captopril has been researched along with hydrochlorothiazide in 322 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 160 (49.69) | 18.7374 |
| 1990's | 93 (28.88) | 18.2507 |
| 2000's | 35 (10.87) | 29.6817 |
| 2010's | 30 (9.32) | 24.3611 |
| 2020's | 4 (1.24) | 2.80 |
| Authors | Studies |
|---|---|
| Barton, JN; Desai, R; Goetzen, T; Golec, FS; Menard, PR; Piwinski, JJ; Regan, JR; Reilly, LW; Skiles, JW; Ueng, SN | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 1 |
| Johnston, CI; Matthews, PG; McGrath, BP | 1 |
| Andrews, CD; Bulpitt, CJ; Callaghan, TS; Fletcher, AE; Palmer, AJ; Rudge, PJ | 1 |
| Horubała-Bielak, G; Kolber-Postepska, B; Markiewicz, M; Zebrowska-Lupina, I | 1 |
| Chuster, M; Curi, PR; Ferreira Filho, SR; Franco, RJ; Kohlmann Júnior, O; Leite, JB; Lorga, AM; Mion Júnior, DM; Salomão Filho, A; Spritzer, N | 1 |
| Balbi, AL; Franco, RJ; Luna, RL; Martin, LC; Sampaio, M | 1 |
| Thurston, H | 1 |
| Dusleag, J; Klein, W; Ratheiser, K; Seitl, K; Titscher, G | 1 |
| Masenko, VP; Mazur, NA; Tomashets, EA | 1 |
| Atkinson, J; Capdeville-Atkinson, C; Chillon, JM; Guillou, J; Lartaud, I; Mertès, PM | 1 |
| Collatina, S; Ferroni, C; Salzano, E | 1 |
| Blaufox, MD; Lee, HB | 1 |
| Beck-Nielsen, H; Faergeman, O; Gall, MA; Gerdes, LU; Hommel, E; Lauritzen, M; Mathiesen, ER; Rossing, P; Skøtt, P; Vølund, A | 1 |
| Dohmoto, H; Fujiyoshi, T; Hashiguchi, Y; Hayashi, Y; Hosono, M; Iida, H; Ikeda, K; Yoshimoto, R | 1 |
| Lacourcière, Y; Lévesque, C; Poirier, L; Provencher, P | 1 |
| Rappelli, A | 1 |
| Graham, RD | 1 |
| Goldstein, RJ | 1 |
| Fraser, I; Howes, L; Kincaid-Smith, PS; Louis, W; MacDonald, G; Matthews, PG; McGrath, BP; Rallings, M; Scheinkestel, C; Whitworth, JA | 1 |
| Desche, P; Thurston, H | 1 |
| Frishman, WH; Greenberg, S | 1 |
| Clarke, PF; Hornby, R; Kendall, MJ; Kendall, R | 1 |
| Lederle, RM | 3 |
| Lacourcière, Y; Nadeau, A; Poirier, L; Tancrède, G | 2 |
| Holzgreve, H; Klüglich, M; Middeke, M | 1 |
| Guivarc'h, PH; Lacourcière, Y; Poirier, L; Provencher, P | 1 |
| Battisti, G; Calimici, R; Marrollo, E | 1 |
| Jones, DW; Sands, CD | 1 |
| Angioni, L; Botta, G; Capra, A; Leonetti, G; Mazzola, C; Pasotti, C; Vaccarella, A; Zanchetti, A | 2 |
| Höfling, B; Lorenz, HM; von Pölnitz, A | 1 |
| Di Monte, M; Tamburrini, LR | 1 |
| MacGregor, GA; Markandu, ND; Miller, MA; Singer, DR; Sugden, AL | 1 |
| Allen, DH; Beilin, LJ; Morton, AR; Puddey, IB | 1 |
| Fouad-Tarazi, FM; Kobayashi, H; Sano, T; Tarazi, RC | 1 |
| Averbukh, Z; Berman, S; Cohn, M; Golik, A; Maor, J; Modai, D; Shaked, U | 1 |
| Alcántara Nicolás, J; Cano Cano, E; Cano Cano, R; Contreras, C; García Galvis, JA; García Giralda, L; González Comeche, J; Madrid Conesa, A; Ramos La Torre, F; Sánchez Moreno, J | 1 |
| Berne, C; Lithell, H; Pollare, T | 2 |
| Ferrari, T; Finardi, G; Marchesi, E; Martignoni, A; Muggia, C; Perani, G; Pompei, R; Simonich, P | 1 |
| Baume, RM; Croog, SH; Levine, S; Schoenberger, JA; Sudilovsky, A | 1 |
| Furnival, L; Khoshnodi, L; MacGregor, GA; Markandu, ND; Singer, DR | 1 |
| Desche, P; Zanchetti, A | 1 |
| Barlattani, M; Filippello, CP; Leone, G; Mammarella, A; Mariani, AR; Paoletti, V | 1 |
| Canby, CA; Tomanek, RJ | 1 |
| Dworkin, LD; Feiner, HD; Grosser, M; Parker, M; Ullian, M | 1 |
| Dallocchio, M; Gosse, P; Gourgon, R | 1 |
| Weinberger, MH | 4 |
| Acosta-Barrios, TN; Leary, WP; Reyes, AJ; van der Byl, KV | 1 |
| Ambrosioni, E; Borghi, C; Boschi, S; Costa, FV | 1 |
| MacGregor, GA; Markandu, ND; Sagnella, GA; Smith, SJ | 1 |
| Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W | 1 |
| Mimran, A; Ribstein, J | 2 |
| Cervenka, JH; Dinh, T; O'Connor, DT; Takiyyuddin, MA; Witztum, JL | 1 |
| Esser, H; Heck, I; Lüderitz, B; Müller, HM | 1 |
| Lacourcière, Y; Provencher, P | 1 |
| Brunkhorst, R; Koch, K; Kühn, K; Schmidt, FW; Wrenger, E | 1 |
| Cheung, DG; Gasster, JL; Weber, MA | 1 |
| Botta, GF; Buoninconti, R; De Cesaris, R; Santucci, A | 1 |
| Antonicelli, R; Bossini, A; Botta, GF; Paciaroni, E; Raffaelli, S; Zingaretti, P | 1 |
| Anderson, S; Brenner, BM; Garcia, DL; Rennke, HG | 1 |
| Botta, GF; Magenta, M; Malacco, E; Noia, E; Renesto, E; Sartini, C | 1 |
| Gagné, C; Lacourcière, Y | 2 |
| Lion, MF; Lion, R; Nascimento, LO; Pesquisadores, E | 1 |
| Giorgy, D; Mansur, AP; Nascimento, LO; Nicolau, JC; Pierri, H; Ramires, JA; Solimene, MC; Wajngarten, M | 1 |
| Kin, T; Vallance-Owen, J; Woo, J; Woo, KS | 1 |
| Ambrosioni, E; Borghi, C; Boschi, S; Costa, FV; Mussi, A | 1 |
| Vallance-Owen, J; Woo, J; Woo, KS | 1 |
| Brest, AN | 1 |
| Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E | 1 |
| Ayers, CR; Baker, KM; Lehman, MR; Weaver, BA | 1 |
| Johnson, AL; Price, WA; Stump, JM; Vavala, RF; Wong, PC | 1 |
| Bulpitt, CJ; Fletcher, AE; Hill, JF | 1 |
| Baumgart, P; Tenschert, W; Vetter, H | 2 |
| Damkjaer Nielsen, M; Giese, J; Ibsen, H; Leth, A; Nielsen, F; Rasmussen, S | 3 |
| Thind, GS | 1 |
| Giudicelli, JF; Mattei, A; Richer, C | 1 |
| Cobbol, C; Katz, LA | 1 |
| Leary, WP; Maharaj, B; van der Byl, KV | 1 |
| Battisti, P; Cugini, P; Di Palma, L; Di Veroli, C | 1 |
| Scapellato, L; Stornello, M; Valvo, E | 1 |
| Ambrosioni, E; Borghi, C; Costa, FV; Mussi, A | 3 |
| Forattini, C; Perin, S | 1 |
| Abitbol, JP; Garay, R; Ollivier, JP; Senn, N | 1 |
| Freis, ED | 1 |
| Hardarson, T; Kristinsson, A; Palsson, K; Petursson, MK; Snorrason, SP; Thorgeirsson, G | 1 |
| Iino, S; Inoue, S; Shionoiri, H | 1 |
| Graney, WF; Nichola, PS; Thurm, RH | 1 |
| Popa, V | 1 |
| Aranda-Lara, P; Cabello, M; Frutos, M; Gras-Balaguer, X; López de Novales, E; Martín-Reyes, G; Valera, A | 1 |
| Zhu, YC | 1 |
| Agabiti-Rosei, E; Buoninconti, R; Cagli, V; Carotti, A; Corea, L; Innocenti, P; Malerba, M; Muiesan, G; Paciaroni, E; Pirrelli, A | 1 |
| Bracchetti, D; Brunelli, A; Cantelli, I; Sangiorgio, P | 1 |
| Brown, B; Bulpitt, CJ; Croog, SH; Jenkins, CD; Klerman, GL; Levine, S; Testa, MA; Williams, GH | 1 |
| Mondal, S; Pandhi, P; Sharma, BK; Sharma, PL; Wahi, PL | 1 |
| Katz, LA; Kirkendall, WM; Koeppe, PR; Ruoff, GE; Sapir, DG; Tuck, ML | 1 |
| Bricaud, H; Clementy, J; Justal, A; Mazaud, C; Schwebig, A | 1 |
| Baulac, L; Creisson, C; Lenfant, B | 1 |
| Balcells, A; Gaya, J; Ingelmo, M; Rabinad, E; Rivera, F | 1 |
| Andersen, H; Botta, G; Galasse, R; Hill, JF | 1 |
| de la Calle, H; Dominguez, JR; Hurtado, A; Robles, RG; Sancho-Rof, J | 1 |
| Pitterle, ME; Schmidt, GR; Schuna, AA | 1 |
| Carnovali, M; Crespi, E; Missaglia, A; Panozzo, M; Ponti, G | 1 |
| Schoenberger, JA; Wilson, DJ | 1 |
| Sano, T; Tarazi, RC | 1 |
| Tuck, ML | 1 |
| Bobadilla, NA; Calleja, C; Cermeño, JL; Gabbai, FB; Herrera-Acosta, J; Romero, L; Tapia, E | 1 |
| Ambrosioni, E; Borghi, C; Costa, FV | 2 |
| Childs, M; Lancrenon, S; Languillat, JM; Mattei, A; Millet, B; Schwebig, A; Stephan, A; Steru, D | 1 |
| Bernard, F; Drivet-Perrin, J; Poggi, L; Sambuc, R; Vaisse, B | 1 |
| Asmar, RG; Hugue, CJ; Laurent, S; Pannier, BM; Safar, ME; Safavian, A | 1 |
| Ardesch, HG; De Bruijn, JH; Meijer, JL; Van Rooijen, JC | 1 |
| Baulac, L; Kayanakis, JG | 1 |
| Holzgreve, H; Osterkorn, K; Runge, J | 1 |
| Ferguson, RK; Koplin, JR; Oren, A; Riley, LJ; Rotmensch, HH; Tadros, SS; Vlasses, PH | 1 |
| Ferguson, RK; Fruncillo, RJ; Koplin, JR; Rotmensch, HH; Swanson, BN; Vlasses, PH | 1 |
| Andrén, L; Hansson, L; Karlberg, BE; Nilsson, OR; Ohman, P; Svensson, A | 1 |
| Achilli, L; Caporicci, D; Mori, A; Pepi, R | 1 |
| Garcia-Alves, M; Macieira-Coelho, E; Reis-Valle, A | 1 |
| Alfiero, R; Padula, A; Rizzo, A; Russo, L; Strozzi, C | 1 |
| Rosenfeld, JB; Traub, YM | 1 |
| Garrido Peralta, M; Gras, X; Ocón, J; Oliván, J; Rodicio, JL; Rodríguez Alvarez, J; Ruilope, L; Seco Vasco, J | 1 |
| Cressman, M; Tarazi, RC | 1 |
| Davies, RO; Irvin, JD; Kramsch, DK; Moncloa, F; Walker, JF | 1 |
| Girchev, R; Piryova, B | 1 |
| Giese, J; Ibsen, H; Nielsen, MD; Rasmussen, S | 1 |
| Kramsch, DM; Kulaga, SF; Walker, JF | 1 |
| Kulaga, SF; McFate Smith, W; Moncloa, F; Pingeon, R; Walker, JF | 1 |
| Heuer, LJ | 1 |
| Cervoni, P; Chan, PS; Ronsberg, MA | 2 |
| Bauer, JH | 1 |
| Casley, DJ; Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 1 |
| Antonaccio, MJ; Cheung, HS; Cushman, DW; Murthy, VS; Ondetti, MA; Rubin, B | 1 |
| Crantz, FR; Dluhy, RG; Hollenberg, NK; Levine, L; Moore, TJ; Sasahara, AA; Swartz, SL; Williams, GH | 1 |
| Julius, S; Nicholls, MG; Zweifler, AJ | 1 |
| Chiarini, C; Degli Esposti, E; Fusaroli, M; Masi, A; Santoro, A; Sturani, A; Zuccalà, A; Zucchelli, P | 1 |
| Greminger, P; Havelka, J; Lüscher, T; Siegenthaler, W; Studer, A; Vetter, H; Vetter, W; Wollnik, S | 1 |
| Ferguson, RK; Mojaverian, P; Rotmensch, HH; Swanson, BN; Vlasses, PH | 1 |
| Cervoni, P; Chan, PS; Goldstein, B; Herzlinger, H; Lai, FM; Tanikella, T | 1 |
| Ferguson, RK; Rotmensch, HH; Smith, JB; Swanson, BN; Vlasses, PH | 1 |
| Chernow, B; Coleman, MD; Lake, CR; Zaloga, GP; Ziegler, MG | 1 |
