captopril has been researched along with bradykinin in 394 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 156 (39.59) | 18.7374 |
| 1990's | 163 (41.37) | 18.2507 |
| 2000's | 50 (12.69) | 29.6817 |
| 2010's | 23 (5.84) | 24.3611 |
| 2020's | 2 (0.51) | 2.80 |
| Authors | Studies |
|---|---|
| Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 2 |
| Lefer, AM; Trachte, GJ | 1 |
| Nakano, T; Taira, N | 1 |
| Johnston, CI; Matthews, PG; McGrath, BP | 1 |
| Antonaccio, MJ; Greenberg, R; O'Keefe, EH; Osman, GH | 2 |
| Kato, E; Kondo, K; Konishi, K; Okuno, T; Saruta, T | 2 |
| Johnston, CI; Matthews, PG | 1 |
| Auch-Schwelk, W; Bossaller, C; Claus, M; Fleck, E; Graf, K; Gräfe, M | 1 |
| Conlon, JM; Gao, XP; Koizumi, S; Mayhan, WG; Rennard, SI; Rubinstein, I; Yong, T | 1 |
| Auch-Schwelk, W; Baumgarten, C; Bossaller, C; Fleck, E; Graf, K; Gräfe, M | 1 |
| Becker, RH; Schölkens, BA; Wiemer, G | 1 |
| Katori, M; Mohsin, SS; Sharma, JN; Stewart, JM; Vavrek, R | 1 |
| Håkanson, R; Wang, ZY | 1 |
| Arakawa, K; Ideishi, M; Ikeda, M; Noda, K; Sasaguri, M | 2 |
| Jin, HY; Katori, M; Majima, M; Sunahara, N | 1 |
| Müller, B; Müller, M; Overlack, A; Scheid, ML; Schmidt, L; Stumpe, KO | 2 |
| Bennett, T; Gardiner, SM | 1 |
| Katori, M; Majima, M; Shima, C | 1 |
| Félétou, M; Germain, M; Teisseire, B | 1 |
| Andreoni, AS; Batista, MB; Ferreira, LA; Habermehl, G; Henriques, OB; Lebrun, I; Prezoto, BC; Zelnik, R | 1 |
| Carretero, O; Fenoy, FJ; Roman, RJ; Scicli, G | 1 |
| Becker, BF; Gerlach, E; Leipert, B; Raschke, P; Reinholz, N | 1 |
| Chow, A; Drapeau, G; Ward, PE | 1 |
| Criscuoli, M; Guelfi, M; Subissi, A | 1 |
| Bönner, G; Kaufmann, W; Preis, S; Schunk, U; Toussaint, C | 1 |
| Rani, R; Rao, KS | 1 |
| de Graeff, PA; de Leeuw, MJ; Scholtens, E; van Gilst, WH; Wesseling, H | 1 |
| Katsumata, U; Sasaki, H; Sekizawa, K; Takishima, T; Ujiie, Y | 1 |
| Bühler, FR; Kiowski, W; Kleinbloesem, C; Linder, L; van Brummelen, P | 1 |
| Caldo, H; Rodrigues, MC; Salgado, MC | 1 |
| Barnes, PJ; Chung, KF; Lötvall, JO; Tokuyama, K | 1 |
| Carlson, RP; Chau, TT; Lewin, AC; Walter, TL; Weichman, BM | 1 |
| Beleslin, BD; Japundzić, N; Jovanović-Mićić, D; Prostran, M; Samardzić, R; Todorović, Z | 1 |
| Hajj-ali, AF; Zimmerman, BG | 1 |
| Kerkhoff, J; van den Buuse, M | 1 |
| Fregly, MJ; Rowland, NE | 2 |
| Carretero, OA; Longhurst, JC; Mindroiu, T; Stebbins, CL | 1 |
| McGraw, DE; Smits, GJ; Trapani, AJ | 1 |
| Bönner, G; Düsing, R; Göbel, BO; Hoffmann, G; Pietsch, R; Vetter, H; Weisser, B | 1 |
| Eckhardt, M; Griesbacher, T; Lembeck, F | 1 |
| Iijima, M; Kajiwara, Y; Kitabatake, K; Shirota, M | 1 |
| Dietze, GJ; Rett, K; Tio, RA; van Gilst, WH; Wesseling, H; Wolters, K | 1 |
| Lipke, DW; Olson, KR; Oparil, S | 1 |
| Carretero, OA; Scicli, AG | 1 |
| Anderson, MW; deShazo, RD | 1 |
| Braso, MA; Gubert, S; Ortiz, JA; Sacristán, A | 1 |
| Center, DM; Danilov, SM; Farber, HW; Rounds, S | 1 |
| Arakawa, K; Ideishi, M; Ikeda, M; Sasaguri, M | 1 |
| Barer, GR; Cai, YN; Emery, CJ; Howard, P; Russell, PC | 1 |
| Barnes, PJ; Ichinose, M | 1 |
| Ferreira, SH; Lopes, OU; Pontieri, V | 1 |
| Dai, S; Hui, SC; Ogle, CW | 1 |
| Longhurst, JC; Stebbins, CL | 1 |
| Li, T; Rassier, ME; Zimmerman, BG | 1 |
| Marumo, F; Nara, Y | 1 |
| Teng, CM; Wang, JP | 1 |
| Cushman, DW; DeForrest, JM; Harvey, C; Petrillo, EW; Powell, JR; Rubin, B; Scalese, B; Waldron, TL | 1 |
| Hirose, K; Hori, Y; Jyoyama, H; Kageyama, H; Katori, M; Kurosawa, A; Yamada, K | 1 |
| Almond, NE; Cooke, ED; Li Kam Wa, TC; Turner, P | 1 |
| Iimura, O; Shimamoto, K | 1 |
| Ferner, RE; Paterson, JR; Rawlins, MD; Wilkinson, R; Wilson, D | 1 |
| Beierwaltes, WH; Carretero, OA | 1 |
| Ito, Y; Kasugai, M; Kurauchi, O; Mizutani, S; Narita, O; Nomura, S; Tomoda, Y | 1 |
| de Langen, CD; Scholtens, E; Tio, RA; van Gilst, WH; van Wijngaarden, J; Wesseling, H | 1 |
| Abe, K; Fang, SN; Kanazawa, M; Kasai, Y; Omata, K; Sato, M; Takeuchi, K; Yasujima, M; Yoshinaga, K | 1 |
| de Langen, CD; Heiligers, JP; König, W; Saxena, PR; Tio, RA; van Gilst, WH; Wesseling, H | 1 |
| Kawamura, K; Kubo, S; Kubota, J; Nishimura, H; Ueyama, M | 1 |
| Abe, K; Nushiro, N; Omata, K; Seino, M; Yoshinaga, K | 1 |
| Griesbacher, T; Lembeck, F; Saria, A | 1 |
| Hasegawa, K; Inoue, S; Kakumae, S; Kawahara, Y; Nakamura, T; Nezuo, S; Sawayama, T; Tadaoka, S | 1 |
| Hayashi, I; Hayashi, M; Nakano, T; Oh-ishi, S; Utsunomiya, I; Yamaki, K; Yamasu, A | 1 |
| Katori, M; Majima, M; Sunahara, N; Ueno, A | 1 |
| Boura, AL; King, RG; Lau, WA; Rechtman, MP | 1 |
| Bendhack, LM; Lindsey, CJ; Paiva, AC | 1 |
| Carretero, OA; Erdös, EG; Ura, N | 1 |
| Nakagawa, M; Nakamura, Y; Nakanishi, Y; Sasaki, S; Sawada, S; Takamatsu, H; Takeda, K; Toyoda, T; Tsuji, H; Uno, M | 1 |
| Wahl, M; Whalley, ET | 1 |
| Adamski, SW; Grega, GJ | 1 |
| Kamo, I; Kumakura, S; Tsurufuji, S | 1 |
| Goering, JL; Raich, PC; Zimmerman, BG | 1 |
| de Nucci, G; Vane, JR; Warner, T | 1 |
| Wahl, M | 1 |
| Barabé, J; D'Orléans-Juste, P; Dion, S; Drapeau, G; Regoli, D; Rhaleb, NE; Rovero, P; Ward, P | 1 |
| Gibson, AM; McDermott, JR; Turner, JD | 1 |
| Brown, MJ; Higenbottam, T; Lowry, R; Morice, AH | 1 |
| Beierwaltes, WH; Carretero, OA; Prada, J | 1 |
| Igić, R | 1 |
| Bönner, G; Kaufmann, W; Schunk, U | 1 |
| Arakawa, K; Okuda, M | 1 |
| Damkjaer Nielsen, M; Giese, J; Ibsen, H; Leth, A; Nielsen, F; Rasmussen, S | 3 |
| Fukuya, F; Hosoki, K; Kadokawa, T; Kawahara, S; Minato, H; Takeyama, K | 1 |
| Inokuchi, J; Nagamatsu, A; Nishioka, I; Nonaka, G; Okabe, H; Yamauchi, T | 1 |
| Snyder, RA; Wintroub, BU | 1 |
| Nagaoka, I; Yamashita, T | 1 |
| Ikeda, M; Kawato, M; Koshida, H; Miyamori, I; Morise, T; Okamoto, S; Takeda, R; Takeda, Y; Yasuhara, S | 1 |
| Iimura, O; Maeda, T; Mita, T; Nakagawa, M; Nishimiya, T; Shimamoto, K; Tanaka, S; Ura, N; Yamaguchi, Y | 1 |
| Ijichi, H; Maebo, N; Nakagawa, M; Niwa, I; Sawada, S; Takamatsu, H; Toyoda, T; Tsuji, H | 1 |
| Cadieux, A; Sirois, P | 1 |
| Dietze, G; Fink, E; Jauch, KW; Mehnert, H; Rett, K; Wicklmayr, M | 1 |
| Cole, T; Conlon, M; Nau, R; Schäfer, G | 1 |
| de Deus, RB; Henriques, OB; Santos, RA | 1 |
| Ashford, A; Bailey, GS; Jaffa, AA; Pratt, J | 1 |
| Ferner, RE; Rawlins, MD; Simpson, JM | 1 |
| Zusman, RM | 1 |
| Ijichi, H; Nakagawa, M; Sawada, S; Takamatsu, H; Toyoda, T; Tsuji, H | 1 |
| Whalley, ET | 1 |
| Greenbaum, LM; Sugio, K | 1 |
| Drummer, OH; Kourtis, S | 1 |
| Abe, K; Kasai, Y; Nushiro, N; Omata, K; Seino, M; Yoshinaga, K | 1 |
| Kimura, M; Maeda, H; Matsumura, Y; Yamamoto, T | 1 |
| Nakagawa, M; Nasjletti, A | 1 |
| Chaudhari, A; Kirschenbaum, MA | 1 |
| Perry, DC | 1 |
| Kumakura, S; Kurooka, S; Sunahara, N; Tsurufuji, S | 1 |
| Janssen, HF; Lange, DL; Pugh, JL | 1 |
| Aubert, JF; Brunner, HR; Nussberger, J; Stewart, JM; Vavrek, R; Waeber, B | 1 |
| Soares de Moura, R; Solano Vale, N | 1 |
| Dostal, DE; Johnson, JA | 1 |
| Bönner, G; Schunk, U | 1 |
| Kumazawa, T; Mizumura, K; Sato, J | 1 |
| Sato, H; Schill, WB | 1 |
| Aniya, Y; Ito, H; Kato, T; Noguchi, K; Sakanashi, M | 1 |
| Center, DM; Farber, HW; Rounds, S | 1 |
| Ogawa, N; Ono, H | 1 |
| Alhenc-Gelas, F; Corvol, P; Menard, J; Yasui, T | 1 |
| Takeda, Y | 1 |
| Brunner, HR; de Agostini, A; Nussberger, J; Schapira, M; Waeber, B | 2 |
| Giese, J; Ibsen, H; Nielsen, MD; Rasmussen, S | 1 |
| Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S | 1 |
| Anderson, WP; Clappison, BH; Johnston, CI; Yasujima, M | 1 |
| Johnston, CI; Matthews, G; Yasujima, M | 1 |
| Babiuk, C; Marceau, F; Regoli, D; St-Pierre, S | 1 |
| Boschcov, P; Paiva, AC; Paiva, TB; Shimuta, SI | 1 |
| Johnston, CI; Matthews, PG; Yasujima, M | 1 |
| Hashimoto, K; Ohara, N; Ono, H | 1 |
| Hollenberg, NK | 1 |
| Sicuteri, F | 1 |
| Larsson-Backstrom, C | 1 |
| Casley, DJ; Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 1 |
| Antonaccio, MJ; Cheung, HS; Cushman, DW; Murthy, VS; Ondetti, MA; Rubin, B | 1 |
| Eguchi, T; Nakamura, R; Saito, I; Saruta, T; Yasui, T | 1 |
| Brunner, HR; Gavras, H; Textor, SC | 1 |
| Backlund, EP; Bohn, DL; Gross, DM; Morris, AA; Stone, CA; Sweet, CS; Ulm, EH; Vassil, TC; Weitz, D; Wenger, HC | 1 |
| Anderson, WP; Clappison, B; Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 1 |
| Catravas, JD; Gillis, CN | 1 |
| Iansek, R; Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 1 |
| Brunner, HR; Gavras, H; Waeber, B; Wauters, JP | 1 |
| Antonaccio, J; Rubin, B | 1 |
| Satoh, S; Suzuki, M | 1 |
| Fantone, JC; Schrier, D; Weingarten, B | 1 |
| Sheridan, MA; Ward, PE | 1 |
| Angus, JA; Johnston, CI; Nakashima, A | 2 |
| Guile, AJ; Johnson, A; Kivlen, CM; Malik, AB; Pittman, T | 1 |
| Edvinsson, L; Wagner, F; Wahl, M; Young, AR | 1 |
| Ikeda, M; Koshida, H; Miyamori, I; Morise, T; Nishino, T; Takeda, R; Takeda, Y; Takimoto, H; Yasuhara, S | 1 |
| Kivlen, CM; Malik, AB; Minnear, FL | 1 |
| De Jonge, A; Timmermans, PB; Van Zwieten, PA | 1 |
| Abe, K; Omata, K; Tanno, M; Yasujima, M; Yoshinaga, K | 1 |
| Boura, AL; Svolmanis, AP | 1 |
| Anderson, GH; Eich, R; Hill, N; Mookherjee, S; Smulyan, H; Streeten, DH; Vardan, S; Warner, R | 1 |
| Hoffman, WE; Lewis, RE; Phillips, MI | 1 |
| Fukuchi, S; Gotoh, M; Haruyama, K; Hashimoto, S; Ikeda, K; Mizuno, K | 1 |
| Adamski, SW; Grega, GJ; Su, K; Svensjö, E | 1 |
| Anderson, WP; Clappison, BH; Johnston, CI | 1 |
| Fukuchi, S; Gotoh, M; Haruyama, K; Hashimoto, S; Matsui, J; Mizuno, K; Toki, T | 1 |
| Endoh, T; Fujita, K; Hashimoto, F; Kuriyamoto, Y; Minami, M; Nishino, T; Saito, H; Sano, M; Togashi, H; Yasuda, H | 1 |
| Fukuchi, S; Gotoh, M; Haruyama, K; Matsui, J; Mizuno, K | 1 |
| Fukuchi, S; Haruyama, K; Mizuno, K; Toki, T; Yaginuma, K; Yamazaki, M | 1 |
| Mann, JF | 1 |
| Heidland, A; Schaefer, RM | 1 |
| Brown, AD; Chiu, PJ | 1 |
| Hattori, S; Kariya, K; Okada, Y; Tsuda, Y; Yamauchi, A | 1 |
| Hashimoto, K; O'Hara, N; Ono, H | 1 |
| Antonaccio, MJ; Murthy, VS; Waldron, TL | 1 |
| Bing, RF; Marks, ES; Swales, JD; Thurston, H | 1 |
| Miller, SH; Petty, MA; Reid, JL | 1 |
| Grodzińska, L; Gryglewski, RJ | 1 |
| Moncada, S; Mullane, KM | 1 |
| Ball, D; Chesney, RW; Friedman, A; Goodfriend, T | 1 |
| Antonaccio, MJ; Horovitz, ZP; Rubin, B | 1 |
| Brown, MJ; Dollery, CT; Miyamori, I | 1 |
| Knapp, MF; Linden, RJ; Mary, DA; Pearson, MJ | 1 |
| Barabé, J; Gaudreau, P; Regoli, D; St-Pierre, S | 1 |
| Martinez, P; Tunney, A; Vandongen, R | 1 |
| Fregly, MJ; Lockley, OE; Simpson, CE | 1 |
| Clarke, DE; Wagner, LA; Wagner, LB | 1 |
| Collis, MG; Keddie, JR | 1 |
| Garnic, JD; Harrington, DP; Hollenberg, NK; Katz, J; Meggs, LG; Williams, GH | 1 |
| Fukuchi, S; Gotoh, M; Matsui, J; Mizuno, K | 1 |
| Abe, K; Haruyama, T; Imai, Y; Seino, M; Sekino, H; Tajima, J; Yoshinaga, K | 1 |
| Gulati, N; Gulati, OP; Huggel, H | 1 |
| Amann, FW; Bühler, FR; Hulthén, L; Kiowski, W; van Brummelen, P | 1 |
| Ercan, ZS; Ersoy, A; Türker, RK; Zengil, H | 1 |
| Fogal, SE; Loughnan, CL; Madwed, JB; Panzenbeck, MJ; Winquist, RJ | 1 |
| Antunes, E; Burton, J; de Nucci, G; Lopes-Martins, RA; Oliva, ML; Sampaio, CA | 1 |
| Glusa, E | 1 |
| Anning, PB; Grocott-Mason, RM; Lewis, MJ; Shah, AM | 1 |
| Calixto, JB; Huidobro-Toro, JP; Maas, J; Rae, GA | 1 |
| Evans, RG; Lew, RA; Madden, AC; Perich, RB; Smith, AI; Telford, SE | 1 |
| Bönner, G; Eisenhauer, T; Fink, E; Krieter, DH; You, HM | 1 |
| de Moura, R; Lopes, MA | 1 |
| Cimmerer, AL; Fregly, MJ; Rowland, NE | 1 |
| Barnes, PJ; Chung, KF; Kwon, O; Sun, J; Tsukagoshi, H | 1 |
| Botyánszki, J; Fehér, E; Hepp, J; Magyar, A; Medzihradszky, K; Rónai, AZ | 1 |
| Carretero, OA; Longhurst, JC; Pan, HL; Rendig, SV; Stahl, GL | 1 |
| Arakawa, K; Ideishi, M; Kinoshita, A; Miura, S; Motoyama, M; Sakai, T; Sasaguri, M; Shindo, M; Tanaka, H | 1 |
| Levi, R; Rubin, LE | 1 |
| Loi, RK; Warren, JB | 1 |
| Davidson, DC; Peart, I; Sangster, M; Turner, S | 1 |
| Adam, A; Closset, J; Couture, R; Décarie, A; Drapeau, G | 1 |
| Corrêa, FM; Lebrun, FL; Lebrun, I | 1 |
| Broom, T; DeSiato, MA; Farmer, SG | 1 |
| Goto, A; Hirawa, N; Ikeda, T; Kawabata, Y; Kizuki, K; Ohshima, N; Oka, K; Suzuki, T; Toyo-oka, T; Uehara, Y | 1 |
