Page last updated: 2024-08-23

captopril and verapamil

captopril has been researched along with verapamil in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (33.72)	18.7374
1990's	34 (39.53)	18.2507
2000's	14 (16.28)	29.6817
2010's	9 (10.47)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Das, AM; Harris, DA	1
Bulpitt, C; Fletcher, A	1
Aronica, A; Carzaniga, G; Catalano, M; Cislaghi, C; Libretti, A; Seregni, R	1
Geller, AL; Goldabin, VI; Goloshchapov, OA; Mashin, AA; Rud', SS	1
Göransson-Nyberg, A; Hansell, P; Sjöquist, M; Ulfendahl, HR	1
Carotenuto, A; De Divitiis, O; Di Somma, S; Liguori, V; Paulucci, A; Petitto, M	1
Clark, R; Gupta, AK; Kirchner, KA	1
Ahonen, A; Riska, H; Salorinne, Y; Sovijärvi, AR; Stenius-Aarniala, B; Sundberg, S	1
Baumgartner, HR; Hefti, F; Kuhn, H; Müller, RK; Powell, JS; Rouge, M	1
Galey-Arcangioli, C; Imbs, JL; Maarek-Charbit, M; Stephan, D; Welsch, M	1
Atlan, JP; Bouche, JM; Ceccaldi, JP; Drici, MD; Giacomoni, S; Halimi, G; Lapalus, P; Morand, P; Passeron-Seître, M; Teboul, B	1
Blantz, RC; De Nicola, L; Gabbai, FB	1
Toshima, H	1
Curry, C; Gray, J; Hollifield, J; Kong, BW; Saunders, E; Schoenberger, J; Sowers, JR; Vertes, V; Weir, MR; Zemel, MB	1
Baume, RM; Croog, SH; Kong, BW; Levine, S; Saunders, E; Weir, MR	1
Ram, CV	1
Eisen, V; Munday, MR; Slater, JD	2
Riska, H; Sovijärvi, AR; Stenius-Aarniala, B	1
Dandona, P; Gill, J; Jeremy, J	1
Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W	1
Littler, WA; Smith, SA	1
Champion, WJ; Navar, LG; Thomas, CE	1
Koster, M	1
Markiewicz, M; Rymar, B; Trojnar, R; Wysokiński, A	1
Anaise, D; Lane, B; Rapaport, FT; Waltzer, WC	1
Barros, EJ; Boim, MA; Draibe, SA; Ramos, OL; Schor, N; Sigulem, D	1
Herman, A; Laekman, G; Lámeire, N; Vanholder, R	1
Ferrara, AL; Marotta, T; Pasanisi, F	1
Heagerty, AM; Swales, JD	1
Ajzen, H; Barros, EJ; Boim, MA; Ramos, OL; Schor, N	1
Riska, H; Sovijärvi, AR; Stenius-Aaniala, B	1
Huang, WC	1
Bean, BL; Loeb, AL	1
Anaise, D; Lane, B; Ramsammy, L; Rapaport, FT; Waltzer, WC	1
García-Iglesias, C; López-Novoa, JM; Macias-Nuñez, JF; Santos, JC; Sanz, E	1
Pflederer, W	1
Anand, MP	1
Johnston, CI	1
Angelini, A; Dario, C; Mazzucato, A; Pauletto, P; Pessina, AC; Scannapieco, G; Semplicini, A; Vescovo, G	1
Brunner, HR; Waeber, B	1
Brunner, HR; Burckhardt, P; Gavras, H; Waeber, B	1
Braunwald, E; Darsee, JR; DeBoer, LW; Ertl, G; Glogar, DH; Ingwall, JS; Kloner, RA	1
Bar-Andziak, E; Chlewicka, I	1
Bozhko, AP; Solodkov, AP	1
Gil-Extremera, B; González-Gómez, L; Luna del Castillo, JD; Maldonado-Martín, A; Rubio-Luengo, MA	1
Ben-Ishay, D; Bursztyn, M; Fidel, J; Ghanem, J; Kobrin, I	1
Collins, TJ; Mehra, MR; Ramee, SR; Smart, FW; Stapleton, DD; Ventura, HO	1
Barbee, RW; Conrad, K; Maymind, M; Zimmerman, R	1
Cohen, EP; Fish, BL; Hill, P; Moulder, JE	1
Drici, MD; Iacono, P; Jacomet, Y; Lapalus, P	1
del Río Pérez, G; Fernández Vidal, P; Garrido García, J; Mora-Macià, J; Ocón Pujadas, J; Velasco Quintana, J	1
Bujor, MA; Davis, BB; Myles, PS; Olenikov, I	1
Arvidsson, N; Herlitz, H; Lukes, D; Mjörnstedt, L; Olausson, M	2
Adachi, K; Hidaka, T; Muraishi, A; Okamoto, T; Seki, Y; Toshima, H	1
Granger, JP; Schnackenberg, CG	1
Brandt, D; Hofmann, R; Magometschnigg, D; Sihorsch, K; Stoschitzky, K; Zangeneh, M; Zenker, G	1
Lopez, R; San Miguel, A; Taboada, C	1
Dal Ponte, DB; Fogt, DL; Henriksen, EJ; Jacob, S	1
Kähönen, M; Kööbi, T; Turjanmaa, V; Ylitalo, P; Ylitalo, R	1
Atucha, NM; Cachofeiro, V; Fortepiani, LA; García-Estañ, J; Lahera, V; Ortíz, MC; Rodrigo, E; Ruilope, LM	1
Jin, ZJ; Qi, JH; Wang, J; Wei, PJ; Zhang, L; Zhang, PJ	1
Cifková, R; Compagnone, D; Hejl, Z; Nakov, R; Novozámská, E; Petrzílková, Z; Poledne, R; Stávek, P	1
Iversen, BM; Myking, O; Ofstad, J; Svarstad, E	1
Alberti, A; Corrada, E; Ferrari, S; Mafrici, A; Marenna, B	1
Ghini, B; Lehfeld, LS; Lopes de Faria, JB; Silveira, LA	1
Dali, MM; Heran, CL; Mathias, NR; Moench, PA; Smith, RL; Stetsko, PI	1
Arnold, N; Marx, G; Rassler, B; Tannapfel, A; Ziegelhöffer-Mihalovicova, B; Zimmer, HG	1
Eiger, G; Goldberg, S; Patel, NP; Pugh, ME	1

Reviews

7 review(s) available for captopril and verapamil

