captopril has been researched along with isosorbide-5-mononitrate in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Andrews, R; Cowley, AJ; Evans, A; Walsh, JT | 1 |
| Budaj, A; Cedro, K; Collins, R; Fitzgerald, L; Flather, M; Hargreaves, A; Jacob, A; Kolettis, T; Millane, T; Pipilis, A | 1 |
| Faggiano, P; Ghizzoni, G; Lombardi, C; Rusconi, C; Sorgato, A; Spedini, C | 1 |
| Mollace, V; Pistelli, A; Salvemini, D | 1 |
| Appleby, P; Coats, A; Collins, R; Conway, M; Flather, M; Pipilis, A; Sleight, P | 1 |
| Caspi, A; Ermer, W; Lewis, BS; Markiewicz, W; Rabinowitz, B; Rosenfeld, T; Schlesinger, Z; Sclarovsky, S | 1 |
| Barin, ES; Gilfillan, KL; Stokes, GS | 1 |
| Gottsäter, A; Ohlin, AK; Ohlin, H; Tingberg, E | 1 |
7 trial(s) available for captopril and isosorbide-5-mononitrate
| Article | Year |
|---|---|
Failure of "effective" treatment for heart failure to improve normal customary activity.
Topics: Activities of Daily Living; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chronic Disease; Deoxyepinephrine; Dopamine Agonists; Exercise Test; Exercise Tolerance; Female; Heart Failure; Humans; Indoles; Isosorbide Dinitrate; Male; Middle Aged; Single-Blind Method; Treatment Failure; Vasodilator Agents | 1995 |
ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative
Topics: Administration, Oral; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Delayed-Action Preparations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Magnesium Sulfate; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy; Vasodilator Agents | 1995 |
Randomized controlled trial of oral captopril, of oral isosorbide mononitrate and of intravenous magnesium sulphate started early in acute myocardial infarction: safety and haemodynamic effects. ISIS-4 (Fourth International Study of Infarct Survival) Pilo
Topics: Captopril; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Magnesium Sulfate; Male; Middle Aged; Myocardial Infarction; Patient Compliance; Pilot Projects; Research Design; Safety; Time Factors; Vasodilator Agents | 1994 |
Hemodynamic effects of captopril and isosorbide mononitrate started early in acute myocardial infarction: a randomized placebo-controlled study.
Topics: Aged; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Isosorbide; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Pilot Projects | 1993 |
Effect of isosorbide-5-mononitrate on exercise performance and clinical status in patients with congestive heart failure. Results of the Nitrates in Congestive Heart Failure (NICE) Study.
Topics: Administration, Oral; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Double-Blind Method; Electrocardiography; Exercise Test; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Quality of Life; Vasodilator Agents | 1999 |
Effects of isosorbide mononitrate and AII inhibition on pulse wave reflection in hypertension.
Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Imidazoles; Isosorbide Dinitrate; Male; Middle Aged; Pulse; Thiophenes; Time Factors; Vasodilator Agents | 2003 |
Lipid peroxidation is not increased in heart failure patients on modern pharmacological therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Comorbidity; Delayed-Action Preparations; Dinoprost; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Nitric Oxide Donors; Oxidative Stress; Ramipril; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left | 2006 |
10 other study(ies) available for captopril and isosorbide-5-mononitrate
| Article | Year |
|---|---|
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Fourth International Study of Infarct Survival: protocol for a large simple study of the effects of oral mononitrate, of oral captopril, and of intravenous magnesium. ISIS-4 collaborative group.
Topics: Administration, Oral; Captopril; Clinical Trials as Topic; Delayed-Action Preparations; Fibrinolytic Agents; Humans; Injections, Intravenous; Isosorbide Dinitrate; Magnesium; Multicenter Studies as Topic; Myocardial Infarction; Placebos; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Thrombolytic Therapy | 1991 |
Pulmonary function tests in patients with congestive heart failure: effects of medical therapy.
Topics: Adult; Aged; Captopril; Cardiovascular Agents; Digoxin; Dobutamine; Drug Therapy, Combination; Echocardiography, Doppler; Forced Expiratory Volume; Furosemide; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Nitroprusside; Vasodilator Agents; Vital Capacity | 1993 |
Release of nitric oxide from glyceryl trinitrate by captopril but not enalaprilat: in vitro and in vivo studies.
Topics: Acetylcysteine; Animals; Captopril; Cattle; Enalapril; Endothelium, Vascular; Glutathione; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Rats; Rats, Wistar; Vasodilator Agents | 1993 |