captopril has been researched along with phosphoramidon in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (19.32) | 18.7374 |
| 1990's | 49 (55.68) | 18.2507 |
| 2000's | 16 (18.18) | 29.6817 |
| 2010's | 6 (6.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berry, CJ; Fink, CA; Ghai, RD; Qiao, Y; Sakane, Y; Trapani, AJ | 1 |
| Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X | 1 |
| Fustero, S; Lazzari, P; Olimpieri, F; Pani, L; Sanchez-Roselló, M; Tambaro, S; Volonterio, A; Zanda, M | 1 |
| Devi, LA; Fournié-Zaluski, MC; Gagnidze, K; Orng, SV; Ouimet, T; Poras, H; Roques, BP | 1 |
| Conlon, JM; Gao, XP; Koizumi, S; Mayhan, WG; Rennard, SI; Rubinstein, I; Yong, T | 1 |
| Arai, Y; Ghoda, K; Kajita, T; Liu, XF; Matsumiya, T; Ohgiya, N; Oka, T; Taniguchi, T | 1 |
| Nakagawa, M; Nasjletti, A; Stewart, JM; Vavrek, RJ | 1 |
| Kisara, K; Sakurada, S; Sakurada, T; Tan-No, K; Yamada, T | 1 |
| Ando, M; Araki, S; Honda, I; Kohrogi, H; Yamaguchi, T | 1 |
| McDonald, DM; Nadel, JA; Piedimonte, G | 1 |
| Chiyotani, A; Isono, K; Kanemura, T; Konno, K; Sakai, N; Takizawa, T; Tamaoki, J; Yamauchi, F | 1 |
| Fox, AJ; Morton, IK | 1 |
| Barnes, PJ; Chung, KF; Lötvall, JO; Tokuyama, K | 1 |
| Chiyotani, A; Horii, S; Isono, K; Kanemura, T; Kobayashi, K; Sakai, N; Takeuchi, S; Takizawa, T; Tamaoki, J; Yamawaki, I | 1 |
| Fischer, A; Kummer, W | 1 |
| Farmer, SG; Togo, J | 1 |
| Barnes, PJ; Ichinose, M | 1 |
| Endo, S; Ishii, S; Yokosawa, H | 1 |
| Bunnett, NW; Orloff, MS; Turner, AJ | 1 |
| Stimler-Gerard, NP | 1 |
| Danse, MJ; Oblin, A; Zivkovic, B | 1 |
| Bueno, L; Liberge, M; Murillo-Lopez, D; Rivière, PJ | 1 |
| Nakagawa, M; Nasjletti, A | 1 |
| Kuno, Y; Oka, T | 1 |
| Carretero, OA; Erdös, EG; Ura, N | 1 |
| Aoki, K; Hiranuma, T; Ishii, K; Kajiwara, M; Kuno, Y; Matsumiya, T; Oka, T | 1 |
| Gibson, AM; McDermott, JR; Turner, JD | 1 |
| Hiranuma, T; Numata, H; Oka, T | 1 |
| Hájek, I; Syková, E; Teisinger, J | 1 |
| Aoki, K; Kajiwara, M; Oka, T | 1 |
| Cole, T; Conlon, M; Nau, R; Schäfer, G | 1 |
| Borson, DB; Dusser, DJ; Graf, PD; Nadel, JA; Sekizawa, K | 1 |
| Aoki, K; Cui, SY; Ishii, K; Kajiwara, M; Matsumiya, T; Oka, T; Sakamoto, J | 1 |
| Dowdall, MJ; Turner, AJ | 1 |
| Châtelain, C; Lacroix, JS; Pochon, N | 1 |
| Lindell, E; Malm, L; Petersson, G; Svensjö, ME | 1 |
| Adler, M; Deshpande, SS; Sheridan, RE | 1 |
| Laurent, V; Salzet, M | 2 |
| Bertrand, C; Chan, B; Geppetti, P; Massion, P; Nadel, JA; Piedimonte, G; Yamawaki, I | 1 |
| Barnes, PJ; Chung, KF; Kwon, O; Sun, J; Tsukagoshi, H | 1 |
| Brokaw, JJ; White, GW | 1 |
| Battistini, B; Brown, M; Vane, JR | 1 |
| Chiba, Y; Misawa, M | 1 |
| Kishioka, S; Masuda, Y; Miyamoto, Y; Ozaki, M; Yamamoto, H | 1 |
| Anding, P; Gao, XP; Rennard, SI; Robbins, RA; Rubinstein, I | 1 |
| Chiyotani, A; Isono, K; Konno, K; Tamaoki, J | 1 |
| Baker, J; Bertrand, C; Geppetti, P; Nadel, JA; Petersson, G; Piedimonte, G | 1 |
| Bacci, E; McDonald, DM; Nadel, JA; Petersson, G | 1 |
| Katayama, M; McDonald, DM; Nadel, JA; Piedimonte, G | 1 |
| Gao, XP; Olopade, CO; Rubinstein, I; Suzuki, H | 1 |