| Damkjaer Nielsen, M; Giese, J; Ibsen, H; Leth, A; Rasmussen, S | 1 |
| Carver, LA; Lee, CH; Strosberg, AM | 1 |
| Coleman, RD; Johnson, A; Mahapatra, RK; Thind, GS | 1 |
| Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S | 1 |
| Muldowney, FP; Ryan, E | 1 |
| Andrén, L; Hansson, L; Svensson, A | 1 |
| Kirschbaum, J; Perlman, S | 1 |
| Moyer, JH | 1 |
| Del Nero Júnior, E; Estrella, LA; Lima, EV; Nassif, M; Praxedes, JN; Puppi, EJ; Savioli, RM; Stoeber, GH | 1 |
| Asplund, J; Aurell, M; Conradsson, T; Delin, K; Forslund, T; Frithz, G; Fyhrquist, F; Herlitz, H; Karlberg, B; Ohman, P | 1 |
| Alves Filho, G; Carvalho, OM; Guariento, ME; Rizzalitti, F; Rocha, JC; Santos, TC | 1 |
| Maciel, R; Spritzer, N; Spritzer, TS; Wolmeister, H | 1 |
| Perlman, S; Sieh, DH | 1 |
| Lund-Johansen, P; Omvik, P | 1 |
| Dias, GC | 1 |
| Assad, JE; Castilho, F; Faria Neto, A; Levigard, RM; Santos Neto, FB | 1 |
| Freslon, JL; Giudicelli, JF; Richer, C | 1 |
| Alsina, J; Balcells Gorina, A; Ingelmo Morin, M; Martinez Amenos, A; Rabinad Estrada, E | 1 |
| Andrén, L; Asplund, J; Hansson, L; Karlberg, B; Ohman, P; Svensson, A | 1 |
| Asplund, J; Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S | 2 |
| Gu, DG; Gu, TH; Pan, XX; Shen, JQ; Wang, H; Wu, SW; Xie, L; Zhao, GS | 1 |
| Banks, RA; Bayliss, J; Jones, JC; MacGregor, GA; Markandu, ND; Roulston, JE | 1 |
| de Bruyn, JH; Derkx, FH; Man in't Veld, AJ; Schalekamp, MA; Wenting, GJ; Woittiez, AJ | 1 |
| Alexander, JC; Burke, JF; Ferguson, RK; Koplin, JR; Shirinian, A; Vlasses, PH | 1 |
| Antonaccio, MJ; Horovitz, ZP; Rubin, B | 1 |
| Alves Filho, G; de Almeida, FA; Kohlmann Junior, O; Ramos, OL; Ribeiro, AB; Stella, SR | 1 |
| Kaplan, HR; Smith, RD; Tessman, DK | 1 |
| Damkjaer Nielsen, M; Giese, J; Rasmussen, S | 1 |
| Heidland, A; Röckel, A | 1 |
| el-Mehairy, MM; Hamza, S; Ramadan, M; Shaker, A; Tadros, SS | 1 |
| Lüscher, T; Siegenthaler, W; Studer, A; Vetter, W | 1 |
| Laroche, B; Mimran, A; Targhetta, R | 1 |
| Baum, T; Glennon, JC; Vander Vliet, G | 1 |
| Aberg, H; Frithz, G; Mörlin, C | 1 |
| Ferguson, RK; Koplin, JR; Mojaverian, P; Swanson, BN; Vlasses, PH | 1 |
| Carlier, B; De Plaen, JF; Van Ypersele de Strihou, C | 1 |
| Ferguson, RK; Rotmensch, HH; Vlasses, PH | 1 |
| Lunn, J; Moser, M | 1 |
| Broer, M; Duda, SG; Filatova, NP; Metelitsa, VI; Mukhamedzhanova, GF; Ostrovskaia, TP; Siegrist, J; Vygodin, VA | 1 |
| Garcon, D; Jourdheuil-Rahmani, D; Masset, D; Rahmani, R; Rolland, PH | 1 |
| Canby, CA; Kawai, M; Rongish, BJ; Schraeger, JA; Tomanek, RJ | 1 |
| Pauly, NC; Safar, ME | 1 |
| Chanudet, X; Janin, G; Madonna, O; Mayaudon, H | 1 |
| Duda, SG; Filatova, NP; Metelitsa, VI; Ostrovskaia, TP; Vygodin, VA | 1 |
| Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR | 1 |
| Barlatier, A; Bodard, H; Charpiot, P; Faye, MM; Friggi, A; Ghiringhelli, O; Guillou, J; Latrille, V; Piquet, P; Rolland, PH | 1 |
| Fogari, R; Lusardi, P; Motolese, M; Tettamanti, F; Tettamanzi, D; Zoppi, A | 1 |
| Fenichel, RR; Lipicky, RJ | 1 |
| Belz, GG; Breithaupt, K; Erb, K | 1 |
| Bielan, B | 1 |
| Berne, C; Lind, L; Lithell, H; Pollare, T | 1 |
| Geppert, R; Hänseler, T; Jansen, W; Mathas, B; Tauchert, M; Weidmann, B | 1 |
| Lou, ZJ; Sun, XL; Zhu, GL | 1 |
| Delage, Y; Gressin, V; Madonna, O; Poggi, L; Renucci, JF; Vaïsse, B | 1 |
| Malacco, E | 1 |
| Chideckel, EW; Stevenson, JG | 1 |
| Zhao, D | 1 |
| Barnes, P; Hanton, G; Shepperson, NB; Walley, R | 1 |
| Escobar, E; Medina, E; Roessler, E; Román, O; Valdés, G; Zarate, H | 1 |
| Grupp, LA; Harding, S; Robertson, JM | 1 |
| Cushman, WC; Freis, ED; Fye, C; Gottdiener, J; Hamburger, RJ; Kochar, MS; Lakshman, R; Massie, BM; Materson, BJ; Reda, DJ | 1 |
| Beck-Nielsen, H; Faergeman, O; Gall, MA; Gerdes, LU; Hommel, EE; Lauritzen, M; Mathiesen, ER; Rossing, P; Skøtt, P; Vølund, A | 1 |
| Franco, RJ; Martin, LC; Velasco-Cornejo, IF | 1 |
| Darioli, R; Greminger, P; Riesen, W; Simeon-Dubach, D; Waeber, B; Wunderlin, R | 1 |
| Chil'tsov, VV; Ignat'ev, VG; Kukes, VG; Pavlov, SS; Pavlova, LI; Privalov, AN; Rumiantsev, AS | 1 |
| Bagdade, JD; Buchanan, WF; Lithell, H; Pollare, T | 1 |
| Asmar, R; Bénétos, A; Gautier, S; Laflèche, A; Safar, A; Safar, ME | 1 |
| Brault, Y; Chastang, C; Di Perri, T; Guez, D; Laurandin, I; Luccioni, R; Redon, J; Sever, PS | 1 |
| Anson, O; Neumann, L; Paran, E | 1 |
| Himmel, W; Kochen, MM; Lönker, B | 1 |
| Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Holzgreve, H; Middeke, M; Richter, WO; Schwandt, P | 1 |
| Fukui, M; Shou, I; Tang, Z; Tomino, Y; Wang, LN | 1 |
| Broer, M; Duda, SG; Filatova, NP; Metelitsa, VI; Mukhamedzhanova, GF; Ostrovskaia, TP; Siegrist, I; Vygodin, VA | 1 |
| Beyer, KH; Follansbee, MH; Griffith, JW; Vesell, ES | 1 |
| Buttar, HS | 1 |
| Fukui, M; Shou, I; Suzuki, S; Tomino, Y; Wang, LN | 1 |
| Gong, L; Liu, G; Liu, L; Staessen, JA; Wang, JG | 1 |
| Augier, T; Bescond, A; Chareyre, C; Charpiot, P; Fraterno, M; Garçon, D; Rolland, PH | 1 |
| Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ | 1 |
| Klein, G | 1 |
| Mion Júnior, D; Santello, JL | 1 |
| Atkinson, J; Capdeville-Atkinson, C; Chillon, JM; Giummelly, P; Lartaud-Idjouadiene, I; Marque, V; Niederhoffer, N | 1 |
| Ritz, E; Schwenger, V; Zeier, M | 1 |
| Fitilev, SB; Ol'binskaia, LI; Potapova, GN; Pukhlianko, ME; Sergeeva, TE; Sizova, ZhM; Zheleznykh, EA | 1 |
| Gong, L; Liu, L; Staessen, JA; Wang, JG | 1 |
| Cifková, R; Compagnone, D; Hejl, Z; Nakov, R; Novozámská, E; Petrzílková, Z; Poledne, R; Stávek, P | 1 |
| Akhmetov, KZh; Biiasilov, NS; Teĭblium, MM; Zaslavskaia, RM | 1 |
| Bart, BIa; Dergunova, EN; Larina, VN | 1 |
| Birkenhäger, WH; Fagard, RH; Gong, L; Liu, L; Staessen, JA; Wang, JG | 1 |
| Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Bertocchi, F; Carretta, R; Di Somma, S; Malacco, E; Mugellini, A; Palatini, P; Piazza, S | 1 |
| Leenen, FH; Ruzicka, M | 1 |
| Rizzoni, D; Rosei, EA | 1 |
| Dierkes, J; Luley, C; Rading, A; Westphal, S | 1 |
| Dinç, E; Ustündağ, O | 1 |
| Gavras, I; Rosenthal, T | 1 |
| Catalá Icardo, M; Martínez Calatayud, J; Tomsů, D | 1 |
| Brel', UA; Chaliabi, TA; Kapustin, IO; Marchenko, IV; Nedogoda, SV; Prokhorova, EA; Tsoma, VA | 1 |
| Alcaraz, A; Atucha, NM; Evangelista, S; García-Estañ, J; Navarro, EG; O'Valle, F; Ortiz, MC; Vargas, F | 1 |
| Buikema, H; Schoemaker, RG; van Gilst, WH; van Veldhuisen, DJ; Westendorp, B | 1 |
| Nedogoda, SV | 1 |
| Brel', UA; Chaliabi, TA; Marchenko, IV; Nedogoda, SV; Prokhorova, EA; Tsoma, VV | 1 |
| Duan, G; He, Z; Huang, T; Shao, L; Yang, B; Zheng, X | 1 |
| Bertoluci, MC; Oliveira, FR; Schmid, H; Schmidt, A; Thomazelli, FC; Uebel, D | 1 |
| Malacco, E; Parati, G; Zanchetti, A | 1 |
| Agharazii, M; Larivière, R; Lebel, M; Rodrigue, ME | 1 |
| Borghi, C; Cicero, AF | 1 |
| Jendeková, L; Kojsová, S; Pechánová, O; Sládková, M | 1 |
| Bai, Y; Chen, J; Fan, X; Fu, C; Han, Y; Hui, R; Li, W; Shi, Y; Song, X; Sun, K; Wang, H; Wang, Y; Wu, H; Xin, Y; Yang, T; Zhou, X | 1 |
| CAO, ZX; DU, X; HOU, GS; LI, DX; LIU, FS; QI, RP; SONG, SM; WANG, GL; WANG, LG; WU, SL; XING, AJ; YU, Q | 1 |
| Brody, R; Grossman, E; Peleg, E; Sharabi, Y | 1 |
| Malacco, E; Omboni, S; Parati, G | 1 |
| Carlucci, G; Di Federico, L; Iuliani, P | 1 |
| Cameron, A; Ewen, M; Laing, RO; van Mourik, MS | 1 |
| Hosseini, F; Mahmoudian, M; Nemati, F; Rahbar-Roshandel, N; Shafiei, M | 1 |
| Fan, X; Harris, RC; Takahashi, T; Wang, S; Yang, H; Yang, S; Zhang, MZ | 1 |
| Chen, CC; Dahly-Vernon, AJ; Dunn, KM; Ledbetter, SR; Murphy, SR; Roman, RJ; Williams, JM | 1 |
| Chen, GL; Chen, ZK; Lu, M; Wang, LB; Wang, LD; Yang, MC; Zhai, PJ | 1 |
| Gumustas, M; Kurbanoglu, S; Ozkan, SA | 1 |
| Agabiti-Rosei, E; Manolis, A; Omboni, S; Zava, D | 1 |
| Borghi, C; Omboni, S | 2 |
| Chen, DY; Liu, TT; Wang, JL; Xiang, LL | 1 |
| Arca, M; Berra, S; Bucci, M; Calabrò, P; Fulgheri, PL; Ghione, S; Modesti, PA; Omboni, S; Pirvu, O; Popescu, E; Portaluppi, F; Pozzilli, P; Taddei, S; Velican, VG; Villani, GQ; Vladoianu, M; Volpe, M | 1 |
| Brusotti, G; Caprini, C; Del Bubba, M; Furlanetto, S; Innocenti, M; Orlandini, S; Pasquini, B | 1 |
| Borghi, C; Napoli, C; Omboni, S | 1 |
| Bananezhad, A; Ganjali, MR; Karimi-Maleh, H; Norouzi, P | 1 |
| Agabiti-Rosei, E; Borghi, C; Malacco, E; Manolis, A; Modesti, PA; Napoli, C; Omboni, S; Parati, G | 1 |
| Abbas, SS; Fayed, AS; Marzouk, HM; Rezk, MR | 2 |
| de Moura Leão, MF; de Oliveira, LFS; Duarte, JA; Machado, MM; Piccoli, JDCE; Sauzen, PD | 1 |
| Mahrouse, MA | 1 |
| Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M | 1 |
| Bryniarski, P; Marcinkiewicz, J; Nazimek, K | 1 |
| Bao, M; Li, J; Song, Y; Wu, S | 1 |
| Fan, TY; Li, ZS; Qian, HN | 1 |
19 review(s) available for captopril and hydrochlorothiazide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Angiotensin-converting enzyme inhibition as first-line treatment for hypertension.
