Page last updated: 2024-08-23

captopril and zofenopril

captopril has been researched along with zofenopril in 143 studies

Research

Studies (143)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (5.59)	18.7374
1990's	39 (27.27)	18.2507
2000's	40 (27.97)	29.6817
2010's	48 (33.57)	24.3611
2020's	8 (5.59)	2.80

Authors

Authors	Studies
Abbenante, G; Fairlie, DP; Leung, D	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Codd, R; Gotsbacher, MP; Roth, L	1
Boraso, A; Cargnoni, A; Ceconi, C; Curello, S; Ferrari, R; Visioli, O	1
Cordis, GA; Das, DK; Engelman, RM; Liu, X; Rousou, JA	1
Cushman, DW; Dzwonczyk, S; Fung, W; Grover, GJ; Sleph, PG; Tobias, D; Wang, P	1
Cassidy, MM; Freedman, AM; Weglicki, WB	1
Mendelsohn, FA; Sun, Y	1
Ambrosioni, E; Borghi, C; Magnani, B	4
de Graeff, PA; de Langen, CD; Pinto, YM; van Gilst, WH; van Wijngaarden, J; Wesseling, H	1
de Graeff, PA; Pinto, YM; van Gilst, WH; van Wijngaarden, J; Wesseling, H	1
Kloner, RA; Przyklenk, K	1
Lawson, DL; Mehta, JL; Saldeen, K	1
Arnold, ME; Burkett, DE; D'Arienzo, CJ; Morrison, RA; Weinstein, SH	1
Bel, KJ; de Graeff, PA; de Langen, CD; Mook, PH; Tio, RA; van Gilst, WH; van Wijngaarden, J; Wesseling, H; Wolters, KG	1
Chopra, M; Dargie, HJ; McMurray, J; Smith, WE; Stewart, J	1
Carlyle, PF; Cohn, JN; Elbers, T; Hauer, K; Hunter, D; Matthews, J; McDonald, KM	1
Foley, JE; Morrison, RA; Singhvi, SM; Willard, DA	1
Cushman, DW; DeForrest, JM; Krapcho, J; Petrillo, EW; Powell, JR; Rubin, B; Turk, C; Waldron, TL	1
Ambrosioni, E; Borghi, C; Boschi, S; Capelli, M; Costa, FV; Magelli, C; Magnani, B; Varani, E	1
de Langen, CD; Scholtens, E; Tio, RA; van Gilst, WH; van Wijngaarden, J; Wesseling, H	1
Cushman, DW; DeForrest, JM; Fung, WC; Grover, GJ; Harvey, CM; Mitch, SL; Scalese, RJ; Wang, FL	1
Mackaness, GB	1
Lacourcière, Y; Provencher, P	1
Gagné, C; Lacourcière, Y	1
Cohen, AI; Ivashkiv, E; Jemal, M; Teitz, D	1
Gurbel, PA; O'Connor, CM	1
Mikus, G; Mörike, K	1
Chaudhry, GM; Haneef, N	1
de Teresa, E	1
Ambrosioni, E; Bacchelli, S; Borghi, C	1
Pfeffer, MA	1
Joseph, JM; Kline, BJ; Lozano, R	1
Ambrosioni, E; Borghi, C; Boschi, S; Branzi, A; Magnani, B; Melandri, G	1
Binkley, PF; Cody, RJ; Haas, GJ; Hatton, PA; Leier, CV; Nunziata, E; Starling, RC	1
Antonaccio, MJ; Dzwonczyk, S; Grover, GJ; Normandin, D; Sargent, CA; Sleph, PG; Smith, MA	1
Agner, E; Kelbaek, H; Marving, J; Vasehus Madsen, P; Wroblewski, H	1
Finn, PV; Mitchell, GF; Pfeffer, JM; Pfeffer, MA	1
Gasser, R; Holzmann, S; Klein, W; Köppel, H	1
Bathala, MS; Dean, AV; Jain, NB; Kripalani, KJ; Marino, AM; Migdalof, BH; Morrison, RA; Singhvi, SM; Weinstein, SH	1
Gasser, R; Holzmann, S; Horn, E; Horn, S; Klein, W; Köppel, H	1
Elijovich, F; Laffer, CL; Schiffrin, EL	1
Anning, PB; Grocott-Mason, RM; Lewis, MJ	1
Akarawut, W; Lin, CJ; Smith, DE	1
Ambrosioni, E; Bacchelli, S; Bignamini, A; Borghi, C; Esposti, DD; Magnani, B	1
Crivelli, F; Dal Bo, L; Giusti, A; Ismaili, S; Marzo, A; Mazzucchelli, P; Monti, NC; Tettamanti, RA; Uhr, MR	1
Aleotti, L; Bucci, M; Casini, A; Cicala, C; Cirino, G; D'Armiento, FP; de Nigris, F; Franconi, F; Napoli, C; Roviezzo, F; Somma, P; Zuliani, P	1
Brilla, CG	1
Buikema, H; Crijns, HJ; de Zeeuw, D; Monnink, SH; Tio, RA; van Gilst, WH	1
Dal Bo, L; Marzo, A; Mazzucchelli, P	1
Bigioni, M; Evangelista, S; Goso, C; Maggi, CA; Manzini, S; Sacco, G	1
Andreini, I; Bonaduce, D; Casini, A; Condorelli, M; D'Armiento, FP; de Nigris, F; De Rosa, G; Mansueto, G; Napoli, C; Sarlo, F; Somma, P	1
Crivelli, F; Dal Bo, L; Giusti, A; Ismaili, S; Marzo, A; Mazzucchelli, P; Monti, NC; Uhr, MR	1
Cominacini, L; Crea, AE; Davoli, A; Evangelista, S; Garbin, U; LoCascio, V; Nava, C; Pasini, A; Tagliacozzi, D	1
Altamura, M; Animati, F; Balacco, G; Cartoni, A; Cosi, R; Ettorre, A; Madami, A; Triolo, A	1
Ambrosioni, E; Borghi, C	2
Ambrosioni, E; Bacchelli, S; Borghi, C; Esposti, DD	1
Frascarelli, S; Ghelardoni, S; Ronca-Testoni, S; Zucchi, R	1
Bianchi, G; Fazio, F; Kienle, MG; Magni, F; Matarrese, M; Moresco, RM; Poma, D; Rossetti, C; Salimbeni, A; Sciarrone, MT; Todde, S; Turolla, EA; Turozzi, D	1
Buikema, H; de Zeeuw, D; Schoemaker, RG; van Gilst, WH; van Veldhuisen, DJ; Westendorp, B	1
Condorelli, M; de Nigris, F; Ignarro, LJ; Liguori, A; Napoli, C; Pignalosa, O; Sica, V	1
Ambrosioni, E; Bacchelli, S; Borghi, C; Degli Esposti, D	2
Alcaraz, A; Atucha, NM; Evangelista, S; García-Estañ, J; Navarro, EG; O'Valle, F; Ortiz, MC; Vargas, F	1
