Page last updated: 2024-08-17

carbachol and darifenacin

carbachol has been researched along with darifenacin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (65.00)29.6817
2010's6 (30.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Bartuschat, A; Fischer, O; Fromm, MF; Gmeiner, P; Heinrich, MR; Hofmann, J; Hübner, H; Kaindl, J; Pratsch, G; Rampp, H; Taudte, RV1
Chapple, CR; Chess-Williams, R; Yamanishi, T; Yasuda, K1
Honda, K; Ikeda, K; Kobayashi, S; Miyata, K; Suzuki, M; Takeuchi, M; Yamada, T1
Iwashita, H; Masunaga, K; Miyamae, K; Murakami, S; Ohtani, M; Ueda, S; Yoshida, M1
Ikeda, K; Kobayashi, S; Miyata, K1
Hein, P; Michel, MC; Michel-Reher, MB; Schneider, T1
Braverman, AS; Ruggieri, MR; Tibb, AS1
Braverman, AS; Doumanian, LR; Ruggieri, MR1
Braverman, AS; Ruggieri, MR1
Braverman, AS; Lebed, B; Linder, M; Ruggieri, MR1
Chapple, CR; Chess-Williams, R; Stevens, LA1
Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H1
Chugh, A; Gupta, JB; Hegde, LG; Kumar, N; Meru, AV; Naruganahalli, KS; Ray, A; Sinha, S1
Finney, SM; Gillespie, JI; Stewart, LH1
Braverman, AS; Khayyam, U; Miller, LS; Ruggieri, MR; Tallarida, RJ; Tiwana, MI; Vegesna, AK1
Li, YR; Matsunami, H1
Haynes, JM; Matsui, M; Short, JL; Ventura, S; White, CW1
Chess-Williams, R; Moro, C; Uchiyama, J1
Arrighi, N; Bodei, S; Cosciani Cunico, S; Michel, MC; Sigala, S; Simeone, C; Spano, P; Zani, D1
Cheng, L; Koon, CM; Lam, WP; Lau, CB; Leung, PC; Liang, W; Tang, HC; Zhou, X1

Other Studies

20 other study(ies) available for carbachol and darifenacin

ArticleYear
Regiospecific Introduction of Halogens on the 2-Aminobiphenyl Subunit Leading to Highly Potent and Selective M3 Muscarinic Acetylcholine Receptor Antagonists and Weak Inverse Agonists.
    Journal of medicinal chemistry, 2020, 04-23, Volume: 63, Issue:8

    Topics: Aminobiphenyl Compounds; Animals; Caco-2 Cells; Drug Inverse Agonism; Halogens; HEK293 Cells; Humans; Male; Molecular Docking Simulation; Muscarinic Agonists; Muscarinic Antagonists; Protein Binding; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3

2020
The role of M(2)-muscarinic receptors in mediating contraction of the pig urinary bladder in vitro.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Animals; Benzofurans; Binding, Competitive; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Membranes; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pyrrolidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Tritium; Urinary Bladder

2000
M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:2

    Topics: Animals; Benzofurans; Bradycardia; Calcium; Carbachol; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Male; Mandelic Acids; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Quinuclidines; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder

2002
Pharmacological effects of darifenacin on human isolated urinary bladder.
    Pharmacology, 2003, Volume: 69, Issue:4

    Topics: Aged; Benzofurans; Carbachol; Electric Stimulation; Female; Humans; Male; Muscarinic Antagonists; Muscle Contraction; Pyrrolidines; Urinary Bladder

2003
Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells.
    Life sciences, 2004, Jan-02, Volume: 74, Issue:7

    Topics: Animals; Benzhydryl Compounds; Benzofurans; Calcium; Calcium Signaling; Carbachol; Cresols; Dose-Response Relationship, Drug; In Vitro Techniques; Inhibitory Concentration 50; Macaca fascicularis; Male; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder

2004
Effects of ageing on muscarinic receptor subtypes and function in rat urinary bladder.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 372, Issue:1

    Topics: Aging; Animals; Atropine; Benzofurans; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Submandibular Gland; Urinary Bladder