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Quality of life in the treatment of hypertension. The effect of calcium antagonists. Drugs, 1992, Volume: 44 Suppl 1 Topics: Calcium Channel Blockers; Captopril; Humans; Hypertension; Male; Nifedipine; Propranolol; Quality of Life; Verapamil	1992
Calcium antagonists in the treatment of hypertension. The American journal of the medical sciences, 1985, Volume: 290, Issue:3 Topics: Biological Transport, Active; Calcium; Calcium Channel Blockers; Captopril; Diltiazem; Diuretics; Drug Resistance; Drug Therapy, Combination; Electrophysiology; Humans; Hypertension; Hypertension, Renovascular; Ion Channels; Kinetics; Methyldopa; Muscle, Smooth, Vascular; Nifedipine; Propranolol; Sodium; Vascular Resistance; Verapamil	1985
Antihypertensive agents--the race for third place. Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2 Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil	1985
Hypertension--drug management. The Journal of the Association of Physicians of India, 1982, Volume: 30, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Diazoxide; Humans; Hypertension; Indoramin; Labetalol; Minoxidil; Nifedipine; Nitroprusside; Prazosin; Sympatholytics; Vasodilator Agents; Verapamil	1982
[New therapeutic approaches to arterial hypertension]. Schweizerische medizinische Wochenschrift, 1982, Sep-25, Volume: 112, Issue:39 Topics: Angiotensin II; Benzothiadiazines; Calcium; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hyperkalemia; Hypertension; Nifedipine; Renin-Angiotensin System; Sodium; Sodium Chloride Symporter Inhibitors; Vasodilation; Verapamil	1982

Trials

17 trial(s) available for captopril and verapamil

Article	Year
Effects of treatment with verapamil SR and captopril on the lipid profile of hypertensive patients. Drugs, 1992, Volume: 44 Suppl 1 Topics: Blood Pressure; Captopril; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Lipid Metabolism; Lipids; Male; Middle Aged; Verapamil	1992
Antihypertensive effects of verapamil, captopril and their combination at rest and during dynamic exercise. Arzneimittel-Forschung, 1992, Volume: 42, Issue:2 Topics: Aged; Antihypertensive Agents; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Exercise; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Rest; Verapamil	1992
Effects of captopril on blood pressure and respiratory function compared to verapamil in patients with hypertension and asthma. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:1 Topics: Aged; Asthma; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Peak Expiratory Flow Rate; Respiration; Respiratory Function Tests; Verapamil; Vital Capacity	1990
[Comparison of the efficacy and tolerability of sustained-release verapamil and captopril in mild to moderate essential arterial hypertension]. Annales de cardiologie et d'angeiologie, 1991, Volume: 40, Issue:8 Topics: Adult; Captopril; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Verapamil	1991
[Comparative efficacy of sustained release verapamil and captopril in mild to moderate arterial hypertension by ambulatory measurement and occasional measurement]. Annales de cardiologie et d'angeiologie, 1991, Volume: 40, Issue:9 Topics: Adult; Aged; Ambulatory Care; Blood Pressure Determination; Blood Pressure Monitors; Captopril; Delayed-Action Preparations; Double-Blind Method; Humans; Hypertension; Middle Aged; Verapamil	1991
A comparison of the efficacy and safety of a beta-blocker, a calcium channel blocker, and a converting enzyme inhibitor in hypertensive blacks. Archives of internal medicine, 1990, Volume: 150, Issue:8 Topics: Adult; Aged; Atenolol; Black People; Captopril; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Renin; Supination; Verapamil	1990
Hypertensive black men and women. Quality of life and effects of antihypertensive medications. Black Hypertension Quality of Life Multicenter Trial Group. Archives of internal medicine, 1990, Volume: 150, Issue:8 Topics: Age Factors; Antihypertensive Agents; Atenolol; Black or African American; Black People; Captopril; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Quality of Life; Randomized Controlled Trials as Topic; Sex Factors; Verapamil	1990