| Feng, CJ; Kadowitz, PJ; Nossaman, BD | 1 |
| Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC | 1 |
| Garrison, EA; Kadowitz, PJ; Santiago, JA | 1 |
| Chen, K; Zimmerman, BG | 1 |
| Hirano, K; Kanaide, H | 1 |
| Leighton, HJ; Mudumbi, RV | 1 |
| Bassenge, E; Zanzinger, J; Zheng, X | 1 |
| Cardinal, R; de Champlain, J; Godin, D; Gouin, L; Moreau, P; Nadeau, R; Ribuot, C; Rochette, L; Vermeulen, M | 1 |
| Asaad, M; Rogers, WL; Seymour, AA; Sheldon, JH; Smith, PL | 1 |
| Calixto, JB; Corrêa, CR | 1 |
| Mehring, N; Neusser, M; Tepel, M; Zhu, Z; Zidek, W | 1 |
| da Silva, SV; da Silva, VJ; Salgado, HC; Salgado, MC | 1 |
| Bassenge, E; Zanzinger, J | 1 |
| Anding, P; Gao, XP; Rennard, SI; Robbins, RA; Rubinstein, I | 1 |
| Grupp, LA; Harding, S; Robertson, JM | 1 |
| Chiyotani, A; Isono, K; Konno, K; Tamaoki, J | 1 |
| Iimura, O; Miki, T; Miura, T; Sakamoto, J; Shimamoto, K; Urabe, K | 1 |
| Akaike, T; Maeda, H; Maruo, K; Sakata, Y | 1 |
| Fukuo, K; Momose, N; Morimoto, S; Ogihara, T | 1 |
| Baker, J; Bertrand, C; Geppetti, P; Nadel, JA; Petersson, G; Piedimonte, G | 1 |
| Antunes, E; Brain, SD; de Nucci, G; Marangoni, RA | 1 |
| Hirano, K; Hirano, M; Kanaide, H | 1 |
| Cooke, ED; Turner, P; Wa, TC | 1 |
| Harada, Y; Katori, M; Majima, M; Sunahara, N | 1 |
| Cooke, ED; Li Kam Wa, TC; Turner, P | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA | 1 |
| Cowley, AW; Mattson, DL | 1 |
| Augustin, HJ; Dietze, GJ; Henriksen, EJ; Jacob, S | 1 |
| Dragović, T; Erdös, EG; Jackman, HL; Minshall, R; Wang, LX | 1 |
| Faussner, A; Kasel, AM; Müller, U; Pfeifer, A; Roscher, AA; Werdan, K | 1 |
| Bergelson, BA; Gavras, H; Gavras, I; Ruocco, NA; Yu, TK | 1 |
| Allen, GT; Powell, JR; Tesfamariam, B | 1 |
| Chen, K; Dunham, EW; Zhang, X; Zimmerman, BG | 1 |
| Chang, EB; De Jonge, HR; De Vente, J; Musch, MW; Vaandrager, AB; Wilson, KT | 1 |
| Barnes, PJ; Belvisi, MG; Bernareggi, M; Chung, KF; Fox, AJ; Lalloo, UG | 1 |
| Domingues-Costa, A; Magina, S; Moura, D; Vaz-da-Silva, M | 1 |
| Duan, J; Fernandes, BH; Jaramillo, J; Jung, GL; Mathis, D; McLeod, AL | 1 |
| Chen, S; Ishii, J; Kashiwabara, H; Katayama, S; Kosegawa, I | 1 |
| Deck, CC; Gaballa, MA; Raya, TE | 1 |
| Campbell, DJ | 1 |
| Adachi, K; Katoh, K; Katori, M; Majima, M; Ogino, M; Ohno, T; Saito, M; Sugimoto, K; Sunahara, N; Takei, Y; Tatemichi, N | 1 |
| Ahmad, M; Parratt, JR; Zeitlin, IJ | 1 |
| Griesbacher, T; Lembeck, F | 1 |
| Adam, A; Cardinal, R; Drapeau, G; Gouin, L; Nadeau, R | 1 |
| Iguchi, Y; Katoh, K; Katori, M; Majima, M; Nishiyama, K; Ogino, M; Ohno, T; Sunahara, N; Takei, Y; Tatemichi, N; Yao, K | 1 |
| Evans, RG; Lew, RA; Madden, AC; Smith, AI; Tomoda, F | 1 |
| Adam, A; Couture, R; Decarie, A | 1 |
| Arakawa, M; Goto, F; Katori, M; Majima, M; Nagai, K | 1 |
| Del Bianco, A; Fregly, MJ; Rowland, NE | 1 |
| Bourdon, V; Damas, J; Liégeois, JF; Simmons, WH | 1 |
| Bellini, C; De Mattia, G; Desideri, G; Ferri, C; Santucci, A | 1 |
| Hintze, TH; Nasjletti, A; Wolin, MS; Xie, YW; Xu, X; Zhang, X | 1 |
| Antunes, E; De Nucci, G; Muscará, MN; Teixeira, SA; Zappellini, A; Zatz, R | 1 |
| Aurell, M; Johnsen, SA; Persson, IB | 1 |
| Brown, NJ; Nadeau, JH; Vaughan, DE | 1 |
| Blazsó, G; Gáspár, R | 1 |
| Bjorling, DE; Franz, J; Saban, R | 1 |
| Juji, T; Nakajima, K; Sawanobori, M; Shiba, M; Suzuki, K; Tadokoro, K | 1 |
| Morris, SD; Yellon, DM | 1 |
| Feng, CJ; Kadowitz, PJ; Kang, B; Kaye, AD; Nossaman, BD | 1 |
| Schultz, HD; Ustinova, EE; Wang, W; Zucker, IH | 1 |
| Dennis, MJ; Dixon, BS | 1 |
| Gao, XP; Olopade, CO; Pakhlevaniants, S; Rubinstein, I; Suzuki, H | 1 |
| Carvalho, CR; Gontijo, JA; Saad, MJ; Thirone, AC; Velloso, LA | 1 |
| Heller, J; Horácek, V; Kramer, HJ | 1 |
| Anania, V; Angioni, GR; Emanueli, C; Madeddu, P; Spissu, A | 1 |
| de Moura, RS; Leão, MC | 1 |
| Goto, K; Itakura, A; Kikkawa, F; Kondo, I; Kuno, N; Kurauchi, O; Mizutani, S; Ohno, Y; Tomoda, Y | 1 |
| Anning, PB; Grocott-Mason, RM; Lewis, MJ | 1 |
| Bunnett, NW; Emanueli, C; Figini, M; Geppetti, P; Grady, EF; Madeddu, P; Parisi, D; Regoli, D | 1 |
| Akiyoshi, K; Ito, M; Iwao, T; Nakagawa, M; Saikawa, T; Teshima, Y; Yasunaga, S; Yonemochi, H | 1 |
| Mather, TN; Ribeiro, JM | 1 |
| Bunnett, NW; Geppetti, P; Halliday, DA; Kaneko, T; Lovett, M; Nadel, JA; Ricciardolo, FL | 1 |
| Ishiguro, S; Kawagoe, K; Miyamoto, A; Nakamura, Y; Nishio, A; Obi, T | 1 |
| Struthers, AD | 1 |
| Brown, NJ; Gainer, JV; King, DJ; Loveland, A; Morrow, JD | 1 |
| Born, J; Dendorfer, A; Derad, I; Dominiak, P; Fehm, HL | 1 |
| Andrade, MC; Boim, MA; Carmona, AK; Casarini, DE; Quinto, BM; Ribas, OS; Schor, N | 1 |
| Bedarida, GV; Blaschke, TF; Chalon, S; Hoffman, BB; Moreno, H; Tejura, B; Urae, A | 1 |
| Baluk, P; Bunnett, NW; McDonald, DM; Murphy, TJ; Thurston, G | 1 |
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| Azizi, M | 1 |
| Agarwal, R | 1 |
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| Kokkonen, JO; Kovanen, PT; Kuoppala, A; Lindstedt, KA; Saarinen, J | 2 |
| Bourdon, V; Damas, J; Lefebvre, PJ | 1 |
| Chao, J; Chao, L; Emanueli, C; Madeddu, P; Ni, A; Regoli, D | 1 |
| Guo, ZG; Lei, BL | 1 |
| Bozza, PT; Calixto, JB; Castro-Faria-Neto, HC; Henriques, MG; Larangeira, AP; Pacheco, P; Silva, AR | 1 |
| Dietze, GJ; Henriksen, EJ; Jacob, S; Kinnick, TR; Schmit, MB; Youngblood, EB | 1 |
| Foss, MC; Gallo Júnior, L; Gouveia, LM; Reis, ML; Rothschild, AM; Tumilero, S | 1 |
| Mikkelsen, EO; Simonsen, U; Tankó, LB | 1 |
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| Saikawa, T; Sakata, T; Yasunaga, S; Yonemochi, H | 1 |
| Boels, PJ; Deutsch, J; Gao, B; Haworth, SG | 1 |
| Somlev, B; Subev, M | 1 |
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| Kaarto, H; Korhonen, H; Korpela, R; Nurminen, ML; Pihlanto-Leppälä, A; Piilola, K; Sipola, M; Tossavainen, O; Vapaatalo, H | 1 |
| Bonaria Salis, M; Capogrossi, MC; Chao, J; Chao, L; Emanueli, C; Figueroa, C; Gaspa, L; Madeddu, P | 1 |
| Arbin, V; Claperon, N; Fournié-Zaluski, MC; Peyroux, J; Roques, BP | 1 |
| Capella, MM; Juliano, L; Lima, AP; Morandi, V; Morrot, A; Müller-Esterl, W; Scharfstein, J; Schmitz, V | 1 |
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| Danser, AH; de Vries, R; Saxena, PR; Tom, B | 1 |
| Adam, A; Bachvarov, DR; Bouthillier, J; Guay, K; Houle, S; Marceau, F; Sabourin, T | 1 |
| Hayashi, I; Ishihara, K; Kumagai, Y; Majima, M | 1 |
| Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG | 1 |
| Damas, J; Hallet, C; Lefebvre, PJ | 1 |
| Johnston, GD; Maguire, SM; McAuley, D; McGurk, C; Nicholls, DP; Nugent, AG | 1 |
| Abe, I; Fujii, K; Goto, K; Kansui, Y | 1 |
| de Gasparo, M; Feng, TC; Hua, RJ; Ji, YY; Ying, WY | 1 |
| Imamura, T; Ishikawa, T; Nakayama, K; Nejishima, H | 1 |
| Blais, PA; Gobeil, F; Hallé, S; Regoli, D | 1 |
| Diamond, LE; Logan, JS; McGregor, CG; Miller, VM; Severson, SR; Taner, CB; Ugurlu, MM; Warnecke, G | 1 |
| Miyamoto, A; Murata, S; Nishio, A | 1 |
| Hao, Y; Mineshita, S; Okamura, S; Wang, LM | 1 |
| Cuttle, G; Dovichi, SS; Häckl, LP; Lima-Landman, MT; Nicolau, M | 1 |
| Holstein-Rathlou, NH; Leong, PK; McDonough, AA; Yang, LE; Zhang, Y | 1 |
| Brzoska, T; Luger, TA; Riemann, H; Scholzen, TE; Ständer, S | 1 |
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| Cahová, M; Kazdova, L; Meschisvilli, E; Tutterova, M; Vavrinková, H | 1 |
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| Chichorro, JG; Lorenzetti, BB; Zampronio, AR | 1 |
| Campagnole-Santos, MJ; de Carvalho, MH; Fernandes, L; Maia, LG; Ramos, MC; Souza dos Santos, RA | 1 |
| Cadnapaphornchai, MA; Chen, YC; Gera, L; Rogachev, B; Schrier, RW; Stewart, JM; Summer, SN | 1 |
| Kojima, F; Naraba, H; Narumiya, S; Oh-ishi, S; Ueno, A; Ushikubi, F; Yuhki, K | 1 |
| de Moura, RS; Pimentel, AM; Resende, AC | 1 |
| Batenburg, WW; Danser, AH; de Bruijn, RJ; de Vries, R; Dive, V; Georgiadis, D; Tom, B; van Esch, JH; van Gool, JM; Yiotakis, A | 1 |
| Abbas, SA; Sharma, JN | 2 |
| Gao, XY; Wang, HJ; Wang, W; Zhang, F; Zhang, Y; Zhu, GQ | 1 |
| Alves, MF; Aparecida Juliano, M; Araujo, MS; Barros, NM; Carmona, AK; Juliano, L; Puzer, L; Reis, ML; Vercesi, J | 1 |
| Damas, J; Garbacki, N; Lefèbvre, PJ | 1 |
| Hilgenfeldt, U; Lewicka, S; Liu, X; Lukasova, M; Zubakova, R | 1 |
| Averbukh, Z; Berman, S; Cohn, M; Efrati, S; Modai, D; Rapoport, M; Weissgarten, J | 1 |
| Daray, FM; Errasti, AE; Falcioni, AG; Gago, JE; Goldschmidt, ED; Nowak, W; Pelorosso, FG; Pugliese, MI; Rothlin, RP | 1 |
| Bos, AP; Florquin, S; Haitsma, JJ; Lachmann, B; Lutter, R; Merkus, MP; van der Loos, CM; van Woensel, JB; Wösten-van Asperen, RM | 1 |
| Cocks, TM; Drummond, GR; Selemidis, S | 1 |
| Montenegro, MF; Pessa, LR; Tanus-Santos, JE | 1 |
| Campos, RR; Carillo, BA; Couto, GK; Prezoto, BC; Rossoni, LV; Schoorlemmer, GH | 1 |
| Fukuda, K; Hirooka, K; Itano, T; Mizote, M; Nakamura, T; Shiraga, F | 1 |
| Dias-Junior, CA; Kanashiro, A; Montenegro, MF; Neto-Neves, EM; Spiller, F; Tanus-Santos, JE | 1 |
| Blair, AE; Broadley, KJ; Bugert, JJ; Ford, WR; Kidd, EJ | 1 |
| Cialdai, C; Giuliani, S; Maggi, CA; Tramontana, M; Valenti, C | 1 |
| Bongianni, F; Cinelli, E; Evangelista, S; Mutolo, D; Pantaleo, T | 1 |
| Ehlers, PI; Korpela, R; Nurmi, L; Turpeinen, AM; Vapaatalo, H | 1 |
| Camargo, AC; Guerreiro, JR; Ianzer, D; Serrano, SM | 1 |
| Chaves, MM; Chianca-Júnior, D; Costa, DC; Granato de Faria, K; Lima, WG; Pádua, Bda C; Pedrosa, ML; Rodrigues de Araujo, G; Rossoni, JV; Silva, ME; Souza, AA | 1 |
| Doris, PA; Mamenko, M; Pochynyuk, O; Zaika, O | 1 |
| Bagi, Z; Cassuto, J; Feher, A; Patel, V; Szabo, A; Vinayak Kamath, M | 1 |
| Campbell, WB; Cepura, CJ; Gauthier, KM | 1 |
| Brouwers, S; Dupont, AG; Massie, A; Smolders, I | 1 |
| Barba de la Rosa, AP; Estrada-Salas, PA; González, C; Martínez-Cuevas, PP; Montero-Morán, GM | 1 |
| Ferrario, CM; Flores-Monroy, J; Hernández-Campos, ME; Martínez-Aguilar, L; Valencia-Hernández, I | 1 |
| Liu, JX; Wang, L; Zhang, Y | 1 |
| Chong, I; Edward, JA; Feintech, SV; Jones, MR; Jupiter, RC; Kadowitz, PJ; Lasker, GF; Lindsey, SH; Pankey, EA; Peak, TC; Reddy, VG; Yoo, D | 1 |
| Laraba-Djebari, F; Martin-Eauclaire, MF; Medjadba, W | 1 |
| André, E; Brusco, I; Cabrini, DA; de Oliveira, JR; Ferreira, J; Oliveira, SM; Otuki, MF | 1 |
| Korpela, R; Siltari, A; Vapaatalo, H | 1 |
| Audi, EA; Gama, VS; Graeff, FG; Maraschin, JC; Sestile, CC; Zangrossi, H | 1 |
| Korpela, R; Roivanen, J; Siltari, A; Vapaatalo, H | 1 |
| Hu, Y; Jiang, T; Jiang, X; Jin, K; Luo, Z; Mei, H; Pang, Z; Shi, W; Tuo, Y; Zhang, B | 1 |
| Albuquerque, AA; Capellini, VK; Carvalho, MTM; Celotto, AC; Evora, PRB; Ferreira, LG; Gomes, RADS; Parolini, MT | 1 |
| Cao, Y; Chen, JG; Deng, SL; Han, QQ; He, JG; Hu, ZL; Huang, JG; Jin, M; Long, LH; Luo, H; Ni, L; Shen, TT; Wang, F; Wang, J; Wu, PF | 1 |
| Kini, RM; Koh, CY | 1 |
9 review(s) available for captopril and bradykinin
| Article | Year |
|---|---|
Effects of converting-enzyme inhibitors on the renin-angiotensin-aldosterone, bradykinin, and arachidonic acid-prostaglandin systems: correlation of chemical structure and biologic activity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bradykinin; Captopril; Enalapril; Humans; Prostaglandins; Renin-Angiotensin System; Structure-Activity Relationship | 1987 |
[Pharmacological effects of captopril].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Cats; Disease Models, Animal; Dogs; Hemodynamics; Humans; Hypertension; Mice; Proline; Rabbits; Rats; Renin | 1981 |
Inhibitors of the angiotensin I converting enzyme as antihypertensive drugs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Captopril; Dipeptides; Drug Interactions; Enalapril; Hemodynamics; Humans; Kallikreins; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Vasodilator Agents | 1983 |
Mechanisms of the antihypertensive action of captopril.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Bradykinin; Brain; Captopril; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Proline; Prostaglandins; Rats; Rats, Inbred SHR; Renal Circulation; Renin-Angiotensin System | 1984 |
Captopril--indications and clinical problems.