2005
M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:2

    Topics: Animals; Benzofurans; Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Pyrrolidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction; Urinary Bladder

2006
M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. II. Denervated rat bladder.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:2

    Topics: Animals; Benzofurans; Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; In Vitro Techniques; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction; Urinary Bladder

2006
Regulation of bladder muscarinic receptor subtypes by experimental pathologies.
    Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:3

    Topics: Age Factors; Animals; Benzofurans; Carbachol; Denervation; Disease Models, Animal; Electric Stimulation; Female; Gene Expression Regulation; Humans; Hypertrophy; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pyrrolidines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; RNA, Messenger; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Bladder, Neurogenic

2006
M2 mediated contractions of human bladder from organ donors is associated with an increase in urothelial muscarinic receptors.
    Neurourology and urodynamics, 2007, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Benzofurans; Carbachol; Child; Child, Preschool; Cholinergic Agonists; Diamines; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pyrrolidines; Receptor, Muscarinic M2; Sus scrofa; Tissue Donors; Urinary Bladder; Urothelium

2007
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
    European urology, 2007, Volume: 52, Issue:2

    Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive

2007
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1

    Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination

2007
Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model.
    European journal of pharmacology, 2007, Oct-31, Volume: 572, Issue:2-3

    Topics: Anesthesia; Animals; Benzhydryl Compounds; Benzofurans; Carbachol; Cholinergic Antagonists; Cresols; Injections, Intra-Arterial; Male; Mandelic Acids; Phenylpropanolamine; Pressure; Pyrrolidines; Quinuclidines; Rabbits; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder

2007
Cholinergic activation of phasic activity in the isolated bladder: possible evidence for M3- and M2-dependent components of a motor/sensory system.
    BJU international, 2007, Volume: 100, Issue:3

    Topics: Animals; Arecoline; Benzofurans; Carbachol; Cholinergic Agonists; Female; Guinea Pigs; Muscarinic Agonists; Piperidines; Pyrrolidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder; Urination

2007
Comparison of human and porcine gastric clasp and sling fiber contraction by M2 and M3 muscarinic receptors.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:4

    Topics: Animals; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Esophagogastric Junction; Humans; Isometric Contraction; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sus scrofa

2010
Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling.
    Science signaling, 2011, Jan-11, Volume: 4, Issue:155

    Topics: Atropine; Benzofurans; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; HEK293 Cells; Humans; Immunohistochemistry; Ionomycin; Ionophores; Membrane Transport Proteins; Muscarinic Antagonists; Olfactory Receptor Neurons; Protein Binding; Pyrrolidines; Receptor, Muscarinic M3; Receptors, G-Protein-Coupled; Receptors, Odorant; Signal Transduction; Transfection

2011
Contractions of the mouse prostate elicited by acetylcholine are mediated by M(3) muscarinic receptors.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:3

    Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Animals; Benzofurans; Body Weight; Carbachol; Cholinergic Agonists; Drug Interactions; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Nicotinic Antagonists; Prazosin; Prostate; Pyrrolidines; Receptor, Muscarinic M3

2011
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
    Urology, 2011, Volume: 78, Issue:6

    Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium

2011
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases.
    Pharmacological research, 2013, Volume: 74

    Topics: Aged; Atropine; Benzofurans; Carbachol; Cell Proliferation; Cells, Cultured; Cholinergic Agonists; Gene Expression; Humans; Male; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Piperidines; Pirenzepine; Proto-Oncogene Proteins c-akt; Pyrrolidines; Receptors, Muscarinic; RNA, Messenger; Urinary Bladder

2013
Effects of Gegen (Puerariae lobatae Radix) water extract on improving detrusor overactivity in spontaneously hypertensive rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Jun-01, Volume: 23, Issue:6

    Topics: Animals; Benzofurans; Carbachol; China; Drugs, Chinese Herbal; Male; Muscle Contraction; Muscle, Smooth; Plant Extracts; Plant Roots; Plants, Medicinal; Pueraria; Pyrrolidines; Rats; Rats, Inbred SHR; Urinary Bladder; Urinary Bladder, Overactive

2016