Page last updated: 2024-08-17

caramiphen and cyclopentane

caramiphen has been researched along with cyclopentane in 96 studies

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-199062 (64.58)18.7374
1990's14 (14.58)18.2507
2000's5 (5.21)29.6817
2010's14 (14.58)24.3611
2020's1 (1.04)2.80

Authors

AuthorsStudies
Chou, DT; Wallenstein, MC; Wang, SC1
Bak, W; Borkowska, G; Faff, J; Rump, S; Szymańska, T1
Baimbridge, KG; Church, J; Shacklock, JA1
Annels, SJ; Davies, JA; Ellis, Y1
DeHaven-Hudkins, DL; Hudkins, RL; Stubbins, JF2
Apland, JP; Braitman, DJ1
Braitman, DJ; Brennecke, LH; Sparenborg, S1
Musacchio, JM; Tortella, FC; Witkin, JM1
Yu, YX; Zhang, LM1
Domino, EF; Krutak-Krol, H; Lal, J1
Flanagan, T; Levandoski, P1
Grünthal, E2
Diana, G; Pezzola, A; Popoli, P; Sagratella, S; Scotti de Carolis, A1
Allen, JT; DeHaven-Hudkins, DL; Hudkins, RL; Stubbins, JF; Tortella, FC1
Katz, JL; Sharpe, LG; Székely, JI1
Domenici, MR; Frank, C; Sagratella, S; Scotti de Carolis, A1
Allen, JT; DeHaven-Hudkins, DL; Ford-Rice, FY; Hudkins, RL1
Baragatti, G; Dematteis, M; Gavend, M; Mallaret, M1
Alkalay, D; Chapman, S; Cohen, G; Gilat, E; Rabinovitz, I; Raveh, L; Weissman, BA1
Alkalay, D; Brandeis, R; Cohen, G; Rabinovitz, I; Raveh, L; Sonego, H; Weissman, BA1
SNYDER, GG1
GLICK, J1
BOYSEN, KH1
HORAUF, A; MECHELKE, K1
BEHREND, RC1
OTTLIK, H1
PULVER, R1
GOKAY, FK; TUKEL, K1
HERRLIN, KM; MELIN, KA1
ANDRIEU, B; DELGA, J1
CARTER, S; MERRITT, HH; SCIARRA, D1
SANYAL, RK1
LEIGH, D; SCHWAB, RS2
DE SCHAEPDRYVER, A1
JERSILD, T2
KAERCHER, W; MAURATH, J1
DROBEC, E; ZEIHSL, E1
MEIRSMAN-ROOBROECK, GC1
DIERCKS, AL1
PAKESCH, EF1
JORDAN, J; UIBERALL, E1
WINTHER, K1
Abraham, S; Cohen, G; Dachir, S; Gilat, E; Herskovitz, M; Kapon, J; Levy, A; Raveh, L; Teitelbaum, Z1
BORELLINI, A; DAVINI, V1
KOWALEWSKI, K; MAHAUX, J2
COBB, CT; LEIGH, D; SCHWAB, RS1
SCHWAB, RS; TILLMANN, WR1
DAENINCK, L; LIBBRECHT, L2
GRUBER, CM; KRAATZ, CP2
MUNCH-PETERSEN, S1
DALSGAARD-NIELSEN, T1
HERMANN, K1
Brandeis, R; Egoz, I; Gilat, E; Kapon, J; Rabinovitz, I; Raveh, L; Stavitsky, Z; Weissman, BA1
Aas, P; Enger, S; Myhrer, T2
Raveh, L; Weissman, BA2
BICKEL, G; DUBOIS, JP1
HEUSCHER, JE; SCHOELLY, ML1
JOACHIMOGLU, G; KLISSIUNIS, N1
BOOIJ, J1
HABERMANN, H1
POLICZER, M1
BAUD, C; FLEISCH, A1
LANINI, G; LEHNER, F1
DUNHAM, WF; EDWARDS, CH1
DE VLEESCHHOUWER, GR; HEYMANS, C3
FLEISCH, A; GRANDJEAN, E1
Chen, YC; Chen, YW; Chu, CC; Hung, CH; Wang, JJ1
HARTMANN, K2
MONAKOW, KH1
Honda, S; Kawaura, K; Shirasaki, T; Soeda, F; Takahama, K1
Honda, S; Kawaura, K; Miki, R; Shima, E; Shirasaki, T; Soeda, F; Takahama, K1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Ferrara, TM; Figueiredo, TH; Pidoplichko, V; Qashu, F; Stevens, D1
Aas, P; Enger, S; Jonassen, M; Myhrer, T1
Kelley, NR; Lee, RB; Lumley, LA; Moffett, MC; Schultz, MK; Schwartz, JE; Stone, MF; Wright, LK1
Bloch-Shilderman, E; Brandeis, R; Egoz, I; Grauer, E; Katalan, S; Lazar, S; Rabinovitz, I; Raveh, L1
Patil, SP1
Eisenkraft, A; Raveh, L; Weissman, BA1
Chen, YW; Gong, CL; Leung, YM; Tzeng, JI; Wang, JJ; Wang, YW1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MFM; Figueiredo, TH; Pidoplichko, VI; Rossetti, K1
Apland, JP; Aroniadou-Anderjaska, V; Braga, MFM; De Araujo Furtado, M; Figueiredo, TH2