| Andrén, PE; Caprioli, RM; Nyberg, F; Sanderson, K | 1 |
| Andrén, PE; Caprioli, RM; Eriksson, U; Nyberg, F | 1 |
| D'Orléans-Juste, P; Fournier, A; Lebel, N; Sirois, P | 1 |
| Chakir, M; D'Orléans-Juste, P; Plante, GE | 1 |
| Bourdon, V; Damas, J; Liégeois, JF; Simmons, WH | 1 |
| Ichimura, T; Kashimoto, K; Lindén, A; Nadel, JA; Nagano, Y; Yoshihara, S | 2 |
| Bjorling, DE; Franz, J; Saban, R | 1 |
| Hiranuma, T; Iwao, K; Kitamura, K; Matsumiya, T; Oka, T | 1 |
| Cardell, LO; Kaneko, T; Lindén, A; Nadel, JA; Stjärne, P; Yoshihara, S | 1 |
| Gao, XP; Olopade, CO; Pakhlevaniants, S; Rubinstein, I; Suzuki, H | 1 |
| Akahori, K; Hiranuma, T; Iwao, K; Kanai, M; Kitamura, K; Kobayashi, T; Oka, T; Tamaki, R; Taniguchi, T | 1 |
| Goto, K; Itakura, A; Kikkawa, F; Kondo, I; Kuno, N; Kurauchi, O; Mizutani, S; Ohno, Y; Tomoda, Y | 1 |
| Bunnett, NW; Geppetti, P; Halliday, DA; Kaneko, T; Lovett, M; Nadel, JA; Ricciardolo, FL | 1 |
| Arai, Y; Hiranuma, T; Iwao, K; Kanai, M; Kitamura, K; Oka, T; Taniguchi, T | 1 |
| Fan, XT; Kitamura, K; Oka, T; Taniguchi, T | 1 |
| Baluk, P; Bunnett, NW; McDonald, DM; Murphy, TJ; Thurston, G | 1 |
| Kokkonen, JO; Kovanen, PT; Kuoppala, A; Lindstedt, KA; Saarinen, J | 1 |
| Beresewicz, A; Maczewski, M | 1 |
| Akahori, K; Iwao, K; Kitamura, K; Oka, T; Yano, H | 1 |
| Buljubasich, S; Lau, WA; Pennefather, JN; Ventura, S | 1 |
| Chiba, S; Fukumori, R; Ibusuki, T; Kambe, T; Kubo, T | 1 |
| Bjorling, DE; Jerde, TJ; Nakada, SY; Saban, R | 1 |
| Cardoso, RC; Cyrino, LA; Hackl, LP; Nicolau, M | 1 |
| Jung, CS; Raabe, A; Seifert, V; Vatter, H; Zimmermann, M | 1 |
| Davis, TP; Nemeroff, CB; Ritchie, JC | 1 |
| Marvizón, JC; Song, B | 1 |
| Birklein, F; Krämer, HH; Leis, S; Schmelz, M; Schmidt, K; Sommer, C | 2 |
| Daray, FM; Errasti, AE; Falcioni, AG; Gago, JE; Goldschmidt, ED; Nowak, W; Pelorosso, FG; Pugliese, MI; Rothlin, RP | 1 |
| Jin, XL; Kobayashi, H; Kosaka, K; Oka, T; Takahashi, S; Yoshikawa, M | 1 |
| Akahori, K; Arai, Y; Jin, XL; Kobayashi, H; Kosaka, K; Oka, T; Yoshikawa, M | 1 |
| Blair, AE; Broadley, KJ; Bugert, JJ; Ford, WR; Kidd, EJ | 1 |
| Ahmadiani, A; Arabanian, SA; Balalaie, S; Khalaj, L; Nasoohi, S; Rezaee, Z | 1 |
| Ajimi, J; Ito, K; Ito, M; Kawaguchi, M; Kobayashi, H; Miura, M; Suzuki, T; Takahashi, S; Watanabe, M; Yoshikawa, M | 1 |
| Kawaguchi, M; Kobayashi, H; Murata, T; Suzuki, T; Takahashi, S; Watanabe, M; Yoshikawa, M | 1 |
| Ajimi, J; Kawaguchi, M; Kobayashi, H; Miura, M; Suzuki, T; Takahashi, S; Tsukamoto, H; Yoshikawa, M | 1 |
3 trial(s) available for captopril and phosphoramidon
| Article | Year |
|---|---|
Functional effects of phosphoramidon and captopril on exogenous neuropeptides in human nasal mucosa.
Topics: Adult; Airway Resistance; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Captopril; Drug Synergism; Endothelium, Vascular; Glycopeptides; Humans; Laser-Doppler Flowmetry; Middle Aged; Mucus; Nasal Mucosa; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Substance P; Time Factors; Vasoactive Intestinal Peptide | 1995 |
Inhibition of neutral endopeptidase (NEP) facilitates neurogenic inflammation.
