Page last updated: 2024-08-23

captopril and penicillamine

captopril has been researched along with penicillamine in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199030 (37.97)18.7374
1990's28 (35.44)18.2507
2000's13 (16.46)29.6817
2010's6 (7.59)24.3611
2020's2 (2.53)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Armoush, N; Becker, DP; Gillner, D; Holz, RC1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
de Angelis, E; Grassi, M; Lombardi, ML; Ruocco, V1
De Dobbeleer, G; De Graef, C; Godfrine, S; Gourdain, JM; Heenen, M1
Griffin, JP1
Dahlen, DD; Eary, JF; Evans, ML; Graham, MM; Peterson, LM1
Eyre, RW; Korman, NJ; Stanley, JR; Zone, J1
Coleman, JW1
de Angelis, E; Lombardi, ML; Pisani, M; Ruocco, V1
Paterson, JR; Rumley, AG1
Yeung, JH1
Blanken, R; de Jong, MC; Doeglas, HM; Kardaun, SH; van Leeuwen, M1
Jaeger, P1
Chain, BM; Foreman, JC; Oben, JA; Wallace, GR1
Anhalt, GJ; Hood, AF; Yokel, BK1
Dale, DC; Hammond, WP; Miller, JE; Rosenthal, AS; Starkebaum, G; Zweerink, HJ1
Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Wright, V1
Muirden, KD1
Jaffe, IA3
Hill, GS1
Dunne, M; Molteni, A; Solliday, NH; Ts'ao, CH; Ward, WF1
Mason, RP; Mottley, C; Toy, K1
Adler, SG; Border, WA; Cohen, AH1
Christophidis, N; Drummer, OH; Routley, L1
Coleman, JW; Foster, AL; Park, BK1
Iwata, M; Maruyama, M; Sugiyama, E; Yamashita, N; Yano, S; Yoshikawa, T1
Elling, H; Elling, P1
Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Surrall, KE; Wright, V1
Breckenridge, AM; Park, BK; Yeung, JH1
Andres, GA; Brentjens, JR; Donker, AJ; Venuto, RC; Vladutiu, AO1
Bird, HA; Dixon, JS; Martin, MF; Pickup, ME; Sitton, NG; Surrall, KE1
Pearson, ME; Stechschulte, DJ1
Weening, JJ1
Connolly, SM1
Baudot, N; Fiessinger, JN; Housset, E; Priollet, P; Vayssairat, M1
Antonovych, TT1
Dumler, F1
Clement, M; Parfrey, PS; Vandenburg, MJ; Wright, P1
Gärtner, HV1
Nakajima, M; Shimada, K; Wakabayashi, H; Yamato, S1
Persu, A; Pirson, Y1
Beyersbergen van Henegouwen, GM; van den Broeke, LT1
Molteni, A; Nguyen, L; Ts'ao, CH; Ward, WF1
Belal, F; Eid, MM; Rizk, MS1
De la Lande, IS; Horowitz, JD; Stafford, I; Zhang, CL1
Keire, DA; Mariappan, SV; Peng, J; Rabenstein, DL1
de Angelis, E; Lombardi, ML; Rossano, F; Ruocco, V1
Edmonds, S; Gibb, A; Sim, E1
Aposhian, HV; Maiorino, RM; Xu, ZF1
Correa, JG; Stoppani, AO1
Chow, GK; Streem, SB1
Craven, PA; DeRubertis, FR; Felder, J; Phillips, S; Studer, RK1
Blazsó, G; Gáspár, R1
Metodiewa, D; Winterbourn, CC1
Kim, YT; Molteni, A; Small, W; Taylor, JM; Ts'ao, CH; Ward, WF1
Coe, FL; Nakagawa, Y1
Cársky, J; Hrnciarová, M; Jakus, V; Krahulec, B; Rietbrock, N1
Andersson, RG; Persson, K1
Cheng, HF; Harris, RC; McKanna, JA; Wang, JL; Zhang, MZ1
Andersson, RG; Glindell, M; Jacobsson-Strier, M; Nyhlén, K; Persson, K; Whiss, PA1
Asplin, JR; Clark, C; Coe, FL; Parks, JH1
Dasgupta, T; McGrowder, D; Ragoobirsingh, D1
Kankuri, E; Kotikoski, H; Vapaatalo, H1
Alken, P; Janitzky, V; Knoll, T; Köhrmann, KU; Michel, MS1
Aquart, DV; Dasgupta, TP1
Csiszar, A; Kaminski, PM; Koller, A; Ungvari, Z; Wolin, MS1
Asplin, JR; Dolin, DJ; Flagel, L; Goldfarb, DS; Grasso, M1
Chen, YY; Shen, YL; Wang, Y; Xu, HJ; Zhu, L1
Karakosta, TD; Tzanavaras, PD1
Henderickx, MM; Homan van der Heide, JJ; Kamphuis, GM; Melessen, IM; Merkx, MM; van Etten-Jamaludin, FS1
Aryanian, Z; Daneshpazhooh, M; Etesami, I; Ghaedi, F; Goodarzi, A; Kalantari, Y; Mahmoudi, H; Tavakolpour, S; Teymourpour, A1