Reviews

5 review(s) available for caramiphen and cyclopentane

ArticleYear
Discriminative stimulus properties of dextromethorphan in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1995, Volume: 49, Issue:10

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antitussive Agents; Cyclazocine; Cyclopentanes; Dextromethorphan; Dextrorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Morphine; Neuroprotective Agents; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, sigma

1995
Therapy against organophosphate poisoning: the importance of anticholinergic drugs with antiglutamatergic properties.
    Toxicology and applied pharmacology, 2008, Oct-15, Volume: 232, Issue:2

    Topics: Animals; Cholinergic Antagonists; Cholinesterase Inhibitors; Cyclopentanes; Excitatory Amino Acid Antagonists; Gas Poisoning; Glutamic Acid; Humans; Organophosphate Poisoning; Organophosphates

2008
[Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, Volume: 130, Issue:5

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Cyclopentanes; Disease Models, Animal; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Male; Piperidines; Rats; Rats, Wistar

2010
Multifunctional drugs as novel antidotes for organophosphates' poisoning.
    Toxicology, 2011, Dec-18, Volume: 290, Issue:2-3

    Topics: Acetylcholine; Animals; Antidotes; Atropine; Cholinergic Antagonists; Cyclopentanes; Excitatory Amino Acid Antagonists; Humans; Muscarinic Antagonists; Organophosphate Poisoning; Poisoning; Scopolamine

2011
Caramiphen edisylate: an optimal antidote against organophosphate poisoning.
    Toxicology, 2014, Nov-05, Volume: 325

    Topics: Acetylcholine; Animals; Antidotes; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cyclopentanes; Humans; Neuroprotective Agents; Organophosphate Poisoning

2014

Trials

1 trial(s) available for caramiphen and cyclopentane

ArticleYear
Caramiphen and scopolamine prevent soman-induced brain damage and cognitive dysfunction.
    Neurotoxicology, 2002, Volume: 23, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cognition Disorders; Cyclopentanes; Escape Reaction; Hypoxia, Brain; Male; Maze Learning; Prosencephalon; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Soman; Swimming

2002

Other Studies

90 other study(ies) available for caramiphen and cyclopentane

ArticleYear
Studies on the potency of various antitussive agents.
    Agents and actions, 1977, Volume: 7, Issue:3

    Topics: Animals; Antitussive Agents; Cats; Clonazepam; Codeine; Cough; Cyclopentanes; Dextromethorphan; Diazepam; Ethylamines; Injections, Intravenous

1977
Efficacy of repeated pharmacotherapy in experimental acute poisonings with fluostigmine.
    Archives of toxicology, 1976, Aug-18, Volume: 35, Issue:4

    Topics: Animals; Antidotes; Atropine; Cyclopentanes; Diazepam; Diethylamines; Isoflurophate; Obidoxime Chloride; Rats

1976
Dextromethorphan and phencyclidine receptor ligands: differential effects on K(+)- and NMDA-evoked increases in cytosolic free Ca2+ concentration.
    Neuroscience letters, 1991, Apr-01, Volume: 124, Issue:2

    Topics: Animals; Calcium; Cyclopentanes; Cytosol; Dextromethorphan; Female; Fura-2; Hippocampus; Ketamine; Ligands; N-Methylaspartate; Parasympatholytics; Potassium; Pregnancy; Pyramidal Tracts; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine

1991
Non-opioid antitussives inhibit endogenous glutamate release from rabbit hippocampal slices.
    Brain research, 1991, Nov-15, Volume: 564, Issue:2

    Topics: Animals; Antitussive Agents; Aspartic Acid; Cyclopentanes; Depression, Chemical; Dextromethorphan; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Potassium; Rabbits

1991
Muscarinic receptor binding profile of para-substituted caramiphen analogues.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:10

    Topics: Animals; Binding, Competitive; Cerebral Cortex; Cyclopentanes; Male; Molecular Structure; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship

1991
Effects of non-opioid antitussives on epileptiform activity and NMDA responses in hippocampal and olfactory cortex slices.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: Animals; Antitussive Agents; Cyclopentanes; Dextromethorphan; Electric Stimulation; Epilepsy; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; N-Methylaspartate; Olfactory Bulb

1990
Prevention of soman neurotoxicity by non-opioid antitussives.
    Neurotoxicology, 1990,Fall, Volume: 11, Issue:3

    Topics: Animals; Anticonvulsants; Antitussive Agents; Cyclopentanes; Dextromethorphan; Guinea Pigs; Male; Necrosis; Nervous System Diseases; Neurons; Soman

1990
Caramiphen: a non-opioid antitussive with potent anticonvulsant properties in rats.
    European journal of pharmacology, 1988, Oct-11, Volume: 155, Issue:1-2

    Topics: Animals; Anticonvulsants; Antitussive Agents; Atropine; Behavior, Animal; Cyclopentanes; Electroshock; Injections, Subcutaneous; Male; Phenytoin; Physostigmine; Rats; Rats, Inbred Strains; Time Factors

1988
[Studies on the fluorometric ion pair method for the determination of several tertiary amines].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:10

    Topics: Amines; Anthracenes; Benzoates; Benztropine; Cyclopentanes; Indicators and Reagents; Ions; Spectrometry, Fluorescence

1985
Evidence for a central site of action for the antitussive effects of caramiphen.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1

    Topics: Animals; Antitussive Agents; Brain Stem; Cats; Cough; Cyclopentanes; Decerebrate State; Dextromethorphan; Female

1985
Use of nitrogen-specific detector for GLC determination of caramiphen in whole blood.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:11

    Topics: Antitussive Agents; Chromatography, Gas; Cyclopentanes; Humans

1980
[Scientific raisins from 125 years SMW (Swiss Medical Weekly). On Parpanit, a new agents which modifies extrapyramidal motor disorders. 1946].
    Schweizerische medizinische Wochenschrift, 1995, Oct-14, Volume: 125, Issue:41

    Topics: Antiparkinson Agents; Basal Ganglia Diseases; Cyclopentanes; History, 20th Century; Humans

1995
Non-opioid antitussives potentiate some behavioural and EEG effects of N-methyl-D-aspartate channel blockers.
    Life sciences, 1993, Volume: 52, Issue:19

    Topics: Animals; Antitussive Agents; Behavior, Animal; Cyclopentanes; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Ion Channels; Male; Mice; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
Anticonvulsant activity of caramiphen analogs.
    Life sciences, 1995, Volume: 56, Issue:19

    Topics: Animals; Anticonvulsants; Cyclopentanes; Male; Pentazocine; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1995
Effects of caramiphen and phencyclidine alone and in combination on behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Animals; Ataxia; Behavior, Animal; Cyclopentanes; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Parasympatholytics; Phencyclidine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior

1994
Effects of non-opioid antitussives on hypoxia-induced electrical changes in rat hippocampal slices: a comparative study with anticonvulsant drugs.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Animals; Anticonvulsants; Antitussive Agents; Cyclopentanes; Dizocilpine Maleate; Electrophysiology; Epilepsy; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Membrane Potentials; Phenytoin; Rats; Rats, Wistar

1993
Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarinic M1 receptor-selective agents.
    European journal of pharmacology, 1993, Feb-16, Volume: 231, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Culture Techniques; Cyclopentanes; Male; Myocardium; Nitro Compounds; Parasympatholytics; Parasympathomimetics; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic

1993
Allosteric modulation of ligand binding to [3H](+)pentazocine-defined sigma recognition sites by phenytoin.
    Life sciences, 1993, Volume: 53, Issue:1

    Topics: Allosteric Regulation; Animals; Binding Sites; Cyclopentanes; Dextromethorphan; Dextrorphan; Guinea Pigs; Ligands; Male; Pentazocine; Phenazocine; Phenytoin; Piperidines; Radioligand Assay; Receptors, sigma; Tritium

1993
The involvement of the NMDA receptor complex in the protective effect of anticholinergic drugs against soman poisoning.
    Neurotoxicology, 1999, Volume: 20, Issue:4

    Topics: Animals; Brain; Cholinesterase Inhibitors; Cyclopentanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Flunitrazepam; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Parasympatholytics; Protein Binding; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Scopolamine; Seizures; Soman; Time Factors

1999
An evaluation of caramiphen ethane disulfonate as an antitussive agent.
    The Laryngoscope, 1953, Volume: 63, Issue:10

    Topics: Antitussive Agents; Cough; Cyclopentanes; Ethane

1953
CARAMIPHEN hydrochloride.
    Journal of the American Medical Association, 1959, Apr-25, Volume: 169, Issue:17

    Topics: Cyclopentanes; Parasympatholytics

1959
Codeine vs. caramiphen in cough control.
    Delaware medical journal, 1963, Volume: 35

    Topics: Codeine; Cough; Cyclopentanes; Humans; Parasympatholytics

1963
[Experiences with parpanit in the treatment of dyskinetic states].
    Medizinische Klinik, 1950, Sep-01, Volume: 45, Issue:35

    Topics: Cyclopentanes; Encephalitis

1950
[Cardiovascular effects of parpanit].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1950, Volume: 211, Issue:5

    Topics: Cardiovascular System; Cyclopentanes

1950
[Parpanit therapy of extrapyramidal disorders].
    Munchener medizinische Wochenschrift (1950), 1951, Jan-05, Volume: 93, Issue:1

    Topics: Basal Ganglia Diseases; Cyclopentanes; Parkinsonian Disorders

1951
[An experiment to record the effect of massive doses of parpanit on convulsion in electric shock].
    Der Nervenarzt, 1951, Mar-20, Volume: 22, Issue:3

    Topics: Convulsive Therapy; Cyclopentanes; Seizures

1951
[Resorption, decomposition and elimination of parpanit in the organism].
    Archives internationales de pharmacodynamie et de therapie, 1951, Apr-01, Volume: 86, Issue:2

    Topics: Biological Phenomena; Cyclopentanes; Humans; Physiological Phenomena

1951
[Parpanit in therapy of extrapyramidal diseases].
    Schweizerische medizinische Wochenschrift, 1951, Jun-16, Volume: 81, Issue:24

    Topics: Basal Ganglia Diseases; Cyclopentanes; Extrapyramidal Tracts; Humans

1951
[Parpanit and artane as pediatric antispasmodics].
    Nordisk medicin, 1952, Mar-07, Volume: 47, Issue:10

    Topics: Cardiovascular Agents; Cerebral Palsy; Cyclopentanes; Muscle Relaxants, Central; Parasympatholytics; Trihexyphenidyl

1952
[Some properties of diethylamino ethyl ester of phenylcyclopentane carbonic acid (parpanit); its destruction and its distribution in the organism].
    Therapie, 1951, Volume: 6, Issue:6

    Topics: Carbonic Acid; Cardiovascular Agents; Cyclopentanes; Muscle Relaxants, Central

1951
Caramiphen hydrochloride in the treatment of diseases of the basal ganglions.
    Journal of the American Medical Association, 1949, Dec-24, Volume: 141, Issue:17

    Topics: Basal Ganglia; Cyclopentanes; Ganglia; Ganglion Cysts; Humans

1949
A case of Parkinson's disease treated with parpanit.
    The Indian medical gazette, 1949, Volume: 84, Issue:8

    Topics: Cyclopentanes; Parkinson Disease; Parkinsonian Disorders

1949
[Parpanit in the treatment of Parkinson disease (transl)].
    Prensa medica argentina, 1949, Dec-09, Volume: 36, Issue:49