Buikema, H; Schoemaker, RG; van Gilst, WH; van Veldhuisen, DJ; Westendorp, B	1
Malacco, E; Parati, G; Zanchetti, A	1
Batyraliev, TA; Pataraia, SA; Pershukov, IV; Preobrazhenskiĭ, DV; Sidorenko, BA	1
Altunoluk, B; Fadillioglu, E; Oguz, F; Soylemez, H; Turkmen, E	1
Ivleva, AIa	1
Buikema, H	1
Borghi, C; Cicero, AF	1
Ambrosioni, E	1
Boccioletti, V; Cominacini, L; Fabrizzi, P; Garbin, U; Lo Cascio, V; Luchetta, ML; Nava, MC; Pasini, AF; Pellegrini, M; Stranieri, C	1
Teyssedou, A	1
Hedner, T; Kjeldsen, SE; Narkiewicz, K	1
Narkiewicz, K	1
Mallion, JM	1
Farsang, C	1
Nilsson, P	1
Ambrosioni, E; Borghi, C; Cicero, AF	1
Bruzzese, G; Cacciatore, F; Crimi, E; de Nigris, F; Fiorito, C; Ignarro, LJ; Libardi, S; Liguori, A; Mancini, FP; Napoli, C; Sommese, L; Williams-Ignarro, S	1
Ambrosioni, E; Bacchelli, S; Borghi, C; Cicero, AF; Esposti, DD	1
Carnicelli, V; Chiellini, G; Frascarelli, S; Ghelardoni, S; Ronca, F; Zucchi, R	1
Malacco, E; Omboni, S; Parati, G	1
Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA	2
Carlucci, G; Di Federico, L; Iuliani, P	1
Celi, A; Cianchetti, S; Del Fiorentino, A; Pedrinelli, R	1
Cialdai, C; Giuliani, S; Maggi, CA; Tramontana, M; Valenti, C	1
Bongianni, F; Cinelli, E; Evangelista, S; Mutolo, D; Pantaleo, T	1
Di, B; Feng, F; Huang, L; Jiang, Y; Lu, J; Yan, F; You, L	1
Carnicelli, V; Frascarelli, S; Zucchi, R	1
Bruzzese, G; Cacciatore, F; de Nigris, F; Donatelli, F; Fiorito, C; Ignarro, LJ; Infante, T; Liguori, A; Minucci, PB; Napoli, C; Vitale, DF	1
Abuladze, GV; Erkomaishvili, IG; Narsiia, EV; Nebieridze, MI; Pipiia, NG	1
Acar, A; Alp, H; Evliyaoğlu, O; Fırat, U; Göçmez, C; Ilhan, A; Kamasak, K; Taşdemir, N; Tüfek, A; Uzar, E	1
Angelescu, G; Bălan, H; Popescu, E	1
Altunoluk, B; Bakan, V; Ciralik, H; Söylemez, H; Tolun, FI	1
Citraro, R; Gallelli, L; Gareri, P; Gratteri, S; Paola, ED; Rispoli, V; Russo, E; Sarro, GD; Siniscalchi, A; Tripepi, G	1
Bozcali, E; Dedeoglu, DB; Karpuz, H; Karpuz, V; Suzer, O	1
Ambrosio, G; Ambrosioni, E; Borghi, C; Novo, S; Vinereanu, D	1
Bacchelli, S; Borghi, C; Degli Esposti, D	1
Gumustas, M; Kurbanoglu, S; Ozkan, SA	1
Carubelli, V; Castrini, AI; Dei Cas, L; Inama, L; Lazzarini, V; Lombardi, C; Metra, M	1
Ambrosio, G; Ambrosioni, E; Bacchelli, S; Borghi, C; Cicero, AF; Esposti, DD; Omboni, S; Vinereanu, D; Zava, D	1
Borghi, C; Cicero, AF; Cosentino, ER; Rinaldi, ER	1
Borghi, C; Del Corso, F; Pareo, I	1
Nageswara Rao, P; Nageswara Rao, R; Ramesh, T	1
Agabiti-Rosei, E; Manolis, A; Omboni, S; Zava, D	1
Brancaleone, V; Bucci, M; Calderone, V; Cantalupo, A; Cirino, G; Evangelista, S; Papapetropoulos, A; Vellecco, V; Zhou, Z	1
Cao, J; Luo, L; Ma, P; Tian, Y; Zhang, Z	1
Borghi, C; Omboni, S	3
Ambrosioni, E; Borghi, C; Campesi, I; Franconi, F; Omboni, S; Reggiardo, G	1
Albayrak, A; Delibasi, T; Dogan, AC; Dogan, M; Eren, F; Fadillioglu, E; Karateke, A; Keskin Kurt, R; Kurt, SN; Silfeler, DB	1
Dralova, OV; Ermolaeva, AS; Maksimov, ML	1
Apola, A; Krzek, J; Maślanka, A; Rybak, W; Stolarczyk, M	1
Arca, M; Berra, S; Bucci, M; Calabrò, P; Fulgheri, PL; Ghione, S; Modesti, PA; Omboni, S; Pirvu, O; Popescu, E; Portaluppi, F; Pozzilli, P; Taddei, S; Velican, VG; Villani, GQ; Vladoianu, M; Volpe, M	1
Ambrosio, G; Ambrosioni, E; Borghi, C; Novo, S; Omboni, S; Vinereanu, D	4
Ali, MJ; Bradley, JM; Cirino, G; Donnarumma, E; Evangelista, S; Goodchild, TT; Islam, KN; Jenkins, JS; Lefer, DJ; Organ, CL; Patel, RA; Polhemus, DJ; Rushing, AM; Scarborough, AL	1
Borghi, C; Napoli, C; Omboni, S	1
Ambrosioni, E; Bacchelli, S; Borghi, C; Degli Esposti, D; Omboni, S; Reggiardo, G	3
Jakovljevic, VL; Nikolic, T; Ristic, D; Ristic, P; Srejovic, I; Stojic, I; Zivkovic, V	1
Agabiti-Rosei, E; Borghi, C; Malacco, E; Manolis, A; Modesti, PA; Napoli, C; Omboni, S; Parati, G	1
de Nucci, G; Dicay, M; MacNaughton, WK; Vaughan, D; Wallace, JL	1
Abbas, SS; Fayed, AS; Marzouk, HM; Rezk, MR	2
Ambrosioni, E; Bacchelli, S; Borghi, C; Esposti, DD; Omboni, S; Reggiardo, G	1
Kravchun, PG; Martovytskyi, DV; Shelest, OM	1
Ambrosio, G; Borghi, C; Mancia, G; Van De Borne, P	1
Desai, M	1
Allagnat, F; Corpataux, JM; Déglise, S; Deslarzes-Dubuis, C; Lambelet, M; Longchamp, A; Macabrey, D; Ozaki, CK	1
Heiman, F; Meto, S; Peduto, I; Pegoraro, V; Volpe, M	1
Aydemir, BG; Baka, T; Barta, A; Berenyiova, A; Bernatova, I; Cacanyiova, S; Cebova, M; Kluknavsky, M; Krskova, K; Shaman, E; Simko, F; Zemancikova, A; Zorad, S	1