Topics: Amiloride; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Perindopril | 1992 |
The treatment of moderate to severe hypertension with ACE inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Atenolol; Captopril; Double-Blind Method; Drug Therapy, Combination; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Multicenter Studies as Topic; Quinapril; Tetrahydroisoquinolines | 1990 |
Spironolactone in the treatment of hypertension: a review.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Renin-Angiotensin System; Spironolactone | 1986 |
Captopril and hydrochlorothiazide: rationale for their combination.
Topics: Captopril; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Metabolism | 1987 |
Enalapril worldwide experience.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Cell Count; Blood Pressure; Captopril; Dipeptides; Drug Evaluation; Drug Therapy, Combination; Enalapril; Enalaprilat; Humans; Hydrochlorothiazide; Hypertension; Peptidyl-Dipeptidase A; Posture; Propranolol; Renin-Angiotensin System | 1984 |
Role of angiotensin converting enzyme inhibitors in essential and renal hypertension. Effects of captopril and enalapril on renin-angiotensin-aldosterone, renal function and hemodynamics, salt and water excretion, and body fluid composition.
Topics: Body Fluids; Captopril; Dipeptides; Drug Evaluation; Enalapril; Glomerular Filtration Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Potassium; Proline; Renin-Angiotensin System; Sodium; Teprotide | 1984 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa; Patient Compliance; Prazosin; Proteinuria; Renin-Angiotensin System; Reserpine; Spironolactone | 1984 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Dogs; Hemodynamics; Hydralazine; Hydrochlorothiazide; Hypertension; Kallikreins; Kidney; Proline; Prostaglandins; Rabbits; Rats; Renin; Sodium | 1980 |
[Congenitally corrected transposition of the great vessels in adulthood. The value of noninvasive study methods].
Topics: Captopril; Cardiac Catheterization; Cough; Diagnosis, Differential; Drug Therapy, Combination; Dyspnea; Echocardiography; Electrocardiography; Humans; Hydrochlorothiazide; Male; Middle Aged; Tomography, X-Ray Computed; Transposition of Great Vessels | 1994 |
An overview of the influence of ACE inhibitors on fetal-placental circulation and perinatal development.
Topics: Amniotic Fluid; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Combinations; Embryonic and Fetal Development; Female; Fetus; Humans; Hydrochlorothiazide; Kidney; Placental Circulation; Pregnancy; Rabbits; Rats; Renin-Angiotensin System | 1997 |
Combination therapy as first-line treatment of arterial hypertension.
Topics: Antihypertensive Agents; Atenolol; Captopril; Diltiazem; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Prazosin; Treatment Outcome | 2002 |
Combination therapy as first-line treatment for hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors | 2004 |
Zofenopril plus hydrochlorothiazide: Combination therapy for the treatment of mild to moderate hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 2006 |
Fixed combination of zofenopril plus hydrochlorothiazide in the management of hypertension: a review of available data.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Diseases; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Severity of Illness Index; Treatment Outcome | 2006 |
Zofenopril plus hydrochlorothiazide fixed combination in the treatment of hypertension and associated clinical conditions.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Metabolic Diseases | 2009 |
Zofenopril plus hydrochlorothiazide combination in the treatment of hypertension: an update.
Topics: Animals; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Captopril; Cardiovascular Diseases; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Practice Guidelines as Topic; Risk Factors | 2014 |
Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized "Z" Studies.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; C-Reactive Protein; Captopril; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Inflammation Mediators; Irbesartan; Lipids; Male; Middle Aged; Pulse Wave Analysis; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Vascular Stiffness | 2017 |
Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Kidney Diseases; Treatment Outcome | 2019 |
158 trial(s) available for captopril and hydrochlorothiazide
| Article | Year |
|---|---|
Long-term effects of captopril (SQ14 225) on blood-pressure and hormone levels in essential hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Proline; Renin | 1979 |
Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Proline; Renin | 1979 |
[Systolic hypertension in the elderly: Chinese trial (syst-China). Interim report].
Topics: Age Factors; Aged; Blood Pressure; Captopril; China; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Morbidity; Nitrendipine; Patient Compliance; Systole | 1992 |
Quality of life in hypertensives treated with atenolol or captopril: a double-blind crossover trial.
Topics: Adult; Aged; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Quality of Life | 1992 |
[Effect of hydrochlorothiazide on various components of the kinin system and plasma renin activity in patients with arterial hypertension treated with captopril].
Topics: Adult; Blood Pressure; Captopril; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kallikrein-Kinin System; Kininogens; Male; Middle Aged; Peptidyl-Dipeptidase A; Prekallikrein; Renin | 1992 |
[Captopril in mild and moderate arterial hypertension resistant to diuretic therapy. A multicenter study].
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium | 1992 |
[An open comparative study of captopril + hydrochlorothiazide versus chlorthalidone for the treatment of mild and moderate primary hypertension].
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Chi-Square Distribution; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1992 |
Angiotensin-converting enzyme inhibition as first-line treatment for hypertension.
Topics: Amiloride; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Perindopril | 1992 |
A "lipo-protective" effect of a fixed combination of captopril and hydrochlorothiazide in antihypertensive therapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cholesterol; Drug Combinations; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hyperlipidemias; Hypertension; Lipid Metabolism; Lipoproteins, HDL; Male; Middle Aged; Prospective Studies; Quality of Life | 1992 |
Placebo-controlled comparison of captopril, metoprolol, and hydrochlorothiazide therapy in non-insulin-dependent diabetic patients with primary hypertension.
Topics: Aged; Captopril; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Hypoglycemic Agents; Lipids; Male; Metoprolol; Middle Aged | 1992 |
Ambulatory blood pressure monitoring for the assessment of nicardipine as a third drug in severe essential hypertension.
Topics: Adult; Aged; Ambulatory Care; Blood Pressure Determination; Capsules; Captopril; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nicardipine | 1992 |
Controlling hypertension: lisinopril-hydrochlorothiazide vs captopril-hydrochlorothiazide. An Italian multicentre study.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Italy; Lisinopril; Male; Middle Aged | 1991 |
Treating mild-to-moderate hypertension: a comparison of lisinopril-hydrochlorothiazide fixed combination with captopril and hydrochlorothiazide free combination.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged | 1991 |
The treatment of moderate to severe hypertension with ACE inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Atenolol; Captopril; Double-Blind Method; Drug Therapy, Combination; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Multicenter Studies as Topic; Quinapril; Tetrahydroisoquinolines | 1990 |
Double-blind study of dilevalol and captopril, both in combination with hydrochlorothiazide, in patients with moderate to severe hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged | 1990 |
Assessment of antihypertensive efficacy of perindopril: results of double-blind multicenter studies versus reference drugs.
Topics: Amiloride; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Perindopril | 1991 |
Angiotensin converting enzyme inhibitors as initial monotherapy in severe hypertension. Quinapril and captopril.
Topics: Administration, Oral; Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Middle Aged; Quinapril; Tetrahydroisoquinolines | 1991 |
Captopril and hydrochlorthiazide--a safe antihypertensive for use in general practice?
Topics: Aged; Antihypertensive Agents; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Male; Middle Aged | 1991 |
[Fixed drug combination of ACE inhibitor plus diuretic. Results of an open multicenter study for the treatment of hypertension].
