Page last updated: 2024-08-23

captopril and zofenoprilate

captopril has been researched along with zofenoprilate in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's3 (17.65)18.2507
2000's7 (41.18)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cushman, DW; DeForrest, JM; Duggan, M; Karanewsky, DS; Krapcho, J; Powell, JR; Rovnyak, G; Schwartz, J; Spitzmiller, ER; Turk, C1
Topliss, JG; Yoshida, F1
de Graeff, PA; de Langen, CD; Tio, RA; van Gilst, WH; van Wijngaarden, J; Wesseling, H1
Dietze, GJ; Rett, K; Tio, RA; van Gilst, WH; Wesseling, H; Wolters, K1
Banditelli, S; Cappiello, M; Cecconi, I; Dal Monte, M; Del Corso, A; Moschini, R; Mura, U; Tsai, L; Vilardo, PG1
Dal Bo, L; Marzo, A; Mazzucchelli, P1
Bianchi, G; Fazio, F; Kienle, MG; Magni, F; Matarrese, M; Moresco, RM; Poma, D; Rossetti, C; Salimbeni, A; Sciarrone, MT; Todde, S; Turolla, EA; Turozzi, D1
Buikema, H; Schoemaker, RG; van Gilst, WH; van Veldhuisen, DJ; Westendorp, B1
Boggi, U; Bugliani, M; Del Guerra, S; Del Prato, S; Lupi, R; Marchetti, P; Mosca, F; Torri, S1
Donnini, S; Giachetti, A; Granger, HJ; Morbidelli, L; Solito, R; Ziche, M1
Catena, C; Donnini, D; Milocco, C; Moretti, M; Sechi, LA; Soardo, G1
Donnini, S; Morbidelli, L; Terzuoli, E; Ziche, M1
Bongianni, F; Cinelli, E; Evangelista, S; Mutolo, D; Pantaleo, T1
Di, B; Feng, F; Huang, L; Jiang, Y; Lu, J; Yan, F; You, L1
Ciccarelli, C; Desideri, G; Evangelista, S; Ferri, C; Festuccia, C; Grassi, D; Gravina, GL; Lovat, F; Marampon, F; Polidoro, L; Scarsella, L; Zani, BM1
Monti, M; Morbidelli, L; Terzuoli, E; Ziche, M1
Bucci, M; Cirino, G; Monti, M; Morbidelli, L; Terzuoli, E; Vellecco, V; Ziche, M1

Trials

1 trial(s) available for captopril and zofenoprilate

ArticleYear
11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat.
    Bioorganic & medicinal chemistry, 2004, Feb-01, Volume: 12, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Carbon Radioisotopes; Humans; Male; Middle Aged; Molecular Structure; Tissue Distribution; Tomography, Emission-Computed

2004

Other Studies

16 other study(ies) available for captopril and zofenoprilate

ArticleYear
Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Enalapril; Enalaprilat; Kinetics; Male; Phosphinic Acids; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1988
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Coronary vasodilation induced by captopril and zofenoprilat: evidence for a prostaglandin-independent mechanism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Epoprostenol; In Vitro Techniques; Male; Prodrugs; Rats; Rats, Inbred Strains; Vasodilation

1991
The effects of bradykinin and the ischemic isolated rat heart.
    Hormone and metabolic research. Supplement series, 1990, Volume: 22

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Circulation; Coronary Disease; Coronary Vessels; Enalaprilat; Indomethacin; Myocardium; Rats; Vasodilation

1990
Site-specific inactivation of aldose reductase by 4-hydroxynonenal.
    Archives of biochemistry and biophysics, 1998, Feb-15, Volume: 350, Issue:2

    Topics: Aldehyde Reductase; Aldehydes; Animals; Antioxidants; Captopril; Cattle; Cysteine; Dithiothreitol; Glutathione Disulfide; Lens, Crystalline; NADP

1998
Assay of zofenopril and its active metabolite zofenoprilat by liquid chromatography coupled with tandem mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, Dec-01, Volume: 749, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calibration; Captopril; Chromatography, Liquid; Drug Stability; Humans; Mass Spectrometry; Quality Control; Reference Standards; Reproducibility of Results

2000
Hydrochlorothiazide increases plasma or tissue angiotensin-converting enzyme-inhibitor drug levels in rats with myocardial infarction: differential effects on lisinopril and zofenopril.
    European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Creatinine; Drug Therapy, Combination; Heart Ventricles; Hydrochlorothiazide; Hypertrophy, Left Ventricular; Kidney; Kidney Function Tests; Lisinopril; Male; Myocardial Infarction; Peptidyl-Dipeptidase A; Prodrugs; Rats; Rats, Sprague-Dawley; Ventricular Function

2005
The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.
    European journal of endocrinology, 2006, Volume: 154, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Enalaprilat; Female; Glucose; Humans; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Middle Aged; Oxidative Stress; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tyrosine

2006
Fibroblast growth factor-2 mediates Angiotensin-converting enzyme inhibitor-induced angiogenesis in coronary endothelium.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Coronary Vessels; Endothelial Cells; Fibroblast Growth Factor 2; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Receptor, Bradykinin B1; Receptor, Fibroblast Growth Factor, Type 1; Swine

2006
Effects of antihypertensive drugs on alcohol-induced functional responses of cultured human endothelial cells.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:2

    Topics: Antihypertensive Agents; Captopril; Carbazoles; Carvedilol; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Endothelial Cells; Ethanol; Humans; Malondialdehyde; Nitric Oxide; Oxidative Stress; Propanolamines

2008
Sulfhydryl angiotensin-converting enzyme inhibitor promotes endothelial cell survival through nitric-oxide synthase, fibroblast growth factor-2, and telomerase cross-talk.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Apoptosis; Captopril; Caspase 3; Catalytic Domain; Cattle; Cell Survival; Cells, Cultured; Cellular Senescence; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Fibroblast Growth Factor 2; Humans; Microvessels; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Signal Transduction; Telomerase

2010
Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4

    Topics: Anesthesia, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Citric Acid; Consciousness; Cough; Drug Evaluation, Preclinical; Injections, Intravenous; Male; Rabbits; Ramipril; Reflex

2010
Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of zofenopril and its active metabolite zofenoprilat in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2011, Jun-01, Volume: 55, Issue:3

    Topics: Calibration; Captopril; Chromatography, High Pressure Liquid; Drug Stability; Humans; Indicators and Reagents; Limit of Detection; Molecular Structure; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry

2011
Angiotensin-converting-enzyme inhibition counteracts angiotensin II-mediated endothelial cell dysfunction by modulating the p38/SirT1 axis.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Apoptosis; Captopril; Cell Nucleus; Cell Survival; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; MAP Kinase Kinase 6; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Sirtuin 1; Superoxides

2013
The sulphydryl containing ACE inhibitor Zofenoprilat protects coronary endothelium from Doxorubicin-induced apoptosis.
    Pharmacological research, 2013, Volume: 76

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antibiotics, Antineoplastic; Apoptosis; Captopril; Cattle; Cell Line; Cell Line, Tumor; Coronary Vessels; Doxorubicin; Endothelium; Endothelium, Vascular; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; Tumor Suppressor Protein p53

2013
Characterization of zofenoprilat as an inducer of functional angiogenesis through increased H2 S availability.
    British journal of pharmacology, 2015, Volume: 172, Issue:12

    Topics: Angiogenesis Inducing Agents; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cystathionine gamma-Lyase; Endothelium, Vascular; Fibroblast Growth Factor 2; Human Umbilical Vein Endothelial Cells; Hydrogen Sulfide; KATP Channels; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Up-Regulation

2015