Comparison of the effects of an angiotensin converting enzyme inhibitor and a calcium channel blocker on blood pressure and respiratory function in patients with hypertension and asthma. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10 Topics: Aged; Asthma; Blood Pressure; Captopril; Double-Blind Method; Electrocardiography; Female; Forced Expiratory Volume; Humans; Hypertension; Male; Middle Aged; Peak Expiratory Flow Rate; Random Allocation; Respiration; Verapamil	1987
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 1 Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil	1985
Comparison of the efficacy of an ACE-inhibitor and a calcium channel blocker in hypertensive asthmatics. A preliminiary report. Postgraduate medical journal, 1986, Volume: 62 Suppl 1 Topics: Aged; Asthma; Captopril; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Random Allocation; Verapamil	1986
Variations in magnesium and zinc in hypertensive patients receiving different treatments. American journal of hypertension, 1995, Volume: 8, Issue:7 Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Cholesterol, HDL; Erythrocytes; Female; Humans; Hypertension; Magnesium; Male; Middle Aged; Time Factors; Verapamil; Zinc	1995
Comparison of verapamil and captopril in elderly hypertensive subjects: results of a randomized, double-blind, crossover study. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:1 Topics: Aged; Analysis of Variance; Blood Pressure; Captopril; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Verapamil	1993
Is verapamil also a non-selective beta blocker? International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:1 Topics: Adrenergic beta-Antagonists; Blood Pressure; Captopril; Cell Membrane; Double-Blind Method; Heart Rate; Humans; Hypertension; Lymphocytes; Radioligand Assay; Receptors, Adrenergic, beta; Single-Blind Method; Up-Regulation; Verapamil	1993
[A clinical study of the verapamil and captopril combination in hypertensive patients uncontrolled by monotherapy. An evaluation by recording the 24-hour ambulatory blood pressure]. Medicina clinica, 1993, Apr-10, Volume: 100, Issue:14 Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Blood Pressure Monitors; Captopril; Circadian Rhythm; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Verapamil	1993
Treatment of left ventricular hypertrophy in hypertensive patients with a combination of verapamil and captopril--a multicenter study. International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:9 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Verapamil	1997
Influence of captopril, propranolol, and verapamil on arterial pulse wave velocity and other cardiovascular parameters in healthy volunteers. International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:9 Topics: Adult; Antihypertensive Agents; Arteries; Blood Pressure; Captopril; Cardiac Output; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Male; Propranolol; Pulsatile Flow; Pulse; Respiratory Mechanics; Verapamil	1998
Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension. Journal of human hypertension, 2000, Volume: 14, Issue:6 Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Confidence Intervals; Cross-Over Studies; Delayed-Action Preparations; Drug Combinations; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Lipoproteins; Male; Middle Aged; Treatment Outcome; Vasodilator Agents; Verapamil	2000

Other Studies

62 other study(ies) available for captopril and verapamil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Mitochondrial ATP synthase regulation in heart: defects in hypertension are restored after treatment with captopril. Cardioscience, 1992, Volume: 3, Issue:4 Topics: Animals; Captopril; Cardiotonic Agents; Cells, Cultured; Electric Stimulation; Hypertension; Isoproterenol; Male; Mitochondria, Heart; Multienzyme Complexes; Myocardium; NADH, NADPH Oxidoreductases; Proton-Translocating ATPases; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ruthenium Red; Verapamil	1992
