Page last updated: 2024-08-23

captopril and cyclosporine

captopril has been researched along with cyclosporine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.54)18.2507
2000's9 (34.62)29.6817
2010's12 (46.15)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Alciati, E; Casciani, CU; Pieragostini, E; Pisani, F; Tisone, G; Vennarecci, G1
Andreu, J; Campistol, JM; Montesinos, M; Oppenheimer, F; Rogada, AG; Torregrosa, JV1
Curtis, JJ; Gaston, RS; Jones, PA; Julian, BA; Laskow, DA; Luke, RG1
Chen, H; Hu, W; Li, L; Liu, Z; Tang, Z; Wang, Q; Yao, X; Yin, G1
Cerullo, G; Di Paolo, S; Gesualdo, L; Grandaliano, G; Paolo Schena, F; Schena, A; Soccio, M; Stallone, G1
Donia, A; El-Basuony, F; El-Husseini, A; Hassan, N; Mahmoud, I; Sabry, A; Sayed-Ahmad, N; Sheashaa, H; Sobh, M1
Bush, ED; Fabian, E; Herold, M; Kamp, HG; Krennrich, G; Looser, R; Mattes, WB; Mellert, W; Moeller, N; Nadanaciva, S; Naraoka, H; Omura, K; Piccoli, SP; Prokoudine, A; Ruiz-Noppinger, P; Schuppe-Koistinen, I; Strauss, V; van Ravenzwaay, B; Walk, T1
El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R1
Agunloye, OM; Bello, GT; Oboh, G; Oyagbemi, AA1

Reviews

2 review(s) available for captopril and cyclosporine

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for captopril and cyclosporine

ArticleYear
Role of ACE inhibitors in the treatment of erythrocytosis in patients with renal allograft.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Azathioprine; Captopril; Cyclosporine; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Hematocrit; Humans; Immunosuppression Therapy; Kidney Transplantation; Male; Middle Aged; Polycythemia; Postoperative Complications; Steroids; Time Factors

1994
Efficacy of captopril on posttransplant erythrocytosis. Long-term follow-up.
    Transplantation, 1994, Aug-15, Volume: 58, Issue:3

    Topics: Adult; Captopril; Cyclosporine; Erythrocyte Indices; Female; Follow-Up Studies; Hematocrit; Hemoglobins; Humans; Kidney Transplantation; Male; Middle Aged; Polycythemia; Time Factors

1994
Captopril-induced fall in glomerular filtration rate in cyclosporine-treated hypertensive patients.
    Journal of the American Society of Nephrology : JASN, 1993, Volume: 3, Issue:9

    Topics: Adult; Blood Pressure; Captopril; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Transplantation; Male; Nifedipine; Postoperative Period

1993
Cyclosporin A treatment for idiopathic membranous nephropathy.
    Chinese medical journal, 2001, Volume: 114, Issue:12

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Creatinine; Cyclosporine; Female; Follow-Up Studies; Glomerulonephritis, Membranous; Humans; Immunosuppressive Agents; Male; Middle Aged; Prospective Studies; Remission Induction; Treatment Outcome

2001
Captopril enhances transforming growth factor (TGF)-beta1 expression in peripheral blood mononuclear cells: a mechanism independent from angiotensin converting enzyme inhibition? A study in cyclosporine-treated kidney-transplanted patients.
    Transplantation, 2002, Dec-27, Volume: 74, Issue:12

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cyclosporine; Drug Therapy, Combination; Female; Gene Expression; Genotype; Humans; Immunosuppressive Agents; In Vitro Techniques; Kidney Transplantation; Leukocytes, Mononuclear; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1

2002

Other Studies

19 other study(ies) available for captopril and cyclosporine

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:1

    Topics: Adolescent; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Child, Preschool; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Ketoconazole; Male; Nephrotic Syndrome; Retrospective Studies; Steroids

2006
Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.
    BioMed research international, 2013, Volume: 2013

    Topics: Animals; Captopril; Cyclosporine; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Kidney Diseases; Lisinopril; Male; Metabolome; Metabolomics; Phenytoin; Rats; Rats, Wistar

2013
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity.
    Life sciences, 2016, Oct-15, Volume: 163

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation

2016
Caffeic and chlorogenic acids modulate altered activity of key enzymes linked to hypertension in cyclosporine-induced hypertensive rats.
    Journal of basic and clinical physiology and pharmacology, 2020, Oct-01, Volume: 32, Issue:3

    Topics: 5'-Nucleotidase; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Caffeic Acids; Captopril; Chlorogenic Acid; Cyclosporine; Hypertension; Male; Malondialdehyde; Peptidyl-Dipeptidase A; Rats; Rats, Wistar

2020