CP; Sillence, DJ | 1 |
| Agranoff, BW; Stubbs, EB | 1 |
| Chandler, LJ; Crews, FT; Kurian, P; Narang, N | 1 |
| Bollo, MI; Garrido, MN; Machado-Domenech, EE | 1 |
| Avellino, C; Battaini, F; Fortuna, S; Lorenzini, P; Malvezzi Campeggi, L; Pascale, A; Pintor, A; Salvati, S | 1 |
| Duarte, EP; Oliveira, CR; Rego, AC | 1 |
| Lenox, RH; Watson, DG | 1 |
| Hersey, K; Hu, ZY; Rhodes, PG; Sun, GY; Zhang, JP | 1 |
| Kendall, DA; Marsden, CA; Roberts, RE | 1 |
| Batty, IH; Currie, RA; Downes, CP | 1 |
| del Río, E; Downes, CP; Nicholls, DG; Shinomura, T; van der Kaay, J | 1 |
| Boje, KM; Lakhman, SS | 1 |
| Harbon, S; Lajat, S; Tanfin, Z | 1 |
| Hara, T; Iwanaga, S; Makita, T; Shibata, O; Shibata, S; Sumikawa, K; Tsuda, A | 1 |
| Baron, CB; Broome, R; Coburn, RF; Sul, D | 1 |
| Brandish, PE; Hill, LA; Scolnick, EM; Zheng, W | 1 |
| Matsui, M; Philbrick, W; Sterpka, J; Taketo, MM; Tesz, GJ; Zawalich, KC; Zawalich, WS | 1 |
| Philbrick, W; Yamazaki, H; Zawalich, KC; Zawalich, WS | 1 |
| Zawalich, KC; Zawalich, WS | 1 |
1 trial(s) available for carbachol and inositol
| Article | Year |
|---|---|
[Enantaldehydes and furaldehydes in molimina crurum nocturna including "restless legs". A comparative trial with carbacholine, inositolnicotinate, and placebo].
Topics: Aged; Aldehydes; Carbachol; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Female; Furaldehyde; Humans; Inositol; Leg; Male; Middle Aged; Nicotinic Acids; Paresthesia; Phantom Limb; Placebos; Posture; Pregnancy | 1969 |
148 other study(ies) available for carbachol and inositol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
High uptake of myo-inositol by rat pancreatic tissue in vitro stimulates secretion.
Topics: Amylases; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol; Kinetics; Male; Pancreas; Rats | 1976 |
Suppressive effect of carbachol on forskolin-stimulated neurite outgrowth in human neuroblastoma NB-OK1 cells.
Topics: Atropine; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Colforsin; Cyclic AMP; Drug Interactions; Egtazic Acid; Gallic Acid; Humans; Inositol; Inositol Phosphates; Kinetics; Neurites; Neuroblastoma; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1992 |
Cholinergic stimulation of phosphoinositide metabolism in isolated rat glomeruli.
Topics: Animals; Carbachol; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol; Inositol Phosphates; Kidney Glomerulus; Lithium; Male; Mathematics; Parasympathomimetics; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1992 |
Concerted CMP-dependent [3H]inositol labeling of phosphoinositides and agonist activation of phospholipase C in rat brain cortical membranes.
Topics: Animals; Carbachol; Cell Membrane; Cerebral Cortex; Cytidine Monophosphate; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Phosphatidylinositols; Rats; Tritium; Type C Phospholipases | 1992 |
Pineal muscarinic phosphoinositide responses: age-associated sensitization, agonist-induced desensitization and increase in melatonin release from cultured pineal glands.
Topics: Aging; Animals; Carbachol; Culture Techniques; Inositol; Kinetics; Male; Melatonin; Phosphatidylinositols; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Signal Transduction | 1992 |
N-methyl-D-aspartate-mediated injury enhances quisqualic acid-stimulated phosphoinositide turnover in perinatal rats.
Topics: Amino Acids; Animals; Animals, Newborn; Calcium; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; Hydrolysis; Inositol; Microinjections; N-Methylaspartate; Pharmaceutical Vehicles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1992 |
Arachidonic acid regulates the phosphoinositide signal transduction pathway in submandibular acinar cells.
Topics: Animals; Arachidonic Acid; Carbachol; Cells, Cultured; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Leukotrienes; Male; Mucins; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Prostaglandins; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Submandibular Gland | 1992 |
Phosphoinositide turnover associated with synaptic transmission.
Topics: Animals; Atropine; Calcium; Carbachol; Cerebral Cortex; Diglycerides; Inositol; Organ Culture Techniques; Phosphatidylinositols; Picrotoxin; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Tritium | 1992 |
Concentrations of carbachol stimulating phosphoinositide hydrolysis cause a sustained decrease in membrane potential and firing rate: role of inositol and inositol polyphosphate second messengers.
Topics: Action Potentials; Animals; Carbachol; Hydrolysis; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Membrane Potentials; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Second Messenger Systems | 1992 |
Dithiotreitol specifically inhibits metabotropic responses of glutamate and depolarizing agents in rat brain synaptoneurosomes.
Topics: Animals; Antioxidants; Calcium; Carbachol; Dithiothreitol; Fura-2; Glutamates; Glutamic Acid; Inositol; Inositol Phosphates; Kinetics; Membrane Potentials; Potassium; Prosencephalon; Rats; Spectrometry, Fluorescence; Synaptosomes | 1992 |
Stimulation of inositol phosphate formation in cultured human retinal pigment epithelium.
Topics: Angiotensin II; Arginine Vasopressin; Bombesin; Bradykinin; Carbachol; Cells, Cultured; Epoprostenol; Histamine; Humans; Inositol; Inositol Phosphates; Kinetics; Norepinephrine; Parasympathomimetics; Pigment Epithelium of Eye; Protease Inhibitors; Serotonin; Substance P; Thrombin; Vasopressins | 1992 |
Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C.
Topics: Adenylate Cyclase Toxin; Animals; Carbachol; Cell Line; Cytosol; DNA; Enzyme Activation; GTP-Binding Proteins; Inositol; Inositol Phosphates; Isoenzymes; Kinetics; Macromolecular Substances; Pertussis Toxin; Signal Transduction; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 1992 |
A sensitive radioisotopic assay of myo-inositol: its application to rat pancreatic islets.
Topics: Animals; Carbachol; Carbon Radioisotopes; Glucose; Glutamates; Glycolysis; In Vitro Techniques; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Ketoglutaric Acids; Kinetics; Lens, Crystalline; Organ Specificity; Parotid Gland; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains | 1992 |
Agonist-induced inositol phosphate responses in bovine airway submucosal glands.
