Page last updated: 2024-08-23

captopril and telmisartan

captopril has been researched along with telmisartan in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (9.38)18.2507
2000's7 (21.88)29.6817
2010's20 (62.50)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bender, A; Czobor, P; Jelinek, B; Málnási-Csizmadia, A; Peragovics, Á; Simon, Z; Tombor, L; Végner, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Entzeroth, M; Wienen, W1
Haigh, RM; Redemann, N; van Meel, JC1
Amann, K; Bohlender, J; Drab, M; Ganten, D; Wagner, J; Wienen, W1
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA1
Atkinson, J; Chan, SL; Chillon, JM; Kwan, YW; Perrin-Sarrado, C; Vincent, JM1
Aznaouridis, KA; Karatzis, EN; Lekakis, JP; Papamichael, CM; Protogerou, AD; Stamatelopoulos, KS1
Abdel-Rahim, SR; Ashour, OM; El-Bitar, HI; Gomaa, W; Ibrahim, MA; Ibrahim, YF1
Brody, R; Grossman, E; Peleg, E; Sharabi, Y1
Hara, Y; Hoshino, Y; Kosaka, N; Okada, M; Yamawaki, H1
Kochi, T; Kubota, M; Moriwaki, H; Ohno, T; Sakai, H; Shimizu, M; Tanaka, T; Tsurumi, H; Yasuda, Y1
Fouad, AA; Jresat, I1
Czuczwar, SJ; Jakubus, T; Janowska, A; Lukawski, K; Raszewski, G1
Balam-Salazar, LB; Cardona-Muñoz, EG; Curiel-Beltrán, JA; de Jesús Romero-Prado, MM; Miramontes-Espino, MV; Rios-Arellano, A1
Akcilar, R; Aras, B; Bayat, Z; Kocak, C; Kocak, FE; Metineren, MH; Simsek, H; Yucel, M1
Abdelrahman, AM; Ibrahim, SA; Kelleni, MT1
Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M1
Awwad, ZM; El-Ganainy, SO; El-Khatib, AS; ElMallah, AI; Khattab, MM1
Cortés-Sanabria, L; Cueto-Manzano, AM; Cueto-Ramírez, AM; González-Plascencia, J; Martín-Del-Campo, F; Martínez-Martínez, P; Montañez-Fernández, JL; Ordaz-Medina, EJ; Ordaz-Medina, SM; Rojas-Campos, E; Trujillo-Hernández, B1

Reviews

2 review(s) available for captopril and telmisartan

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for captopril and telmisartan

ArticleYear
Acute effects of renin-angiotensin system blockade on arterial function in hypertensive patients.
    Journal of human hypertension, 2007, Volume: 21, Issue:8

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blood Pressure; Brachial Artery; Captopril; Double-Blind Method; Female; Forearm; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Quinapril; Regional Blood Flow; Telmisartan; Tetrahydroisoquinolines

2007
Dietary flavonoids added to pharmacological antihypertensive therapy are effective in improving blood pressure.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 117, Issue:1

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Benzoates; Biomarkers; Blood Pressure; C-Reactive Protein; Cacao; Candy; Captopril; Combined Modality Therapy; Diet; Female; Flavonoids; Fruit; Humans; Hypertension; Leptin; Lipids; Male; Malus; Mexico; Middle Aged; Tea; Telmisartan; Time Factors; Treatment Outcome; Young Adult

2015
Randomized, double-blinded, controlled clinical trial of the effect of captopril, telmisartan and their combination on systemic inflammation of patients on hemodialysis.
    Scientific reports, 2022, 10-20, Volume: 12, Issue:1

    Topics: Biomarkers; C-Reactive Protein; Captopril; Double-Blind Method; Humans; Inflammation; Interleukin-6; Renal Dialysis; Telmisartan; Tumor Necrosis Factor-alpha

2022

Other Studies

27 other study(ies) available for captopril and telmisartan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching.
    Journal of medicinal chemistry, 2013, Nov-14, Volume: 56, Issue:21

    Topics: Algorithms; Angiotensin-Converting Enzyme Inhibitors; Animals; CHO Cells; Cricetulus; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Molecular Conformation; Molecular Targeted Therapy; Peptidyl-Dipeptidase A; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship; Substrate Specificity

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effects on binding characteristics and renal function of the novel, non-peptide angiotensin II antagonist BIBR277 in the rat.
    Journal of hypertension, 1994, Volume: 12, Issue:2

    Topics: Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Benzoates; Blood Pressure; Captopril; Diuresis; Furosemide; Glomerular Filtration Rate; In Vitro Techniques; Indomethacin; Kidney; Male; Perfusion; Rats; Rats, Wistar; Receptors, Angiotensin; Telmisartan