Topics: Adult; Blood Pressure; Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1991 |
Comparative effects of converting enzyme inhibition and conventional therapy in hypertensive non-insulin dependent diabetics with normal renal function.
Topics: Aged; Albuminuria; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Middle Aged | 1991 |
Once vs twice daily administration of a fixed combination of captopril plus hydrochlorothiazide in essential hypertension: a double-blind crossover study in known responders to a standard combination.
Topics: Adult; Aged; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic | 1991 |
Captopril versus captopril plus hydrochlorothiazide for essential hypertension in Koreans.
Topics: Antihypertensive Agents; Captopril; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Korea; Male; Middle Aged | 1991 |
Treatment of hypertension in the elderly: effects on blood pressure, heart rate, and physical fitness.
Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Captopril; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Physical Endurance; Physical Fitness | 1991 |
[Captopril and hydrochlorothiazide for the treatment of arterial hypertension in the elderly].
Topics: Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Rate; Hematologic Tests; Humans; Hydrochlorothiazide; Hypertension; Kidney Function Tests; Male; Middle Aged | 1991 |
Sodium restriction in hypertensive patients treated with a converting enzyme inhibitor and a thiazide.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Sodium | 1991 |
A controlled study of the effects of aerobic exercise on antihypertensive drug requirements of essential hypertensive patients in the general practice setting.
Topics: Adolescent; Adult; Blood Pressure; Captopril; Exercise Therapy; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1991 |
[Captopril in single doses in the treatment mild-moderated arterial hypertension].
Topics: Adult; Aged; Captopril; Clinical Protocols; Diastole; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Multicenter Studies as Topic; Systole | 1990 |
Self-reported side effects from antihypertensive drugs. A clinical trial. Quality of Life Research Group.
Topics: Adult; Age Factors; Aged; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Educational Status; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Multicenter Studies as Topic; Propranolol; Quality of Life; Random Allocation; United States | 1990 |
Moderate sodium restriction, angiotensin converting enzyme inhibition, and thiazide diuretic in the management of essential hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Diet, Sodium-Restricted; Diuretics; Double-Blind Method; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Random Allocation; Renin; Sodium; Sodium Chloride Symporter Inhibitors | 1989 |
[Perindopril: first-line treatment of arterial hypertension].
Topics: Adolescent; Adult; Aged; Amiloride; Antihypertensive Agents; Atenolol; Captopril; Clinical Trials as Topic; Diuretics; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Multicenter Studies as Topic; Perindopril; Random Allocation | 1989 |
[Efficacy and tolerability of captopril-hydrochlorothiazide vs amiloride-hydrochlorothiazide combination in mild to moderate arterial hypertension].
Topics: Aged; Amiloride; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Time Factors | 1989 |
ACE inhibitors in mild to moderate hypertension: comparison of lisinopril and captopril administered once daily. French Cooperative Study Group.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Multicenter Studies as Topic; Random Allocation | 1989 |
Blood pressure and metabolic responses to hydrochlorothiazide, captopril, and the combination in black and white mild-to-moderate hypertensive patients.
Topics: Black People; Blood Glucose; Blood Pressure; Captopril; Cholesterol; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Potassium; Proline; Uric Acid; White People | 1985 |
Effects of captopril, hydrochlorothiazide, and their combination on timed urinary excretions of water and solutes.
Topics: Adult; Captopril; Chlorides; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Magnesium; Male; Placebos; Proline; Sodium; Uric Acid; Water-Electrolyte Balance | 1985 |
Captopril and hydrochlorothiazide in the fixed combination multicenter trial.
Topics: Adult; Blood Pressure; Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Proline; Pulse | 1985 |
Differing dosages of captopril and hydrochlorothiazide in the treatment of hypertension: long-term effects metabolic values and intracellular electrolytes.
Topics: Adult; Aged; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lymphocytes; Male; Middle Aged; Potassium; Proline; Random Allocation; Sodium | 1985 |
Captopril: contrasting effects of adding hydrochlorothiazide, propranolol, or nifedipine.
Topics: Blood Pressure; Body Weight; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Posture; Proline; Propranolol; Renin; Time Factors | 1985 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil | 1985 |
Selective alpha-blockade versus angiotensin-converting enzyme inhibition as initial antihypertensive therapy. Effects on circulating lipoproteins.
Topics: Adult; Aged; Apolipoproteins; Captopril; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Prazosin; Random Allocation | 1989 |
[Captopril versus digoxin in the treatment of mild to moderately severe heart failure].
Topics: Blood Pressure; Captopril; Chronic Disease; Clinical Trials as Topic; Digoxin; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Stroke Volume | 1989 |
Comparative effects of zofenopril and hydrochlorothiazide on office and ambulatory blood pressures in mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Captopril; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monitoring, Physiologic | 1989 |
A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension.
Topics: Blood Glucose; Blood Pressure; Captopril; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Insulin; Lipids; Lipoproteins; Male; Middle Aged; Random Allocation | 1989 |
[Assessment of tolerability and antihypertensive efficacy of aceplus mite (captopril (CPT) 50 mg + hydrochlorothiazide (HCTZ) 15 mg): a double-blind study vs. HCTZ in diabetic hypertensive patients. A report on three treatments].
Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Diabetes Complications; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Random Allocation | 1989 |
[Evaluation of the efficacy and tolerability of a fixed dose combination of captopril (CPT) 50 mg and hydrochlorothiazide (HCTZ) 15 mg in the elderly].
Topics: Aged; Aged, 80 and over; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Randomized Controlled Trials as Topic | 1989 |
Influence of zofenopril and low doses of hydrochlorothiazide on plasma lipoproteins in patients with mild to moderate essential hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Apolipoproteins; Captopril; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Randomized Controlled Trials as Topic | 1989 |
[Treatment of mild and moderate hypertension with the use of captopril alone or combined with hydrochlorothiazide. A multicenter study].
Topics: Adolescent; Adult; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic | 1989 |
[Efficacy of captopril in the treatment of mild and moderate hypertension in patients over 60 years of age].
Topics: Aged; Aged, 80 and over; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1989 |
Antihypertensive efficacy and influence on physical activity of three different treatments in elderly hypertensive patients.
Topics: Aged; Amiloride; Antihypertensive Agents; Captopril; Drug Evaluation; Drug Therapy, Combination; Drug Tolerance; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Physical Endurance | 1989 |
A single-blind, randomized, cross-over study of angiotensin-converting enzyme inhibitor and triamterene and hydrochlorothiazide in the treatment of mild to moderate hypertension in the elderly.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Random Allocation; Triamterene | 1987 |
Modifications of intra- and extracellular sodium and potassium. A possible mechanism for the antihypertensive action of captopril and hydrochlorothiazide.
Topics: Adult; Antihypertensive Agents; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Potassium; Sodium | 1985 |
Captopril versus hydrochlorothiazide/triamterene in mild-to-moderate hypertension in the elderly.
Topics: Aged; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Random Allocation; Triamterene | 1986 |
Enalapril maleate versus captopril. A comparison of the hormonal and antihypertensive effects.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Enalapril; Female; Hormones; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1985 |
Angiotensin converting enzyme inhibitors and quality of life: the European trial.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Prospective Studies; Quality of Life; Random Allocation | 1985 |
Converting enzyme inhibition in mild and moderate essential hypertension. I. Acute effects on blood pressure, the renin-angiotensin system and blood bradykinin after a single dose of captopril.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1985 |
Converting enzyme inhibition in mild and moderate essential hypertension. II.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Plasma Volume; Renin-Angiotensin System; Sodium | 1986 |
Pharmacokinetics and biological effects of captopril and hydrochlorothiazide after acute and chronic administration either alone or in combination in hypertensive patients.
Topics: Adult; Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Male; Middle Aged; Peptidyl-Dipeptidase A; Random Allocation; Renin | 1987 |
Metabolic and blood pressure effects of angiotensin converting enzyme inhibitors in mild-to-moderate American hypertensives.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hydrochlorothiazide; Hypertension | 1987 |
Treating black hypertensives with capozide.
Topics: Black People; Blood Pressure; Blood Urea Nitrogen; Captopril; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Uric Acid | 1988 |
A comparison of captopril and atenolol in addition to hydrochlorothiazide for the treatment of hypertension.
Topics: Adult; Atenolol; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension | 1988 |
[Comparison of the antihypertensive effectiveness of captopril in combination with various doses of hydrochlorothiazide].
Topics: Adult; Aged; Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic | 1988 |
[Antihypertensive effects of captopril, hydrochlorothiazide, alone or in combination, with different categories of essential hypertensive patients].
Topics: Biological Transport; Captopril; Drug Therapy, Combination; Erythrocytes; Humans; Hydrochlorothiazide; Hypertension; Iodohippuric Acid; Male; Middle Aged; Potassium; Sodium | 1988 |
Additive effects of moderate dietary salt reduction and captopril in hypertension.
Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Diet, Sodium-Restricted; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1988 |
Twenty-four-hour blood pressure monitoring in the evaluation of once daily treatment of essential hypertension.
Topics: Blood Pressure Determination; Captopril; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Monitoring, Physiologic | 1987 |
Captopril-related (and -induced?) asthma.
Topics: Asthma; Captopril; Drug Combinations; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Triamterene | 1987 |
[Clinical significance of using captopril compounds treating primary hypertension].
Topics: Adult; Captopril; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Sodium Chloride Symporter Inhibitors | 1987 |
Antihypertensive efficacy and tolerability of captopril in the elderly: comparison with hydrochlorothiazide and placebo in a multicentre, double-blind study.
Topics: Aged; Captopril; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Posture | 1987 |
The effects of antihypertensive therapy on the quality of life.
Topics: Adult; Aged; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Quality of Life; Random Allocation | 1986 |
Low-dose captopril in mild to moderate geriatric hypertension.
Topics: Age Factors; Aged; Black or African American; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1986 |
Comparative study of the efficacy and tolerance of capozide and moduretic administered in a single daily dose for the treatment of chronic moderate arterial hypertension.
Topics: Adolescent; Adult; Aged; Amiloride; Blood Pressure; Captopril; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1986 |
Captopril/hydrochlorothiazide combination in elderly patients with mild-moderate hypertension. A double-blind, randomized, placebo-controlled study.
Topics: Aged; Blood Pressure; Captopril; Clinical Trials as Topic; Creatinine; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Random Allocation | 1986 |
Neurohormonal responses to antihypertensive treatment with captopril or hydrochlorothiazide.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Dopamine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Potassium; Renin | 1986 |
Efficacy of captopril and hydrochlorothiazide administered once a day.
Topics: Blood Pressure; Captopril; Clinical Trials as Topic; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Time Factors | 1986 |
Influence of captopril on intracellular ions--a possible mode of action.
Topics: Adult; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Potassium; Sodium | 1986 |
Once-daily treatment of essential hypertension with captopril.
Topics: Adolescent; Adult; Blood Pressure; Captopril; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Placebos; Random Allocation; Time Factors | 1986 |
Specific patient challenge: the elderly hypertensive patient.
Topics: Aged; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male | 1987 |
Determination of the optimal dosage regimen of captopril + hydrochlorothiazide in the treatment of moderate arterial hypertension.
Topics: Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Evaluation; Humans; Hydrochlorothiazide; Hypertension; Random Allocation | 1987 |
Comparison of once and twice daily administration of captopril plus hydrochlorothiazide on 24 h blood pressure levels.
Topics: Blood Pressure; Captopril; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Humans; Hydrochlorothiazide; Hypertension; Random Allocation | 1987 |
Captopril plus hydrochlorothiazide once daily normalizes 24 h blood pressure in patients with essential hypertension.