Topics: Animals; Blood Pressure; Bradykinin; Brain; Captopril; Cats; Dogs; Female; Guinea Pigs; Haplorhini; Heart Failure; Humans; Hypertension; Kallikreins; Kinetics; Pregnancy; Proline; Prostaglandins; Rabbits; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Scleroderma, Systemic | 1984 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Dogs; Hemodynamics; Hydralazine; Hydrochlorothiazide; Hypertension; Kallikreins; Kidney; Proline; Prostaglandins; Rabbits; Rats; Renin; Sodium | 1980 |
Angiotensin converting enzyme (ACE) inhibitors and kinin metabolism: evidence that ACE inhibitors may inhibit a kininase other than ACE.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Humans; Kinins | 1995 |
Bradykinin-potentiating peptides: beyond captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Argininosuccinate Synthase; Blood Pressure; Bothrops; Bradykinin; Captopril; Cardiovascular System; Crotalid Venoms; Humans; Hypertension; Proline; Vasodilator Agents | 2012 |
Snake venom three-finger toxins and their potential in drug development targeting cardiovascular diseases.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cardiovascular Diseases; Drug Development; Humans; Peptides; Snake Venoms; Toxins, Biological | 2020 |
19 trial(s) available for captopril and bradykinin
| Article | Year |
|---|---|
Long-term effects of captopril (SQ14 225) on blood-pressure and hormone levels in essential hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Proline; Renin | 1979 |
Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Proline; Renin | 1979 |
Cough induced by ACE-inhibitors. A kinin related phenomenon?
Topics: Adult; Asthma; Bradykinin; Captopril; Cough; Double-Blind Method; Histamine; Humans; Hypertension | 1992 |
Airway responsiveness and cough induced by angiotensin converting enzyme inhibition.
Topics: Adult; Airway Resistance; Angiotensin-Converting Enzyme Inhibitors; Asthma; Bradykinin; Bronchi; Bronchial Provocation Tests; Captopril; Cough; Double-Blind Method; Histamine; Humans; Hypertension; Lung | 1992 |
Converting enzyme inhibitors and the role of the sulfhydryl group in the potentiation of exo- and endogenous nitrovasodilators.
Topics: Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Bradykinin; Captopril; Coronary Circulation; Cysteine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; Nitro Compounds; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasodilator Agents | 1991 |
Bradykinin-induced cough reflex markedly increases in patients with cough associated with captopril and enalapril.
Topics: Adult; Aerosols; Aged; Bradykinin; Captopril; Citrates; Citric Acid; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Reflex; Respiratory Function Tests; Substance P | 1991 |
Blood pressure control by the renin-angiotensin system in normotensive subjects. Assessment by angiotensin converting enzyme and renin inhibition.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Double-Blind Method; Hemodynamics; Humans; Imidazoles; Male; Reference Values; Renin; Renin-Angiotensin System | 1992 |
Effect of captopril on skin blood flow following intradermal bradykinin measured by laser Doppler flowmetry.
Topics: Adult; Bradykinin; Captopril; Dose-Response Relationship, Drug; Female; Humans; Injections, Intradermal; Male; Regional Blood Flow; Rheology; Skin; Skin Tests | 1989 |
Angiotensin-converting enzyme and the cough reflex.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cough; Female; Humans; Male; Peptidyl-Dipeptidase A; Placebos | 1987 |
Converting enzyme inhibition in mild and moderate essential hypertension. I. Acute effects on blood pressure, the renin-angiotensin system and blood bradykinin after a single dose of captopril.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1985 |
Converting enzyme inhibition in mild and moderate essential hypertension. II.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Plasma Volume; Renin-Angiotensin System; Sodium | 1986 |
Effects of intradermal bradykinin after inhibition of angiotensin converting enzyme.
Topics: Adult; Angioedema; Bradykinin; Captopril; Dose-Response Relationship, Drug; Enalapril; Humans; Middle Aged; Skin; Time Factors | 1987 |
Angiotensin II formation by an alternative pathway during exercise in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Benzamidines; Blood Pressure; Bradykinin; Captopril; Cross-Over Studies; Double-Blind Method; Exercise; Guanidines; Heart Rate; Humans; Lactates; Lactic Acid; Male; Peptidyl-Dipeptidase A; Renin; Serine Proteinase Inhibitors | 1994 |
Cutaneous blood flow changes and weal induced by intradermal bradykinin following pretreatment with indomethacin and captopril.
Topics: Bradykinin; Captopril; Double-Blind Method; Female; Humans; Indomethacin; Injections, Intradermal; Laser-Doppler Flowmetry; Male; Premedication; Regional Blood Flow; Skin | 1993 |
A comparison of the effects of captopril and enalapril on skin responses to intradermal bradykinin and skin blood flow in the human forearm.
Topics: Adult; Bradykinin; Captopril; Double-Blind Method; Enalapril; Female; Forearm; Humans; Laser-Doppler Flowmetry; Male; Regional Blood Flow; Skin | 1993 |
Determination of bradykinin-(1-5) in inflammatory exudate by a new ELISA as a reliable indicator of bradykinin generation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibody Specificity; Bradykinin; Bromelains; Calibration; Captopril; Carrageenan; Dexamethasone; Enzyme-Linked Immunosorbent Assay; Exudates and Transudates; Humans; Male; Pleurisy; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity | 1996 |
Selective stimulation of tissue-type plasminogen activator (t-PA) in vivo by infusion of bradykinin.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Female; Humans; Hypertension; Isoquinolines; Male; Plasminogen Activator Inhibitor 1; Quinapril; Randomized Controlled Trials as Topic; Tetrahydroisoquinolines; Tissue Plasminogen Activator | 1997 |
Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diet, Sodium-Restricted; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney; Losartan; Male; Reference Values; Renin-Angiotensin System; Single-Blind Method | 1998 |
Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity.
Topics: Aged; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Bradykinin; Captopril; Coronary Vessels; Endothelium, Vascular; Female; Gene Expression Regulation, Enzymologic; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2013 |
366 other study(ies) available for captopril and bradykinin
| Article | Year |
|---|---|
Mechanism of the protective effect of angiotensin-converting enzyme inhibition in hemorrhagic shock.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cats; Male; Mesenteric Arteries; Proline; Regional Blood Flow; Shock, Hemorrhagic | 1979 |
Potentiation of the algogenic action of bradykinin by an inhibitor of angiotensin I converting enzyme, captopril (SQ 14,225).
Topics: Acetylcholine; Animals; Bradykinin; Captopril; Dogs; Drug Synergism; Female; Femoral Artery; Injections, Intra-Arterial; Male; Mesenteric Arteries; Pain; Peptidyl-Dipeptidase A; Proline; Vocalization, Animal | 1979 |
The effects of captopril (SQ 14,225) on bradykinin-induced bronchoconstriction in the anesthetized guinea pig.
Topics: Airway Resistance; Animals; Bradykinin; Bronchial Spasm; Captopril; Drug Synergism; Guinea Pigs; Hemodynamics; In Vitro Techniques; Lung; Lung Compliance; Male; Proline; Propranolol; Time Factors | 1979 |
Central and peripheral effects of bradykinin and prostaglandin E2 on blood pressure in conscious rats.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Indomethacin; Injections, Intravenous; Injections, Intraventricular; Male; Prostaglandins E; Rats; Time Factors | 1979 |
SQ 14,225 attenuates the vascular response to norepinephrine in the rat mesenteric arteries.
Topics: Angiotensin II; Animals; Bradykinin; Captopril; Drug Interactions; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Perfusion; Pressure; Proline; Rats; Teprotide | 1979 |
Responses of the renin-angiotensin system and kallikrein-kinin system to sodium and converting enzyme inhibitor (SQ 14,225).
Topics: Angiotensin I; Angiotensins; Animals; Bradykinin; Captopril; Diet; Kallikreins; Kinins; Male; Proline; Rats; Renin; Sodium | 1979 |
Local potentiation of bradykinin-induced vasodilation by converting-enzyme inhibition in isolated coronary arteries.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Bradykinin; Captopril; Cattle; Coronary Vessels; Dipeptides; Enalaprilat; Endothelium, Vascular; Fosinopril; Humans; In Vitro Techniques; Lisinopril; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Ramipril; Receptors, Bradykinin; Receptors, Neurotransmitter; Vasodilation; Vasodilator Agents | 1992 |
Role of peptidases in bradykinin-induced increase in vascular permeability in vivo.
Topics: Animals; Bradykinin; Capillary Permeability; Captopril; Cheek; Cricetinae; Glycopeptides; Inflammation; Microcirculation; Neprilysin; Peptidyl-Dipeptidase A; Thiorphan | 1992 |
Effects of converting enzyme inhibition on endothelial bradykinin metabolism and endothelium-dependent vascular relaxation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cattle; Cells, Cultured; Coronary Vessels; Dipeptides; Enalaprilat; Endothelium, Vascular; Humans; In Vitro Techniques; Isometric Contraction; Kinetics; Lisinopril; Vasodilation | 1992 |
Converting enzyme inhibitor-stimulated formation of nitric oxide and prostacyclin in endothelial cells from bovine aorta is mediated by endothelium-derived bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arginine; Bradykinin; Captopril; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Nitric Oxide; Nitroarginine; Ramipril | 1992 |
Influence of a kinin antagonist on acute hypotensive responses induced by bradykinin and captopril in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Fluoroacetates; Heart Rate; Hypotension; Injections, Intravenous; Models, Biological; Oligopeptides; Rats; Rats, Inbred SHR; Receptors, Bradykinin; Receptors, Neurotransmitter; Time Factors | 1992 |
Effect of resiniferatoxin on the isolated rabbit iris sphincter muscle: comparison with capsaicin and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Captopril; Diterpenes; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Rabbits; Substance P; Tachykinins; Tachyphylaxis; Thiorphan | 1992 |
Cardioprotection of ACE inhibitor in ischemic heart is not dependent on the local angiotensin II formation.
Topics: Angiotensin II; Animals; Benzamidines; Blood Pressure; Bradykinin; Captopril; Cardiac Output; Coronary Circulation; Coronary Vessels; Dogs; Guanidines; Heart; Hemodynamics; Kallikreins; Male; Myocardial Infarction; Myocardium; Vascular Resistance | 1992 |
Increase in the kinin levels in the bronchial washings after intravenous injection of leukotriene C4 in guinea pigs.
Topics: 3-Mercaptopropionic Acid; Amino Acid Sequence; Animals; Biotransformation; Bradykinin; Bronchoalveolar Lavage Fluid; Captopril; Guinea Pigs; Injections, Intravenous; Kinins; Lysine Carboxypeptidase; Male; Mercaptoethanol; Molecular Sequence Data; SRS-A | 1992 |
Involvement of nitric oxide in the regional haemodynamic effects of perindoprilat and captopril in hypovolaemic Brattleboro rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Benzopyrans; Blood Volume; Bradykinin; Captopril; Cromakalim; Hemodynamics; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrroles; Random Allocation; Rats; Rats, Brattleboro; Vasodilation; Vasodilator Agents | 1992 |
A stable metabolite, Arg-Pro-Pro-Gly-Phe, of bradykinin in the degradation pathway in human plasma.
Topics: Adult; Amino Acid Sequence; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Half-Life; Humans; Male; Molecular Sequence Data; Oligopeptides; Peptide Fragments | 1992 |
Converting-enzyme inhibitors potentiate bradykinin-induced relaxation in vitro.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Dinoprost; Drug Synergism; Endothelium, Vascular; Femoral Artery; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Swine | 1992 |
A new bradykinin-potentiating peptide (peptide P) isolated from the venom of Bothrops jararacussu (jararacuçu tapete, urutu dourado).
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Chromatography, Gel; Chromatography, High Pressure Liquid; Crotalid Venoms; Drug Synergism; Female; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Oligopeptides; Organ Culture Techniques; Rats; Snakes | 1992 |
Effect of an angiotensin II and a kinin receptor antagonist on the renal hemodynamic response to captopril.
Topics: Angiotensin II; Animals; Bradykinin; Captopril; Hemodynamics; Imidazoles; Kinins; Lasers; Losartan; Punctures; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter; Renal Circulation; Tetrazoles; Ultrasonography | 1991 |
[Are the radical scavenging properties of ACE inhibitors with sulfhydryl groups in therapeutically effective concentrations of quantitative significance?].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bridged Bicyclo Compounds; Captopril; Coronary Disease; Dose-Response Relationship, Drug; Enalapril; Guinea Pigs; Hemodynamics; Hydroxides; Hydroxyl Radical; Luminescent Measurements; Myocardial Reperfusion Injury; Pyrroles; Ramipril; Sulfhydryl Reagents; Uric Acid | 1991 |
Metabolism of bradykinin agonists and antagonists by plasma aminopeptidase P.
Topics: 3-Mercaptopropionic Acid; Aminopeptidases; Animals; Bradykinin; Captopril; Hydrogen-Ion Concentration; Hydrolysis; Kallidin; Kinetics; Kinins; Lysine Carboxypeptidase; Peptidyl-Dipeptidase A; Rats | 1991 |
Angiotensin converting enzyme inhibitors potentiate the bronchoconstriction induced by substance P in the guinea-pig.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bronchi; Capsaicin; Captopril; Drug Synergism; Enalaprilat; Guinea Pigs; In Vitro Techniques; Male; Neuropeptides; Prazosin; Serotonin; Substance P | 1990 |
Hemodynamic effects of bradykinin on systemic and pulmonary circulation in healthy and hypertensive humans.
Topics: Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Cardiac Output; Enalapril; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Lisinopril; Male; Middle Aged; Pulmonary Circulation; Vascular Resistance | 1990 |
Enhanced contractility of the rat stomach during suppression of angiotensin converting enzyme by captopril in vitro.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Atropine; Bradykinin; Captopril; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Peptidyl-Dipeptidase A; Pressure; Rats; Saralasin; Stomach; Tetrodotoxin | 1991 |
Effect of bradykinin on isolated mesenteric arteries of the rat.
Topics: Animals; Bradykinin; Captopril; Drug Synergism; Indomethacin; Male; Mesenteric Arteries; Prostaglandins; Rats; Rats, Inbred Strains; Time Factors; Vasodilation | 1992 |
Bradykinin-induced airway microvascular leakage is potentiated by captopril and phosphoramidon.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Glycopeptides; Guinea Pigs; Lung; Neprilysin; Time Factors | 1991 |
Evidence for a role of bradykinin in experimental pain models.
Topics: Animals; Benzoquinones; Bradykinin; Captopril; Disease Models, Animal; Female; Male; Mice; Mice, Inbred Strains; Pain; Pain Measurement; Phenanthrolines; Rats | 1991 |
The potentiation of cardiodepressant and hypotensive effects of bradykinin by enalapril and captopril both in vitro and in vivo.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enalapril; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Isometric Contraction; Male | 1991 |
Kinin contribution to renal vasodilator effect of captopril in rabbit.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Captopril; Imidazoles; Kidney; Losartan; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter; Renal Circulation; Saralasin; Tetrazoles; Vasodilation | 1991 |
Interaction of bradykinin and angiotensin in the regulation of blood pressure in conscious rats.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Drug Interactions; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Saralasin | 1991 |
Bradykinin-induced dipsogenesis in captopril-treated rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Bradykinin; Captopril; Drinking; Male; Rats; Rats, Inbred Strains; Thirst | 1991 |
Bradykinin release from contracting skeletal muscle of the cat.
Topics: Animals; Arteries; Blood Gas Analysis; Bradykinin; Captopril; Carbon Dioxide; Cats; Female; Hindlimb; Hydrogen-Ion Concentration; Lactates; Male; Muscle Contraction; Muscles; Oxygen; Radioimmunoassay; Regional Blood Flow | 1990 |
Interaction of ANP and bradykinin during endopeptidase 24.11 inhibition: renal effects.
Topics: Animals; Atrial Natriuretic Factor; Bradykinin; Captopril; Diuretics; Drug Synergism; Kidney; Male; Natriuresis; Neprilysin; Peptide Fragments; Rats; Rats, Inbred Strains; Thiorphan | 1990 |
Converting enzyme inhibition and vascular prostacyclin synthesis: effect of kinin receptor antagonism.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Eicosanoids; Enalapril; Epoprostenol; Female; In Vitro Techniques; Lisinopril; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter | 1990 |
Demonstration of extrapulmonary activity of angiotensin converting enzyme in intact tissue preparations.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Endothelium, Vascular; Female; Guinea Pigs; Ileum; In Vitro Techniques; Lung; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Inbred Strains; Uterine Contraction; Vasoconstriction | 1990 |
Pharmacological properties of the new non-sulfhydryl angiotensin converting enzyme inhibitor N-[8-amino-1(S)-carboxyoctyl]-L-alanyl-L-proline.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dipeptides; Enalapril; Enalaprilat; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Inbred WKY | 1990 |
The effects of bradykinin and the ischemic isolated rat heart.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Circulation; Coronary Disease; Coronary Vessels; Enalaprilat; Indomethacin; Myocardium; Rats; Vasodilation | 1990 |
Vascular effects of kinins in trout and bradykinin metabolism by perfused gill.