Topics: Adult; Calcitonin Gene-Related Peptide; Captopril; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Female; Glycopeptides; Humans; Hyperalgesia; Immunoenzyme Techniques; Laser-Doppler Flowmetry; Male; Microdialysis; Neprilysin; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Peptidyl-Dipeptidase A; Skin; Time Factors; Vasodilation | 2005 |
Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Calcitonin Gene-Related Peptide; Captopril; Female; Glycopeptides; Humans; Laser-Doppler Flowmetry; Male; Peptidyl-Dipeptidase A; Retrograde Degeneration; Skin; Vasodilation | 2006 |
85 other study(ies) available for captopril and phosphoramidon
| Article | Year |
|---|---|
New alpha-thiol dipeptide dual inhibitors of angiotensin-I converting enzyme and neutral endopeptidase EC 3.4.24.11.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Captopril; Dipeptides; Magnetic Resonance Spectroscopy; Male; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfhydryl Compounds; Thiorphan; Tryptophan | 1995 |
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship | 2008 |
Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Fluorine; Humans; Neprilysin; Peptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Sulfhydryl Compounds | 2009 |
Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay.
Topics: Animals; Aspartic Acid Endopeptidases; Endothelin-Converting Enzymes; Endothelins; Enzyme Assays; Enzyme Inhibitors; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Humans; Metalloendopeptidases; Mice; Organ Specificity; Peptide Library; Peptides; Substrate Specificity | 2010 |
Role of peptidases in bradykinin-induced increase in vascular permeability in vivo.
Topics: Animals; Bradykinin; Capillary Permeability; Captopril; Cheek; Cricetinae; Glycopeptides; Inflammation; Microcirculation; Neprilysin; Peptidyl-Dipeptidase A; Thiorphan | 1992 |
Effects of the subcutaneous administration of enkephalins on tail-flick response and righting reflex of developing rats.
Topics: Aging; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Female; Glycopeptides; Injections, Subcutaneous; Male; Oligopeptides; Pain; Peptides; Posture; Protease Inhibitors; Rats; Rats, Wistar; Reflex | 1992 |
Effects of a kinin antagonist on renal function in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Blood Pressure; Captopril; Desoxycorticosterone; Glomerular Filtration Rate; Glycopeptides; Kallikreins; Kidney; Kinins; Natriuresis; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renal Circulation | 1990 |
Phosphoramidon potentiates mammalian tachykinin-induced biting, licking and scratching behaviour in mice.
Topics: Aggression; Animals; Behavior, Animal; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Injections, Spinal; Leucine; Male; Mice; Mice, Inbred Strains; Neurokinin A; Substance P; Tachykinins | 1990 |
Enkephalinase inhibitor potentiates substance P- and capsaicin-induced bronchial smooth muscle contractions in humans.
Topics: Adult; Aged; Aged, 80 and over; Bronchi; Bronchoconstriction; Capsaicin; Captopril; Drug Synergism; Glycopeptides; Humans; In Vitro Techniques; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Substance P | 1991 |
Neutral endopeptidase and kininase II mediate glucocorticoid inhibition of neurogenic inflammation in the rat trachea.
Topics: Animals; Capillary Permeability; Captopril; Dexamethasone; Endopeptidases; Glycopeptides; Male; Peptidyl-Dipeptidase A; Platelet Activating Factor; Rats; Rats, Inbred Strains; Substance P; Trachea | 1991 |
Effect of neutral endopeptidase inhibition on substance-P-induced increase in short-circuit current of canine cultured tracheal epithelium.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Biological Transport, Active; Captopril; Cells, Cultured; Complement C1; Dogs; Dose-Response Relationship, Drug; Electric Conductivity; Female; Furosemide; Glycopeptides; In Vitro Techniques; Ion Channel Gating; Leucine; Leupeptins; Male; Membrane Potentials; Neprilysin; Substance P; Time Factors; Trachea | 1991 |
An examination of the proposed functional interaction of substance P and 5-HT in the guinea pig ileum.
Topics: Animals; Capsaicin; Captopril; Glycopeptides; Guinea Pigs; Ileum; Leucine; Muscle Contraction; Muscle, Smooth; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Serotonin; Substance P | 1991 |
Bradykinin-induced airway microvascular leakage is potentiated by captopril and phosphoramidon.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Glycopeptides; Guinea Pigs; Lung; Neprilysin; Time Factors | 1991 |
Atrial natriuretic factor inhibits ciliary motility in cultured rabbit tracheal epithelium.
Topics: Animals; Atrial Natriuretic Factor; Captopril; Cells, Cultured; Cilia; Enzyme Inhibitors; Epithelium; Glycopeptides; Indomethacin; Kinetics; Leucine; Leupeptins; Male; Masoprocol; Methylene Blue; Movement; Piroxicam; Purinones; Rabbits; Thiorphan; Trachea | 1991 |
Tissue distribution of neutral endopeptidase 24.11 ('enkephalinase') activity in guinea pig trachea.
