captopril has been researched along with chlorthalidone in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (53.33) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Balbi, AL; Franco, RJ; Luna, RL; Martin, LC; Sampaio, M | 1 |
| Aguilera, MT; Closas, J; Coca, A; de la Sierra, A; Sánchez, M; Sobrino, J; Urbano-Márquez, A | 1 |
| Basciu, M; Cherchi, A; Pili, G; Sau, F; Seguro, C; Siddi, PP; Tamponi, R | 1 |
| Belovezhdov, N; Monova, D | 1 |
| Gabbani, S; Galeone, F; Giuntoli, F; Natali, A; Saba, P | 1 |
| Laragh, JH; Niarchos, AP; Resnick, LM; Weinstein, DL | 1 |
| Agabiti-Rosei, E; Alicandri, C; Buoninconti, R; Cagli, V; Carotti, A; Corea, L; Dal Palù, C; Innocenti, PF; Muiesan, G; Paciaroni, E | 1 |
| Dorfman, B; Krakowski, A; Wolf, R | 1 |
| Morganti, A; Palermo, A; Sala, C; Turolo, L; Zanchetti, A | 1 |
| Petrella, V | 1 |
| Antoncecchi, E; Balestrazzi, M; Chiarappa, R; De Cesaris, R; Ranieri, G | 1 |
| Agretto, A; De Stefano, R; Manzo, M; Russo, G; Villani, C; Vitale, P | 1 |
| Catalano, M; Libretti, A | 1 |
| Conway, J | 1 |
| Foppoli, C; Fusco, M; Lombardo, M; Pacini, S; Pastori, F; Zaini, G | 1 |
| Brunner, HR; Gavras, H; Waeber, B | 1 |
| Aguglia, F; Ficara, C; Santucci, A | 1 |
| Agabiti-Rosei, E; Alicandri, C; Boni, E; Cinquegrana, A; Fariello, R; Montini, E; Muiesan, G; Muiesan, ML; Zaninelli, A | 1 |
| Ambrosioni, E; Borghi, C; Costa, FV | 1 |
| Eerdmans, PH; Janssen, BJ; Smits, JF | 1 |
| Baptista, M; Costa, CH; Kohlmann Júnior, O; Kohlmann, NE; Ribeiro, AB; Zanella, MT | 1 |
1 review(s) available for captopril and chlorthalidone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
10 trial(s) available for captopril and chlorthalidone
| Article | Year |
|---|---|
[An open comparative study of captopril + hydrochlorothiazide versus chlorthalidone for the treatment of mild and moderate primary hypertension].
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Chi-Square Distribution; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged | 1992 |
[Electrocardiographic and echocardiographic changes during antihypertensive therapy].
Topics: Acebutolol; Adolescent; Adult; Aged; Antihypertensive Agents; Captopril; Cardiomegaly; Chlorthalidone; Echocardiography; Electrocardiography; Female; Humans; Hypertension; Indenes; Male; Middle Aged; Nifedipine; Oxprenolol; Pindolol; Propanolamines; Timolol | 1990 |
A multicenter trial of low dose captopril administered twice daily in patients with essential hypertension unresponsive to beta blocker-diuretic treatment.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Captopril; Chlorthalidone; Clinical Trials as Topic; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension | 1987 |
Captopril in the treatment of hypertension associated with claudication.
Topics: Blood Pressure; Captopril; Chlorthalidone; Female; Heart Rate; Humans; Hypertension; Intermittent Claudication; Male; Middle Aged; Physical Exertion | 1986 |
Third-line therapy. A cautionary note.
Topics: Atenolol; Bendroflumethiazide; Captopril; Chlorthalidone; Female; Humans; Hypertension; Male; Methyldopa; Nifedipine | 1985 |
Left ventricular mass and function before and after antihypertensive treatment.
Topics: Adult; Captopril; Cardiomegaly; Chlorthalidone; Drug Therapy, Combination; Echocardiography; Female; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Proline | 1983 |
[Clinical experience with a new antihypertensive drug (captopril SQ 14.225), an oral inhibitor of converting enzyme].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Chlorthalidone; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin | 1981 |
Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolled by a beta blocker plus thiazide diuretic.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Captopril; Chlorthalidone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Proline; Renin | 1984 |
Captopril and oxprenolol in a fixed combination with thiazide diuretics: comparison of their antihypertensive efficacy and metabolic effects.
Topics: Adult; Blood Pressure; Captopril; Chlorthalidone; Cholesterol; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Proline; Random Allocation | 1984 |
[Comparative effects of captopril and chlorthalidone on glucose tolerance and insulin levels essential hypertensives].
Topics: Adolescent; Adult; Aged; Analysis of Variance; Blood Glucose; Captopril; Chlorthalidone; Female; Glucose Tolerance Test; Humans; Hypertension; Hypokalemia; Insulin; Male; Middle Aged | 1996 |
19 other study(ies) available for captopril and chlorthalidone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
[Do clinical parameters exist that permit predicting the need to combine a diuretic with captopril in the initial treatment of essential arterial hypertension?].
Topics: Adult; Aged; Blood Pressure; Captopril; Chlorthalidone; Diet, Sodium-Restricted; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prognosis | 1990 |
[Captopril from Pharmachem in the treatment of arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Captopril; Chlorthalidone; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tablets; Time Factors | 1989 |
Captopril treatment in elderly hypertensive patients: efficacy and tolerability. Captopril Study Group.
Topics: Aged; Captopril; Chlorthalidone; Drug Therapy, Combination; Drug Tolerance; Female; Heart Rate; Humans; Hypertension; Male; Time Factors | 1989 |
Angiotensin I converting enzyme activity in hypertension. Relationship to blood pressure, renin-sodium profiles, and antihypertensive therapy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Captopril; Chlorthalidone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Natriuresis; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1985 |
Psoriasiform eruption induced by captopril and chlorthalidone.
Topics: Aged; Captopril; Chlorthalidone; Drug Eruptions; Female; Humans; Hypertension; Male; Middle Aged; Psoriasis | 1987 |
Participation of the renin-angiotensin system in the maintenance of blood pressure during changes in posture in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Chlorthalidone; Diuretics; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Posture; Proline; Renin; Renin-Angiotensin System; Sodium | 1985 |
[Thrombocytopenia caused by drugs: new molecules as the cause].
Topics: Aged; Aged, 80 and over; Atenolol; Captopril; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hypertension; Middle Aged; Thrombocytopenia | 1987 |
[Comparison of nadolol and chlorthalidone in hypertensive subjects resistant to therapy with only captopril].
Topics: Adult; Aged; Antihypertensive Agents; Captopril; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Nadolol; Propanolamines | 1986 |
[Captopril in the treatment of arterial hypertension in the elderly patient].
Topics: Aged; Captopril; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged | 1986 |
Enhancement by diuretics of the antihypertensive action of long-term angiotensin converting enzyme blockade.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Child; Chlorthalidone; Diuretics; Drug Synergism; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Kidney Failure, Chronic; Male; Middle Aged; Minoxidil; Proline; Propranolol; Renal Dialysis; Renin; Sodium | 1980 |
Mechanisms of renal vasoconstriction following furosemide in conscious rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Chlorthalidone; Dose-Response Relationship, Drug; Drug Interactions; Furosemide; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Wistar; Regional Blood Flow; Renal Artery; Tetrazoles; Vascular Resistance; Vasoconstriction | 1994 |