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carbachol and (4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride

carbachol has been researched along with (4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (18.84)	18.7374
1990's	44 (63.77)	18.2507
2000's	8 (11.59)	29.6817
2010's	4 (5.80)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bymaster, FP; Honoré, T; Mitch, CH; Nielsen, S; Olesen, PH; Pike, AJ; Sauerberg, P; Sheardown, MJ; Treppendahl, S; Ward, JS	1
Bøgesø, KP; Frederiksen, K; Løve Lembøl, H; Meier, E; Moltzen, EK; Pedersen, H; Sánchez, C	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barocelli, E; Bertoni, S; Bruni, B; Del Bello, F; Di Vaira, M; Giannella, M; Matucci, R; Nesi, M; Piergentili, A; Pigini, M; Quaglia, W	1
Barocelli, E; Bertoni, S; Bonifazi, A; Del Bello, F; Matucci, R; Mazzolari, A; Nesi, M; Piergentili, A; Quaglia, W; Vistoli, G	1
Sastry, BV; Stephan, CC	1
Mathes, C; Thompson, SH; Vargas, HM; Wang, SS	1
Fujiwara, M; Ishida, Y; Mizukami, M; Satake, N; Shibata, S; Taniguchi, T	1
Gies, JP; Haddad, EB; Landry, Y	1
Richards, MH	1
Daniel, EE; Janssen, LJ	1
el-Fakahany, EE; Hu, JR	1
Choo, LK; Mitchelson, F	1
Lai, J; Mei, L; Roeske, WR; Yamamura, HI	1
Matsumoto, K; Pappano, AJ	1
Choo, LK; Darroch, SA; Gardner, A; Mitchelson, F; Vong, YM	1
el-Fakahany, EE; Hu, J; Wang, SZ	1
Cost, M; Majewski, H	1
Donoff, B; Lad, R; Rangachari, PK	1
Luthin, GR; Manning, DR; Matesic, DF	1
Aksoy, S; Gibson, VA; McKinney, M; Miller, JH; Nickelson, L	1
Alonso, MJ; Arribas, S; Balfagón, G; Marín, J; Salaices, M	1
Bartus, RT; Fisher, SK	1
Bass, P; Fox, DA	1
McKinney, M; Rubanyi, GM; Vanhoutte, PM	1
Eglen, RM; Kenny, BA; Michel, AD; Whiting, RL	1
Carey, HV; Cooke, HJ; Tien, XY; Wallace, LJ	1
Bradshaw, CM; Sheridan, RD; Szabadi, E	1
Kleveland, PM; Larsson, H; Waldum, HL	1
Bowker, P; Daniel, EE; Jury, J	1
Fertel, R; Hadjiconstantinou, M; Neff, NH; Qu, ZX	1
Eltze, M	2
Gil, DW; Wolfe, BB	1
Brown, JH; Goldstein, D; Masters, SB	1
Choo, LK; Mitchelson, F; Vong, YM	1
Mitchelson, F; Shen, A	1
Hackmiller, RC; Jumblatt, JE	1
Brasili, L; Malmusi, L; Paparelli, F; Piergentili, A; Quaglia, W; Tayebati, SK	1
Cereda, E; Ladinsky, H; Sagrada, A; Schiavi, GB	1
Challiss, RA; Chilvers, ER; Giembycz, MA; Nahorski, SR; Offer, GJ	1
Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS	1
Ally, A; Hara, Y; Murayama, S	1
el-Fakahany, EE; Wang, SZ	1
Marks, GA; Roffwarg, HP	1
Barg, J; Fisher, A; Heldman, E; Kushnir, M; Levy, R; Pittel, Z; Vogel, Z; Zimlichman, R	1
Brann, MR; Bräuner-Osborne, H; Ebert, B; Falch, E; Krogsgaard-Larsen, P	1
Levin, RJ; Przyborski, SA	1
Hishinuma, S; Hongo, I; Kurokawa, M; Matsumoto, Y; Narita, F	1
Baba, H; Goldstein, PA; Kohno, T; Okamoto, M; Shimoji, K; Yoshimura, M	1
el-Fakahany, EE; Langason, RB; Wattenberg, EV; Wotta, DR	1
Dement, WC; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M	1
Beaucher, J; Harnois, C; Psarropoulou, C	1
Beck, M; Jánossy, A; Jurányi, Z; Orsó, E; Szalay, KS; Vinson, GP; Vizi, ES	1
Kojima, J; Onodera, K	1
Jaen, JC; Mirzadegan, T; Moreland, D; Schwarz, RD; Spencer, CJ; Tecle, H; Thomas, AJ	1
Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J	1
Akbulut, H; Akici, A; Karaalp, A; Oktay, S; Ulusoy, NB	1
Jiang, B; Pappano, AJ; Shen, JB	1
Acs, Z; Makara, GB; Némethy, Z	1
Ali, A; Börjesson, L; Delbro, DS; Nordgren, S	1
Feigl, EO; Hamilton, SE; Hardouin, SN; Nathanson, NM; Richmond, KN; Zimmerman, A	1
Goodchild, CS; Lograsso, M; Nadeson, R	1
Irie, Y; Kato, Y; Komori, S; Kwon, SC; Matsuyama, H; Okamoto, H; Unno, T	1
Hishinuma, S; Matsumoto, Y; Saito, M; Sato, R	1
Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S	1
Kitazawa, T; Komori, S; Kondo, T; Nakajima, M; Teraoka, H; Unno, T; Yamada, M	1
Anderson, RW; Strowbridge, BW	1
Antle, MC; Basu, P; Lefebvre, N; McKibbon, R; Wensel, AL	1

Other Studies

69 other study(ies) available for carbachol and (4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride

Article	Year
Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines . Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12 Topics: Animals; Atrial Function; Brain; Guinea Pigs; Heart Atria; Male; Molecular Structure; Myocardial Contraction; Parasympathomimetics; Pyridines; Rabbits; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Thiadiazoles	1992
Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity. Journal of medicinal chemistry, 1994, Nov-25, Volume: 37, Issue:24 Topics: Animals; Arecoline; Female; Guinea Pigs; Male; Mice; Rats; Rats, Wistar; Structure-Activity Relationship; Tetrazoles; Triazoles	1994
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation. Bioorganic & medicinal chemistry, 2009, Dec-15, Volume: 17, Issue:24 Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Dioxanes; Heart Atria; Humans; Male; Receptor, Muscarinic M3; Structure-Activity Relationship	2009
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites. Bioorganic & medicinal chemistry letters, 2014, Aug-01, Volume: 24, Issue:15 Topics: Animals; Binding Sites; Dioxanes; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Conformation; Muscarinic Agonists; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Structure-Activity Relationship	2014
Characterization of the subtype of muscarinic receptor coupled to the stimulation of phosphoinositide hydrolysis in 132-1N1 human astrocytoma cells. Cellular and molecular biology (Noisy-le-Grand, France), 1992, Volume: 38, Issue:7 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Astrocytoma; Atropine; Carbachol; Diamines; Humans; Hydrolysis; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Tumor Cells, Cultured	1992
Intracellular calcium release in N1E-115 neuroblastoma cells is mediated by the M1 muscarinic receptor subtype and is antagonized by McN-A-343. Brain research, 1992, Jul-10, Volume: 585, Issue:1-2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Calcium; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, Drug; Intracellular Membranes; Muscarinic Antagonists; Neuroblastoma; Parasympathomimetics; Receptors, Muscarinic; Tumor Cells, Cultured	1992
Anticholinergic action of disopyramide in intestinal smooth muscle of the guinea pig: inhibition of muscarinic receptors (M1 and M2). Japanese journal of pharmacology, 1990, Volume: 52, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Binding, Competitive; Carbachol; Cecum; Disopyramide; Guinea Pigs; Heart; Histamine; Ileum; In Vitro Techniques; Intestines; Male; Muscle, Smooth; Parasympatholytics; Quinuclidinyl Benzilate; Receptors, Muscarinic	1990
Sialic acid residues as catalysts for M2-muscarinic agonist-receptor interactions. Molecular pharmacology, 1990, Volume: 37, Issue:5 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cell Membrane; Kinetics; Male; Myocardium; Neuraminidase; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Sialic Acids	1990
Rat hippocampal muscarinic autoreceptors are similar to the M2 (cardiac) subtype: comparison with hippocampal M1, atrial M2 and ileal M3 receptors. British journal of pharmacology, 1990, Volume: 99, Issue:4 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Electric Stimulation; Hippocampus; Ileum; Inositol Phosphates; Male; Myocardium; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synapses	1990
Pre- and postjunctional muscarinic receptors in canine bronchi. The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic	1990
Selectivity of McN-A-343 in stimulating phosphoinositide hydrolysis mediated by M1 muscarinic receptors. Molecular pharmacology, 1990, Volume: 38, Issue:6 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Alkylation; Animals; Carbachol; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; GTP-Binding Proteins; Hydrolysis; Phosphatidylinositols; Receptors, Muscarinic	1990
Selective inhibition of responses to carbachol and McN-A-343 in the rabbit vas deferens. Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:9 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bis-Trimethylammonium Compounds; Carbachol; Cocaine; Electric Stimulation; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pancuronium; Pirenzepine; Rabbits; Vas Deferens	1990
Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82). The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Fibroblasts; Humans; Mice; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Muscarinic; Transfection	1991