[Comparative study of the action of Finoptin, Korinfar and Capoten in patients with stage II hypertensive disease]. Kardiologiia, 1992, Volume: 32, Issue:5 Topics: Adult; Aged; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nifedipine; Verapamil	1992
Tubuglomerular feedback control in long-looped nephrons. Topical minireview. Upsala journal of medical sciences, 1992, Volume: 97, Issue:2 Topics: Animals; Captopril; Feedback; Glomerular Filtration Rate; Juxtaglomerular Apparatus; Kidney Concentrating Ability; Kidney Medulla; Nephrons; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Verapamil	1992
Verapamil prevents insulin antinatriuresis in euglycemic rats. The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 2 Topics: Animals; Blood Glucose; Captopril; Insulin; Insulin Antagonists; Male; Natriuresis; Osmolar Concentration; Rats; Rats, Inbred Strains; Reference Values; Sodium; Verapamil	1992
The proliferative response to vascular injury is suppressed by angiotensin-converting enzyme inhibition. Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 4 Topics: Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Northern; Captopril; Cell Division; Cilazapril; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Matrix; Growth Substances; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Pyridazines; Rats; Verapamil	1990
Renal functional reserve in treated and untreated hypertensive rats. Kidney international, 1991, Volume: 40, Issue:3 Topics: Animals; Captopril; Glycine; Hypertension, Renovascular; Kidney Function Tests; Kidney Glomerulus; Male; Punctures; Rats; Rats, Inbred Strains; Renal Circulation; Verapamil	1991
[Progress in the treatment of myocardial diseases]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Mar-10, Volume: 79, Issue:3 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Diltiazem; Echocardiography; Electrocardiography; Female; Humans; Male; Middle Aged; Verapamil	1990
Effects of angiotensin I converting enzyme inhibition and calcium channel blockade on plasma levels of active and inactive renin in conscious rabbits. Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14 Topics: Angiotensin Amide; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Captopril; Consciousness; Feedback; Ion Channels; Juxtaglomerular Apparatus; Rabbits; Renin; Secretory Rate; Verapamil	1987
Captopril inhibits the influx of calcium into platelets. European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1 Topics: Blood Platelets; Calcimycin; Calcium; Calcium Radioisotopes; Captopril; Epinephrine; Humans; In Vitro Techniques; Verapamil	1989
Effects of calcium channel blockade on renal vascular resistance responses to changes in perfusion pressure and angiotensin-converting enzyme inhibition in dogs. Circulation research, 1986, Volume: 58, Issue:6 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Dogs; Female; Kidney; Male; Nifedipine; Vascular Resistance; Verapamil	1986
[Calcium channel blockers and angiotensin converting enzyme inhibitors in the treatment of high blood pressure]. Nederlands tijdschrift voor geneeskunde, 1986, Aug-23, Volume: 130, Issue:34 Topics: Calcium Channel Blockers; Captopril; Drug Interactions; Enalapril; Humans; Hypertension; Nifedipine; Oligopeptides; Teprotide; Verapamil	1986
Role of kininase II (ACE; E.C.3.4.15.1) in the regulation of renin secretion. Advances in experimental medicine and biology, 1986, Volume: 198 Pt A Topics: Angiotensin II; Animals; Captopril; Homeostasis; Kinetics; Peptidyl-Dipeptidase A; Rabbits; Renin; Renin-Angiotensin System; Verapamil	1986
[Effect of the treatment with captopril and verapamil on left-ventricular function in patients with primary arterial hypertension]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1988, Feb-29, Volume: 43, Issue:9 Topics: Adult; Captopril; Female; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Verapamil	1988
The protective effect of calcium inhibitors and of captopril on the renal microcirculation during reperfusion. Transplantation, 1987, Volume: 43, Issue:1 Topics: Angiotensin II; Animals; Calcium; Captopril; Dogs; Heparin; Kidney; Kidney Cortex; Kidney Glomerulus; Kidney Transplantation; Mannitol; Microcirculation; Organ Preservation; Perfusion; Trifluoperazine; Verapamil	1987