Topics: Animals; Bradykinin; Carbachol; Cattle; Histamine; In Vitro Techniques; Inositol; Inositol Phosphates; Interleukin-1; Kinetics; Muscle, Smooth; Norepinephrine; Pyrilamine; Sodium Fluoride; Trachea; Tritium | 1992 |
Alpha 1-adrenergic and muscarinic-cholinergic stimulated inositol trisphosphate production may proceed through different post-receptor signal transduction pathways in parotid acini.
Topics: Animals; Carbachol; Epinephrine; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Parotid Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Signal Transduction | 1991 |
Interaction between PAF and drugs that stimulate formation of inositol phosphates.
Topics: Animals; Calcium; Carbachol; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Norepinephrine; Parotid Gland; Phospholipid Ethers; Platelet Activating Factor; Potassium; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1991 |
Chronic opioid treatment attenuates carbachol-mediated polyphosphoinositide hydrolysis in chick embryo neuronal cultures.
Topics: Analgesics; Animals; Bradykinin; Brain; Carbachol; Cells, Cultured; Chick Embryo; Endorphins; Enkephalin, Leucine-2-Alanine; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Neurons; Phosphatidylinositol Phosphates; Phosphatidylinositols; Receptors, Opioid | 1991 |
Role of calcium in regulation of phosphoinositide signaling pathway.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Carbachol; Cations, Divalent; Cells, Cultured; Cerebral Cortex; Diltiazem; Egtazic Acid; Inositol; Inositol Phosphates; Isradipine; Kinetics; Models, Neurological; Neurons; Oxadiazoles; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Signal Transduction; Sulfonamides; Verapamil | 1991 |
Phosphoinositide turnover in human neuroblastoma cells (SK-N-BE).
Topics: Atropine; Carbachol; Cell Line; Humans; Inositol; Inositol Phosphates; Kinetics; Neuroblastoma; Phosphatidylinositols | 1991 |
Compensatory alterations in receptor-stimulated phosphoinositide hydrolysis in the hippocampus vary as a function of dose of colchicine.
Topics: Animals; Carbachol; Colchicine; Dose-Response Relationship, Drug; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol; Male; N-Methylaspartate; Norepinephrine; Phosphatidylinositols; Pyramidal Tracts; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Reference Values | 1991 |
Muscarinic receptors in canine colonic circular smooth muscle. II. Signal transduction pathways.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Carbachol; Chromatography, High Pressure Liquid; Colon; Cyclic AMP; Dogs; Female; GTP-Binding Proteins; Hydrolysis; Inositol; Inositol Phosphates; Male; Muscle, Smooth; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Muscarinic; Signal Transduction; Time Factors; Tritium | 1991 |
beta-N-methylamino-L-alanine is a low-affinity agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Diamino; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cyanobacteria Toxins; Cycloleucine; Dizocilpine Maleate; Embryo, Mammalian; Glutamates; Inositol; Inositol Phosphates; Kinetics; Mice; Neurons; Neurotoxins; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Inhibitory effects of substance P and carbachol on the saturable sodium-dependent uptake process of myo-inositol in rat parotid gland.
Topics: Animals; Calcium; Carbachol; Cytochalasin B; Glucose; In Vitro Techniques; Inositol; Male; Parotid Gland; Phloretin; Phospholipids; Rats; Rats, Inbred Strains; Sodium; Substance P; Temperature | 1991 |
Inositol 1,4,5-trisphosphate compartmentalization in tracheal smooth muscle.
Topics: Animals; Atropine; Carbachol; Chromatography, High Pressure Liquid; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Models, Biological; Muscle Contraction; Muscle, Smooth; Swine; Trachea; Tritium | 1992 |
Hypothyroidism inhibits the formation of inositol phosphate in response to carbachol in the striatum of adult rat.
Topics: Animals; Atropine; Binding Sites; Carbachol; Cell Membrane; Cerebral Cortex; Corpus Striatum; Hippocampus; Hypothyroidism; Inositol; Inositol Phosphates; Male; Parasympatholytics; Quinuclidinyl Benzilate; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Comparison of inositol phosphates accumulation induced by different effectors in rat thyroid slices.
Topics: Animals; Carbachol; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Rats; Sodium Fluoride; Thyroid Gland; Thyrotropin; Vanadates | 1991 |
Central vasopressin pretreatment sensitizes phosphoinositol hydrolysis in the rat septum.
Topics: Animals; Arginine Vasopressin; Brain; Carbachol; Cerebral Ventricles; In Vitro Techniques; Injections, Intraventricular; Inositol; Inositol Phosphates; Kinetics; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Reference Values; Tritium | 1990 |
Accumulation and metabolism of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 in muscarinic-receptor-stimulated SH-SY5Y neuroblastoma cells.
Topics: Animals; Carbachol; Cell Line; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Mice; Neuroblastoma; Receptors, Muscarinic | 1991 |
Effect of ethanol on calcium-uptake and phospholipid turnover by stimulation of adrenoceptors and muscarinic receptors in mouse brain and heart synaptosomes.
Topics: Animals; Brain; Calcium; Carbachol; Choline; Ethanol; Heart; Inositol; Intracellular Membranes; Isoproterenol; Male; Mice; Myocardium; Norepinephrine; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Receptors, Adrenergic; Receptors, Muscarinic; Synaptosomes | 1991 |
Phosphoinositides metabolism in primary culture of dog thyroid cells: effects of thyrotropin and carbachol.
Topics: Animals; Bucladesine; Carbachol; Cells, Cultured; Dogs; Inositol; Inositol Phosphates; Kinetics; Phosphatidylinositols; Radioisotope Dilution Technique; Thyroid Gland; Thyrotropin; Tritium | 1990 |
Agonist-induced desensitization of cholinergically stimulated phosphoinositide breakdown is independent of endogenously activated protein kinase C in HT-29 human colon carcinoma cells.
Topics: Carbachol; Colonic Neoplasms; Enzyme Activation; GTP-Binding Proteins; Humans; Hydrolysis; Inositol; Ionomycin; N-Methylscopolamine; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Sodium Fluoride; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1990 |
Strong and persistent activation of inositol lipid breakdown induces early mitogenic events but not Go to S phase progression in hamster fibroblasts. Comparison of thrombin and carbachol action in cells expressing M1 muscarinic acetylcholine receptors.