Carbachol activates a novel sodium current in isolated guinea pig ventricular myocytes via M2 muscarinic receptors. Molecular pharmacology, 1991, Volume: 39, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cells, Cultured; Electric Conductivity; GTP-Binding Proteins; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Pertussis Toxin; Pirenzepine; Receptors, Muscarinic; Sodium; Virulence Factors, Bordetella	1991
Effect of temperature reduction on responsiveness to cholinomimetics in the taenia caeci of the guinea-pig. Journal of autonomic pharmacology, 1991, Volume: 11, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Colon; Drug Interactions; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Kinetics; Muscle Contraction; Parasympathomimetics; Phenoxybenzamine; Pirenzepine; Propylbenzilylcholine Mustard; Quinuclidinyl Benzilate; Temperature	1991
Effects of agonist efficacy on desensitization of phosphoinositide hydrolysis mediated by m1 and m3 muscarinic receptors expressed in Chinese hamster ovary cells. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cell Line; Cricetinae; Cricetulus; Down-Regulation; Female; Hydrolysis; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1991
Evidence for facilitatory and inhibitory muscarinic receptors on postganglionic sympathetic nerves in mouse isolated atria. British journal of pharmacology, 1991, Volume: 102, Issue:4 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cocaine; Diamines; Dicyclomine; Female; Heart; Hexamethonium Compounds; In Vitro Techniques; Mice; Myocardium; Nerve Endings; Neurons; Norepinephrine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Sympathetic Nervous System; Synaptic Transmission	1991
Functional subtyping of muscarinic receptors on canine esophageal mucosa. The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Amiloride; Animals; Atropine; Carbachol; Chlorides; Dogs; Electric Conductivity; Esophagus; Female; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mucous Membrane; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Sodium	1991
Tissue-dependent association of muscarinic acetylcholine receptors with guanine nucleotide-binding regulatory proteins. Molecular pharmacology, 1991, Volume: 40, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cerebellum; GTP-Binding Proteins; Myocardium; Rabbits; Rats; Receptors, Muscarinic	1991
Interactions of agonists with M2 and M4 muscarinic receptor subtypes mediating cyclic AMP inhibition. Molecular pharmacology, 1991, Volume: 40, Issue:6 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arecoline; Bethanechol; Bethanechol Compounds; Carbachol; Cells, Cultured; CHO Cells; Corpus Striatum; Cricetinae; Cyclic AMP; Kinetics; Male; Muscarine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic	1991
Presynaptic M2-muscarinic receptors on noradrenergic nerve endings and endothelium-derived M3 receptors in cat cerebral arteries. Brain research, 1991, Dec-13, Volume: 567, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Carbachol; Cats; Cerebral Arteries; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasodilation	1991
Regional differences in the coupling of muscarinic receptors to inositol phospholipid hydrolysis in guinea pig brain. Journal of neurochemistry, 1985, Volume: 45, Issue:4 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Brain; Carbachol; Corpus Striatum; Guinea Pigs; Hydrolysis; Oxotremorine; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Time Factors; Tissue Distribution	1985
Pharmacological characterization of rat jejunal contractility after chronic ablation of the myenteric plexus. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Barium; Barium Compounds; Benzalkonium Compounds; Carbachol; Chlorides; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Jejunum; Muscle Contraction; Myenteric Plexus; Physostigmine; Rats; Serous Membrane; Tetrodotoxin; Time Factors	1986
Biphasic release of endothelium-derived relaxing factor(s) by acetylcholine from perfused canine femoral arteries. Characterization of muscarinic receptors. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Carbachol; Dogs; Endothelium; Female; Femoral Artery; In Vitro Techniques; Male; Nitric Oxide; Pirenzepine; Receptors, Muscarinic; Vasodilator Agents	1987
