Page last updated: 2024-08-23

captopril and morphine

captopril has been researched along with morphine in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (32.43)	18.7374
1990's	9 (24.32)	18.2507
2000's	11 (29.73)	29.6817
2010's	4 (10.81)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Jolivette, LJ; Ward, KW	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ercan, ZS; Ilhan, M; Türker, RK	2
Arora, S; Chugh, A; Gupta, YK; Seth, SD	1
Jaffe, JH; Sharpe, LG	1
Wahl, M	1
Filatov, AV	1
Hájek, I; Syková, E; Teisinger, J	1
Atkinson, J; Lal, J	1
Ilhan, M; Oktay, S; Onur, R; Türker, RK	1
Chatterjee, TK; Das, S; Ghosh, JJ	1
Bryant, HU; Kuta, CC; Yim, GK; Zabik, JE	1
Buckley, JP; Hamed, AT; Jandhyala, BS; Lokhandwala, MF	1
Harty, GJ; Yaksh, TL	1
Kishioka, S; Masuda, Y; Miyamoto, Y; Ozaki, M; Yamamoto, H	1
Calixto, JB; Corrêa, CR	1
Igarashi, H; Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Tanihara, H	1
Harris, RL; McCabe, J; Sacchetti, A; Torres, M	1
Carter, WA; Gallagher, EJ; Hamilton, RJ	1
Hiranuma, T; Iwao, K; Kitamura, K; Matsumiya, T; Oka, T	1
Cocquerelle, C; Laurent, V; Pryor, SC; Rialas, CM; Salzet, M; Salzet-Raveillon, B; Stefano, GB; Verger-Bocquet, M	1
McDermott, P; Moakes, ME; Moyer, V; Ramoska, E; Sacchetti, A	1
Alaei, H; Hosseini, M; Karimooy, HA; Shafei, MN; Sharifi, MR	1
Alaei, HA; Eslamizadeh, MJ; Headari, R; Hosseini, M	1
Alaei, HA; Gholamnezhad, Z; Havakhah, S; Hosseini, M; Neemati Karimooy, HA	1
Avci, O; Taskiran, AS	1
Bhat, R; Chari, G; Navale, S; Vidyasagar, D; Zagariya, A	1
Fluharty, S; Liu, XT; Rosenfeld, CR; Vidyasagar, D; Willis, BC; Zagariya, AM	1

Reviews

1 review(s) available for captopril and morphine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for captopril and morphine

Article	Year
Rapid improvement of acute pulmonary edema with sublingual captopril. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1996, Volume: 3, Issue:3 Topics: Acute Disease; Administration, Sublingual; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Double-Blind Method; Drug Therapy, Combination; Emergency Service, Hospital; Female; Furosemide; Humans; Male; Middle Aged; Morphine; Narcotics; Nitrates; Prospective Studies; Pulmonary Edema; Treatment Outcome	1996

Article

Year

Rapid improvement of acute pulmonary edema with sublingual captopril.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1996, Volume: 3, Issue:3

Topics: Acute Disease; Administration, Sublingual; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Double-Blind Method; Drug Therapy, Combination; Emergency Service, Hospital; Female; Furosemide; Humans; Male; Middle Aged; Morphine; Narcotics; Nitrates; Prospective Studies; Pulmonary Edema; Treatment Outcome