Topics: Adenylate Cyclase Toxin; Animals; Atropine; Calcium; Carbachol; Cell Cycle; Cell Line; Clone Cells; Cricetinae; Cricetulus; DNA Replication; Fibroblasts; Inositol; Inositol Phosphates; Kinetics; Lung; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pirenzepine; Proto-Oncogenes; Receptors, Muscarinic; Resting Phase, Cell Cycle; S Phase; Thrombin; Transfection; Virulence Factors, Bordetella | 1990 |
PGJ2 and delta 12PGJ2 inhibit cell growth accompanied with inhibition of phosphoinositide turnover in human astrocytoma cells.
Topics: Astrocytoma; Carbachol; Cell Division; Cyclic AMP; DNA; GTP-Binding Proteins; Histamine; Humans; Inositol; Isoproterenol; Kinetics; Phosphatidylinositols; Prostaglandin D2; Tumor Cells, Cultured | 1990 |
Inhibition of inositol 1,4,5-trisphosphate metabolism in permeabilised SH-SY5Y human neuroblastoma cells by a phosphorothioate-containing analogue of inositol 1,4,5-trisphosphate.
Topics: Animals; Carbachol; Cell Line; Cell Membrane; Cell Membrane Permeability; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroblastoma; Organothiophosphorus Compounds | 1990 |
Carbachol and bradykinin increase the production of diacylglycerol from sources other than inositol-containing phospholipids in PC12 cells.
Topics: Bradykinin; Calcium; Carbachol; Diglycerides; Glycerides; Inositol; Inositol Phosphates; N-Methylscopolamine; Osmolar Concentration; Parasympathomimetics; Pertussis Toxin; Pheochromocytoma; Phospholipids; Scopolamine Derivatives; Triglycerides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Receptor-activated calcium entry in exocrine cells does not occur via agonist-sensitive intracellular pools.
Topics: Animals; Calcium; Carbachol; Ducks; Inositol; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Models, Biological; Nasal Cavity; Organothiophosphorus Compounds; Receptors, Muscarinic; Salt Gland | 1990 |
A M3 muscarinic receptor coupled to inositol phosphate formation in the rat cochlea?
Topics: Animals; Carbachol; Cells, Cultured; Cochlea; Inositol; Inositol Phosphates; Lithium; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tritium | 1990 |
Lacrimal gland inositol trisphosphate isomer and inositol tetrakisphosphate production.
Topics: Animals; Calcium; Carbachol; Chromatography, High Pressure Liquid; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isomerism; Kinetics; Lacrimal Apparatus; Male; Rats; Rats, Inbred Strains; Signal Transduction | 1990 |
Inositol trisphosphate production and amylase secretion in mouse pancreatic acini.
Topics: Amylases; Animals; Carbachol; Ceruletide; Dose-Response Relationship, Drug; Female; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Mice; Pancreas; Sugar Phosphates | 1985 |
Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes.
Topics: Animals; Calcimycin; Calcium; Carbachol; Chlorides; Heart; Hydrolysis; Inositol; Inositol Phosphates; Ion Channels; Kinetics; Lithium; Lithium Chloride; Male; Myocardium; Norepinephrine; Phosphatidylinositols; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1985 |
Arachidonic acid evokes inositol phospholipid hydrolysis in astrocytes.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Astrocytes; Carbachol; Cells, Cultured; Cerebral Cortex; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Norepinephrine; Platelet Activating Factor; Rats | 1989 |
Subacute and chronic in vivo lithium treatment inhibits agonist- and sodium fluoride-stimulated inositol phosphate production in rat cortex.
Topics: Animals; Carbachol; Cell Membrane; Cerebral Cortex; Chlorides; Cyclic AMP; Inositol; Inositol Phosphates; Isoproterenol; Kinetics; Lithium; Lithium Chloride; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Sodium Fluoride; Sugar Phosphates; Type C Phospholipases | 1989 |
Colchicine-induced alterations in receptor-stimulated phosphoinositide hydrolysis in the rat hippocampus.
Topics: Animals; Carbachol; Colchicine; Hippocampus; Hydrolysis; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Phosphatidylinositols; Rats; Rats, Inbred F344; Receptors, Muscarinic; Reference Values | 1989 |
Effects of oxygen depletion on norepinephrine- and carbachol-stimulated phosphoinositide turnover in rat brain slices.
Topics: Animals; Brain; Carbachol; Hypoxia; In Vitro Techniques; Inositol; Inositol Phosphates; Norepinephrine; Oxygen; Phosphatidylinositols; Phospholipids; Rats; Tissue Distribution | 1989 |
Characterization of receptor-coupled phosphoinositide hydrolysis in the rat hippocampus after intradentate colchicine.
Topics: Animals; Carbachol; Caudate Nucleus; Cerebral Cortex; Choline O-Acetyltransferase; Colchicine; Hippocampus; Hydrolysis; In Vitro Techniques; Infusions, Parenteral; Inositol; Kinetics; Male; Norepinephrine; Phosphatidylinositols; Quinuclidinyl Benzilate; Rats; Rats, Inbred F344; Receptors, Muscarinic; Serotonin | 1989 |
Phosphoinositide hydrolysis induced by depolarization and sodium channel activation in mouse cerebrocortical slices.
Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Carbachol; Cations, Divalent; Cerebral Cortex; Hydrolysis; In Vitro Techniques; Inositol; Magnesium; Male; Mice; Mice, Inbred BALB C; Monensin; Neuromuscular Depolarizing Agents; Phosphatidylinositols; Potassium; Sodium; Sodium Channels; Tetrodotoxin | 1989 |
Inhibition of agonist-stimulated inositol lipid metabolism by the anticonvulsant carbamazepine in rat hippocampus.
Topics: Animals; Carbachol; Carbamazepine; Hippocampus; Histamine; In Vitro Techniques; Inositol; Lipid Metabolism; Male; Phenytoin; Rats; Rats, Inbred Strains; Sodium Channels; Tetrodotoxin; Veratrine | 1989 |
Characterization of agonist-stimulated incorporation of myo-[3H]inositol into inositol phospholipids and [3H]inositol phosphate formation in tracheal smooth muscle.
Topics: Animals; Bradykinin; Carbachol; Cattle; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Inositol; Inositol Phosphates; Muscle, Smooth; Phosphatidylinositols; Stimulation, Chemical; Time Factors; Trachea; Tritium | 1989 |
Enhancement of phosphatidylinositol turnover and cyclic nucleotide accumulation by chronic anethole trithione treatment in rat submaxillary glands.
