Page last updated: 2024-08-23

captopril and metoprolol

captopril has been researched along with metoprolol in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (15.94)	18.7374
1990's	27 (39.13)	18.2507
2000's	17 (24.64)	29.6817
2010's	14 (20.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y	1
Jolivette, LJ; Ward, KW	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Ma, C; Qin, S	1
Beck-Nielsen, H; Faergeman, O; Gall, MA; Gerdes, LU; Hommel, E; Lauritzen, M; Mathiesen, ER; Rossing, P; Skøtt, P; Vølund, A	1
Janssen, BJ; Struyker-Boudier, HA; Tyssen, CM	1
Abrignani, MG; Corda, M; Cosentino, F; Liquori, M; Novo, S; Pinto, A; Strano, A	1
Lithell, HO	1
Christensen, KL	1
Angioni, L; Botta, G; Capra, A; Leonetti, G; Mazzola, C; Pasotti, C; Vaccarella, A; Zanchetti, A	2
Foss, OP; Jensen, EK	1
Christensen, KL; Jespersen, LT; Mulvany, MJ	1
Bunemann, L; Jensen, K; Riisager, S; Thomsen, LJ	1
Kornerup, HJ; Korsager, S	1
Hommel, E; Mathiesen, ER; Parving, HH	1
Jha, RJ; Navani, SR; Oke, VG; Patel, K; Raghu, CN; Vatsraj, DJ; Vora, LS; Yajnik, VH	1
Bános, C; Csabuda, M; Radó, JP	1
Vidt, DG	1
Ciccone, CD; Zambraski, EJ	1
Thind, GS	1
Bucca, V; Caracausi, R; Di Pasquale, P; Licata, G; Parrinello, G; Paterna, S; Pipitone, F	1
Bucca, V; Di Pasquale, P; Licata, G; Paterna, S	1
Bucca, V; Di Pasquale, P; Magatti, M; Maringhini, G; Paterna, S	1
Carlyle, PF; Cohn, JN; Francis, GS; McDonald, KM; Rector, T	1
Spence, JD	1
Inoue, M; Kanda, T; Murata, K; Suzuki, T	1
Janssen, BJ; Oosting, J; Struyker-Boudier, HA; Tyssen, CM	1
McMullan, MR; Moore, CK; O'Connell, JB	1
Beck-Nielsen, H; Faergeman, O; Gall, MA; Gerdes, LU; Hommel, EE; Lauritzen, M; Mathiesen, ER; Rossing, P; Skøtt, P; Vølund, A	1
Becker, A; Böhler, J; Keller, E; Reetze-Bonorden, P; Schollmeyer, P; Woitas, R	1
Lacourcière, Y; Nadeau, A; Poirier, L; Tancrède, G	1
Dahlström, U; Jansson, K; Karlberg, KE; Karlsson, E; Nylander, E; Nyquist, O	2
Bhatt, AD; Dadkar, VN; Kapadia, NM; Karnik, ND; Khokhani, RC; Trivedi, TH; Vaidya, AB	1
Mandal, TK	1
Bottero, G; Ceci, V; Coletta, C; Mazzuca, V; Pasquale, M; Putini, RL; Ricci, R; Rulli, F; Salustri, A; Seccareccia, F	1
Klein, G	1
Dahlström, U; Jansson, K; Karlberg, BE; Karlberg, KE; Karlsson, E; Nylander, E; Nyquist, O	1
Dahlström, U; Hagerman, I; Jansson, K; Karlberg, KE; Nylander, E; Nyquist, O; Ostlund, R	1
Di Pasquale, P; Paterna, S	1
Isaksson, H; Kahan, T; Malmqvist, K; Ostergren, J	1
Bottero, G; Ceci, V; Coletta, C; Pajes, G; Pasquale, M; Putini, RL; Ricci, R; Salustri, A	1
He, H; Xu, Y; Zhao, W	1
Wang, H; Yuan, L	1
Cohen-Solal, A; Dietz, R; Eichhorn, E; Erhardt, L; Hobbs, FD; Krum, H; Maggioni, A; McKelvie, RS; McMurray, J; Piña, IL; Soler-Soler, J; Swedberg, K	1
Abel, ED; Bisping, E; Buerger, A; Dorfman, AL; Izumo, S; Jay, PY; Pu, WT; Rozhitskaya, O; Sherwood, MC	1
Arsenault, M; Beaudoin, J; Bojmehrani, A; Champetier, S; Couet, J; Lachance, D; Plante, E; Roussel, E	1
Bolen, MA; Halliburton, SS; Schoenhagen, P	1
Blaich, A; Domes, K; Hofmann, F; Lenhardt, P; Lipp, P; Moosmang, S; Oberhofer, M; Pahlavan, S; Poomvanicha, M; Ruppenthal, S; Scholz, A; Tian, Q; Wegener, JW	1
Figtree, GA; Fry, NA; Galougahi, KK; Garcia, A; Hamilton, EJ; Liu, CC; Rasmussen, HH	1
Ding, Z; Ge, J; Gong, H; Jiang, G; Li, Y; Wang, S; Wang, X; Wu, J; Ye, Y; Yin, P; Yuan, J; Zhang, W; Zhou, J; Zou, Y	1
Blain, A; Blamire, AM; Greally, E; Laval, SH; MacGowan, GA; Straub, VW	1
Akalın, F; Erolu, E; Saylan Çevik, B; Yücelten, D	1

Reviews

3 review(s) available for captopril and metoprolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism. Diabetes care, 1991, Volume: 14, Issue:3 Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Lipid Metabolism; Meta-Analysis as Topic; Metoprolol; Pindolol; Propranolol; Prospective Studies	1991
Advances in the medical management of renovascular hypertension. The Urologic clinics of North America, 1984, Volume: 11, Issue:3 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Atenolol; Captopril; Dipeptides; Enalapril; Female; Humans; Hypertension, Renovascular; Male; Metoprolol; Middle Aged; Nadolol; Pindolol; Propanolamines; Propranolol; Renal Artery Obstruction; Renin-Angiotensin System; Saralasin; Timolol	1984

