carbachol has been researched along with 1-methyl-3-isobutylxanthine in 197 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 74 (37.56) | 18.7374 |
| 1990's | 87 (44.16) | 18.2507 |
| 2000's | 28 (14.21) | 29.6817 |
| 2010's | 8 (4.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Birnbaumer, L; Entman, ML; Garber, AJ | 1 |
| Handler, JS; Sahib, MK; Schwartz, JH | 1 |
| Boeynaems, JM; Mockel, J; Rocmans, P; Unger, J; Van Herle, A; Van Sande, J | 1 |
| Soll, AH; Wollin, A | 1 |
| Pritchard, ET; Spearman, TN | 1 |
| Forbush, B; Lytle, C; Pon, DJ; Sen, AK; Torchia, J | 1 |
| Hanke, K; Möller, K; Perrin, D; Söling, HD | 1 |
| Decker, GL; Epstein, PN; Means, AR; Ribar, TJ; Yaney, G | 1 |
| Olianas, MC; Onali, P | 1 |
| Hill, A; Lacy, P; Olack, B; Scharp, D | 1 |
| Baux, G; Fossier, P; Tauc, L; Trudeau, LE | 1 |
| MacLeod, KM; Ray, A | 2 |
| Daykin, K; Hall, IP; Townsend, P; Widdop, S | 1 |
| Johnson, RA; Toews, ML | 1 |
| Boege, F; Cantrill, RC; Hahn, M; Heithier, H; Kurstjens, NP | 1 |
| Donaldson, J; Hall, IP; Hill, SJ | 1 |
| Korth, M; Schmied, R | 1 |
| Clausen, C; Dixon, TE; Rich, A | 1 |
| D'Ambra, R; Efrat, S; Fleischer, N; Starr, RG; Surana, M | 1 |
| Bali, JP; Choquet, A; Leonard, A; Magous, R | 1 |
| Johnson, SM | 1 |
| Osborne, NN | 1 |
| Jensen, RT; Maton, PN; Zhang, L | 1 |
| Malinowska, DH | 1 |
| Beavo, J; Jacobson, KL; McPhee, C; Singh, JC; Watson, EL | 1 |
| Goureau, O; Harbon, S; Tanfin, Z | 1 |
| Burnham, BL; Chick, WL; Clark, SA | 1 |
| Meeley, MP; Regunathan, S; Reis, DJ | 1 |
| Atkins, PT; Kitai, ST; Nishi, K; Surmeier, DJ | 1 |
| Bemis, KG; Fleisch, JH; Henry, DP; Marshall, WS; Rinkema, LE; Roman, CR; Russell, WL; Spaethe, SM | 1 |
| Kurosawa, H; Satoh, E; Taira, N; Yanagisawa, T | 1 |
| Inoue, Y; Kaku, K; Kaneko, T; Konishi, Y | 1 |
| Costa, M; Majewski, H | 1 |
| Classen, M; Fürlinger, C; Janczewska, I; Schepp, W; Schmidtler, J; Schusdziarra, V; Weigert, N | 1 |
| Harootunian, A; Machen, TE; Negulescu, PA; Tsien, RY | 1 |
| Nunes, JP; Soares-da-Silva, P; Villanueva, MM | 1 |
| Abdel-Latif, AA; Zhang, YW | 1 |
| Chilvers, ER; Nahorski, SR; Offer, GJ | 1 |
| Brenna, E; Waldum, HL | 1 |
| Ambudkar, IS; Baum, BJ; Dai, YS; Horn, VJ; Kousvelari, EE; Li, M; Wall, SJ; Wolfe, BB; Yasuda, RP; Yeh, CK | 1 |
| Lundquist, I; Panagiotidis, G; Salehi, AA | 1 |
| Malhotra, R; Raufman, JP; Singh, L | 1 |
| Hescheler, J; Wallukat, G; Wobus, AM | 1 |
| Reutter, K; Ruoff, HJ; Schepp, W | 1 |
| Ceriani, T; Moggio, R; Montini, E; Ventura, U | 1 |
| Heim, HK; Ruoff, HJ | 1 |
| Bergqvist, E; Nylander, O; Obrink, KJ | 1 |
| Baum, BJ; Scott, J | 1 |
| Nezu, E; Yoneyama, T; Yoshimura, K | 1 |
| Berger, C; Meyer, W; Scholz, H; Starbatty, J | 1 |
| Harden, TK; Hepler, JR; Hughes, AR; Martin, MW; Nakahata, N | 1 |
| de Haën, C; Halonen, M; Johnson, DG; Palmer, JD; Smith, PF; Thompson, WJ | 1 |
| Ljungström, M; Mårdh, S; Norberg, L; Vega, FV | 1 |
| Harden, TK; Martin, MW; Tanner, LI; Wells, JN | 1 |
| Eckhardt, L; Imamura, K; Kimura, T; Schulz, I | 1 |
| Miederer, S; Ruoff, HJ; Schepp, W; Schusdziarra, V | 1 |
| Hoffman, BB; Thomas, JM | 1 |
| Cochaux, P; Dumont, JE; Swillens, S; Van Sande, J | 1 |
| Bickel, M; Herling, AW | 1 |
| Alvarez, R; Amirian, DA; Chen, MC; Soll, AH; Toomey, M | 1 |
| Pappano, AJ; Rardon, DP | 1 |
| Kelly, E; Nahorski, SR | 2 |
| Engels, J; Korth, M; Schäfer-Korting, M | 1 |
| Andreu, D; Biden, TJ; Bruzzone, R; Meehan, CJ; Merrifield, RB; Trimble, ER | 1 |
| Chiba, T; Fujita, T; Inui, T; Kadowaki, S; Saito, Y; Yamaguchi, A; Yamatani, T | 1 |
| Goldberg, ND; Graeff, RM; Walseth, TF | 1 |
| Athias, P; Ettaiche, M; Variot, N | 1 |
| Aiton, JF; Banks, R; Cramb, G; Rugg, EL | 1 |
| Machen, TE; Negulescu, PA | 1 |
| Bromberg, BB; Cripps, MM; Patchen-Moor, K; Welch, MH | 1 |
| Field, JB; Rani, CS | 1 |
| Collins, SM; Gardner, JD; Jensen, RT; Maton, PN; Sutliff, VE; Zhou, ZC | 1 |
| Askelöf, P; Bartfai, T; Gillenius, P; Westlind-Danielsson, A | 1 |
| Brodsky, WA; Durham, JH; Matons, C; Schneider, ES | 1 |
| Hawthorne, JN; Simmonds, SH; Yagisawa, H | 1 |
| Field, JB; Haraguchi, K; Rani, CS | 1 |
| Baumgold, J; Fishman, PH | 1 |
| Allan, BJ; Ensign, WY; Izutsu, KT; Ramsey, BW; Schubert, MM; Truelove, EL | 1 |
| Taira, N; Yanagisawa, T; Yokoyama, H | 1 |
| Machen, TE; Negulescu, PA; Reenstra, WW | 1 |
| Ishii, K; Murad, F | 1 |
| Conklin, BR; Felder, CC; Ma, AL | 1 |
| Brown, JK; Jones, CA; Madison, JM; Sankary, RM | 1 |
| Baumgold, J; White, T | 1 |
| Forte, JG; Hanzel, DK; Urushidani, T | 1 |
| Black, EW; Cornwell, TL; Lincoln, TM; Strada, SJ; Thompson, WJ | 1 |
| Akil, M; Fisher, SK | 1 |
| Henis, YI; Moscona-Amir, E; Sokolovsky, M | 1 |
| Kamiya, J; Kawai, K; Kobari, T; Maruyama, M | 1 |
| Batzri, S | 1 |
| Soll, AH | 2 |
| Herman, G; Mauduit, P; Rossignol, B | 1 |
| Batzri, S; Harmon, JW; Thompson, WF; Toles, R; Walker, MD | 1 |
| Elander, B; Fellenius, E; Haglund, U; Leth, R; Olbe, L; Rehnberg, O | 1 |
| Dowd, F; Jacobson, KL; Watson, EL | 1 |
| Rosenfeld, GC | 1 |
| Dumont, JE; Erneux, C; Miot, F | 1 |
| Honeyman, TW; Nemecek, GM | 1 |
| Gardner, JD; Jensen, RT; Kasbekar, DK; Raufman, JP | 1 |
| Amirian, DA; Ayalon, A; Sanders, MJ; Soll, AH | 1 |
| Gardner, JD; Jensen, RT; Sutliff, VE; Walker, MD | 1 |
| Hersey, SJ; Norris, SH | 1 |
| Dumont, JE; Erneux, C; Ketelbant, P; Mockel, J; Unger, J | 1 |
| Cochaux, P; Couchie, D; Dumont, JE; Erneux, C; Gervy-Decoster, C; Miot, F; Van Sande, J; Wells, JN | 1 |
| Miederer, SE; Ruoff, HJ; Schepp, W | 1 |
| Burnham, DB; McChesney, DJ; Thurston, KC; Williams, JA | 1 |
| Dartt, DA; Donowitz, M; Joshi, VJ; Mathieu, RS; Sharp, GW | 1 |
| Brown, BL; Dobson, PR; Wojcikiewicz, RJ | 1 |
| Cooper, E; Spaulding, SW | 1 |
| Domboski, L; Krausz, Y; Phang, W; Sharp, GW | 1 |
| Alton, EW; Davidson, DJ; Dorin, JR; Dormer, RL; McPherson, MA; Mills, CL; Porteus, DJ | 1 |
| Giles, WR; Han, X; Shimoni, Y | 1 |
| Bennett, JL; Blair, KL; Pax, RA | 1 |
| Craven, PA; DeRubertis, FR; Studer, RK | 1 |
| Rabkin, SW | 1 |
| Campbell-Thompson, M | 1 |
| Ballati, L; Evangelista, S; Manzini, S; Meini, S | 1 |
| Dent, G; Magnussen, H; Nakashima, M; Rabe, KF; Schudt, C; Tenor, H | 1 |
| Alloatti, G; Gallo, MP; Levi, RC; Penna, C | 1 |
| Beinborn, M; Nompleggi, DJ; Roy, A; Wolfe, MM | 1 |
| Clark, RA; Denning, GM; Welsh, MJ | 1 |
| Osswald, W; Soares-da-Silva, P; Villanueva, MM | 1 |
| Ohshika, H; Sakano, S; Takemura, H | 1 |
| Bolton, TB; Prestwich, SA | 1 |
| Hinds, TR; Storm, DR; Wayman, GA | 1 |
| Endoh, M; Katano, Y | 1 |
| Hildebrand, P; Jensen, RT; Mantey, SA; Mrozinski, JE; Patto, RJ | 1 |
| Barrett, S; Honbo, N; Karliner, JS | 1 |
| Girma, K; Nilsson, G; Romell, B; Seensalu, R | 1 |