Reviews

15 review(s) available for captopril and penicillamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-induced disorders of taste.
    Adverse drug reactions and toxicological reviews, 1992,Winter, Volume: 11, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Captopril; Humans; Metronidazole; Mouth Neoplasms; Penicillamine; Taste Disorders

1992
Allergic reactions to drugs: current concepts and problems.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1990, Volume: 20, Issue:1

    Topics: Antibodies; B-Lymphocytes; Captopril; Drug Hypersensitivity; Humans; Molecular Weight; Penicillamine; Penicillin G; T-Lymphocytes, Helper-Inducer

1990
Cystinuria: pathophysiology and treatment.
    Advances in nephrology from the Necker Hospital, 1989, Volume: 18

    Topics: Captopril; Cystinuria; Humans; Penicillamine; Tiopronin

1989
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
    The Medical journal of Australia, 1986, Jan-06, Volume: 144, Issue:1

    Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical Trials as Topic; Gastrointestinal Diseases; Glomerulonephritis; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Myasthenia Gravis; Myositis; Pemphigus; Penicillamine; Pyrithioxin; Sulfasalazine; Thrombocytopenia

1986
Adverse effects profile of sulfhydryl compounds in man.
    The American journal of medicine, 1986, Volume: 80, Issue:3

    Topics: Anemia, Aplastic; Autoimmune Diseases; Captopril; Drug Eruptions; Glomerulonephritis; Humans; Neutropenia; Penicillamine; Pyridoxine; Pyrithioxin; Stomatitis; Sulfhydryl Compounds; Taste; Thrombocytopenia; Tiopronin

1986
Hypersensitivity phenomena and the kidney: role of drugs and environmental agents.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1985, Volume: 5, Issue:2

    Topics: Animals; Anti-Glomerular Basement Membrane Disease; Anti-Inflammatory Agents; Antibodies; Captopril; Drug Hypersensitivity; Environmental Exposure; Glomerulonephritis; Gold; Heroin; Humans; Hydrocarbons; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immune Complex Diseases; Kidney Diseases; Kidney Glomerulus; Lupus Erythematosus, Systemic; Mercury; Nephritis, Interstitial; Penicillamine; Penicillins; Rifampin

1985
Scleroderma: therapeutic options.
    Cutis, 1984, Volume: 34, Issue:3

    Topics: Alprostadil; Captopril; Colchicine; Griseofulvin; Humans; Immunosuppressive Agents; Nifedipine; Penicillamine; Phenytoin; Physical Therapy Modalities; Plasmapheresis; Prostaglandins E; Scleroderma, Systemic; Vasodilator Agents

1984
[Treatment of systemic scleroderma].
    Annales de dermatologie et de venereologie, 1984, Volume: 111, Issue:6-7

    Topics: Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Colchicine; Factor XIII; Humans; Penicillamine; Plasma Exchange; Prostaglandins; Scleroderma, Systemic