Reviews

23 review(s) available for captopril and zofenopril

Article	Year
Protease inhibitors: current status and future prospects. Journal of medicinal chemistry, 2000, Feb-10, Volume: 43, Issue:3 Topics: Animals; Aspartic Acid Endopeptidases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Metalloendopeptidases; Models, Molecular; Protease Inhibitors; Serine Endopeptidases; Serine Proteinase Inhibitors	2000
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
The use of zofenopril and fosinopril in acute myocardial infarction and carotid artery disease. American journal of hypertension, 1994, Volume: 7, Issue:9 Pt 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Arteriosclerosis; Captopril; Carotid Artery Diseases; Clinical Trials as Topic; Fosinopril; Humans; Myocardial Infarction	1994
A review of the angiotensin-converting enzyme inhibitor, zofenopril, in the treatment of cardiovascular diseases. Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:9 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiovascular Diseases; Clinical Trials as Topic; Heart; Humans; Hypertension; Myocardial Infarction	2004
Zofenopril plus hydrochlorothiazide: Combination therapy for the treatment of mild to moderate hypertension. Drugs, 2006, Volume: 66, Issue:8 Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged	2006
[Angiotensin converting enzyme inhibitors in acute period of myocardial infarction: the place of zofenopril]. Kardiologiia, 2006, Volume: 46, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Disease Progression; Follow-Up Studies; Heart Failure; Humans; Myocardial Contraction; Myocardial Infarction; Time Factors; Treatment Outcome	2006
[Efficacy of a new ACE inhibitor zofenopril (zocardis) in cardiovascular diseases]. Terapevticheskii arkhiv, 2006, Volume: 78, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiovascular Diseases; Humans; Treatment Outcome	2006
Use of the ACE inhibitor zofenopril in the treatment of ischemic heart disease. Expert review of cardiovascular therapy, 2006, Volume: 4, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Captopril; Cardiac Output, Low; Cardiotonic Agents; Chronic Disease; History, 19th Century; History, 20th Century; Humans; Myocardial Infarction; Myocardial Ischemia	2006
Fixed combination of zofenopril plus hydrochlorothiazide in the management of hypertension: a review of available data. Vascular health and risk management, 2006, Volume: 2, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Diseases; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Severity of Illness Index; Treatment Outcome	2006
Defining the role of zofenopril in the management of hypertension and ischemic heart disorders. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2007, Volume: 7, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Administration Schedule; Humans; Hypertension; Myocardial Ischemia; Treatment Outcome	2007
Zofenopril plus hydrochlorothiazide fixed combination in the treatment of hypertension and associated clinical conditions. Cardiovascular therapeutics, 2009,Winter, Volume: 27, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Metabolic Diseases	2009
[Efficiancy Angiotensin -converting enzyme inhibitors for the clinical practice]. Georgian medical news, 2011, Issue:195 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Diabetic Cardiomyopathies; Heart Failure; Humans; Hypertension; Myocardial Infarction	2011
Long-term clinical experience with zofenopril. Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspirin; Captopril; Coronary Artery Disease; Drug Interactions; Evidence-Based Medicine; Heart Failure; Humans; Hypertension; Myocardial Infarction; Platelet Aggregation Inhibitors	2012
Evolving concept of cardioprotection in myocardial infarction: from SMILE-1 to SMILE-5. Kardiologia polska, 2013, Volume: 71, Issue:7 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiotonic Agents; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Renin-Angiotensin System	2013
Zofenopril plus hydrochlorothiazide combination in the treatment of hypertension: an update. Expert review of cardiovascular therapy, 2014, Volume: 12, Issue:9 Topics: Animals; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Captopril; Cardiovascular Diseases; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Practice Guidelines as Topic; Risk Factors	2014
[Modem inhibitor angiotensin-converting enzyme zofenopril in the primary and secondary prevention of cardiovascular disease]. Kardiologiia, 2014, Volume: 54, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Humans; Hypertension; Myocardial Ischemia; Outcome Assessment, Health Care; Renin-Angiotensin System	2014
Efficacy of Zofenopril Compared With Placebo and Other Angiotensin-converting Enzyme Inhibitors in Patients With Acute Myocardial Infarction and Previous Cardiovascular Risk Factors: A Pooled Individual Data Analysis of 4 Randomized, Double-blind, Control Journal of cardiovascular pharmacology, 2017, Volume: 69, Issue:1 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiovascular Diseases; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Treatment Outcome	2017
Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized "Z" Studies. Advances in therapy, 2017, Volume: 34, Issue:4 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; C-Reactive Protein; Captopril; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Inflammation Mediators; Irbesartan; Lipids; Male; Middle Aged; Pulse Wave Analysis; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Vascular Stiffness	2017
Hydrogen Sulfide-Releasing Therapeutics: Translation to the Clinic. Antioxidants & redox signaling, 2018, 06-01, Volume: 28, Issue:16 Topics: Animals; Arthritis; Captopril; Cardiovascular Agents; Cardiovascular Diseases; Dose-Response Relationship, Drug; Humans; Hydrogen Sulfide; Naproxen	2018
Efficacy and Safety of Zofenopril Versus Ramipril in the Treatment of Myocardial Infarction and Heart Failure: A Review of the Published and Unpublished Data of the Randomized Double-Blind SMILE-4 Study. Advances in therapy, 2018, Volume: 35, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Heart Failure; Humans; Myocardial Infarction; Ramipril; Randomized Controlled Trials as Topic; Treatment Outcome	2018
Effects of the concomitant administration of xanthine oxidase inhibitors with zofenopril or other ACE-inhibitors in post-myocardial infarction patients: a meta-analysis of individual data of four randomized, double-blind, prospective studies. BMC cardiovascular disorders, 2018, 06-05, Volume: 18, Issue:1 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Lisinopril; Male; Middle Aged; Myocardial Infarction; Progression-Free Survival; Prospective Studies; Ramipril; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Xanthine Oxidase	2018
Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction. Current clinical pharmacology, 2019, Volume: 14, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Kidney Diseases; Treatment Outcome	2019
Angiotensin-Converting Enzyme Inhibition: Beyond Blood Pressure Control-The Role of Zofenopril. Advances in therapy, 2020, Volume: 37, Issue:10 Topics: Angiotensins; Blood Pressure; Captopril; Humans; Treatment Outcome	2020