| Ando, H; Ando, S; Nomura, H; Takeya, K; Yajima, M | 1 |
| Goldenring, JR; Hidaka, H; Ishikawa, T; Mamiya, N; Modlin, IM; Natsume, A; Tsunoda, Y; Usuda, N; Yasui, K | 1 |
| Bali, JP; Gusdinar, T; Hollande, F; Magous, R | 1 |
| Spessert, R; Vollrath, L | 1 |
| DiJulio, DH; Dowd, FJ; Jacobson, KL; Watson, EL | 1 |
| Moreau, M; Mubagwa, K; Pappano, AJ; Shirayama, T | 1 |
| Dehaye, JP; Turner, RJ; Valdez, IH | 1 |
| Balligand, JL; Belhassen, L; Kelly, RA; Smith, TW | 1 |
| McKenzie, FR; Pouysségur, J | 1 |
| Eschenhagen, T; Grupp, IL; Haverich, A; Herzig, JW; Hirt, S; Kalmár, P; Neumann, J; Schmitz, W; Scholz, H; Stein, B; Wenzlaff, H; Zimmermann, N | 1 |
| Kao, LS; Lin, YJ; Liu, PS | 1 |
| Kaspareit, G; Kirchhefer, U; Neumann, J; Scholz, H | 1 |
| DeSantis, L; Matsumoto, S; Pang, IH; Shade, DL; Steely, HT | 1 |
| Deeg, MA; Verchere, CB | 1 |
| Johnson, DE; Kannan, MS; Shenberger, JS; Shew, RL | 1 |
| Kaneda, T; Nakajyo, S; Shimizu, K; Urakawa, N | 1 |
| Luo, SG; Wojcikiewicz, RJ | 1 |
| Jacobson, KL; Ott, SM; Singh, JC; Storm, DR; Watson, EL; Wu, Z | 1 |
| Azuma, H; Hamasaki, H; Ishida, A; Kamikawatoko, S; Masuda, H; Sato, J; Tokoro, T | 1 |
| Fujimoto, N; Hanawa, T; Kimura, T | 1 |
| Egan, JM; Montrose, MH; Montrose-Rafizadeh, C; Moyes, CD; Roth, J; Wang, Y; Yang, H | 1 |
| Beil, W; Birkholz, C; Sewing, KF; Wagner, S | 1 |
| Cardenas, P; Chacin, J; Hernandez, IM; Lobo, P; Molero, M; Romero, R | 1 |
| Dehne, K; Herrmuth, H; Pfeffer, K; Prinz, C; Schepp, W | 1 |
| Hiramatsu, Y; Yoshimura, K | 1 |
| Akagi, K; Hasebe, K; Nagao, T; Urushidani, T; Watanabe, K | 1 |
| Chen, D; Håkanson, R; Lundquist, I; Nordin, G; Salehi, A | 1 |
| Dobashi, K; Harada, T; Horie, T; Iizuka, K; Mori, M; Nakazawa, T; Yoshii, A | 1 |
| Pappano, AJ; Sakai, R; Shen, JB | 1 |
| Ahrén, B; Karlsson, S; Simonsson, E | 1 |
| Cermak, R; Kuhn, G; Vujicic, Z; Wolffram, S | 1 |
| Beesley, AH; Cook, DI; Karupiah, G; King, NJ; Kunzelmann, K; Young, JA | 1 |
| Beinborn, M; Morales, RE; Nagy, L; Szabo, S; Vattay, P | 1 |
| Bleich, M; Garty, H; Greger, R; Hübner, M; Kunzelmann, K; Levy-Holzman, R; Schreiber, R; Slavik, M; von Hahn, T; Warth, R | 1 |
| Imai, Y; Jiang, B; Pappano, AJ | 1 |
| Bleich, M; Greger, R; Hug, MJ; Kim, JK; Kim, SJ; Pavenstädt, H | 1 |
| André, J; Fruchart, JC; Gonzalez, FJ; Guerre-Millo, M; Peters, JM; Poitout, V; Poulain, P; Reach, G; Rouault, C; Staels, B | 1 |
| Chen, ZY; Huang, Y; Ko, WH; Lau, CW; Law, VW; Yip, WC; Yue, GG | 1 |
| Gálvez, J; González, R; Lorente, MD; Martínez-Augustin, O; Pérez, R; Sánchez de Medina, F; Zarzuelo, A | 1 |
| Akesson, B; Lundquist, I; Panagiotidis, G; Westermark, P | 1 |
| Defer, N; Fischmeister, R; Georget, M; Hanoune, J; Hoerter, J; Lipskaia, L; Lugnier, C; Mateo, P; Vandecasteele, G | 1 |
| Dornonville de la Cour, C; Håkanson, R; Lundquist, I; Salehi, A | 1 |
| Bassani, JW; Bassani, RA; Zafalon, N | 1 |
| Gao, LL; Hescheler, J; Hu, XW; Lai, LL; Li, SY; Liang, HM; Liu, CJ; Luo, HY; Nie, B; Song, YL; Tang, M; Xi, JY | 1 |
| Chou, YC; Fong, JC | 1 |
| Ballester, I; Martínez-Augustin, O; Pérez-Navarro, R; Sánchez de Medina, F; Zarzuelo, A | 1 |
| Carra, GE; Cincunegui, LM; Ibáñez, JE; Saldeña, TA; Saraví, FD | 1 |
| Kim, JJ; Kim, SJ; Lee, J; Lee, JH; Park, JH; Rhee, JC; Rhee, PL | 1 |
| Chen, MH; Du, JY; Ruan, YC; Wu, ZL; Xiang, H; Yang, ZH; Zhou, WL; Zuo, WL | 1 |
| Baharvand, H; Heidari, MH; Hosseini, A; Piryaei, A; Rohani, R; Taei, A | 1 |
| Daenas, C; Gourgoulianis, KI; Hatziefthimiou, AA; Molyvdas, PA | 1 |
| Chatsudthipong, V; Kaewmokul, S; Muanprasat, C | 1 |
| Christensen, GP; Forte, JG; Ghayouri, S; Mettler, SE | 1 |
| Dartt, DA; Funaki, C; Hodges, RR | 1 |
| Hirono, C; Iwasa, Y; Shiba, Y; Shintani, T; Sugita, M | 1 |
| Bonifacio, E; Brigatti, C; Giordano, T; Malosio, ML; Meldolesi, J; Podini, P | 1 |
| Cid, LP; Flores, CA; Sepúlveda, FV | 1 |
| Bonfleur, ML; Boschero, AC; Carneiro, EM; Oliveira, CA; Ribeiro, RA; Vanzela, EC | 1 |
| Bekkali, N; Benninga, MA; Bijlsma, PB; de Jonge, HR; Desjeux, JF; Taminiau, JA; van den Wijngaard, RM; van der Steeg, AF | 1 |
| Kam, WR; Sullivan, DA | 1 |
| Amaral, MD; Bertuzzo, CS; Bonadia, LC; Cardoso, SR; Felício, V; Kmit, A; Kunzelmann, K; Marson, FA; Ramalho, AS; Ribeiro, AF; Ribeiro, JD; Ribeiro, MA; Servidoni, MF; Sousa, L; Sousa, M; Uliyakina, I; Vinagre, AM | 1 |
| Fuentes, J; Márquez, L | 1 |
| Balbo, SL; Bonfleur, ML; Carneiro, EM; Lubaczeuski, C; Maller, AC; Mendes, MC; Ribeiro, RA | 1 |
| Kaneda, T; Sasaki, N; Shimizu, K; Urakawa, N | 1 |
197 other study(ies) available for carbachol and 1-methyl-3-isobutylxanthine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cholinergic stimulation of skeletal muscle alanine and glutamine formation and release. Evidence for mediation by a nicotinic cholinergic receptor and guanosine 3':5'-monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Alanine; Animals; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Glutamine; Hexamethonium Compounds; Muscles; Phosphorylases; Pilocarpine; Quaternary Ammonium Compounds; Rats; Receptors, Cholinergic; Receptors, Nicotinic; Theophylline | 1978 |
Inhibition of toad urinary bladder sodium transport by carbamylcholine: possible role of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Aldosterone; Animals; Biological Transport, Active; Bufo marinus; Calcimycin; Carbachol; Cyclic GMP; In Vitro Techniques; Sodium; Urinary Bladder; Vasopressins | 1978 |
In vitro nonbutanol-extractable iodine release in dog thyroid.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bucladesine; Calcimycin; Carbachol; Cholera Toxin; Dogs; Indomethacin; Ouabain; Thyroglobulin; Thyroid Gland; Thyrotropin | 1979 |
Histamine and cyclic AMP in isolated canine parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Carbachol; Cyclic AMP; Dogs; Gastric Mucosa; Gastrins; Histamine; Oxygen Consumption; Theophylline | 1979 |
Role of cyclic GMP in submandibular gland secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Carbachol; Cyclic GMP; Egtazic Acid; In Vitro Techniques; Male; Parasympathomimetics; Rats; Stimulation, Chemical; Submandibular Gland; Sympathomimetics | 1979 |
The Na-K-Cl cotransporter of avian salt gland. Phosphorylation in response to cAMP-dependent and calcium-dependent secretogogues.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Calcium; Carbachol; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP; Ducks; Kinetics; Membrane Proteins; Phosphates; Phosphorylation; Salt Gland; Sodium-Potassium-Chloride Symporters; Time Factors; Vasoactive Intestinal Peptide | 1992 |
cAMP and Ca(2+)-mediated secretion in parotid acinar cells is associated with reversible changes in the organization of the cytoskeleton.
