captopril has been researched along with isradipine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jespersen, LT; Krusell, LR; Pedersen, EB; Pedersen, OL; Sihm, I; Thomsen, K | 1 |
| Fitscha, P; Hitzenberger, G; Meisner, W | 2 |
| Christensen, KL | 1 |
| Christensen, KL; Jespersen, LT; Mulvany, MJ | 1 |
| Dahlöf, B; Eggertsen, R; Hansson, L; Svensson, A | 1 |
| Amir, M; Bar-On, D; Cristal, N; Loidl, A | 1 |
| Cristal, N; Yodfat, Y | 1 |
| Hansson, L | 1 |
| Amir, M; Bar-On, D; Cristal, N; Yodfat, Y | 1 |
| Campbell, O; Guasch, A; Macon, E; Nzerue, C; Parham, M; Zayas, CF | 1 |
| de Moura, RS; Ferraz, MM; Ferraz, MR; Santos, R | 1 |
2 review(s) available for captopril and isradipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Isradipine: a profile in essential hypertension.
Topics: Animals; Captopril; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Pindolol; Quality of Life | 1993 |
7 trial(s) available for captopril and isradipine
| Article | Year |
|---|---|
Evaluation of isradipine and captopril alone or in combination for the treatment of hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Isradipine; Male; Middle Aged | 1991 |
Antihypertensive effects of isradipine and captopril as monotherapy or in combination.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Male; Middle Aged; Pyridines | 1991 |
Additive effect of isradipine in combination with captopril in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Placebos; Pyridines; Random Allocation | 1989 |
Does the combination of ACE inhibitor and calcium antagonist control hypertension and improve quality of life? The LOMIR-MCT-IL study experience.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Male; Methyldopa; Middle Aged; Quality of Life | 1994 |
A multicenter, double-blind, randomized, placebo-controlled study of isradipine and methyldopa as monotherapy or in combination with captopril in the treatment of hypertension. The LOMIR-MCT-IH Research Group.
Topics: Adult; Captopril; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Male; Methyldopa; Middle Aged; Treatment Outcome | 1993 |
Quality of life in normotensives compared to hypertensive men treated with isradipine or methyldopa as monotherapy or in combination with captopril: the LOMIR-MCT-IL study.
Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Case-Control Studies; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Isradipine; Male; Methyldopa; Middle Aged; Quality of Life; Treatment Outcome | 1996 |
Contrasting effects of calcium channel blockade versus converting enzyme inhibition on proteinuria in African Americans with non-insulin-dependent diabetes mellitus and nephropathy.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Black People; Calcium Channel Blockers; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Isradipine; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Proteinuria | 1997 |
12 other study(ies) available for captopril and isradipine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Combined actions of isradipine and captopril on renal function in hypertension.
Topics: Adult; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Isradipine; Kidney; Male; Middle Aged | 1992 |
Reducing pulse pressure in hypertension may normalize small artery structure.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Captopril; Dihydropyridines; Heart Rate; Hydralazine; Hypertension; Indoles; Isradipine; Male; Metoprolol; Perindopril; Pulse; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regression Analysis | 1991 |
Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hydralazine; Hypertension; Indoles; Isradipine; Male; Mesenteric Arteries; Mesenteric Veins; Metoprolol; Perindopril; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance | 1989 |
Preventing L-NAME inhibitory effects on rat sexual behavior with hydralazine, isradipine or captopril co-treatment.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Captopril; Drug Interactions; Ejaculation; Enzyme Inhibitors; Female; Hydralazine; Isradipine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sexual Behavior, Animal; Time Factors; Vasodilator Agents | 2003 |