    Topics: Cyclopentanes; Parkinson Disease; Parkinsonian Disorders

1949
[Pharmacological action on the bronchi of the guinea pig].
    Archives internationales de pharmacodynamie et de therapie, 1950, Apr-15, Volume: 82, Issue:2

    Topics: Bronchi; Cyclopentanes; Guinea Pigs; Phenothiazines

1950
Congenital spastic paralysis treated with parpanit.
    Acta paediatrica, 1950, Volume: 39, Issue:1-2

    Topics: Cerebral Palsy; Cyclopentanes; Muscle Spasticity; Paralysis

1950
[Effect of parpanit on blood circulation].
    Archives internationales de pharmacodynamie et de therapie, 1950, May-15, Volume: 82, Issue:4

    Topics: Blood; Blood Vessels; Cyclopentanes

1950
[Treatment of spasticity and local muscular spasm with parpanit].
    Praxis, 1950, Jun-01, Volume: 39, Issue:22

    Topics: Central Nervous System; Cyclopentanes; Humans; Muscle Spasticity; Muscles; Spasm

1950
The protective action of parpanit, diparcol and some other drugs against chloroform-adrenaline ventricular fibrillation.
    Archives internationales de pharmacodynamie et de therapie, 1950, Aug-01, Volume: 83, Issue:3

    Topics: Arrhythmias, Cardiac; Chloroform; Cyclopentanes; Epinephrine; Humans; Phenothiazines; Ventricular Fibrillation

1950
[Experience with therapeutic use of parpanit].
    Nederlands tijdschrift voor geneeskunde, 1950, May-06, Volume: 94, Issue:18

    Topics: Cyclopentanes; Parkinsonian Disorders

1950
[Treatment of extrapyramidal motor disturbances].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1950, Volume: 31, Issue:6

    Topics: Cyclopentanes; Movement; Paralysis; Parkinsonian Disorders

1950
[Modern drugs in the treatment of parkinsonism and similar diseases].
    Revista medica de Chile, 1950, Volume: 78, Issue:7

    Topics: Cyclopentanes; Mephenesin; Paralysis; Parkinsonian Disorders; Phenothiazines

1950
[Treatment of paralysis agitans with some new preparations: parpanit, diparcol, and phenergan].
    Ugeskrift for laeger, 1950, May-25, Volume: 112, Issue:21

    Topics: Cyclopentanes; Histamine; Parkinson Disease; Parkinsonian Disorders; Phenothiazines; Promethazine

1950
Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning.
    Archives of toxicology, 2007, Volume: 81, Issue:5

    Topics: Animals; Chemical Warfare Agents; Cholinergic Antagonists; Cyclopentanes; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Infusions, Parenteral; Lethal Dose 50; Male; Metabolic Clearance Rate; Organophosphate Poisoning; Organophosphates; Papio anubis; Poisoning; Pyridostigmine Bromide; Sarin; Species Specificity; Treatment Outcome

2007
Observations on the effect of parpanit on motility disorders from extrapyramidal and pyramidal lesions.
    Minerva medica, 1948, Oct-27, Volume: 39, Issue:43 Pt 2

    Topics: Cyclopentanes; Humans; Parasympatholytics; Pharmaceutical Preparations

1948
Action of the diethylaminoethyl ester of phenyl-cyclopentane-carboxylic acid (parpanit) on basal metabolism and metabolism after the effort of hyperthyroid, hypothyroid and normothyroid subjects.
    Archives internationales de pharmacodynamie et de therapie, 1948, Sep-01, Volume: 77, Issue:3

    Topics: Basal Metabolism; Cyclopentanes

1948
Parpanit in the treatment of Parkinson's disease.
    Journal of the American Medical Association, 1949, Mar-05, Volume: 139, Issue:10

    Topics: Cyclopentanes; Humans; Parkinson Disease; Parkinsonian Disorders

1949
Treatment of Parkinson's disease with parpanit; a preliminary report.
    Transactions of the American Neurological Association, 1948, Volume: 73, Issue:73 Annual

    Topics: Cyclopentanes; Humans; Parkinson Disease; Parkinsonian Disorders

1948
Artane in the treatment of Parkinson's disease; a report of its effectiveness alone and in combination with benadryl and parpanit.
    The New England journal of medicine, 1949, Sep-29, Volume: 241, Issue:13

    Topics: Cyclopentanes; Diphenhydramine; Parkinson Disease; Parkinsonian Disorders; Trihexyphenidyl