Trials

38 trial(s) available for captopril and zofenopril

Article	Year
Early treatment of acute myocardial infarction with angiotensin-converting enzyme inhibition: safety considerations. SMILE pilot study working party. The American journal of cardiology, 1991, Nov-18, Volume: 68, Issue:14 Topics: Administration, Oral; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cardiac Output; Echocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Placebos; Pulmonary Wedge Pressure; Renin; Renin-Angiotensin System; Safety; Stroke Volume; Treatment Outcome; Vascular Resistance; Ventricular Function, Left	1991
Comparative effects of zofenopril and hydrochlorothiazide on office and ambulatory blood pressures in mild to moderate essential hypertension. British journal of clinical pharmacology, 1989, Volume: 27, Issue:3 Topics: Adult; Aged; Blood Pressure; Captopril; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monitoring, Physiologic	1989
Influence of zofenopril and low doses of hydrochlorothiazide on plasma lipoproteins in patients with mild to moderate essential hypertension. American journal of hypertension, 1989, Volume: 2, Issue:11 Pt 1 Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Apolipoproteins; Captopril; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Randomized Controlled Trials as Topic	1989
The effect of the angiotensin-converting-enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction. The Survival of Myocardial Infarction Long-Term Evaluation (SMILE) Study Investigators. The New England journal of medicine, 1995, Jan-12, Volume: 332, Issue:2 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Confidence Intervals; Double-Blind Method; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Morbidity; Myocardial Infarction; Treatment Outcome	1995
Survival of myocardial infarction long-term evaluation (SMILE) study: rationale, design, organization, and outcome definitions. Controlled clinical trials, 1994, Volume: 15, Issue:3 Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Female; Heart Failure; Humans; Long-Term Care; Male; Middle Aged; Myocardial Infarction; Survival Rate; Treatment Outcome	1994
Evidence of a partial escape of renin-angiotensin-aldosterone blockade in patients with acute myocardial infarction treated with ACE inhibitors. Journal of clinical pharmacology, 1993, Volume: 33, Issue:1 Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Humans; Myocardial Infarction; Renin; Renin-Angiotensin System	1993
Sustained augmentation of parasympathetic tone with angiotensin-converting enzyme inhibition in patients with congestive heart failure. Journal of the American College of Cardiology, 1993, Mar-01, Volume: 21, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Electrocardiography; Female; Fourier Analysis; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Parasympathetic Nervous System; Signal Processing, Computer-Assisted; Time Factors	1993
Angiotensin converting enzyme inhibition at rest and during exercise in congestive heart failure. European heart journal, 1993, Volume: 14, Issue:5 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Digoxin; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged	1993
Effects of the early administration of zofenopril on onset and progression of congestive heart failure in patients with anterior wall acute myocardial infarction. The SMILE Study Investigators. Survival of Myocardial Infarction Long-term Evaluation. The American journal of cardiology, 1996, Aug-01, Volume: 78, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Captopril; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Heart Failure; Humans; Italy; Male; Middle Aged; Myocardial Infarction; Prevalence; Prospective Studies; Time Factors	1996
The effects of atenolol and zofenopril on plasma atrial natriuretic peptide are due to their interactions with target organ damage of essential hypertensive patients. Journal of human hypertension, 1997, Volume: 11, Issue:5 Topics: Antihypertensive Agents; Atenolol; Atrial Natriuretic Factor; Blood Pressure; Captopril; Double-Blind Method; Drug Interactions; Hemodynamics; Humans; Hypertension	1997
Effects of the administration of an angiotensin-converting enzyme inhibitor during the acute phase of myocardial infarction in patients with arterial hypertension. SMILE Study Investigators. Survival of Myocardial Infarction Long-term Evaluation. American journal of hypertension, 1999, Volume: 12, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Incidence; Italy; Male; Middle Aged; Myocardial Infarction; Survival Rate; Treatment Outcome; Ventricular Function, Left	1999
Pharmacokinetics and pharmacodynamics of zofenopril in healthy volunteers. Arzneimittel-Forschung, 1999, Volume: 49, Issue:12 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Area Under Curve; Captopril; Female; Half-Life; Humans; Male; Peptidyl-Dipeptidase A	1999
Pharmacokinetic and pharmacodynamic comparative study of zofenopril and enalapril in healthy volunteers. Arzneimittel-Forschung, 2002, Volume: 52, Issue:4 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Area Under Curve; Biotransformation; Blood Pressure; Captopril; Chromatography, High Pressure Liquid; Enalapril; Female; Heart Rate; Humans; Male; Peptidyl-Dipeptidase A	2002
Double-blind comparison between zofenopril and lisinopril in patients with acute myocardial infarction: results of the Survival of Myocardial Infarction Long-term Evaluation-2 (SMILE-2) study. American heart journal, 2003, Volume: 145, Issue:1 Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Hypotension; Lisinopril; Male; Middle Aged; Myocardial Infarction; Recurrence; Survival Rate	2003
Effects of the early ACE inhibition in diabetic nonthrombolyzed patients with anterior acute myocardial infarction. Diabetes care, 2003, Volume: 26, Issue:6 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Creatine Kinase; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Risk Factors; Smoking; Survival Analysis; Time Factors	2003
11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat. Bioorganic & medicinal chemistry, 2004, Feb-01, Volume: 12, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Carbon Radioisotopes; Humans; Male; Middle Aged; Molecular Structure; Tissue Distribution; Tomography, Emission-Computed	2004
Sulfhydryl angiotensin-converting enzyme inhibition induces sustained reduction of systemic oxidative stress and improves the nitric oxide pathway in patients with essential hypertension. American heart journal, 2004, Volume: 148, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Arginine; Captopril; Enalapril; Female; Humans; Hypertension; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress	2004
Effects of early angiotensin-converting enzyme inhibition in patients with non-ST-elevation acute anterior myocardial infarction. American heart journal, 2006, Volume: 152, Issue:3 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Time Factors	2006
Effects of zofenopril on myocardial ischemia in post-myocardial infarction patients with preserved left ventricular function: the Survival of Myocardial Infarction Long-term Evaluation (SMILE)-ISCHEMIA study. American heart journal, 2007, Volume: 153, Issue:3 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Female; Heart; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Ventricular Function, Left	2007
