Page last updated: 2024-08-23

captopril and enkephalin, methionine

captopril has been researched along with enkephalin, methionine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199024 (64.86)18.7374
1990's9 (24.32)18.2507
2000's1 (2.70)29.6817
2010's2 (5.41)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Gintzler, AR; Sublette, E1
Arai, Y; Ghoda, K; Kajita, T; Liu, XF; Matsumiya, T; Ohgiya, N; Oka, T; Taniguchi, T1
Ishikawa, K; Martinez, JL; Shibanoki, S; Weinberger, SB2
Bueno, L; Liberge, M; Murillo-Lopez, D; Rivière, PJ1
Kuno, Y; Oka, T1
Ehrenpreis, S1
Altiere, RJ; Crooks, PA; Gillespie, MN; Krechniak, JW; Olson, JW1
Autry, WL; Barbaz, BS; Norman, JA1
Aoki, K; Kajiwara, M; Oka, T1
Faermark, IF; Shvarts, GIa1
Hiranuma, T; Oka, T1
Aoki, K; Cui, SY; Ishii, K; Kajiwara, M; Matsumiya, T; Oka, T; Sakamoto, J1
Gros, C; Llorens-Cortes, C; Schwartz, JC1
Fei, H; Han, JS; Zhou, ZF2
Antonaccio, MJ; Greenberg, R; O'Keefe, EH1
Chou, J; Costa, E; Del Rio, J; Tang, J; Yang, HY1
Corbett, AD; Kosterlitz, HW; McKnight, AT1
Chou, J; Costa, E; Tang, J1
Di Nicolantonio, R; Hutchinson, JS; Takata, Y; Veroni, M1
Chang, HL; Inoki, R; Kudo, T; Maeda, S; Nakamae, J; Uchida, Y1
Chou, J; Costa, E; Tang, J; Yang, HY1
Manwaring, D; Mullane, K1
Costa, E; Harsing, LG; Majane, EM; Yang, HY1
Costa, E; Stine, SM; Yang, HY1
Laubie, M; Schmitt, H1
Harty, GJ; Yaksh, TL1
Botyánszki, J; Fehér, E; Hepp, J; Magyar, A; Medzihradszky, K; Rónai, AZ1
Chiba, Y; Misawa, M1
Kishioka, S; Masuda, Y; Miyamoto, Y; Ozaki, M; Yamamoto, H1
Hiranuma, T; Iwao, K; Kitamura, K; Matsumiya, T; Oka, T1
Fan, XT; Kitamura, K; Oka, T; Taniguchi, T1
Jin, XL; Kobayashi, H; Kosaka, K; Oka, T; Takahashi, S; Yoshikawa, M1
Ahmadiani, A; Arabanian, SA; Balalaie, S; Khalaj, L; Nasoohi, S; Rezaee, Z1
Kawaguchi, M; Kobayashi, H; Murata, T; Suzuki, T; Takahashi, S; Watanabe, M; Yoshikawa, M1
Brandner, DD; Dick, RM; Gauthier, EA; Kocharian, A; Lefevre, EM; Mashal, MA; More, SS; Remmers, BC; Retzlaff, CL; Rothwell, PE; Toddes, C; Trieu, BH; Xie, W; Zhang, Y1

Other Studies

37 other study(ies) available for captopril and enkephalin, methionine

ArticleYear
Stimulus frequency and intensity: critical determinants of opioid enhancement or inhibition of evoked methionine-enkephalin release.
    Brain research, 1992, Dec-18, Volume: 599, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Captopril; Cyclic AMP; Dipeptides; Electric Stimulation; Enkephalin, Methionine; Guinea Pigs; In Vitro Techniques; Leucine; Muscle, Smooth; Myenteric Plexus; Protease Inhibitors; Pyrrolidines; Thiorphan

1992
Effects of the subcutaneous administration of enkephalins on tail-flick response and righting reflex of developing rats.
    Brain research. Developmental brain research, 1992, Oct-23, Volume: 69, Issue:2

    Topics: Aging; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Female; Glycopeptides; Injections, Subcutaneous; Male; Oligopeptides; Pain; Peptides; Posture; Protease Inhibitors; Rats; Rats, Wistar; Reflex

