carbachol has been researched along with afdx 116 in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (19.28) | 18.7374 |
| 1990's | 51 (61.45) | 18.2507 |
| 2000's | 9 (10.84) | 29.6817 |
| 2010's | 6 (7.23) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Kashima, K; Kataoka, K; Kato, M; Kuriyama, K; Ohkuma, S | 1 |
| Narayanan, N; Su, N | 1 |
| Funakoshi, A; Jimi, A; Kono, A; Tateishi, K; Tsuru, M; Wakasugi, H | 1 |
| Buyse, MA; Fraeyman, NH; Lefebvre, RA | 1 |
| Challiss, RA; Nahorski, SR; Whitham, EM | 1 |
| Bhattacharya, SK; Das Gupta, G; Sen, AP; Seth, K; Seth, PK | 1 |
| Gies, JP; Haddad, EB; Landry, Y | 1 |
| Daniel, EE; Janssen, LJ | 1 |
| Choo, LK; Mitchelson, F | 1 |
| Atkins, PT; Kitai, ST; Nishi, K; Surmeier, DJ | 1 |
| Matsumoto, K; Pappano, AJ | 1 |
| Donoff, B; Lad, R; Rangachari, PK | 1 |
| Alonso, MJ; Arribas, S; Balfagón, G; Marín, J; Salaices, M | 1 |
| Akaike, N; Harata, N; Tateishi, N | 1 |
| Chiba, S; Furukawa, Y; Nakane, T | 1 |
| Hersey, SJ; Kajimura, M; Sachs, G; Scott, DR; Wilkes, JM | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Prieto, D; Rivera, L | 1 |
| Richards, MH | 1 |
| Alger, BE; Pitler, TA | 1 |
| Harbon, S; Leiber, D; Marc, S | 1 |
| Fleming, N; Laniyonu, A; Sliwinski-Lis, E | 1 |
| Bloom, JW; Lai, J; Roeske, WR; Yamamura, HI | 1 |
| Hanack, C; Herawi, M; Kopp, R; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A; Tacke, R | 1 |
| Costi, A; Marchi, M; Raiteri, M; Volpe, G | 1 |
| Haga, T; Honda, N; Ichiyama, A; Kajimura, M; Kaneko, E | 1 |
| Bagetta, G; Constanti, A | 1 |
| Araujo, DM; Collier, B; Lapchak, PA; Meaney, MJ; Quirion, R | 1 |
| Ackerman, MS; Korc, M; Roeske, WR | 1 |
| Arrang, JM; Gulat-Marnay, C; Lafitte, A; Schwartz, JC | 1 |
| Goritski, W; Mega, A; Nattie, EE; Wood, J | 1 |
| Kopp, R; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A; Tacke, R | 1 |
| Marchi, M; Raiteri, M | 1 |
| Ghataorre, AS; Lambert, DG; Nahorski, SR | 1 |
| Araujo, DM; Collier, B; Lapchak, PA; Quirion, R | 1 |
| Giachetti, A; Micheletti, R; Montagna, E | 1 |
| Kunysz, EL; Michel, AD; Whiting, RL | 1 |
| Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N | 1 |
| Camus, J; Christophe, J; De Neef, P; Fourmy, D; Pradayrol, L; Robberecht, P; Scemama, JL; Tastenoy, M; Vaysse, N; Waelbroeck, M | 1 |
| Herawi, M; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A | 1 |
| Davidesko, D; Doods, HN; Rinner, I; van Charldorp, KJ; van Zwieten, PA | 1 |
| Chung, FZ; Lai, J; Mei, L; Roeske, WR; Venter, JC; Yamamura, HI | 1 |
| Smith, TL; Yamamura, HI | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Bacman, S; Borda, E; Camusso, JJ; Rodriguez, M; Sterin-Borda, L | 1 |
| Marks, GA; Roffwarg, HP | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Fukui, H; Inagaki, N; Kondou, H | 1 |
| Haass, M; Haunstetter, A; Krüger, C; Kübler, W; Yi, X | 1 |
| Akaike, N; Furukawa, K; Nabekura, J | 1 |