Topics: 1-Methyl-3-isobutylxanthine; Actins; alpha-Amylases; Animals; Biomarkers; Bucladesine; Calcium; Calcium Chloride; Carbachol; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cytoskeleton; Egtazic Acid; Guinea Pigs; Isoproterenol; Male; Microfilament Proteins; Parotid Gland | 1992 |
Elevated beta-cell calmodulin produces a unique insulin secretory defect in transgenic mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calmodulin; Carbachol; Cells, Cultured; Cytoplasmic Granules; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Transgenic; Microscopy, Electron; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1992 |
Properties of muscarinic-stimulated adenylate cyclase activity in rat olfactory bulb.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Bacterial Toxins; Carbachol; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Neurotransmitter Agents; Olfactory Bulb; Parasympathomimetics; Rats | 1992 |
Automated purification of canine islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Cell Separation; Cell Survival; Centrifugation, Density Gradient; Dogs; Glucose Tolerance Test; Ischemia; Islets of Langerhans; Islets of Langerhans Transplantation; Microbial Collagenase; Tissue Preservation | 1992 |
Xanthine derivatives IBMX and S-9977-2 potentiate transmission at an Aplysia central cholinergic synapse.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Acetylcholinesterase; Animals; Aplysia; Brain; Carbachol; Electrophysiology; Parasympathetic Nervous System; Piperazines; Synapses; Synaptic Transmission; Xanthines | 1992 |
Role of cAMP in the functional interaction of carbachol with different cAMP elevating agents in rabbit atrium.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Analysis of Variance; Animals; Carbachol; Colforsin; Cyclic AMP; Depression, Chemical; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pertussis Toxin; Rabbits; Virulence Factors, Bordetella | 1992 |
Control of cyclic AMP levels in primary cultures of human tracheal smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Carbachol; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoproterenol; Muscle, Smooth; Phosphodiesterase Inhibitors; Propanolamines; Trachea | 1992 |
Protein kinase C activators sensitize cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Carbachol; Colforsin; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Isoproterenol; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Multiple hormone actions: the rises in cAMP and Ca++ in MDCK-cells treated with glucagon and prostaglandin E1 are independent processes.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Dogs; Fluorescent Dyes; Glucagon; Indoles; Isoproterenol; Kidney; Kinetics; Receptors, Gastrointestinal Hormone; Receptors, Glucagon | 1990 |
Modulation of carbachol-induced inositol phosphate formation in bovine tracheal smooth muscle by cyclic AMP phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Albuterol; Animals; Calcium; Carbachol; Cattle; Colforsin; Cyclic AMP; Drug Interactions; In Vitro Techniques; Inositol Phosphates; Male; Membrane Lipids; Muscle, Smooth; Phospholipids; Purinones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1990 |
Muscarinic receptor stimulation and cyclic AMP-dependent effects in guinea-pig ventricular myocardium.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium Channels; Carbachol; Cyclic AMP; Electrophysiology; Female; Guinea Pigs; Heart; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphodiesterase Inhibitors; Receptors, Muscarinic; Sodium | 1990 |
Changes in membrane conductances and areas associated with bicarbonate secretion in turtle bladder.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bicarbonates; Biological Transport, Active; Carbachol; Colchicine; Cyclic AMP; Electric Conductivity; In Vitro Techniques; Membranes; Turtles; Urinary Bladder | 1990 |
Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Carbachol; Colforsin; Cyclic AMP; Drug Synergism; Glipizide; Glucose; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Intracellular coupling of prostaglandin inhibition of acid secretion in isolated rabbit gastric parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Aminopyrine; Animals; Anti-Ulcer Agents; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Gastric Acid; Histamine Antagonists; Inositol Phosphates; Misoprostol; Parietal Cells, Gastric; Rabbits; Theophylline | 1990 |
Opioid inhibition of cholinergic transmission in the guinea-pig ileum is independent of intracellular cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Dynorphins; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Narcotics; Parasympathetic Nervous System; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptic Transmission | 1990 |
Effects of GTP, forskolin, sodium fluoride, serotonin, dopamine, and carbachol on adenylate cyclase in Teleost retina.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Atropine; Carbachol; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fishes; GTP-Binding Proteins; Guanosine Triphosphate; Pertussis Toxin; Retina; Serotonin; Sodium Fluoride; Tetrahydronaphthalenes; Virulence Factors, Bordetella | 1990 |
Characterization of beta-adrenoreceptors on smooth muscle cells from guinea pig stomach.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Carbachol; Cyclic AMP; Epinephrine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Muscle Contraction; Muscle, Smooth; Norepinephrine; Pindolol; Receptors, Adrenergic, beta; Stomach | 1990 |
Cl- channel blockers inhibit acid secretion in rabbit parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anthracenes; Atropine; Carbachol; Chloride Channels; Cimetidine; Colforsin; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Ion Channels; Kinetics; Membrane Proteins; ortho-Aminobenzoates; Rabbits | 1990 |
Regulation of cAMP metabolism in mouse parotid gland by cGMP and calcium.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Hydroxylamine; Hydroxylamines; Mice; Parotid Gland | 1990 |
Prostaglandins and muscarinic agonists induce cyclic AMP attenuation by two distinct mechanisms in the pregnant-rat myometrium. Interaction between cyclic AMP and Ca2+ signals.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Calcium; Carbachol; Cyclic AMP; Dinoprostone; Female; Inositol Phosphates; Intracellular Fluid; Isoproterenol; Myometrium; Pertussis Toxin; Pregnancy; Pregnancy, Animal; Propranolol; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic; Signal Transduction; Stimulation, Chemical; Uterine Contraction; Virulence Factors, Bordetella | 1990 |
Modulation of glucose-induced insulin secretion from a rat clonal beta-cell line.
Topics: 1-Methyl-3-isobutylxanthine; Alanine; Animals; Carbachol; Cell Line; Clone Cells; Clonidine; Colforsin; Dose-Response Relationship, Drug; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Potassium; Rats; Stereoisomerism | 1990 |
Effect of clonidine on second messenger systems in rat adrenal gland.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Glands; Animals; Carbachol; Clonidine; Cyclic AMP; Cyclic GMP; Phosphatidylinositols; Rats; Second Messenger Systems | 1990 |
Muscarinic regulation of cyclic AMP metabolism in rat neostriatal cultures.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cyclic AMP; Embryo, Mammalian; Kinetics; N-Methylscopolamine; Neurons; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Leukotriene receptor antagonism and augmentation of beta-receptor-mediated events by LY171883.
Topics: 1-Methyl-3-isobutylxanthine; Acetophenones; Adrenergic beta-Agonists; Animals; Bronchodilator Agents; Carbachol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Leukotriene E4; Lung; Male; Muscle Contraction; Muscle Relaxation; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Tetrazoles; Theophylline; Trachea | 1990 |
Selective beta 1-receptor full agonists, T-0509 and T-1583, increase the force monophasically and cyclic AMP biphasically in canine ventricular muscle.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Atenolol; Carbachol; Catecholamines; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Ethanolamines; Female; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Propanolamines; Stimulation, Chemical | 1990 |
An in vitro evaluation of adrenergic action on rat pancreatic amylase secretion: lack of stimulatory effect.
Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Carbachol; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Male; Pancreas; Rats; Rats, Inbred Strains; Sincalide; Sympathomimetics; Vasoactive Intestinal Peptide | 1990 |
Inhibitory prejunctional muscarinic receptors at sympathetic nerves do not operate through a cyclic AMP dependent pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Atrial Function; Carbachol; Cyclic AMP; Drug Interactions; Female; Heart Atria; Male; Mice; Myocardium; Nerve Endings; Neural Pathways; Neuromuscular Junction; Norepinephrine; Pertussis Toxin; Protein Kinase C; Rats; Receptors, Muscarinic; Receptors, Purinergic; Staurosporine; Sympathetic Nervous System; Tritium; Virulence Factors, Bordetella | 1990 |
GLP-1-(7-36) amide, -(1-37), and -(1-36) amide: potent cAMP-dependent stimuli of rat parietal cell function.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Biological Transport; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Female; Gastric Acid; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Histamine; In Vitro Techniques; Inositol Phosphates; Kinetics; Parietal Cells, Gastric; Peptide Fragments; Peptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1991 |
Fluorescence measurements of cytosolic free Na concentration, influx and efflux in gastric cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzofurans; Bucladesine; Carbachol; Cytosol; Ethers, Cyclic; Fluorometry; Gastric Mucosa; Kinetics; Parietal Cells, Gastric; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical | 1990 |
Relaxant effects of alpha-human atrial natriuretic peptide on venous smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Purinones; Saphenous Vein; Splenic Artery; Vasodilation | 1991 |
Effects of surgical sympathetic denervation on myo-inositol trisphosphate production and contraction in the dilator and sphincter smooth muscles of the rabbit iris: evidence for interaction between the cyclic AMP and calcium signaling systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Cyclic AMP; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Iris; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Potassium; Rabbits; Reference Values; Signal Transduction; Sympathectomy | 1991 |
Beta-adrenoceptor induced inhibition of muscarinic receptor-stimulated phosphoinositide metabolism is agonist specific in bovine tracheal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cattle; Inositol Phosphates; Isoproterenol; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1991 |
Studies of isolated parietal and enterochromaffin-like cells from the rat.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Carbachol; Cell Count; Cell Separation; Enterochromaffin Cells; Female; Gastric Acid; Gastric Mucosa; Histamine; Parietal Cells, Gastric; Pentagastrin; Rats; Rats, Inbred Strains | 1991 |
Evidence that M3 muscarinic receptors in rat parotid gland couple to two second messenger systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Calcium; Carbachol; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Isoproterenol; Male; Muscarinic Antagonists; Parotid Gland; Precipitin Tests; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; RNA, Messenger; Second Messenger Systems | 1991 |
Effect of the lysosomotropic drug suramin on islet lysosomal enzyme activities and the insulin-secretory response induced by various secretagogues.