Topics: Animals; Blood Pressure; Blood Vessels; Bradykinin; Captopril; Carbon; Gills; Hydrogen; In Vitro Techniques; Ions; Kallikreins; Kinins; Perfusion; Salmonidae; Trout | 1990 |
The brain kallikrein-kinin system. A possible role in blood pressure regulation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Brain; Captopril; Injections, Intraventricular; Kallikreins; Kinins; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
Studies of the mechanism of angiotensin-converting enzyme (ACE) inhibitor-associated angioedema: the effect of an ACE inhibitor on cutaneous responses to bradykinin, codeine, and histamine.
Topics: Adult; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Blood Vessels; Bradykinin; Captopril; Codeine; Histamine; Humans; Hypersensitivity, Immediate; Middle Aged; Skin | 1990 |
Synthesis and pharmacological screening of new angiotensin converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Availability; Blood Pressure; Bradykinin; Captopril; Chemical Phenomena; Chemistry; Enalapril; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains | 1990 |
Components of the angiotensin system cause release of a neutrophil chemoattractant from cultured bovine and human endothelial cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Bradykinin; Captopril; Cattle; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Endothelium, Vascular; Humans; In Vitro Techniques; Interleukin-8; Neutrophils; Pulmonary Artery; Renin-Angiotensin System; Saralasin; Umbilical Veins | 1990 |
Inhibitory effects of kinins on angiotensin I conversion in the local circulation.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Hindlimb; Hydrolysis; Kinetics; Kinins; Male; Perfusion; Rats; Rats, Inbred Strains | 1990 |
Enhanced reactivity to bradykinin, angiotensin I and the effect of captopril in the pulmonary vasculature of chronically hypoxic rats.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Chronic Disease; Dose-Response Relationship, Drug; Hypoxia; Male; Pulmonary Artery; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1990 |
The effect of peptidase inhibitors on bradykinin-induced bronchoconstriction in guinea-pigs in vivo.
Topics: 3-Mercaptopropionic Acid; Animals; Asthma; Bradykinin; Bronchoconstriction; Captopril; Glycopeptides; Guinea Pigs; In Vitro Techniques; Lysine Carboxypeptidase; Male; Muscle, Smooth; Propranolol; Protease Inhibitors | 1990 |
Hypotensive effect of captopril. Role of bradykinin and prostaglandinlike substances.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Drug Synergism; Female; Hypotension; Ileum; Indomethacin; Male; Muscle Tonus; Prostaglandins | 1990 |
Mechanisms of captopril-induced potentiation of the depressor responses to arachidonic acid in rats.
Topics: Angiotensin I; Animals; Antihypertensive Agents; Aprotinin; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Injections, Intra-Arterial; Injections, Intravenous; Male; Rats; Rats, Inbred Strains | 1986 |
Bradykinin in reflex cardiovascular responses to static muscular contraction.
Topics: Animals; Aprotinin; Bradykinin; Captopril; Carboxypeptidase B; Carboxypeptidases; Cardiovascular Physiological Phenomena; Cats; Female; Hindlimb; Male; Muscle Contraction; Muscles; Reflex | 1986 |
Analysis of influence of extra- and intrarenally formed angiotensin II on renal blood flow.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Male; Rabbits; Regional Blood Flow; Renal Circulation | 1986 |
Mechanisms for the inhibition of vasopressin-stimulated water flow by captopril in the toad bladder.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Body Water; Bradykinin; Bufo bufo; Captopril; Dinoprostone; In Vitro Techniques; Indomethacin; Prostaglandins E; Urinary Bladder; Urodynamics; Vasopressins | 1987 |
Rat paw edema induced by trimucase II, a kinin-releasing enzyme from Trimeresurus mucrosquamatus venom.
Topics: Animals; Aprotinin; Bradykinin; Captopril; Cellulose; Crotalid Venoms; Edema; Foot; Guinea Pigs; Ileum; In Vitro Techniques; Kinins; Muscle Contraction; Peptide Hydrolases; Rats; Rats, Inbred Strains | 1988 |
Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology.
Topics: Acute Kidney Injury; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Fosinopril; Heart Rate; Injections, Intravenous; Macaca fascicularis; Male; Organophosphorus Compounds; Proline; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Time Factors | 1989 |
Interaction of endogenous kinins and prostaglandins in the plasma exudation of kaolin-induced pleurisy in rats.
Topics: Animals; Bradykinin; Captopril; Exudates and Transudates; Histamine Release; Indomethacin; Kaolin; Kinins; Male; Pleurisy; Prostaglandins; Radioimmunoassay; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Significance of kallikrein-kinin and renin-angiotensin systems in the hypotensive mechanism of angiotensin-I converting enzyme inhibitors in essential hypertensives.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Captopril; Diuresis; Heart Rate; Humans; Hypertension; Kallikreins; Kinins; Ramipril; Renin-Angiotensin System | 1989 |
The effects of intradermal bradykinin are potentiated by angiotensin converting enzyme inhibitors in hypertensive patients.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Drug Synergism; Enalapril; Female; Humans; Hypertension; Injections, Intradermal; Male; Middle Aged; Skin | 1989 |
Kinin antagonist reverses converting enzyme inhibitor-stimulated vascular prostaglandin I2 synthesis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Bradykinin; Captopril; Enalapril; Enalaprilat; Epoprostenol; In Vitro Techniques; Kidney Cortex; Kinins; Male; Prostaglandins; Rats; Rats, Inbred Strains | 1989 |
Increased sensitivity to bradykinin in pregnant rats.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Female; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains | 1989 |
The increase in coronary flow induced by converting enzyme inhibitors is prostacyclin independent.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Circulation; Enalaprilat; Epoprostenol; In Vitro Techniques; Indomethacin; Male; Rats; Rats, Inbred Strains | 1989 |
Angiotensin converting enzyme inhibitors, captopril and enalaprilat, augment bradykinin-induced prostacyclin synthesis in cultured rat vascular smooth muscle cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Captopril; Cells, Cultured; Drug Synergism; Enalaprilat; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains | 1989 |
The haemodynamic effects of two angiotensin converting enzyme inhibitors, enalaprilat and zofenoprilat, in the rat: evidence for the involvement of bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Enalaprilat; Hemodynamics; Male; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter; Structure-Activity Relationship | 1989 |
Peripheral hemodynamic effects of captopril in patients with congestive heart failure.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Bradykinin; Captopril; Dinoprostone; Female; Forearm; Heart Failure; Hemodynamics; Humans; Indomethacin; Male; Middle Aged; Plethysmography; Regional Blood Flow; Renin-Angiotensin System | 1989 |
Role of endogenous bradykinins in the acute depressor effect of angiotensin converting enzyme inhibitor captopril--assessed by a competitive antagonist of bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Fluoroacetates; Male; Rats; Rats, Inbred Strains | 1989 |
Effects of the bradykinin antagonist B4310 on smooth muscles and blood pressure in the rat, and its enzymatic degradation.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Diethylstilbestrol; Duodenum; Female; In Vitro Techniques; Kallidin; Lung; Male; Muscle, Smooth; Rats; Rats, Inbred Strains; Uterus | 1989 |
[Severe hyponatremia associated with captopril therapy in dilated cardiomyopathy: a case report].
Topics: Bradykinin; Captopril; Cardiomyopathy, Dilated; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Prostaglandins | 1989 |
Role of high molecular weight (HMW)-kininogen in inflammatory exudation: evidence with the studies of the HMW-kininogen deficient rat.
Topics: Animals; Bradykinin; Capillary Permeability; Captopril; Edema; Guinea Pigs; Inflammation; Kininogens; Male; Pleurisy; Rabbits; Rats; Rats, Inbred BN; Rats, Inbred Strains; Skin | 1989 |
Measurement of des-Phe8-Arg9-bradykinin by enzyme-immunoassay--a useful parameter of plasma kinin release.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Enzyme-Linked Immunosorbent Assay; Histamine; Inflammation; Kinins; Lysine Carboxypeptidase; Male; Rats; Rats, Inbred Strains | 1989 |
Synergistic potentiation by captopril and propranolol of bradykinin-induced bronchoconstriction in the guinea-pig.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Biphenyl Compounds; Bradykinin; Bronchi; Captopril; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Propranolol; Prostaglandin Endoperoxides, Synthetic | 1989 |
Effects of teprotide, captopril and enalaprilat on arterial wall kininase and angiotensin converting activity.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Enalapril; Enalaprilat; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Teprotide | 1987 |
Role of renal endopeptidase 24.11 in kinin metabolism in vitro and in vivo.
Topics: 3-Mercaptopropionic Acid; Animals; Bradykinin; Captopril; Glycopeptides; Kidney; Kinins; Lysine Carboxypeptidase; Metalloendopeptidases; Natriuresis; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1987 |
Effects of angiotensin I converting enzyme (ACE) related substances upon the vascular prostacyclin generation.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Humans; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY | 1987 |
Cerebrovascular reactivity to angiotensin and angiotensin-converting enzyme activity in cerebrospinal fluid.
Topics: Angiotensin II; Animals; Bradykinin; Captopril; Cats; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Female; Male; Parietal Lobe; Peptidyl-Dipeptidase A; Vasoconstriction | 1988 |
Contribution of kininase II to the waning of vascular actions of bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Edema; Female; Lymph; Male; Peptidyl-Dipeptidase A; Phentolamine; Propranolol; Reference Values; Saralasin; Vasodilation | 1988 |
Nature of kininase activity in the exudate in kaolin-induced inflammation of the air pouch type in rats.
Topics: Animals; Bradykinin; Captopril; Carboxypeptidases; Exudates and Transudates; Immunoenzyme Techniques; Inflammation; Kaolin; Lysine Carboxypeptidase; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1988 |
Resistance to blockade by saralasin of effect of ACE inhibitors in conscious sodium-restricted dog.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Dogs; Enalapril; Enalaprilat; Female; Kidney; Male; Renal Circulation; Renin; Renin-Angiotensin System; Saralasin; Vascular Resistance | 1988 |
Effect of captopril on the bradykinin-induced release of prostacyclin from guinea-pig lungs and bovine aortic endothelial cells.
Topics: Angiotensin I; Animals; Aorta; Biological Factors; Bradykinin; Captopril; Cattle; Endothelium, Vascular; Epoprostenol; Guinea Pigs; In Vitro Techniques; Lung; Nitric Oxide; Peptidyl-Dipeptidase A | 1988 |
The effect of peptides on cerebrovascular resistance in cats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cats; Cerebral Arteries; Enkephalins; Morphine; Naloxone; Neurotensin; Peptides; Receptors, Bradykinin; Receptors, Neurotransmitter; Receptors, Opioid; Vascular Resistance | 1985 |
Conversion of kinins and their antagonists into B1 receptor activators and blockers in isolated vessels.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Animals; Blood Vessels; Bradykinin; Captopril; Dogs; Endothelium; In Vitro Techniques; Kinins; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter | 1986 |
Involvement of endopeptidase 24.15 in the inactivation of bradykinin by rat brain slices.
Topics: 4-Aminobenzoic Acid; Animals; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Dynorphins; Endopeptidases; Glycopeptides; Hypothalamus; Leucine; Male; Metalloendopeptidases; Neurotensin; Oligopeptides; para-Aminobenzoates; Peptide Fragments; Phenanthrolines; Rats; Rats, Inbred Strains | 1987 |
Kinin stimulation of renin release in isolated rat glomeruli.
Topics: Animals; Arterioles; Bradykinin; Buffers; Captopril; Culture Media; In Vitro Techniques; Kidney Glomerulus; Kinins; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin; Serum Albumin, Bovine; Time Factors | 1985 |
Kallikrein and kininases in ocular tissues.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aqueous Humor; Bradykinin; Captopril; Carboxypeptidases; Choroid; Ciliary Body; Endopeptidases; Eye; Iris; Kallikreins; Lysine Carboxypeptidase; Neprilysin; Peptidyl-Dipeptidase A; Retina; Swine | 1985 |
Direct hypotensive action of intravascular bradykinin in man.
Topics: Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heart Rate; Humans; Hyperaldosteronism; Hypertension; Peptidyl-Dipeptidase A; Propranolol; Sodium Chloride | 1985 |
Potent inhibition of angiotensin-converting enzyme by [des-Pro3]-bradykinin or "converstatin" in comparison with Captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Bradykinin; Captopril; Hydrogen-Ion Concentration; Kinetics; Lung; Rats | 1985 |
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin I; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Dinoprostone; Dogs; Hypertension; Hypertension, Renovascular; Kallikreins; Male; Peptidyl-Dipeptidase A; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Water-Electrolyte Balance | 1986 |
Antihypertensive substance in seeds of Areca catechu L.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Antihypertensive Agents; Areca; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Male; Plants, Medicinal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tannins | 1986 |
Inhibition of angiotensin-converting enzyme by des-Leu10-angiotensin I: a potential mechanism of endogenous angiotensin-converting enzyme regulation.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Bradykinin; Captopril; Humans; Kinetics; Lung; Peptidyl-Dipeptidase A; Rabbits | 1986 |
Possible involvement of angiotensin I-converting enzyme in the inactivation of bradykinin by intact macrophages.
Topics: Angiotensins; Animals; Bradykinin; Captopril; Cell Membrane; Cytosol; Edetic Acid; Endopeptidases; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Isoflurophate; Kinetics; Macrophages; Peptidyl-Dipeptidase A; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases | 1986 |
[Responses of plasma bradykinin and the renin angiotensin axis to angiotensin II in hyperthyroid patients].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Humans; Hyperthyroidism; Middle Aged; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1986 |
Urinary excretions of kininase I and kininase II activities in essential hypertension. A sensitive and simple method for its kinin-destroying capacity.
Topics: Adolescent; Adult; Aged; Bradykinin; Captopril; Carboxypeptidases; Edetic Acid; Female; Humans; Hypertension; Kallikreins; Kinins; Lysine Carboxypeptidase; Male; Middle Aged; Peptidyl-Dipeptidase A; Phenanthrolines | 1985 |
Prostacyclin generation by cultured human vascular endothelial cells with reference to angiotensin I-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Vessels; Bradykinin; Captopril; Cells, Cultured; Endothelium; Enzyme Activation; Epoprostenol; Humans; Peptidyl-Dipeptidase A | 1986 |
Converting enzyme activity of free airway cells.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Female; Guinea Pigs; Macrophages; Male; Peptidyl-Dipeptidase A; Protease Inhibitors; Pulmonary Alveoli | 1986 |
Angiotensin converting enzyme inhibitors in diabetes: experimental and human experience.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Bradykinin; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Kinins; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains | 1986 |
Specific binding and proteolytic inactivation of bradykinin by membrane vesicles from pig intestinal smooth muscle.
Topics: 5'-Nucleotidase; Animals; Binding Sites; Bradykinin; Captopril; Cell Membrane; Drug Interactions; Enalapril; Endopeptidases; Enzyme Repression; Glycopeptides; In Vitro Techniques; Muscle, Smooth; Nucleotidases; Phenanthrolines; Swine | 1986 |
Bradykinin potentiating peptides isolated from alpha-casein tryptic hydrolysate.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Caseins; Chromatography, Gel; Drug Synergism; Enalapril; Enalaprilat; Guinea Pigs; Trypsin | 1987 |
Studies of the effects of insulin, bradykinin, and captopril on blood glucose levels of alloxan-diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Bradykinin; Captopril; Diabetes Mellitus, Experimental; Insulin; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Swine | 1986 |
Regulation of prostacyclin generation by angiotensin converting enzyme related substances in cultured human vascular endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cells, Cultured; Endothelium; Epoprostenol; Humans; Peptidyl-Dipeptidase A | 1987 |
Metabolism of bradykinin and angiotensin I by human basilar artery and rabbit aorta.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Basilar Artery; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Lysine Carboxypeptidase; Male; Muscle, Smooth, Vascular; Phenanthrolines; Rabbits | 1987 |
Increase in vascular permeability of rat and guinea pig skin by T-kinin.
Topics: Alprostadil; Animals; Bradykinin; Capillary Permeability; Captopril; Colforsin; Dose-Response Relationship, Drug; Exudates and Transudates; Guinea Pigs; Rats; Rats, Inbred Strains; Skin | 1988 |
Bradykinin-potentiating activity of captopril disulphide dimer (SQ 14,551).
Topics: Anesthesia; Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Time Factors | 1988 |
Effects of a competitive antagonist of bradykinin on blood pressure and renal blood flow in anesthetized rats.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Fluoroacetates; Kidney; Rats; Rats, Inbred Strains | 1988 |
Involvement of the kinin-generating cascade in enhanced vascular permeability in tumor tissue.
Topics: Animals; Ascites; Bradykinin; Capillary Permeability; Captopril; Kinins; Lysine Carboxypeptidase; Neoplasms, Experimental; Rats; Serum Albumin, Bovine; Trypsin Inhibitors | 1988 |
Plasma kinin concentration in deoxycorticosterone-salt hypertension.
Topics: Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Desoxycorticosterone; Hypertension; Kinins; Male; Rats; Rats, Inbred Strains; Sodium Chloride; Veins | 1988 |
Lack of effect of captopril on preglomerular renal microvascular prostanoid biosynthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Captopril; Dinoprostone; Endothelium, Vascular; In Vitro Techniques; Kidney; Male; Microcirculation; Prostaglandins E; Rabbits | 1988 |
Barrel rotation in rats induced by intracerebroventricular bradykinin antagonists.
Topics: Animals; Atropine; Bradykinin; Captopril; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Motor Activity; Muscimol; Naloxone; Phenobarbital; Phenytoin; Posture; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
Role of bradykinin generating and degrading systems in the vascular permeability response induced with kaolin in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Captopril; Cross Reactions; Histamine; Indomethacin; Inflammation; Kaolin; Lysine Carboxypeptidase; Male; Rats; Rats, Inbred Strains; Serotonin; Trypsin Inhibitors | 1987 |
Bradykinin does not contribute to hypotension in early canine endotoxemia.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Hypotension; Receptors, Angiotensin; Shock, Septic | 1987 |
Lack of a role of circulating bradykinin in the blood pressure response to acute angiotensin converting enzyme inhibition in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Male; Rats; Rats, Inbred Strains | 1987 |
Effect of captopril on bradykinin inactivation by human foetal placental circulation.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Maternal-Fetal Exchange; Muscle Contraction; Placenta; Pregnancy; Time Factors; Vascular Resistance | 1986 |
Effects of captopril and bradykinin on arterial pressure in rats with mestranol-induced hypertension.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Female; Hypertension; Mestranol; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1986 |
Hypotensive effect of bradykinin in normotensives and patients with renovascular hypertension.