1984
Drug-induced nephropathies.
    Pathology annual, 1984, Volume: 19 Pt 2

    Topics: Allopurinol; Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Captopril; Cephalosporins; Cisplatin; Diuretics; Glomerulonephritis; Gold; Humans; Kidney; Kidney Diseases; Kidney Tubular Necrosis, Acute; Lithium; Nephritis, Interstitial; Penicillamine; Penicillins; Rifampin; Semustine; Sulfonamides; Tetracycline; Trimethadione

1984
Induction of auto-immune syndromes by penicillamine therapy in rheumatoid arthritis and other diseases.
    Springer seminars in immunopathology, 1981, Volume: 4, Issue:2

    Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Captopril; Cystinuria; Hepatolenticular Degeneration; Humans; Penicillamine; Pyrithioxin

1981
[Current aspects of the medical treatment of cystinuria].
    Acta urologica Belgica, 1994, Volume: 62, Issue:2

    Topics: Ascorbic Acid; Captopril; Cystine; Cystinuria; Humans; Hydrogen-Ion Concentration; Penicillamine; Solubility; Tiopronin; Urine

1994
[Cystinuria - Cystine Stones: Recommendations for Diagnosis, Therapy and Follow-up].
    Aktuelle Urologie, 2003, Volume: 34, Issue:2

    Topics: Adult; Age Factors; Angiotensin-Converting Enzyme Inhibitors; Ascorbic Acid; Captopril; Chelating Agents; Child; Cystinuria; Follow-Up Studies; Humans; Kidney Calculi; Lithotripsy; Penicillamine; Time Factors; Tiopronin; Ureteroscopy

2003
The effect of additional drug therapy as metaphylaxis in patients with cystinuria: a systematic review.
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2020, Volume: 72, Issue:4

    Topics: Captopril; Cystine; Cystinuria; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Male; Penicillamine; Tiopronin

2020
Drug-induced pemphigus: A systematic review of 170 patients.
    International immunopharmacology, 2021, Volume: 92

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antirheumatic Agents; Captopril; Cysteine; Drug-Related Side Effects and Adverse Reactions; Humans; Pemphigus; Penicillamine

2021

Trials

5 trial(s) available for captopril and penicillamine

ArticleYear
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
    The Medical journal of Australia, 1986, Jan-06, Volume: 144, Issue:1

    Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical Trials as Topic; Gastrointestinal Diseases; Glomerulonephritis; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Myasthenia Gravis; Myositis; Pemphigus; Penicillamine; Pyrithioxin; Sulfasalazine; Thrombocytopenia

1986
Captopril: a new treatment for rheumatoid arthritis?
    Lancet (London, England), 1984, Jun-16, Volume: 1, Issue:8390

    Topics: Adult; Aged; Arthritis, Rheumatoid; Captopril; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypotension; Male; Middle Aged; Penicillamine; Proline

1984
[Treatment of systemic scleroderma].
    Annales de dermatologie et de venereologie, 1984, Volume: 111, Issue:6-7

    Topics: Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Colchicine; Factor XIII; Humans; Penicillamine; Plasma Exchange; Prostaglandins; Scleroderma, Systemic

1984
Medical treatment of cystinuria: results of contemporary clinical practice.
    The Journal of urology, 1996, Volume: 156, Issue:5

    Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Child, Preschool; Cystinuria; Diuretics; Female; Follow-Up Studies; Humans; Infant; Male; Middle Aged; Penicillamine; Potassium Citrate; Sodium Bicarbonate; Tiopronin; Urinary Calculi

1996
Inhibition of nonenzymatic protein glycation and lipid peroxidation by drugs with antioxidant activity.
    Life sciences, 1999, Volume: 65, Issue:18-19

    Topics: Aged; Antioxidants; Captopril; Depression, Chemical; Diabetes Mellitus, Type 1; Erythrocytes; Glycosylation; Guanidines; Humans; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Middle Aged; Oxidants; Penicillamine; Serum Albumin; Thiobarbituric Acid Reactive Substances

1999

Other Studies

61 other study(ies) available for captopril and penicillamine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity.
    Bioorganic & medicinal chemistry letters, 2009, Nov-15, Volume: 19, Issue:22

    Topics: Amidohydrolases; Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Diaminopimelic Acid; Enzyme Inhibitors; Escherichia coli; Haemophilus influenzae; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Substrate Specificity

