Page last updated: 2024-08-23

captopril and pindolol

captopril has been researched along with pindolol in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's4 (16.00)18.2507
2000's7 (28.00)29.6817
2010's8 (32.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Morphy, R; Rankovic, Z1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lithell, HO1
Basciu, M; Cherchi, A; Pili, G; Sau, F; Seguro, C; Siddi, PP; Tamponi, R1
Breckenridge, AM; Grimmer, SF; Orme, ML; Roberts, DH; Tsao, Y; Winstanley, PA1
Breckenridge, A; McLoughlin, GA; Roberts, DH; Tsao, Y1
Birx, DL; Greenberg, MA1
Vidt, DG1
Corvol, P; Elkik, F; Idatte, JM; Ménard, J1
Thind, GS1
Hansson, L1
Araki, H; Gomita, Y; Kawasaki, H; Mimaki, Y; Nakatsuma, A; Okazaki, M1

Reviews

6 review(s) available for captopril and pindolol

ArticleYear
Designed multiple ligands. An emerging drug discovery paradigm.
    Journal of medicinal chemistry, 2005, Oct-20, Volume: 48, Issue:21

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antihypertensive Agents; Antipsychotic Agents; Chemistry, Pharmaceutical; Dopamine D2 Receptor Antagonists; Drug Design; Humans; Ligands; Metabolic Diseases; Peroxisome Proliferator-Activated Receptors; Receptors, Histamine H1; Selective Serotonin Reuptake Inhibitors

2005
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism.
    Diabetes care, 1991, Volume: 14, Issue:3

    Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Lipid Metabolism; Meta-Analysis as Topic; Metoprolol; Pindolol; Propranolol; Prospective Studies

1991
Advances in the medical management of renovascular hypertension.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:3

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Atenolol; Captopril; Dipeptides; Enalapril; Female; Humans; Hypertension, Renovascular; Male; Metoprolol; Middle Aged; Nadolol; Pindolol; Propanolamines; Propranolol; Renal Artery Obstruction; Renin-Angiotensin System; Saralasin; Timolol

1984
Isradipine: a profile in essential hypertension.
    Acta anaesthesiologica Scandinavica. Supplementum, 1993, Volume: 99

    Topics: Animals; Captopril; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Pindolol; Quality of Life

1993

Trials

4 trial(s) available for captopril and pindolol

ArticleYear
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism.
    Diabetes care, 1991, Volume: 14, Issue:3

    Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Lipid Metabolism; Meta-Analysis as Topic; Metoprolol; Pindolol; Propranolol; Prospective Studies

1991
[Electrocardiographic and echocardiographic changes during antihypertensive therapy].
    Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:12

    Topics: Acebutolol; Adolescent; Adult; Aged; Antihypertensive Agents; Captopril; Cardiomegaly; Chlorthalidone; Echocardiography; Electrocardiography; Female; Humans; Hypertension; Indenes; Male; Middle Aged; Nifedipine; Oxprenolol; Pindolol; Propanolamines; Timolol

1990
Haemodynamic effects of atenolol, labetalol, pindolol and captopril: a comparison in hypertensive patients with special reference to changes in limb blood flow, heart rate and left ventricular function.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:2

    Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Captopril; Female; Forearm; Heart; Heart Rate; Hemodynamics; Humans; Hypertension; Labetalol; Leg; Male; Middle Aged; Myocardial Contraction; Pindolol; Regional Blood Flow; Vascular Resistance

1987
Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication.
    Lancet (London, England), 1987, Sep-19, Volume: 2, Issue:8560

    Topics: Atenolol; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Hypertension; Intermittent Claudication; Labetalol; Leg; Male; Middle Aged; Pindolol; Random Allocation

1987

Other Studies

16 other study(ies) available for captopril and pindolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Chronic cough in a 61-year-old female.
    Annals of allergy, 1988, Volume: 61, Issue:2

    Topics: Asthma; Captopril; Cough; Diagnosis, Differential; Female; Humans; Middle Aged; Pindolol

1988
Renal segmental infarction: a cause of reversible malignant hypertension.
    Journal of hypertension, 1984, Volume: 2, Issue:2

    Topics: Adult; Captopril; Diagnosis, Differential; Fibromuscular Dysplasia; Humans; Hypertension, Malignant; Infarction; Kidney; Male; Nephrectomy; Pindolol

1984
Newer antihypertensive agents.
    Comprehensive therapy, 1980, Volume: 6, Issue:3

    Topics: Aged; Antihypertensive Agents; Captopril; Diuretics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Mineralocorticoid Receptor Antagonists; Pindolol; Saralasin; Timolol; United States; Vasoconstrictor Agents

1980
Long-term treatment with angiotensin converting enzyme inhibitor restores reduced calcitonin gene-related peptide-containing vasodilator nerve function in mesenteric artery of spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Captopril; Electric Stimulation; Hydralazine; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Pindolol; Rats; Rats, Inbred SHR; Thiazepines; Time Factors; Vascular Resistance; Vasodilation

1999