Topics: Animals; Bacitracin; Captopril; Enalapril; Epithelium; Female; Glycopeptides; Guinea Pigs; Immunohistochemistry; Neprilysin; Thiorphan; Trachea | 1991 |
Effects of epithelium removal on relaxation of airway smooth muscle induced by vasoactive intestinal peptide and electrical field stimulation.
Topics: Animals; Atropine; Captopril; Electric Stimulation; Endopeptidases; Epithelium; Glycopeptides; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Propranolol; Protease Inhibitors; Thiorphan; Trachea; Vasoactive Intestinal Peptide | 1990 |
The effect of peptidase inhibitors on bradykinin-induced bronchoconstriction in guinea-pigs in vivo.
Topics: 3-Mercaptopropionic Acid; Animals; Asthma; Bradykinin; Bronchoconstriction; Captopril; Glycopeptides; Guinea Pigs; In Vitro Techniques; Lysine Carboxypeptidase; Male; Muscle, Smooth; Propranolol; Protease Inhibitors | 1990 |
Degradation of substance P by the neuroblastoma cells and their membrane.
Topics: Amino Acids; Animals; Captopril; Cell Line; Cell Membrane; Chromatography, High Pressure Liquid; Edetic Acid; Glycopeptides; Mice; Neuroblastoma; Neurons; Peptide Fragments; Substance P; Synaptic Membranes | 1985 |
Catabolism of substance P and neurotensin in the rat stomach wall is susceptible to inhibitors of angiotensin converting enzyme.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Enalapril; Enalaprilat; Gastric Mucosa; Glycopeptides; Kinetics; Male; Neurotensin; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Thermolysin | 1986 |
Neutral endopeptidase-like enzyme controls the contractile activity of substance P in guinea pig lung.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Complement C3; Complement C3a; Complement C5; Complement C5a; Drug Interactions; Endopeptidases; Glycopeptides; Guinea Pigs; Lung; Muscle Contraction; N-Formylmethionine Leucyl-Phenylalanine; Peptidyl-Dipeptidase A; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Thiorphan; Tiopronin; Trachea | 1987 |
Metalloendopeptidase (EC 3.4.24.11) but not angiotensin converting enzyme is involved in the inactivation of substance P by synaptic membranes of the rat substantia nigra.
Topics: Animals; Captopril; Enzyme Activation; Glycopeptides; Hydrolysis; Leucine; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Substrate Specificity; Synaptic Membranes | 1989 |
Opposite central and peripheral control by endogenous opioids of intestinal motility in fed rats.
Topics: Administration, Oral; Animals; Captopril; Electromyography; Endorphins; Enkephalin, Methionine; Gastrointestinal Motility; Glycopeptides; Injections, Intraperitoneal; Injections, Intraventricular; Levallorphan; Male; Naloxone; Rats; Rats, Inbred Strains | 1989 |
Renal function as affected by inhibitors of kininase II and of neutral endopeptidase 24.11 in rats with and without desoxycorticosterone pretreatment.
Topics: Animals; Blood Pressure; Captopril; Desoxycorticosterone; Glomerular Filtration Rate; Glycopeptides; Kidney; Male; Neprilysin; Rats; Rats, Inbred Strains; Reference Values; Sodium Chloride | 1989 |
Estimation of relative importance of three enzymes in the inactivation of [Met5]-enkephalin and [Met5]-enkephalin-Arg6 in three isolated preparations by employing the inhibitor specific for each enzyme.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Methionine; Enkephalins; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Male; Metalloendopeptidases; Mice; Mice, Inbred ICR; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Vas Deferens | 1987 |
Role of renal endopeptidase 24.11 in kinin metabolism in vitro and in vivo.
Topics: 3-Mercaptopropionic Acid; Animals; Bradykinin; Captopril; Glycopeptides; Kidney; Kinins; Lysine Carboxypeptidase; Metalloendopeptidases; Natriuresis; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1987 |
Inactivation of [Leu5]-enkephalin in three isolated preparations: relative importance of aminopeptidase, endopeptidase-24.11 and peptidyl dipeptidase A.
Topics: Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Leucine; Glycopeptides; Guinea Pigs; Hydrolysis; Ileum; Kinetics; Male; Metalloendopeptidases; Mice; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Vas Deferens | 1986 |
Involvement of endopeptidase 24.15 in the inactivation of bradykinin by rat brain slices.
Topics: 4-Aminobenzoic Acid; Animals; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Dynorphins; Endopeptidases; Glycopeptides; Hypothalamus; Leucine; Male; Metalloendopeptidases; Neurotensin; Oligopeptides; para-Aminobenzoates; Peptide Fragments; Phenanthrolines; Rats; Rats, Inbred Strains | 1987 |
Inactivation of dynorphin-(1-8) in isolated preparations by three peptidases.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dynorphins; Glycopeptides; Guinea Pigs; Hypothalamic Hormones; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Neprilysin; Oligopeptides; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits | 1988 |
The effect of opioids and of naloxone on Na+,K+-adenosine triphosphatase activity in frog spinal cord membrane fractions.