Topics: Adult; Aged; Captopril; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1987 |
Comparative study of once-daily administration of captopril 50 mg, hydrochlorothiazide 25 mg and their combination in mild to moderate hypertension.
Topics: Adult; Aged; Captopril; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1987 |
Captopril in combination with hydrochlorothiazide: comparative efficacy vs perceived best therapy.
Topics: Captopril; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1987 |
Crossover comparison of captopril and propranolol as step 2 agents in hypertension.
Topics: Adult; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol | 1985 |
Effect of captopril and hydrochlorothiazide on the response to pressor agents in hypertensives.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Proline | 1985 |
Long-term effects of captopril and atenolol in essential hypertension.
Topics: Adult; Aged; Atenolol; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Time Factors | 1985 |
Antihypertensive efficacy of two low dosages of hydrochlorothiazide in patients treated with captopril.
Topics: Adult; Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1985 |
[Multicenter study of the efficacy of 3 antihypertensive regimens: captopril + hydrochlorothiazide, oxprenolol + hydrochlorothiazide, and alphamethyldopa + hydrochlorothiazide].
Topics: Adult; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Prospective Studies; Spain | 1985 |
The efficacy and safety of enalapril in moderate to severe essential hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Random Allocation; Statistics as Topic | 1984 |
Overall tolerance and safety of enalapril.
Topics: Captopril; Clinical Trials as Topic; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Global Health; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Leukopenia; Skin Diseases; Taste Disorders | 1984 |
Low-dose captopril for the treatment of mild to moderate hypertension. I. Results of a 14-week trial. Veterans Administration Cooperative Study Group on Antihypertensive Agents.
Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Drug Eruptions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Proteinuria | 1984 |
[Use of SQ 14225 in the treatment of essential arterial hypertension].
Topics: Adult; Aged; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1981 |
Low-dose captopril: its use in mild to moderate hypertension unresponsive to diuretic treatment.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Renin | 1982 |
Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Epoprostenol; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
The renin-angiotensin system during converting enzyme inhibition with captopril in patients with severe treatment-resistant hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Blood Pressure; Captopril; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol; Renin; Renin-Angiotensin System | 1984 |
Captopril, aldosterone and urinary kallikrein in primary hypertension.
Topics: Aldosterone; Angiotensin II; Captopril; Humans; Hydrochlorothiazide; Hypertension; Kallikreins; Proline; Renin-Angiotensin System | 1983 |
Use of angiotensin I to II converting enzyme inhibitor S.Q. 14225 (captopril), in moderate essential hypertension.
Topics: Adult; Captopril; Clinical Trials as Topic; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Proline | 1983 |
Captopril or atenolol in essential hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Random Allocation | 1983 |
Captopril and oxprenolol in a fixed combination with thiazide diuretics: comparison of their antihypertensive efficacy and metabolic effects.
Topics: Adult; Blood Pressure; Captopril; Chlorthalidone; Cholesterol; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Proline; Random Allocation | 1984 |
A long-term follow-up of patients with essential hypertension treated with captopril.
Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Female; Follow-Up Studies; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Dropouts; Proline; Propranolol; Time Factors | 1984 |
[Treatment of mild and moderate arterial hypertension with low doses of captopril].
Topics: Adult; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1984 |
[Captopril in mild or moderate systemic arterial hypertension].
Topics: Blood Pressure; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Proline | 1984 |
[Efficacy and safety of captopril in low doses, alone or combined with diuretics, in the treatment of mild or moderate arterial hypertension].
Topics: Aged; Blood Pressure; Captopril; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1984 |
[Efficacy and safety of low doses of captopril, alone or combined with diuretics in the treatment of mild or moderate hypertension].
Topics: Adult; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1984 |
Captopril and atenolol combined with hydrochlorothiazide in essential hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propanolamines; Renin-Angiotensin System | 1982 |
Comparison of captopril and hydrochlorothiazide alone and in combination in mild to moderate essential hypertension.
Topics: Blood; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1982 |
Racial differences in response to low-dose captopril are abolished by the addition of hydrochlorothiazide.
Topics: Black People; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Proline; Renin; White People | 1982 |
Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol.
Topics: Adult; Aged; Aldosterone; Body Weight; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Proline; Propranolol; Renin | 1982 |
Captopril, an orally active converting enzyme inhibitor, in the treatment of primary hypertension. A controlled long-term study with reference to initial plasma renin activity.
Topics: Adult; Aldosterone; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Random Allocation; Renin | 1981 |
Control of essential hypertension with captopril, an angiotensin converting enzyme inhibitor.
Topics: Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Time Factors | 1981 |
Comparison of captopril (SQ 14225) with hydrochlorothiazide in the treatment of essential hypertension.
Topics: Adult; Blood Pressure; Captopril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1981 |
Responses to captopril and hydrochlorothiazide in black patients with hypertension.
Topics: Adult; Black People; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; White People | 1982 |
[The effect of long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents on the quality of life in patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working
Topics: Adult; Antihypertensive Agents; Azerbaijan; Captopril; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Quality of Life; Russia; Statistics as Topic; Ukraine | 1995 |
Comparison of the efficacy and safety of trandolapril and captopril for 16 weeks in mild-to-moderate essential hypertension. Investigator Study Group.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Time Factors | 1994 |
[Comparison of the efficacy of enalapril + hydrochlorothiazide and captopril + hydrochlorothiazide combinations in mild-to-moderate arterial hypertension by ambulatory measurement of blood pressure].
Topics: Adult; Aged; Ambulatory Care; Blood Pressure Determination; Captopril; Double-Blind Method; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1995 |
[The long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents of patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working group of the Multicenter Captopr
Topics: Adult; Azerbaijan; Captopril; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propranolol; Quality of Life; Russia; Statistics as Topic; Time Factors; Ukraine | 1995 |
Reduction of salt intake during converting enzyme inhibitor treatment compared with addition of a thiazide.
Topics: Aged; Blood Pressure; Captopril; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium; Sodium, Dietary | 1995 |
Evaluation by 24-hour ambulatory blood pressure monitoring of efficacy of benazepril 20 mg plus hydrochlorothiazide 25 mg fixed combination as compared to captopril 50 mg [corrected] plus hydrochlorothiazide 25 mg fixed combination in treating mild to mod
Topics: Administration, Oral; Adult; Analysis of Variance; Antihypertensive Agents; Benzazepines; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Outpatients | 1994 |
Review of studies on the clinical pharmacodynamics of cilazapril.
Topics: Administration, Oral; Aged; Angiotensin I; Blood Pressure; Captopril; Cardiac Output; Cilazapril; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Enalapril; Female; Half-Life; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol | 1994 |
Long-term metabolic effects of antihypertensive drugs.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Glucose; Captopril; Cholesterol, HDL; Cross-Over Studies; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Insulin; Insulin Resistance; Lipids; Lipoproteins, VLDL; Male; Middle Aged | 1994 |
[Evaluation of the antihypertensive efficacy of lisinopril and captopril associated with hydrochlorothiazide by ambulatory measurement of arterial pressure].
Topics: Adult; Ambulatory Care; Antihypertensive Agents; Blood Pressure Determination; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Lisinopril; Male; Middle Aged | 1993 |
Combination therapy versus monotherapy in hypertensive patients: an Italian multicentre study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Italy; Lisinopril; Male; Middle Aged; Nitrendipine | 1993 |
Evaluation of cilazapril versus captopril in patients with mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Captopril; Cilazapril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome | 1994 |
[Systolic hypertension in the elderly: Chinese trial (Syst-China)--second interim report].
Topics: Captopril; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nitrendipine; Patient Compliance; Systole | 1993 |
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Clonidine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin | 1993 |
[The effect of captopril, metoprolol and hydrochlorothiazide therapy in patients with non-insulin-dependent diabetes (NIDDM) and primary hypertension. A double-blind, randomized cross-over study].
Topics: Aged; Captopril; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged | 1993 |
Captopril or conventional therapy in hypertensive type II diabetics. Three-year analysis.
Topics: Aged; Albuminuria; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Metoprolol; Middle Aged; Prospective Studies | 1993 |
Influence of combination of captopril and hydrochlorothiazide on plasma lipids, lipoproteins and apolipoproteins in primary hypertension.
Topics: Adolescent; Adult; Age Factors; Aged; Apolipoproteins; Captopril; Cholesterol; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Sex Factors; Single-Blind Method; Time Factors | 1993 |
[Efficacy and tolerability of the captopril and hydrochlorothiazide combination in the treatment of mild to moderate hypertension. Multicenter study].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index | 1995 |
Combined treatment with captopril, hydrochlorothiazide and pravastatin in dyslipidemic hypertensive patients.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Antihypertensive Agents; Captopril; Combined Modality Therapy; Diuretics; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Male; Middle Aged; Pravastatin; Prospective Studies; Sodium Chloride Symporter Inhibitors | 1995 |
Effects of hydrochlorothiazide and captopril on lipoprotein lipid composition in patients with essential hypertension.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Single-Blind Method; Triglycerides | 1996 |
Arterial stiffness, hydrochlorothiazide and converting enzyme inhibition in essential hypertension.
Topics: Adult; Aged; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Treatment Outcome | 1996 |
An equivalence study of the safety and efficacy of a fixed-dose combination of perindopril with indapamide versus fixed-dose combinations of captopril with hydrochlorothiazide and enalapril with hydrochlorothiazide in the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Captopril; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Indoles; Male; Middle Aged; Perindopril; Potassium; Retrospective Studies; Therapeutic Equivalency | 1995 |
The effects of replacing beta-blockers with an angiotensin converting enzyme inhibitor on the quality of life of hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Pressure; Captopril; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol; Quality of Life; Sodium Chloride Symporter Inhibitors; Surveys and Questionnaires | 1996 |
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Clonidine; Cohort Studies; Diltiazem; Diuretics; Double-Blind Method; Echocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Organ Size; Prazosin; Prevalence; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States; United States Department of Veterans Affairs | 1997 |
The effects of antihypertensive combination therapy on lipid and glucose metabolism: hydrochlorothiazide plus sotalol vs. hydrochlorothiazide plus captopril.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Captopril; Diuretics; Drug Therapy, Combination; Hemoglobin A; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Radioimmunoassay; Sodium Chloride Symporter Inhibitors; Sotalol | 1997 |
[The Multicenter Captopril and the Quality of Life Study: the effect of antihypertensive agents from the basic groups on the quality of life of patients in different populations. The working group of the Multicenter Captopril and the Quality of Life Study
Topics: Antihypertensive Agents; Azerbaijan; Captopril; Demography; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Moscow; Nifedipine; Propranolol; Quality of Life; Russia; Ukraine; Urban Population | 1996 |
Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension. Systolic Hypertension in China (Syst-China) Collaborative Group.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Cerebrovascular Disorders; China; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine; Placebo Effect; Sodium Chloride Symporter Inhibitors; Systole | 1998 |
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Clonidine; Diltiazem; Diuretics; Double-Blind Method; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Potassium; Prazosin; Time Factors; Treatment Outcome; United States | 1999 |
Combination therapy with felodipine and metoprolol compared with captopril and hydrochlorothiazide. German MC Study Group.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged | 1998 |
[Captopril combined with hydrochlorothiazide in mild and moderate hypertension. A Brazilian multicenter study].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Captopril; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors | 1998 |
[Antihypertensive efficacy, tolerance and safety of lisinopril (sinopril) and captopril (capoten) in patients with mild and moderate arterial hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diuretics; Drug Hypersensitivity; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Safety; Severity of Illness Index; Sodium Chloride Symporter Inhibitors; Treatment Outcome | 1999 |
Chinese trial on isolated systolic hypertension in the elderly. Systolic Hypertension in China (Syst-China) Collaborative Group.