Topics: Anethole Trithione; Animals; Anisoles; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Inositol; Isoflurophate; Male; Phosphatidylinositols; Pilocarpine; Rats; Rats, Inbred Strains; Submandibular Gland; Type C Phospholipases | 1989 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the neonatal rat hippocampus by 2-amino-3-phosphonopropionate.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Carbachol; Chlorides; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Inositol; Kainic Acid; Kinetics; Lithium; Lithium Chloride; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains | 1989 |
Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Atropine; Benzodiazepinones; Brain; Carbachol; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Myocardium; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1985 |
Cholinergic agonists prime the beta-cell to glucose stimulation.
Topics: Animals; Arginine; Atropine; Carbachol; Drug Synergism; Glucose; In Vitro Techniques; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Rats; Rats, Inbred Strains; Tolbutamide | 1989 |
Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol.
Topics: Animals; Carbachol; Cerebral Cortex; Cytidine Diphosphate Diglycerides; In Vitro Techniques; Inositol; Lithium; Male; Nucleoside Diphosphate Sugars; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1989 |
Increases in muscarinic stimulated hydrolysis of inositol phospholipids in rat hippocampus following cholinergic deafferentation are not parallelled by alterations in cholinergic receptor density.
Topics: Animals; Carbachol; Cholinergic Fibers; Hippocampus; Inositol; Male; Nicotine; Phospholipids; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1989 |
Formation of [3H]inositol metabolites in rat hippocampal formation slices prelabelled with [3H]inositol and stimulated with carbachol.
Topics: Animals; Carbachol; Chromatography, High Pressure Liquid; Hippocampus; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Rats; Tritium | 1989 |
Modulation of carbachol-stimulated inositol phospholipid hydrolysis in rat cerebral cortex.
Topics: Animals; Carbachol; Cell Membrane; Cerebral Cortex; Chlorides; Guanosine Triphosphate; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Male; Phosphatidylinositols; Rats; Sugar Phosphates; Tritium | 1987 |
Stimulation of phosphatidylinositol metabolism in the isolated, perfused rat heart.
Topics: Animals; Atropine; Bucladesine; Calcium; Carbachol; Chlorides; Heart Atria; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Lithium Chloride; Male; Mast Cells; Myocardium; Norepinephrine; Perfusion; Phosphatidylinositols; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1987 |
Study of receptor-stimulated phosphatidylinositol hydrolysis in intact, perfused rat hearts.
Topics: Animals; Carbachol; Chromatography, High Pressure Liquid; In Vitro Techniques; Inositol; Inositol Phosphates; Myocardium; Norepinephrine; Perfusion; Phosphatidylinositols; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1987 |
The effects of fatty acids on phosphoinositide synthesis and myo-inositol accumulation in exocrine pancreas.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carbachol; Chlorides; Fatty Acids; Inositol; Inositol Phosphates; Lithium; Lithium Chloride; Male; Pancreas; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1987 |
Regulation of phosphoinositide hydrolysis in transformed human endometrial cells.
Topics: Acetylcholine; Adenocarcinoma; Atropine; Carbachol; Cell Differentiation; Chlorides; Endometrium; Female; Humans; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Phorbol Esters; Phosphatidylinositols; Receptors, Muscarinic; Tamoxifen; Tumor Cells, Cultured; Uterine Neoplasms | 1988 |
Sigma receptors negatively modulate agonist-stimulated phosphoinositide metabolism in rat brain.
Topics: Animals; Brain; Carbachol; In Vitro Techniques; Inositol; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Synaptosomes | 1988 |
GABAB receptor-mediated inhibition of histamine H1-receptor-induced inositol phosphate formation in slices of rat cerebral cortex.
Topics: Animals; Baclofen; Carbachol; Cerebral Cortex; gamma-Aminobutyric Acid; Histamine; Inositol; Inositol Phosphates; Isonicotinic Acids; Kinetics; Lithium; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Histamine H1; Sugar Phosphates | 1988 |
Effects of osmolality on phosphoinositide hydrolysis in renal medulla.
Topics: Animals; Carbachol; Inositol; Kidney Medulla; Male; Mannitol; Membrane Lipids; Osmolar Concentration; Phosphatidylinositols; Rabbits; Sodium Chloride; Urea | 1988 |
Divergent stimulatory and inhibitory actions of carbamoylcholine on gastric D-cells.
Topics: Animals; Carbachol; Cells, Cultured; Cyclic AMP; Dogs; Gastric Fundus; Gastric Mucosa; Inositol; Inositol Phosphates; Pertussis Toxin; Phosphatidylinositols; Somatostatin; Virulence Factors, Bordetella | 1987 |
Neurotransmitter-stimulated inositol phosphate accumulation in hippocampal slices.
Topics: Animals; Carbachol; Hippocampus; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Manganese; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Phorbol Esters; Radioisotope Dilution Technique; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tritium | 1987 |
Investigation into the effects in-vitro of the 5-hydroxytryptamine reuptake inhibitor, alaproclate, on carbachol-stimulated inositol phospholipid breakdown in the rat cerebral cortex.
Topics: Alanine; Animals; Antidepressive Agents; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Rats; Rats, Inbred Strains; Sugar Phosphates | 1987 |
Inositol lipid turnover and compartmentation in canine trachealis smooth muscle.
Topics: Animals; Carbachol; Dogs; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Muscle, Smooth; Phosphatidylinositols; Phospholipids; Sugar Phosphates; Trachea; Tritium | 1989 |
Ca2+-mediated generation of inositol 1,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate in pancreatic islets. Studies with K+, glucose, and carbamylcholine.
Topics: Animals; Calcium; Carbachol; Glucose; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Islets of Langerhans; Kinetics; Male; Potassium; Rats; Rats, Inbred Strains; Sugar Phosphates; Tritium | 1987 |
Agonist-induced desensitization of muscarinic receptor-mediated calcium efflux without concomitant desensitization of phosphoinositide hydrolysis.
Topics: Astrocytoma; Calcium; Carbachol; Cell Line; Chromatography, Ion Exchange; Humans; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; N-Methylscopolamine; Phosphatidylinositols; Receptors, Muscarinic; Scopolamine Derivatives; Time Factors | 1985 |
Manganese stimulates the incorporation of [3H]inositol into a pool of phosphatidylinositol in brain that is not coupled to agonist-induced hydrolysis.
Topics: Animals; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol; Kinetics; Male; Manganese; Norepinephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Tritium | 1985 |
Activation of muscarinic and of alpha 1-adrenergic receptors on astrocytes results in the accumulation of inositol phosphates.
Topics: Animals; Astrocytes; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Inositol; Inositol Phosphates; Kinetics; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Sugar Phosphates; Tritium; Yohimbine | 1985 |
Manganese stimulates incorporation of [3H]inositol into an agonist-insensitive pool of phosphatidylinositol in brain membranes.
