Page last updated: 2024-08-23

captopril and meropenem

captopril has been researched along with meropenem in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's11 (64.71)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bai, Y; Gan, M; Gao, R; Guan, Y; He, W; Li, L; Li, Y; Liu, Y; Xiao, C; You, X; Yu, L1
Carlsen, TJ; Christopeit, T; Helland, R; Leiros, HK1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Christopeit, T; Leiros, HK1
Bai, W; Cheng, K; Gao, Y; Guo, H; He, W; Li, C; Li, Z; Wu, C1
Breeze, AL; Gao, N; Hu, J; Ma, J; MacCormack, K; McLeod, S; Sriram, S1
Arakawa, Y; Jin, W; Kimura, K; Kurosaki, H; Mori, S; Wachino, J; Yamaguchi, Y1
Albert, A; Christopeit, T; Leiros, HS1
Han, J; Hu, F; Liang, Y; Meng, Z; Sun, X; Tang, ML; Yu, JM; Yu, L; Zhang, C1
Dai, Y; Gao, Y; Li, H; Li, J; Liu, Y; Sun, K; Yue, C; Zhang, H; Zhao, D1

Reviews

1 review(s) available for captopril and meropenem

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for captopril and meropenem

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Polyketides with New Delhi metallo-β-lactamase 1 inhibitory activity from Penicillium sp.
    Journal of natural products, 2013, Sep-27, Volume: 76, Issue:9

    Topics: Alkaloids; beta-Lactamase Inhibitors; beta-Lactamases; China; Circular Dichroism; Crystallography, X-Ray; Inhibitory Concentration 50; Molecular Structure; Penicillium; Polyketides; Quinolones; Rhizosphere

2013
Discovery of Novel Inhibitor Scaffolds against the Metallo-β-lactamase VIM-2 by Surface Plasmon Resonance (SPR) Based Fragment Screening.
    Journal of medicinal chemistry, 2015, Nov-12, Volume: 58, Issue:21

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Crystallography, X-Ray; Drug Design; Drug Resistance, Bacterial; Humans; Models, Molecular; Pseudomonas aeruginosa; Pseudomonas Infections; Small Molecule Libraries; Surface Plasmon Resonance

2015
Fragment-based discovery of inhibitor scaffolds targeting the metallo-β-lactamases NDM-1 and VIM-2.
    Bioorganic & medicinal chemistry letters, 2016, Apr-15, Volume: 26, Issue:8

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Dose-Response Relationship, Drug; Drug Discovery; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Surface Plasmon Resonance

2016
A novel potent metal-binding NDM-1 inhibitor was identified by fragment virtual, SPR and NMR screening.
    Bioorganic & medicinal chemistry, 2020, 05-01, Volume: 28, Issue:9

    Topics: Anti-Bacterial Agents; beta-Lactamases; Coordination Complexes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Klebsiella pneumoniae; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Surface Plasmon Resonance; Zinc

2020
Real-time monitoring of New Delhi metallo-β-lactamase activity in living bacterial cells by 1H NMR spectroscopy.
    Angewandte Chemie (International ed. in English), 2014, Feb-17, Volume: 53, Issue:8

    Topics: Anti-Bacterial Agents; beta-Lactamases; Captopril; Drug Resistance, Bacterial; Edetic Acid; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Magnetic Resonance Spectroscopy; Meropenem; Spermine; Thienamycins

2014
Structural Insights into Recognition of Hydrolyzed Carbapenems and Inhibitors by Subclass B3 Metallo-β-Lactamase SMB-1.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; beta-Lactamases; Captopril; Carbapenems; Catalytic Domain; Crystallography, X-Ray; Doripenem; Imipenem; Meropenem; Mesna; Protein Structure, Secondary; Protein Structure, Tertiary; Serratia marcescens; Thienamycins

2016
Discovery of a novel covalent non-β-lactam inhibitor of the metallo-β-lactamase NDM-1.
    Bioorganic & medicinal chemistry, 2016, 07-01, Volume: 24, Issue:13

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Captopril; Catalytic Domain; Drug Discovery; Enzyme Activation; Kinetics; Meropenem; Models, Molecular; Mutagenesis, Site-Directed; Spectrometry, Mass, Electrospray Ionization; Surface Plasmon Resonance; Thienamycins

2016
Novel Mercapto Propionamide Derivatives with Potent New Delhi Metallo-β-Lactamase-1 Inhibitory Activity and Low Toxicity.
    ACS infectious diseases, 2019, 06-14, Volume: 5, Issue:6

    Topics: Amides; Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Captopril; Cell Line; Cell Survival; Crystallography, X-Ray; Female; Gram-Negative Bacteria; HEK293 Cells; Humans; Inhibitory Concentration 50; Meropenem; Mice; Mice, Inbred ICR

2019
Captopril potentiated meropenem activity against MBL-producing carbapenem-resistant Klebsiella pneumoniae: in vitro and in vivo study.
    Journal of inorganic biochemistry, 2021, Volume: 218

    Topics: Anti-Bacterial Agents; Antihypertensive Agents; beta-Lactamases; Captopril; Carbapenem-Resistant Enterobacteriaceae; Drug Therapy, Combination; Humans; In Vitro Techniques; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests

2021