Topics: Animals; Captopril; Cell Membrane; Endorphins; Enkephalins; Glycopeptides; Morphine; Naloxone; Rana temporaria; Sodium-Potassium-Exchanging ATPase; Spinal Cord | 1985 |
The inactivation of [Met5]-enkephalin by bestatin-sensitive aminopeptidase, captopril-sensitive peptidyl dipeptidase A and thiorphan-sensitive endopeptidase-24.11 in mouse vas deferens.
Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endopeptidases; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Thiorphan; Tiopronin; Vas Deferens | 1986 |
Specific binding and proteolytic inactivation of bradykinin by membrane vesicles from pig intestinal smooth muscle.
Topics: 5'-Nucleotidase; Animals; Binding Sites; Bradykinin; Captopril; Cell Membrane; Drug Interactions; Enalapril; Endopeptidases; Enzyme Repression; Glycopeptides; In Vitro Techniques; Muscle, Smooth; Nucleotidases; Phenanthrolines; Swine | 1986 |
Neutral endopeptidase and angiotensin converting enzyme inhibitors potentiate kinin-induced contraction of ferret trachea.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Ferrets; Glycopeptides; Kinins; Male; Metalloendopeptidases; Muscle Contraction; Neprilysin; Thiorphan; Tiopronin; Trachea | 1988 |
The enhancing effects of amastatin, phosphoramidon and captopril on the potency of [Met5]-enkephalin in rat vas deferens.
Topics: Animals; Anti-Bacterial Agents; Captopril; Electric Stimulation; Enkephalin, Methionine; Glycopeptides; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Naloxone; Oligopeptides; Peptides; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens | 1986 |
The metabolism of neuropeptides. Both phosphoramidon-sensitive and captopril-sensitive metallopeptidases are present in the electric organ of Torpedo marmorata.
Topics: Animals; Captopril; Cell Membrane; Electric Organ; Endopeptidases; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glycopeptides; Hydrolysis; In Vitro Techniques; Metalloendopeptidases; Nerve Tissue Proteins; Oligopeptides; Phenanthrolines; Torpedo | 1984 |
Tachykinin-induced nasal fluid secretion and plasma exudation in the rat: effects of peptidase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Capillary Permeability; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Male; Nasal Mucosa; Neprilysin; Neurokinin A; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Substance P; Tachykinins | 1995 |
A study of zinc-dependent metalloendopeptidase inhibitors as pharmacological antagonists in botulinum neurotoxin poisoning.
Topics: Amino Acid Sequence; Animals; Botulinum Toxins; Captopril; Diaphragm; Glycopeptides; In Vitro Techniques; Male; Metalloendopeptidases; Mice; Molecular Sequence Data; Neurotoxins; Phrenic Nerve; Protease Inhibitors; Respiratory Paralysis; Zinc | 1995 |
Isolation of a neuropeptide-degrading endopeptidase from the leech Theromyzon tessulatum.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Captopril; Endopeptidases; Enkephalin, Leucine-2-Alanine; Glycopeptides; Hydrolysis; Kinetics; Leeches; Molecular Sequence Data; Molecular Weight; Neuropeptides; Oligopeptides; Protease Inhibitors; Substrate Specificity | 1995 |
Viral infection potentiates the increase in airway blood flow produced by substance P.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Down-Regulation; Glycopeptides; Histamine; Male; Microspheres; Neprilysin; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Inbred F344; Regional Blood Flow; Respiratory System; Substance P | 1995 |
Role of neutral endopeptidase in bronchial hyperresponsiveness to bradykinin induced by IL-1 beta.
Topics: Administration, Inhalation; Animals; Bradykinin; Bronchi; Bronchoalveolar Lavage Fluid; Captopril; Drug Synergism; Glycopeptides; Interleukin-1; Male; Neprilysin; Rats; Recombinant Proteins; Respiratory Hypersensitivity | 1995 |
Differential effects of phosphoramidon and captopril on NK1 receptor-mediated plasma extravasation in the rat trachea.
Topics: Animals; Capillary Permeability; Captopril; Female; Glycopeptides; Neprilysin; Nerve Endings; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptidyl-Dipeptidase A; Protease Inhibitors; Quinuclidines; Rats; Receptors, Neurokinin-1; Tachykinins; Trachea | 1994 |
Selective proteolitic activation and degradation of ETs and big ETs in parenchymal strips of the guinea-pig lung.
Topics: Animals; Captopril; Endopeptidases; Endothelin-1; Endothelins; Glycopeptides; Guinea Pigs; Humans; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Protein Precursors; Structure-Activity Relationship; Swine; Thiorphan | 1995 |
Antigen-induced airway hyperresponsiveness is associated with airway tissue NEP hypoactivity in rats.
Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris suum; Bronchial Hyperreactivity; Capsaicin; Captopril; Enkephalin, Methionine; Glycopeptides; Male; Neprilysin; Peptidyl-Dipeptidase A; Puromycin; Rats; Rats, Wistar; Respiratory System; Specific Pathogen-Free Organisms | 1994 |
Effect of some peptidase inhibitors on exogenous and endogenous opioid actions in guinea-pig ileum.
Topics: Aminopeptidases; Animals; Bacitracin; Captopril; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; Leucine; Male; Morphine; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Thiorphan | 1994 |
Peptidases modulate bradykinin-induced arteriolar dilation in the hamster cheek pouch.
Topics: Animals; Arterioles; Bradykinin; Captopril; Cheek; Cricetinae; Drug Combinations; Endopeptidases; Glycopeptides; Isoproterenol; Male; Mesocricetus; Protease Inhibitors; Vasodilation | 1994 |
[Effect of bradykinin on airway epithelial ion transport and its modulation by endogenous peptidases].
Topics: Animals; Bradykinin; Captopril; Dogs; Dose-Response Relationship, Drug; Endopeptidases; Epithelium; Glycopeptides; In Vitro Techniques; Ion Transport; Lysine Carboxypeptidase; Mercaptoethanol; Trachea | 1993 |
Role of peptidases and NK1 receptors in vascular extravasation induced by bradykinin in rat nasal mucosa.
Topics: Animals; Biphenyl Compounds; Bradykinin; Capillary Permeability; Captopril; Evans Blue; Glycopeptides; Histocytochemistry; Nasal Mucosa; Neprilysin; Peptide Hydrolases; Rats; Rats, Inbred F344; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Urinary Bladder | 1993 |
Neurogenic plasma extravasation in the rat nasal mucosa is potentiated by peptidase inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Capillary Permeability; Capsaicin; Captopril; Endopeptidases; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Glycopeptides; Indoles; Male; Nasal Mucosa; Neprilysin; Organometallic Compounds; Protease Inhibitors; Rats; Rats, Inbred F344; Rhinitis | 1993 |
Peptidase inhibitors reverse steroid-induced suppression of neutrophil adhesion in rat tracheal blood vessels.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Capsaicin; Captopril; Cell Adhesion; Cell Membrane Permeability; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Glycopeptides; Male; Neprilysin; Neutrophils; Rats; Rats, Inbred F344; Trachea | 1993 |
Neutral endopeptidase modulates VIP-induced vasodilation in hamster cheek pouch vessels in situ.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Captopril; Cheek; Cricetinae; Drug Combinations; Glycopeptides; Male; Mesocricetus; Neprilysin; Protease Inhibitors; Thiorphan; Vasoactive Intestinal Peptide; Vasodilation | 1996 |
In vitro metabolism of LVV-hemorphin-7 in human plasma studied by reversed-phase high-performance liquid chromatography and micro-electrospray mass spectrometry.
Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Captopril; Chromatography, High Pressure Liquid; Endorphins; Gas Chromatography-Mass Spectrometry; Glycopeptides; Hemoglobins; Humans; Molecular Sequence Data; Opioid Peptides; Peptide Fragments; Peptides; Plasma; Protease Inhibitors; Spectrophotometry, Ultraviolet; Time Factors | 1996 |
Reversed-phase high-performance liquid chromatography combined with tandem mass spectrometry in studies of a substance P-converting enzyme from human cerebrospinal fluid.
Topics: Animals; Anti-Bacterial Agents; Captopril; Chromatography, Agarose; Chromatography, Gel; Chromatography, High Pressure Liquid; Conductometry; Cross Reactions; Endopeptidases; Gas Chromatography-Mass Spectrometry; Glycopeptides; Humans; Hydrolysis; Immune Sera; Iodine Radioisotopes; Peptide Fragments; Peptides; Protease Inhibitors; Rabbits; Radioimmunoassay; Spectrophotometry, Ultraviolet; Substance P | 1996 |
Role of the neutral endopeptidase 24.11 in the conversion of big endothelins in guinea-pig lung parenchyma.
Topics: Alanine; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin-1; Endothelins; Glycopeptides; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Neprilysin; Protease Inhibitors; Protein Precursors; Thiorphan | 1996 |
Biochemical properties of the angiotensin-converting-like enzyme from the leech Theromyzon tessulatum.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine-2-Alanine; Enzyme-Linked Immunosorbent Assay; Glycopeptides; Hydrogen-Ion Concentration; Hydrolysis; Leeches; Membrane Proteins; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Sodium Chloride; Spectrophotometry, Ultraviolet; Substrate Specificity; Temperature; Time Factors | 1996 |
Neutral endopeptidase inhibition, a new approach in the exploration of diabetic vasculopathy in rats.
Topics: Alanine; Animals; Blood Pressure; Capillary Permeability; Captopril; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Female; Glycopeptides; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Streptozocin; Thiorphan | 1995 |
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.