Topics: Animals; Carbachol; Cell Membrane; Cytidine Diphosphate Diglycerides; Hippocampus; Inositol; Male; Manganese; Phosphatidylinositols; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1985 |
Accumulation of inositol phosphates and cyclic AMP in guinea-pig cerebral cortical preparations. Effects of norepinephrine, histamine, carbamylcholine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Histamine; Inositol; Inositol Phosphates; Kinetics; Male; Metiamide; Norepinephrine; Prazosin; Propranolol; Pyrilamine; Serotonin; Sugar Phosphates; Tritium | 1985 |
Astrocytes have both M1 and M2 muscarinic receptor subtypes.
Topics: Animals; Astrocytes; Atropine; Benzodiazepinones; Carbachol; Cyclic AMP; Inositol; Isoproterenol; Phospholipids; Pirenzepine; Propranolol; Rats; Receptors, Muscarinic | 1986 |
Receptor-mediated inositol phospholipid hydrolysis in astrocytes.
Topics: Animals; Astrocytes; Calcimycin; Calcium; Carbachol; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Hydrolysis; Inositol; Inositol Phosphates; Lithium; Membrane Lipids; Norepinephrine; Phosphatidylinositols; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Time Factors | 1986 |
Stimulation by glucose and carbamylcholine of phospholipase C in pancreatic islets.
Topics: Animals; Atropine; Calcium; Carbachol; Gliclazide; Glucose; In Vitro Techniques; Inositol; Islets of Langerhans; Phosphatidylinositols; Potassium; Rats; Rats, Inbred Strains; Tritium; Type C Phospholipases; Verapamil | 1985 |
Muscarinic receptors in mammalian myocardium: effects of atrial and ventricular receptors on phosphatidylinositol metabolism and adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Atrial Function; Carbachol; Cats; Cyclic AMP; Heart; Inositol; Kinetics; Myocardium; Oxotremorine; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Muscarinic; Ventricular Function | 1986 |
Carbachol induces a rapid and sustained hydrolysis of polyphosphoinositide in bovine tracheal smooth muscle measurements of the mass of polyphosphoinositides, 1,2-diacylglycerol, and phosphatidic acid.
Topics: Animals; Carbachol; Cattle; Diglycerides; Glycerides; Hydrolysis; Inositol; Kinetics; Muscle, Smooth; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphatidylinositols; Trachea; Tritium | 1986 |
Carbachol and sodium fluoride, but not TSH, stimulate the generation of inositol phosphates in the dog thyroid.
Topics: Animals; Atropine; Carbachol; Chlorides; Dogs; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Phorbol 12,13-Dibutyrate; Phorbol Esters; Sodium Fluoride; Sugar Phosphates; Thyroid Gland; Thyrotropin; Tritium | 1987 |
Enhanced coupling of neonatal muscarinic receptors in rat brain to phosphoinositide turnover.
Topics: Aging; Animals; Animals, Newborn; Carbachol; Cerebral Cortex; Inositol; Phosphatidylinositols; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1987 |
Developmental changes in muscarinic receptor-stimulated phosphoinositide metabolism in rat brain.
Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebral Cortex; Inositol; Mathematics; Phosphatidylinositols; Phospholipids; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic | 1987 |
Acute and chronic lithium treatments influence agonist and depolarization-stimulated inositol phospholipid hydrolysis in rat cerebral cortex.
Topics: Animals; Carbachol; Cerebral Cortex; Histamine; Hydrolysis; Inositol; Lithium; Male; Norepinephrine; Phosphatidylinositols; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Inositol phospholipids are probably not the source of arachidonic acid for eicosanoid synthesis in astrocytes.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Astrocytes; Calcimycin; Carbachol; Cells, Cultured; Cerebral Cortex; Eicosanoic Acids; Inositol; Inositol Phosphates; Kinetics; Norepinephrine; Phosphatidylinositols; Quinacrine; Rats; Sugar Phosphates | 1987 |
Inositol uptake and metabolism in molluscan neuronal tissue.
Topics: Animals; Biological Transport; Carbachol; Cell Membrane; Electric Stimulation; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lymnaea; Membrane Lipids; Neurons; Sodium; Type C Phospholipases | 1988 |
Increased polyphosphoinositide responsiveness in the cerebral cortex induced by cholinergic denervation.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; Cerebral Cortex; Denervation; Inositol; Inositol Phosphates; Kinetics; Male; Rats; Receptors, Muscarinic; Substantia Innominata; Sugar Phosphates | 1988 |
Active transport of myo-inositol in rat pancreatic islets.
Topics: Animals; Biological Transport, Active; Carbachol; Cations, Monovalent; Cytochalasin B; Hexoses; In Vitro Techniques; Inositol; Islets of Langerhans; Male; Phlorhizin; Rats; Rats, Inbred Strains | 1986 |
Stimulation of inositol phospholipid breakdown in rat cortical and hippocampal miniprisms by noradrenaline, 5-hydroxytryptamine and carbachol: some methodological aspects.
Topics: Animals; Carbachol; Cerebral Cortex; Freezing; Hippocampus; In Vitro Techniques; Inositol; Male; Norepinephrine; Phospholipids; Potassium; Rats; Rats, Inbred Strains; Serotonin; Tissue Preservation | 1987 |
Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland.
Topics: Animals; Carbachol; In Vitro Techniques; Inositol; Intracellular Fluid; Lithium; Parotid Gland; Phosphatidylinositols; Rats; Receptors, Muscarinic; Stimulation, Chemical | 1986 |
Pirenzepine indicates heterogeneity of muscarinic receptors linked to cerebral inositol phospholipid metabolism.
Topics: Animals; Atropine; Benzodiazepinones; Brain; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol; Inositol Phosphates; Medulla Oblongata; Pirenzepine; Pons; Rats; Receptors, Muscarinic; Stimulation, Chemical | 1985 |
Differential effects of lithium on muscarinic receptor stimulation of inositol phosphates in rat cerebral cortex slices.
Topics: Animals; Carbachol; Carbon Radioisotopes; Cerebral Cortex; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Lithium; Male; Rats; Receptors, Muscarinic; Sugar Phosphates; Tritium | 1985 |
Stimulation of hydrolysis of phosphatidic acid by cholinergic agents in guinea pig synaptosomes.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Carbachol; Cerebral Cortex; Dinitrophenols; Drug Synergism; Glucose; Glycerol; Guinea Pigs; Hydrolysis; Inositol; Parasympathomimetics; Phosphates; Phosphatidylinositols; Phospholipids; Phosphorus Radioisotopes; Synaptosomes; Tritium | 1974 |
Differential effects of phenylmethanesulfonyl fluoride (PMSF) on carbachol and potassium stimulated phosphoinositide turnover and contraction in longitudinal smooth muscle of guinea pig ileum.