| Anthony, TL; Kreulen, DL | 1 |
| Dauphin, F; Hamel, E; Linville, DG | 1 |
| Allescher, HD; Classen, M; Kurjak, M; Schusdziarra, V | 1 |
| Kaneko, S; Maeda, T; Satoh, M | 1 |
| Greten, H; Mirau, S; Raedler, A; Sievers, J; von Schrenck, T | 1 |
| Chuang, DM; Fukamauchi, F; Hough, C; Saunders, PA | 1 |
| Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M | 1 |
| Bacáková, L; el-Fakahany, EE; Jakubík, J; Tucek, S | 1 |
| Garland, CJ; Hillier, K; Kerr, PM; Wallis, RM | 1 |
| Borda, E; Echagüe, AV; Genaro, A; Leiros, CP; Sterin-Borda, L | 1 |
| Arana, R; Bacman, S; Borda, E; Camusso, JJ; Hubscher, O; Sterin-Borda, L | 1 |
| Akaike, A; Kaneko, S; Maeda, T; Satoh, M; Shimoshige, Y | 1 |
| Aslan, N; Gören, Z; Oktay, S; Onat, F; Ozkutlu, U | 1 |
| Matthews, MR; Zaidi, ZF | 1 |
| Alfonzo, MJ; de Alfonzo, RG; de Becemberg, IL; de Herrera, VN; de Villaroel, SS; Misle, AJ | 1 |
| Komori, S; Nakayama, T; Ohashi, H; Unno, T | 1 |
| Bargas, J; Galarraga, E; Hernández-Echeagaray, E | 1 |
| Cohen, ML; Gomeza, J; Stengel, PW; Wess, J | 1 |
| Christopoulos, A; Lanzafame, A; Mitchelson, F | 1 |
| Cohen, ML; Stengel, PW | 1 |
| Crittenden, EL; García, DM; González, A | 1 |
| Bukharaeva, EA; Magazanik, LG; Nikolsky, EE; Samigullin, D; Vyskocil, F | 1 |
| de Groat, WC; Ng, YK; Wu, HY | 1 |
| Cao, J; Hashiba, K; Kitazawa, T; Komori, S; Taneike, T; Unno, T; Wess, J; Yamada, M | 1 |
| Hirose, K; Kaeriyama, S; Muramatsu, A; Nouchi, H; Sato, M; Shigenobu, K; Shimizu, N; Tanaka, H | 1 |
| Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S | 1 |
| Kajioka, S; Naito, S; Seki, N; Shahab, N | 1 |
| Dehnicke, C; Deisz, RA; Gigout, S; Horn, P; Lehmann, TN; Wierschke, S | 1 |
| Barnes, PJ; Brown, SM; Donnelly, LE; Koarai, A; Nicholson, AG; Sturton, RG | 1 |
| Arrighi, N; Bodei, S; Cosciani Cunico, S; Michel, MC; Sigala, S; Simeone, C; Spano, P; Zani, D | 1 |
| Anderson, RW; Strowbridge, BW | 1 |
| Buyukafsar, K; Cevik, OS; Koyuncu, DD; Sahin, L | 1 |
| Hassanpour, S; Lankarani Mohajer, L; Zendehdel, M | 1 |
2 review(s) available for carbachol and afdx 116
| Article | Year |
|---|---|
Pharmacology and second messenger interactions of cloned muscarinic receptors.
Topics: Animals; Atropine; Carbachol; Cell Line; Humans; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Second Messenger Systems; Transfection | 1991 |
Cardioselective muscarinic antagonists.
Topics: Animals; Carbachol; Cardiotonic Agents; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Dose-Response Relationship, Drug; Heart; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Pirenzepine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
81 other study(ies) available for carbachol and afdx 116
| Article | Year |
|---|---|
Characterization of muscarinic receptor subtypes on rat pancreatic acini: pharmacological identification by secretory responses and binding studies.