Trials

23 trial(s) available for captopril and metoprolol

Article	Year
Placebo-controlled comparison of captopril, metoprolol, and hydrochlorothiazide therapy in non-insulin-dependent diabetic patients with primary hypertension. American journal of hypertension, 1992, Volume: 5, Issue:5 Pt 1 Topics: Aged; Captopril; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Hypoglycemic Agents; Lipids; Male; Metoprolol; Middle Aged	1992
Regression of structural vascular changes after chronic treatment in hypertensives. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6 Topics: Acebutolol; Adult; Aged; Blood Pressure; Captopril; Female; Hemodynamics; Humans; Hypertension; Labetalol; Leg; Male; Metoprolol; Middle Aged; Regional Blood Flow; Vascular Resistance	1991
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism. Diabetes care, 1991, Volume: 14, Issue:3 Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Lipid Metabolism; Meta-Analysis as Topic; Metoprolol; Pindolol; Propranolol; Prospective Studies	1991
Treatment of hypertension in the elderly: effects on blood pressure, heart rate, and physical fitness. The American journal of medicine, 1991, Volume: 90, Issue:3A Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Captopril; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Physical Endurance; Physical Fitness	1991
The effect of captopril and metoprolol as monotherapy or combined with bendroflumethiazide on blood lipids. Journal of internal medicine, 1990, Volume: 227, Issue:2 Topics: Adult; Aged; Bendroflumethiazide; Body Weight; Captopril; Cholesterol; Cholesterol, HDL; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Lipids; Male; Metoprolol; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Triglycerides	1990
Cerebral blood flow during anaesthesia: influence of pretreatment with metoprolol or captopril. British journal of anaesthesia, 1989, Volume: 62, Issue:3 Topics: Adult; Anesthesia, General; Blood Pressure; Captopril; Cerebrovascular Circulation; Female; Humans; Male; Metoprolol; Middle Aged; Preanesthetic Medication	1989
[The effects of captopril and metoprolol on blood pressure and side effects in patients with mild to moderate hypertension]. Ugeskrift for laeger, 1989, Apr-03, Volume: 151, Issue:14 Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Random Allocation	1989
Antihypertensive efficacy and influence on physical activity of three different treatments in elderly hypertensive patients. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6 Topics: Aged; Amiloride; Antihypertensive Agents; Captopril; Drug Evaluation; Drug Therapy, Combination; Drug Tolerance; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Physical Endurance	1989
Comparative evaluation of captopril and metoprolol as first choice anti-hypertensive in Indian patients. The British journal of clinical practice, 1988, Volume: 42, Issue:10 Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Middle Aged; Random Allocation	1988
Effects of captopril on plasma endothelin-1 during thrombolysis: preliminary findings. Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:2 Topics: Administration, Oral; Adult; Aged; Blood Pressure; Captopril; Double-Blind Method; Drug Therapy, Combination; Endothelins; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Recombinant Proteins; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator	1995
Effects of administration of captopril, metoprolol, and the captopril-metoprolol combination as adjuvant therapy during thrombolysis in acute myocardial infarction. Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:6 Topics: Captopril; Drug Combinations; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Single-Blind Method; Thrombolytic Therapy	1994