Topics: Animals; Carbachol; Female; Guinea Pigs; Ileum; Inositol; Kinetics; Muscle Contraction; Muscle, Smooth; Phenylmethylsulfonyl Fluoride; Phosphatidylinositols; Potassium; Sulfones; Tritium | 1984 |
Nutrient and hormone-neurotransmitter stimuli induce hydrolysis of polyphosphoinositides in rat pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Carbachol; Cholecystokinin; Glucose; Inositol; Islets of Langerhans; Kinetics; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorus Radioisotopes; Rats; Tritium | 1984 |
Characterization of neurotransmitter receptor-mediated phosphatidylinositol hydrolysis in the rat hippocampus.
Topics: Animals; Carbachol; Hippocampus; Hydrolysis; Inositol; Inositol Phosphates; Male; Norepinephrine; Phentolamine; Phenylephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Time Factors | 1984 |
Muscarinic-receptor stimulation enhances polyphosphoinositide breakdown in guinea-pig ileum smooth muscle.
Topics: Animals; Atropine; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Inositol; Lithium; Muscle, Smooth; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Receptors, Muscarinic; Stimulation, Chemical | 1984 |
Characterization of the cholinergic stimulation of phosphoinositide hydrolysis in rat brain slices.
Topics: Acetylcholine; Animals; Brain; Carbachol; Inositol; Inositol Phosphates; Male; Phosphatidylinositols; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1984 |
Phosphoinositide breakdown in isolated rat parotid membranes. Stimulation by cholinergic and alpha-adrenergic agonists.
Topics: Animals; Atropine; Buffers; Carbachol; Cell Membrane; Cytosol; Epinephrine; Inositol; Osmolar Concentration; Parotid Gland; Phosphatidylinositols; Propranolol; Rats | 1984 |
Sympathetic denervation impairs agonist-stimulated phosphatidylinositol metabolism in rat parotid glands.
Topics: Animals; Carbachol; Diglycerides; In Vitro Techniques; Inositol; Male; Parotid Gland; Phenylephrine; Phosphates; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Stimulation, Chemical; Substance P; Sympathectomy | 1983 |
Requirement for calcium ions in acetylcholine-stimulated phosphodiesteratic cleavage of phosphatidyl-myo-inositol 4,5-bisphosphate in rabbit iris smooth muscle.
Topics: Acetylcholine; Animals; Calcimycin; Calcium; Carbachol; Female; Hydrolysis; In Vitro Techniques; Inositol; Iris; Male; Microsomes; Muscle, Smooth; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rabbits | 1980 |
Agonist-stimulated breakdown of myo-[2-3H] inositol-labelled phosphatidylinositol in mouse pancreas.
Topics: Animals; Appetite Depressants; Calcium; Carbachol; Cell Membrane; Cholecystokinin; Cytosol; Hydrolysis; Inositol; Male; Mice; Pancreas; Peptide Fragments; Phosphatidylinositols; Sincalide; Stimulation, Chemical; Tritium | 1981 |
Neurotransmitter-caused increase in [3H]inositol incorporation into phosphatidylinositol de novo synthesis vs exchange.
Topics: Animals; Atropine; Carbachol; Epinephrine; Inositol; Parotid Gland; Phentolamine; Phosphates; Phosphatidylinositols; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1983 |
Breakdown of polyphosphoinositides and not phosphatidylinositol accounts for muscarinic agonist-stimulated inositol phospholipid metabolism in rat parotid glands.
Topics: 2,4-Dinitrophenol; Animals; Carbachol; Dinitrophenols; Hydrolysis; In Vitro Techniques; Inositol; Inositol Phosphates; Lipid Metabolism; Parotid Gland; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Stimulation, Chemical; Time Factors; Type C Phospholipases | 1983 |
Inositol trisphosphates in carbachol-stimulated rat parotid glands.
Topics: Animals; Carbachol; Chromatography, Ion Exchange; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Parotid Gland; Phosphates; Rats; Stimulation, Chemical; Sugar Alcohols; Sugar Phosphates | 1984 |
The contribution of inositol exchange to agonist-stimulated breakdown of myo- [2-3H] inositol-labelled phosphatidylinositol in mouse exocrine pancreas.
Topics: Animals; Carbachol; In Vitro Techniques; Inositol; Lithium; Mice; Pancreas; Phosphatidylinositols | 1984 |
Phorbol esters inhibit agonist-induced [3H] inositol-1-phosphate accumulation in rat hippocampal slices.
Topics: Animals; Caenorhabditis elegans Proteins; Carbachol; Carcinogens; Carrier Proteins; Hippocampus; Inositol; Inositol Phosphates; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1984 |
Muscarinic stimulation of phosphatidylinositol metabolism in atria.
Topics: Animals; Atropine; Calcium; Carbachol; Heart Atria; Hydrolysis; In Vitro Techniques; Inositol; Male; Mice; Myocardium; Parasympathomimetics; Phosphatidylinositols; Tubocurarine | 1983 |
Effects of tachykinins on phosphoinositide metabolism in the hypothalamus: is the NK1 receptor involved?
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Hypothalamus; In Vitro Techniques; Inositol; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; Tachykinins | 1993 |
Phosphoinositide synthesis in desensitized rat pancreatic acinar cells.
Topics: Animals; Carbachol; Ceruletide; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol; Kinetics; Male; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tritium | 1995 |
Pilocarpine and carbachol exhibit markedly different patterns of Ca2+ signaling in rat pancreatic acinar cells.
Topics: Amylases; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Pancreas; Phosphatidylinositols; Pilocarpine; Rats; Rats, Sprague-Dawley; Signal Transduction; Sincalide | 1993 |
Membrane potential regulates Ca2+ uptake and inositol phosphate generation in rat sublingual mucous acini.
Topics: Animals; Biological Transport; Calcium; Carbachol; Feedback; Inositol; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Ion Channels; Male; Manganese; Membrane Potentials; Nifedipine; Rats; Receptors, Muscarinic; Sublingual Gland; Terpenes; Thapsigargin | 1993 |
Effect of carbachol and norepinephrine on phosphatidyl inositol hydrolysis and cyclic AMP levels in guinea pig urinary tract.