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
    Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Enalapril: a powerful in vitro non-thiol acantholytic agent.
    International journal of dermatology, 1992, Volume: 31, Issue:10

    Topics: Acantholysis; Captopril; Culture Techniques; Enalapril; Female; Humans; Immunoglobulin G; Penicillamine; Skin; Time Factors; Tiopronin; Tissue Survival

1992
In vitro acantholysis induced by D-penicillamine, captopril, and piroxicam on dead de-epidermized dermis.
    Journal of cutaneous pathology, 1992, Volume: 19, Issue:3

    Topics: Acantholysis; Captopril; Cell Death; Cells, Cultured; Epidermis; Humans; Keratinocytes; Microscopy, Electron; Models, Biological; Penicillamine; Piroxicam

1992
Vascular response to radiation injury in the rat lung.
    Radiation research, 1992, Volume: 129, Issue:2

    Topics: Animals; Captopril; Cesium Radioisotopes; Cyproheptadine; Dexamethasone; Diethylcarbamazine; Gamma Rays; Lung; Male; Penicillamine; Pulmonary Circulation; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Theophylline

1992
Drug-induced pemphigus: autoantibodies directed against the pemphigus antigen complexes are present in penicillamine and captopril-induced pemphigus.
    The Journal of investigative dermatology, 1991, Volume: 96, Issue:2

    Topics: Aged; Antigen-Antibody Complex; Autoantibodies; Captopril; Female; HLA-DR Antigens; Humans; Male; Middle Aged; Molecular Weight; Pemphigus; Penicillamine

1991
Biochemical acantholysis provoked by thiol drugs.
    Archives of dermatology, 1990, Volume: 126, Issue:7

    Topics: Acantholysis; Captopril; Humans; Pemphigus; Penicillamine; Skin Diseases; Sulfhydryl Compounds; Tiopronin

1990
Drug interference in the measurement of serum fructosamine.
    Annals of clinical biochemistry, 1990, Volume: 27 ( Pt 4)

    Topics: Captopril; Drug Interactions; Fructosamine; Hexosamines; Humans; Penicillamine; Propylthiouracil

1990
Effect of inhibition of glutathione synthesis on the immunogenicity of captopril and captopril-protein conjugates in the mouse.
    Biochemical pharmacology, 1990, Sep-15, Volume: 40, Issue:6

    Topics: Animals; Antibody Formation; Antimetabolites; Buthionine Sulfoximine; Captopril; Glutathione; Immunoglobulin G; Injections, Intraperitoneal; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Penicillamine

1990
Pemphigus-like eruption induced by d-penicillamine and captopril, in the same patient.
    Acta dermato-venereologica, 1988, Volume: 68, Issue:5

    Topics: Captopril; Drug Therapy, Combination; Female; Humans; Middle Aged; Pemphigus; Penicillamine

1988
The stimulation of IL-2 production by anti-rheumatic drugs.
    Immunology, 1989, Volume: 67, Issue:3

    Topics: Animals; Auranofin; Captopril; Cells, Cultured; Interleukin-2; Mice; Penicillamine; Spleen

1989
Induction of acantholysis in organ explant culture by penicillamine and captopril.
    Archives of dermatology, 1989, Volume: 125, Issue:10

    Topics: Acantholysis; Adult; Captopril; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Organ Culture Techniques; Penicillamine; Skin; Skin Diseases; Time Factors

1989
Suppression of in vitro granulocytopoiesis by captopril and penicillamine.
    Experimental hematology, 1988, Volume: 16, Issue:8

    Topics: Animals; Bone Marrow; Captopril; Catalase; Cells, Cultured; Colony-Forming Units Assay; Dogs; Enalapril; Enalaprilat; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukopenia; Oxygen Consumption; Penicillamine; Sulfhydryl Compounds

1988
Biochemical and clinical changes occurring during the treatment of rheumatoid arthritis with novel antirheumatoid drugs.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Viscosity; Captopril; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine; Sulfasalazine; Sulfates; Zinc; Zinc Sulfate

