carbachol and bisindolylmaleimide i

Topics: Adenosine Triphosphate; Animals; Benzopyrans; Carbachol; Cromakalim; Diglycerides; Glyburide; Guanosine Diphosphate; Guinea Pigs; In Vitro Techniques; Indoles; Maleimides; Membrane Potentials; Muscarinic Antagonists; Muscle, Smooth; Potassium Channels; Protein Kinase C; Pyrroles; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Thionucleotides; Urinary Bladder

Topics: Amyloid beta-Protein Precursor; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Isoflavones; Kidney; Maleimides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Tyrosine

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Atropine; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Cholinergic Agents; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate

Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; CHO Cells; COS Cells; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Indoles; Maleimides; Mitogen-Activated Protein Kinase Kinases; Muscarinic Agonists; Nerve Growth Factors; PC12 Cells; Phorbol 12,13-Dibutyrate; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Carbachol; Carbazoles; Cholinergic Agents; Coloring Agents; Enzyme Inhibitors; Fura-2; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Pilocarpine; Propylbenzilylcholine Mustard; Protein Kinase C; Receptors, Cholinergic; Sensitivity and Specificity

Topics: Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gene Expression; Humans; Indoles; Maleimides; Neuroblastoma; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Muscarinic; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adipocytes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Differentiation; GRB2 Adaptor Protein; GTP-Binding Proteins; Histocytochemistry; Indoles; Insulin; Insulin Receptor Substrate Proteins; Maleimides; Mice; Phosphoproteins; Phosphorylation; Protein Kinase C; Proteins; ras Proteins; Receptors, Muscarinic; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Chelating Agents; Dogs; Egtazic Acid; Enzyme Induction; Enzyme Inhibitors; Epidermal Growth Factor; Gastric Fundus; Gene Expression Regulation, Enzymologic; Genes, jun; Histamine; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Parietal Cells, Gastric; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins c-jun; Recombinant Proteins; RNA, Messenger; Thapsigargin; Transcription, Genetic; Transfection

Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding Sites; Binding, Competitive; Bucladesine; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Female; Indoles; Isoproterenol; Isoquinolines; Kinetics; Male; Maleimides; Muscarinic Agonists; Myocardium; N-Methylscopolamine; Propanolamines; Protein Kinase C; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Sulfonamides; Thionucleotides; Tritium

Topics: Astrocytoma; Atropine; Carbachol; Carcinogens; DNA; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioligand Assay; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; DNA-Binding Proteins; DNA, Neoplasm; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Immediate-Early Proteins; Indoles; Kinetics; Maleimides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuroblastoma; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Transcription Factors; Tumor Cells, Cultured; Valproic Acid

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Fatty Acids, Unsaturated; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Heart Ventricles; Hydrazines; Indoles; Inositol Phosphates; Isoenzymes; Maleimides; Norepinephrine; Pertussis Toxin; Phenylalanine; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tritium; Virulence Factors, Bordetella

Topics: Acetophenones; Acetylcholine; Actin Cytoskeleton; Actins; Amino Acid Sequence; Benzopyrans; Biological Transport; Carbachol; Carbazoles; Carcinogens; Cell Membrane; Cell Polarity; Cells, Cultured; Cholinergic Agonists; Cross-Linking Reagents; Cytochalasin D; Diglycerides; Endocytosis; Enzyme Inhibitors; Epithelial Cells; Humans; Indoles; Intestines; Intracellular Signaling Peptides and Proteins; Isoenzymes; Maleimides; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Nucleic Acid Synthesis Inhibitors; Pinocytosis; Protein Kinase C; Protein Kinase C-epsilon; Proteins; Tetradecanoylphorbol Acetate

Topics: Animals; Astrocytoma; Brain Neoplasms; Carbachol; Carcinogens; Cell Division; Cerebral Cortex; Cholinergic Agents; Cold Temperature; DNA Replication; DNA, Neoplasm; Drug Synergism; Electromagnetic Fields; Enzyme Inhibitors; Humans; Indoles; Maleimides; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: Carbachol; Cell Line; Cell Membrane; Enzyme Inhibitors; Humans; Indoles; Intestinal Mucosa; Kinetics; Maleimides; Membrane Potentials; Muscarinic Agonists; Phospholipase D; Propranolol; Protein Kinase C; Receptors, Muscarinic; Tumor Necrosis Factor-alpha