Topics: Albumins; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Capsaicin; Captopril; Collagenases; Dose-Response Relationship, Drug; Edema; Glycopeptides; Hindlimb; Indoles; Inflammation; Isoindoles; Male; Matrix Metalloproteinase Inhibitors; Methysergide; Neurokinin-1 Receptor Antagonists; Oligopeptides; Organ Size; Protease Inhibitors; Rats; Rats, Wistar; Serotonin Antagonists; Substance P | 1996 |
A novel PACAP 1-27 analogue causes sustained smooth muscle relaxation in guinea-pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Captopril; Glycopeptides; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Protease Inhibitors; Theophylline; Trachea; Vasoactive Intestinal Peptide | 1996 |
Spontaneously released substance P and bradykinin from isolated guinea-pig bladder.
Topics: Animals; Bradykinin; Captopril; Female; Glycopeptides; Guinea Pigs; Muscle Contraction; Peptidyl-Dipeptidase A; Protease Inhibitors; Substance P; Urinary Bladder | 1997 |
Almost complete protection from [Met5]-enkephalin-Arg6-Gly7-Leu8 (Met-enk-RGL) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon.
Topics: Animals; Anti-Bacterial Agents; Captopril; Corpus Striatum; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Kinetics; Male; Morphine; Peptides; Protease Inhibitors | 1997 |
Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro.
Topics: Albuterol; Animals; Bronchi; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs; Macaca fascicularis; Male; Muscle Relaxation; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Trachea | 1997 |
Functional type II VIP-PACAP receptors in human airway epithelial-like cells.
Topics: Captopril; Cyclic AMP; Epithelium; Glycopeptides; Humans; Isoproterenol; Lung; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Protease Inhibitors; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Polypeptide, Type I; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1997 |
Angiotensin-converting enzyme and neutral endopeptidase modulate smokeless tobacco-induced increase in macromolecular efflux from the oral mucosa in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Captopril; Cricetinae; Dextrans; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Glycopeptides; Lisinopril; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Neprilysin; Peptidyl-Dipeptidase A; Plants, Toxic; Protease Inhibitors; Thiorphan; Tobacco, Smokeless | 1997 |
Effects of three peptidase inhibitors, amastatin, captopril and phosphoramidon, on the hydrolysis of [Met5]-enkephalin-Arg6-Phe7 and other opioid peptides.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Enkephalins; Glycopeptides; Guinea Pigs; Hydrolysis; Ileum; Male; Membranes; Opioid Peptides; Peptides; Protease Inhibitors; Visual Cortex | 1998 |
Possible involvement of placental proteases in bradykinin (BK) degradation.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood; Bradykinin; Captopril; Endopeptidases; Female; Glycopeptides; Humans; Hydrolysis; Lysine Carboxypeptidase; Microsomes; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Placenta; Pregnancy | 1997 |
Bradykinin increases intracellular calcium levels in a human bronchial epithelial cell line via the B2 receptor subtype.
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Calcium; Captopril; Cell Line, Transformed; Cyclooxygenase Inhibitors; Epithelial Cells; Glycopeptides; Humans; Indomethacin; Protease Inhibitors; Receptor, Bradykinin B2; Receptors, Bradykinin; Simian virus 40 | 1998 |
Protection against dynorphin-(1-8) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon.
Topics: Animals; Anti-Bacterial Agents; Biotransformation; Captopril; Chromatography, High Pressure Liquid; Dynorphins; Electrochemistry; Glycopeptides; Guinea Pigs; Hydrolysis; Hypothalamic Hormones; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred ICR; Peptide Fragments; Peptides; Protease Inhibitors; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1998 |
Effects of peptidase inhibitors on the enkephalin-induced anti-nociception in rats.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enkephalin, Methionine; Glycopeptides; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 1998 |
Neurogenic plasma leakage in mouse airways.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Blood Vessels; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Captopril; Dose-Response Relationship, Drug; Evans Blue; Glycopeptides; Lung; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Piperidines; Protease Inhibitors; Quinuclidines; Receptors, Neurokinin-2; Skin; Specific Pathogen-Free Organisms; Substance P; Trachea; Urinary Bladder | 1999 |
Kallidin- and bradykinin-degrading pathways in human heart: degradation of kallidin by aminopeptidase M-like activity and bradykinin by neutral endopeptidase.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Bradykinin; Captopril; CD13 Antigens; Dipeptides; Female; Glycopeptides; Heart Failure; Humans; Kallidin; Leucine; Male; Membrane Proteins; Middle Aged; Myocardium; Neprilysin; Peptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Substrate Specificity | 1999 |
The role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Alkaloids; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Aspartic Acid Endopeptidases; Benzophenanthridines; Bosentan; Captopril; Catalase; Coronary Vessels; Endothelin-Converting Enzymes; Endothelins; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Female; Free Radicals; Glycopeptides; Guinea Pigs; Heart; Losartan; Male; Metalloendopeptidases; Muscle Proteins; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitroprusside; Oxidative Stress; Phenanthridines; Prazosin; Protein Kinase C; Reactive Oxygen Species; Sulfonamides; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Vasodilator Agents | 2000 |
Effects of peptidase inhibitors on anti-nociceptive action of dynorphin-(1-8) in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glycopeptides; Injections, Intraventricular; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptide Fragments; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Opioid, mu | 2000 |
Calcitonin gene-related peptide (CGRP) inhibits contractions of the prostatic stroma of the rat but not the guinea-pig.