1985
Drug-associated glomerulopathies.
    Toxicologic pathology, 1986, Volume: 14, Issue:1

    Topics: Amyloidosis; Animals; Captopril; Cyclosporins; Disease Models, Animal; Gold; Heroin Dependence; Humans; Hydrocarbons; Immune Complex Diseases; Kidney Diseases; Kidney Glomerulus; Lupus Erythematosus, Systemic; Mercury; Nephrotic Syndrome; Penicillamine; Puromycin Aminonucleoside; Serum Sickness; Solvents; Tetradecanoylphorbol Acetate

1986
Monocrotaline-induced pulmonary fibrosis in rats: amelioration by captopril and penicillamine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:1

    Topics: Animals; Body Weight; Captopril; Hydroxyproline; Lung; Male; Monocrotaline; Organ Size; Penicillamine; Peptidyl-Dipeptidase A; Plants, Toxic; Proline; Pulmonary Fibrosis; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio

1985
Oxidation of thiol drugs and biochemicals by the lactoperoxidase/hydrogen peroxide system.
    Molecular pharmacology, 1987, Volume: 31, Issue:4

    Topics: Acetylcysteine; Captopril; Cysteamine; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydrogen Peroxide; Lactoperoxidase; Oxygen Consumption; Penicillamine; Peroxidases; Sulfhydryl Compounds

1987
Reversibility of disulfide formation. Comparison of chemical and enzyme-mediated reduction of penicillamine and captopril disulfides.
    Biochemical pharmacology, 1987, Apr-15, Volume: 36, Issue:8

    Topics: Animals; Biotransformation; Captopril; Disulfides; Erythrocytes; Glutathione; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Penicillamine; Rats

1987
A specific enzyme-linked immunosorbent assay for definition of the IgG antibody response to disulphide-conjugated D-penicillamine in the rabbit.
    International archives of allergy and applied immunology, 1987, Volume: 84, Issue:3

    Topics: Animals; Antibody Specificity; Captopril; Disulfides; Enzyme-Linked Immunosorbent Assay; Haptens; Immunoglobulin G; Male; Penicillamine; Rabbits; Serum Albumin

1987
Immunosuppression by captopril in vitro: inhibition of human natural killer activity by copper-dependent generation of hydrogen peroxide.
    Japanese journal of medicine, 1986, Volume: 25, Issue:2

    Topics: Captopril; Catalase; Copper; Humans; Hydrogen Peroxide; Immunosuppressive Agents; In Vitro Techniques; Killer Cells, Natural; Penicillamine

1986
Penicillamine, captopril, and hypoglycemia.
    Annals of internal medicine, 1985, Volume: 103, Issue:4

    Topics: Adult; Captopril; Diabetes Mellitus; Female; Humans; Hypoglycemia; Male; Middle Aged; Penicillamine; Proline

1985
Penicillamine, immune complexes, and the kidney.
    Lancet (London, England), 1980, Jul-19, Volume: 2, Issue:8186

    Topics: Antigen-Antibody Complex; Captopril; Humans; Kidney; Penicillamine; Time Factors

1980
Drug protein conjugates--VI. Role of glutathione in the metabolism of captopril and captopril plasma protein conjugates.
    Biochemical pharmacology, 1983, Dec-01, Volume: 32, Issue:23

    Topics: Acetaminophen; Alanine Transaminase; Animals; Ascorbic Acid; Blood Proteins; Captopril; Cysteine; Glutathione; Liver; Male; Mice; Mice, Inbred CBA; Penicillamine; Proline; Protein Binding; Rats; Rats, Inbred Strains

1983
Effects of prolonged administration of D-penicillamine or captopril in various strains of rats. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation.
    Clinical immunology and immunopathology, 1984, Volume: 30, Issue:1

    Topics: Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Basement Membrane; Captopril; Disseminated Intravascular Coagulation; Female; Immunoglobulin G; Kidney Glomerulus; Male; Penicillamine; Proline; Pulmonary Alveoli; Rats; Rats, Inbred BN; Rats, Inbred Lew; Rats, Inbred Strains

1984
The effect of drugs on serum histidine levels in rheumatoid arthritis.
    Rheumatology international, 1983, Volume: 3, Issue:4