Effect of sulfhydryl and non-sulfhydryl angiotensin-converting enzyme inhibitors on endothelial function in essential hypertensive patients. American journal of hypertension, 2007, Volume: 20, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Glucose; Blood Pressure; Captopril; Cell Adhesion Molecules; Cholesterol, HDL; Endothelium, Vascular; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Ramipril; Sulfhydryl Compounds; Triglycerides; Vasodilation	2007
Comparison of home and office blood pressure in hypertensive patients treated with zofenopril or losartan. Blood pressure. Supplement, 2007, Volume: 2 Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Office Visits	2007
An evaluation of the initial and long-term antihypertensive efficacy of zofenopril compared with enalapril in mild to moderate hypertension. Blood pressure. Supplement, 2007, Volume: 2 Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged	2007
Blood pressure control and response rates with zofenopril compared with amlodipine in hypertensive patients. Blood pressure. Supplement, 2007, Volume: 2 Topics: Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Treatment Outcome	2007
Antihypertensive efficacy of zofenopril compared with atenolol in patients with mild to moderate hypertension. Blood pressure. Supplement, 2007, Volume: 2 Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Time Factors; Treatment Outcome	2007
Effects of early treatment with zofenopril in patients with myocardial infarction and metabolic syndrome: the SMILE Study. Vascular health and risk management, 2008, Volume: 4, Issue:3 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Comorbidity; Female; Heart Failure; Humans; Incidence; Male; Metabolic Syndrome; Middle Aged; Myocardial Infarction	2008
Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension. American heart journal, 2008, Volume: 156, Issue:6 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Carotid Arteries; Carotid Stenosis; Dinoprost; Enalapril; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Tunica Intima; Tunica Media; Ultrasonography	2008
Serum cholesterol levels on admission and survival in patients with acute myocardial infarction treated with zofenopril: a post hoc analysis of the Survival of Myocardial Infarction Long-term Evaluation trial. Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:5 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cholesterol, LDL; Diagnostic Tests, Routine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Time Factors; Treatment Outcome	2009
Effects of ACE inhibition on circulating endothelial progenitor cells, vascular damage, and oxidative stress in hypertensive patients. European journal of clinical pharmacology, 2011, Volume: 67, Issue:9 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Carotid Arteries; Cell Count; Cell Movement; Cells, Cultured; Enalapril; Endothelial Cells; Follow-Up Studies; Humans; Hypertension; Isoprostanes; Middle Aged; Nitrates; Nitrites; Regression Analysis; Stem Cells; Treatment Outcome; Tunica Intima; Ultrasonography	2011
Comparing different treatment schedules of Zomen (zofenopril). Romanian journal of internal medicine = Revue roumaine de medecine interne, 2011, Volume: 49, Issue:1 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Dose-Response Relationship, Drug; Drug Chronotherapy; Female; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Treatment Outcome	2011
Comparison between zofenopril and ramipril in combination with acetylsalicylic acid in patients with left ventricular systolic dysfunction after acute myocardial infarction: results of a randomized, double-blind, parallel-group, multicenter, European stud Clinical cardiology, 2012, Volume: 35, Issue:7 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Heart Failure; Hospitalization; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Prospective Studies; Ramipril; Risk Assessment; Risk Factors; Stroke Volume; Systole; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left	2012
Zofenopril and ramipril and acetylsalicylic acid in postmyocardial infarction patients with left ventricular systolic dysfunction: a retrospective analysis in hypertensive patients of the SMILE-4 study. Journal of hypertension, 2013, Volume: 31, Issue:6 Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Captopril; Europe; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ramipril; Randomized Controlled Trials as Topic; Retrospective Studies; Ventricular Dysfunction, Left	2013
Effect of zofenopril and ramipril on cardiovascular mortality in patients with chronic heart failure. The American journal of cardiology, 2013, Jul-01, Volume: 112, Issue:1 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chronic Disease; Endpoint Determination; Female; Heart Failure; Humans; Male; Proportional Hazards Models; Prospective Studies; Ramipril; Survival Rate; Treatment Outcome	2013
Zofenopril plus hydrochlorothiazide and irbesartan plus hydrochlorothiazide in previously treated and uncontrolled diabetic and non-diabetic essential hypertensive patients. Advances in therapy, 2014, Volume: 31, Issue:2 Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Captopril; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Young Adult	2014
Zofenopril or irbesartan plus hydrochlorothiazide in elderly patients with isolated systolic hypertension untreated or uncontrolled by previous treatment: a double-blind, randomized study. Journal of hypertension, 2016, Volume: 34, Issue:3 Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Systole; Tetrazoles; Treatment Outcome; Vascular Stiffness	2016
Fixed-dose combination of zofenopril plus hydrochlorothiazide vs. irbesartan plus hydrochlorothiazide in hypertensive patients with established metabolic syndrome uncontrolled by previous monotherapy. The ZAMES study (Zofenopril in Advanced MEtabolic Synd Journal of hypertension, 2016, Volume: 34, Issue:11 Topics: Aged; Biphenyl Compounds; Captopril; Female; Humans; Hydrochlorothiazide; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Tetrazoles	2016
Zofenopril and ramipril in patients with left ventricular systolic dysfunction after acute myocardial infarction: A propensity analysis of the Survival of Myocardial Infarction Long-term Evaluation (SMILE) 4 study. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2016, Volume: 17, Issue:4 Topics: Captopril; Demography; Drug Therapy, Combination; Endpoint Determination; Female; Hospitalization; Humans; Intention to Treat Analysis; Male; Middle Aged; Myocardial Infarction; Propensity Score; Ramipril; Survival Analysis; Time Factors; Ventricular Dysfunction, Left	2016
Cardioprotective role of zofenopril in hypertensive patients with acute myocardial infarction: a pooled individual data analysis of the SMILE studies. Blood pressure, 2017, Volume: 26, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Retrospective Studies; Risk Factors	2017
Efficacy of zofenopril in combination with amlodipine in patients with acute myocardial infarction: a pooled individual patient data analysis of four randomized, double-blind, controlled, prospective studies. Current medical research and opinion, 2018, Volume: 34, Issue:10 Topics: Aged; Amlodipine; Antihypertensive Agents; Captopril; Data Analysis; Double-Blind Method; Female; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Time-to-Treatment; Treatment Outcome	2018