Effects of cyclosporin on renal microcirculation. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1987, Volume: 2, Issue:4 Topics: Animals; Captopril; Cyclosporins; Glomerular Filtration Rate; Indomethacin; Kidney Glomerulus; Microcirculation; Rats; Rats, Inbred Strains; Renal Circulation; Renin-Angiotensin System; Verapamil	1987
Influence of vasoactive substances on early toxic acute renal failure in the dog. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1987, Volume: 2, Issue:5 Topics: Acute Kidney Injury; Animals; Captopril; Dogs; Glomerular Filtration Rate; Imidazoles; Mercuric Chloride; Prostaglandins; Renal Circulation; Renin-Angiotensin System; Thromboxane B2; Time Factors; Verapamil	1987
A combination of verapamil, captopril, and diuretic in the treatment of severe hypertension. Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:2 Topics: Adult; Captopril; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Verapamil	1988
The combination of verapamil and captopril in the treatment of essential hypertension. Pharmatherapeutica, 1987, Volume: 5, Issue:1 Topics: Captopril; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Verapamil	1987
Glomerular hemodynamics and hormonal participation on cyclosporine nephrotoxicity. Kidney international, 1987, Volume: 32, Issue:1 Topics: Animals; Captopril; Cyclosporins; Glomerular Filtration Rate; Hemodynamics; Hormones; Indomethacin; Kidney Glomerulus; Male; Rats; Rats, Brattleboro; Rats, Inbred Strains; Verapamil	1987
Effects of verapamil alone and with captopril on blood pressure and bilateral renal function in Goldblatt hypertensive rats. Clinical science (London, England : 1979), 1986, Volume: 70, Issue:5 Topics: Animals; Blood Pressure; Captopril; Glomerular Filtration Rate; Hypertension, Renovascular; Kidney; Male; Potassium; Rats; Rats, Inbred Strains; Sodium; Urodynamics; Verapamil	1986
Antihypertensive drugs inhibit hypertension-associated aortic DNA synthesis in the rat. Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:12 Topics: Animals; Antihypertensive Agents; Captopril; DNA; Female; Hydralazine; Hypertension; Hypertension, Renal; Male; Muscle, Smooth, Vascular; Rats; Verapamil	1986
The pathophysiology of the no-reflow phenomenon in cold-stored kidneys. Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 2 Topics: Animals; Calcium; Captopril; Cold Temperature; Dogs; Kidney; Renal Circulation; Tissue Preservation; Trifluoperazine; Verapamil	1987
Influence of plasma renin content, intrarenal angiotensin II, captopril, and calcium channel blockers on the vasoconstriction and renin release promoted by adenosine in the kidney. The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:5 Topics: Adenosine; Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Diet, Sodium-Restricted; Dogs; Extracellular Space; Female; Kidney; Male; Propranolol; Renal Circulation; Renin; Vasoconstriction; Verapamil	1985
[Therapy of cardiomyopathies]. Fortschritte der Medizin, 1982, Aug-26, Volume: 100, Issue:31-32 Topics: Adrenergic beta-Agonists; Anti-Arrhythmia Agents; Anticoagulants; Captopril; Cardiac Glycosides; Cardiomyopathies; Diet, Sodium-Restricted; Digitoxin; Digoxin; Dihydralazine; Diuretics; Humans; Nitrates; Practolol; Prenalterol; Temperance; Vasodilator Agents; Verapamil	1982
New antihypertensive drugs. Angiotensin converting enzyme inhibitors and calcium antagonists. Australian family physician, 1984, Volume: 13, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Verapamil	1984
[Evaluation of the efficacy of various hypotensive drugs in broad-breasted white turkeys as an experimental model of arterial hypertension with high catecholamine levels]. Bollettino della Societa italiana di biologia sperimentale, 1983, Sep-30, Volume: 59, Issue:9 Topics: Animals; Antihypertensive Agents; Captopril; Catecholamines; Disease Models, Animal; Furosemide; Hypertension; Labetalol; Male; Oxprenolol; Rats; Turkeys; Verapamil	1983