Topics: 1-Methyl-3-isobutylxanthine; Acid Phosphatase; Animals; Carbachol; Female; Glyburide; Glycoside Hydrolases; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Islets of Langerhans; Lysosomes; Mice; Suramin | 1991 |
PACAP-38, a novel peptide from ovine hypothalamus, is a potent modulator of amylase release from dispersed acini from rat pancreas.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Bombesin; Calcimycin; Carbachol; Male; Neuropeptides; Pancreas; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Inbred Strains; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide | 1991 |
Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Calcium Channel Blockers; Carbachol; Cell Differentiation; Cell Line; Colforsin; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryo, Nonmammalian; Heart; Heart Rate; Isoproterenol; Membrane Potentials; Myocardium; Parasympathomimetics; Phenylephrine; Prazosin; Stem Cells; Sympathomimetics | 1991 |
Histamine content and release of isolated rat gastric mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Colforsin; Diterpenes; Gastric Mucosa; Histamine; Histamine Release; In Vitro Techniques; Rats | 1985 |
[Actions of ethanol in rupture of the gastric barrier in dogs in vivo].
Topics: 1-Methyl-3-isobutylxanthine; Acetazolamide; Animals; Bucladesine; Carbachol; Dogs; Ethanol; Female; Gastric Juice; Gastric Mucosa; Glucose; Membrane Potentials | 1985 |
Cyclic GMP and acid production in isolated gastric cells of the rat.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Carbachol; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Female; Gastric Acid; Histamine; In Vitro Techniques; Nitrogen; Parietal Cells, Gastric; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1985 |
Dual inhibitory actions of somatostatin on isolated gastric glands.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Aminopyrine; Animals; Bucladesine; Carbachol; Gastric Acid; Histamine Release; In Vitro Techniques; Male; Oxygen Consumption; Parietal Cells, Gastric; Pentagastrin; Rabbits; Somatostatin | 1985 |
Involvement of cyclic AMP and calcium in exocrine protein secretion induced by vasoactive intestinal polypeptide in rat parotid cells.
Topics: 1-Methyl-3-isobutylxanthine; alpha-Amylases; Animals; Calcium; Calcium Radioisotopes; Carbachol; Cyclic AMP; Drug Synergism; Egtazic Acid; In Vitro Techniques; Isoproterenol; Kinetics; Male; Parotid Gland; Rats; Rats, Inbred Strains; Salivary Proteins and Peptides; Vasoactive Intestinal Peptide | 1985 |
Augmentation of isoproterenol-stimulated tissue cyclic AMP level by cholinergic agonists in rat parotid gland.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Oxotremorine; Parotid Gland; Phentolamine; Pilocarpine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains | 1985 |
Effects of the benzimidazole derivatives pimobendan and 2-(4-hydroxy-phenyl)-5-(5-methyl-3-oxo-4,5-dihydro-2H-6- pyridazinyl) benzimidazole . HCl on phosphodiesterase activity and force of contraction in guinea-pig hearts.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclases; Animals; Carbachol; Cardiotonic Agents; Female; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Ouabain; Papillary Muscles; Phenylisopropyladenosine; Phosphodiesterase Inhibitors; Pyridazines | 1985 |
H1-histamine receptors on human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; GTP-Binding Proteins; Histamine; Humans; Pertussis Toxin; Phosphatidylinositols; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Triprolidine; Tritium; Virulence Factors, Bordetella | 1986 |
Bronchodilator activity of a nonxanthine phosphodiesterase inhibitor; 2,4-diamino-5-cyano-6-bromopyridine (compound I).
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-Aminopyridine; Aminopyridines; Animals; Bronchi; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Muscle, Smooth; Phosphodiesterase Inhibitors; Rabbits | 1986 |
Stimulation of acid formation by histamine, carbachol and pentagastrin in isolated pig parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Atropine; Carbachol; Cimetidine; Gastric Acid; Histamine; In Vitro Techniques; Parietal Cells, Gastric; Pentagastrin; Swine | 1986 |
Identification of the phosphodiesterase regulated by muscarinic cholinergic receptors of 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Astrocytoma; Calcium; Carbachol; Cells, Cultured; Chromatography, DEAE-Cellulose; Cyclic AMP; Humans; Isoproterenol; Kinetics; Phosphodiesterase Inhibitors; Receptors, Muscarinic | 1986 |
Ca2+-, phorbol ester-, and cAMP-stimulated enzyme secretion from permeabilized rat pancreatic acini.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amylases; Animals; Calcium; Carbachol; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytoplasmic Granules; Digitonin; Egtazic Acid; Pancreas; Phorbols; Rats; Rats, Inbred Strains; Saponins; Spermine; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
[14C]-aminopyrine accumulation by isolated human parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aminopyrine; Carbachol; Female; Histamine; Humans; In Vitro Techniques; Male; Mast Cells; Middle Aged; Parietal Cells, Gastric; Pentagastrin; Ranitidine; Temperature; Time Factors | 1986 |
Agonist-induced down-regulation of muscarinic cholinergic and alpha 2-adrenergic receptors after inactivation of Ni by pertussis toxin.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; ATPase Inhibitory Protein; Carbachol; Cell Line; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epinephrine; Glioma; Guanylyl Imidodiphosphate; Molecular Weight; NAD; Neuroblastoma; Pertussis Toxin; Proteins; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine; Virulence Factors, Bordetella; Yohimbine | 1986 |
The escape of cyclic AMP from dog thyroid slices exposed to positive and negative regulators.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Carbon Radioisotopes; Cyclic AMP; Dogs; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Mathematics; Potassium Iodide; Probenecid; Prostaglandins A; Radioisotope Dilution Technique; Thyroid Gland; Thyrotropin; Tritium | 1986 |
The stimulatory effect of forskolin on gastric acid secretion in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cimetidine; Colforsin; Dose-Response Relationship, Drug; Gastric Acid; Histamine; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors | 1986 |
Prostanoid inhibition of canine parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aminopyrine; Animals; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Histamine; Parietal Cells, Gastric; Prostaglandins E; Prostaglandins E, Synthetic; Stimulation, Chemical | 1986 |
Carbachol inhibits electrophysiological effects of cyclic AMP in ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cell Separation; Colforsin; Cyclic AMP; Electrophysiology; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Myocardium; Time Factors | 1986 |
Specific inhibition of dopamine D-1-mediated cyclic AMP formation by dopamine D-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Alprostadil; Animals; Benzazepines; Carbachol; Cholera Toxin; Corpus Striatum; Cyclic AMP; Isoproterenol; Morphine; Phenethylamines; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Opioid; Vasoactive Intestinal Peptide | 1986 |
Influence of phosphodiesterase inhibition and of carbachol on inotropic effects of 8-substituted cyclic AMP analogues.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors | 1987 |
Secretin stimulates cyclic AMP and inositol trisphosphate production in rat pancreatic acinar tissue by two fully independent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Calcium; Carbachol; Cyclic AMP; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Secretin; Structure-Activity Relationship; Sugar Phosphates | 1987 |
Glucose stimulates insulin release without altering cyclic AMP production or inositolphospholipid turnover in freshly obtained human insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Carbachol; Colforsin; Cyclic AMP; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Kinetics; Pancreatic Neoplasms; Phosphatidylinositols | 1987 |
The dynamics of cGMP metabolism in neuroblastoma N1E-115 cells determined by 18O labeling of guanine nucleotide alpha-phosphoryls.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenine Nucleotides; Animals; Carbachol; Cell Line; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Isotope Labeling; Kinetics; Neuroblastoma; Nitroprusside; Oxygen Radioisotopes | 1987 |
Dopamine D-2 receptors inhibit D-1 stimulated cyclic AMP accumulation in striatum but not limbic forebrain.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Appetite Depressants; Benzazepines; Carbachol; Corpus Striatum; Cyclic AMP; Ergolines; In Vitro Techniques; Limbic System; Male; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Muscarinic; Sulpiride | 1987 |
Physiological effects of carbamylcholine, cyclic GMP and related agents on isolated rat ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic GMP; Electrophysiology; Heart; Heart Rate; Isoproterenol; Myocardial Contraction; Rats | 1987 |
Actions of atrial natriuretic peptide (ANP) on cyclic nucleotide concentrations and phosphatidylinositol turnover in ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Inositol Phosphates; Isoproterenol; Male; Myocardium; Nitroprusside; Nucleotides, Cyclic; Phosphatidylinositols; Propranolol; Rabbits | 1987 |
Intracellular Ca regulation during secretagogue stimulation of the parietal cell.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Calcium; Carbachol; Histamine; Intracellular Membranes; Male; Parietal Cells, Gastric; Rabbits; Receptors, Drug; Receptors, Histamine; Temperature | 1988 |
Adrenocorticotropic hormone stimulation of lacrimal peroxidase secretion.
Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Lacrimal Apparatus; Male; Peroxidases; Phenylephrine; Rats; Rats, Inbred F344; Secretory Rate; Time Factors | 1987 |
Comparison of effects of thyrotropin, phorbol esters, norepinephrine, and carbachol on iodide organification in dog thyroid slices, follicles, and cultured cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Bucladesine; Carbachol; Cyclic AMP; Dogs; In Vitro Techniques; Iodides; Kinetics; Norepinephrine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Characterization of receptors for calcitonin gene-related peptide on gastric smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Carbachol; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Male; Muscle Contraction; Muscle, Smooth; Neuropeptides; Rats; Receptors, Calcitonin; Receptors, Cell Surface; Stomach | 1988 |
Chronic exposure to pertussis toxin alters muscarinic receptor-mediated regulation of cyclic AMP metabolism in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Atropine; Carbachol; Cyclic AMP; Glioma; Hybrid Cells; Neuroblastoma; Pertussis Toxin; Receptors, Muscarinic; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Alkali secretion in the turtle bladder: up-regulation by the phospho-inositol cascade and inhibition by diphenylamine carboxylate (DPC).
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carbachol; Choline; Cyclic AMP; Hydrogen-Ion Concentration; ortho-Aminobenzoates; Phosphatidylinositols; Theophylline; Turtles; Urinary Bladder; Vasoactive Intestinal Peptide | 1988 |
The muscarinic receptor of rat pituitary GH3 cells is coupled with adenylate cyclase inhibition, but not with phosphoinositide turnover.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carbachol; Inositol Phosphates; N-Methylscopolamine; Phosphatidylinositols; Pirenzepine; Pituitary Gland; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1988 |
Effects of thyrotropin, carbachol, and protein kinase-C stimulators on glucose transport and glucose oxidation by primary cultures of dog thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium Channel Blockers; Carbachol; Cells, Cultured; Cholera Toxin; Cyclic AMP; Deoxy Sugars; Deoxyglucose; Dogs; Glucose; Kinetics; Norepinephrine; Protein Kinase C; Reference Values; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Muscarinic receptor-mediated increase in cAMP levels in SK-N-SH human neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Humans; Kinetics; Neuroblastoma; Oxotremorine; Pertussis Toxin; Receptors, Muscarinic; Virulence Factors, Bordetella | 1988 |
Potassium release in labial glands from controls and patients with cystic fibrosis.
Topics: 1-Methyl-3-isobutylxanthine; Carbachol; Cystic Fibrosis; Humans; Potassium; Salivary Glands; Salivary Glands, Minor | 1989 |
Details of mode and mechanism of action of denopamine, a new orally active cardiotonic agent with affinity for beta 1-receptors.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Dogs; Drug Interactions; Ethanolamines; Female; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Propanolamines; Receptors, Adrenergic, beta; Time Factors | 1988 |
Intracellular Ca requirements for stimulus-secretion coupling in parietal cell.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Calcium; Carbachol; Cyclic AMP; Cytosol; Egtazic Acid; Histamine; In Vitro Techniques; Kinetics; Parietal Cells, Gastric; Rabbits | 1989 |
ANP relaxes bovine tracheal smooth muscle and increases cGMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Carbachol; Cattle; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Serotonin; Trachea | 1989 |
Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cell Line; Cell Transformation, Neoplastic; Cholecystokinin; Cricetinae; Cyclic AMP; Dinoprostone; Female; Kinetics; Ovary; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Differential effects of prostaglandin E2 on contractions of airway smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Atropine; Carbachol; Dimethylphenylpiperazinium Iodide; Dinoprostone; Dogs; Histamine; In Vitro Techniques; Kinetics; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Propranolol; Tetrodotoxin; Trachea | 1989 |
Pharmacological differences between muscarinic receptors coupled to phosphoinositide turnover and those coupled to adenylate cyclase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Carbachol; Humans; N-Methylscopolamine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured | 1989 |
Characterization of an 80-kDa phosphoprotein involved in parietal cell stimulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphatases; Animals; Bucladesine; Carbachol; Electrophoresis, Gel, Two-Dimensional; H(+)-K(+)-Exchanging ATPase; Histamine; In Vitro Techniques; Membrane Proteins; Molecular Weight; Parietal Cells, Gastric; Phosphoproteins; Phosphorylation; Rabbits | 1989 |
Fura 2 analysis of cytosolic calcium regulation in elutriated rat gastric parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzofurans; Calcium; Carbachol; Colforsin; Cytosol; Fluorescent Dyes; Fura-2; Histamine; Homeostasis; In Vitro Techniques; Kinetics; Male; Molecular Weight; Parietal Cells, Gastric; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1989 |
Muscarinic receptor-stimulated phosphoinositide turnover in human SK-N-SH neuroblastoma cells: differential inhibition by agents that elevate cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Bucladesine; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Humans; Intracellular Membranes; Ligands; Neuroblastoma; Phosphatidylinositols; Receptors, Muscarinic; Theophylline; Tumor Cells, Cultured | 1989 |
Aging of rat heart myocytes disrupts muscarinic receptor coupling that leads to inhibition of cAMP accumulation and alters the pathway of muscarinic-stimulated phosphoinositide hydrolysis.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Binding, Competitive; Carbachol; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Heart; Isoproterenol; Kinetics; Myocardium; Norepinephrine; Oxotremorine; Phosphatidylinositols; Rats; Receptors, Muscarinic; Time Factors | 1989 |
Characterization of MS-857, a new and potent cardiotonic agent, in isolated mammalian cardiac muscles.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cardiotonic Agents; Cats; Cyclic AMP; Cyclic GMP; Dogs; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoquinolines; Macaca mulatta; Male; Milrinone; Myocardial Contraction; Pyridones; Rabbits; Rats; Rats, Inbred Strains; Reserpine; Tetrahydroisoquinolines | 1989 |
Tricyclic antidepressants and acid secretory response of rabbit gastric cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bucladesine; Carbachol; Cyclic AMP; Gastric Acid; Gastric Mucosa; Histamine; Imipramine; Nortriptyline; Oxygen Consumption; Parietal Cells, Gastric; Rabbits; Receptors, Histamine; Time Factors | 1985 |
Specific inhibition by prostaglandins E2 and I2 of histamine-stimulated [14C]aminopyrine accumulation and cyclic adenosine monophosphate generation by isolated canine parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Carbachol; Cyclic AMP; Dogs; Epoprostenol; Gastric Mucosa; Gastrins; Histamine Antagonists; In Vitro Techniques; Prostaglandins; Prostaglandins E | 1980 |
A tentative explanation of the stimulatory effect of methylxanthines (pentoxifylline and isobutylmethylxanthine) on the secretory process in rat extraorbital lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Lacrimal Apparatus; Male; Norepinephrine; Pentoxifylline; Proteins; Rats; Rats, Inbred Strains; Sympathomimetics; Theobromine; Theophylline; Xanthines | 1981 |
Secretion of intrinsic factor from dispersed mucosal cells isolated from guinea pig and rabbit stomach.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cimetidine; Gastric Mucosa; Gastrins; Guinea Pigs; Histamine; In Vitro Techniques; Intrinsic Factor; Kinetics; Rabbits | 1982 |
Potentiating interactions of gastric stimulants on [14 C] aminopyrine accumulation by isolated canine parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Carbachol; Dogs; Drug Synergism; Gastrins; Histamine; Histamine Antagonists; Stomach | 1982 |
The effects of secretagogues of isolated human gastric glands.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aminopyrine; Bucladesine; Carbachol; Duodenal Ulcer; Gastric Acid; Gastric Mucosa; Histamine; Humans; In Vitro Techniques; Middle Aged; Pentagastrin; Stomach Ulcer | 1982 |
Does cyclic GMP mediate amylase release from mouse parotid acini?
Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Azides; Bucladesine; Carbachol; Cyclic GMP; Hydroxylamines; Mice; Nitroprusside; Parotid Gland; Sodium Azide | 1982 |
Pirenzepine (LS 519): a weak inhibitor of acid secretion by isolated rat parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atropine; Benzodiazepinones; Bucladesine; Carbachol; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Pirenzepine; Rats | 1982 |
The involvement of a calmodulin-dependent phosphodiesterase in the negative control of carbamylcholine on cyclic AMP levels in dog thyroid slices.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium-Binding Proteins; Calmodulin; Carbachol; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Dogs; In Vitro Techniques; Kinetics; Thyroid Gland | 1983 |
The role of cyclic nucleotide phosphodiesterase in the inhibition of cyclic AMP accumulation by carbachol and phosphatidate.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Female; Fibroblasts; Humans; Phosphatidic Acids; Trifluoperazine | 1982 |
Potentiation of pepsinogen secretion from dispersed glands from rat stomach.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; Gastric Mucosa; In Vitro Techniques; Kinetics; Male; Pepsinogens; Rats; Rats, Inbred Strains; Secretin; Sincalide; Vasoactive Intestinal Peptide | 1983 |
Regulation of pepsinogen release from canine chief cells in primary monolayer culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cells, Cultured; Dogs; Gastric Fundus; Gastric Mucosa; Histamine; Kinetics; L-Lactate Dehydrogenase; Pepsinogens; Secretin; Vasoactive Intestinal Peptide | 1983 |
Effects of inhibitors of cyclic nucleotide phosphodiesterase on actions of cholecystokinin, bombesin, and carbachol on pancreatic acini.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amylases; Animals; Bombesin; Carbachol; Cyclic AMP; Guinea Pigs; Imidazoles; In Vitro Techniques; Pancreas; Peptides; Sincalide; Theophylline | 1983 |
pH dependence of pepsinogen and acid secretion in isolated gastric glands.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Aminopyrine; Animals; Carbachol; Exocrine Glands; Gastric Juice; Gastric Mucosa; Histamine; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Male; Oxygen Consumption; Pepsinogens; Rabbits | 1983 |
Mechanism of cholinergic inhibition of dog thyroid secretion in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Carbachol; Cyclic AMP; Cytochalasins; Dogs; Egtazic Acid; In Vitro Techniques; Iodides; Kinetics; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1984 |
Negative regulation of cyclic AMP levels by activation of cyclic nucleotide phosphodiesterases: the example of the dog thyroid.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Adenylyl Cyclases; Animals; Calcium; Carbachol; Cyclic AMP; Dinoprost; Dogs; Egtazic Acid; Enzyme Activation; In Vitro Techniques; Prostaglandins F; Thyroid Gland | 1984 |
Intrinsic factor secretion from isolated human gastric mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carbachol; Female; Gastric Mucosa; Histamine; Humans; In Vitro Techniques; Intrinsic Factor; Kinetics; Male; Middle Aged; Parietal Cells, Gastric; Pentagastrin; Protein Binding; Stomach Ulcer; Vitamin B 12 | 1984 |
Interaction of cholecystokinin and vasoactive intestinal polypeptide on function of mouse pancreatic acini in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Calcimycin; Carbachol; Cholecystokinin; Deoxyglucose; Drug Interactions; In Vitro Techniques; Male; Mice; Pancreas; Secretin; Vasoactive Intestinal Peptide | 1984 |
Cyclic nucleotide-dependent enzyme secretion in the rat lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Carbachol; Cardiotonic Agents; Colforsin; Cyclic GMP; Diterpenes; In Vitro Techniques; Isoenzymes; Lacrimal Apparatus; Male; Peroxidase; Peroxidases; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors | 1984 |
Muscarinic acetylcholine receptor activation causes inhibition of cyclic AMP accumulation, prolactin and growth hormone secretion in GH3 rat anterior pituitary tumour cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Carbachol; Cell Line; Cyclic AMP; Growth Hormone; Kinetics; Oxotremorine; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Rats; Receptors, Muscarinic; Vasoactive Intestinal Peptide | 1984 |
Histone and high mobility group protein phosphorylation in the thyroid: regulation by cyclic nucleotides.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cattle; Colforsin; Diterpenes; High Mobility Group Proteins; Histones; Nucleotides, Cyclic; Phosphorylation; Sodium Nitrite; Thyroid Gland | 1984 |
Mechanisms of synergism between glucose and cAMP on stimulation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biomechanical Phenomena; Calcium; Carbachol; Choline; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Glucose; Insulin; Ion Exchange; Islets of Langerhans; Isotonic Solutions; Male; Ouabain; Potassium Chloride; Rats; Rats, Inbred Strains; Ringer's Solution; Sodium; Stimulation, Chemical; Verapamil | 1984 |
Decreased beta-adrenergic stimulation of glycoprotein secretion in CF mice submandibular glands: reversal by the methylxanthine, IBMX.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Amylases; Animals; Carbachol; Cyclic AMP; Cystic Fibrosis; Glucosamine; Glycoproteins; Heterozygote; Humans; Male; Mice; Mice, Mutant Strains; Pancreas; Submandibular Gland; Thionucleotides | 1995 |
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides | 1995 |
Serotonin and acetylcholine: further analysis of praziquantel-induced contraction of magnesium-paralysed Schistosoma mansoni.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Amifampridine; Animals; Arecoline; Carbachol; Colforsin; Dose-Response Relationship, Drug; In Vitro Techniques; Ions; Magnesium; Male; Muscle Contraction; Paralysis; Phorbol 12,13-Dibutyrate; Praziquantel; Schistosoma mansoni; Serotonin | 1993 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
Effect of indapamide on cyclic adenosine 3',5'-monophosphate signal transduction system in isolated adult rat cardiomyocytes from normal myocardium and cardiac hypertrophy.
Topics: 1-Methyl-3-isobutylxanthine; Angiotensin II; Animals; Binding, Competitive; Carbachol; Cardiomegaly; Colforsin; Cyclic AMP; Heart; In Vitro Techniques; Indapamide; Isoproterenol; Male; Myocardium; Rats; Rats, Wistar; Signal Transduction | 1993 |
Secretagogue-induced [14C]aminopyrine uptake in isolated equine parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Biological Transport; Carbachol; Carbon Radioisotopes; Cells, Cultured; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Histamine; Horses; Humans; Kinetics; Male; Parietal Cells, Gastric; Pentagastrin; Rats; Species Specificity; Swine; Time Factors | 1994 |
Isbufylline, a xanthine derivative, inhibits bronchoconstrictor responses produced by stimulation of capsaicin-sensitive sensory nerves in guinea-pig: 'In vitro' and 'in vivo' evidence.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Capsaicin; Carbachol; Choline; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Neurons, Afferent; Stimulation, Chemical; Theophylline; Trachea; Vagus Nerve | 1993 |
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Antihypertensive Agents; Carbachol; Colforsin; Cytosol; Dinoprost; Dose-Response Relationship, Drug; Female; Humans; Isoenzymes; Kinetics; Lung Neoplasms; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Pyridazines; Pyrrolidinones; Rolipram | 1994 |
Guanylate-cyclase-mediated inhibition of cardiac ICa by carbachol and sodium nitroprusside.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channels; Carbachol; Cell Membrane; Guanylate Cyclase; Guinea Pigs; Heart; Methylene Blue; Myocardium; Nitroprusside; Pertussis Toxin; Virulence Factors, Bordetella | 1994 |
The effect of recombinant cytokines on [14C]-aminopyrine accumulation by isolated canine parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Carbachol; Carbon Radioisotopes; Cells, Cultured; Dogs; Histamine Antagonists; Humans; Indomethacin; Interleukin-1; Parietal Cells, Gastric; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
cAMP and inositol 1,4,5-trisphosphate increase Ca2+ in HT-29 cells by activating different Ca2+ influx pathways.
Topics: 1-Methyl-3-isobutylxanthine; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Intestinal Mucosa | 1994 |
Effect of sympathetic denervation on the relaxing responses of rabbit arterial smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Colforsin; Cyclic AMP; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitroprusside; Purinones; Rabbits; Sympathectomy, Chemical; Vasodilation | 1994 |
Multiple calcium signaling pathways in Mardin-Darby canine kidney cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Biological Transport; Bradykinin; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Line; Cells, Cultured; Cyclic AMP; Dogs; Epithelium; Fura-2; Inositol 1,4,5-Trisphosphate; Kidney; Signal Transduction; Type C Phospholipases | 1994 |
Inhibition of muscarinic receptor-induced inositol phospholipid hydrolysis by caffeine, beta-adrenoceptors and protein kinase C in intestinal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Caffeine; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Cyclic AMP; Diglycerides; Gallopamil; Guinea Pigs; Hydrolysis; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Intestine, Small; Isoproterenol; Muscle, Smooth; Protein Kinase C; Receptors, Adrenergic, beta; Receptors, Muscarinic; Ryanodine; Stereoisomerism; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Hormone stimulation of type III adenylyl cyclase induces Ca2+ oscillations in HEK-293 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Glucagon; Humans; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Isoquinolines; Kidney; Kinetics; Models, Biological; Oscillometry; Phosphatidylinositols; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, Glucagon; Signal Transduction; Time Factors | 1995 |
Cyclic AMP metabolism in intact rat ventricular cardiac myocytes: interaction of carbachol with isoproterenol and 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cyclic AMP; Drug Interactions; Heart Ventricles; Isoproterenol; Male; Myocardium; Phosphoric Diester Hydrolases; Propranolol; Rats; Rats, Wistar | 1993 |
Pancreatic acini possess endothelin receptors whose internalization is regulated by PLC-activating agents.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Benzodiazepinones; Bombesin; Calcimycin; Carbachol; Cholecystokinin; Cyclic AMP; Devazepide; Endothelins; Enzyme Activation; In Vitro Techniques; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Secretin; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vasoactive Intestinal Peptide | 1993 |
Alpha 1-adrenoceptor-mediated inhibition of cellular cAMP accumulation in neonatal rat ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Animals, Newborn; Carbachol; Cells, Cultured; Cyclic AMP; GTP-Binding Proteins; Heart Ventricles; Norepinephrine; Pertussis Toxin; Phosphoric Diester Hydrolases; Radioimmunoassay; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Substrate Specificity; Virulence Factors, Bordetella | 1993 |
Effects of carbachol and gastrin on 14C-aminopyrine accumulated in rabbit gastric glands and cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Atropine; Carbachol; Carbon Radioisotopes; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; In Vitro Techniques; Parietal Cells, Gastric; Rabbits; Stimulation, Chemical; Time Factors | 1993 |
A pharmacological investigation of the contribution of muscarinic receptor-linked potassium channels to the reversal by carbachol of positive inotropic responses of rabbit left atrium to cyclic AMP-generating agents.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Function, Left; Carbachol; Cardiotonic Agents; Colforsin; Cyclic AMP; Depression, Chemical; Electric Stimulation; Female; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Pertussis Toxin; Potassium Channels; Rabbits; Receptors, Muscarinic; Virulence Factors, Bordetella | 1993 |
Relaxing effect of vesnarinone (OPC-8212) on the tracheal muscle strips isolated from guinea pigs.