1994
Hypotensive effects of the angiotensin II antagonist telmisartan in conscious chronically-instrumented transgenic rats.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Captopril; Heart Rate; Imidazoles; Losartan; Rats; Telmisartan; Tetrazoles

1996
Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:2

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Captopril; Cerebrovascular Disorders; Gene Expression; Hypertension; Kidney; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Telmisartan

1998
Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril.
    Journal of hypertension, 2001, Volume: 19, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Captopril; Decerebrate State; Electric Stimulation; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Synaptic Transmission; Telmisartan; Tetrazoles

2001
Constrictor and dilator effects of angiotensin II on cerebral arterioles.
    Stroke, 2005, Volume: 36, Issue:12

    Topics: Angiotensin II; Animals; Arterioles; Benzimidazoles; Benzoates; Calcium Channel Blockers; Captopril; Cerebral Arteries; Dose-Response Relationship, Drug; Imidazoles; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Telmisartan; Tetraethylammonium; Vasoconstriction; Vasodilation

2005
Angiotensin-converting enzyme inhibition and angiotensin AT(1)-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity.
    Pharmacological research, 2009, Volume: 60, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibiotics, Antineoplastic; Benzimidazoles; Benzoates; Captopril; Doxorubicin; Glutathione; Glutathione Peroxidase; Heart; Kidney; Lipid Peroxidation; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Superoxide Dismutase; Telmisartan

2009
Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs.
    American journal of hypertension, 2009, Volume: 22, Issue:10

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Captopril; Hydrochlorothiazide; Losartan; Mice; Nifedipine; RNA, Messenger; Telmisartan

2009
Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:9

    Topics: Animals; Benzimidazoles; Benzoates; Captopril; Drug Therapy, Combination; Fibrosis; Gene Expression Regulation, Enzymologic; Isoproterenol; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Random Allocation; Rats; Rats, Wistar; Telmisartan; Ventricular Dysfunction, Left

2010
Renin-angiotensin system inhibitors suppress azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice.
    Biochemical and biophysical research communications, 2011, Jun-24, Volume: 410, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Azoxymethane; Benzimidazoles; Benzoates; Captopril; Colonic Neoplasms; Cyclooxygenase 2; Deoxyguanosine; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; Oxidative Stress; Plasminogen Activator Inhibitor 1; Precancerous Conditions; Renin-Angiotensin System; RNA, Messenger; Telmisartan; Tumor Necrosis Factor-alpha

2011
Captopril and telmisartan treatments attenuate cadmium-induced testicular toxicity in rats.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Cadmium; Cadmium Chloride; Cadmium Poisoning; Captopril; Caspase 3; Fas Ligand Protein; Glutathione; Lipid Peroxidation; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Random Allocation; Rats; Rats, Sprague-Dawley; Selenium; Telmisartan; Testicular Diseases; Testis; Testosterone; Tumor Necrosis Factor-alpha; Zinc

2013
Combined treatment with gabapentin and drugs affecting the renin-angiotensin system against electroconvulsions in mice.
    European journal of pharmacology, 2013, Apr-15, Volume: 706, Issue:1-3

    Topics: Amines; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Avoidance Learning; Benzimidazoles; Benzoates; Brain; Captopril; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroshock; Enalapril; Gabapentin; gamma-Aminobutyric Acid; Losartan; Male; Mice; Motor Skills; Seizures; Telmisartan

2013
Effects of captopril, telmisartan and bardoxolone methyl (CDDO-Me) in ischemia-reperfusion-induced acute kidney injury in rats: an experimental comparative study.
    Clinical and experimental pharmacology & physiology, 2016, Volume: 43, Issue:2

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Antioxidants; Apoptosis; Arginine; Benzimidazoles; Benzoates; Captopril; Creatine; Endothelin-1; Gene Expression Regulation; Glutathione Peroxidase; Ischemia; Kidney; Lipocalin-2; Lipocalins; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oleanolic Acid; Proto-Oncogene Proteins; Rats; Rats, Wistar; Reperfusion Injury; Sulfhydryl Compounds; Superoxide Dismutase; Telmisartan; Urea

2016
Effect of captopril and telmisartan on methotrexate-induced hepatotoxicity in rats: impact of oxidative stress, inflammation and apoptosis.
    Toxicology mechanisms and methods, 2016, Volume: 26, Issue:5

    Topics: Animals; Apoptosis; Benzimidazoles; Benzoates; Captopril; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Immunohistochemistry; Liver Function Tests; Male; Methotrexate; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Rats; Telmisartan

2016
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:9

    Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan

2019
Telmisartan and captopril ameliorate pregabalin-induced heart failure in rats.
    Toxicology, 2019, 12-01, Volume: 428

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cyclic AMP-Dependent Protein Kinases; Drug Therapy, Combination; Echocardiography; Heart Failure; Male; Myocardium; Natriuretic Peptide, Brain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Pregabalin; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Telmisartan

2019