captopril has been researched along with simvastatin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Chen, X; Guan, JX; Luo, JD; Zhang, GP; Zhang, WW | 1 |
| Gao, YH; Zhang, M; Zhang, W; Zhang, Y; Zhang, YY; Zhao, YX | 1 |
| Adamcova, M; Bednarova, K; Krajcirovicova, K; Mullerova, M; Paulis, L; Pechanova, O; Pelouch, V; Simko, F | 1 |
| Bolen, MA; Halliburton, SS; Schoenhagen, P | 1 |
| Chen, WQ; Chen, WS; Gao, BR; Guan, XQ; Li, ZZ; Xu, ZY; Yang, K; Zhang, YH | 1 |
| Abdollahifar, MA; Jahanabadi, Z; Noorafshan, A; Shirazi, M; Soltani, MR; Tanideh, N | 1 |
| Adamcova, M; Krajcirovicova, K; Matuskova, J; Paulis, L; Pechanova, O; Pelouch, V; Simko, F | 1 |
| Chen, L; Chen, P; Hu, LQ; Li, HQ; Li, TT; Rong, R; Tang, J; Yin, CS; Zhang, Q | 1 |
| Badreldeen, A; El Amrousy, D; El Razaky, O; El-Bendary, A; Erfan, A | 1 |
1 review(s) available for captopril and simvastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for captopril and simvastatin
| Article | Year |
|---|---|
[Study of diagnostic criteria of intima-media thickening and effects of drugs on peripheral arteries].
Topics: Adult; Aged; Anticholesteremic Agents; Aorta, Thoracic; Arteriosclerosis; Captopril; Carotid Arteries; Carotid Stenosis; Female; Femoral Artery; Humans; Male; Middle Aged; Reference Standards; Simvastatin; Tunica Intima; Tunica Media; Ultrasonography | 2004 |
Comparison of pharmacological and electrical cardioversion in permanent atrial fibrillation after prosthetic cardiac valve replacement: a prospective randomized trial.
Topics: Adult; Amiodarone; Anesthesia, General; Atrial Fibrillation; Captopril; Drug Therapy, Combination; Electric Stimulation; Female; Heart Valve Prosthesis; Humans; Male; Middle Aged; Mitral Valve; Prospective Studies; Simvastatin; Treatment Outcome | 2013 |
Comparative study of the efficacy of captopril, simvastatin, and L-carnitine as cardioprotective drugs in children with type 1 diabetes mellitus: a randomised controlled trial.
Topics: Captopril; Carnitine; Carotid Intima-Media Thickness; Child; Diabetes Mellitus, Type 1; Humans; Pharmaceutical Preparations; Simvastatin | 2021 |
16 other study(ies) available for captopril and simvastatin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Simvastatin inhibits cardiac hypertrophy and angiotensin-converting enzyme activity in rats with aortic stenosis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Blood Pressure; Captopril; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Hypertrophy, Left Ventricular; Organ Size; Peptidyl-Dipeptidase A; Rats; Simvastatin; Time Factors | 1999 |
Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; Hypertrophy, Left Ventricular; Kidney; Male; Melatonin; Mineralocorticoid Receptor Antagonists; NF-kappa B; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Simvastatin; Spironolactone; Ventricular Remodeling | 2009 |
Iterative CT reconstruction of aortic intramural hematoma.
Topics: Amlodipine; Aortic Aneurysm; Aortic Dissection; Captopril; Drug Therapy, Combination; Female; Hematoma; Humans; Hydralazine; Metoprolol; Middle Aged; Multidetector Computed Tomography; Simvastatin; Treatment Outcome | 2011 |
Stereological comparison of the effects of pentoxifylline, captopril, simvastatin, and tamoxifen on kidney and bladder structure after partial urethral obstruction in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Estrogen Antagonists; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Male; Pentoxifylline; Rats; Simvastatin; Tamoxifen; Urethral Obstruction; Urinary Bladder Neck Obstruction | 2014 |
Effects of captopril, spironolactone, and simvastatin on the cardiovascular system of non-diseased Wistar rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Simvastatin; Spironolactone; Ventricular Remodeling | 2015 |
Captopril inhibits maturation of dendritic cells and maintains their tolerogenic property in atherosclerotic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, CD; Aorta; Atherosclerosis; Captopril; Cholesterol; Cytokines; Dendritic Cells; Diet, Atherogenic; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Lipids; Male; Rats, Sprague-Dawley; Simvastatin; T-Lymphocytes, Regulatory | 2015 |