1992
Further characterization of the in vitro hydrolysis of [Leu]- and [Met]enkephalin in rat plasma: HPLC-ECD measurement of substrate and metabolite concentrations.
    Regulatory peptides, 1991, Feb-26, Volume: 32, Issue:3

    Topics: Amino Acids; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Endopeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains

1991
HPLC-ECD determination of the enzymatic hydrolysis of [leu]- and [met]enkephalin in rat plasma.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Acetylcholinesterase; Aminopeptidases; Animals; Captopril; CD13 Antigens; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Leucine; Male; Oligopeptides; Rats; Rats, Inbred Strains; Thiorphan; Tyrosine

1990
Opposite central and peripheral control by endogenous opioids of intestinal motility in fed rats.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Administration, Oral; Animals; Captopril; Electromyography; Endorphins; Enkephalin, Methionine; Gastrointestinal Motility; Glycopeptides; Injections, Intraperitoneal; Injections, Intraventricular; Levallorphan; Male; Naloxone; Rats; Rats, Inbred Strains

1989
Estimation of relative importance of three enzymes in the inactivation of [Met5]-enkephalin and [Met5]-enkephalin-Arg6 in three isolated preparations by employing the inhibitor specific for each enzyme.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:3

    Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Methionine; Enkephalins; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Male; Metalloendopeptidases; Mice; Mice, Inbred ICR; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Vas Deferens

1987
Pharmacology of enkephalinase inhibitors: animal and human studies.
    Acupuncture & electro-therapeutics research, 1985, Volume: 10, Issue:3

    Topics: Acupuncture Therapy; Animals; Bacitracin; beta-Endorphin; Brain; Captopril; Endorphins; Enkephalin, Methionine; Guinea Pigs; Leucine; Mice; Neprilysin; Nociceptors; Phenylalanine; Protease Inhibitors; Puromycin; Spinal Cord; Structure-Activity Relationship; Synaptic Transmission

1985
Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3

    Topics: Aminopeptidases; Animals; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; In Vitro Techniques; Leucine; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Tyrosine

1985
Angiotensin-converting enzyme inhibitors potentiate the analgesic activity of [Met]-enkephalin-Arg6-Phe7 by inhibiting its degradation in mouse brain.
    Molecular pharmacology, 1985, Volume: 28, Issue:6

    Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Enalapril; Enalaprilat; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Peptidyl-Dipeptidase A; Synaptic Membranes; Thiorphan; Tiopronin

1985
The inactivation of [Met5]-enkephalin by bestatin-sensitive aminopeptidase, captopril-sensitive peptidyl dipeptidase A and thiorphan-sensitive endopeptidase-24.11 in mouse vas deferens.
    Japanese journal of pharmacology, 1986, Volume: 40, Issue:2

    Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endopeptidases; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Thiorphan; Tiopronin; Vas Deferens

1986
[Influence of captopril on the in vitro and in vivo effects of leu- and met-enkephalins].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:6

    Topics: Animals; Captopril; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Enkephalin, Leucine; Enkephalin, Methionine; Female; Guinea Pigs; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Pain; Time Factors

1987
Effects of peptidase inhibitors on the [Met5]-enkephalin hydrolysis in ileal and striatal preparations of guinea-pig: almost complete protection of degradation by the combination of amastatin, captopril and thiorphan.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Captopril; Corpus Striatum; Enkephalin, Methionine; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Male; Membranes; Oligopeptides; Peptides; Protease Inhibitors; Thiorphan; Tiopronin

1986
The enhancing effects of amastatin, phosphoramidon and captopril on the potency of [Met5]-enkephalin in rat vas deferens.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Captopril; Electric Stimulation; Enkephalin, Methionine; Glycopeptides; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Naloxone; Oligopeptides; Peptides; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens

1986
Study of endogenous Tyr-Gly-Gly, a putative enkephalin metabolite, in mouse brain: validation of a radioimmunoassay, localisation and effects of peptidase inhibitors.
    European journal of pharmacology, 1985, Dec-17, Volume: 119, Issue:3

    Topics: Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Mice; Microwaves; Nalorphine; Neprilysin; Oligopeptides; Protease Inhibitors; Radioimmunoassay; Thiorphan; Tiopronin