Topics: Aged; Alcohol Drinking; Antihypertensive Agents; Asian People; Blood Pressure; Captopril; Cardiovascular Diseases; China; Diabetes Complications; Female; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Nitrendipine; Prospective Studies; Risk Factors; Sex Factors; Smoking | 2000 |
Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Confidence Intervals; Cross-Over Studies; Delayed-Action Preparations; Drug Combinations; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Lipoproteins; Male; Middle Aged; Treatment Outcome; Vasodilator Agents; Verapamil | 2000 |
[Capozide-50 alone and in combination with melatonin in therapy of hypertension].
Topics: Antioxidants; Blood Pressure; Captopril; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Melatonin; Middle Aged; Prognosis | 2000 |
Prognostic significance of serum creatinine and uric acid in older Chinese patients with isolated systolic hypertension.
Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Cardiovascular Diseases; China; Creatinine; Diuretics; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nitrendipine; Prognosis; Regression Analysis; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Uric Acid | 2001 |
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Diltiazem; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pressure; Pulse; Randomized Controlled Trials as Topic; Systole; Time Factors; Treatment Outcome | 2001 |
Comparison of benazepril-amlodipine and captopril-thiazide combinations in the management of mild-to-moderate hypertension.
Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Captopril; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 2002 |
Evaluation of the efficacy and tolerability of the combination delapril plus indapamide in the treatment of mild to moderate essential hypertension: a randomised, multicentre, controlled study.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Indans; Indapamide; Male; Middle Aged; Severity of Illness Index | 2003 |
Antihypertensive treatment and homocysteine concentrations.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cardiovascular Diseases; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Homocysteine; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
[Comparison of noliprel and caposide efficacy in patients with arterial hypertension of high risk].
Topics: Antihypertensive Agents; Captopril; Cardiomegaly; Female; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Male; Middle Aged; Perindopril; Treatment Outcome | 2005 |
[Comparative efficacy of fixed dose combinations of enalapril with hydrochlorothiazide and captopril with hydrochlorothiazide in patients with high risk hypertension].
Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cost-Benefit Analysis; Diuretics; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Time Factors; Treatment Outcome | 2005 |
[Comparative efficacy of fixed dose combinations of perindopril with indapamide and captopril with hydrochlorothiazide in patients with high risk hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Male; Middle Aged; Perindopril; Risk Factors | 2005 |
Simultaneous determination of captopril and hydrochlorothiazide in human plasma by reverse-phase HPLC from linear gradient elution.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Male; Reproducibility of Results; Sodium Chloride Symporter Inhibitors; Spectrophotometry, Ultraviolet; Tablets; Technology, Pharmaceutical | 2006 |
Urinary TGF-beta1 reduction related to a decrease of systolic blood pressure in patients with type 2 diabetes and clinical diabetic nephropathy.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Captopril; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propranolol; Ramipril; Transforming Growth Factor beta1 | 2006 |
Sex differences in blood pressure response to antihypertensive therapy in Chinese patients with hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Asian People; Atenolol; Blood Pressure; Captopril; China; Delayed-Action Preparations; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Sex Factors | 2008 |
[Impact of patient compliance on the outcomes in hypertensive patients receiving hydrochlorothiazide based combination therapy with spironolactone or captopril].
Topics: Aged; Antihypertensive Agents; Captopril; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Spironolactone; Treatment Outcome | 2008 |
Zofenopril plus hydrochlorothiazide and irbesartan plus hydrochlorothiazide in previously treated and uncontrolled diabetic and non-diabetic essential hypertensive patients.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Captopril; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Young Adult | 2014 |
Zofenopril or irbesartan plus hydrochlorothiazide in elderly patients with isolated systolic hypertension untreated or uncontrolled by previous treatment: a double-blind, randomized study.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Systole; Tetrazoles; Treatment Outcome; Vascular Stiffness | 2016 |
Fixed-dose combination of zofenopril plus hydrochlorothiazide vs. irbesartan plus hydrochlorothiazide in hypertensive patients with established metabolic syndrome uncontrolled by previous monotherapy. The ZAMES study (Zofenopril in Advanced MEtabolic Synd
Topics: Aged; Biphenyl Compounds; Captopril; Female; Humans; Hydrochlorothiazide; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Tetrazoles | 2016 |
Influence of Hypersensitive C-Reactive Protein on the Effect of Continuous Antihypertensive Pharmacological Therapy.
Topics: Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Captopril; Humans; Hydrochlorothiazide; Hypertension; Nitrendipine; Spironolactone | 2022 |
147 other study(ies) available for captopril and hydrochlorothiazide
| Article | Year |
|---|---|
Angiotensin-converting enzyme inhibitors. 9. Novel [[N-(1-carboxy-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diuretics; Drug Design; Glycine; Male; Propylamines; Rats; Rats, Inbred SHR | 1990 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
[The dynamics of the concentration of atrial natriuretic factor depending on changes in the arterial pressure level in patients with arterial hypertension].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Captopril; Chronic Disease; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nifedipine; Propranolol; Renin | 1992 |
Chronic antihypertensive treatment with captopril plus hydrochlorothiazide improves aortic distensibility in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Body Weight; Captopril; Decerebrate State; Eating; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
[Efficacy and tolerability of a preconstituted combination of captopril 50 mg + hydrochlorothiazide 25 mg in aged subjects with isolated systolic hypertension].
Topics: Aged; Aged, 80 and over; Captopril; Drug Combinations; Drug Tolerance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1992 |
Renal functional response to captopril during diuretic therapy.
Topics: Animals; Captopril; Chlorothiazide; Furosemide; Hydrochlorothiazide; Hypertension, Renovascular; Iodine Radioisotopes; Iodohippuric Acid; Kidney; Kidney Function Tests; Male; Radioisotope Renography; Rats; Rats, Inbred Strains; Technetium Tc 99m Pentetate | 1992 |
Effects of a new dihydropyridine derivative, FRC-8653, on blood pressure in conscious spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Dihydropyridines; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR | 1992 |
Chronopharmacology of captopril plus hydrochlorothiazide in hypertension: morning versus evening dosing.
Topics: Blood Pressure; Captopril; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1991 |
[Collateral effects induced by therapy with diuretics (clinical case of ventricular fibrillation caused by hypokalemia].
Topics: Aged; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypokalemia; Male; Ventricular Fibrillation | 1991 |
Ambulatory blood pressure monitoring for the evaluation of once-daily ACE inhibition: a comparison study of captopril and enalapril combined with hydrochlorothiazide.
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Monitoring, Physiologic | 1991 |
Effects of antihypertensive drugs on heart and resistance vessels.
Topics: Animals; Blood Pressure; Body Weight; Captopril; Heart; Hindlimb; Hydrochlorothiazide; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance | 1990 |
Effect of diuretics on captopril-induced urinary zinc excretion.
Topics: Adult; Captopril; Creatinine; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Zinc | 1990 |
Longterm effects of captopril and hydrochlorothiazide on glucose metabolism in the hypertensive patient.
Topics: Blood Glucose; Captopril; Humans; Hydrochlorothiazide; Hypertension; Insulin; Lipids | 1990 |
[Report on treatment with captopril and hydrochlorothiazide combination. Comprehensive therapy of hypertension].
Topics: Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension | 1990 |
Metabolic effects of the combination of captopril and hydrochlorothiazide in hypertensive subjects.
Topics: Adult; Aged; Blood Pressure; Captopril; Diastole; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins; Male; Middle Aged; Systole | 1990 |
The effects of hydrochlorothiazide and captopril on glucose and lipid metabolism.
Topics: Captopril; Glucose; Humans; Hydrochlorothiazide; Lipid Metabolism; Stimulation, Chemical | 1990 |
Captopril and hydrochlorothiazide combined: Acezide/Capozide.
Topics: Captopril; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Male | 1989 |
Role of lowering arterial pressure on maximal coronary flow with and without regression of cardiac hypertrophy.
Topics: Animals; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Coronary Circulation; Heart; Hydralazine; Hydrochlorothiazide; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Systole; Time Factors | 1989 |
Renal vascular effects of antihypertensive therapy in uninephrectomized SHR.
Topics: Animals; Antihypertensive Agents; Captopril; Enalapril; Hydralazine; Hydrochlorothiazide; Hypertension, Renovascular; Kidney; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Renal Circulation; Reserpine | 1989 |
Effect of chronic nifedipine in patients inadequately controlled by a converting enzyme inhibitor and a diuretic.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Dipeptides; Drug Resistance; Enalapril; Female; Furosemide; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Potassium; Substance Withdrawal Syndrome | 1985 |
[Effect of captopril therapy on sodium and water excretion in patients with liver cirrhosis and ascites].
Topics: Adult; Aged; Ascites; Blood Pressure; Captopril; Diuresis; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Furosemide; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Liver Cirrhosis; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Spironolactone; Water-Electrolyte Balance | 1989 |
Assessing duration of antihypertensive effects with whole-day blood pressure monitoring.
Topics: Aged; Blood Pressure; Blood Pressure Determination; Captopril; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monitoring, Physiologic | 1989 |
Short and long term effects of antihypertensive therapy in the diabetic rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Administration Schedule; Drug Therapy, Combination; Glomerular Filtration Rate; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Reserpine; Time Factors | 1989 |
[Captopril and hydrochlorothiazide combined in the treatment of mild-to-moderate hypertension. Evaluation of sugar and lipid metabolism in a long-term study].
Topics: Adult; Aged; Blood Glucose; Captopril; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Time Factors | 1989 |
[Value of combination therapy with Tensobon].
Topics: Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Proline | 1985 |
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Diuretics; Electrolytes; Hydrochlorothiazide; Hypertension; Hypertrophy; Indapamide; Kidney; Male; Prazosin; Pyridines; Rats; Rats, Inbred SHR | 1988 |
Synthesis and pharmacology of the potent angiotensin-converting enzyme inhibitor N-[1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl-(S)-pyroglutamic acid.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Chemical Phenomena; Chemistry; Diet, Sodium-Restricted; Dipeptides; Enalapril; Heart Rate; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Inbred SHR | 1985 |
[Diuretic-resistant hypertension. Effect of an additional daily single dose of a ACE inhibitor].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cholinesterase Inhibitors; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A | 1985 |
Renal insufficiency during angiotensin-converting enzyme inhibitor therapy in hypertensive patients with no renal artery stenosis.
Topics: Acute Kidney Injury; Captopril; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Kidney Diseases; Male; Middle Aged; Oligopeptides; Teprotide | 1985 |
Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Enalapril; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Potassium | 1986 |
[Chronobiological study of the antihypertensive effect of captopril-hydrochlorothiazide combination administered in a single low dose].
Topics: Adult; Aged; Captopril; Circadian Rhythm; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1988 |
[The effectiveness and duration of antihypertensive action of captopril 50 mg. + hydrochlorothiazide 25 mg. (CAP + HCTZ)].
Topics: Adult; Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Time Factors | 1988 |
[Combination captopril-hydrochlorothiazide in a single dose for treatment of essential arterial hypertension].
Topics: Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1988 |
Age and antihypertensive drugs (hydrochlorothiazide, bendroflumethiazide, nadolol and captopril).
Topics: Adult; Aged; Aging; Bendroflumethiazide; Black People; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Random Allocation; White People | 1988 |
Glucose metabolism during captopril mono- and combination therapy in diabetic hypertensive patients: a multiclinic trial.
Topics: Blood Glucose; Captopril; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension | 1987 |
[Treatment of essential arterial hypertension in the elderly with low-dose captopril and hydrochlorothiazide. Long-term study].
Topics: Aged; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Retrospective Studies | 1987 |
[Preliminary evaluation of the therapeutic efficacy of a combination of captopril 50 mg + hydrochlorothiazide 25 mg (Aceplus 50/25)].