Topics: Amylases; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Male; Pancreas; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sincalide | 1992 |
Enhanced chronotropic and inotropic responses of rat myocardium to cholinergic stimulus with aging.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Carbachol; Heart; Heart Rate; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Proteins; Myocardial Contraction; Myocardium; Parasympathetic Nervous System; Parasympatholytics; Parasympathomimetics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred F344 | 1992 |
Acetylcholine regulates pancreastatin secretion from the human pancreastatin-producing cell line (QGP-1N).
Topics: Acetylcholine; Adenoma, Islet Cell; Atropine; Calcimycin; Calcium; Carbachol; Chromogranin A; Gastrin-Releasing Peptide; Humans; Pancreatic Hormones; Pancreatic Neoplasms; Parasympatholytics; Peptides; Piperidines; Pirenzepine; Receptors, Muscarinic; Sincalide; Tumor Cells, Cultured | 1991 |
Study of the muscarinic receptor subtypes in N1E 115 mouse neuroblastoma cells.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Indicators and Reagents; Ligands; Mice; Neuroblastoma; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
M3 muscarinic cholinoceptors are linked to phosphoinositide metabolism in rat cerebellar granule cells.
Topics: Animals; Animals, Newborn; Binding, Competitive; Carbachol; Cerebellum; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Parasympatholytics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats.
Topics: Animals; Arecoline; Carbachol; Carrageenan; Cerebellum; Corpus Striatum; Edema; Female; Foot; Gallamine Triethiodide; Inflammation; Male; Oxotremorine; Pirenzepine; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1991 |
Sialic acid residues as catalysts for M2-muscarinic agonist-receptor interactions.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cell Membrane; Kinetics; Male; Myocardium; Neuraminidase; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Sialic Acids | 1990 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Selective inhibition of responses to carbachol and McN-A-343 in the rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bis-Trimethylammonium Compounds; Carbachol; Cocaine; Electric Stimulation; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pancuronium; Pirenzepine; Rabbits; Vas Deferens | 1990 |
Muscarinic regulation of cyclic AMP metabolism in rat neostriatal cultures.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cyclic AMP; Embryo, Mammalian; Kinetics; N-Methylscopolamine; Neurons; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Carbachol activates a novel sodium current in isolated guinea pig ventricular myocytes via M2 muscarinic receptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cells, Cultured; Electric Conductivity; GTP-Binding Proteins; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Pertussis Toxin; Pirenzepine; Receptors, Muscarinic; Sodium; Virulence Factors, Bordetella | 1991 |
Functional subtyping of muscarinic receptors on canine esophageal mucosa.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Amiloride; Animals; Atropine; Carbachol; Chlorides; Dogs; Electric Conductivity; Esophagus; Female; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mucous Membrane; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Sodium | 1991 |
Presynaptic M2-muscarinic receptors on noradrenergic nerve endings and endothelium-derived M3 receptors in cat cerebral arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Carbachol; Cats; Cerebral Arteries; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasodilation | 1991 |
Acetylcholine receptors in dissociated nucleus basalis of Meynert neurons of the rat.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Membrane Potentials; Neurons; Nicotine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Substantia Innominata | 1991 |
Anti-muscarinic effect of alinidine on acetylcholine-induced vasodilation in isolated and perfused dog coronary arteries.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Parasympatholytics; Piperidines; Pirenzepine; Vasodilation | 1991 |
Muscarinic responses of gastric parietal cells.
Topics: Aminopyrine; Animals; Arachidonic Acids; Calcium; Carbachol; Glucose; Image Processing, Computer-Assisted; Ionomycin; N-Methylscopolamine; Parasympatholytics; Parietal Cells, Gastric; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Ganglia, Parasympathetic; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Piperidines; Pirenzepine; Receptors, Muscarinic; Sheep; Tetraisopropylpyrophosphamide; Urinary Bladder | 1991 |
Activation of the pharmacologically defined M3 muscarinic receptor depolarizes hippocampal pyramidal cells.
Topics: Animals; Carbachol; Evoked Potentials; Hippocampus; In Vitro Techniques; Kinetics; Parasympatholytics; Piperidines; Pirenzepine; Pyramidal Tracts; Rats; Receptors, Muscarinic | 1990 |
Pharmacological evidence for distinct muscarinic receptor subtypes coupled to the inhibition of adenylate cyclase and to the increased generation of inositol phosphates in the guinea pig myometrium.
Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myometrium; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Type C Phospholipases; Uterine Contraction | 1990 |
Muscarinic M3 receptors are coupled to two signal transduction pathways in rat submandibular cells.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Parasympatholytics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Signal Transduction; Submandibular Gland | 1990 |
Amplification of the rat M2 muscarinic receptor gene by the polymerase chain reaction: functional expression of the M2 muscarinic receptor.
Topics: Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cell Line; Cloning, Molecular; Cyclic AMP; Fibroblasts; Furans; Gene Amplification; Gene Expression; Molecular Sequence Data; Muscarinic Antagonists; Naphthalenes; Phosphatidylinositols; Piperidines; Pirenzepine; Plasmids; Polymerase Chain Reaction; Rats; Receptors, Muscarinic; Transfection | 1990 |
Human gastric mucosa expresses glandular M3 subtype of muscarinic receptors.
Topics: Carbachol; Gastric Mucosa; Humans; In Vitro Techniques; N-Methylscopolamine; Parasympatholytics; Piperazines; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Endogenous aspartate release in the rat hippocampus is inhibited by M2 'cardiac' muscarinic receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Calcium; Carbachol; Chromatography, High Pressure Liquid; Heart; Hippocampus; In Vitro Techniques; Male; Myocardium; Neuromuscular Depolarizing Agents; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1990 |
Carbachol-induced potentiation and inhibition of acid secretion by guinea pig gastric gland.
Topics: Aminopyrine; Animals; Atropine; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Male; N-Methylscopolamine; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Muscarinic suppression of the evoked N-wave by oxotremorine-M recorded in the guinea-pig olfactory cortex slice.
Topics: Action Potentials; Animals; Carbachol; Cerebral Cortex; Diamines; Electric Stimulation; Electroencephalography; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Olfactory Bulb; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic | 1990 |
Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: relationship to presynaptic cholinergic markers and binding sites.
Topics: Acetylcholine; Aging; Animals; Brain; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Hippocampus; Male; Muscarinic Antagonists; Nicotinic Antagonists; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Synapses; Thalamus | 1990 |
A cholinergic antagonist identifies a subclass of muscarinic receptors in isolated rat pancreatic acini.
Topics: Amylases; Animals; Atropine; Carbachol; Cerebral Cortex; Dose-Response Relationship, Drug; Kinetics; Male; Myocardium; N-Methylscopolamine; Pancreas; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
Regulation of histamine release and synthesis in the brain by muscarinic receptors.
Topics: Animals; Brain; Carbachol; Histamine Release; Male; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1989 |
Rostral ventrolateral medulla muscarinic receptor involvement in central ventilatory chemosensitivity.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Carbon Dioxide; Cats; Female; Male; Medulla Oblongata; Phrenic Nerve; Pirenzepine; Receptors, Muscarinic; Reference Values; Respiration; Vagotomy | 1989 |
Human HT-29 colon carcinoma cells contain muscarinic M3 receptors coupled to phosphoinositide metabolism.
Topics: Carbachol; Carcinoma; Colonic Neoplasms; Gastric Mucosa; Humans; Inositol Phosphates; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Interaction acetylcholine-glutamate in rat hippocampus: involvement of two subtypes of M-2 muscarinic receptors.
Topics: Acetylcholine; Animals; Carbachol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1989 |
Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1.
Topics: Arecoline; Atropine; Carbachol; Cell Membrane; Humans; Neuroblastoma; Piperidines; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Presynaptic cholinergic mechanisms in the rat cerebellum: evidence for nicotinic, but not muscarinic autoreceptors.
Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebellum; In Vitro Techniques; Kinetics; Ligands; Male; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic | 1989 |
AF-DX 116, a cardioselective muscarinic antagonist.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Cats; Dimethylphenylpiperazinium Iodide; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastric Acid; Gastric Emptying; Guinea Pigs; Heart; Heart Rate; Male; Muscarine; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Pirenzepine; Rats; Receptors, Muscarinic | 1987 |
Functional and direct binding studies using subtype selective muscarinic receptor antagonists.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Dicyclomine; Diphenylacetic Acids; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myocardium; Phenethylamines; Phenylacetates; Pirenzepine; Receptors, Muscarinic | 1988 |
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies.
Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Characterization of muscarinic receptors in human pancreatic membranes.
Topics: Carbachol; Cell Membrane; Humans; Oxotremorine; Pancreas; Pilocarpine; Pirenzepine; Receptors, Muscarinic | 1988 |
Different binding properties of muscarinic M2-receptor subtypes for agonists and antagonists in porcine gastric smooth muscle and mucosa.
Topics: Animals; Binding Sites; Carbachol; Ethylmaleimide; Gastric Mucosa; Muscle, Smooth; Pirenzepine; Receptors, Muscarinic; Swine | 1988 |
Binding of muscarine receptor antagonists to pig coronary smooth muscle.
Topics: Animals; Atropine; Carbachol; Coronary Vessels; Heart Atria; In Vitro Techniques; Muscle, Smooth, Vascular; Piperazines; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Swine; Tritium | 1988 |
The cloned murine M1 muscarinic receptor is associated with the hydrolysis of phosphatidylinositols in transfected murine B82 cells.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Cell Line; Cell Membrane; DNA, Recombinant; Fibroblasts; Guanylyl Imidodiphosphate; Hydrolysis; Mice; Muscarine; Nucleic Acid Hybridization; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Recombinant Proteins; Sequence Homology, Nucleic Acid; Transfection | 1988 |
Competitive inhibition of phosphoinositide hydrolysis by the muscarinic receptor antagonist AF-DX 116 is of low affinity in mouse cerebral cortex.
Topics: Animals; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol Phosphates; Male; Mice; Mice, Inbred C57BL; Pirenzepine; Receptors, Muscarinic; Sugar Phosphates | 1987 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Pharmacological evidence for the existence of different subtypes of muscarinic acetylcholine receptors for phosphoinositide hydrolysis in neonatal versus adult rat atria.
Topics: Animals; Animals, Newborn; Carbachol; Depression, Chemical; Enzyme Inhibitors; Heart; Heart Atria; Hydrolysis; Muscarinic Agonists; Muscarinic Antagonists; Myocardial Contraction; Myocardium; Phosphatidylinositols; Pirenzepine; Rats; Receptors, Muscarinic; Type C Phospholipases | 1995 |
Cholinergic responsiveness of neurons in the ventroposterior thalamus of the anesthetized rat.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Anesthesia, General; Animals; Carbachol; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hypothalamus, Posterior; Iontophoresis; Male; Neurons; Parasympatholytics; Pirenzepine; Rats; Stereotaxic Techniques | 1993 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
Formation of inositol phosphates mediated by M3 muscarinic receptors in type-1 and type-2 astrocytes from neonatal rat cerebral cortex.
Topics: Animals; Animals, Newborn; Astrocytes; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Inositol Phosphates; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Tubocurarine | 1994 |
Muscarinic inhibition of cardiac norepinephrine and neuropeptide Y release during ischemia and reperfusion.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Neuropeptide Y; Norepinephrine; Oxotremorine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic | 1994 |
Nicotinic and muscarinic acetylcholine responses in differentiated PC12 cells.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cell Differentiation; Cell Membrane Permeability; Egtazic Acid; Hexamethonium; Hexamethonium Compounds; Membrane Potentials; Muscarine; Nerve Growth Factors; Nicotine; Nystatin; Parasympatholytics; PC12 Cells; Pirenzepine; Potassium; Receptors, Muscarinic; Receptors, Nicotinic; Tubocurarine | 1994 |
A physiologically-evoked M1-muscarinic depolarization in guinea-pig inferior mesenteric ganglion neurons.
Topics: Action Potentials; Animals; Atropine; Carbachol; Colon; Female; Ganglia, Sympathetic; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Male; Mechanoreceptors; Pirenzepine; Receptors, Muscarinic; Stress, Mechanical | 1994 |
Cholinergic dilatation and constriction of feline cerebral blood vessels are mediated by stimulation of phosphoinositide metabolism via two different muscarinic receptor subtypes.