Topics: Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Humans; Hypertension, Renovascular; Reference Values | 1986 |
Thermally potentiated responses to algesic substances of visceral nociceptors.
Topics: Animals; Bradykinin; Captopril; Dogs; Hot Temperature; In Vitro Techniques; Male; Nociceptors; Pain; Saline Solution, Hypertonic; Testis | 1987 |
Temperature-dependent effects of the components of kallikrein-kinin system on sperm motility in vitro.
Topics: Bradykinin; Captopril; Drug Synergism; Humans; Kallikreins; Male; Phenanthrolines; Sperm Motility; Stimulation, Chemical; Temperature | 1987 |
Effect of intracoronary captopril on coronary blood flow and regional myocardial function in dogs.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Heart; Hemodynamics; Male; Proline | 1985 |
Bovine and human endothelial cell production of neutrophil chemoattractant activity in response to components of the angiotensin system.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Cattle; Cells, Cultured; Chemotaxis, Leukocyte; Diethylcarbamazine; Dose-Response Relationship, Drug; Endothelium; Humans; Indomethacin; Neutrophils; Saralasin | 1985 |
No role for prostaglandins and bradykinin in the autoregulation of renal blood flow.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bradykinin; Captopril; Dinoprostone; Dogs; Female; Homeostasis; Indomethacin; Kidney; Male; Prostaglandins; Prostaglandins E; Renal Circulation | 1985 |
Angiotensin I-converting enzyme in amniotic fluid.
Topics: Adult; Amniotic Fluid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Bradykinin; Captopril; Cross Reactions; Female; Humans; Hydrolysis; Immune Sera; In Vitro Techniques; Peptidyl-Dipeptidase A; Pregnancy; Radioimmunoassay; Renin | 1984 |
[The effect of alterations of the renin-angiotensin system and the sympathetic nervous system on plasma bradykinin concentration in patients with essential hypertension].
Topics: Adult; Age Factors; Blood Pressure; Bradykinin; Captopril; Furosemide; Humans; Hypertension; Middle Aged; Norepinephrine; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1984 |
[Role of bradykinin in hypotension induced by the active factor derived from factor XII].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Factor XII; Factor XIIa; Hypotension; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Saralasin | 1984 |
Biochemical monitoring of vasoactive peptides during angiotensin converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cross Reactions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Peptidyl-Dipeptidase A; Radioimmunoassay; Renin | 1983 |
Captopril lowers urinary kallikrein in hypertensive patients.
Topics: Aprotinin; Bradykinin; Captopril; Humans; Hypertension; Kallikreins; Proline | 1980 |
Effect of angiotensin-converting enzyme inhibition on circulating and local kinin levels.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dogs; Glomerular Filtration Rate; Kallikreins; Kidney; Kinins; Rats; Receptors, Bradykinin; Receptors, Cell Surface; Renal Circulation; Vasodilation | 1982 |
Decreased uterine bradykinin receptors during captopril infusion in rats.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Female; Muscle, Smooth; Proline; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Cell Surface; Uterus | 1982 |
Kininases and vascular responses to kinins.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Bradykinin; Captopril; Carboxypeptidases; Female; In Vitro Techniques; Kinins; Lysine Carboxypeptidase; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rabbits; Receptors, Bradykinin; Receptors, Cell Surface | 1982 |
Further evidence for the existence of two receptor sites for bradykinin responsible for the diphasic effect in the rat isolated duodenum.
Topics: Animals; Bradykinin; Captopril; Duodenum; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Peptides; Potassium; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter; Sodium-Potassium-Exchanging ATPase | 1984 |
Hypotensive effect of captopril and decreased rat uterine bradykinin receptors.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Female; Muscle, Smooth; Proline; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Uterus | 1984 |
Analysis of the mechanism of acute decrease of blood pressure induced by captopril (SQ 14,225) in dogs by the use of aprotinin, SAR1-ILE8-angiotensin II and indomethacin.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Animals; Aprotinin; Blood Pressure; Bradykinin; Captopril; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Indomethacin; Male; Proline | 1981 |
Renal response to angiotensin-converting enzyme inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dogs; Glomerular Filtration Rate; Heart Failure; Humans; Hypertension; Kinins; Rabbits; Rats; Renal Circulation; Renin-Angiotensin System; Saralasin; Sodium; Teprotide; Water-Electrolyte Balance | 1982 |
Enkephalinase inhibition relieves pain syndromes of central dysnociception (migraine and related headache).
Topics: Acute Disease; Adult; Animals; Aprotinin; Bradykinin; Captopril; Drug Therapy, Combination; Ergotamine; Female; Guinea Pigs; Headache; Humans; Hypertension; Male; Mice; Middle Aged; Migraine Disorders; Neprilysin; Pain; Phenylalanine; Proline; Protease Inhibitors | 1981 |
Kallikrein potentiation of angiotensin I-induced contraction on isolated mesenteric artery.
Topics: Angiotensin I; Angiotensins; Animals; Bradykinin; Captopril; Drug Synergism; Kallikreins; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Saralasin; Swine; Teprotide | 1983 |
Hormonal responses to angiotensin blockade. Comparison between receptor antagonism and converting enzyme inhibition.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin | 1980 |
Inhibitors of angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Blood Pressure; Bradykinin; Captopril; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Protease Inhibitors; Rabbits; Rats; Snake Venoms; Structure-Activity Relationship | 1980 |
Effects of angiotensin I converting enzyme inhibitor (SQ 14225) on control of aldosterone.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Female; Potassium; Proline; Rabbits; Renin | 1980 |
Converting enzyme inhibition during chronic angiotensin II infusion in rats: evidence against a non-angiotensin mechanism.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Glucose; Heart Rate; Male; Rats; Saralasin | 1980 |
Effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro and its ethyl ester (MK-421) on angiotensin converting enzyme in vitro and angiotensin I pressor responses in vivo.
Topics: Administration, Oral; Anesthesia; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Dipeptides; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Enalapril; Enalaprilat; Esterification; Female; Guinea Pigs; In Vitro Techniques; Male; Rats | 1981 |
Kallikrein, kinins and blood pressure - effects of angiotensin-converting enzyme inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Humans; Hypertension, Renal; Kallikreins; Kidney; Kinins; Proline; Renin; Saralasin | 1980 |
Metabolism of [3H]benzoyl-phenylalanyl-alanyl-proline by pulmonary angiotensin converting enzyme in vivo: effects of bradykinin, SQ 14225 or acute hypoxia.
Topics: Animals; Bradykinin; Captopril; Dogs; Female; Hypoxia; In Vitro Techniques; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Proline; Rabbits | 1981 |
Vasoactive peptides and hypertension: role of angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Humans; Hypertension; Hypertension, Renovascular; Peptidyl-Dipeptidase A; Renin | 1981 |
Angiotensin-converting enzyme inhibitors: pathogenic and therapeutic implications for arterial hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Humans; Hypertension; Proline; Renal Dialysis; Renin; Sodium | 1981 |
Converting enzyme inhibition and modulation of plasma renin activity with captopril in anesthetized rats.
Topics: Acetylcholine; Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Isoproterenol; Male; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Renin | 1981 |
Inhibition of vascular permeability changes in rats by captopril.
Topics: Animals; Bradykinin; Capillary Permeability; Captopril; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Edema; Male; Peptidyl-Dipeptidase A; Proline; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Skin; Thromboxane B2 | 1982 |
Angiotensin I converting enzyme of rat intestinal and vascular surface membrane.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Bradykinin; Captopril; Intestines; Male; Microscopy, Electron; Peptidyl-Dipeptidase A; Rats; Tissue Distribution | 1982 |
Comparison of angiotensin converting enzyme inhibitors captopril and MK421-diacid in guinea pig atria.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dipeptides; Enalapril; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Proline | 1982 |
Effect of converting enzyme inhibition on pulmonary edema after microembolization.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Pulmonary Circulation; Pulmonary Edema; Pulmonary Embolism; Vascular Resistance | 1982 |
Effects of kininase II inhibitors on the vasomotor response to bradykinin of feline intracranial and extracranial arteries in vitro and in situ.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Bradykinin; Captopril; Cats; Cerebral Arteries; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Pia Mater; Sublingual Gland; Vasomotor System | 1983 |
[Antihypertensive mechanism of oral angiotensin I converting enzyme inhibitor (captopril) in renin-independent essential hypertension].
Topics: Adult; Blood Pressure; Bradykinin; Captopril; Humans; Hypertension; Middle Aged; Peptidyl-Dipeptidase A; Proline; Renin | 1983 |
Effect of bradykinin on lung vascular permeability in sheep.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Capillary Permeability; Captopril; Propranolol; Pulmonary Circulation; Sheep; Time Factors | 1983 |
Responses of the kallikrein-kinin system to angiotensin converting enzyme inhibitors in the rat.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Dipeptides; Enalapril; Kallikreins; Kinins; Male; Muscle, Smooth, Vascular; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sulfhydryl Compounds; Thiazolidines; Vasopressins | 1984 |
Captopril in mild and moderate essential hypertension: physiological and biochemical monitoring.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Plasma Volume; Proline; Renin-Angiotensin System; Time Factors | 1983 |
Converting enzyme inhibition in the rat by captopril is accompanied by potentiation of carrageenin-induced inflammation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Carrageenan; Dinoprostone; Drug Synergism; Edema; Inflammation; Male; Pain; Proline; Prostaglandins E; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Acute effects of captopril on cardiopulmonary hemodynamics and renin-angiotensin-aldosterone and bradykinin profile in hypertension.
Topics: Adult; Aged; Benzothiadiazines; Blood Pressure; Bradykinin; Captopril; Coronary Circulation; Diuretics; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Proline; Pulmonary Circulation; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Vascular Resistance | 1983 |
Angiotensin II and bradykinin: interactions between two centrally active peptides.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Diuresis; Drinking; Drug Interactions; Heart Rate; Indomethacin; Male; Rats; Rats, Inbred Strains; Saralasin | 1983 |
[Hypotensive effects of angiotensin I converting enzyme inhibitor, and relationship between kallikrein-kinin system and renin-angiotensin-aldosterone system].
Topics: Adult; Bradykinin; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin-Angiotensin System | 1983 |
Effects of captopril and propanolol on bradykinin-induced changes in vascular pressures, lymph total protein concentration, and weight in canine forelimbs.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Dose-Response Relationship, Drug; Female; Forelimb; Lymph; Male; Organ Size; Proline; Propranolol; Proteins | 1983 |
Renal kinins and renal haemodynamics.
Topics: Animals; Bradykinin; Captopril; Dogs; Indomethacin; Kallikreins; Kidney; Kinins; Renal Artery; Renal Circulation; Time Factors | 1983 |
[Acute antihypertensive effect of captopril in hypertensive patients: with special reference to kallikrein-kinin system].
Topics: Adult; Aldosterone; Blood Pressure; Bradykinin; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Proline; Renin | 1983 |
[Plasma bradykinin concentration in patients with cardiovascular diseases].
Topics: Adult; Angina Pectoris; Blood Pressure; Blood Specimen Collection; Bradykinin; Captopril; Catecholamines; Cold Temperature; Heart Diseases; Humans; Hypertension; Male; Radioimmunoassay | 1983 |
Evidence for the role of kinins in the acute antihypertensive effect of captopril in low-renin hypertension.
Topics: Adult; Blood Pressure; Bradykinin; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Kinins; Male; Middle Aged; Proline; Renin | 1984 |
[Effect of angiotensin I converting enzyme inhibitor (captopril) on blood pressure and bradykinin in patients with excessive aldosterone secretion].
Topics: Adult; Blood Pressure; Bradykinin; Captopril; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Proline; Renin-Angiotensin System | 1984 |
Hypotensive effect of human factor XII active fragment in conscious normotensive rats: role of bradykinin.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Factor XII; Humans; Male; Peptide Fragments; Rats; Rats, Inbred Strains | 1984 |
Effect of captopril on pre-existing and aminonucleoside-induced proteinuria in spontaneously hypertensive rats.
Topics: Animals; Bradykinin; Captopril; Hypertension; Immune Complex Diseases; Kidney Glomerulus; Male; Potassium; Proline; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats; Renin; Sodium | 1981 |
Chronotropic effects of angiotensin I, angiotensin II, bradykinin and vasopressin in guinea pig atria.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Catecholamines; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Indomethacin; Male; Reserpine; Saralasin; Vasopressins | 1982 |
The disappearance rate of intraventricular bradykinin in the brain of the conscious rat.
Topics: Animals; Bradykinin; Brain; Captopril; Consciousness; Kinetics; Male; Phenanthrolines; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Potentiation of bradykinin-induced decrease of blood pressure in dogs by SO 14,551, the disulfide metabolite of captopril.
Topics: Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Disulfides; Dogs; Drug Synergism; Female; Male; Proline | 1982 |
Reversal of bradykinin-induced reflex tachycardia to bradycardia by captopril; evidence for prostacyclin involvement.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Captopril; Eledoisin; Epoprostenol; Heart Rate; Male; Nitroglycerin; Proline; Prostaglandins; Rabbits | 1982 |
Vasodepressor property of the converting enzyme inhibitor captopril (SQ 14 225): the role of factors other than renin-angiotensin blockade in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Disease Models, Animal; Female; Hypertension; Nephrectomy; Proline; Rats; Renin; Saralasin | 1980 |
Effects of captopril on bradykinin-induced, prostaglandin-mediated bronchoconstriction in the guinea pig.
Topics: Animals; Bradykinin; Captopril; Guinea Pigs; Lung; Male; Proline; Prostaglandins; Pulmonary Circulation | 1980 |
Plasma converting enzyme activity (C.E.A.): an index of plasma levels of captopril?
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Endopeptidases; Male; Proline; Rabbits | 1980 |
Angiotensin-induced release of prostacyclin from perfused organs.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Epoprostenol; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Mesenteric Arteries; Prostaglandins; Rabbits; Saralasin | 1980 |
Prostacyclin mediates the potentiated hypotensive effect of bradykinin following captopril treatment.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Epoprostenol; Female; Hemodynamics; Indomethacin; Kidney; Male; Proline; Prostaglandins; Regional Blood Flow | 1980 |
Effective use of captopril (angiotensin I-converting enzyme inhibitor) in severe childhood hypertension.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Child; Humans; Hypertension, Malignant; Proline; Renin | 1980 |
Single-dose captopril administration in DOCA/salt rats: reduction of hypotensive effect by indomethacin.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Desoxycorticosterone; Hypertension; Indomethacin; Injections, Intraperitoneal; Male; Proline; Prostaglandins; Rats; Renin; Sodium Chloride | 1980 |
Role of angiotensin II and bradykinin in the diuresis caused by stimulation of atrial receptors.
Topics: Angiotensin II; Animals; Bradykinin; Captopril; Diuresis; Dogs; Heart; Heart Atria; Malpighian Tubules; Mechanoreceptors; Reflex; Rhodnius | 1980 |
Pharmacological studies of kinins in venous smooth muscles.
Topics: 3-Mercaptopropionic Acid; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; In Vitro Techniques; Jugular Veins; Kinins; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Structure-Activity Relationship | 1981 |
Effect of the converting-enzyme inhibitor SQ 14 225 (captopril) in early one-kidney, one-clip hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Depression, Chemical; Dose-Response Relationship, Drug; Hypertension, Renal; Hypertension, Renovascular; Male; Nephrectomy; Proline; Rats; Renin | 1981 |
Acute effects of captopril on blood pressure and circulating hormone levels in salt-replete and depleted normal subjects and essential hypertensive patients.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Proline; Pulse; Renin; Sodium | 1981 |
Effect of the angiotensin-converting enzyme inhibitor, captopril, on development of renal hypertension in rats.
Topics: Angiotensin I; Animals; Blood Pressure; Body Weight; Bradykinin; Captopril; Drinking; Female; Hypertension, Renal; Organ Size; Proline; Rats | 1981 |
Studies on the mechanism of captopril induced hypotension in rats.
Topics: Angiotensin I; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Hypotension; Indomethacin; Male; Nephrectomy; Proline; Rats; Saralasin | 1981 |
Captopril attenuates adrenergic vasoconstriction in rat mesenteric arteries by angiotensin-dependent and -independent mechanisms.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Potassium Chloride; Proline; Rats; Saralasin; Vasoconstriction | 1981 |
Sodium intake and renal responses to captopril in normal man and in essential hypertension.
Topics: Adolescent; Adult; Angiotensin II; Bradykinin; Captopril; Diet, Sodium-Restricted; Humans; Hypertension; Kidney; Middle Aged; Proline; Renal Circulation; Renin; Sodium | 1981 |
Antihypertensive effect of the oral angiotensin I-converting enzyme inhibitor in long-term treatment of hypertensive patients.
Topics: Adult; Aged; Aldosterone; Bradykinin; Captopril; Female; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renovascular; Kidney Failure, Chronic; Male; Middle Aged; Potassium; Proline; Renin; Renin-Angiotensin System | 1981 |
Captopril attenuates pressor responses to norepinephrine and vasopressin through depletion of endogenous angiotensin II.
Topics: Adult; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Humans; Norepinephrine; Proline; Vasopressins | 1982 |
Effects of captopril (SQ 14225) on norepinephrine-induced vasoconstriction in the isolated perfused mesentery and hindquarters of the rat.
Topics: Animals; Bradykinin; Captopril; Hindlimb; Male; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Regional Blood Flow; Splanchnic Circulation; Vasoconstriction | 1982 |
Antihypertensive and renal effects of captopril in relation to renin activity and bradykinin-induced vasodilation.
Topics: Adult; Antihypertensive Agents; Bradykinin; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Nitroprusside; Proline; Renal Circulation; Renin-Angiotensin System; Vascular Resistance; Vasodilation | 1982 |
Inhibition by nicotine of the vasodilator effect of bradykinin: evidence for a prostacyclin-dependent mechanism.
Topics: Animals; Aspirin; Blood Pressure; Bradykinin; Captopril; Coronary Circulation; Drug Interactions; Epoprostenol; Female; Guinea Pigs; In Vitro Techniques; Male; Nicotine; Prostaglandins; Rabbits; Vasodilator Agents | 1982 |
Captopril-induced hypotension is inhibited by the bradykinin blocker HOE-140 in Na(+)-depleted marmosets.