Effects of the administration of captopril, metoprolol and of the captopril-metoprolol combination as adjuvant therapy during thrombolysis in acute myocardial infarction. International journal of cardiology, 1994, Volume: 46, Issue:2 Topics: Aged; Captopril; Chemotherapy, Adjuvant; Creatine Kinase; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Stroke Volume; Survival Rate; Tachycardia, Ventricular; Thrombolytic Therapy; Time Factors	1994
Effects of antihypertensive drugs on flow disturbances: nifedipine, captopril, and metoprolol evaluated by quantitative spectral analysis of Doppler flow patterns in patients with carotid stenosis. Clinical and investigative medicine. Medecine clinique et experimentale, 1994, Volume: 17, Issue:4 Topics: Aged; Blood Pressure; Captopril; Cardiac Output; Carotid Stenosis; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Laser-Doppler Flowmetry; Male; Metoprolol; Nifedipine; Regional Blood Flow; Vascular Resistance	1994
[The effect of captopril, metoprolol and hydrochlorothiazide therapy in patients with non-insulin-dependent diabetes (NIDDM) and primary hypertension. A double-blind, randomized cross-over study]. Ugeskrift for laeger, 1993, Mar-01, Volume: 155, Issue:9 Topics: Aged; Captopril; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged	1993
Captopril or conventional therapy in hypertensive type II diabetics. Three-year analysis. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:6 Pt 1 Topics: Aged; Albuminuria; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Metoprolol; Middle Aged; Prospective Studies	1993
More favourable haemodynamic effects from metoprolol than from captopril in patients with dilated cardiomyopathy. European heart journal, 1997, Volume: 18, Issue:7 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiac Output; Cardiomyopathy, Dilated; Double-Blind Method; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Prospective Studies; Stroke Volume; Ventricular Pressure	1997
Nifedipine, captopril, metoprolol and nifedipine with metoprolol in hypertensive crisis in non-intensive care setting. The Journal of the Association of Physicians of India, 1996, Volume: 44, Issue:7 Topics: Acute Disease; Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Captopril; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Safety; Treatment Outcome; Vasodilator Agents	1996
Effects of early treatment with captopril and metoprolol singly or together on six-month mortality and morbidity after acute myocardial infarction. Results of the RIMA (Rimodellamento Infarto Miocardico Acuto) study. The RIMA researchers. Giornale italiano di cardiologia, 1999, Volume: 29, Issue:2 Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Disease-Free Survival; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Prospective Studies; Time Factors; Treatment Outcome	1999
Combination therapy with felodipine and metoprolol compared with captopril and hydrochlorothiazide. German MC Study Group. Blood pressure, 1998, Volume: 7, Issue:5-6 Topics: Antihypertensive Agents; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged	1998
The effects of metoprolol and captopril on heart rate variability in patients with idiopathic dilated cardiomyopathy. Clinical cardiology, 1999, Volume: 22, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopathy, Dilated; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged	1999
The value of repeated echocardiographic evaluation in patients with idiopathic dilated cardiomyopathy during treatment with metoprolol or captopril. Scandinavian cardiovascular journal : SCJ, 2000, Volume: 34, Issue:3 Topics: Adult; Captopril; Cardiomyopathy, Dilated; Double-Blind Method; Echocardiography, Doppler; Female; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Prospective Studies; Reproducibility of Results; Treatment Outcome; Ventricular Function, Left	2000