Topics: Carbachol; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection

Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Carbachol; Cholinergic Agonists; HT29 Cells; Humans; Indoles; Inflammatory Bowel Diseases; Intestinal Mucosa; Ions; Maleimides; Membrane Potentials; Propranolol; Receptors, Muscarinic; Tumor Necrosis Factor-alpha

Topics: 1-Butanol; Adrenergic beta-Antagonists; Carbachol; Carcinogens; Chlorides; Cholinergic Agonists; Chromatography, Thin Layer; Diacylglycerol Kinase; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; HT29 Cells; Humans; Indoles; Intestinal Mucosa; Maleimides; Phorbol Esters; Phospholipase D; Propranolol; Protein Kinase C; Pyrimidinones; Receptors, Muscarinic; Signal Transduction; Thiazoles; Tumor Necrosis Factor-alpha

Topics: Astrocytes; Astrocytoma; Carbachol; Carcinogens; Cell Cycle; Cell Division; Cholinergic Agonists; Culture Media, Serum-Free; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Indoles; Isoenzymes; Maleimides; Organometallic Compounds; Protein Kinase C; Protein Kinase C-alpha; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

Topics: Acetylcholinesterase; Amyloid beta-Protein Precursor; Atropine; Carbachol; Cholinesterase Inhibitors; Dichlorvos; Enzyme Inhibitors; Gene Expression Regulation; Glucosephosphate Dehydrogenase; Humans; Indoles; Kinetics; Maleimides; Neuroblastoma; Polymerase Chain Reaction; Prodrugs; Time Factors; Trichlorfon; Tumor Cells, Cultured

Topics: Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dogs; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Histamine; Imidazoles; Indoles; Isoenzymes; Maleimides; NF-kappa B; Nitrobenzenes; Parietal Cells, Gastric; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Agonists; Amides; Animals; Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gastric Fundus; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Phenylephrine; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Stomach; Urinary Bladder

Topics: Atropine; bcl-Associated Death Protein; Carbachol; Carrier Proteins; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; Humans; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Pyrimidines; ras Proteins; Receptors, Muscarinic; Signal Transduction; Tumor Cells, Cultured; Up-Regulation

Topics: Aequorin; Calcium; Carbachol; Cytosol; Down-Regulation; Endoplasmic Reticulum; Enzyme Inhibitors; HeLa Cells; Histamine; Humans; Imidazoles; Indoles; Inositol 1,4,5-Trisphosphate; Maleimides; Mitochondria; Oscillometry; Protein Kinase C; Pyridines; Staurosporine; Time Factors; Transfection

Topics: Alanine; Blotting, Western; Carbachol; Catalytic Domain; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Cholinergic Agonists; Diglycerides; Humans; Indoles; Maleimides; Microscopy, Confocal; Phosphorylation; Plasmids; Protein Conformation; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Time Factors; Transfection

Topics: Animals; Arsenicals; Calcium; Calcium Channels; Carbachol; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endocytosis; Epithelial Cells; Indoles; Maleimides; Muscarinic Agonists; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Muscarinic; Second Messenger Systems; Sucrose; Tetradecanoylphorbol Acetate; Thyroid Gland

Topics: Animals; Calcium Signaling; Carbachol; Cholinergic Agonists; Diglycerides; Gallic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Male; Maleimides; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction

Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Carbachol; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Indoles; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Pertussis Toxin; Protein Isoforms; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate

Topics: Animals; Apoptosis; Carbachol; Caspase 3; Caspases; Cell Survival; Cytochromes c; Cytokines; Enzyme Inhibitors; In Situ Nick-End Labeling; In Vitro Techniques; Indoles; Insulin-Secreting Cells; Lysophospholipids; Male; Maleimides; Nicotinic Agonists; Nitric Oxide Synthase Type II; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sphingosine; Thiazolidines; Type C Phospholipases

Topics: Animals; Carbachol; Cytoplasm; Cytoskeleton; Diacylglycerol Kinase; Diterpenes; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoenzymes; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Scopolamine; Subcellular Fractions

Topics: Acetylcholine; Amyloid beta-Peptides; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Cholinergic Agonists; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Enzyme Inhibitors; In Vitro Techniques; Indoles; Male; Maleimides; Microdialysis; Nicotinic Agonists; Nucleus Accumbens; Peptide Fragments; Protein Kinase C; Pyridines; Rats; Rats, Wistar; Time Factors