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Captopril; Clofibrate; Drug Combinations; Female; Histidine; Humans; Hydroxychloroquine; Male; Middle Aged; Penicillamine; Sulfates; Trientine; Zinc; Zinc Sulfate

1983
Systemic sclerosis.
    The Journal of the Kansas Medical Society, 1984, Volume: 85, Issue:1

    Topics: Adult; Captopril; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Systemic

1984
Autoimmune reactions and glomerulonephritis caused by heavy metals and other toxins.
    Developments in toxicology and environmental science, 1983, Volume: 11

    Topics: Animals; Autoimmune Diseases; Captopril; Glomerulonephritis; Gold; Humans; Mercury; Metals; Penicillamine; Solvents

1983
Drug-induced glomerulopathy: a selective review.
    Henry Ford Hospital medical journal, 1983, Volume: 31, Issue:2

    Topics: Anti-Inflammatory Agents; Captopril; Child; Gold; Humans; Kidney Diseases; Mitomycin; Mitomycins; Penicillamine; Proteinuria; Semustine

1983
Captopril-induced pemphigus.
    British medical journal, 1980, Jul-19, Volume: 281, Issue:6234

    Topics: Captopril; Chemical Phenomena; Chemistry; Humans; Male; Middle Aged; Pemphigus; Penicillamine; Proline

1980
Drug-associated nephropathy. Part I: Glomerular lesions.
    Current topics in pathology. Ergebnisse der Pathologie, 1980, Volume: 69

    Topics: Captopril; Daunorubicin; Gold; Heroin; Humans; Kidney Diseases; Kidney Glomerulus; Mercury; Microscopy, Electron; Penicillamine; Puromycin; Sulfadiazine; Trimethadione

1980
Application of an electrochemical detector with a graphite electrode to liquid chromatographic determination of penicillamine and captopril in biological samples.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:9

    Topics: Administration, Oral; Animals; Captopril; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Graphite; Kidney; Liver; Male; Penicillamine; Rats; Rats, Wistar; Tissue Distribution

1994
UV-radiation protecting efficacy of thiols, studied with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo.
    International journal of radiation biology, 1993, Volume: 63, Issue:4

    Topics: Acetylcysteine; Animals; Captopril; Chlorpromazine; Cysteamine; Epidermis; Ergothioneine; Female; Mesna; Methoxsalen; Penicillamine; Radiation-Protective Agents; Rats; Rats, Wistar; Sulfhydryl Compounds; Tiopronin; Ultraviolet Rays

1993
Captopril inhibits proliferation of human lung fibroblasts in culture: a potential antifibrotic mechanism.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1994, Volume: 205, Issue:1

    Topics: Angiotensin II; Animals; Captopril; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Fibroblasts; Humans; Kinetics; L-Lactate Dehydrogenase; Lung; Mitosis; Penicillamine; Pulmonary Fibrosis; Rats; Thymidine

1994
Conductometric determination of some pharmaceutically important thiol compounds in dosage forms.
    Acta pharmaceutica Hungarica, 1993, Volume: 63, Issue:6

    Topics: Acetylcysteine; Capsules; Captopril; Electrochemistry; Mercaptopurine; Penicillamine; Powders; Sulfhydryl Compounds; Tablets; Thioguanine

1993
S-nitrosothiol modulation of tolerance to glyceryl trinitrate in bovine isolated coronary artery.
    European journal of pharmacology, 1994, Feb-11, Volume: 252, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Captopril; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniques; Nitroglycerin; Nitroso Compounds; Penicillamine; Prostaglandin Endoperoxides, Synthetic; S-Nitroso-N-Acetylpenicillamine; Thromboxane A2; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1994
Nuclear magnetic resonance studies of the binding of captopril and penicillamine by serum albumin.
    Biochemical pharmacology, 1993, Sep-14, Volume: 46, Issue:6

    Topics: Binding, Competitive; Captopril; Cysteine; Disulfides; Humans; Lactates; Magnetic Resonance Spectroscopy; Penicillamine; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Sulfhydryl Compounds

1993
Imbalance between plasminogen activator and its inhibitors in thiol-induced acantholysis.
    Dermatology (Basel, Switzerland), 1993, Volume: 186, Issue:2