Regression of left ventricular mass with captopril and metoprolol, and the effects on glucose and lipid metabolism. Blood pressure, 2001, Volume: 10, Issue:2 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Echocardiography; Female; Humans; Hypertrophy, Left Ventricular; Insulin; Insulin Resistance; Lipids; Male; Metoprolol; Middle Aged	2001
Effect of early treatment with captopril and metoprolol singly and together on postinfarction left ventricular remodeling. American heart journal, 2001, Volume: 142, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Combination; Echocardiography; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Prospective Studies; Treatment Outcome; Ventricular Remodeling	2001

Other Studies

44 other study(ies) available for captopril and metoprolol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Interaction of digoxin with antihypertensive drugs via MDR1. Life sciences, 2002, Feb-15, Volume: 70, Issue:13 Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors	2002
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Changes in lymphocyte beta-receptor density in patients with heart failure before and after metoprolol or captopril administration]. Zhonghua xin xue guan bing za zhi, 1992, Volume: 20, Issue:3 Topics: Adult; Aged; Captopril; Cardiomyopathy, Dilated; Female; Heart Failure; Humans; Lymphocytes; Male; Metoprolol; Middle Aged; Receptors, Adrenergic, beta; Rheumatic Heart Disease; Stroke Volume; Ventricular Function	1992
Modification of circadian blood pressure and heart rate variability by five different antihypertensive agents in spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Heart Rate; Hydralazine; Hypertension; Male; Metoprolol; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1991
Reducing pulse pressure in hypertension may normalize small artery structure. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:6 Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Captopril; Dihydropyridines; Heart Rate; Hydralazine; Hypertension; Indoles; Isradipine; Male; Metoprolol; Perindopril; Pulse; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regression Analysis	1991
Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure. Journal of hypertension, 1989, Volume: 7, Issue:2 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hydralazine; Hypertension; Indoles; Isradipine; Male; Mesenteric Arteries; Mesenteric Veins; Metoprolol; Perindopril; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance	1989
[Multicenter clinical trial on the prevention of sudden death after myocardial infarction by the use of anti-arrhythmia agents. Investigator Group of the Spanish Study on Sudden Death]. Revista espanola de cardiologia, 1989, Volume: 42, Issue:2 Topics: Amiodarone; Arrhythmias, Cardiac; Captopril; Death, Sudden; Humans; Metoprolol; Multicenter Studies as Topic; Myocardial Infarction; Spain	1989
Converting enzyme-inhibition in diabetic nephropathy. Contributions to nephrology, 1989, Volume: 73 Topics: Albuminuria; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Therapy, Combination; Furosemide; Glomerular Filtration Rate; Humans; Hydralazine; Hypertension; Metoprolol; Prospective Studies	1989
Influence of body posture on aldosterone suppression after antihypertensive drugs (captopril and metoprolol). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:11 Topics: Aldosterone; Captopril; Humans; Metoprolol; Posture	1985
Effects of phenoxybenzamine, metoprolol, captopril, and meclofenamate on cardiovascular function in deoxycorticosterone acetate hypertensive Yucatan miniature swine. Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:2 Topics: Animals; Blood Pressure; Captopril; Desoxycorticosterone; Female; Heart Rate; Hemodynamics; Hypertension; Male; Meclofenamic Acid; Metoprolol; ortho-Aminobenzoates; Phenoxybenzamine; Proline; Propanolamines; Swine; Swine, Miniature	1983
Newer antihypertensive agents. Comprehensive therapy, 1980, Volume: 6, Issue:3 Topics: Aged; Antihypertensive Agents; Captopril; Diuretics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Mineralocorticoid Receptor Antagonists; Pindolol; Saralasin; Timolol; United States; Vasoconstrictor Agents	1980