1985
[Met-enkephalin-Arg6-Phe7 like immunoreactive substances in periaqueductal gray of the rabbit have an analgesic effect and participate in electroacupuncture analgesia].
    Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:1

    Topics: Acupuncture Therapy; Adjuvants, Immunologic; Animals; Captopril; Electric Stimulation Therapy; Enkephalin, Methionine; Immune Sera; Periaqueductal Gray; Rabbits; Transcutaneous Electric Nerve Stimulation

1985
The effect of captopril and ascorbic acid on nonenzymatic methionine enkephalin inactivation in the guinea-pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Animals; Ascorbic Acid; Captopril; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Proline; Puromycin; Sodium Hypochlorite; Teprotide

1981
Action of peptidase inhibitors on methionine5-enkephalin-arginine6-phenylalanine7 (YGGFMRF) and methionine5-enkephalin (YGGFM) metabolism and on electroacupuncture antinociception.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: Acupuncture Therapy; Analgesia; Animals; Captopril; Electronarcosis; Enkephalin, Methionine; Leucine; Male; Perfusion; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Thiorphan; Tiopronin

1984
Increase in potencies of opioid peptides after peptidase inhibition.
    European journal of pharmacology, 1983, Jan-21, Volume: 86, Issue:3-4

    Topics: Animals; beta-Endorphin; Captopril; Dipeptides; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Leucine; Male; Mice; Myenteric Plexus; Protease Inhibitors; Rats; Rats, Inbred Strains; Vas Deferens

1983
Met5-enkephalin-arg6-phe7 content of human and rabbit plasma.
    Life sciences, 1983, May-30, Volume: 32, Issue:22

    Topics: Adult; Animals; Captopril; Chromatography, Gel; Chromatography, High Pressure Liquid; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Methionine; Female; Half-Life; Humans; Male; Middle Aged; Rabbits

1983
Captopril potentiates the vasodepressor action of Met-enkephalin in the anaesthetized rat.
    British journal of pharmacology, 1983, Volume: 80, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Methionine; Male; Proline; Rats; Rats, Inbred Strains

1983
Changes of the Met-enkephalin-like peptide content induced by noxious stimuli in the rat incisor pulp.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Animals; Captopril; Cycloheximide; Dental Caries; Dental Pulp; Dogs; Enkephalin, Methionine; Esters; Gabexate; Guanidines; Guinea Pigs; Incisor; Protease Inhibitors; Rats

1983
Increase of striatal Met5-enkephalin-Arg6-Phe7 (YGGFMRF) content elicited by long-term treatment with haloperidol.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:1

    Topics: Animals; Captopril; Corpus Striatum; Enkephalin, Methionine; Haloperidol; Male; Rats; Rats, Inbred Strains; Time Factors; Tissue Distribution

1984
Disappearance of enkephalins in the isolated perfused rat lung.
    Life sciences, 1984, Oct-22, Volume: 35, Issue:17

    Topics: Angiotensin I; Angiotensin II; Animals; Biological Assay; Captopril; Colon; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Indomethacin; Lung; Perfusion; Prostaglandins; Rats; Rats, Inbred Strains; Stomach

1984
Met-enkephalin-Arg6-Phe7-like immunoreactive substances mediate electroacupuncture analgesia in the periaqueductal gray of the rabbit.
    Brain research, 1984, Nov-26, Volume: 322, Issue:2

    Topics: Acupuncture Therapy; Animals; Brain Mapping; Captopril; Combined Modality Therapy; Electric Stimulation Therapy; Enkephalin, Methionine; Male; Naloxone; Pain; Pain Management; Periaqueductal Gray; Rabbits

1984
Possible role of dipeptidyl carboxypeptidase n the metabolism of Met5-enkephalin and Met5-enkephalin-Arg6-Phe7.
    Advances in biochemical psychopharmacology, 1982, Volume: 33

    Topics: Animals; Captopril; Cattle; Chlorides; Corpus Striatum; Endopeptidases; Enkephalin, Methionine; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1982
Inhibition of in situ metabolism of [3H](met5)-enkephalin and potentiation of (met5)-enkephalin analgesia by captopril.
    Brain research, 1980, Apr-21, Volume: 188, Issue:1