1949
On the central action of the ethylamino-ethyl ester of phenyl-cyclopentane carboxylic acid, parpanit.
    Archives internationales de pharmacodynamie et de therapie, 1949, May-01, Volume: 79, Issue:2-3

    Topics: Cyclopentanes

1949
The effect of diethylaminoethyl ester of 1-phenylcyclopentane-1-carboxylic acid hydrochloride, parpanit, on decerebrate rigidity, spinal reflexes and skeletal muscle.
    The Journal of pharmacology and experimental therapeutics, 1949, Volume: 96, Issue:1

    Topics: Carboxylic Acids; Cyclopentanes; Decerebrate State; Muscle, Skeletal; Muscles; Reflex

1949
Pharmacologic and toxicologic studies on diethyl aminoethyl ester of 1-phenyl-cyclopentane-1-carboxylic acid hydrochloride, parpanit.
    The Journal of pharmacology and experimental therapeutics, 1949, Volume: 96, Issue:1

    Topics: Carboxylic Acids; Cyclopentanes; Esters

1949
About the preparation parpanite; used for 30 patients with Parkinsonism.
    Ugeskrift for laeger, 1949, Apr-21, Volume: 111, Issue:16

    Topics: Cyclopentanes; Encephalitis; Encephalitis, Arbovirus; Epidemics

1949
Parpanite treatment of paralysis agitans.
    Ugeskrift for laeger, 1949, Apr-21, Volume: 111, Issue:16

    Topics: Cyclopentanes; Encephalitis; Encephalitis, Arbovirus; Epidemics

1949
About parpanite; treatment results spec. by encephalitic parkinsonism.
    Ugeskrift for laeger, 1949, Apr-21, Volume: 111, Issue:16

    Topics: Cyclopentanes; Encephalitis; Encephalitis, Arbovirus; Epidemics

1949
Morbus Little treated with parpanite.
    Ugeskrift for laeger, 1949, Apr-21, Volume: 111, Issue:16

    Topics: Cyclopentanes

1949
Efficacy of antidotal treatment against sarin poisoning: the superiority of benactyzine and caramiphen.
    Toxicology and applied pharmacology, 2008, Feb-15, Volume: 227, Issue:1

    Topics: Animals; Antidotes; Behavior, Animal; Benactyzine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cyclopentanes; Male; Rats; Rats, Sprague-Dawley; Sarin

2008
Antiparkinson drugs used as prophylactics for nerve agents: studies of cognitive side effects in rats.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:4

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Benactyzine; Biperiden; Cholinergic Antagonists; Cholinesterase Inhibitors; Cognition; Cyclopentanes; Exploratory Behavior; Male; Motor Activity; Neurotoxins; Organophosphorus Compounds; Physostigmine; Procyclidine; Rats; Rats, Wistar; Trihexyphenidyl

2008
Parpanit in the treatment of intentional tremor; multiple sclerosis and upper red kernel syndrome.
    Revue medicale de la Suisse romande, 1947, Oct-25, Volume: 67, Issue:10

    Topics: Cyclopentanes; Humans; Multiple Sclerosis; Sclerosis; Tremor

1947
Contribution to the physiological effects of parpanit and curare based on self-experiments.
    Schweizerische medizinische Wochenschrift, 1948, May-29, Volume: 78, Issue:21

    Topics: Curare; Cyclopentanes

1948
Contribution to the pharmacology of Parpanit and some of its relatives.
    Schweizerische medizinische Wochenschrift, 1948, May-29, Volume: 78, Issue:21

    Topics: Cyclopentanes

1948
The treatment of Parkinson's syndrome with parpanite.
    Nederlands tijdschrift voor geneeskunde, 1948, Apr-03, Volume: 92, Issue:14

    Topics: Cyclopentanes; Parkinsonian Disorders

1948
Experience with the new preparation Parpanit in the treatment of diseases of the extrapyramidal motor system.
    Der Nervenarzt, 1948, Volume: 19, Issue:5

    Topics: Basal Ganglia Diseases; Cyclopentanes; Syndrome

1948
Central action of the methyl amino amino ester of phenyl cyclopentane carboxylic acid (Parpanit).
    Schweizerische medizinische Wochenschrift, 1948, Sep-18, Volume: 78, Issue:37