Topics: Animals; Carbachol; Cats; Cerebral Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Inositol Phosphates; Muscarinic Antagonists; Muscle, Smooth, Vascular; Parasympatholytics; Phosphatidylinositols; Pia Mater; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasoconstriction; Vasodilation | 1994 |
Release of bombesin-like immunoreactivity from synaptosomal membranes isolated from the rat ileum.
Topics: Animals; Atropine; Bombesin; Calcium; Carbachol; Cell Fractionation; Centrifugation, Density Gradient; Ileum; Male; Microscopy, Electron; Pirenzepine; Potassium Chloride; Radioimmunoassay; Rats; Rats, Wistar; Synaptosomes | 1994 |
Bidirectional modulation of long-term potentiation by carbachol via M1 and M2 muscarinic receptors in guinea pig hippocampal mossy fiber-CA3 synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Infusions, Parenteral; Male; Nerve Fibers; Neurons; Parasympatholytics; Pirenzepine; Pyramidal Tracts; Receptors, Muscarinic; Synapses | 1993 |
Characterization of muscarinic receptors on guinea pig gallbladder smooth muscle.
Topics: Animals; Autoradiography; Carbachol; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tetrodotoxin | 1993 |
Agonist-induced down-regulation and antagonist-induced up-regulation of m2- and m3-muscarinic acetylcholine receptor mRNA and protein in cultured cerebellar granule cells.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Down-Regulation; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; RNA, Messenger; Up-Regulation | 1993 |
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C.
Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases | 1993 |
Constitutive activity of the M1-M4 subtypes of muscarinic receptors in transfected CHO cells and of muscarinic receptors in the heart cells revealed by negative antagonists.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; Humans; Inositol Phosphates; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Transfection; Tritium | 1995 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pirenzepine | 1995 |
Endogenous nitric oxide signalling system and the cardiac muscarinic acetylcholine receptor-inotropic response.
Topics: Analysis of Variance; Animals; Atropine; Binding Sites; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Heart Atria; Male; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 1995 |
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Carbamates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Parotid Gland; Phenylcarbamates; Phosphatidylinositols; Piperidines; Pirenzepine; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome | 1996 |
Involvement of M2 receptor in an enhancement of long-term potentiation by carbachol in Schaffer collateral-CA1 synapses of hippocampal slices.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Receptors, Muscarinic; Synapses | 1997 |
Modulation of the pressor response elicited by carbachol and electrical stimulation of the amygdala by muscarinic antagonists in conscious rats.
Topics: Amygdala; Analysis of Variance; Animals; Blood Pressure; Carbachol; Electric Stimulation; Female; Heart Rate; Injections, Intraventricular; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Pirenzepine; Rats; Rats, Sprague-Dawley | 1997 |
Exocytotic release from neuronal cell bodies, dendrites and nerve terminals in sympathetic ganglia of the rat, and its differential regulation.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Dendrites; Exocytosis; Ganglia, Sympathetic; Male; Membrane Potentials; Nerve Endings; Neurons; Nicotine; Oxotremorine; Parasympatholytics; Pirenzepine; Potassium; Rats; Rats, Wistar; Receptors, Muscarinic; Regression Analysis; Synapses | 1997 |
Two opposite signal transducing mechanisms regulate a G-protein-coupled guanylyl cyclase.
Topics: Animals; Carbachol; Cattle; Cell Membrane; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanylate Cyclase; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Trachea; Virulence Factors, Bordetella | 1998 |
M2 and M3 muscarinic receptors couple, respectively, with activation of nonselective cationic channels and potassium channels in intestinal smooth muscle cells.
Topics: Animals; Atropine; Calcium; Carbachol; Guinea Pigs; Male; Muscarinic Agonists; Muscle, Smooth; Piperidines; Pirenzepine; Potassium Channels; Receptors, Muscarinic | 1998 |
3-Alpha-chloro-imperialine, a potent blocker of cholinergic presynaptic modulation of glutamatergic afferents in the rat neostriatum.