Topics: Administration, Oral; Animals; Blood Pressure; Bradykinin; Callithrix; Captopril; Female; Hypotension; Injections, Subcutaneous; Male; Piperazines; Renin; Sodium; Thiazoles | 1995 |
Pharmacological characterization of rabbit corpus cavernosum relaxation mediated by the tissue kallikrein-kinin system.
Topics: Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; Aprotinin; Arginine; Bradykinin; Captopril; In Vitro Techniques; Kallikrein-Kinin System; Kallikreins; Male; Molecular Sequence Data; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Penis; Rabbits; Spider Venoms | 1994 |
Desulfated hirugen (hirudin 54-65) induces endothelium-dependent relaxation of porcine pulmonary arteries.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Arginine; Atropine; Bradykinin; Calcium; Captopril; Cyclic GMP; Dinoprost; Endothelium, Vascular; Hirudins; Histamine; Indomethacin; Ketanserin; Methiothepin; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptide Fragments; Phentolamine; Pulmonary Artery; Swine; Vasodilation | 1994 |
Enhancement of left ventricular relaxation in the isolated heart by an angiotensin-converting enzyme inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Ventricular Function; Ventricular Function, Left | 1995 |
Characterization of kinin receptors modulating neurogenic contractions of the mouse isolated vas deferens.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Electric Stimulation; Male; Mice; Muscle Contraction; Muscle, Smooth; Receptors, Bradykinin; Synaptic Transmission; Vas Deferens | 1995 |
Role of angiotensin converting enzyme in the vascular effects of an endopeptidase 24.15 inhibitor.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Blood Pressure; Bradykinin; Captopril; Evaluation Studies as Topic; Hemodynamics; Male; Metalloendopeptidases; Molecular Sequence Data; Oligopeptides; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1995 |
Anaphylactoid reactions during haemodialysis in sheep are associated with bradykinin release.
Topics: Acrylic Resins; Acrylonitrile; Anaphylaxis; Animals; Bradykinin; Captopril; Disease Models, Animal; Female; Hemodynamics; Male; Membranes, Artificial; Radioimmunoassay; Renal Dialysis; Sheep | 1995 |
Effects of captopril on the human foetal placental circulation: an interaction with bradykinin and angiotensin I.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Indomethacin; Placenta; Placental Function Tests; Pregnancy; Prostaglandins; Regional Blood Flow; Vasoconstriction | 1995 |
Bradykinin-induced water intake and brain fos-like immunoreactivity in rats.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Brain; Captopril; Drinking; Enalapril; Male; Proto-Oncogene Proteins c-fos; Rats; Renin | 1995 |
Role of neutral endopeptidase in bronchial hyperresponsiveness to bradykinin induced by IL-1 beta.
Topics: Administration, Inhalation; Animals; Bradykinin; Bronchi; Bronchoalveolar Lavage Fluid; Captopril; Drug Synergism; Glycopeptides; Interleukin-1; Male; Neprilysin; Rats; Recombinant Proteins; Respiratory Hypersensitivity | 1995 |
Substrate- and inhibitor-specificity of a non-endothelial enzyme which forms [Met5]-enkephalin from [Met5]-enkephalin-Arg6,Phe7 in isolated rabbit ear artery: pharmacological characterization.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Arteries; Bradykinin; Captopril; Disease Models, Animal; Ear, External; Enalapril; Endopeptidases; Endothelium, Vascular; Enkephalin, Methionine; Male; Migraine Disorders; Molecular Sequence Data; Rabbits; Substrate Specificity; Thiorphan | 1995 |
Endogenous BK stimulates ischemically sensitive abdominal visceral C fiber afferents through kinin B2 receptors.
Topics: Afferent Pathways; Animals; Aspirin; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cats; Ischemia; Nerve Fibers; Oligopeptides; Portal Vein; Receptors, Bradykinin; Viscera | 1994 |
Protective role of bradykinin in cardiac anaphylaxis. Coronary-vasodilating and antiarrhythmic activities mediated by autocrine/paracrine mechanisms.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Bradykinin; Captopril; Coronary Vessels; Cyclic GMP; Epoprostenol; Guinea Pigs; Male; Nitric Oxide; Vasodilation | 1995 |
Captopril increases skin microvascular blood flow secondary to bradykinin, nitric oxide, and prostaglandins.
Topics: Adult; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Humans; Male; Nitric Oxide; Prostaglandins; Rabbits; Regional Blood Flow; Skin | 1995 |
Prevention with icatibant of anaphylactoid reactions to ACE inhibitor during LDL apheresis.
Topics: Adrenergic beta-Antagonists; Anaphylaxis; Blood Component Removal; Bradykinin; Captopril; Child; Female; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL | 1994 |
Development of digoxigenin-labeled peptide: application to chemiluminoenzyme immunoassay of bradykinin in inflamed tissues.
Topics: 3-Mercaptopropionic Acid; Acute Disease; Amino Acid Sequence; Animals; Bradykinin; Captopril; Digoxigenin; Disease Models, Animal; Immunoenzyme Techniques; Inflammation; Luminescent Measurements; Lysine Carboxypeptidase; Male; Molecular Sequence Data; Molecular Structure; Rats; Rats, Wistar | 1994 |
Lack of involvement of the kallikrein-kinin system in the depressor effect of alpha-methyldopa in normotensive rats.
Topics: Animals; Blood Pressure; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Guinea Pigs; Kallikreins; Kininogens; Kinins; Male; Methyldopa; Rats; Rats, Wistar | 1994 |
Effects of bradykinin receptor agonists, and captopril and thiorphan in ferret isolated trachea: evidence for bradykinin generation in vitro.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Ferrets; In Vitro Techniques; Male; Muscle Contraction; Receptors, Bradykinin; Thiorphan; Trachea | 1994 |
Long-term infusion of kallikrein attenuates renal injury in Dahl salt-sensitive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Creatine; Cyclic GMP; Eicosanoids; Hemodynamics; Hypertension; Kallikreins; Kidney; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors | 1994 |
Analysis of responses to bradykinin and influence of HOE 140 in the isolated perfused rat lung.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Blood Pressure; Bradykinin; Captopril; In Vitro Techniques; Lung; Male; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Oxygen; Perfusion; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Respiration; Thromboxane A2 | 1994 |
Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Bradykinin; Captopril; Cardiomegaly; Dioxoles; Disease Models, Animal; Heart Failure; Hormones; Male; Molecular Sequence Data; Myocardial Infarction; Myocardium; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin | 1994 |
Analysis of responses to bradykinin: effects of Hoe-140 in the hindquarters vascular bed of the cat.
Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Bradykinin; Captopril; Cats; Cyclooxygenase Inhibitors; Enalaprilat; Female; Glyburide; Hindlimb; Male | 1994 |
Comparison of renal hemodynamic effect of ramiprilat to captopril; possible role of kinins.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Imidazoles; Kidney; Kinins; Losartan; Male; Rabbits; Ramipril; Renal Circulation; Tetrazoles | 1994 |
Cytosolic Ca2+ transients in endothelium-dependent relaxation of pig coronary artery, and effects of captopril.
Topics: Animals; Bradykinin; Calcium; Captopril; Coronary Vessels; Cytosol; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Fura-2; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Spectrometry, Fluorescence; Swine | 1993 |
Analysis of bradykinin-induced relaxations in the rat isolated anococcygeus muscle.
Topics: Animals; Arginine; Bradykinin; Captopril; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Nitroarginine; Rats; Receptors, Bradykinin; Superoxide Dismutase; Superoxides | 1994 |
Endothelium dependent vasomotor responses to endogenous agonists are potentiated following ACE inhibition by a bradykinin dependent mechanism.
Topics: Acetylcholine; Adenosine; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Bradykinin; Captopril; Coronary Circulation; Dogs; Drug Synergism; Enalapril; Endothelium, Vascular; Female; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Regional Blood Flow; Vasodilation | 1994 |
Prolongation by captopril of action potential duration in the normal and hypertrophied rat ventricle: direct action or inhibition of the local angiotensin converting enzyme?
Topics: Action Potentials; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cardiomegaly; Dose-Response Relationship, Drug; Heart; Hypertension; Indoles; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1994 |
Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs.
Topics: Alanine; Anesthesia; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cyclic GMP; Dogs; Drug Synergism; Female; Kidney; Male; Natriuresis; Neprilysin; Renal Circulation; Vascular Resistance; Vasodilation | 1994 |
Evidence for participation of B1 and B2 kinin receptors in formalin-induced nociceptive response in the mouse.
Topics: Animals; Binding, Competitive; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Edema; Formaldehyde; Male; Mice; Morphine; Nociceptors; Pain Measurement; Receptors, Bradykinin | 1993 |
Effect of captopril on vasoconstriction and Ca2+ fluxes in aortic smooth muscle.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Thoracic; Bradykinin; Calcium; Calcium Channels; Captopril; Cells, Cultured; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enalaprilat; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vasoconstriction | 1993 |
Chronic converting enzyme inhibition facilitates baroreceptor resetting to hypertensive levels.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Enalapril; Hypertension; Imidazoles; Losartan; Male; Pressoreceptors; Rats; Rats, Wistar; Reference Values; Regression Analysis; Tetrazoles | 1994 |
Coronary vasodilation to acetylcholine, adenosine and bradykinin in dogs: effects of inhibition of NO-synthesis and captopril.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Bradykinin; Captopril; Coronary Vessels; Dogs; Drug Synergism; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Vasodilation | 1993 |
Peptidases modulate bradykinin-induced arteriolar dilation in the hamster cheek pouch.
Topics: Animals; Arterioles; Bradykinin; Captopril; Cheek; Cricetinae; Drug Combinations; Endopeptidases; Glycopeptides; Isoproterenol; Male; Mesocricetus; Protease Inhibitors; Vasodilation | 1994 |
Bradykinin suppresses alcohol intake and plays a role in the suppression produced by an ACE inhibitor.
Topics: Alcohol Deterrents; Alcohol Drinking; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bradykinin; Captopril; Drinking; Male; Rats; Rats, Wistar | 1993 |
[Effect of bradykinin on airway epithelial ion transport and its modulation by endogenous peptidases].
Topics: Animals; Bradykinin; Captopril; Dogs; Dose-Response Relationship, Drug; Endopeptidases; Epithelium; Glycopeptides; In Vitro Techniques; Ion Transport; Lysine Carboxypeptidase; Mercaptoethanol; Trachea | 1993 |
Do angiotensin converting enzyme inhibitors limit myocardial infarct size?
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Heart Rate; Injections, Intravenous; Male; Myocardial Infarction; Rabbits; Ramipril; Renin | 1993 |
Role of bradykinin in microbial infection: enhancement of septicemia by microbial proteases and kinin.
Topics: alpha-Macroglobulins; Animals; Biotransformation; Bradykinin; Captopril; Endopeptidases; Leukocyte Elastase; Macroglobulins; Mice; Pancreatic Elastase; Protease Inhibitors; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Vibrio Infections | 1993 |
Captopril inhibits endothelin-1 secretion from endothelial cells through bradykinin.
Topics: Arginine; Bradykinin; Captopril; Cells, Cultured; Endothelins; Endothelium, Vascular; Humans; Nitric Oxide; Nitroarginine; Receptors, Bradykinin; Receptors, Neurotransmitter | 1993 |
Role of peptidases and NK1 receptors in vascular extravasation induced by bradykinin in rat nasal mucosa.
Topics: Animals; Biphenyl Compounds; Bradykinin; Capillary Permeability; Captopril; Evans Blue; Glycopeptides; Histocytochemistry; Nasal Mucosa; Neprilysin; Peptide Hydrolases; Rats; Rats, Inbred F344; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Urinary Bladder | 1993 |
Activation by Phoneutria nigriventer (armed spider) venom of tissue kallikrein-kininogen-kinin system in rabbit skin in vivo.
Topics: Alprostadil; Animals; Bradykinin; Capillary Permeability; Captopril; Edema; Histamine; Kallikrein-Kinin System; Kallikreins; Kininogens; Male; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter; Regional Blood Flow; Skin; Spider Venoms | 1993 |
Enhancement by captopril of bradykinin-induced calcium transients in cultured endothelial cells of the bovine aorta.
Topics: Animals; Aorta, Thoracic; Bradykinin; Calcium; Captopril; Cattle; Cells, Cultured; Coronary Vessels; Cytosol; Drug Synergism; Endothelium, Vascular; Fura-2; Muscle Relaxation; Muscle, Smooth, Vascular; Swine | 1993 |
Detection of the degradation products of bradykinin by enzyme immunoassays as markers for the release of kinin in vivo.
Topics: Amino Acid Sequence; Animals; Biomarkers; Bradykinin; Captopril; Carrageenan; Immunoenzyme Techniques; Male; Molecular Sequence Data; Peptide Fragments; Pleural Effusion; Pleurisy; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Time Factors; Trypsin Inhibitor, Bowman-Birk Soybean | 1993 |
Differential effects of captopril on regional haemodynamic responses to angiotensin I and bradykinin in conscious rats.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Heart Rate; Hemodynamics; Male; Mecamylamine; Rats; Regional Blood Flow; Vascular Resistance; Vasoconstriction | 1993 |
Role of locally formed angiotensin II and bradykinin in the reduction of myocardial infarct size in dogs.
Topics: Angiotensin II; Animals; Benzamidines; Bradykinin; Captopril; Dogs; Guanidines; Hemodynamics; Male; Myocardial Infarction; Oligopeptides; Serine Proteinase Inhibitors | 1993 |
Kinin actions on renal papillary blood flow and sodium excretion.
Topics: Animals; Arginine; Bradykinin; Captopril; Diuresis; Kidney Medulla; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride | 1993 |
Glucose transport activity in insulin-resistant rat muscle. Effects of angiotensin-converting enzyme inhibitors and bradykinin antagonism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Glucose; Indoles; Insulin; Insulin Resistance; Rats; Rats, Mutant Strains | 1996 |
Kininase II-type enzymes. Their putative role in muscle energy metabolism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Captopril; Dogs; Energy Metabolism; Guinea Pigs; Humans; Muscles; Myocardium; Neprilysin; Peptidyl-Dipeptidase A; Rats | 1996 |
B2 bradykinin receptors in cultured neonatal rat cardiomyocytes mediate a negative chronotropic and negative inotropic response.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bacitracin; Bradykinin; Captopril; Cells, Cultured; Heart; Heart Rate; Myocardial Contraction; Myocardium; Rats; Receptors, Bradykinin | 1996 |
Augmentation of coronary blood flow by ACE inhibition: role of angiotensin and bradykinin.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Coronary Vessels; Imidazoles; Losartan; Perfusion; Swine; Tetrazoles | 1995 |
Bradykinin B2 receptor-mediated chronotropic effect of bradykinin in isolated guinea pig atria.
Topics: Adrenergic beta-Agonists; Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Function; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Kallidin; Male; Myocardium; Nitric Oxide; Prostaglandins; Receptor, Bradykinin B2; Receptors, Bradykinin; Sensitivity and Specificity | 1995 |
Kinin-mediated antihypertensive effect of captopril in deoxycorticosterone acetate-salt hypertension.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Desoxycorticosterone; Hypertension; Kinins; Male; Nephrectomy; Rats; Rats, Wistar; Reference Values; Renal Circulation; Sodium Chloride; Time Factors | 1996 |
Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Biological Transport; Bradykinin; Captopril; Colon; Cyclic GMP; Dihydrolipoamide Dehydrogenase; Dinoprostone; In Vitro Techniques; Intestinal Mucosa; Ions; Models, Biological; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Vasodilator Agents | 1996 |
Bradykinin-evoked sensitization of airway sensory nerves: a mechanism for ACE-inhibitor cough.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cough; Guinea Pigs; Male; Receptor, Bradykinin B2; Trachea | 1996 |
The role of the endocardium in the facilitatory effect of bradykinin on electrically-induced release of noradrenaline in rat cardiac ventricle.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Electric Stimulation; Endocardium; Heart Ventricles; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Wistar; Tetrahydroisoquinolines; Ventricular Function | 1996 |
Comparative studies on differential inhibition of the renin - angiotensin system in the anesthetized guinea pig.
Topics: Alanine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Guinea Pigs; Imidazoles; Losartan; Male; Nephrectomy; Pyridines; Renin; Renin-Angiotensin System; Tetrazoles; Thiazoles | 1995 |
Bradykinin may not be involved in improvement of insulin resistance by angiotensin converting enzyme inhibitor.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Child; Diet; Fructose; Glucose; Glucose Intolerance; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Male; Rats; Rats, Wistar; Tetrazoles | 1996 |
Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cyclooxygenase Inhibitors; Hemodynamics; Imidazoles; Indomethacin; Kidney; Kidney Function Tests; Losartan; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Tetrazoles | 1996 |
Lack of contribution of circulatory kinin elevated by captopril to induce hypotension in normotensive and hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Desoxycorticosterone; Hypertension; Hypotension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley | 1996 |
The release of kininase from rat isolated hearts during myocardial ischaemia.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Bradykinin; Captopril; Edetic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Lysine Carboxypeptidase; Male; Myocardial Ischemia; Myocardium; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors | 1996 |
Pathophysiological and possible physiological roles of kinins in the pancreas.
Topics: Amylases; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Ceruletide; Cholecystokinin; Female; Infusions, Intravenous; Kinins; Pancreas; Rats; Rats, Sprague-Dawley | 1996 |
Kinin-induced prolongation of action-potential duration in right ventricular muscle from rat: involvement of B1 and B2 receptors.
Topics: 3-Mercaptopropionic Acid; Action Potentials; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Electrophysiology; Heart Ventricles; In Vitro Techniques; Kinins; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Ventricular Function, Right | 1996 |
Role of bradykinin receptors in the renal effects of inhibition of angiotensin converting enzyme and endopeptidases 24.11 and 24.15 in conscious rabbits.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Consciousness; Dipeptides; Enzyme Inhibitors; Heart Rate; Kidney; Metalloendopeptidases; Neprilysin; Oligopeptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits; Receptors, Bradykinin | 1996 |
Effects of captopril and Icatibant on bradykinin (BK) and des [Arg9] BK in carrageenan-induced edema.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Carrageenan; Disease Models, Animal; Edema; Foot Diseases; Hindlimb; Inflammation; Male; Rats; Rats, Wistar; Receptors, Bradykinin; Time Factors | 1996 |
Role of tachykinins in enhancement of bradykinin-induced bronchoconstriction by captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Bradykinin; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Male; Neurokinin A; Peptides, Cyclic; Piperidines; Substance P | 1996 |
Age-related decline in thirst and sodium appetite in rats related to kininase II inhibition.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Drinking; Female; Rats; Rats, Inbred F344; Sodium Chloride, Dietary | 1996 |
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.