Topics: Adult; Captopril; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Male | 1987 |
Low-dose captopril alone and in combination with hydrochlorothiazide in the treatment of mild to moderate essential hypertension.
Topics: Adult; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1986 |
Efficacy of low dose captopril once daily in diuretic resistant hypertension.
Topics: Adult; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Time Factors | 1986 |
Effect of converting enzyme inhibitors in hypertensive patients with non-insulin-dependent diabetes mellitus.
Topics: Blood Glucose; Blood Pressure; Captopril; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1986 |
Serum potassium concentrations after initiation of captopril therapy.
Topics: Aged; Antihypertensive Agents; Captopril; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Potassium; Retrospective Studies; Triamterene | 1986 |
[Validity and effectiveness of a pre-constituted captopril-hydrochlorothiazide combination in a single daily dose].
Topics: Adult; Aged; Captopril; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1986 |
Differential structural responses of small resistance vessels to antihypertensive therapy.
Topics: Animals; Antihypertensive Agents; Blood Vessels; Captopril; Hindlimb; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Vascular Resistance | 1987 |
Effect of captopril and hydrochlorothiazide on glomerular haemodynamics and histological damage in Goldblatt hypertension with partial renal ablation.
Topics: Animals; Captopril; Hemodynamics; Hydrochlorothiazide; Hypertension, Renovascular; Kidney Glomerulus; Male; Nephrectomy; Rats | 1986 |
Captopril + hydrochlorothiazide 24 h ambulatory monitoring effects.
Topics: Adult; Aged; Ambulatory Care; Blood Pressure; Captopril; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monitoring, Physiologic | 1987 |
[Clinical and diagnostic evaluation of the treatment of systemic arterial hypertension with captopril and hydrochlorothiazide].
Topics: Adult; Captopril; Drug Evaluation; Drug Therapy, Combination; Echocardiography; Electrocardiography; Exercise Test; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Phonocardiography; Proline | 1985 |
Essential hypertension: a metabolic cause? A hypothesis.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Calcium; Captopril; Female; Humans; Hydrochlorothiazide; Hypertension; Lactates; Lactic Acid; Male; Middle Aged; Potassium; Potassium Chloride; Propranolol; Renin; Spironolactone | 1985 |
[Ergometric evaluation of effects of captopril in hypertensive patients with exertion-induced angina].
Topics: Aged; Angina Pectoris; Captopril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1985 |
Comparison of low-dose captopril and propranolol as second-line drugs in mild and moderate hypertension.
Topics: Adult; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol | 1985 |
Therapeutic rounds.
Topics: Captopril; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension, Renovascular; Middle Aged | 1985 |
Converting enzyme activity in regulation of blood pressure and kidney function. A review.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Kidney Function Tests; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Water-Electrolyte Balance | 1984 |
Biochemical monitoring of vasoactive peptides during angiotensin converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cross Reactions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Peptidyl-Dipeptidase A; Radioimmunoassay; Renin | 1983 |
[Interaction between antihypertensive and antirheumatic agents].
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Aprotinin; Captopril; Dogs; Drug Antagonism; Drug Interactions; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Indomethacin; Propranolol; Prostaglandins; Rabbits; Renin-Angiotensin System | 1983 |
Acute antihypertensive synergism of angiotensin-converting enzyme inhibitors and diuretics.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Captopril; Dipeptides; Drug Synergism; Drug Therapy, Combination; Enalapril; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Indomethacin; Proline; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System | 1984 |
Hormonal responses to angiotensin blockade. Comparison between receptor antagonism and converting enzyme inhibition.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin | 1980 |
Inhibitors of angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Blood Pressure; Bradykinin; Captopril; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Protease Inhibitors; Rabbits; Rats; Snake Venoms; Structure-Activity Relationship | 1980 |
Endocrine profile in the long-term phase of converting-enzyme inhibition.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diet, Sodium-Restricted; Female; Humans; Hydrochlorothiazide; Hypertension; Kinins; Male; Middle Aged; Proline; Prostaglandins; Renin | 1980 |
Efficacy of an oral angiotensin-converting enzyme inhibitor (captopril) in severe hypertension.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol | 1981 |
Acute and chronic effects of the angiotensin-converting enzyme inhibitor captopril in severe hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Middle Aged; Potassium; Proline; Renin | 1982 |
Studies on the mechanism of the enhancement of the antihypertensive activity of captopril by a diuretic in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Drug Synergism; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains; Renin; Serotonin; Vascular Resistance | 1982 |
Effect of antihypertensive therapy on sympathetic nervous system activity in patients with essential hypertension.
Topics: Antihypertensive Agents; Captopril; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reserpine; Sympathetic Nervous System; Vasodilator Agents | 1984 |
Captopril in mild and moderate essential hypertension: physiological and biochemical monitoring.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Plasma Volume; Proline; Renin-Angiotensin System; Time Factors | 1983 |
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains | 1983 |
Low-dose captopril titration in patients with moderate-to-severe hypertension treated with diuretics.
Topics: Adult; Aged; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Furosemide; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Proline; Time Factors | 1983 |
Analysis of captopril and hydrochlorothiazide combination tablet formulations by liquid chromatography.
Topics: Captopril; Chromatography, High Pressure Liquid; Drug Combinations; Hydrochlorothiazide; Oxidation-Reduction; Proline; Tablets | 1984 |
[Antihypertensive effect of captopril in patients with mild or moderate systemic arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1984 |
Time course of antihypertensive effect of low-dose captopril in mild to moderate hypertension.
Topics: Administration, Oral; Blood Pressure; Captopril; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Proline; Time Factors | 1984 |
Mechanism for the high bias in the USP colorimetric assay for diazotizable substances in hydrochlorothiazide.
Topics: Amines; Captopril; Chromatography, High Pressure Liquid; Colorimetry; Hydrochlorothiazide; Kinetics; Nitroso Compounds; Powders | 1984 |
Combined captopril and hydrochlorothiazide therapy in severe hypertension: long-term haemodynamic changes at rest and during exercise.
Topics: Adult; Aged; Blood Glucose; Body Weight; Captopril; Cardiac Output; Creatinine; Diastole; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxygen Consumption; Physical Exertion; Proline; Rest; Stroke Volume; Systole; Time Factors; Vascular Resistance | 1984 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Relationship, Drug; Hydrochlorothiazide; Hypertension; Male; Nicardipine; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents | 1980 |
Captopril in essential hypertension.
Topics: Adult; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Renin | 1982 |
Long-term experience of captopril in the treatment of primary (essential) hypertension.
Topics: Adult; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline | 1982 |
[Effect of captopril on blood pressure in various types of hypertensive rats].
Topics: Animals; Blood Pressure; Captopril; Female; Hydrochlorothiazide; Hypertension; Male; Proline; Rats | 1982 |
Hemodynamic effects of captopril in essential hypertension, renovascular hypertension and cardiac failure: correlations with short- and long-term effects on plasma renin.
Topics: Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Long-Term Care; Male; Middle Aged; Proline; Renal Artery Obstruction; Renin; Water-Electrolyte Balance | 1982 |
Captopril in severe treatment-resistant hypertension.
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Female; Furosemide; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Myocardial Infarction; Proline; Propranolol; Renin | 1980 |
[Captopril in the clinical treatment of renovascular hypertension].
Topics: Adult; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension, Renal; Hypertension, Renovascular; Male; Proline; Propranolol | 1980 |
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Hydrochlorothiazide; Hypertension; Indomethacin; Male; Methyltyrosines; Prazosin; Propranolol; Quinazolines; Rats; Renin | 1981 |
Captopril combined with thiazide lowers renin substrate concentration: implications for methodology in renin assays.
Topics: Angiotensinogen; Angiotensins; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Methods; Proline; Propranolol; Renin | 1981 |
[Treatment of "therapy-resistant" forms of hypertension with captopril].
Topics: Ambulatory Care; Antihypertensive Agents; Captopril; Diuretics; Drug Resistance; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Proline; Renal Dialysis | 1981 |
[Captopril in treatment-resistant hypertension (author's transl)].
Topics: Adult; Captopril; Diastole; Drug Combinations; Female; Furosemide; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Proline; Propranolol; Pulse; Systole; Time Factors | 1980 |
[Effect of captopril in essential hypertension (author's transl)].
Topics: Adult; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Renin | 1981 |
Captopril, alone and in combination with hydrochlorothiazide, on responses to upright tilt in conscious dogs.
Topics: Animals; Blood Pressure; Captopril; Dogs; Female; Heart Rate; Hydrochlorothiazide; Male; Posture; Proline; Renin; Time Factors | 1981 |
Comparison of the effects of captopril, diuretic and their combination in low- and normal-renin essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Proline; Renin; Renin-Angiotensin System | 1982 |
Captopril in the treatment of moderate to severe hypertension. A long-term study.
Topics: Adult; Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Renin; Time Factors | 1981 |
Clinical use of captopril. Illustrative cases.
Topics: Adult; Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Proline | 1982 |
Role of sympathetic nervous system activity in the blood pressure response to long-term captopril therapy in severely hypertensive patients.
Topics: Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Norepinephrine; Potassium; Proline; Propranolol; Renin; Sympathetic Nervous System | 1982 |
Studies on the mechanism of the synergistic antihypertensive activity of captopril and hydrochlorothiazide following acute administration in spontaneously hypertensive rats.
Topics: Animals; Captopril; Drug Synergism; Drug Therapy, Combination; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Proline; Rats; Rats, Inbred Strains; Renin | 1982 |
Alterations of methionine fluxes and incorporation in intestines of miniature pigs fed a diet high in caseinate are restricted by angiotensin-converting enzyme inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Caseins; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Epithelium; Homocysteine; Hydrochlorothiazide; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methionine; Random Allocation; Sodium Chloride Symporter Inhibitors; Swine; Swine, Miniature; Tritium | 1995 |
Normal left ventricular diastolic compliance after regression of hypertrophy.
Topics: Aging; Animals; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Collagen; Diastole; Elasticity; Hydrochlorothiazide; Hydroxyproline; In Vitro Techniques; Male; Rats; Rats, Inbred F344; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Ventricular Function, Left | 1994 |
Hyperhomocysteinemia-induced vascular damage in the minipig. Captopril-hydrochlorothiazide combination prevents elastic alterations.
Topics: Animals; Blood Vessels; Captopril; Caseins; Diet; Drug Combinations; Hemorheology; Hindlimb; Homocysteine; Hydrochlorothiazide; Hypertension; Male; Methionine; Swine; Swine, Miniature; Vascular Diseases | 1995 |
Combination products as first-line pharmacotherapy.
Topics: Captopril; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension | 1995 |
What's your assessment? Photoallergy reaction.
Topics: Captopril; Diagnosis, Differential; Drug Hypersensitivity; Humans; Hydrochlorothiazide; Male; Middle Aged; Nursing Assessment; Photosensitivity Disorders | 1994 |
[Comparative analysis of several treatment methods for severe congestive heart failure].
Topics: Adult; Aged; Aged, 80 and over; Captopril; Digoxin; Drugs, Chinese Herbal; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Nifedipine | 1993 |
[A preliminary study of insulin resistance in essential hypertension, simple obesity and acromegaly].
Topics: Acromegaly; Adult; Blood Glucose; Captopril; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged; Obesity | 1993 |
Effects of hydrochlorothiazide and captopril on the survival and heart weight of cardiomyopathic hamsters.
Topics: Animals; Captopril; Cardiomyopathies; Cricetinae; Drug Therapy, Combination; Hydrochlorothiazide; Male; Myocardium; Organ Size | 1993 |
[Treatment of mild hypertension with captopril and captopril with hydrochlorothiazide. Impact on blood pressure values and quality of life].