Muscarinic activity of McN-A-343 and its value in muscarinic receptor classification. British journal of pharmacology, 1987, Volume: 90, Issue:4 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Male; Myocardium; N-Methylscopolamine; Parasympatholytics; Quaternary Ammonium Compounds; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1987
Muscarinic receptor subtypes mediating the mucosal response to neural stimulation of guinea pig ileum. The American journal of physiology, 1987, Volume: 253, Issue:3 Pt 1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Electric Conductivity; Electric Stimulation; Guinea Pigs; Ileum; Intestinal Mucosa; Male; Neurons; Parasympathomimetics; Quinuclidinyl Benzilate; Receptors, Muscarinic	1987
Involvement of M1-muscarinic receptors in the excitation of neocortical neurones by acetylcholine. Neuropharmacology, 1987, Volume: 26, Issue:8 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Carbachol; Cerebral Cortex; Male; Neurons; Nicotine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Time Factors	1987
Gastric acid secretion in the totally isolated, vascularly perfused rat stomach. A selective muscarinic-1 agent does, whereas gastrin does not, augment maximal histamine-stimulated acid secretion. Scandinavian journal of gastroenterology, 1987, Volume: 22, Issue:6 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Dose-Response Relationship, Drug; Gastric Acid; Gastrins; Histamine; Imidazoles; Impromidine; Male; Perfusion; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Secretory Rate; Stomach	1987
Muscarinic receptors on nerves and muscles in opossum esophagus muscularis mucosa. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:9 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Electric Stimulation; Esophagus; In Vitro Techniques; Mucous Membrane; Muscle Contraction; Muscle, Smooth; Neurons; Opossums; Parasympatholytics; Pirenzepine; Receptors, Muscarinic	1987
Pharmacological characterization of muscarinic receptors mediating inhibition of adenylate cyclase activity in the rat retina. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Arecoline; Aziridines; Carbachol; Choline; Colforsin; Cyclic AMP; Male; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Retina	1988
Assessment of selectivity of muscarinic antagonists for M1 and M2 receptors in rabbit isolated vas deferens. Pharmacology, 1988, Volume: 37 Suppl 1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atrial Function; Carbachol; Electric Stimulation; Heart Atria; In Vitro Techniques; Male; Muscle Contraction; Parasympatholytics; Rabbits; Receptors, Muscarinic; Vas Deferens	1988
Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Atropine; Benzodiazepinones; Brain; Carbachol; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Myocardium; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic	1985
The putative M1 muscarinic receptor does not regulate phosphoinositide hydrolysis. Studies with pirenzepine and McN-A343 in chick heart and astrocytoma cells. Molecular pharmacology, 1985, Volume: 27, Issue:5 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Astrocytoma; Benzodiazepinones; Carbachol; Cells, Cultured; Chick Embryo; Hydrolysis; Myocardium; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Pyrrolidines; Quaternary Ammonium Compounds; Receptors, Muscarinic	1985
The interaction of McN-A-343 with pirenzepine and other selective muscarine receptor antagonists at a prejunctional muscarine receptor. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 328, Issue:4 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Alkaloids; Animals; Atropine; Benzodiazepinones; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Pancuronium; Pirenzepine; Quaternary Ammonium Compounds; Rabbits; Receptors, Muscarinic	1985
Characterization of the muscarine receptor subtype on sympathetic nerve endings in the rat caudal artery. European journal of pharmacology, 1994, Feb-03, Volume: 252, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arteries; Atropine; Bis-Trimethylammonium Compounds; Carbachol; Female; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle, Smooth, Vascular; Nerve Endings; Parasympatholytics; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Sympathetic Nervous System; Tail; Trihexyphenidyl	1994