    Topics: Cyclopentanes

1948
The use of parpanit in rheumatic joint diseases.
    Schweizerische medizinische Wochenschrift, 1948, Oct-02, Volume: 78, Issue:39

    Topics: Arthritis; Cyclopentanes; Rheumatology

1948
The point of impact of the parpanit.
    Helvetica physiologica et pharmacologica acta, 1948, Volume: 6, Issue:3

    Topics: Cyclopentanes

1948
The influence of parpanit on the cellular respiration of the striated muscles.
    Helvetica physiologica et pharmacologica acta, 1948, Volume: 6, Issue:3

    Topics: Cyclopentanes; Muscles

1948
Parkinsonism treated with parpanit.
    Lancet (London, England), 1948, Nov-06, Volume: 2, Issue:6532

    Topics: Cyclopentanes; Parkinsonian Disorders

1948
Study of the influence of the ethylaminoethyl ester of phenyl-cyclopentane-carboxylic acid (parpanit) on the elevation of the combustion of parkinson patients.
    Schweizerische medizinische Wochenschrift, 1948, Oct-16, Volume: 78, Issue:41

    Topics: Cyclopentanes; Parkinsonian Disorders

1948
Pharmacological actions of the ethylaminoethyl ester of phenyl-cyclopentane-carboxylic acid (parpanit).
    Archives internationales de pharmacodynamie et de therapie, 1948, Jan-15, Volume: 75, Issue:3-4

    Topics: Cyclopentanes

1948
Pharmacological actions of the ethylaminoethyl ester of phenyl-cyclopentane-carboxylic acid (parpanit).
    Archives internationales de pharmacodynamie et de therapie, 1948, Jan-15, Volume: 75, Issue:3-4

    Topics: Cyclopentanes

1948
Clinical results with parpanit.
    Praxis, 1948, Mar-04, Volume: 37, Issue:9

    Topics: Cyclopentanes

1948
Pharmacological research on the ethylaminoethyl ester of phenylcyclopentanecarbonic acid (parpanit).
    Schweizerische medizinische Wochenschrift, 1948, Mar-13, Volume: 78, Issue:10

    Topics: Cyclopentanes

1948
Mode of action of Parpanit on the nervous functions of the normal organism.
    Helvetica physiologica et pharmacologica acta, 1948, Volume: 6, Issue:3

    Topics: Cyclopentanes

1948
Isobolographic analysis of caramiphen and lidocaine on spinal anesthesia in rats.
    Neuroscience letters, 2010, Jan-18, Volume: 469, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Combined; Anesthetics, Local; Animals; Cyclopentanes; Dose-Response Relationship, Drug; Drug Synergism; Injections, Spinal; Lidocaine; Male; Rats; Rats, Sprague-Dawley

2010
Parpanit Geigy.
    Schweizerische Apotheker Zeitung, 1947, Mar-22, Volume: 85, Issue:12

    Topics: Cyclopentanes

1947
The parpanit in neurological practice.
    Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale, 1947, Volume: 3, Issue:11

    Topics: Cyclopentanes

1947
A new therapy for extra-pyramidal motor disorders: "Parpanit".
    Medecine et hygiene, 1947, Jan-01, Volume: 5, Issue:89

    Topics: Brain; Cyclopentanes; Extrapyramidal Tracts; Humans; Movement Disorders; Nervous System

1947
About Parpanit, a new substance that influences extrapyramidal movement disorders.
    Praxis, 1947, Jan-16, Volume: 36, Issue:3

    Topics: Basal Ganglia Diseases; Cyclopentanes; Extrapyramidal Tracts; Humans

1947
Clinical experience in treating extrapyramidal disorders with a new agent, parpanit.
    Praxis, 1947, Jan-16, Volume: 36, Issue:3

    Topics: Basal Ganglia Diseases; Cyclopentanes; Extrapyramidal Tracts; Humans

1947
Antidepressant-like effect of centrally acting non-narcotic antitussive caramiphen in a forced swimming test.
    Neuroscience letters, 2010, Sep-13, Volume: 481, Issue:3

    Topics: Animals; Antidepressive Agents; Antitussive Agents; Behavior, Animal; Cyclopentanes; Male; Motor Activity; Rats; Rats, Wistar; Stress, Psychological; Swimming