Angiotensin-converting enzyme inhibition and beta-adrenoceptor blockade regress established ventricular remodeling in a canine model of discrete myocardial damage. Journal of the American College of Cardiology, 1994, Volume: 24, Issue:7 Topics: Animals; Captopril; Dogs; Hemodynamics; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Metoprolol; Myocardial Infarction; Random Allocation; Stroke Volume; Ventricular Function	1994
Low-dose combination therapy with metoprolol and captopril for congestive heart failure in mice. Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:5 Topics: Animals; Captopril; Drug Therapy, Combination; Female; Heart Failure; Heart Ventricles; Metoprolol; Mice; Mice, Inbred C3H; Myocardium; Necrosis; Organ Size	1993
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats. Chronobiology international, 1993, Volume: 10, Issue:6 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes	1993
Diagnosis and management of peripartum cardiomyopathy. Hospital practice (Office ed.), 1993, Nov-15, Volume: 28, Issue:11 Topics: Adult; Algorithms; Captopril; Cardiomyopathies; Diagnosis, Differential; Digoxin; Drug Administration Schedule; Female; Furosemide; Humans; Metoprolol; Postpartum Period; Prognosis	1993
Effect of antihypertensive drugs on glomerular hyperfiltration and renal haemodynamics. Comparison of captopril with nifedipine, metoprolol and celiprolol. European journal of clinical pharmacology, 1993, Volume: 44 Suppl 1 Topics: Antihypertensive Agents; Captopril; Celiprolol; Dietary Proteins; Glomerular Filtration Rate; Humans; Insulin; Metoprolol; Nifedipine; p-Aminohippuric Acid; Renal Circulation; Stimulation, Chemical	1993
Evaluation of a novel phase separation technique for the encapsulation of water-soluble drugs in biodegradable polymer. Drug development and industrial pharmacy, 1998, Volume: 24, Issue:7 Topics: Adrenergic beta-Antagonists; Antifungal Agents; Antihypertensive Agents; Biodegradation, Environmental; Calcium Channel Blockers; Captopril; Diltiazem; Drug Compounding; Drug Delivery Systems; Evaluation Studies as Topic; Lactic Acid; Metoprolol; Pentamidine; Polyesters; Polyglycolic Acid; Polymers; Solubility; Water	1998
The circulating renin-angiotensin system during treatment with metoprolol or captopril in patients with heart failure due to non-ischaemic dilated cardiomyopathy. Journal of internal medicine, 1999, Volume: 245, Issue:5 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Cardiomyopathy, Dilated; Exercise; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Renin; Rest	1999
[The effect of a combination ACE inhibitor and beta-blockers in acute myocardial infarct]. Giornale italiano di cardiologia, 1999, Volume: 29, Issue:8 Topics: Acute Disease; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Combinations; Humans; Metoprolol; Myocardial Infarction	1999
[Clinical study on treatment of mild-middle degree congestive heart failure with integrated traditional Chinese and Western medicine]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2000, Volume: 20, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Aged; Captopril; Coronary Disease; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged	2000
TCM treatment of hypertrophic cardiomyopaphy--a case report. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2002, Volume: 22, Issue:3 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopathy, Hypertrophic; Female; Humans; Male; Metoprolol; Middle Aged	2002
Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice. European journal of heart failure, 2005, Volume: 7, Issue:5 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzopyrans; Biphenyl Compounds; Bisoprolol; Captopril; Carbazoles; Carvedilol; Drug Therapy, Combination; Enalapril; Ethanolamines; Evidence-Based Medicine; Guideline Adherence; Heart Failure; Humans; Indoles; Lisinopril; Metoprolol; Mineralocorticoid Receptor Antagonists; Nebivolol; Practice Guidelines as Topic; Propanolamines; Ramipril; Spironolactone; Stroke Volume; Tetrazoles; Valine; Valsartan	2005
Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase. Journal of cardiac failure, 2006, Volume: 12, Issue:5 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Biomarkers; Captopril; Cardiomyopathy, Dilated; Gene Expression; Heart; Heart Failure; Integrases; Male; Metoprolol; Mice; Mice, Inbred Strains; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Organ Size; Survival Analysis; Up-Regulation	2006
Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:3 Topics: Acute Disease; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Insufficiency; Captopril; Disease Models, Animal; Extracellular Matrix Proteins; Gene Expression Profiling; Gene Expression Regulation; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Metoprolol; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Severity of Illness Index; Time Factors	2009
Iterative CT reconstruction of aortic intramural hematoma. Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:7 Topics: Amlodipine; Aortic Aneurysm; Aortic Dissection; Captopril; Drug Therapy, Combination; Female; Hematoma; Humans; Hydralazine; Metoprolol; Middle Aged; Multidetector Computed Tomography; Simvastatin; Treatment Outcome	2011
Mutation of the calmodulin binding motif IQ of the L-type Ca(v)1.2 Ca2+ channel to EQ induces dilated cardiomyopathy and death. The Journal of biological chemistry, 2012, Jun-29, Volume: 287, Issue:27 Topics: Amino Acid Motifs; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Binding Sites; Calcium; Calcium Channels, L-Type; Calmodulin; Captopril; Cardiomyopathy, Dilated; Cells, Cultured; Heart Failure; Metoprolol; Mice; Mice, Mutant Strains; Myocardial Contraction; Myocytes, Cardiac; Protein Structure, Tertiary; Survival Rate	2012
Protein kinase-dependent oxidative regulation of the cardiac Na+-K+ pump: evidence from in vivo and in vitro modulation of cell signalling. The Journal of physiology, 2013, Jun-15, Volume: 591, Issue:12 Topics: Action Potentials; Adenylyl Cyclases; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glutaredoxins; Male; Metoprolol; Myocytes, Cardiac; NADPH Oxidases; Oxidation-Reduction; Protein Kinase C; Protein Kinase Inhibitors; Protein Subunits; Rabbits; Signal Transduction; Sodium-Potassium-Exchanging ATPase	2013
Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice. Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Autophagy; Blood Pressure; Captopril; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Drugs, Chinese Herbal; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Metoprolol; Mice, Inbred C57BL; Myocytes, Cardiac; Signal Transduction; Tetrazoles; Ventricular Function, Left; Ventricular Remodeling	2015
Absence of Cardiac Benefit with Early Combination ACE Inhibitor and Beta Blocker Treatment in mdx Mice. Journal of cardiovascular translational research, 2015, Volume: 8, Issue:3 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; Cardiac Catheterization; Cardiomyopathies; Disease Models, Animal; Drug Therapy, Combination; Magnetic Resonance Imaging; Male; Metoprolol; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myocardium; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure	2015
Arrhythmogenic right ventricular dysplasia, cutaneous manifestations and desmoplakin mutation: Carvajal syndrome. Pediatrics international : official journal of the Japan Pediatric Society, 2018, Volume: 60, Issue:10 Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arrhythmogenic Right Ventricular Dysplasia; Captopril; Cardiomyopathies; Cardiomyopathy, Dilated; Child, Preschool; Defibrillators, Implantable; Desmoplakins; Diuretics; Echocardiography; Electrocardiography; Furosemide; Hair Diseases; Heart Failure; Humans; Keratoderma, Palmoplantar; Magnetic Resonance Imaging, Cine; Male; Metoprolol; Mutation	2018