Topics: Adult; Aged; Blood Pressure; Captopril; Clinical Protocols; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nutritional Status; Quality of Life | 1993 |
Captopril and hydrochlorothiazide (Capozide) combine to enhance the reduction in voluntary alcohol intake in rats.
Topics: Alcohol Drinking; Animals; Captopril; Dose-Response Relationship, Drug; Drinking; Drug Combinations; Drug Therapy, Combination; Ethanol; Hydrochlorothiazide; Male; Rats; Rats, Wistar; Renin-Angiotensin System | 1993 |
[Captopril and hydrochlorothiazide. Advantages of their synergistic effect].
Topics: Captopril; Drug Synergism; Drug Therapy, Combination; Humans; Hydrochlorothiazide | 1993 |
[The clinical efficacy of Korinfar-retard in combination with Cordanum, triampur and Capoten in patients with arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Captopril; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Propanolamines; Time Factors; Triamterene | 1996 |
[Relevance of general practitioner's prescriptions for hospital pharmacotherapy. A survey of hospital physicians].
Topics: Aged; Attitude of Health Personnel; Captopril; Data Interpretation, Statistical; Diabetes Mellitus; Drug Combinations; Drug Prescriptions; Drug Therapy; Family Practice; Female; Flavonoids; Ginkgo biloba; Hemostatics; Humans; Hydrochlorothiazide; Hypertension; Male; Medical Staff, Hospital; Middle Aged; Plant Extracts; Prostatic Hyperplasia; Sitosterols; Surveys and Questionnaires | 1996 |
Effects of antihypertensive drugs or glycemic control on antioxidant enzyme activities in spontaneously hypertensive rats with diabetes.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Captopril; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Glutathione Peroxidase; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reserpine; Superoxide Dismutase | 1997 |
Studies on pyrazinoylguanidine. 5. Temporal effects over 24 weeks demonstrating attenuation of diabetic nephropathy in STZ-diabetic rats.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Guanidines; Hydrochlorothiazide; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Kidney; Kidney Function Tests; Male; Molecular Weight; Pyrazines; Rats; Rats, Sprague-Dawley; Serum Albumin; Streptozocin | 1997 |
Effects of antihypertensive drugs on antioxidant enzyme activities and renal function in stroke-prone spontaneously hypertensive rats.
Topics: Acetylglucosaminidase; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Catalase; Drug Therapy, Combination; Glutathione Peroxidase; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Function Tests; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; Reserpine; Superoxide Dismutase | 1997 |
Hyperhomocysteinemia induces elastolysis in minipig arteries: structural consequences, arterial site specificity and effect of captopril-hydrochlorothiazide.
Topics: Animals; Antihypertensive Agents; Aorta, Abdominal; Captopril; Coronary Vessels; Disease Models, Animal; Elastic Tissue; Elasticity; Elastin; Hydrochlorothiazide; Hyperhomocysteinemia; Swine; Swine, Miniature | 1998 |
Effects of aging and antihypertensive treatment on aortic internal diameter in spontaneously hypertensive rats.
Topics: Age Factors; Aging; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Diuretics; Hydrochlorothiazide; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride Symporter Inhibitors; Time Factors | 1999 |
Antihypertensive therapy in renal patients - benefits and difficulties.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Diuretics; Doxazosin; Humans; Hydrochlorothiazide; Hypertension, Renal; Kidney Failure, Chronic; Kidney Glomerulus; Male; Nitrendipine; Proteinuria; Renal Circulation; Triamterene | 1999 |
[Effective treatment of cardiac failure with caposide at an outpatient clinic].
Topics: Aged; Ambulatory Care; Captopril; Cardiac Output, Low; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Middle Aged | 2001 |
Perindopril + indapamide: new preparation. Simple trick.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Perindopril; Treatment Outcome | 1999 |
Simultaneous resolution of a binary mixture of captopril and hydrochlorothiazide in tablets by bivariate and multivariate spectral calibrations.
Topics: Algorithms; Antihypertensive Agents; Calibration; Captopril; Drug Combinations; Hydrochlorothiazide; Pharmaceutical Solutions; Regression Analysis; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets | 2003 |
Automated simultaneous triple dissolution profiles of two drugs, sulphamethoxazole-trimethoprim and hydrochlorothiazide-captopril in solid oral dosage forms by a multicommutation flow-assembly and derivative spectrophotometry.
Topics: Administration, Oral; Captopril; Dosage Forms; Hydrochlorothiazide; Solubility; Spectrophotometry, Ultraviolet; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |
Effects of angiotensin-converting-enzyme inhibitors in combination with diuretics on blood pressure and renal injury in nitric oxide-deficiency-induced hypertension in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Diuretics; Drug Therapy, Combination; Enalapril; Hydrochlorothiazide; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2006 |
Hydrochlorothiazide increases plasma or tissue angiotensin-converting enzyme-inhibitor drug levels in rats with myocardial infarction: differential effects on lisinopril and zofenopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Creatinine; Drug Therapy, Combination; Heart Ventricles; Hydrochlorothiazide; Hypertrophy, Left Ventricular; Kidney; Kidney Function Tests; Lisinopril; Male; Myocardial Infarction; Peptidyl-Dipeptidase A; Prodrugs; Rats; Rats, Sprague-Dawley; Ventricular Function | 2005 |
Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Drug Therapy, Combination; Erythropoietin; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Losartan; Nephrectomy; Rats; Rats, Wistar; Recombinant Proteins; Renin-Angiotensin System; Reserpine; Time Factors; Uremia | 2006 |
Chronic and acute effects of different antihypertensive drugs on femoral artery relaxation of L-NAME hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Diuretics; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Femoral Artery; Heart Ventricles; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2007 |
Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Captopril; Hydrochlorothiazide; Losartan; Mice; Nifedipine; RNA, Messenger; Telmisartan | 2009 |
HPLC-DAD method for the simultaneous determination of zofenopril and hydrochlorothiazide in oral pharmaceutical formulations.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calibration; Captopril; Chromatography, High Pressure Liquid; Diuretics; Hydrochlorothiazide; Limit of Detection; Pharmaceutical Preparations; Reference Standards; Reproducibility of Results | 2010 |
Availability, price and affordability of cardiovascular medicines: a comparison across 36 countries using WHO/HAI data.
Topics: Antihypertensive Agents; Atenolol; Captopril; Cardiovascular Diseases; Cost of Illness; Developing Countries; Health Services Accessibility; Humans; Hydrochlorothiazide; Losartan; Nifedipine; World Health Organization | 2010 |
Anti-inflammatory effects of anti-hypertensive agents: influence on interleukin-1β secretion by peripheral blood polymorphonuclear leukocytes from patients with essential hypertension.
Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Atenolol; Captopril; Case-Control Studies; Female; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Losartan; Male; Middle Aged; Neutrophils | 2011 |
Role of blood pressure and the renin-angiotensin system in development of diabetic nephropathy (DN) in eNOS-/- db/db mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hydralazine; Hydrochlorothiazide; Mice; Mice, Knockout; Nitric Oxide Synthase Type III; Renin-Angiotensin System; Reserpine | 2012 |
Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats.
Topics: Acute Kidney Injury; Animals; Antibodies, Anti-Idiotypic; Antihypertensive Agents; Blood Pressure; Captopril; Diltiazem; Disease Models, Animal; Female; Fibrosis; Hydrochlorothiazide; Hypertension; Male; Proteinuria; Rats; Rats, Inbred Dahl; Sex Characteristics; Sodium Chloride, Dietary; Transforming Growth Factor beta | 2012 |
[Study on the proficiency testing program of pharmaceutical preparation analysis].
Topics: Accreditation; Captopril; Drug Combinations; Drug Stability; Hydrochlorothiazide; Laboratory Proficiency Testing; Pharmaceutical Preparations | 2012 |
Simultaneous estimation and validation of some binary mixtures of antihypertensive drugs by RP-LC methods using two new generation silica columns.
Topics: Antihypertensive Agents; Captopril; Chromatography, Reverse-Phase; Hydrochlorothiazide; Imidazoles; Indicators and Reagents; Silicon Dioxide; Solvents; Tetrazoles | 2013 |
Application of capillary electrophoresis-frontal analysis for comparative evaluation of the binding interaction of captopril with human serum albumin in the absence and presence of hydrochlorothiazide.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Binding, Competitive; Captopril; Drug Combinations; Electrophoresis, Capillary; Humans; Hydrochlorothiazide; Models, Chemical; Protein Binding; Serum Albumin | 2015 |
Cyclodextrin- and solvent-modified micellar electrokinetic chromatography for the determination of captopril, hydrochlorothiazide and their impurities: A Quality by Design approach.
Topics: 1-Butanol; Captopril; Chromatography, Micellar Electrokinetic Capillary; Drug Combinations; Drug Contamination; Electrophoresis, Capillary; gamma-Cyclodextrins; Hydrochlorothiazide; Micelles; Solvents; Tablets | 2016 |
Amplified nanostructure electrochemical sensor for simultaneous determination of captopril, acetaminophen, tyrosine and hydrochlorothiazide.
Topics: Acetaminophen; Captopril; Electrochemical Techniques; Humans; Hydrochlorothiazide; Nanostructures; Nanotubes, Carbon; Nickel; Oxidation-Reduction; Tyrosine; X-Ray Diffraction | 2017 |
A Validated High-Performance Thin-Layer Chromatographic Method for the Simultaneous Determination of Zofenopril Calcium and Hydrochlorothiazide in the Presence of the Hydrochlorothiazide Impurities: Chlorothiazide and Salamide.
Topics: Calibration; Captopril; Chlorothiazide; Chromatography, Thin Layer; Drug Combinations; Drug Contamination; Hydrochlorothiazide; Limit of Detection; Sulfonamides; Tablets | 2018 |
A Capillary Zone Electrophoresis Method with Multiresponse Chemometric Optimization for the Simultaneous Determination of Zofenopril Calcium and Hydrochlorothiazide in Presence of Hydrochlorothiazide Major Impurities.
Topics: Captopril; Drug Combinations; Drug Contamination; Electrophoresis, Capillary; Hydrochlorothiazide; Limit of Detection; Linear Models; Reproducibility of Results | 2018 |
Cytotoxic and genotoxic effects of antihypertensives distributed in Brazil by social programs: Are they safe?
Topics: Antihypertensive Agents; Atenolol; Brazil; Captopril; Cell Survival; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Enalapril; Government Programs; Humans; Hydrochlorothiazide; Hypertension; Losartan; Lymphocytes; Macrophages; Male; Mutagenicity Tests; Program Evaluation; Propranolol | 2018 |
Simultaneous ultraperformance liquid chromatography/tandem mass spectrometry determination of four antihypertensive drugs in human plasma using hydrophilic-lipophilic balanced reversed-phase sorbents sample preparation protocol.
Topics: Antihypertensive Agents; Benzazepines; Captopril; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Fosinopril; Humans; Hydrochlorothiazide; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Linear Models; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2018 |
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan | 2019 |
Captopril Combined with Furosemide or Hydrochlorothiazide Affects Macrophage Functions in Mouse Contact Hypersensitivity Response.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dermatitis, Contact; Diuretics; Drug Therapy, Combination; Furosemide; Hydrochlorothiazide; Hypertension; Macrophages; Male; Mice; Mice, Inbred CBA; Nitric Oxide | 2021 |
[Preparation and
Topics: Captopril; Cytidine Triphosphate; Drug Liberation; Hydrochlorothiazide; Printing, Three-Dimensional; Tablets; Technology, Pharmaceutical | 2022 |