    Topics: Animals; Behavior, Animal; Captopril; Corpus Striatum; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; Proline; Rats

1980
Indication for central vagal endorphinergic control of heart rate in dogs.
    European journal of pharmacology, 1981, May-22, Volume: 71, Issue:4

    Topics: Analgesia; Animals; Brain; Captopril; Dipeptides; Dogs; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Heart Rate; Male; Oligopeptides; Phenylalanine; Physostigmine; Potassium; Puromycin; Vagus Nerve; Veratridine

1981
Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5] enkephalin.
    European journal of pharmacology, 1982, Apr-23, Volume: 79, Issue:3-4

    Topics: Amino Acids, Sulfur; Analgesics; Animals; Captopril; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Injections, Spinal; Macaca; Morphine; Neprilysin; Protease Inhibitors; Rats; Species Specificity; Thiorphan; Tiopronin

1982
Substrate- and inhibitor-specificity of a non-endothelial enzyme which forms [Met5]-enkephalin from [Met5]-enkephalin-Arg6,Phe7 in isolated rabbit ear artery: pharmacological characterization.
    Neuropeptides, 1995, Volume: 28, Issue:3

    Topics: Amino Acid Sequence; Angiotensin I; Animals; Arteries; Bradykinin; Captopril; Disease Models, Animal; Ear, External; Enalapril; Endopeptidases; Endothelium, Vascular; Enkephalin, Methionine; Male; Migraine Disorders; Molecular Sequence Data; Rabbits; Substrate Specificity; Thiorphan

1995
Antigen-induced airway hyperresponsiveness is associated with airway tissue NEP hypoactivity in rats.
    Life sciences, 1994, Volume: 55, Issue:24

    Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris suum; Bronchial Hyperreactivity; Capsaicin; Captopril; Enkephalin, Methionine; Glycopeptides; Male; Neprilysin; Peptidyl-Dipeptidase A; Puromycin; Rats; Rats, Wistar; Respiratory System; Specific Pathogen-Free Organisms

1994
Effect of some peptidase inhibitors on exogenous and endogenous opioid actions in guinea-pig ileum.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1

    Topics: Aminopeptidases; Animals; Bacitracin; Captopril; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Ileum; Leucine; Male; Morphine; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Thiorphan

1994
Almost complete protection from [Met5]-enkephalin-Arg6-Gly7-Leu8 (Met-enk-RGL) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Captopril; Corpus Striatum; Enkephalin, Methionine; Glycopeptides; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Kinetics; Male; Morphine; Peptides; Protease Inhibitors

1997
Effects of peptidase inhibitors on the enkephalin-induced anti-nociception in rats.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enkephalin, Methionine; Glycopeptides; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar

1998
The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:1

    Topics: Analgesics; Animals; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Methionine; Glycopeptides; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar

2007
Antinociceptive effect of [Met5]enkephalin semicarbazide is not affected by dipeptidyl carboxypeptidase-I.
    Journal of peptide science : an official publication of the European Peptide Society, 2012, Volume: 18, Issue:2

    Topics: Analgesics; Animals; Biotransformation; Captopril; Carboxypeptidases; Enkephalin, Methionine; Glycopeptides; Hydrolysis; Injections, Spinal; Male; Nociception; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Semicarbazides

2012
Potentiation of [Met5]enkephalin-induced antinociception by mixture of three peptidase inhibitors in rat.
    Journal of anesthesia, 2014, Volume: 28, Issue:5

    Topics: Analgesics; Animals; Captopril; Drug Synergism; Enkephalin, Methionine; Glycopeptides; Male; Narcotic Antagonists; Peptides; Protease Inhibitors; Rats; Rats, Wistar

2014
Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid.
    Science (New York, N.Y.), 2022, 03-11, Volume: 375, Issue:6585

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Captopril; Enkephalin, Methionine; Female; Fentanyl; Male; Mice; Miniature Postsynaptic Potentials; Neuronal Plasticity; Nucleus Accumbens; Opioid Peptides; Patch-Clamp Techniques; Peptidyl-Dipeptidase A

2022