Topics: 1-Methyl-3-isobutylxanthine; Airway Resistance; Animals; Carbachol; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Potassium; Propranolol; Pyrazines; Quinolines; Reserpine; Trachea | 1993 |
Inhibition of acid secretion in gastric parietal cells by the Ca2+/calmodulin-dependent protein kinase II inhibitor KN-93.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cimetidine; Colforsin; Cyclic AMP; Gastric Acid; H(+)-K(+)-Exchanging ATPase; Histamine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Microscopy, Electron; Parietal Cells, Gastric; Protein Kinase Inhibitors; Rabbits; Sulfonamides | 1993 |
Neurohormonal regulation of histamine release from isolated rabbit fundic mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Carbachol; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Gastric Fundus; Gastric Mucosa; Gastrins; Histamine Release; Male; Muscarinic Antagonists; Prostaglandins; Rabbits; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1993 |
Muscarinic agonists have no measurable effect on cGMP formation of rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Bethanechol; Bethanechol Compounds; Calcium; Carbachol; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Kinetics; Male; Nitroprusside; Norepinephrine; Parasympathomimetics; Pineal Gland; Rats; Rats, Sprague-Dawley; Theophylline | 1993 |
Biphasic effects of carbachol on stimulated cAMP accumulation in mouse parotid acini.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Carbachol; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred Strains; Parotid Gland | 1993 |
Effects of PDE inhibitors and carbachol on the L-type Ca current in guinea pig ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channels; Carbachol; Chloride Channels; Cyclic AMP; Cyclic GMP; Electric Conductivity; Guinea Pigs; Heart Ventricles; Myocardium; Papaverine; Parasympathomimetics; Phosphodiesterase Inhibitors | 1993 |
Beta-adrenergic stimulation and cAMP mobilize Ca2+ from an IP3-insensitive pool in rat submandibular granular ducts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Alkaloids; Animals; Atenolol; Atropine; Calcium; Carbachol; Cyclic AMP; Epinephrine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Isoquinolines; Kinetics; Male; Phentolamine; Piperazines; Propanolamines; Propranolol; Protein Kinase C; Protein Kinase Inhibitors; Putrescine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Staurosporine; Submandibular Gland | 1993 |
Nitric oxide synthase (NOS3) and contractile responsiveness to adrenergic and cholinergic agonists in the heart. Regulation of NOS3 transcription in vitro and in vivo by cyclic adenosine monophosphate in rat cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Colforsin; Cyclic AMP; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Heart; Isoproterenol; Kinetics; Male; Milrinone; Myocardial Contraction; Myocardium; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Pyridones; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1996 |
cAMP-mediated growth inhibition in fibroblasts is not mediated via mitogen-activated protein (MAP) kinase (ERK) inhibition. cAMP-dependent protein kinase induces a temporal shift in growth factor-stimulated MAP kinases.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Division; Cell Line; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fibroblast Growth Factor 2; Fibroblasts; Humans; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Thrombin | 1996 |
Positive inotropic effects of the calcium sensitizer CGP 48506 in failing human myocardium.
Topics: 1-Methyl-3-isobutylxanthine; Azocines; Calcium; Carbachol; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart; Humans; Kinetics; Muscle Contraction | 1996 |
Effects of caffeine on Ca2+ fluxes and secretion in bovine chromaffin cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Medulla; Animals; Bucladesine; Caffeine; Calcium; Calcium-Transporting ATPases; Carbachol; Catecholamines; Cattle; Colforsin; Dimethylphenylpiperazinium Iodide; Inositol Phosphates; Nicotinic Agonists; Phosphodiesterase Inhibitors; Terpenes; Thapsigargin; Veratridine | 1995 |
Sodium fluoride attenuates the negative inotropic effects of muscarinic M2 and adenosine receptor agonists.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cyclic AMP; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Isoproterenol; Muscarinic Agonists; Myocardial Contraction; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Sodium Fluoride | 1995 |
Presence of functional type B natriuretic peptide receptor in human ocular cells.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcium; Carbachol; Cell Line, Transformed; Cells, Cultured; Ciliary Body; Cyclic GMP; Guanylate Cyclase; Humans; Intraocular Pressure; Kinetics; Muscle Contraction; Natriuretic Peptide, C-Type; Proteins; Receptors, Atrial Natriuretic Factor; Simian virus 40; Trabecular Meshwork | 1996 |
Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cycloheximide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Pancreatic Neoplasms; Peptide Fragments; Phospholipase D; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Relaxation of porcine tracheal smooth muscle by parathyroid hormone-related protein.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Carbachol; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Large-Conductance Calcium-Activated Potassium Channels; Muscle Relaxation; Muscle, Smooth; Parasympathomimetics; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Phosphodiesterase Inhibitors; Potassium Channels; Potassium Channels, Calcium-Activated; Proteins; Receptors, Parathyroid Hormone; Swine; Trachea | 1997 |
Effects of various selective phosphodiesterase inhibitors on muscle contractility in guinea pig ileal longitudinal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Detergents; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Octoxynol; Phosphodiesterase Inhibitors; Potassium; Purinones; Type C Phospholipases; Vasodilator Agents | 1997 |
Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells.
Topics: 1-Methyl-3-isobutylxanthine; Calcium; Calcium Channels; Carbachol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Humans; Inositol 1,4,5-Trisphosphate Receptors; Neuroblastoma; Neuropeptides; Peptide Fragments; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1998 |
Capacitative Ca2+ entry is involved in cAMP synthesis in mouse parotid acini.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels; Carbachol; Cell Compartmentation; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Ionomycin; Ionophores; Isoenzymes; Isoproterenol; Lanthanum; Mice; Muscarinic Agonists; Parotid Gland; Phosphodiesterase Inhibitors; Thapsigargin | 1998 |
Nitric oxide relaxes bovine ciliary muscle contracted by carbachol through elevation of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Cattle; Ciliary Body; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Indicators and Reagents; Methylene Blue; Miotics; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside | 1998 |
Effect of cAMP- and cGMP-related drugs on porcine cultured ciliary muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antihypertensive Agents; Bucladesine; Carbachol; Cells, Cultured; Ciliary Body; Colforsin; Cyclic AMP; Cyclic GMP; Immunoenzyme Techniques; Intraocular Pressure; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Nitroprusside; Phosphodiesterase Inhibitors; Swine | 1998 |
GLP-1 action in L6 myotubes is via a receptor different from the pancreatic GLP-1 receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cell Line; Cloning, Molecular; Cyclic AMP; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glycogen; Glycolysis; Insulin; Kinetics; Muscle, Skeletal; Pancreas; Peptide Fragments; Protein Precursors; Rats; Receptors, Glucagon; Recombinant Proteins; Transfection; Venoms | 1998 |
Helicobacter pylori fatty acid cis 9,10-methyleneoctadecanoic acid increases [Ca2+]i, activates protein kinase C and stimulates acid secretion in parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Calcium Signaling; Carbachol; Diglycerides; Enzyme Activation; Fatty Acids; Gastric Acid; Guinea Pigs; Helicobacter pylori; Histamine; L-Lactate Dehydrogenase; Parietal Cells, Gastric; Phosphatidylserines; Phosphodiesterase Inhibitors; Protein Kinase C; Staurosporine | 1998 |
Modulation by nitric oxide of gastric acid secretion in toads.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bufo marinus; Carbachol; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Parasympathomimetics; Parietal Cells, Gastric; Pentagastrin; Phosphodiesterase Inhibitors; Protons | 1998 |
Identification and functional importance of IL-1 receptors on rat parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Carbachol; Cell Separation; Cells, Cultured; Cyclic AMP; DNA Primers; Female; Histamine; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Parietal Cells, Gastric; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins | 1998 |
Characteristics of amylase secretion induced by various secretagogues examined in perifused rat parotid acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Bucladesine; Calcium; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Epithelial Cells; Isoproterenol; Male; Norepinephrine; Parasympatholytics; Parotid Gland; Rats; Rats, Wistar; Substance P; Sympathomimetics; Temperature | 1998 |
Gastric acid secretion is augmented by the replacement of extracellular Na+ with K+ or other ions.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Atropine; Bucladesine; Calcium; Carbachol; Carcinogens; Cations; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; In Vitro Techniques; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Omeprazole; Potassium; Rabbits; Rotenone; Sodium; Stomach; Tetradecanoylphorbol Acetate; Uncoupling Agents; Vagus Nerve | 1998 |
Gastrectomy induces impaired insulin and glucagon secretion: evidence for a gastro-insular axis in mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Colforsin; Cyclic AMP; Fasting; Female; Food Deprivation; Gastrectomy; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Parietal Cells, Gastric; Rats; Stomach; Tissue Extracts; Vagotomy | 1999 |
Relaxation of contracted rabbit tracheal and human bronchial smooth muscle by Y-27632 through inhibition of Ca2+ sensitization.
Topics: 1-Methyl-3-isobutylxanthine; Amides; Animals; Bronchi; Calcium; Carbachol; Cholinergic Agents; Detergents; Dose-Response Relationship, Drug; Endothelin-1; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intracellular Signaling Peptides and Proteins; Marine Toxins; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Octoxynol; Oxazoles; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Signal Transduction; Trachea; Type C Phospholipases | 1999 |
Elevated cAMP suppresses muscarinic inhibition of L-type calcium current in guinea pig ventricular myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cyclic AMP; Cyclic GMP; Guinea Pigs; Muscarinic Agonists; Okadaic Acid; Phosphoprotein Phosphatases | 1999 |
The cyclic AMP-protein kinase A pathway restrains islet phospholipase A(2) activation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium; Carbachol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Melitten; Peptide Fragments; Phospholipases A; Protein Precursors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sincalide; Vasoactive Intestinal Peptide | 2000 |
The secretory response of the rat colon to the flavonol quercetin is dependent on Ca2+-calmodulin.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Calmodulin; Carbachol; Chlorides; Colforsin; Colon; Diffusion Chambers, Culture; Indicators and Reagents; Intestinal Mucosa; Male; Muscarinic Agonists; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quercetin; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 2000 |
Influenza virus inhibits amiloride-sensitive Na+ channels in respiratory epithelia.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Carbachol; Cell Membrane; Cells, Cultured; Chickens; Colforsin; Hemagglutination Tests; Influenza A virus; Intestinal Mucosa; Kidney Cortex; Kidney Tubules, Collecting; Mice; Respiratory Mucosa; Sodium Channels; Trachea; Virulence Factors, Bordetella | 2000 |
Investigation of gastroprotective compounds at subcellular level in isolated gastric mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; 16,16-Dimethylprostaglandin E2; Animals; Arginine; Atropine; Carbachol; Catechols; Cell Membrane; Cell Nucleus; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Ethanol; Gastric Mucosa; Gastrointestinal Agents; Histamine; Mitochondria; Morpholines; Pentanones; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 2000 |
Cloning and function of the rat colonic epithelial K+ channel KVLQT1.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Barium; Carbachol; Cardiotonic Agents; Cloning, Molecular; Colforsin; Colon; Cyclic AMP; Dinoprostone; Humans; In Vitro Techniques; Intestinal Mucosa; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Male; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Tetraethylammonium; Xenopus laevis | 2001 |
Mechanism for muscarinic inhibition of I(Ca(L)) is determined by the path for elevating cyclic AMP in cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Atrial Natriuretic Factor; Calcium Channels, L-Type; Carbachol; Cyclic AMP; Enzyme Inhibitors; Guinea Pigs; Molsidomine; Muscarinic Agonists; Myocardium; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Second Messenger Systems | 2001 |
Regulation of slowly activating potassium current (I(Ks)) by secretin in rat pancreatic acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Calcium Signaling; Carbachol; Chlorides; Cholinergic Agonists; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gastrointestinal Agents; Isoproterenol; Isoquinolines; Membrane Potentials; Pancreas; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels; Rats; Secretin; Sulfonamides; Vasoactive Intestinal Peptide | 2001 |
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Dietary Fats; Drug Synergism; Fasting; Glucose; Glucose Tolerance Test; Homeostasis; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Palmitic Acid; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2001 |
Stimulation of chloride secretion by baicalein in isolated rat distal colon.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Atropine; Calcium; Carbachol; Chlorides; Colforsin; Colon; Cyclic AMP; Dinoprostone; Electric Conductivity; Female; Flavanones; Flavonoids; Indomethacin; Intestinal Mucosa; Male; Muscarinic Antagonists; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Thapsigargin | 2002 |
Disturbances of colonic ion secretion in inflammation: role of the enteric nervous system and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Biological Transport; Carbachol; Cholinergic Agonists; Colitis; Colon; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enteric Nervous System; Female; Gene Expression; Intestinal Mucosa; Ions; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Tetrodotoxin; Trinitrobenzenesulfonic Acid | 2002 |
Islet amyloid polypeptide inhibits glucagon release and exerts a dual action on insulin release from isolated islets.