Hypertension in a patient with hypercalcemia: captopril and verapamil. Archives of internal medicine, 1982, Volume: 142, Issue:1 Topics: Adult; Captopril; Drug Therapy, Combination; Female; Humans; Hypercalcemia; Hyperparathyroidism; Hypertension; Proline; Spironolactone; Verapamil	1982
Observations on the experimental reduction of infarct size and on the delayed consequences of transient myocardial ischemia. Acta medica Scandinavica. Supplementum, 1981, Volume: 651 Topics: Animals; Captopril; Dogs; Fluorocarbons; Flurbiprofen; Myocardial Infarction; Myocardium; Necrosis; Verapamil	1981
[New hypotensive drugs]. Kardiologia polska, 1981, Volume: 24, Issue:10 Topics: Antihypertensive Agents; Captopril; Drug Evaluation; Guanfacine; Guanidines; Humans; Hypertension; Labetalol; Minoxidil; Nifedipine; Phenylacetates; Saralasin; Verapamil	1981
[Effect of endogenous metabolites on autoregulation and dilational reserve of coronary vessels]. Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:5 Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Captopril; Coronary Circulation; Coronary Vessels; Eicosanoids; Female; In Vitro Techniques; Indomethacin; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Vasodilation; Verapamil	1993
An intravascular ultrasound study of the influence of angiotensin-converting enzyme inhibitors and calcium entry blockers on the development of cardiac allograft vasculopathy. The American journal of cardiology, 1995, Apr-15, Volume: 75, Issue:12 Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Coronary Disease; Diltiazem; Enalapril; Female; Heart Transplantation; Humans; Hyperplasia; Lisinopril; Male; Middle Aged; Nifedipine; Transplantation, Homologous; Tunica Intima; Ultrasonography, Interventional; Verapamil	1995
Effect of verapamil and captopril on endothelial injury in the diabetic hypertensive rat. American journal of hypertension, 1994, Volume: 7, Issue:7 Pt 1 Topics: Animals; Blood Pressure; Blood Vessels; Body Weight; Captopril; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypertension; Male; Myocardium; Rats; Rats, Wistar; Tunica Media; Verapamil	1994
Prophylaxis of experimental bone marrow transplant nephropathy. The Journal of laboratory and clinical medicine, 1994, Volume: 124, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bone Marrow Transplantation; Captopril; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enalapril; Kidney; Kidney Diseases; Male; Proteinuria; Radiation Injuries, Experimental; Rats; Time Factors; Uremia; Verapamil; Whole-Body Irradiation	1994
ACE-inhibitors, calcium antagonists and low systemic vascular resistance following cardiopulmonary bypass. A case-control study. The Medical journal of Australia, 1993, May-17, Volume: 158, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Cardiopulmonary Bypass; Case-Control Studies; Coronary Artery Bypass; Critical Care; Diltiazem; Dopamine; Enalapril; Female; Heart Valves; Humans; Length of Stay; Male; Middle Aged; Nifedipine; Norepinephrine; Retrospective Studies; Single-Blind Method; Syndrome; Vascular Resistance; Verapamil	1993
Rat heart allograft survival after treatment with verapamil, captopril, and enalapril. Transplantation proceedings, 1995, Volume: 27, Issue:6 Topics: Animals; Captopril; Drug Interactions; Enalapril; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous; Verapamil	1995
Induction of DNA breaks in cardiac myoblast cells by norepinephrine. Biochemistry and molecular biology international, 1996, Volume: 38, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Captopril; DNA; DNA Damage; DNA, Single-Stranded; Heart; Hydrogen Peroxide; Myocardium; Norepinephrine; Propranolol; Quinazolines; Rats; Stimulation, Chemical; Verapamil	1996
Verapamil abolishes the preglomerular response to ANG II during intrarenal nitric oxide synthesis inhibition. The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 2 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Captopril; Dogs; Enzyme Inhibitors; Kidney; Kidney Glomerulus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Regional Blood Flow; Vascular Resistance; Verapamil	1997