Topics: Alternative Splicing; Animals; Atropine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carbachol; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Estrenes; Indoles; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscarinic Agonists; Muscarinic Antagonists; Protein Isoforms; Protein Kinase C; Pyrrolidinones; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Type C Phospholipases

Topics: Amides; Animals; Calcium Signaling; Carbachol; Guinea Pigs; Indoles; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Phenylephrine; Protein Kinase C; Pyridines; Receptor Cross-Talk; Receptors, Adrenergic; Receptors, Muscarinic; rho-Associated Kinases; Signal Transduction; Urinary Bladder

Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Amyloid Precursor Protein Secretases; Animals; Carbachol; Cell Line; Cholinergic Agonists; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Isoenzymes; Maleimides; Membrane Proteins; Mice; Mice, Knockout; Peptide Fragments; Phorbol Esters; Protein Kinase C; PrPC Proteins

Topics: Animals; Bicarbonates; Biotinylation; Calmodulin; Carbachol; Cell Line; Cell Membrane; Cell Polarity; Cholinergic Agonists; Endocytosis; Endosomes; Gene Transfer Techniques; Hydrogen-Ion Concentration; Indoles; Maleimides; Microscopy, Confocal; Monensin; Parotid Gland; Protein Kinase C; Protein Kinase Inhibitors; Protein Transport; Rats; Receptors, Muscarinic; Sodium-Bicarbonate Symporters; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Xenopus laevis

Topics: Analysis of Variance; Animals; Animals, Newborn; Antineoplastic Agents; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels; Carbachol; Cells, Cultured; Enzyme Inhibitors; Female; Indoles; Male; Maleimides; Membrane Potentials; Neurons; Nifedipine; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area

Topics: Acetylcholine; Animals; Carbachol; Cattle; Cell Line; Cell Proliferation; Cholinergic Agonists; Coculture Techniques; Endothelium, Vascular; Enzyme Inhibitors; Hepatocytes; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Maleimides; Muscarinic Antagonists; Muscle, Smooth, Vascular; Oxazoles; Proliferating Cell Nuclear Antigen; Protein Kinase C; Rabbits; Rats; Receptors, Muscarinic; Signal Transduction

Topics: Anilides; Animals; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Enzyme Inhibitors; Eye Proteins; Gene Expression Profiling; Glycoproteins; Immunohistochemistry; Indoles; Lacrimal Apparatus; Macaca mulatta; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; Protein Kinase C; Pyrroles; RNA, Messenger; Signal Transduction; Thiadiazoles

Topics: Amides; Animals; Calcium; Carbachol; Enzyme Inhibitors; Guinea Pigs; Indoles; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Protein Kinase C; Pyridines; rho-Associated Kinases; Signal Transduction; Urinary Bladder Neck Obstruction

Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; Signal Transduction; Urinary Bladder

Topics: Acinar Cells; Animals; Bombesin; Calcimycin; Calcium Ionophores; Calcium Signaling; Carbachol; Cholecystokinin; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gastrointestinal Hormones; Indoles; Intercellular Signaling Peptides and Proteins; Male; Maleimides; Neurotransmitter Agents; Pancreas; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-yes; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin

Topics: Angiotensin II; Animals; Blood Pressure; Brain; Carbachol; Enzyme Inhibitors; Heart Rate; Hypothalamus; Indoles; Male; Maleimides; Models, Animal; Protein Serine-Threonine Kinases; Rats; Rats, Inbred Dahl; Rats, Wistar; Sodium; Sodium Chloride, Dietary; Staurosporine

Topics: Calcium; Carbachol; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Indoles; Maleimides; Protein Kinase C; Quinazolines; Quinolones; Receptors, Muscarinic; Ribosomal Protein S6 Kinases, 90-kDa; Tyrphostins

Topics: Amides; Animals; Carbachol; Cholinergic Agonists; Cystitis, Interstitial; Enzyme Inhibitors; Heparin; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Maleimides; Muscle Contraction; Muscle Relaxants, Central; Protein Kinase C; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Urinary Bladder

Topics: Acetanilides; Adenylyl Cyclase Inhibitors; Aged; Amides; Animals; Carbachol; Cyclic AMP; Female; Humans; Indoles; Isoquinolines; Male; Maleimides; Muscle Relaxation; Muscle, Smooth; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Signal Transduction; Sulfonamides; Swine; Thiazoles; Urinary Bladder; Urological Agents