    Topics: Acantholysis; Captopril; Culture Media; Culture Techniques; Epidermis; Humans; Penicillamine; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Plasminogen Inactivators; Sulfhydryl Compounds; Tiopronin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

1993
Effect of thiol compounds on human complement component C4.
    The Biochemical journal, 1993, Feb-01, Volume: 289 ( Pt 3)

    Topics: Aminophenols; Binding, Competitive; Captopril; Complement C1s; Complement C4; Complement C4a; Complement C4b; Complement Pathway, Classical; Humans; Isomerism; Penicillamine; Sepharose; Structure-Activity Relationship; Sulfhydryl Compounds

1993
Determination and metabolism of dithiol chelating agents. XVII. In humans, sodium 2,3-dimercapto-1-propanesulfonate is bound to plasma albumin via mixed disulfide formation and is found in the urine as cyclic polymeric disulfides.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Adult; Captopril; Chelating Agents; Chromatography, Thin Layer; Cysteine; Disulfides; Dithiothreitol; Humans; Male; Penicillamine; Protein Binding; Serum Albumin; Unithiol

1996
Catecholamines enhance dihydrolipoamide dehydrogenase inactivation by the copper Fenton system. Enzyme protection by copper chelators.
    Free radical research, 1996, Volume: 24, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding Sites; Captopril; Catecholamines; Catechols; Cattle; Chelating Agents; Copper; Cysteine; Dihydrolipoamide Dehydrogenase; Dopamine; Epinephrine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Mammals; Norepinephrine; Oxidation-Reduction; Oxidopamine; Penicillamine

1996
Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells.
    Diabetes, 1997, Volume: 46, Issue:4

    Topics: Animals; Captopril; Cattle; Cells, Cultured; Coculture Techniques; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glomerular Mesangium; Glucose; Indoles; Maleimides; Nitric Oxide; omega-N-Methylarginine; Osmolar Concentration; Penicillamine; Proline; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Time Factors; Transforming Growth Factor beta; Tritium

1997
[Effects pf captopril and D-penicillamine on kinins-mediated and chronic inflammation].
    Acta pharmaceutica Hungarica, 1996, Volume: 66, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arthritis, Experimental; Bradykinin; Capillaries; Captopril; Dexamethasone; Edema; Immunosuppressive Agents; Kinins; Penicillamine; Rats; Rats, Sprague-Dawley; Vascular Resistance

1996
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.
    Free radical biology & medicine, 1999, Volume: 27, Issue:3-4

    Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Hydrogen Peroxide; Oxygen Consumption; Penicillamine; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxides; Xanthine Oxidase

1999
Mechanism of captopril toxicity to a human mammary ductal carcinoma cell line in the presence of copper.
    Breast cancer research and treatment, 1999, Volume: 55, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Captopril; Carcinoma, Ductal, Breast; Copper; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Hydrogen Peroxide; Lisinopril; Penicillamine; Tumor Cells, Cultured

1999
A modified cyanide-nitroprusside method for quantifying urinary cystine concentration that corrects for creatinine interference.
    Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 289, Issue:1-2

    Topics: Adult; Artifacts; Ascorbic Acid; Captopril; Chlorides; Colorimetry; Creatinine; Cyanides; Cysteine; Cystinuria; Dose-Response Relationship, Drug; Female; Ferrous Compounds; Humans; Male; Middle Aged; Nitroprusside; Penicillamine; Reference Values; Reproducibility of Results; Serum Albumin; Tiopronin; Zinc Compounds

1999
Nitric oxide modulates captopril-mediated angiotensin-converting enzyme inhibition in porcine iliac arteries.
    European journal of pharmacology, 1999, Nov-26, Volume: 385, Issue:1

    Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Peptidyl-Dipeptidase A; S-Nitroso-N-Acetylpenicillamine; Swine; Vasoconstriction; Vasodilation

1999
Nitric oxide regulates renal cortical cyclooxygenase-2 expression.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Citrulline; Cyclooxygenase 2; Dibutyryl Cyclic GMP; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Indazoles; Isoenzymes; Kidney Cortex; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Chloride, Dietary; Thiourea