Topics: Adrenomedullin; Amyloid; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Captopril; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Glyburide; Glycopeptides; Guinea Pigs; Humans; Hypoglycemic Agents; Immunohistochemistry; Islet Amyloid Polypeptide; Leucine; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Peptides; Prostate; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Glycopeptides; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Pepstatins; Peptides, Cyclic; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Renin | 2001 |
In vitro contractile effects of neurokinin receptor blockade in the human ureter.
Topics: Angiotensin-Converting Enzyme Inhibitors; Benzamides; Captopril; Dose-Response Relationship, Drug; Glycopeptides; Humans; Metalloendopeptidases; Muscle Contraction; Piperidines; Receptors, Neurokinin-2; Tachykinins; Ureter | 2001 |
Effect of quercetin on plasma extravasation in rat CNS and dura mater by ACE and NEP inhibition.
Topics: Animals; Capillary Permeability; Captopril; Central Nervous System; Cerebellum; Cerebral Cortex; Dura Mater; Endothelium, Vascular; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Glycopeptides; Jugular Veins; Male; Neprilysin; Neurokinin-1 Receptor Antagonists; Olfactory Bulb; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar; Substance P | 2002 |
Effect of endothelin-converting enzyme inhibitors on big endothelin-1 induced contraction in isolated rat basilar artery.
Topics: Animals; Aspartic Acid Endopeptidases; Basilar Artery; Captopril; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Glycopeptides; Male; Metalloendopeptidases; Protein Precursors; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Vascular Resistance; Vasospasm, Intracranial | 2002 |
Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects.
Topics: Adrenocorticotropic Hormone; Algorithms; Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; CD13 Antigens; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Corticotropin-Releasing Hormone; Glycopeptides; Hypothalamus; In Vitro Techniques; Kinetics; Leucine; Male; Molecular Sequence Data; Neprilysin; Peptidyl-Dipeptidase A; Pituitary Gland; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Thiophenes | 2003 |
Peptidases prevent mu-opioid receptor internalization in dorsal horn neurons by endogenously released opioids.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Endopeptidases; Enzyme Inhibitors; Glycopeptides; In Vitro Techniques; Lumbosacral Region; Narcotic Antagonists; Neprilysin; Opioid Peptides; Peptide Fragments; Peptide Hydrolases; Peptides; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Veratridine | 2003 |
Functional evidence of des-Arg10-kallidin enzymatic inactivating pathway in isolated human umbilical vein.
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; CD13 Antigens; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Glycopeptides; Humans; In Vitro Techniques; Kallidin; Metalloproteases; Neprilysin; Peptides; Protease Inhibitors; Receptor, Bradykinin B1; Umbilical Veins; Vasoconstriction | 2007 |
The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.
Topics: Analgesics; Animals; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Methionine; Glycopeptides; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 2007 |
Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition.
Topics: Animals; Captopril; Drug Synergism; Enkephalin, Leucine; Glycopeptides; Guinea Pigs; Ileum; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Pain; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Vas Deferens | 2008 |
Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity.
Topics: Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Captopril; Cell Count; Glycopeptides; Guinea Pigs; Histamine; Male; Ornithine; Ovalbumin; Parainfluenza Virus 3, Human; Peptides; Plethysmography, Whole Body; Pneumonia; Protease Inhibitors; Respirovirus Infections; Sulfonamides; Tissue Kallikreins | 2010 |
Antinociceptive effect of [Met5]enkephalin semicarbazide is not affected by dipeptidyl carboxypeptidase-I.
Topics: Analgesics; Animals; Biotransformation; Captopril; Carboxypeptidases; Enkephalin, Methionine; Glycopeptides; Hydrolysis; Injections, Spinal; Male; Nociception; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Semicarbazides | 2012 |
Increase in antinociceptive effect of [leu5]enkephalin after intrathecal administration of mixture of three peptidase inhibitors.
Topics: Analgesics; Animals; Captopril; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Enkephalins; Glycopeptides; Injections, Spinal; Male; Nociceptive Pain; Pain Threshold; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 2013 |
Potentiation of [Met5]enkephalin-induced antinociception by mixture of three peptidase inhibitors in rat.
Topics: Analgesics; Animals; Captopril; Drug Synergism; Enkephalin, Methionine; Glycopeptides; Male; Narcotic Antagonists; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 2014 |
Effect of three peptidase inhibitors on antinociceptive potential and toxicity with intracerebroventricular administration of dynorphin A (1-17) or (1-13) in the rat.
Topics: Analgesics; Analgesics, Opioid; Animals; Brain Chemistry; Captopril; Dose-Response Relationship, Drug; Dynorphins; Glycopeptides; Injections, Intraventricular; Male; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Opioid | 2015 |