1996

Other Studies

35 other study(ies) available for captopril and morphine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Potentiation by angiotensin converting enzyme inhibitor, SQ, 14225, of the analgesic effect of morphine in mice. European journal of pharmacology, 1979, Sep-01, Volume: 58, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Synergism; Female; Male; Mice; Morphine; Proline; Reaction Time; Time Factors	1979
Modulation of morphine induced antinociception by intracerebroventricularly administered captopril. Indian journal of experimental biology, 1991, Volume: 29, Issue:6 Topics: Analgesics; Animals; Captopril; Drug Interactions; Injections, Intraventricular; Male; Morphine; Rats	1991
Captopril and capsaicin modify opioid withdrawal in the morphine-dependent rat. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4 Topics: Animals; Capsaicin; Captopril; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance P; Substance Withdrawal Syndrome	1989
The effect of peptides on cerebrovascular resistance in cats. Advances in experimental medicine and biology, 1985, Volume: 191 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cats; Cerebral Arteries; Enkephalins; Morphine; Naloxone; Neurotensin; Peptides; Receptors, Bradykinin; Receptors, Neurotransmitter; Receptors, Opioid; Vascular Resistance	1985
[Participation of peptide mechanisms in physiological reactions of the cardiovascular system to hyperoxia]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1985, Volume: 71, Issue:1 Topics: Animals; Captopril; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Enzyme Activation; Hemodynamics; Hemorrhage; Hyperbaric Oxygenation; Hypertension, Renovascular; Hypotension; Morphine; Oxygen; Peptides; Peptidyl-Dipeptidase A; Rats; Receptors, Opioid	1985
The effect of opioids and of naloxone on Na+,K+-adenosine triphosphatase activity in frog spinal cord membrane fractions. Neuroscience letters, 1985, Sep-06, Volume: 59, Issue:3 Topics: Animals; Captopril; Cell Membrane; Endorphins; Enkephalins; Glycopeptides; Morphine; Naloxone; Rana temporaria; Sodium-Potassium-Exchanging ATPase; Spinal Cord	1985
Involvement of the renin-angiotensin system in the dipsogenic effect of morphine. Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 278, Issue:2 Topics: Animals; Captopril; Drinking; Kidney; Male; Morphine; Nephrectomy; Rats; Rats, Inbred Strains; Renal Circulation; Renin; Renin-Angiotensin System; Saralasin	1985
Alterations by captopril of pain reactions due to thermal stimulation of the mouse foot: interactions with morphine, naloxone and aprotinin. European journal of pharmacology, 1980, May-02, Volume: 63, Issue:2-3 Topics: Animals; Aprotinin; Behavior, Animal; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enkephalins; Female; Hot Temperature; Kinins; Male; Mice; Morphine; Naloxone; Nociceptors; Proline; Prostaglandins; Reaction Time; Time Factors	1980
Potentiation of the morphine-induced respiratory rate depression by captopril. European journal of pharmacology, 1981, Mar-26, Volume: 70, Issue:3 Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Synergism; Enkephalins; Female; Male; Mice; Morphine; Proline; Respiration	1981
Adrenal involvement in captopril-induced potentiation of morphine analgesia. European journal of pharmacology, 1982, Nov-19, Volume: 85, Issue:2 Topics: Adrenal Glands; Analgesia; Angiotensin II; Animals; Captopril; Drug Synergism; Male; Mineralocorticoids; Morphine; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains	1982
Stress, endogenous opioids and salt intake. Appetite, 1984, Volume: 5, Issue:1 Topics: Angiotensin II; Animals; Captopril; Drinking; Endorphins; Food Deprivation; Injections, Intraventricular; Male; Mice; Morphine; Naloxone; Saline Solution, Hypertonic; Sodium Chloride; Stress, Physiological	1984
Relationship between plasma renin activity and hypotensive effect of captopril in dogs. Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:2 Topics: Anesthetics; Animals; Blood Pressure; Captopril; Chloralose; Depression, Chemical; Dogs; Heart Rate; Morphine; Pentobarbital; Proline; Renin; Time Factors	1980
Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5] enkephalin. European journal of pharmacology, 1982, Apr-23, Volume: 79, Issue:3-4 Topics: Amino Acids, Sulfur; Analgesics; Animals; Captopril; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Injections, Spinal; Macaca; Morphine; Neprilysin; Protease Inhibitors; Rats; Species Specificity; Thiorphan; Tiopronin	1982
Effect of some peptidase inhibitors on exogenous and endogenous opioid actions in guinea-pig ileum. Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1 Topics: Aminopeptidases; Animals; Bacitracin; Captopril; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; Leucine; Male; Morphine; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Thiorphan	1994