2010
Neuroprotective efficacy of caramiphen against soman and mechanisms of its action.
    British journal of pharmacology, 2011, Volume: 164, Issue:5

    Topics: Animals; Behavior, Animal; Brain; Cell Count; Chemical Warfare Agents; Cyclopentanes; Dose-Response Relationship, Drug; Male; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Seizures; Soman; Synaptic Potentials

2011
Enhanced efficacy of anticonvulsants when combined with levetiracetam in soman-exposed rats.
    Neurotoxicology, 2011, Volume: 32, Issue:6

    Topics: Animals; Anticonvulsants; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Lethal Dose 50; Levetiracetam; Male; Motor Activity; Muscimol; Nicotinic Antagonists; Piracetam; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors

2011
The anticholinergic and antiglutamatergic drug caramiphen reduces seizure duration in soman-exposed rats: synergism with the benzodiazepine diazepam.
    Toxicology and applied pharmacology, 2012, Mar-15, Volume: 259, Issue:3

    Topics: Acetylcholinesterase; Animals; Anticonvulsants; Body Temperature; Body Weight; Cholinergic Antagonists; Cholinesterase Inhibitors; Cyclopentanes; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Male; Rats; Rats, Sprague-Dawley; Seizures; Soman; Time Factors

2012
Magnesium sulfate treatment against sarin poisoning: dissociation between overt convulsions and recorded cortical seizure activity.
    Archives of toxicology, 2013, Volume: 87, Issue:2

    Topics: Animals; Anticonvulsants; Antidotes; Brain Injuries; Cerebral Cortex; Chemical Warfare Agents; Cyclopentanes; Epilepsy, Tonic-Clonic; Magnesium Sulfate; Male; Midazolam; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Telemetry

2013
The perirhinal cortex of rats: an intricate area for microinfusion of anticonvulsants against soman-induced seizures.
    Neurotoxicology, 2013, Volume: 34

    Topics: Animals; Anticonvulsants; Brain Waves; Catheters, Indwelling; Cerebral Cortex; Cyclopentanes; Cyclopropanes; Disease Models, Animal; Drug Delivery Systems; Electroencephalography; Glycine; Infusions, Parenteral; Male; Micromanipulation; Procyclidine; Pyridines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors

2013
FOLICation: engineering approved drugs as potential p53-MDM2 interaction inhibitors for cancer therapy.
    Medical hypotheses, 2013, Volume: 81, Issue:6

    Topics: Clofazimine; Cyclopentanes; Drug Discovery; Folic Acid; Humans; Imidazoles; Indoles; Models, Molecular; Neoplasms; Piperazines; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-mdm2; Spiro Compounds; Tumor Suppressor Protein p53

2013
Caramiphen-induced block of sodium currents and spinal anesthesia.
    European journal of pharmacology, 2015, Jan-05, Volume: 746

    Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Behavior, Animal; Cell Line; Cyclopentanes; Dose-Response Relationship, Drug; Humans; Injections, Spinal; Male; Membrane Potentials; Mice; Motor Activity; Nerve Tissue Proteins; Neurons; Nociception; Patch-Clamp Techniques; Rats, Sprague-Dawley; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels

2015
Comparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric Population.
    The Journal of pharmacology and experimental therapeutics, 2018, Volume: 365, Issue:2

    Topics: Animals; Anticonvulsants; Anxiety; Basolateral Nuclear Complex; Behavior, Animal; Child; Cyclopentanes; Diazepam; Disease Models, Animal; Drug Interactions; Humans; Isoquinolines; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus; Tetrazoles

2018
Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.
    Neurotoxicity research, 2018, Volume: 34, Issue:3

    Topics: Animals; Anticonvulsants; Body Weight; Brain Injuries; Brain Waves; Cholinesterase Inhibitors; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Fluoresceins; Fourier Analysis; Isoquinolines; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures; Soman; Tetrazoles; Time Factors

2018
Electroencephalographic analysis in soman-exposed 21-day-old rats and the effects of midazolam or LY293558 with caramiphen.
    Annals of the New York Academy of Sciences, 2020, Volume: 1479, Issue:1

    Topics: Animals; Antidotes; Cyclopentanes; Electrocardiography; Isoquinolines; Male; Midazolam; Nerve Agents; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus; Tetrazoles

2020