Other Studies

82 other study(ies) available for captopril and zofenopril

Article	Year
Immobilized Metal Affinity Chromatography as a Drug Discovery Platform for Metalloenzyme Inhibitors. Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20 Topics: Chromatography, Affinity; Coordination Complexes; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Humans; Imino Acids; Metalloproteins; Metals, Heavy; Models, Molecular; Molecular Structure; Structure-Activity Relationship	2020
Protection of the ischemic myocardium by the converting-enzyme inhibitor zofenopril: insight into its mechanism of action. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5 Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; Creatine Kinase; Hemodynamics; In Vitro Techniques; Lactates; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Norepinephrine; Oxidation-Reduction; Phosphocreatine; Rabbits	1992
Attenuation of myocardial reperfusion injury by sulfhydryl-containing angiotensin converting enzyme inhibitors. Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Coronary Circulation; Creatine Kinase; Fosinopril; Free Radical Scavengers; In Vitro Techniques; Lipid Peroxidation; Male; Membrane Lipids; Myocardial Reperfusion Injury; Myocardium; Phospholipids; Proline; Rats; Rats, Inbred Strains; Ventricular Function, Left	1992
Effects of different angiotensin-converting enzyme (ACE) inhibitors on ischemic isolated rat hearts: relationship between cardiac ACE inhibition and cardioprotection. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Coronary Disease; Drug Stability; Enalaprilat; Fosinopril; Heart; In Vitro Techniques; Male; Myocardium; Organophosphorus Compounds; Prodrugs; Proline; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Sulfhydryl Compounds	1991
Captopril protects against myocardial injury induced by magnesium deficiency. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:2 Topics: Analysis of Variance; Animals; Antihypertensive Agents; Captopril; Cardiomyopathies; Cricetinae; Diagnosis, Computer-Assisted; Enalaprilat; Magnesium Deficiency; Male; Myocardium	1991
Angiotensin converting enzyme inhibition in heart, kidney, and serum studied ex vivo after administration of zofenopril, captopril, and lisinopril. Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Autoradiography; Captopril; Enalapril; Iodine Radioisotopes; Kidney; Lisinopril; Male; Myocardium; Oxidation-Reduction; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains	1991
Converting enzyme inhibition after experimental myocardial infarction in rats: comparative study between spirapril and zofenopril. Cardiovascular research, 1991, Volume: 25, Issue:11 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Enalapril; Heart; Heart Rate; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats; Rats, Inbred Strains	1991
The effects of short- and long-term treatment with an ACE-inhibitor in rats with myocardial infarction. Basic research in cardiology, 1991, Volume: 86 Suppl 1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomegaly; Heart Ventricles; Male; Myocardial Infarction; Organ Size; Rats; Rats, Inbred Strains; Time Factors	1991
Angiotensin converting enzyme inhibitors improve contractile function of stunned myocardium by different mechanisms of action. American heart journal, 1991, Volume: 121, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Coronary Circulation; Dogs; Enalaprilat; Indomethacin; Myocardial Contraction; Myocardial Reperfusion Injury; Prostaglandins; Sulfhydryl Compounds	1991
Angiotensin converting enzyme inhibitors potentiate the vasorelaxant effect of fibrinogen-derived peptide 6A. Thrombosis research, 1991, Jan-01, Volume: 61, Issue:1 Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Drug Synergism; Enalaprilat; Fibrin Fibrinogen Degradation Products; In Vitro Techniques; Molecular Sequence Data; Rats; Vasodilation	1991
Sites of first-pass bioactivation (hydrolysis) of orally administered zofenopril calcium in dogs. Pharmaceutical research, 1991, Volume: 8, Issue:3 Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dogs; Gastric Mucosa; Hydrolysis; Infusions, Intra-Arterial; Infusions, Intravenous; Liver; Lung; Male; Prodrugs	1991
The effects of oral pretreatment with zofenopril, an angiotensin-converting enzyme inhibitor, on early reperfusion and subsequent electrophysiologic stability in the pig. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:3 Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Coronary Disease; Creatine Kinase; Electric Stimulation; Heart; Heart Rate; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Purines; Renin; Swine; Tachycardia; Time Factors; Ventricular Function	1990
Free radical scavenging: a potentially beneficial action of thiol-containing angiotensin converting enzyme inhibitors. Biochemical Society transactions, 1990, Volume: 18, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Evaluation, Preclinical; Free Radical Scavengers; Humans; In Vitro Techniques; Myocardial Reperfusion Injury	1990
Early ventricular remodeling after myocardial damage and its attenuation by converting enzyme inhibition. Transactions of the Association of American Physicians, 1990, Volume: 103 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomegaly; Disease Models, Animal; Dogs; Heart Injuries; Heart Ventricles	1990
Disposition of zofenopril calcium in healthy subjects. Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:11 Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Biological Availability; Biotransformation; Blood Proteins; Captopril; Chromatography, Thin Layer; Ethylmaleimide; Feces; Half-Life; Humans; Injections, Intravenous; Male; Protein Binding; Random Allocation; Reference Values	1990
Preclinical pharmacology of zofenopril, an inhibitor of angiotensin I converting enzyme. Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Availability; Blood Pressure; Captopril; Dogs; Female; Ileum; In Vitro Techniques; Macaca fascicularis; Male; Muscle Contraction; Rats	1989
Peripheral hemodynamic and humoral effects of oral zofenopril calcium (SQ. 26,991) in patients with congestive heart failure. Journal of clinical pharmacology, 1989, Volume: 29, Issue:12 Topics: Administration, Oral; Aged; Angiotensin I; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Captopril; Female; Forearm; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Renin; Vasodilation; Veins	1989
The increase in coronary flow induced by converting enzyme inhibitors is prostacyclin independent. Progress in clinical and biological research, 1989, Volume: 301 Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Circulation; Enalaprilat; Epoprostenol; In Vitro Techniques; Indomethacin; Male; Rats; Rats, Inbred Strains	1989
Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE). British journal of clinical pharmacology, 1989, Volume: 28 Suppl 2 Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Bridged Bicyclo Compounds; Captopril; Chemotherapy, Cancer, Regional Perfusion; Dose-Response Relationship, Drug; Enalapril; Fosinopril; Heart; Hypertension; Lisinopril; Male; Organophosphorus Compounds; Proline; Ramipril; Rats; Time Factors; Tissue Distribution	1989
The future of angiotensin-converting enzyme inhibitors. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Binding Sites; Captopril; Diuretics; Fosinopril; Humans; Intestinal Absorption; Kinetics; Organophosphorus Compounds; Renin; Snake Venoms; Zinc	1985
Simultaneous determination of the prodrug zofenopril and its active drug in plasma by capillary gas chromatography-mass-selective detection. Journal of chromatography, 1988, Jun-24, Volume: 428, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Biotransformation; Captopril; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Methylation; Prodrugs	1988
Zofenopril after anterior myocardial infarction. The New England journal of medicine, 1995, Jun-22, Volume: 332, Issue:25 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Myocardial Infarction	1995
Zofenopril after anterior myocardial infarction. The New England journal of medicine, 1995, Jun-22, Volume: 332, Issue:25 Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Humans; Myocardial Infarction	1995
Zofenopril after anterior myocardial infarction. The New England journal of medicine, 1995, Jun-22, Volume: 332, Issue:25 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Heart Failure; Humans; Myocardial Infarction	1995
[Utilization of angiotensin-converting enzyme inhibitors in anterior infarction without congestive semiology]. Revista espanola de cardiologia, 1995, Volume: 48, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Myocardial Infarction	1995
ACE inhibition in acute myocardial infarction. The New England journal of medicine, 1995, Jan-12, Volume: 332, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Myocardial Infarction	1995
Temperature, pH and agitation rate as dissolution test discriminators of zofenopril calcium tablets. Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:2 Topics: Captopril; Hydrogen-Ion Concentration; Prodrugs; Solubility; Tablets; Temperature	1994
Cardioprotection in ischemic rat hearts with the SH-containing angiotensin-converting enzyme inhibitor zofenopril: possible involvement of the ATP-sensitive potassium channel. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2 Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Coronary Vessels; Male; Myocardial Contraction; Myocardial Ischemia; Potassium Channels; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Stereoisomerism	1993
Equipotent antihypertensive agents variously affect pulsatile hemodynamics and regression of cardiac hypertrophy in spontaneously hypertensive rats. Circulation, 1996, Dec-01, Volume: 94, Issue:11 Topics: Animals; Antihypertensive Agents; Captopril; Cardiomegaly; Hemodynamics; Hydralazine; Hypertension; Male; Pulsatile Flow; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Remission Induction; Ventricular Function, Left; Water	1996
[ACE inhibitors with SH groups have no effect of ATP-dependent K channels--a dissertation]. Acta medica Austriaca, 1996, Volume: 23, Issue:3 Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cattle; Coronary Vessels; Culture Techniques; Glyburide; Guinea Pigs; Muscle, Smooth, Vascular; Potassium Channels; Structure-Activity Relationship; Vasoconstriction; Vasodilation	1996