Topics: 1-Methyl-3-isobutylxanthine; Amyloid; Animals; Arginine; Carbachol; Cholinergic Agonists; Culture Media; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Mice; Phosphodiesterase Inhibitors | 2003 |
Cyclic AMP compartmentation due to increased cAMP-phosphodiesterase activity in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8).
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Carbachol; Cell Compartmentation; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Electric Conductivity; Gene Expression; Heart; Humans; Isoproterenol; Mice; Mice, Transgenic; Muscarinic Agonists; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphodiesterase Inhibitors | 2003 |
Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blood Glucose; Carbachol; Dose-Response Relationship, Drug; Female; Ghrelin; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Pancreas; Peptide Hormones; Signal Transduction; Time Factors | 2004 |
Cholinergic-adrenergic antagonism in the induction of tachyarrhythmia by electrical stimulation in isolated rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Amiodarone; Animals; Anti-Arrhythmia Agents; Carbachol; Cholinergic Agonists; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Heart Atria; Male; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Muscarinic; Sodium Fluoride; Tachycardia; Time Factors | 2004 |
Muscarinic cholinergic regulation of L-type calcium channel in heart of embryonic mice at different developmental stages.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels, L-Type; Carbachol; Colforsin; Female; Heart; Mice; Muscarinic Agonists; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphodiesterase Inhibitors | 2004 |
Pretreatment with muscarinic receptor agonist activates a calcium-inhibitable adenylate cyclase in GH3 pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Biological Transport; Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Kinetics; Lanthanum; Muscarinic Antagonists; Pituitary Gland; Rats; Receptors, Muscarinic | 2005 |
Experimental inflammation of the rat distal colon inhibits ion secretion in the proximal colon by affecting the enteric nervous system.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cholinergic Agonists; Colon; Colonic Diseases; Female; Glutathione; Histamine; Inflammation; Patch-Clamp Techniques; Peroxidase; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 2005 |
Increased oxygen consumption caused by cAMP- and Ca(2+)-mediated chloride secretion in rat distal colon.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Chlorides; Colon; Cyclic AMP; Drug Interactions; Intestinal Mucosa; Male; Muscarinic Agonists; Oxygen Consumption; Rats; Rats, Wistar; Serotonin | 2005 |
Segmental heterogeneity of electrogenic secretions in human ascending colon and rectum.
Topics: 1-Methyl-3-isobutylxanthine; Carbachol; Chloride Channels; Colforsin; Colon; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprostone; Electrophoresis, Agar Gel; Electrophysiology; Humans; Intestinal Mucosa; Ion Transport; KCNQ1 Potassium Channel; Rectum; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Cellular mechanisms of carbachol-stimulated Cl- secretion in rat epididymal epithelium.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Carbachol; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Epididymis; Epithelial Cells; Epithelium; Imines; Male; Muscarinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Signal Transduction | 2006 |
Ultrastructural comparison of developing mouse embryonic stem cell- and in vivo-derived cardiomyocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Biomarkers; Calcium Channel Agonists; Calcium Channel Blockers; Carbachol; Cardiotonic Agents; Cell Differentiation; Cells, Cultured; Diltiazem; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Phenylephrine; Phosphodiesterase Inhibitors; Propranolol; Time Factors | 2006 |
Azithromycin has a direct relaxant effect on precontracted airway smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Bacterial Agents; Atropine; Azithromycin; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Enzyme Inhibitors; Epithelium; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Ouabain; Phosphodiesterase Inhibitors; Potassium Chloride; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Trachea; Verapamil | 2006 |
Identification of new small molecule inhibitors of cystic fibrosis transmembrane conductance regulator protein: in vitro and in vivo studies.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Apigenin; Bucladesine; Carbachol; Cell Line, Tumor; Chloride Channels; Cholera Toxin; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Intestines; Jejunum; Luminescent Proteins; Mice; Mice, Inbred ICR; Molecular Structure; Phosphodiesterase Inhibitors; Rats; Sulfonamides; Tetrahydronaphthalenes; Thiazoles | 2007 |
Modulatory role of phosphoinositide 3-kinase in gastric acid secretion.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Androstadienes; Animals; Carbachol; Cell Shape; Cells, Cultured; Cholinergic Agonists; Chromones; Cyclic AMP; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Morpholines; Mutation; Organ Culture Techniques; Parietal Cells, Gastric; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidinones; Rabbits; Receptors, Histamine H2; Signal Transduction; Time Factors; Transduction, Genetic; Wortmannin | 2007 |
Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in rat lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Blotting, Western; Calcium; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Cyclic CMP; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; In Vitro Techniques; Lacrimal Apparatus; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peroxidases; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Vasoactive Intestinal Peptide | 2007 |
Suppression of carbachol-induced oscillatory Cl- secretion by forskolin in rat parotid and submandibular acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antiporters; Carbachol; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Gramicidin; Male; Muscarinic Agonists; Parotid Gland; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Submandibular Gland | 2008 |
Beta cell chromogranin B is partially segregated in distinct granules and can be released separately from insulin in response to stimulation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cell Line; Cell Line, Tumor; Chromogranin B; Colforsin; Cytoplasmic Granules; Enzyme-Linked Immunosorbent Assay; Glucose; Image Processing, Computer-Assisted; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ionomycin; Microscopy, Immunoelectron; Rats | 2008 |
Strain-dependent differences in electrogenic secretion of electrolytes across mouse colon epithelium.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Barium; Bumetanide; Carbachol; Colforsin; Colon; Cyclic AMP; Electrolytes; Feces; Histamine; Histamine Antagonists; Intestinal Mucosa; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Muscarinic Antagonists; Potassium; Receptors, Histamine H1; Receptors, Muscarinic; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Water | 2010 |
Taurine supplementation: involvement of cholinergic/phospholipase C and protein kinase A pathways in potentiation of insulin secretion and Ca2+ handling in mouse pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dietary Supplements; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Phorbol Esters; Phospholipase C beta; Protein Kinase C-alpha; Taurine | 2010 |
The role of rectal chloride secretion in childhood constipation.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Biopsy; Carbachol; Child; Chlorides; Cholinergic Agonists; Colforsin; Constipation; Cystic Fibrosis Transmembrane Conductance Regulator; Defecation; Female; Hirschsprung Disease; Histamine; Histamine Agonists; Humans; Male; Phosphodiesterase Inhibitors; Rectum; Sodium Channel Blockers | 2011 |
Neurotransmitter influence on human meibomian gland epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Calcium; Carbachol; Cell Division; Cell Line, Transformed; Cholinergic Agonists; Colforsin; Epithelial Cells; Humans; Meibomian Glands; Parasympathetic Fibers, Postganglionic; Phosphodiesterase Inhibitors; Receptors, Muscarinic; Vasoactive Intestinal Peptide | 2011 |
Measurements of CFTR-mediated Cl- secretion in human rectal biopsies constitute a robust biomarker for Cystic Fibrosis diagnosis and prognosis.
Topics: 1-Methyl-3-isobutylxanthine; Biomarkers; Biopsy; Carbachol; Chlorides; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Humans; Ion Channel Gating; Prognosis; Rectum; Treatment Outcome | 2012 |
In vitro characterization of acid secretion in the gilthead sea bream (Sparus aurata) stomach.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Colforsin; Cyclic AMP; Electric Impedance; Gadolinium; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Macrolides; Muscarinic Agonists; Omeprazole; Proton Pump Inhibitors; Receptors, Calcium-Sensing; Sea Bream | 2014 |
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP; Diet, High-Fat; Disease Models, Animal; Glucose; Hyperglycemia; Hyperinsulinism; Hypertriglyceridemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Obesity; Rats; Rats, Wistar; Tissue Culture Techniques; Vagotomy; Vagus Nerve | 2016 |
Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Animals; Carbachol; Chlorogenic Acid; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice, Inbred Strains; Muscle Contraction; Muscle Relaxation; Phosphodiesterase 4 Inhibitors; Urinary Bladder | 2018 |