Topics: Animals; Carbachol; Colforsin; Cyclic AMP; Guinea Pigs; Hydrolysis; Inositol; Male; Muscle, Smooth; Norepinephrine; Phosphatidylinositols; Ureter; Urethra; Urinary Bladder | 1995 |
Transduction mechanism of motilin and motilides in rabbit duodenal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Carbachol; Duodenum; Erythromycin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol; Inositol Phosphates; Motilin; Muscle, Smooth; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Signal Transduction; Tritium | 1995 |
Nitrergic stimulation does not inhibit carbachol-induced inositol phosphate generation in the rat anococcygeus.
Topics: Anal Canal; Animals; Atropine; Carbachol; Cyclic GMP; Electric Stimulation; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Muscle, Smooth; Nitroprusside; Rats; Rats, Wistar | 1994 |
Alterations of G-protein coupling function in phosphoinositide signalling pathways of rat hippocampus by ischaemic brain injury.
Topics: Aluminum Compounds; Animals; Carbachol; Electroencephalography; Fluorides; Glutamates; Glutamic Acid; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Inositol; Inositol Phosphates; Ischemic Attack, Transient; Male; Norepinephrine; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Reperfusion; Signal Transduction | 1993 |
Characterization of neurotensin-stimulated phosphoinositide hydrolysis in brain regions of long sleep and short sleep mice.
Topics: Animals; Brain; Calcium; Carbachol; Cerebellum; Dose-Response Relationship, Drug; Hippocampus; Histamine H1 Antagonists; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Membrane Lipids; Mesencephalon; Mice; Mice, Inbred Strains; Neurotensin; Nucleus Accumbens; Organ Specificity; Phosphatidylinositols; Phospholipids; Piperidines; Receptors, Neurotensin; Second Messenger Systems; Sleep | 1993 |
Visualization of agonist-stimulated inositol phospholipid turnover in individual neurons of the rat cerebral cortex and hippocampus.
Topics: Animals; Autoradiography; Carbachol; Cerebral Cortex; Cycloleucine; Cytidine Monophosphate; Female; Glycerophospholipids; Hippocampus; In Vitro Techniques; Inositol; Lithium; Neurons; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Wistar; Stimulation, Chemical | 1994 |
Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers.
Topics: Animals; Carbachol; Cell Membrane Permeability; Cerebral Cortex; CHO Cells; Cricetinae; Cytidine; Cytidine Monophosphate; Diphosphonates; Glycerophospholipids; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Male; Phosphatidic Acids; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Prodrugs; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Tritium | 1994 |
Myo-inositol reduces serotonin (5-HT2) receptor induced homologous and heterologous desensitization.
Topics: Animals; Carbachol; In Vitro Techniques; Inositol; Motor Cortex; N-Methylaspartate; Neurons; Phenylephrine; Rats; Receptors, Adrenergic, alpha-1; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Somatosensory Cortex | 1993 |
Effect of aging on myo-inositol and phosphoinositide metabolism in the cochlear and vestibular sensory epithelia of the rat.
Topics: Adenosine Triphosphate; Aging; Animals; Binding Sites; Carbachol; Cochlea; Epithelium; Hydrolysis; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Phosphatidylinositols; Rats; Rats, Inbred F344; Second Messenger Systems; Vestibule, Labyrinth | 1994 |
Receptor-mediated release of inositol phosphates in the cochlear and vestibular sensory epithelia of the rat.
Topics: Adenosine Triphosphate; Animals; Atropine; Carbachol; Cochlea; Epithelium; Hydrolysis; Inositol; Inositol Phosphates; Male; Potassium; Rats; Rats, Inbred F344; Receptors, Cholinergic; Receptors, Purinergic; Second Messenger Systems; Vestibule, Labyrinth | 1993 |
Reduction of phosphoinositide hydrolysis by L-amino-3-phosphonopropionate may be caused by the inhibition of synthesis of phosphatidylinositols.
Topics: Alanine; Animals; Atropine; Carbachol; Cycloleucine; Depression, Chemical; Hippocampus; Hydrolysis; In Vitro Techniques; Inositol; Lithium Chloride; Male; Phosphatidylinositols; Rats; Rats, Wistar | 1993 |
Characterization of the effects of lithium on phosphatidylinositol (PI) cycle activity in human muscarinic m1 receptor-transfected CHO cells.
Topics: Animals; Carbachol; CHO Cells; Cricetinae; Cytidine Monophosphate; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Phosphatidylinositols; Radioligand Assay; Receptors, Muscarinic; Second Messenger Systems; Transfection | 1993 |
Noradrenaline stimulation unbalances the phosphoinositide cycle in rat cerebral cortical slices.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Cerebral Cortex; Cytidine Diphosphate Diglycerides; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Norepinephrine; Nucleotidyltransferases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Tritium | 1993 |
Bombesin and muscarinic receptor activation in rat pancreas generate cyclic inositol monophosphate: possible involvement of different phospholipase C isoenzymes.
Topics: Animals; Bombesin; Carbachol; Cyclic IMP; Enzyme Activation; In Vitro Techniques; Inositol; Isoenzymes; Kinetics; Neurokinin B; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Bombesin; Receptors, Muscarinic; Receptors, Neurotransmitter; Type C Phospholipases; Zinc | 1993 |
Effect of repeated organophosphate administration on carbachol-stimulated phosphoinositide hydrolysis in the rat brain.
Topics: Animals; Brain; Carbachol; Disulfoton; Down-Regulation; Drug Tolerance; Inositol; Isoflurophate; Male; Phosphatidylinositols; Rats; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Comparative effects of lithium on the phosphoinositide cycle in rat cerebral cortex, hippocampus, and striatum.
Topics: Animals; Carbachol; Cerebral Cortex; Corpus Striatum; Cytidine Monophosphate; Hippocampus; Inositol; Inositol Phosphates; Lithium; Male; Osmolar Concentration; Phosphatidic Acids; Phosphatidylinositols; Rats | 1993 |
Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets.
Topics: Animals; Arginine; Biological Transport; Carbachol; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Hyperglycemia; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Tritium | 1993 |
Ambient glucose and aldose reductase-induced myo-inositol depletion modulate basal and carbachol-stimulated inositol phospholipid metabolism and diacylglycerol accumulation in human retinal pigment epithelial cells in culture.
Topics: Aldehyde Reductase; Carbachol; CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase; Cells, Cultured; Diglycerides; Enzyme Induction; Glucose; Humans; In Vitro Techniques; Inositol; Membrane Proteins; Phosphatidylinositols; Pigment Epithelium of Eye; Sorbitol; Transferases (Other Substituted Phosphate Groups) | 1993 |
Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells.