Topics: Albumins; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Capsaicin; Captopril; Collagenases; Dose-Response Relationship, Drug; Edema; Glycopeptides; Hindlimb; Indoles; Inflammation; Isoindoles; Male; Matrix Metalloproteinase Inhibitors; Methysergide; Neurokinin-1 Receptor Antagonists; Oligopeptides; Organ Size; Protease Inhibitors; Rats; Rats, Wistar; Serotonin Antagonists; Substance P | 1996 |
Effects of ACE inhibition on spontaneous and insulin-stimulated endothelin-1 secretion: in vitro and in vivo studies.
Topics: Adult; Amnion; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Bradykinin; Captopril; Cell Membrane Permeability; Cells, Cultured; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Endothelin-1; Endothelium, Vascular; Glucose Tolerance Test; Humans; Hypertension; Insulin; Male; Nitric Oxide; Reference Values; Umbilical Veins | 1997 |
ACE inhibitors promote nitric oxide accumulation to modulate myocardial oxygen consumption.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Coronary Vessels; Culture Techniques; Dogs; Enalaprilat; Kallikrein-Kinin System; Kininogens; Male; Microcirculation; Myocardium; Nitric Oxide; Nitrites; Oxygen Consumption; Ramipril | 1997 |
In vivo inhibition of nitric oxide synthesis does not depend on renin-angiotensin system activation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cerebellum; Dogs; Enalapril; Enzyme Inhibitors; Female; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Renin-Angiotensin System | 1996 |
PGE2 production after angiotensin-converting enzyme inhibition.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Captopril; Dinoprostone; Enalapril; Female; Humans; Immune Tolerance; In Vitro Techniques; Indomethacin; Lymphocyte Activation; Male; Muromonab-CD3; T-Lymphocytes | 1997 |
[Effects pf captopril and D-penicillamine on kinins-mediated and chronic inflammation].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arthritis, Experimental; Bradykinin; Capillaries; Captopril; Dexamethasone; Edema; Immunosuppressive Agents; Kinins; Penicillamine; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1996 |
Spontaneously released substance P and bradykinin from isolated guinea-pig bladder.
Topics: Animals; Bradykinin; Captopril; Female; Glycopeptides; Guinea Pigs; Muscle Contraction; Peptidyl-Dipeptidase A; Protease Inhibitors; Substance P; Urinary Bladder | 1997 |
Activation of the contact system by filtration of platelet concentrates with a negatively charged white cell-removal filter and measurement of venous blood bradykinin level in patients who received filtered platelets.
Topics: Aged; alpha-Macroglobulins; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Platelets; Bradykinin; Captopril; Complement C1 Inactivator Proteins; Cricetinae; Female; Filtration; Humans; Hypotension; Kininogens; Leukapheresis; Male; Middle Aged; Peptidyl-Dipeptidase A; Platelet Transfusion; Prekallikrein; Transfusion Reaction | 1997 |
Angiotensin-converting enzyme inhibitors potentiate preconditioning through bradykinin B2 receptor activation in human heart.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Female; Heart; Heart Atria; Humans; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lisinopril; Male; Middle Aged; Receptors, Bradykinin | 1997 |
Effects of captopril on responses to bradykinin in the hindquarters vascular bed of the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Drug Evaluation, Preclinical; Drug Interactions; Endothelium, Vascular; Hindlimb; Injections, Intra-Arterial; Lung; Male; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1997 |
Role of angiotensin in the dipsogenic effect of bradykinin in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Bradykinin; Brain; Captopril; Cerebral Ventricles; Drinking; Imidazoles; Immunohistochemistry; Losartan; Male; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Thirst | 1997 |
Enhanced responsiveness of cardiac vagal chemosensitive endings to bradykinin in heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Captopril; Cardiac Output, Low; Dogs; Female; Heart Conduction System; Hemodynamics; Indomethacin; Male; Nerve Endings; Vagus Nerve | 1997 |
Interaction of kinins and captopril in regulating arterial smooth muscle cell proliferation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cell Division; Dose-Response Relationship, Drug; Female; Kinins; Mitosis; Muscle, Smooth, Vascular; Osmolar Concentration; Platelet-Derived Growth Factor; Rats; Rats, Wistar | 1997 |
Angiotensin-converting enzyme and neutral endopeptidase modulate smokeless tobacco-induced increase in macromolecular efflux from the oral mucosa in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Captopril; Cricetinae; Dextrans; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Glycopeptides; Lisinopril; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Neprilysin; Peptidyl-Dipeptidase A; Plants, Toxic; Protease Inhibitors; Thiorphan; Tobacco, Smokeless | 1997 |
Effect of captopril, losartan, and bradykinin on early steps of insulin action.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Insulin; Insulin Receptor Substrate Proteins; Liver; Losartan; Male; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin | 1997 |
Comparative effects of the angiotensin II receptor blocker EXP 3174 and of the angiotensin-converting enzyme inhibitor captopril on renal glomerular hemodynamics in the dog.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Dogs; Drug Combinations; Female; Glomerular Filtration Rate; Imidazoles; Kidney Glomerulus; Losartan; Male; Potassium; Sodium; Tetrazoles; Urea; Vascular Resistance; Vasodilation; Water | 1997 |
Blood pressure responses to acute or chronic captopril in mice with disruption of bradykinin B2-receptor gene.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Dose-Response Relationship, Drug; Drug Administration Routes; Gene Deletion; Hypertension; Male; Mice; Mice, Knockout; Receptor, Bradykinin B2; Receptors, Bradykinin; Vasoconstriction | 1997 |
Participation of kinins in the inhibitory action of captopril on acute hypertension induced by L-NAME in anesthetized rats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar | 1997 |
Possible involvement of placental proteases in bradykinin (BK) degradation.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood; Bradykinin; Captopril; Endopeptidases; Female; Glycopeptides; Humans; Hydrolysis; Lysine Carboxypeptidase; Microsomes; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Placenta; Pregnancy | 1997 |
Effects of sulphydryl- and non-sulphydryl-containing ACE inhibitors on left ventricular relaxation in the isolated guinea pig heart.
Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diastole; Female; Free Radical Scavengers; Guinea Pigs; Heart Ventricles; Hemoglobins; Isoquinolines; Lisinopril; Male; Muscle Relaxation; Nitric Oxide; Receptor, Bradykinin B2; Simethicone; Stroke Volume; Sulfhydryl Compounds; Superoxide Dismutase; Systole; Tetrahydroisoquinolines; Ventricular Dysfunction, Left | 1997 |
Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Coloring Agents; Data Interpretation, Statistical; Enalapril; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indicators and Reagents; Indoles; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Organometallic Compounds; Piperidines; Quinuclidines; Substance P; Time Factors | 1998 |
Mechanism of beta-adrenergic receptor upregulation induced by ACE inhibition in cultured neonatal rat cardiac myocytes: roles of bradykinin and protein kinase C.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Bradykinin; Captopril; Cells, Cultured; Female; In Vitro Techniques; Isoproterenol; Male; Myocardium; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Bradykinin; Tetrazoles; Up-Regulation | 1998 |
Ixodes scapularis: salivary kininase activity is a metallo dipeptidyl carboxypeptidase.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Assay; Bradykinin; Captopril; Carboxypeptidases; Chromatography, High Pressure Liquid; Cobalt; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Edetic Acid; Female; Guinea Pigs; Hydrogen-Ion Concentration; Ixodes; Manganese; Metalloendopeptidases; Peptide Fragments; Saliva; Salivary Glands; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1998 |
Bradykinin increases intracellular calcium levels in a human bronchial epithelial cell line via the B2 receptor subtype.
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Calcium; Captopril; Cell Line, Transformed; Cyclooxygenase Inhibitors; Epithelial Cells; Glycopeptides; Humans; Indomethacin; Protease Inhibitors; Receptor, Bradykinin B2; Receptors, Bradykinin; Simian virus 40 | 1998 |
Femtomolar bradykinin-induced relaxation of isolated bovine coronary arteries, mediated by endothelium-derived nitric oxide.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Vasodilation | 1998 |
Angiotensin II receptor antagonists for heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Captopril; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Receptors, Angiotensin | 1998 |
Angiotensin converting enzyme inhibition by captopril influences cardiac work in healthy hearts.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Circulation; Dose-Response Relationship, Drug; Heart; Male; Norepinephrine; Oxygen Consumption; Rats; Rats, Wistar | 1998 |
Purification and characterization of angiotensin I-converting enzymes from mesangial cells in culture.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cattle; Cells, Cultured; Chlorides; Chromatography, Gel; Enalaprilat; Glomerular Mesangium; Hydrogen-Ion Concentration; In Vitro Techniques; Isoenzymes; Molecular Weight; Oligopeptides; Peptidyl-Dipeptidase A; Rats; Substrate Specificity; Temperature | 1998 |
Inhibition of angiotensin-converting enzyme in human hand veins.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Dose-Response Relationship, Drug; Enalaprilat; Female; Hand; Humans; Male; Reference Values; Time Factors; Vasoconstriction; Vasodilation; Veins | 1999 |
Neurogenic plasma leakage in mouse airways.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Blood Vessels; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Captopril; Dose-Response Relationship, Drug; Evans Blue; Glycopeptides; Lung; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Piperidines; Protease Inhibitors; Quinuclidines; Receptors, Neurokinin-2; Skin; Specific Pathogen-Free Organisms; Substance P; Trachea; Urinary Bladder | 1999 |
Presence and comparison of angiotensin converting enzyme in commercial cell culture sera.
Topics: Angiotensin II; Animals; Blood Proteins; Bradykinin; Captopril; Cattle; Culture Media; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Horses; Humans; Inhibitory Concentration 50; Kinetics; Lisinopril; Oligopeptides; Peptidyl-Dipeptidase A; Silver Staining | 1999 |
Bradykinin and inhibition of angiotensin-converting enzyme in hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Drug Therapy, Combination; Humans; Hypertension; Losartan; Renin-Angiotensin System | 1999 |
Bradykinin and inhibition of angiotensin-converting enzyme in hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Drug Interactions; Humans; Kidney | 1999 |
Effects of captopril and bradykinin on chorda tympani-induced salivation in cat.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cats; Chorda Tympani Nerve; Cyclooxygenase Inhibitors; Electric Stimulation; Enzyme Inhibitors; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Salivation; Submandibular Gland | 1999 |
[Role of angiotensin-converting enzyme on bradykinin nasal provocation: comparison of normal volunteers and allergic subjects].
Topics: Adult; Albumins; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Female; Humans; Male; Nasal Mucosa; Nasal Provocation Tests; Peptidyl-Dipeptidase A; Proteins; Rhinitis, Allergic, Perennial | 1999 |
Kallidin- and bradykinin-degrading pathways in human heart: degradation of kallidin by aminopeptidase M-like activity and bradykinin by neutral endopeptidase.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Bradykinin; Captopril; CD13 Antigens; Dipeptides; Female; Glycopeptides; Heart Failure; Humans; Kallidin; Leucine; Male; Membrane Proteins; Middle Aged; Myocardium; Neprilysin; Peptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Substrate Specificity | 1999 |
Insulin sensitivity, clearance and release in kininogen-deficient rats.
Topics: Animals; Blood Glucose; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Glucose Clamp Technique; Glucose Tolerance Test; Insulin; Insulin Resistance; Insulin Secretion; Kininogens; Male; Rats; Rats, Wistar; Receptor, Bradykinin B2 | 1999 |
The bradykinin B1 receptor and the central regulation of blood pressure in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Brain; Captopril; Heart Rate; Hypertension; Injections, Intraventricular; Male; Oligonucleotides, Antisense; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Thionucleotides | 1999 |
Bradykinin B2 receptor antagonist icatibant reduces inhibitory effect of captopril on growth of cultured neonatal rat cardiomyocytes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cell Division; Cells, Cultured; Gene Expression; Genes, fos; Genes, myc; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Bradykinin down-regulates LPS-induced eosinophil accumulation in the pleural cavity of mice through type 2-kinin receptor activation: a role for prostaglandins.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bacterial Toxins; Bradykinin; Captopril; Down-Regulation; Enterotoxins; Eosinophils; Escherichia coli Proteins; Female; Injections, Spinal; Lipopolysaccharides; Male; Mice; Peritonitis; Pleura; Pleurisy; Prostaglandins; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin | 1999 |
ACE inhibition and glucose transport in insulinresistant muscle: roles of bradykinin and nitric oxide.
Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Female; Glucose; Imidazoles; Insulin Resistance; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker; Thiophenes | 1999 |
Role of bradykinin in postprandial hypotension in humans.
Topics: Adult; Aged; Antihypertensive Agents; Bradykinin; Captopril; Coloring Agents; Female; Humans; Hypotension; Indocyanine Green; Male; Middle Aged; Postprandial Period | 1999 |
A new experimental approach in endothelium-dependent pharmacological investigations on isolated porcine coronary arteries mounted for impedance planimetry.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcimycin; Captopril; Coronary Vessels; Diffusion; Dinoprost; Dose-Response Relationship, Drug; Electric Impedance; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Nitroprusside; Peptidyl-Dipeptidase A; Potassium; Pressure; Substance P; Swine; Time Factors; Vasoconstriction; Vasodilation | 1999 |
Nitric oxide modulates captopril-mediated angiotensin-converting enzyme inhibition in porcine iliac arteries.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Peptidyl-Dipeptidase A; S-Nitroso-N-Acetylpenicillamine; Swine; Vasoconstriction; Vasodilation | 1999 |
Bradykinin regulates captopril-induced upregulation of beta-adrenergic receptor in cultured neonatal rat cardiomyocytes.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Captopril; Cells, Cultured; Colforsin; Culture Media; Female; Isoproterenol; Male; Myocardium; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Adrenergic, beta; Receptors, Bradykinin; Up-Regulation | 2000 |
Maturation of the response to bradykinin in resistance and conduit pulmonary arteries.
Topics: Acetylcholine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Captopril; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Oxygen; Pulmonary Artery; Substance P; Swine; Vasoconstriction | 1999 |
Effect of kininase II inhibitors on bradykinin-stimulated bovine sperm motility.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cattle; Drug Synergism; Enalapril; Male; Sperm Motility | 1998 |
Inactivation of bradykinin by angiotensin-converting enzyme and by carboxypeptidase N in human plasma.
Topics: 3-Mercaptopropionic Acid; Adult; Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Blood Proteins; Bradykinin; Captopril; Enzyme Activation; Female; Humans; Lysine Carboxypeptidase; Male; Middle Aged; Peptidyl-Dipeptidase A; Protease Inhibitors; Tritium | 2000 |
Impaired endothelium-dependent regulation of ventricular relaxation in pressure-overload cardiac hypertrophy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Endothelium, Vascular; Guinea Pigs; Hypertrophy, Left Ventricular; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Substance P; Vasodilator Agents | 2000 |
Alpha-lactorphin lowers blood pressure measured by radiotelemetry in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Hypertension; Male; Naloxone; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid | 2000 |
Participation of kinins in the captopril-induced inhibition of intimal hyperplasia caused by interruption of carotid blood flow in the mouse.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Carotid Arteries; Hyperplasia; Kinins; Male; Mice; Muscle, Smooth, Vascular; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Regional Blood Flow | 2000 |
Effects of combined neutral endopeptidase 24-11 and angiotensin-converting enzyme inhibition on femoral vascular conductance in streptozotocin-induced diabetic rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Femoral Artery; Hemodynamics; Kininogens; Lysine Carboxypeptidase; Male; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Thiorphan; Time Factors | 2000 |
Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B(2) receptors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Calcium Signaling; Captopril; Cells, Cultured; Chagas Disease; CHO Cells; Cricetinae; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Humans; Kininogens; Kinins; Peptidyl-Dipeptidase A; Protozoan Proteins; Receptor, Bradykinin B2; Receptors, Bradykinin; Transfection; Trypanosoma cruzi; Umbilical Veins | 2000 |
Bradykinin (B2) independent effect of captopril on the development of pressure overload cardiac hypertrophy.
Topics: Animals; Aorta, Thoracic; Body Weight; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cardiomegaly; Heart; Heart Atria; Heart Rate; Heart Ventricles; Hydroxyproline; Male; Myosins; Organ Size; Rats; Rats, Wistar; Receptor, Bradykinin B2; Systole | 2000 |
Effects of converting enzyme inhibitors on renal P-450 metabolism of arachidonic acid.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arachidonic Acid; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Enalapril; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Kidney; Kidney Cortex; Kidney Medulla; Male; Microsomes; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spironolactone; Tetrazoles | 2001 |
Bradykinin mediates the acute effect of an angiotensin-converting enzyme inhibitor on cerebral autoregulation in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Vasodilation | 2001 |
Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C- and N-domain blockade.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Drug Synergism; Female; Humans; In Vitro Techniques; Isoquinolines; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Receptor, Bradykinin B2; Receptors, Bradykinin; Swine; Tetrahydroisoquinolines; Vasodilation | 2001 |
Absence of ligand-induced regulation of kinin receptor expression in the rabbit.
Topics: Anesthesia; Animals; Aorta; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cells, Cultured; Dextran Sulfate; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypotension; Interleukin-1; Kininogens; Ligands; Lipopolysaccharides; Male; Muscle, Smooth, Vascular; Rabbits; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Vasoconstriction | 2001 |
Proinflammatory characteristics of a nonpeptide bradykinin mimic, FR190997, in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Bronchoconstriction; Capillary Permeability; Captopril; Edema; Guinea Pigs; Inflammation; Lung; Male; Mice; Mice, Inbred ICR; Molecular Mimicry; Neovascularization, Pathologic; Quinolines; Rats; Receptor, Bradykinin B2; Receptors, Bradykinin; Reverse Transcriptase Polymerase Chain Reaction; Trachea | 2001 |
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission | 2001 |
Changes in blood glucose and plasma insulin levels induced by bradykinin in anaesthetized rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Epinephrine; Insulin; Male; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptors, Bradykinin | 2001 |
Bradykinin infusion in chronic cardiac failure and the effects of captopril.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Forearm; Heart Failure; Humans; Infusions, Intravenous; Male; Middle Aged; Renal Circulation; Treatment Outcome; Vasodilation | 2001 |
Bradykinin enhances sympathetic neurotransmission in rat blood vessels.