Metabolic effects in rats of verapamil alone and in combination with captopril. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 118, Issue:2 Topics: Alanine Transaminase; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Glucose; Calcium; Calcium Channel Blockers; Captopril; Glucose; Intestinal Absorption; Lipids; Male; Potassium; Rats; Rats, Sprague-Dawley; Verapamil	1997
Interactions of captopril and verapamil on glucose tolerance and insulin action in an animal model of insulin resistance. Metabolism: clinical and experimental, 1998, Volume: 47, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Calcium Channel Blockers; Captopril; Disease Models, Animal; Drug Interactions; Female; Glucose; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Oxidation-Reduction; Phosphorylation; Rats; Rats, Zucker; Verapamil	1998
Prolonged rat heart allograft survival after treatment with angiotensin converting enzyme inhibitor or a calcium antagonist. Scandinavian journal of urology and nephrology, 1998, Volume: 32, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Captopril; Drug Therapy, Combination; Enalapril; Female; Graft Survival; Heart Transplantation; Immunosuppression Therapy; Male; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous; Verapamil	1998
Pressure natriuresis in nitric oxide-deficient hypertensive rats: effect of antihypertensive treatments. Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Verapamil	1999
Effects of captopril and enalaprilat on intracellular Ca2+, Na+ contents and pH in hypoxic and reoxygenated cardiomyocytes. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Calcium Channel Blockers; Captopril; Cell Hypoxia; Enalaprilat; Hydrogen-Ion Concentration; Myocardium; Rats; Rats, Wistar; Sodium; Verapamil	1997
Effect of light exercise on renal hemodynamics in patients with hypertension and chronic renal disease. Scandinavian journal of urology and nephrology, 2002, Volume: 36, Issue:6 Topics: Adult; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Captopril; Enalapril; Exercise; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Norepinephrine; Renal Circulation; Renal Plasma Flow, Effective; Verapamil	2002
Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases. Italian heart journal : official journal of the Italian Federation of Cardiology, 2003, Volume: 4, Issue:12 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antimetabolites, Antineoplastic; Atrial Fibrillation; Captopril; Chest Pain; Colorectal Neoplasms; Coronary Angiography; Digoxin; Disease Management; Echocardiography; Electrocardiography; Fluorouracil; Humans; Laryngeal Neoplasms; Middle Aged; Myocardial Infarction; Nitrates; Verapamil	2003
Early blood pressure normalization independent of the class of antihypertensive agent prevents augmented renal fibronectin and albuminuria in experimental diabetic nephropathy. Kidney & blood pressure research, 2004, Volume: 27, Issue:2 Topics: Albuminuria; Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Synergism; Fibronectins; Glomerular Filtration Rate; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Verapamil	2004
A rabbit model for sublingual drug delivery: comparison with human pharmacokinetic studies of propranolol, verapamil and captopril. Journal of pharmaceutical sciences, 2006, Volume: 95, Issue:1 Topics: Administration, Sublingual; Animals; Captopril; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Models, Animal; Propranolol; Rabbits; Verapamil	2006
Effects of salt loading and various therapies on cardiac hypertrophy and fibrosis in young spontaneously hypertensive rats. Life sciences, 2006, Jul-24, Volume: 79, Issue:9 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Cardiomegaly; Collagen; Eating; Fibrosis; Hemodynamics; Lung; Male; Myocardium; Nuclease Protection Assays; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA; Sodium Chloride; Verapamil	2006
Hyperinsulinemic euglycemia therapy for verapamil poisoning: case report. American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2007, Volume: 16, Issue:5 Topics: Antidotes; Captopril; Critical Care; Drug Combinations; Female; Glyburide; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Middle Aged; Poisoning; Treatment Outcome; United States; Verapamil	2007