M2-type muscarinic receptors mediate prejunctional inhibition of norepinephrine release in the human iris-ciliary body. Experimental eye research, 1994, Volume: 58, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Child; Ciliary Body; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Middle Aged; Muscarine; Norepinephrine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic	1994
Synthesis and muscarinic receptors affinity of a series of antagonist bivalent ligands. Farmaco (Societa chimica italiana : 1989), 1994, Volume: 49, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atrial Function; Carbachol; Dioxolanes; Electric Stimulation; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Isometric Contraction; Ligands; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Rabbits; Receptors, Muscarinic; Vas Deferens	1994
Pathways involved in muscarinic M1 and M2 receptor stimulation in rabbit vas deferens. European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenylyl Cyclase Inhibitors; Animals; Carbachol; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Lithium Chloride; Male; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Phosphatidylinositols; Rabbits; Receptors, Muscarinic; Signal Transduction; Stereoisomerism; Tetradecanoylphorbol Acetate; Vas Deferens	1994
Antagonistic properties of McNeil-A-343 at 5-HT4 and 5-HT3 receptors. British journal of pharmacology, 1994, Volume: 113, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists	1994
Effect of temperature on muscarinic cholinoceptor-mediated phosphoinositide metabolism and tension generation in bovine tracheal smooth muscle. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:6 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cattle; Cold Temperature; Hydrolysis; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Receptors, Muscarinic; Time Factors; Trachea	1994
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle. British journal of pharmacology, 1995, Volume: 114, Issue:4 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic	1995
Cardiovascular effects of central administration of cholinomimetics in anesthetized cats. Neuropharmacology, 1993, Volume: 32, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Administration, Topical; Anesthesia; Animals; Blood Pressure; Carbachol; Cats; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Injections, Intraventricular; Kidney; Male; Medulla Oblongata; Parasympathomimetics; Physostigmine; Receptors, Muscarinic; Stereotaxic Techniques	1993
Application of transfected cell lines in studies of functional receptor subtype selectivity of muscarinic agonists. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Hydrolysis; N-Methylscopolamine; Phosphatidylinositols; Pilocarpine; Receptors, Muscarinic; Scopolamine Derivatives; Stimulation, Chemical; Substrate Specificity; Transfection	1993
Cholinergic responsiveness of neurons in the ventroposterior thalamus of the anesthetized rat. Neuroscience, 1993, Volume: 54, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Anesthesia, General; Animals; Carbachol; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hypothalamus, Posterior; Iontophoresis; Male; Neurons; Parasympatholytics; Pirenzepine; Rats; Stereotaxic Techniques	1993
Pharmacological basis for functional selectivity of partial muscarinic receptor agonists. European journal of pharmacology, 1996, Feb-22, Volume: 297, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Carbachol; CHO Cells; Cricetinae; Humans; Hydrolysis; Muscarinic Agonists; Oxotremorine; Phosphatidylinositols; Receptors, Muscarinic; Signal Transduction	1996
Functional partial agonism at cloned human muscarinic acetylcholine receptors. European journal of pharmacology, 1996, Oct-10, Volume: 313, Issue:1-2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Atropine; Binding, Competitive; Carbachol; Cells, Cultured; Cloning, Molecular; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Muscarinic Agonists; Muscarinic Antagonists; Nicotinic Agonists; Pirenzepine; Receptors, Muscarinic	1996