2000
Nitric oxide donors and angiotensin-converting enzyme inhibitors act in concert to inhibit human angiotensin-converting enzyme activity and platelet aggregation in vitro.
    European journal of pharmacology, 2000, Oct-06, Volume: 406, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enalaprilat; Endothelium, Vascular; Female; Humans; Molsidomine; Nitric Oxide Donors; Penicillamine; Peptidyl-Dipeptidase A; Platelet Aggregation; S-Nitroso-N-Acetylpenicillamine; Umbilical Veins

2000
Solid phase assay of urine cystine supersaturation in the presence of cystine binding drugs.
    The Journal of urology, 2001, Volume: 166, Issue:2

    Topics: Buffers; Captopril; Chemical Phenomena; Chemistry; Crystallization; Cystinuria; Humans; Penicillamine; Tiopronin

2001
Effects of S-nitroso-N-acetyl-penicillamine administration on glucose tolerance and plasma levels of insulin and glucagon in the dog.
    Nitric oxide : biology and chemistry, 2001, Volume: 5, Issue:4

    Topics: Animals; Captopril; Dogs; Female; Glucagon; Glucose; Glucose Tolerance Test; Hemodynamics; Insulin; Insulin Secretion; Male; Nitrates; Nitric Oxide Donors; Nitrites; Penicillamine

2001
Incubation of porcine iris-ciliary bodies to study the mechanisms by which nitric oxide donors lower intraocular pressure.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1

    Topics: Animals; Captopril; Ciliary Body; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intraocular Pressure; Iris; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitro Compounds; Nitrogen Oxides; Oxadiazoles; Penicillamine; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Rabbits; S-Nitrosothiols; Spermine; Swine; Time Factors

2003
Dynamics of interaction of vitamin C with some potent nitrovasodilators, S-nitroso-N-acetyl-d,l-penicillamine (SNAP) and S-nitrosocaptopril (SNOCap), in aqueous solution.
    Biophysical chemistry, 2004, Feb-01, Volume: 107, Issue:2

    Topics: Ascorbic Acid; Captopril; Catalysis; Copper; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Nitric Oxide; Osmolar Concentration; Penicillamine; S-Nitrosothiols; Sodium Chloride; Solutions; Vasodilator Agents

2004
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
    The American journal of pathology, 2004, Volume: 165, Issue:1

    Topics: Acetophenones; Acetylcholine; Alkaloids; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Benzophenanthridines; Captopril; Enzyme Inhibitors; Hypertension; Male; Models, Biological; NADPH Oxidases; Nitric Oxide Donors; Nitric Oxide Synthase; Onium Compounds; Organ Culture Techniques; Oxidative Stress; Penicillamine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Renin-Angiotensin System; Staurosporine; Superoxide Dismutase; Vasoconstrictor Agents; Vasodilator Agents

2004
Effect of cystine-binding thiol drugs on urinary cystine capacity in patients with cystinuria.
    Journal of endourology, 2005, Volume: 19, Issue:3

    Topics: Administration, Oral; Adult; Captopril; Case-Control Studies; Cysteine; Cystinuria; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Probability; Prospective Studies; Reference Values; Risk Assessment; Tiopronin; Treatment Outcome; Urinalysis

2005
[Nitric oxide/heme oxygenase-1 mediates the antioxidant effect of ACEI in rat aortic rings].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2007, Volume: 36, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Aorta, Thoracic; Bilirubin; Captopril; Heme Oxygenase-1; Hemin; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillamine; Protoporphyrins; Rats; Rats, Sprague-Dawley; Vasoconstriction

2007
Automated tagging of pharmaceutically active thiols under flow conditions using monobromobimane.
    Journal of pharmaceutical and biomedical analysis, 2011, Mar-25, Volume: 54, Issue:4

    Topics: Acetylcysteine; Analytic Sample Preparation Methods; Automation, Laboratory; Bridged Bicyclo Compounds; Captopril; Drug Stability; Fluorescent Dyes; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Limit of Detection; Penicillamine; Quality Control; Reproducibility of Results; Spectrometry, Fluorescence; Sulfhydryl Compounds; Sulfhydryl Reagents; Technology, Pharmaceutical

2011