Topics: 4-Aminopyridine; Afferent Pathways; Animals; Atropine; Bicuculline; Carbachol; Cevanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Gallamine Triethiodide; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; Neurons; Pirenzepine; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Synapses | 1998 |
M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro.
Topics: Adenosine; Animals; Carbachol; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic | 2000 |
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria.
Topics: Acetylcholine; Allosteric Regulation; Animals; Atropine; Carbachol; Cardiotonic Agents; Dexetimide; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Phthalimides; Pirenzepine; Quaternary Ammonium Compounds; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |
Muscarinic receptor knockout mice: role of muscarinic acetylcholine receptors M(2), M(3), and M(4) in carbamylcholine-induced gallbladder contractility.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Cardiovascular Agents; Cholinesterase Inhibitors; Drug Interactions; Gallbladder; Indomethacin; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Neostigmine; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic | 2002 |
Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill.
Topics: Adenylyl Cyclase Inhibitors; Animals; Arecoline; Atropine; Carbachol; Colforsin; Cyclic AMP; Cytoplasmic Granules; Light; Muscarinic Agonists; Muscarinic Antagonists; Perciformes; Pigment Epithelium of Eye; Piperidines; Pirenzepine; Quaternary Ammonium Compounds; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Retinal Pigments; Second Messenger Systems; Tropicamide | 2004 |
Cholinergic regulation of the evoked quantal release at frog neuromuscular junction.
Topics: Acetylcholine; Action Potentials; Animals; Arecoline; Carbachol; Cholinergic Agonists; Diamines; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neural Conduction; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Pirenzepine; Rana ridibunda; Receptors, Muscarinic; Synaptic Transmission; Tubocurarine | 2004 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Diamines; Electric Stimulation; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Parasympatholytics; Peptides; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2006 |
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Fundus; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Physostigmine; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Stomach | 2007 |
Muscarinic receptor subtypes mediating positive and negative inotropy in the developing chick ventricle.
Topics: Action Potentials; Alkaloids; Animals; Carbachol; Chick Embryo; Dose-Response Relationship, Drug; Furans; Heart Ventricles; Myocardial Contraction; Naphthalenes; Piperidines; Pirenzepine; Receptors, Muscarinic | 2007 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; Signal Transduction; Urinary Bladder | 2012 |
Muscarinic acetylcholine receptor-mediated effects in slices from human epileptogenic cortex.
Topics: Action Potentials; Adult; Biophysics; Carbachol; Cerebral Cortex; Cholinergic Agonists; Drug Combinations; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Female; Humans; In Vitro Techniques; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Pirenzepine; Pyridines; Receptors, Muscarinic; Thiadiazoles | 2012 |
A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.
Topics: Animals; Carbachol; Cholinergic Agonists; Humans; In Vitro Techniques; Lung; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide | 2013 |
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases.
Topics: Aged; Atropine; Benzofurans; Carbachol; Cell Proliferation; Cells, Cultured; Cholinergic Agonists; Gene Expression; Humans; Male; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Piperidines; Pirenzepine; Proto-Oncogene Proteins c-akt; Pyrrolidines; Receptors, Muscarinic; RNA, Messenger; Urinary Bladder | 2013 |
Regulation of persistent activity in hippocampal mossy cells by inhibitory synaptic potentials.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Animals, Newborn; Carbachol; Cholinergic Agonists; Electric Stimulation; Excitatory Amino Acid Agents; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Muscarinic Agonists; Muscarinic Antagonists; Nerve Fibers; Pirenzepine; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 2014 |
Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle.
Topics: Amides; Animals; Atropine; Carbachol; Gastric Mucosa; Muscle Contraction; Muscle, Smooth; Nifedipine; Organ Culture Techniques; Pirenzepine; Pyridines; Ranidae; rho-Associated Kinases | 2018 |
Central muscarinic receptor subtypes (M1 and M3) involved in carbacol-induced hypophagia in neonatal broiler chicken.
Topics: Animals; Animals, Newborn; Behavior, Animal; Carbachol; Chickens; Disease Models, Animal; Eating; Injections, Intraventricular; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M3 | 2020 |