Page last updated: 2024-08-23

captopril and pentoxifylline

captopril has been researched along with pentoxifylline in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's8 (38.10)29.6817
2010's8 (38.10)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Haustein, UF1
Fartasch, M; Kirchner, T; Mahler, V; Neureiter, D; Schuler, G1
Bakowski, D; Brzyźkiewicz, H; Janion, M1
Amini, M; Aminian, T; Aminorroaya, A; Gharavi, M; Janghorbani, M; Rezvanian, H1
Guerrero-Romero, F; Rodríguez-Morán, M1
Akbari, A; Doucette, S; Fergusson, D; Knoll, G; McCormick, BB; Sydor, A1
Afshariani, R; Banihashemi, MA; Ghezlou, M; Moini, M; Roozbeh, J; Sagheb, MM; Salari, S1
Abdollahifar, MA; Jahanabadi, Z; Noorafshan, A; Shirazi, M; Soltani, MR; Tanideh, N1
Aliev, OI; Anishchenko, AM; Arkhipov, AM; Plotnikov, MB; Shamanaev, AY; Sidekhmenova, AV1
Beltz, TG; Felder, RB; Guo, F; Johnson, AK; Wei, SG; Xue, B; Yu, Y1
Entezari-Maleki, T; Khani, E; Namdar, H; Pourrashid, MH1
Fang, ZQ; Huo, YL; Johnson, AK; Li, JD; Peng, W; Wang, HP; Wang, XF; Xue, B; Zhang, YP1

Reviews

3 review(s) available for captopril and pentoxifylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Current status and trends in treatment of scleroderma].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1992, Volume: 43, Issue:7

    Topics: Captopril; Combined Modality Therapy; Dextrans; Epoprostenol; Humans; Immunosuppressive Agents; Nifedipine; Pentoxifylline; Scleroderma, Systemic

1992
The effect of pentoxifylline on proteinuria in diabetic kidney disease: a meta-analysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:3

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diabetic Nephropathies; Humans; Kidney; Pentoxifylline; Phosphodiesterase Inhibitors; Proteinuria

2008

Trials

4 trial(s) available for captopril and pentoxifylline

ArticleYear
Comparison of the effect of pentoxifylline and captopril on proteinuria in patients with type 2 diabetes mellitus.
    Nephron. Clinical practice, 2005, Volume: 99, Issue:3

    Topics: Adult; Aged; Captopril; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Male; Middle Aged; Pentoxifylline; Proteinuria

2005
Pentoxifylline is as effective as captopril in the reduction of microalbuminuria in non-hypertensive type 2 diabetic patients--a randomized, equivalent trial.
    Clinical nephrology, 2005, Volume: 64, Issue:2

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chi-Square Distribution; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Pentoxifylline; Statistics, Nonparametric; Treatment Outcome

2005
Captopril and combination therapy of captopril and pentoxifylline in reducing proteinuria in diabetic nephropathy.
    Renal failure, 2010, Volume: 32, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chi-Square Distribution; Diabetic Nephropathies; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Pentoxifylline; Proteinuria; Regression Analysis; Treatment Outcome

2010
Effects of Adding Pentoxifylline to Captopril on Primary Hypertension: A Pilot Randomized Clinical Trial.
    Journal of clinical pharmacology, 2020, Volume: 60, Issue:2

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Drug Synergism; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Male; Middle Aged; Pentoxifylline; Pilot Projects; Platelet Aggregation Inhibitors; Single-Blind Method

2020

Other Studies

14 other study(ies) available for captopril and pentoxifylline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[Digital ischemia as paraneoplastic marker of metastatic endometrial carcinoma].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:10

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Captopril; Cystadenocarcinoma, Papillary; Diagnosis, Differential; Endometrial Neoplasms; Female; Fingers; Gangrene; Humans; Ischemia; Paraneoplastic Syndromes; Pentoxifylline; Uterine Neoplasms

1999
[Disturbances of rhythm and atrio-ventricular conduction in digitalis overdose. Case reports].
    Przeglad lekarski, 2001, Volume: 58, Issue:1

    Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atrioventricular Node; Captopril; Digitalis; Digitalis Glycosides; Drug Interactions; Drug Overdose; Drug Therapy, Combination; Female; Heart Conduction System; Humans; Male; Medigoxin; Middle Aged; Pentoxifylline; Plants, Medicinal; Plants, Toxic; Tachycardia, Supraventricular

2001
Stereological comparison of the effects of pentoxifylline, captopril, simvastatin, and tamoxifen on kidney and bladder structure after partial urethral obstruction in rats.
    Korean journal of urology, 2014, Volume: 55, Issue:11

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Estrogen Antagonists; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Male; Pentoxifylline; Rats; Simvastatin; Tamoxifen; Urethral Obstruction; Urinary Bladder Neck Obstruction

2014
Pentoxifylline treatment enhances antihypertensive activity of captopril through hemorheological improvement in spontaneously hypertensive rats during development of arterial hypertension.
    Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:11

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blood Viscosity; Captopril; Cardiac Output; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Erythrocytes; Humans; Hypertension; Pentoxifylline; Platelet Aggregation Inhibitors; Rats; Rats, Inbred SHR; Vascular Resistance

2017
Stress-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Blockade of Angiotensin-Converting Enzyme or Tumor Necrosis Factor-α.
    American journal of hypertension, 2019, 08-14, Volume: 32, Issue:9

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Captopril; Cytokines; Disease Models, Animal; Hypertension; Inflammation Mediators; Male; Microglia; Pentoxifylline; Rats, Long-Evans; Rats, Sprague-Dawley; Renin-Angiotensin System; Stress Disorders, Post-Traumatic; Tumor Necrosis Factor Inhibitors

2019
Blockade of angiotensin-converting enzyme or tumor necrosis factor-α reverses maternal high-fat diet-induced sensitization of angiotensin II hypertension in male rat offspring.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2020, 02-01, Volume: 318, Issue:2

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animal Nutritional Physiological Phenomena; Animals; Antihypertensive Agents; Blood Pressure; Brain; Captopril; Diet, High-Fat; Disease Models, Animal; Female; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Pentoxifylline; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Renin-Angiotensin System; Tumor Necrosis Factor Inhibitors

2020