Evidence for participation of B1 and B2 kinin receptors in formalin-induced nociceptive response in the mouse. British journal of pharmacology, 1993, Volume: 110, Issue:1 Topics: Animals; Binding, Competitive; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Edema; Formaldehyde; Male; Mice; Morphine; Nociceptors; Pain Measurement; Receptors, Bradykinin	1993
Antitussive effect of captopril, an angiotensin converting enzyme inhibitor, in the rat. Research communications in chemical pathology and pharmacology, 1993, Volume: 81, Issue:3 Topics: Animals; Antitussive Agents; Capsaicin; Captopril; Cough; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Sprague-Dawley	1993
ED management of acute congestive heart failure in renal dialysis patients. The American journal of emergency medicine, 1993, Volume: 11, Issue:6 Topics: Acute Disease; Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Captopril; Clinical Protocols; Clonidine; Emergency Medical Services; Emergency Medicine; Heart Failure; Humans; Infusions, Intravenous; Intubation, Intratracheal; Kidney Failure, Chronic; Morphine; Nifedipine; Nitroglycerin; Nitroprusside; Oxygen Inhalation Therapy; Peritoneal Dialysis; Prospective Studies; Renal Dialysis; Severity of Illness Index; Transportation of Patients	1993
Almost complete protection from [Met5]-enkephalin-Arg6-Gly7-Leu8 (Met-enk-RGL) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2 Topics: Animals; Anti-Bacterial Agents; Captopril; Corpus Striatum; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Kinetics; Male; Morphine; Peptides; Protease Inhibitors	1997
Leech immunocytes contain proopiomelanocortin: nitric oxide mediates hemolymph proopiomelanocortin processing. Journal of immunology (Baltimore, Md. : 1950), 1997, Dec-01, Volume: 159, Issue:11 Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Arachidonic Acids; Captopril; Endocannabinoids; Hemolymph; Humans; Leeches; Molecular Sequence Data; Morphine; Nitric Oxide; Polyunsaturated Alkamides; Pro-Opiomelanocortin; Sequence Homology, Amino Acid	1997
Effect of ED management on ICU use in acute pulmonary edema. The American journal of emergency medicine, 1999, Volume: 17, Issue:6 Topics: Acute Disease; Aged; Analgesics, Opioid; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Emergency Treatment; Heart Failure; Humans; Intensive Care Units; Logistic Models; Morphine; New Jersey; Nitroglycerin; Odds Ratio; Pulmonary Edema; Respiratory Therapy; Retrospective Studies; Vasodilator Agents	1999
Effects of angiotensin II and captopril on rewarding properties of morphine. Indian journal of experimental biology, 2007, Volume: 45, Issue:9 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Conditioning, Psychological; Male; Morphine; Rats; Rats, Wistar; Renin-Angiotensin System; Reward; Self Administration	2007
Effects of microinjection of angiotensin II and captopril into nucleus accumbens on morphine self-administration in rats. Indian journal of experimental biology, 2009, Volume: 47, Issue:5 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Male; Microinjections; Morphine; Nucleus Accumbens; Rats; Rats, Wistar; Self Administration	2009
Effects of microinjection of angiotensin II and captopril to VTA on morphine self-administration in rats. Acta biologica Hungarica, 2009, Volume: 60, Issue:3 Topics: Analgesics, Opioid; Angiotensin II; Animals; Behavior, Animal; Captopril; Injections; Male; Morphine; Rats; Rats, Wistar; Reward; Self Administration; Ventral Tegmental Area	2009
Effect of captopril, an angiotensin-converting enzyme inhibitor, on morphine analgesia and tolerance in rats, and elucidating the inflammation and endoplasmic reticulum stress pathway in this effect. Neuroscience letters, 2021, 01-10, Volume: 741 Topics: Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Tolerance; Endoplasmic Reticulum Stress; Ganglia, Spinal; Inflammation; Inflammation Mediators; Male; Morphine; Nociception; Rats, Wistar	2021
Inhibition of meconium-induced cytokine expression and cell apoptosis by pretreatment with captopril. Pediatrics, 2006, Volume: 117, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Captopril; Caspase 3; Caspases; Cell Line; Cells, Cultured; Cytokines; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; Inflammation Mediators; Lung; Meconium; Rabbits; Reverse Transcriptase Polymerase Chain Reaction	2006
Meconium increases type 1 angiotensin II receptor expression and alveolar cell death. Pediatric research, 2008, Volume: 63, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Captopril; Cell Death; Cells, Cultured; Disease Models, Animal; Humans; Immunohistochemistry; Infant, Newborn; Losartan; Male; Meconium; Meconium Aspiration Syndrome; Pulmonary Alveoli; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Up-Regulation	2008