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine. The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:7 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin	1997
Contrasting effects of carbachol, McN-A-343 and AHR-602 on Ca(2+)-mobilization and Ca(2+)-influx pathways in taenia caeci. British journal of pharmacology, 1997, Volume: 122, Issue:6 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Binding Sites; Calcium; Carbachol; Cell Membrane; Colon; Extracellular Space; Female; Guinea Pigs; In Vitro Techniques; Ion Transport; Male; Muscarinic Agonists; Propylbenzilylcholine Mustard; Pyrrolidines	1997
Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn. The Journal of physiology, 1998, Apr-01, Volume: 508 ( Pt 1) Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Diamines; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Muscarinic Agonists; Neostigmine; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin	1998
M1, M3 and M5 muscarinic receptors stimulate mitogen-activated protein kinase. Pharmacology, 1998, Volume: 56, Issue:4 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Androstadienes; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Muscarinic Agonists; Pertussis Toxin; Pilocarpine; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptor, Muscarinic M5; Receptors, Muscarinic; Serotonin Antagonists; Virulence Factors, Bordetella; Wortmannin	1998
Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines. Experimental neurology, 1998, Volume: 151, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Behavior, Animal; Carbachol; Cataplexy; Cholinergic Fibers; Dogs; Feeding Behavior; Female; GABA Agonists; Gallamine Triethiodide; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Muscimol; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Piperidines; Pirenzepine; Prosencephalon	1998
Comparison of the effects of M1 and M2 muscarinic receptor activation in the absence of GABAergic inhibition in immature rat hippocampal CA3 area. Brain research. Developmental brain research, 1998, May-15, Volume: 107, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bicuculline; Carbachol; Dose-Response Relationship, Drug; Epilepsy; Evoked Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Muscarinic Agonists; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic	1998
Cholinergic regulation of the rat adrenal zona glomerulosa. The Journal of endocrinology, 1998, Volume: 157, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Aldosterone; Animals; Atropine; Carbachol; Choline O-Acetyltransferase; Cholinergic Fibers; Histocytochemistry; Immunohistochemistry; Male; Microscopy, Immunoelectron; Muscarinic Agonists; Muscarinic Antagonists; Organ Culture Techniques; Pirenzepine; Rats; Rats, Sprague-Dawley; Zona Glomerulosa	1998
NIK-247 induces long-term potentiation of synaptic transmission in the CA1 region of rat hippocampal slices through M2 muscarinic receptors. General pharmacology, 1998, Volume: 31, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Aminoquinolines; Animals; Carbachol; Cholinesterase Inhibitors; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Physostigmine; Rats; Rats, Wistar; Receptors, Muscarinic; Synaptic Transmission; Tacrine	1998
Mutations of aspartate 103 in the Hm2 receptor and alterations in receptor binding properties of muscarinic agonists. Life sciences, 1995, Volume: 56, Issue:11-12 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Alanine; Amino Acid Substitution; Animals; Arecoline; Asparagine; Aspartic Acid; Carbachol; COS Cells; Muscarinic Agonists; Mutagenesis, Site-Directed; Oxotremorine; Pilocarpine; Receptor, Muscarinic M2; Receptors, Muscarinic; Transfection	1995
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro. Neuroscience, 1999, Volume: 90, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission	1999
Distinct functional muscarinic receptors in guinea-pig gallbladder, ileum and atria. Pharmacological research, 1999, Volume: 39, Issue:5 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Electric Stimulation; Female; Gallbladder; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Oxotremorine; Rats; Rats, Wistar; Receptors, Muscarinic	1999