Topics: Adenosine Triphosphate; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Captopril; Cyclooxygenase Inhibitors; Drug Interactions; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Microelectrodes; Neuromuscular Junction; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles | 2002 |
Effect of valsartan and captopril in rabbit carotid injury. Possible involvement of bradykinin in the antiproliferative action of the renin-angiotensin blockade.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Carotid Artery Injuries; Cell Division; Endothelin-1; Female; Male; Rabbits; Renin-Angiotensin System; Tetrazoles; Thromboxane B2; Tunica Intima; Valine; Valsartan | 2001 |
Non-contribution of renin-angiotensin system to pressor response to N(G)-nitro-L-arginine in dogs.
Topics: Animals; Antihypertensive Agents; Arginine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bradycardia; Bradykinin; Captopril; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heart Rate; Injections, Intravenous; Male; Nitroarginine; Renin; Renin-Angiotensin System; Stereoisomerism; Tetrazoles | 2002 |
Studies on the angiotensin-converting enzyme and the kinin B2 receptor in the rabbit jugular vein: modulation of contractile response to bradykinin.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Enalaprilat; Jugular Veins; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rabbits; Receptor, Bradykinin B2; Receptors, Bradykinin; Vasoconstriction | 2002 |
Endothelial function in pigs transgenic for human complement regulating factor.
Topics: Angiotensin I; Animals; Antigens, CD; Bradykinin; Calcimycin; Captopril; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Humans; Male; Membrane Cofactor Protein; Membrane Glycoproteins; Natriuretic Peptide, C-Type; Nitric Oxide; Nitric Oxide Synthase; Swine; Vasodilation | 2002 |
Role of ACE and NEP in bradykinin-induced relaxation and contraction response of isolated porcine basilar artery.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Basilar Artery; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Receptor, Bradykinin B2; Swine; Thiorphan; Vasoconstriction; Vasodilation | 2002 |
The involvement of bradykinin in adrenaline-induced pulmonary edema in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Chi-Square Distribution; Enzyme Inhibitors; Epinephrine; Kallikreins; Lung; Male; NG-Nitroarginine Methyl Ester; Organ Size; Phentolamine; Pulmonary Edema; Random Allocation; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Bradykinin; Statistics as Topic; Vasoconstrictor Agents | 2001 |
Inhibition of angiotesin-converting enzyme by quercetin alters the vascular response to brandykinin and angiotensin I.
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Injections, Intravenous; Male; Quercetin; Rats; Rats, Wistar | 2002 |
Diuretic response to acute hypertension is blunted during angiotensin II clamp.
Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diuresis; Drug Synergism; Hypertension; Kidney; Lithium; Male; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2 | 2002 |
Modulation of cutaneous inflammation by angiotensin-converting enzyme.
Topics: Administration, Cutaneous; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; Captopril; Croton Oil; Dermatitis, Allergic Contact; Dermatitis, Irritant; Dinitrofluorobenzene; Disease Models, Animal; Female; Genetic Carrier Screening; Homozygote; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Receptor, Bradykinin B2 | 2003 |
Angiotensin-converting enzyme activity in ovine bronchial vasculature.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Bradykinin; Bronchi; Bronchial Arteries; Capillaries; Captopril; Dose-Response Relationship, Drug; Endothelial Cells; Hydrocortisone; In Vitro Techniques; L-Lactate Dehydrogenase; Microcirculation; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Pulmonary Artery; Regional Blood Flow; Sheep; Tumor Necrosis Factor-alpha | 2003 |
Interaction of noscapine with the bradykinin mediation of the cough response.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antitussive Agents; Bradykinin; Capsaicin; Captopril; Cough; Dose-Response Relationship, Drug; Drug Interactions; Enalapril; Guinea Pigs; Male; Naloxone; Narcotic Antagonists; Noscapine; Quinolines; Receptor, Bradykinin B2 | 2003 |
Captopril enhanced insulin-stimulated glycogen synthesis in skeletal muscle but not fatty acid synthesis in adipose tissue of hereditary hypertriglyceridemic rats.
Topics: Acylation; Adipose Tissue; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Esters; Fatty Acids; Fatty Acids, Nonesterified; Glucose; Glycerol; Glycogen; Hypertriglyceridemia; Hypoglycemic Agents; Insulin; Lactic Acid; Lipids; Male; Muscle, Skeletal; Postprandial Period; Rats; Rats, Wistar; Triglycerides | 2003 |
Characterization of new milk-derived inhibitors of angiotensin converting enzyme in vitro and in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Bradykinin; Captopril; Dipeptides; Inhibitory Concentration 50; Injections, Intravenous; Male; Milk; Milk Proteins; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Sprague-Dawley | 2003 |
The effect of acute angiotensin-converting enzyme and neutral endopeptidase 24.11 inhibition on plasma extravasation in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Lung; Male; Neprilysin; Peptidyl-Dipeptidase A; Plasma; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Substance P; Thiorphan | 2004 |
Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin-induced orofacial nociception in rats.
Topics: Animals; Arachidonic Acids; Atenolol; Behavior, Animal; Biogenic Amines; Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Captopril; Celecoxib; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Facial Pain; Formaldehyde; Guanethidine; Hindlimb; Indomethacin; Injections, Subcutaneous; Interleukin-6; Interleukin-8; Lip; Male; Meloxicam; Nociceptors; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Sulfonamides; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha; Tyramine | 2004 |
Angiotensin-(1-7) antagonist A-779 attenuates the potentiation of bradykinin by captopril in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Captopril; Drug Synergism; Hypertension; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Peptide Fragments; Rats; Rats, Wistar | 2004 |
Evidence for bradykinin as a stimulator of thirst.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aquaporin 2; Aquaporins; Blood Pressure; Bradykinin; Captopril; Creatinine; Drinking; Male; Polyuria; Rats; Rats, Sprague-Dawley; Thirst; Urine; Water | 2004 |
Purified angiotensin converting enzyme from Rana esculenta ovary influences ovarian steroidogenesis in vitro.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Female; Hydrogen-Ion Concentration; Lisinopril; Oligopeptides; Ovary; Rana esculenta; Renin; Sodium Chloride; Steroids; Temperature | 2003 |
Prostaglandin receptors EP2, EP3, and IP mediate exudate formation in carrageenin-induced mouse pleurisy.
Topics: Alprostadil; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Captopril; Carrageenan; Dinoprostone; Exudates and Transudates; Indomethacin; Kinetics; Mice; Mice, Knockout; Pleurisy; Prostaglandins; Quinolines; Receptors, Epoprostenol; Receptors, Prostaglandin E; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Captopril reverses the reduced vasodilator response to bradykinin in hypertensive pregnant rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Factors; Bradykinin; Captopril; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hypertension; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred SHR; Rats, Wistar; Splanchnic Circulation; Vasodilation; Vasodilator Agents | 2004 |
Selective angiotensin-converting enzyme C-domain inhibition is sufficient to prevent angiotensin I-induced vasoconstriction.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Dose-Response Relationship, Drug; Female; Femoral Artery; Humans; Male; Microcirculation; Middle Aged; Oligopeptides; Organ Specificity; Peptidyl-Dipeptidase A; Phosphinic Acids; Protein Structure, Tertiary; Solubility; Structure-Activity Relationship; Sus scrofa; Tetrahydroisoquinolines; Vasoconstriction | 2005 |
A bradykinin antagonist abolishes beneficial effect of captopril on duration of survival after acute coronary artery ligation in hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Captopril; Coronary Vessels; Heart Rate; Hypertension; Ligation; Male; Rats; Rats, Inbred SHR; Survival Rate | 2005 |
AT1 receptor in paraventricular nucleus mediates the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Blotting, Western; Bradykinin; Captopril; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Hemodynamics; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System | 2005 |
A possible alternative mechanism of kinin generation in vivo by cathepsin L.
Topics: Amino Acid Sequence; Animals; Antihypertensive Agents; Bradykinin; Captopril; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Hydrolysis; Kinins; Molecular Sequence Data; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Does insulin release kinins in rats?
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Female; Glucose; Hyperglycemia; Insulin; Isometric Contraction; Kinins; Rats; Rats, Wistar; Uterine Contraction | 2005 |
Kallidin-like peptide mediates the cardioprotective effect of the ACE inhibitor captopril against ischaemic reperfusion injury of rat heart.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Circulation; Creatine Kinase; Ischemic Preconditioning, Myocardial; Kallidin; Male; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2006 |
Effect of captopril in the presence of kinin B2 receptor antagonist on duration of survival after prolonged coronary artery ligation in hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Captopril; Coronary Vessels; Heart Rate; Hypertension; Ligation; Male; Rats; Rats, Inbred SHR; Survival Rate | 2006 |
Apoptosis and proliferation of mesangial cells isolated from kidneys undergoing compensatory growth following contralateral nephrectomy: role of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Bradykinin; Captopril; Cell Proliferation; Cell Separation; Cells, Cultured; Gene Expression Regulation; Mesangial Cells; Nephrectomy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger | 2007 |
Functional evidence of des-Arg10-kallidin enzymatic inactivating pathway in isolated human umbilical vein.
Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; CD13 Antigens; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Glycopeptides; Humans; In Vitro Techniques; Kallidin; Metalloproteases; Neprilysin; Peptides; Protease Inhibitors; Receptor, Bradykinin B1; Umbilical Veins; Vasoconstriction | 2007 |
ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin.
Topics: Angiotensin II; Animals; Apoptosis; Bradykinin; Bronchoalveolar Lavage Fluid; Captopril; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation Mediators; Losartan; Lung Diseases; Male; Peptidyl-Dipeptidase A; Pulmonary Gas Exchange; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiration, Artificial; Sensitivity and Specificity | 2008 |
B2 kinin receptor activation is the predominant mechanism by which trypsin mediates endothelium-dependent relaxation in bovine coronary arteries.
Topics: Animals; Bradykinin; Captopril; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Kallikreins; Receptor, Bradykinin B2; Receptor, PAR-1; Trypsin; Vasodilation | 2008 |
Isoflavone genistein inhibits the angiotensin-converting enzyme and alters the vascular responses to angiotensin I and bradykinin.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Fluorometry; Genistein; Male; Rats; Rats, Wistar | 2009 |
Cardioprotective effect of ornitho-kinin in an anesthetized, open-chest chicken model of acute coronary occlusion.
Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cardiotonic Agents; Chickens; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Kinins; Myocardial Infarction; Preoperative Care; Vascular Resistance; Vasodilator Agents | 2009 |
Neuroprotection against retinal ischemia-reperfusion injury by blocking the angiotensin II type 1 receptor.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Captopril; Cell Survival; Electroretinography; Enzyme-Linked Immunosorbent Assay; Female; Imidazoles; Immunoenzyme Techniques; Neuroprotective Agents; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Reperfusion Injury; Retina; Retinal Diseases; Retinal Ganglion Cells; Tetrazoles | 2010 |
Chronic treatment with quercetin does not inhibit angiotensin-converting enzyme in vivo or in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Chromatography, High Pressure Liquid; In Vitro Techniques; Injections, Intraperitoneal; Male; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar | 2010 |
Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity.
Topics: Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Captopril; Cell Count; Glycopeptides; Guinea Pigs; Histamine; Male; Ornithine; Ovalbumin; Parainfluenza Virus 3, Human; Peptides; Plethysmography, Whole Body; Pneumonia; Protease Inhibitors; Respirovirus Infections; Sulfonamides; Tissue Kallikreins | 2010 |
Differences between zofenopril and ramipril, two ACE inhibitors, on cough induced by citric acid in guinea pigs: role of bradykinin and PGE2.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Bronchoalveolar Lavage Fluid; Captopril; Citric Acid; Cough; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Male; Ornithine; Ramipril; Sulfonamides | 2010 |
Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits.
Topics: Anesthesia, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Citric Acid; Consciousness; Cough; Drug Evaluation, Preclinical; Injections, Intravenous; Male; Rabbits; Ramipril; Reflex | 2010 |
Casein-derived tripeptide Ile-Pro-Pro improves angiotensin-(1-7)- and bradykinin-induced rat mesenteric artery relaxation.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Hypertension; Male; Mesenteric Arteries; Oligopeptides; Peptide Fragments; Rats; Vasodilator Agents | 2011 |
Effect of captopril and the bradykinin-PKC pathway on ROS production in type 1 diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Bradykinin; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Insulin; Myocardium; Neutrophils; Oxidative Stress; Protein Kinase C; Rats, Inbred F344; Reactive Oxygen Species; Signal Transduction | 2011 |
Salt-dependent inhibition of epithelial Na+ channel-mediated sodium reabsorption in the aldosterone-sensitive distal nephron by bradykinin.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcium; Captopril; Epithelial Sodium Channels; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrons; Patch-Clamp Techniques; Peptidyl-Dipeptidase A; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Sodium; Sodium Chloride; Time Factors | 2012 |
ACE inhibition enhances bradykinin relaxations through nitric oxide and B1 receptor activation in bovine coronary arteries.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cattle; Coronary Vessels; Drug Synergism; Endothelium, Vascular; In Vitro Techniques; Muscle Relaxation; Nitric Oxide; Receptor, Bradykinin B1 | 2013 |
Angiotensin II type 2 receptor-mediated and nitric oxide-dependent renal vasodilator response to compound 21 unmasked by angiotensin-converting enzyme inhibition in spontaneously hypertensive rats in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fenoldopam; Imidazoles; Indomethacin; Kidney; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes; Vasodilation; Vasodilator Agents | 2013 |
Characterization of antidiabetic and antihypertensive properties of canary seed (Phalaris canariensis L.) peptides.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Captopril; Coronary Vessels; Digestion; Hypoglycemic Agents; Male; Myocardium; Nitric Oxide; Peptides; Peptidyl-Dipeptidase A; Phalaris; Rats; Rats, Wistar; Seed Storage Proteins; Seeds; Vasodilation; Vasodilator Agents | 2014 |
Comparative effects of a novel angiotensin-converting enzyme inhibitor versus captopril on plasma angiotensins after myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Disease Models, Animal; Male; Morpholines; Myocardial Infarction; Peptidyl-Dipeptidase A; Phenols; Rats; Rats, Wistar; Renin-Angiotensin System | 2014 |
Involvement of Renin-Angiotensin System in Damage of Angiotensin-Converting Enzyme Inhibitor Captopril on Bone of Normal Mice.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bone and Bones; Bradykinin; Captopril; Collagen Type I; Male; Mice, Inbred ICR; Peptidyl-Dipeptidase A; Phosphopeptides; Procollagen; Receptors, Bradykinin; Renin; Renin-Angiotensin System; Testosterone; Up-Regulation | 2015 |
Analysis of erectile responses to bradykinin in the anesthetized rat.
Topics: Anesthesia; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Captopril; Guanylate Cyclase; Male; Nitric Oxide Synthase; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilator Agents | 2015 |
Involvement of Kallikrein-Kinin System on Cardiopulmonary Alterations and Inflammatory Response Induced by Purified Aah I Toxin from Scorpion Venom.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Bradykinin; Bradykinin B2 Receptor Antagonists; Bronchoalveolar Lavage Fluid; Capillary Permeability; Captopril; Cytokines; Eosinophil Peroxidase; Kallikreins; Leukocyte Count; Male; Peroxidase; Pulmonary Edema; Rats; Rats, Wistar; Scorpion Venoms | 2016 |
Involvement of the TRPV1 receptor in plasma extravasation in airways of rats treated with an angiotensin-converting enzyme inhibitor.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Bronchi; Capillary Permeability; Capsaicin; Captopril; Male; Plasma; Rats; Rats, Wistar; Trachea; TRPV Cation Channels | 2016 |
Bradykinin -induced vasodilatation: Role of age, ACE1-inhibitory peptide, mas- and bradykinin receptors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Humans; Hypertension; Mesenteric Arteries; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, G-Protein-Coupled; Vasodilation | 2016 |
Panicolytic-like action of bradykinin in the dorsal periaqueductal gray through μ-opioid and B2-kinin receptors.
Topics: Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Anxiety Agents; Bradykinin; Bradykinin B2 Receptor Antagonists; Captopril; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Escape Reaction; Male; Panic; Periaqueductal Gray; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Opioid, mu; Somatostatin | 2017 |
Long-term feeding with bioactive tripeptides in aged hypertensive and normotensive rats: special focus on blood pressure and bradykinin-induced vascular reactivity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Bradykinin; Captopril; Cyclooxygenase 1; Hypertension; Kidney; Membrane Proteins; Mesenteric Arteries; Oligopeptides; Peptidyl-Dipeptidase A; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasodilator Agents | 2017 |
Captopril improves tumor nanomedicine delivery by increasing tumor blood perfusion and enlarging endothelial gaps in tumor blood vessels.
Topics: Animals; Antineoplastic Agents; Bradykinin; Brain Neoplasms; Capillary Permeability; Captopril; Cell Line, Tumor; Drug Delivery Systems; Endothelium, Vascular; Glioma; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Nanomedicine; Nanoparticles; Paclitaxel; Regional Blood Flow; Time Factors; Tumor Burden; Vasodilator Agents; Xenograft Model Antitumor Assays | 2017 |
Effect of rosmarinic acid on the arterial blood pressure in normotensive and hypertensive rats: Role of ACE.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Cinnamates; Depsides; Dose-Response Relationship, Drug; Hypertension; Lung; Male; Peptidyl-Dipeptidase A; Rats, Wistar; Rosmarinic Acid | 2018 |
Angiotensin-Converting Enzyme Inhibitor Rapidly Ameliorates Depressive-Type Behaviors via Bradykinin-Dependent Activation of Mammalian Target of Rapamycin Complex 1.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Humans; Hypertension; Mice; TOR Serine-Threonine Kinases | 2020 |