Topics: Astrocytoma; Carbachol; Humans; Inositol; Lithium; Phosphatidylinositols; Propranolol; Tumor Cells, Cultured | 1993 |
Lithium enhances muscarinic receptor-stimulated CDP-diacylglycerol formation in inositol-depleted SK-N-SH neuroblastoma cells.
Topics: Atropine; Carbachol; Cytidine Diphosphate Diglycerides; Humans; Inositol; Kinetics; Lithium; Neuroblastoma; Receptors, Muscarinic; Tumor Cells, Cultured | 1993 |
Radio-label and mass determinations of inositol 1,3,4,5-tetrakisphosphate formation in rat cerebral cortical slices: differential effects of myo-inositol.
Topics: Animals; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Lithium; Male; Rats; Rats, Sprague-Dawley; Tritium | 1993 |
Carbachol stimulates inositol phosphate formation transiently in Trypanosoma cruzi.
Topics: Animals; Atropine; Carbachol; Inositol; Inositol Phosphates; Time Factors; Trypanosoma cruzi | 1996 |
Influences of hypothyroidism on lipid composition and inositol lipid-linked receptors responsiveness and protein kinase C (PKC) activity in the cerebral cortex of Lewis rats.
Topics: Animals; Carbachol; Cerebral Cortex; Cycloleucine; Hypothyroidism; Inositol; Inositol Phosphates; Male; Neurotoxins; Pirenzepine; Protein Kinase C; Rats; Rats, Inbred Lew; Receptors, Metabotropic Glutamate; Receptors, Muscarinic | 1996 |
Oxidative stress in acidic conditions increases the production of inositol phosphates in chick retinal cells in culture.
Topics: Animals; Ascorbic Acid; Calcium; Carbachol; Cells, Cultured; Chick Embryo; Ferrous Compounds; Glutamic Acid; Hydrogen-Ion Concentration; Inositol; Inositol Phosphates; Kinetics; Lithium; Muscarine; Oxidative Stress; Potassium; Retina; Tritium | 1996 |
Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation.
Topics: Animals; Carbachol; Cell Division; Cells, Cultured; Down-Regulation; Hippocampus; Inositol; Intracellular Signaling Peptides and Proteins; Lithium; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Protein Kinase C; Proteins; Receptors, Muscarinic | 1996 |
In utero hypoxic ischemia decreases the cholinergic agonist-stimulated poly-phosphoinositide turnover in the developing rat brain.
Topics: Animals; Brain; Carbachol; Constriction; Female; Hypoxia; Inositol; Ischemia; Lithium Chloride; Parasympathomimetics; Phosphatidylinositol Phosphates; Pregnancy; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Chloride; Tritium; Uterus | 1995 |
Studies of inositol phosphate export from neuronal tissue in vitro.
Topics: Animals; Carbachol; Cerebral Cortex; Hippocampus; Humans; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Neuroblastoma; Neurons; Rats; Rats, Wistar; Sodium; Tumor Cells, Cultured | 1997 |
Evidence for a model of integrated inositol phospholipid pools implies an essential role for lipid transport in the maintenance of receptor-mediated phospholipase C activity in 1321N1 cells.
Topics: Astrocytoma; Carbachol; Cell Compartmentation; Cell Membrane Permeability; Cytosol; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol; Kinetics; Models, Biological; Phosphatidylinositol Phosphates; Phosphatidylinositols; Receptors, Muscarinic; Tumor Cells, Cultured; Type C Phospholipases | 1998 |
Disruption by lithium of phosphoinositide signalling in cerebellar granule cells in primary culture.
Topics: Animals; Carbachol; Cells, Cultured; Cerebellum; Diglycerides; Extracellular Space; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Muscarinic Agonists; Neurons; Phosphatidylinositols; Potassium Chloride; Rats; Signal Transduction | 1998 |
Chronic dosing with 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, modulates NMDA inhibition of muscarinic-coupled PI hydrolysis in rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; In Vitro Techniques; Inositol; Kynurenic Acid; Male; Muscarinic Agonists; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Carbachol-induced desensitization of PLC-beta pathway in rat myometrium: downregulation of Gqalpha/G11alpha.
Topics: Aluminum Compounds; Animals; Atropine; Carbachol; Enzyme Inhibitors; Female; Fluorides; GTP-Binding Proteins; In Vitro Techniques; Indoles; Inositol; Inositol Phosphates; Isoenzymes; Kinetics; Membrane Potentials; Myometrium; N-Methylscopolamine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phospholipase C beta; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 1998 |
Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs.
Topics: Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dimethylphenylpiperazinium Iodide; Edrophonium; Glucose; Inositol; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neostigmine; Neuromuscular Blocking Agents; Nicotinic Agonists; Organ Preservation Solutions; Phosphatidylinositols; Piperidines; Pyridostigmine Bromide; Radiopharmaceuticals; Rats; Rats, Wistar; Tetrodotoxin; Trachea; Tritium; Tromethamine | 1998 |
Smooth muscle length-dependent PI(4,5)P2 synthesis and paxillin tyrosine phosphorylation.
Topics: Animals; Carbachol; Cholinergic Agonists; Cytoskeletal Proteins; Immunoblotting; In Vitro Techniques; Inositol; Integrin beta1; Muscle, Smooth; Paxillin; Phosphatidylinositol 4,5-Diphosphate; Phosphoproteins; Phosphorylation; Signal Transduction; Swine; Trachea | 2001 |
Scintillation proximity assay of inositol phosphates in cell extracts: high-throughput measurement of G-protein-coupled receptor activation.
Topics: Animals; Atropine; Carbachol; Cell Extracts; Cell Line; CHO Cells; Chromatography, Ion Exchange; Cricetinae; GTP-Binding Proteins; Humans; Inositol; Inositol Phosphates; Lithium Chloride; Muscarinic Antagonists; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Scintillation Counting; Silicates; Tritium; Yttrium; Yttrium Radioisotopes | 2003 |
Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses.
Topics: Animals; Carbachol; Enzyme Activation; Female; Glucose; Heterozygote; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Muscarinic M3; Type C Phospholipases | 2004 |
Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine.
Topics: Animals; Atropine; Carbachol; Colforsin; Diazoxide; Enzyme Activation; Glucose; Hyperglycemia; In Vitro Techniques; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 2006 |
Enhanced activation of phospholipase C and insulin secretion from islets incubated in fatty acid-free bovine serum albumin.
Topics: Animals; Carbachol; Cholinergic Agonists; Diazoxide; Enzyme Activation; In Vitro Techniques; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Potassium Chloride; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2008 |