Intestinal absorption of captopril and two thioester analogs in rats and dogs. Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biotransformation; Captopril; Chromatography, Thin Layer; Dogs; Female; Humans; Intestinal Absorption; Male; Prodrugs; Rats; Rats, Sprague-Dawley; Species Specificity	1997
KATP channel opening does not contribute significantly to the vasodilatory effect of SH-group-containing ACE inhibitors. Heart and vessels, 1996, Volume: 11, Issue:4 Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Captopril; Cattle; Coronary Vessels; Endothelium, Vascular; Glyburide; Guinea Pigs; Hypoglycemic Agents; In Vitro Techniques; Muscle, Smooth, Vascular; Potassium Channels; Sulfhydryl Compounds; Vasodilation	1996
Effects of sulphydryl- and non-sulphydryl-containing ACE inhibitors on left ventricular relaxation in the isolated guinea pig heart. Endothelium : journal of endothelial cell research, 1997, Volume: 5, Issue:4 Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diastole; Female; Free Radical Scavengers; Guinea Pigs; Heart Ventricles; Hemoglobins; Isoquinolines; Lisinopril; Male; Muscle Relaxation; Nitric Oxide; Receptor, Bradykinin B2; Simethicone; Stroke Volume; Sulfhydryl Compounds; Superoxide Dismutase; Systole; Tetrahydroisoquinolines; Ventricular Dysfunction, Left	1997
Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter. Pharmaceutical research, 1999, Volume: 16, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Captopril; Carrier Proteins; Cell Membrane; Dipeptides; Dose-Response Relationship, Drug; Enalapril; Fosinopril; Isoquinolines; Kidney; Kinetics; Lipid Metabolism; Lipids; Lisinopril; Male; Microvilli; Peptide Transporter 1; Quinapril; Rabbits; Ramipril; Symporters; Tetrahydroisoquinolines	1999
Beneficial effects of ACE-inhibition with zofenopril on plaque formation and low-density lipoprotein oxidation in watanabe heritable hyperlipidemic rabbits. General pharmacology, 1999, Volume: 33, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Blood Platelets; Captopril; Female; Hyperlipoproteinemia Type II; Immunohistochemistry; Lipoproteins, LDL; Male; Rabbits	1999
Regression of myocardial fibrosis in hypertensive heart disease: diverse effects of various antihypertensive drugs. Cardiovascular research, 2000, Volume: 46, Issue:2 Topics: Animals; Antihypertensive Agents; Captopril; Collagen; Fibrosis; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Labetalol; Male; Myocardium; Nifedipine; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric	2000
Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure. British journal of pharmacology, 2000, Volume: 130, Issue:8 Topics: Acetylcholine; Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Calcimycin; Captopril; Endothelium, Vascular; Heart Diseases; In Vitro Techniques; Lisinopril; Male; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Sodium Nitrite; Sulfhydryl Compounds; Vasodilation; Vasodilator Agents	2000
Assay of zofenopril and its active metabolite zofenoprilat by liquid chromatography coupled with tandem mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications, 2000, Dec-01, Volume: 749, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Calibration; Captopril; Chromatography, Liquid; Drug Stability; Humans; Mass Spectrometry; Quality Control; Reference Standards; Reproducibility of Results	2000
Cardioprotective effects of zofenopril, a new angiotensin-converting enzyme inhibitor, on doxorubicin-induced cardiotoxicity in the rat. European journal of pharmacology, 2001, Feb-23, Volume: 414, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents; Body Weight; Captopril; Cardiotonic Agents; Doxorubicin; Drug Therapy, Combination; Electrocardiography; Female; Heart; Hemodynamics; Isoproterenol; Male; Mice; Mice, Nude; Organ Size; Ovarian Neoplasms; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2001
Chronic treatment with sulfhydryl angiotensin-converting enzyme inhibitors reduce susceptibility of plasma LDL to in vitro oxidation, formation of oxidation-specific epitopes in the arterial wall, and atherogenesis in apolipoprotein E knockout mice. International journal of cardiology, 2001, Volume: 81, Issue:2-3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Stenosis; Apolipoproteins E; Arteries; Arteriosclerosis; Blood Pressure; Captopril; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Epitopes; Immunohistochemistry; Lipid Peroxidation; Lipoproteins, LDL; Male; Mice; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Peptidyl-Dipeptidase A; Random Allocation; Sulfhydryl Reagents; Time Factors; Treatment Outcome	2001
Zofenopril inhibits the expression of adhesion molecules on endothelial cells by reducing reactive oxygen species. American journal of hypertension, 2002, Volume: 15, Issue:10 Pt 1 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cell Adhesion Molecules; Cells, Cultured; E-Selectin; Endothelium, Vascular; Glutathione; Humans; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; NF-kappa B; Reactive Oxygen Species; Superoxides; Umbilical Veins; Vascular Cell Adhesion Molecule-1	2002
An unusual rearrangement of Zofenopril, a new ACE inhibitor drug: mass spectrometric and conformational studies. Journal of mass spectrometry : JMS, 2002, Volume: 37, Issue:12 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Mass Spectrometry; Molecular Structure; Pharmaceutical Preparations	2002
Cardioprotective effect of zofenopril in perfused rat heart subjected to ischemia and reperfusion. Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Heart Rate; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar	2004
Dietary sodium restriction specifically potentiates left ventricular ACE inhibition by zofenopril, and is associated with attenuated hypertrophic response in rats with myocardial infarction. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2004, Volume: 5, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Diet, Sodium-Restricted; Heart Ventricles; Hypertrophy, Left Ventricular; In Vitro Techniques; Kidney; Male; Myocardial Infarction; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Ventricular Function, Left	2004
Effects of angiotensin-converting-enzyme inhibitors in combination with diuretics on blood pressure and renal injury in nitric oxide-deficiency-induced hypertension in rats. Clinical science (London, England : 1979), 2006, Volume: 110, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Diuretics; Drug Therapy, Combination; Enalapril; Hydrochlorothiazide; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine	2006
Hydrochlorothiazide increases plasma or tissue angiotensin-converting enzyme-inhibitor drug levels in rats with myocardial infarction: differential effects on lisinopril and zofenopril. European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Creatinine; Drug Therapy, Combination; Heart Ventricles; Hydrochlorothiazide; Hypertrophy, Left Ventricular; Kidney; Kidney Function Tests; Lisinopril; Male; Myocardial Infarction; Peptidyl-Dipeptidase A; Prodrugs; Rats; Rats, Sprague-Dawley; Ventricular Function	2005
An Angiotensin-converting enzyme inhibitor, zofenopril, prevents renal ischemia/reperfusion injury in rats. Annals of clinical and laboratory science, 2006,Summer, Volume: 36, Issue:3 Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Female; Kidney; Kidney Tubules; Oxidative Stress; Rats; Renal Circulation; Reperfusion Injury; Statistics, Nonparametric	2006
[ACE inhibitors after myocardial infarction: close-up on zofenopril]. Annales de cardiologie et d'angeiologie, 2007, Volume: 56, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic	2007
The evolution of ACE inhibition--a turning point in cardiovascular medicine. Blood pressure. Supplement, 2007, Volume: 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Controlled Clinical Trials as Topic; History, 20th Century; History, 21st Century; Humans; Hypertension; Myocardial Infarction	2007
Effects of zofenopril on cardiac sarcoplasmic reticulum calcium handling. Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; Gene Expression; Heart; Hemodynamics; In Vitro Techniques; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sarcoplasmic Reticulum	2009
Cardiovascular changes in spontaneously hypertensive rats are improved by chronic treatment with zofenopril. British journal of pharmacology, 2009, Volume: 158, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; Cardiomegaly; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluorometry; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY	2009
HPLC-DAD method for the simultaneous determination of zofenopril and hydrochlorothiazide in oral pharmaceutical formulations. Journal of separation science, 2010, Volume: 33, Issue:12 Topics: Angiotensin-Converting Enzyme Inhibitors; Calibration; Captopril; Chromatography, High Pressure Liquid; Diuretics; Hydrochlorothiazide; Limit of Detection; Pharmaceutical Preparations; Reference Standards; Reproducibility of Results	2010
Aliskiren, a renin inhibitor, downregulates TNF-α-induced tissue factor expression in HUVECS. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2010, Volume: 11, Issue:4 Topics: Amides; Captopril; Down-Regulation; Endothelial Cells; Fumarates; Humans; Imidazoles; Renin; Tetrazoles; Thromboplastin; Tumor Necrosis Factor-alpha; Umbilical Veins	2010
Differences between zofenopril and ramipril, two ACE inhibitors, on cough induced by citric acid in guinea pigs: role of bradykinin and PGE2. Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 382, Issue:5-6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Bronchoalveolar Lavage Fluid; Captopril; Citric Acid; Cough; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Male; Ornithine; Ramipril; Sulfonamides	2010
Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits. Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4 Topics: Anesthesia, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Citric Acid; Consciousness; Cough; Drug Evaluation, Preclinical; Injections, Intravenous; Male; Rabbits; Ramipril; Reflex	2010
Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of zofenopril and its active metabolite zofenoprilat in human plasma. Journal of pharmaceutical and biomedical analysis, 2011, Jun-01, Volume: 55, Issue:3 Topics: Calibration; Captopril; Chromatography, High Pressure Liquid; Drug Stability; Humans; Indicators and Reagents; Limit of Detection; Molecular Structure; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry	2011
Effect of acute and chronic zofenopril administration on cardiac gene expression. Molecular and cellular biochemistry, 2011, Volume: 352, Issue:1-2 Topics: Animals; Base Sequence; Captopril; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Male; Myocardium; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction	2011
The anti-oxidant and anti-apoptotic effects of nebivolol and zofenopril in a model of cerebral ischemia/reperfusion in rats. Progress in neuro-psychopharmacology & biological psychiatry, 2012, Jan-10, Volume: 36, Issue:1 Topics: Animals; Antioxidants; Apoptosis; Benzopyrans; Brain Ischemia; Captopril; Cerebral Cortex; Disease Models, Animal; Ethanolamines; Female; Nebivolol; Oxidants; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome	2012
Protective effects of zofenopril on testicular torsion and detorsion injury in rats. Urology journal, 2011,Fall, Volume: 8, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Male; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Testis	2011
Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. Pharmacological research, 2012, Volume: 65, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Captopril; Drug Synergism; Enalapril; Female; Fosinopril; Male; Mice; Motor Activity; Seizures	2012
Cardioprotective effects of zofenopril, enalapril and valsartan against ischaemia/reperfusion injury as well as doxorubicin cardiotoxicity. Acta cardiologica, 2012, Volume: 67, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Doxorubicin; Enalapril; Heart Diseases; Hemodynamics; Humans; Male; Rats; Rats, Wistar; Reperfusion Injury; Tetrazoles; Valine; Valsartan	2012
Simultaneous estimation and validation of some binary mixtures of antihypertensive drugs by RP-LC methods using two new generation silica columns. Journal of pharmaceutical and biomedical analysis, 2013, Volume: 72 Topics: Antihypertensive Agents; Captopril; Chromatography, Reverse-Phase; Hydrochlorothiazide; Imidazoles; Indicators and Reagents; Silicon Dioxide; Solvents; Tetrazoles	2013
[Efficacy of ACE-inhibitors in patients with recent myocardial infarction. Studies with zofenopril]. Giornale italiano di cardiologia (2006), 2012, Volume: 13, Issue:10 Suppl 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Myocardial Infarction; Time Factors	2012
LC-MS/MS characterization of forced degradation products of zofenopril. Journal of pharmaceutical and biomedical analysis, 2014, Volume: 88 Topics: Antihypertensive Agents; Captopril; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Stability; Hydrolysis; Limit of Detection; Oxidative Stress; Oxygen; Photolysis; Reproducibility of Results; Tandem Mass Spectrometry; Temperature	2014
Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition. Cardiovascular research, 2014, Apr-01, Volume: 102, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Captopril; Cystathionine gamma-Lyase; Hydrogen Sulfide; Male; Rats, Inbred SHR; Rats, Inbred WKY	2014
Determination of zofenopril and its active metabolite in human plasma using high-performance liquid chromatography combined with a triple-quadruple tandem mass spectrometer. Journal of chromatographic science, 2015, Volume: 53, Issue:2 Topics: Adult; Captopril; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Linear Models; Male; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Young Adult	2015
Effects of treatment with zofenopril in men and women with acute myocardial infarction: gender analysis of the SMILE Program. PloS one, 2014, Volume: 9, Issue:11 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Female; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Sex Factors; Treatment Outcome	2014
Zofenopril attenuates injury induced by ischemia-reperfusion on rat ovary. The journal of obstetrics and gynaecology research, 2015, Volume: 41, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Biomarkers; Captopril; Catalase; Dose-Response Relationship, Drug; Female; Malondialdehyde; Ovarian Diseases; Ovary; Oxidative Stress; Protein Carbonylation; Random Allocation; Rats, Wistar; Reperfusion Injury; Torsion, Mechanical	2015
Derivative spectrophotometric method for simultaneous determination of zofenopril and fluvastatin in mixtures and pharmaceutical dosage forms. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Sep-05, Volume: 148 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Dosage Forms; Drug Combinations; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Limit of Detection; Spectrophotometry; Spectrophotometry, Ultraviolet	2015
Zofenopril and Ramipril in Combination with Acetyl Salicylic Acid in Postmyocardial Infarction Patients with Left Ventricular Systolic Dysfunction: A Retrospective Analysis of the SMILE-4 Randomized, Double-Blind Study in Diabetic Patients. Cardiovascular therapeutics, 2016, Volume: 34, Issue:2 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Cardiovascular Diseases; Diabetic Cardiomyopathies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ramipril; Randomized Controlled Trials as Topic; Retrospective Studies; Systole; Ventricular Dysfunction, Left	2016
Zofenopril Protects Against Myocardial Ischemia-Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability. Journal of the American Heart Association, 2016, 07-05, Volume: 5, Issue:7 Topics: Animals; Antihypertensive Agents; Biological Availability; Blotting, Western; Captopril; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Heart; Hydrogen Sulfide; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Ramipril; Random Allocation; Regional Blood Flow; Reverse Transcriptase Polymerase Chain Reaction; Sulfurtransferases; Swine; Swine, Miniature; Troponin I	2016
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition. The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:11 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hydroxyproline; Hypertension; Male; Myocardium; Rats, Wistar; Superoxides; Time Factors; Vasodilation; Vasodilator Agents	2016
The effects of zofenopril on cardiac function and pro-oxidative parameters in the streptozotocin-induced diabetic rat heart. Molecular and cellular biochemistry, 2017, Volume: 426, Issue:1-2 Topics: Animals; Biomarkers; Captopril; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Male; Oxidative Stress; Rats; Rats, Wistar	2017
Early Treatment With Zofenopril and Ramipril in Combination With Acetyl Salicylic Acid in Patients With Left Ventricular Systolic Dysfunction After Acute Myocardial Infarction: Results of a 5-Year Follow-up of Patients of the SMILE-4 Study. Journal of cardiovascular pharmacology, 2017, Volume: 69, Issue:5 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Chi-Square Distribution; Clinical Trials, Phase III as Topic; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Early Medical Intervention; Female; Follow-Up Studies; Hospitalization; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Ramipril; Randomized Controlled Trials as Topic; Recovery of Function; Retrospective Studies; Risk Factors; Systole; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left	2017
A Validated High-Performance Thin-Layer Chromatographic Method for the Simultaneous Determination of Zofenopril Calcium and Hydrochlorothiazide in the Presence of the Hydrochlorothiazide Impurities: Chlorothiazide and Salamide. Journal of AOAC International, 2018, Jul-01, Volume: 101, Issue:4 Topics: Calibration; Captopril; Chlorothiazide; Chromatography, Thin Layer; Drug Combinations; Drug Contamination; Hydrochlorothiazide; Limit of Detection; Sulfonamides; Tablets	2018
A Capillary Zone Electrophoresis Method with Multiresponse Chemometric Optimization for the Simultaneous Determination of Zofenopril Calcium and Hydrochlorothiazide in Presence of Hydrochlorothiazide Major Impurities. Journal of chromatographic science, 2018, May-01, Volume: 56, Issue:5 Topics: Captopril; Drug Combinations; Drug Contamination; Electrophoresis, Capillary; Hydrochlorothiazide; Limit of Detection; Linear Models; Reproducibility of Results	2018
Effect of endostatin and insulin-like growth factor-1 on angiogenesis in patients with acute myocardial infarction with obesity under the influence of zofenopril. Wiadomosci lekarskie (Warsaw, Poland : 1960), 2020, Volume: 73, Issue:1 Topics: Captopril; Endostatins; Humans; Insulin-Like Growth Factor I; Myocardial Infarction; Obesity	2020
Zofenopril: Blood pressure control and cardio-protection. Cardiology journal, 2022, Volume: 29, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diuretics; Humans; Hypertension; Myocardial Ischemia	2022
Can Zofenopril Be the Answer to the Achilles Heel of Vascular Surgery? European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2022, Volume: 63, Issue:2 Topics: Captopril; Humans; Vascular Surgical Procedures	2022
Hydrogen Sulphide Release via the Angiotensin Converting Enzyme Inhibitor Zofenopril Prevents Intimal Hyperplasia in Human Vein Segments and in a Mouse Model of Carotid Artery Stenosis. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2022, Volume: 63, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Carotid Stenosis; Cells, Cultured; Disease Models, Animal; Humans; Hydrogen Sulfide; Hyperplasia; Hypertension; Male; Mice; Myocytes, Smooth Muscle; Organ Culture Techniques; Primary Cell Culture; Tunica Intima; Veins	2022
Extemporaneous combination therapy with nebivolol/zofenopril in hypertensive patients: usage in Italy. Current medical research and opinion, 2022, Volume: 38, Issue:10 Topics: Adult; Aged; Anti-Inflammatory Agents; Antihypertensive Agents; Captopril; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Hypertension; Hypoglycemic Agents; Lipids; Male; Medication Adherence; Nebivolol; Retrospective Studies	2022
The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760. Biological research, 2023, Oct-25, Volume: 56, Issue:1 Topics: Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiovascular System; Essential Hypertension; Humans; Pandemics; Rats; Rats, Inbred SHR	2023