Page last updated: 2024-08-23

captopril and felodipine

captopril has been researched along with felodipine in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.57)	18.7374
1990's	7 (25.00)	18.2507
2000's	9 (32.14)	29.6817
2010's	11 (39.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Abrego, VH; Amaro-Recillas, HA; Angeles, E; Marroquín-Pascual, JL; Martínez, L; Martínez-Pérez, B; Moya-Hernández, R; Rodríguez-Barrientos, D; Rojas-Hernández, A; Rueda-Jackson, JC; Torres, LA	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Muir, AL; Nolan, J	1
Littler, WA; Smith, SA	1
Conway, EL; Howes, LG; Krum, H; Lam, W; Louis, WJ; O'Callaghan, CJ; Skiba, MA	1
Janssen, BJ; Oosting, J; Struyker-Boudier, HA; Tyssen, CM	1
Boudier, HA; Daemen, MJ; Nelissen-Vrancken, HJ; Smits, JF	1
Boissel, JP; Gueyffier, F	1
Ostergren, J	1
Klein, G	1
Abd El-Fattah, AA; El-Sayed, MI; Zuhair, HA	1
Bai, S; Chen, L; Ding, BP; Huang, ZG; Wang, JT	1

Reviews

2 review(s) available for captopril and felodipine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antihypertensive agents--the race for third place. Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2 Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil	1985

Trials

2 trial(s) available for captopril and felodipine

Article	Year
Short term effects of pravastatin on blood pressure in hypercholesterolaemic hypertensive patients. Blood pressure, 1994, Volume: 3, Issue:6 Topics: Blood Pressure; Captopril; Cholesterol; Cholesterol, LDL; Combined Modality Therapy; Double-Blind Method; Drug Interactions; Felodipine; Female; Humans; Hypercholesterolemia; Hypertension; Lipids; Male; Middle Aged; Pravastatin	1994
Combination therapy with felodipine and metoprolol compared with captopril and hydrochlorothiazide. German MC Study Group. Blood pressure, 1998, Volume: 7, Issue:5-6 Topics: Antihypertensive Agents; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged	1998

Other Studies

24 other study(ies) available for captopril and felodipine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Antihypertensive and antiarrhythmic properties of a para-hydroxy[bis(ortho-morpholinylmethyl)]phenyl-1,4-DHP compound: comparison with other compounds of the same kind and relationship with logP values. European journal of medicinal chemistry, 2010, Volume: 45, Issue:10 Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Heart Rate; Male; Morpholines; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24 Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Modulation of venous tone in heart failure. American heart journal, 1991, Volume: 121, Issue:6 Pt 2 Topics: Captopril; Felodipine; Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Milrinone; Phosphodiesterase Inhibitors; Pyridones; Vasodilation; Vasodilator Agents	1991
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats. Chronobiology international, 1993, Volume: 10, Issue:6 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes	1993
Antihypertensive therapy and adaptive mechanisms in peripheral ischemia. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:5 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Capillaries; Captopril; Felodipine; Hindlimb; Iliac Artery; Imidazoles; Ischemia; Losartan; Male; Muscle, Smooth, Vascular; Muscles; Rats; Rats, Inbred SHR; Tetrazoles	1993
Hypertension Optimal Treatment (HOT) trial. Lancet (London, England), 1998, Aug-15, Volume: 352, Issue:9127 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Cerebrovascular Disorders; Databases as Topic; Felodipine; Humans; Hypertension; Placebo Effect; Regression Analysis	1998
[New discoveries on target blood pressure and ACE inhibitors. Swedish guidelines on hypertension are still correct]. Lakartidningen, 1998, Aug-05, Volume: 95, Issue:32-33 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Felodipine; Guidelines as Topic; Humans; Hypertension; Middle Aged; Randomized Controlled Trials as Topic; Sweden	1998
Pumpkin-seed oil modulates the effect of felodipine and captopril in spontaneously hypertensive rats. Pharmacological research, 2000, Volume: 41, Issue:5 Topics: Animals; Antioxidants; Blood Pressure; Captopril; Cucurbitaceae; Dose-Response Relationship, Drug; Felodipine; Heart Rate; Hypertension; Male; Malondialdehyde; Plant Oils; Rats; Rats, Inbred SHR; Rats, Wistar; Superoxide Dismutase	2000
[Effect of puerarin combined with felodipine on mRNA and protein expression of apelin and APJ in renovascular hypertensive rat]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:3 Topics: Animals; Antihypertensive Agents; Apelin; Apelin Receptors; Blotting, Western; Captopril; Drug Synergism; Felodipine; Gene Expression; Hypertension, Renovascular; Intercellular Signaling Peptides and Proteins; Ischemia; Isoflavones; Kidney; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasodilator Agents	2013