Lack of effect of McN-A-343 on membrane current and contraction in guinea pig ventricular myocytes. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adrenergic beta-Agonists; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cell Membrane; Cyclic AMP; Electrophysiology; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Muscarinic Agonists; Myocardial Contraction; Oxotremorine; Patch-Clamp Techniques; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic	1999
Effect of cholinergic drugs on the concentration of intracellular free calcium of rat pituitary intermediate lobe cells. Brain research bulletin, 1999, Sep-01, Volume: 50, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Age Factors; Animals; Atropine; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Cytosol; Female; Male; Melanocytes; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar; Vasodilator Agents	1999
Relaxation of rat distal colon by activation of muscarinic, neuronal receptors: possible involvement of P(2y)-purinoceptors. Journal of the autonomic nervous system, 2000, Jul-03, Volume: 81, Issue:1-3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Colon; In Vitro Techniques; Lidocaine; Male; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Neurons; Potassium; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Second Messenger Systems	2000
Altered cardiovascular responses in mice lacking the M(1) muscarinic acetylcholine receptor. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Blotting, Southern; Carbachol; Ganglia, Sympathetic; Heart; Hemodynamics; Mice; Mice, Knockout; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositols; Precipitin Tests; Quinuclidinyl Benzilate; Receptor, Muscarinic M1; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stimulation, Chemical; Vagotomy	2002
The spinal antinociceptive effects of cholinergic drugs in rats: receptor subtype specificity in different nociceptive tests. BMC pharmacology, 2002, Nov-19, Volume: 2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cholinergic Agents; Disease Models, Animal; Male; Muscarinic Agonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptor, Muscarinic M1; Spinal Cord	2002
Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscle. British journal of pharmacology, 2003, Volume: 139, Issue:2 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Calcium; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Male; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pilocarpine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction	2003
Differential development of carbachol-induced desensitization in receptor-mediated Ca2+ influx and Ca2+ release pathways in smooth muscle of guinea-pig taenia caeci. Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Calcium; Calcium Signaling; Carbachol; Cecum; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Receptor Cross-Talk	2007
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection	2007
Muscarinic receptor subtypes involved in regulation of colonic motility in mice: functional studies using muscarinic receptor-deficient mice. European journal of pharmacology, 2011, Nov-16, Volume: 670, Issue:1 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Biomechanical Phenomena; Carbachol; Colon; Defecation; Female; Gastrointestinal Motility; Gene Knockout Techniques; In Vitro Techniques; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Pirenzepine; Receptors, Muscarinic	2011
Regulation of persistent activity in hippocampal mossy cells by inhibitory synaptic potentials. Learning & memory (Cold Spring Harbor, N.Y.), 2014, Apr-15, Volume: 21, Issue:5 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Animals, Newborn; Carbachol; Cholinergic Agonists; Electric Stimulation; Excitatory Amino Acid Agents; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Muscarinic Agonists; Muscarinic Antagonists; Nerve Fibers; Pirenzepine; Pyramidal Cells; Rats; Rats, Sprague-Dawley	2014
Activation of M1/4 receptors phase advances the hamster circadian clock during the day. Neuroscience letters, 2016, 05-16, Volume: 621 Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol; Carbachol; Cholinergic Agonists; Circadian Clocks; Male; Mesocricetus; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Suprachiasmatic Nucleus	2016