captopril has been researched along with angiotensin i in 431 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 207 (48.03) | 18.7374 |
| 1990's | 145 (33.64) | 18.2507 |
| 2000's | 49 (11.37) | 29.6817 |
| 2010's | 28 (6.50) | 24.3611 |
| 2020's | 2 (0.46) | 2.80 |
| Authors | Studies |
|---|---|
| Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 2 |
| Atkinson, AB; Brown, JJ; Davies, DL; Fraser, R; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI | 1 |
| Lefer, AM; Trachte, GJ | 1 |
| Johnston, CI; Matthews, PG; McGrath, BP | 2 |
| Dietz, R; Ganten, D; Mann, JF; Rascher, W; Schömig, A | 1 |
| Endo, J; Ikeda, F; Imura, H; Kono, T; Oseko, F | 2 |
| Johnston, CI; Matthews, PG | 1 |
| Atkinson, AB; Brown, JJ; Fraser, R; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI | 1 |
| Gotoh, M; Hata, T; Higaki, J; Kanda, T; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Ogihara, T | 1 |
| Dzau, VJ; Wilcox, CS | 1 |
| Leite, R; Salgado, MC | 1 |
| Alhenc-Gelas, F; Clauser, E; Corvol, P; Wei, L | 2 |
| Brée, F; Hamon, G; Tillement, JP | 1 |
| Li, T; Zimmerman, BG | 2 |
| Bost, JG; Leenders, PJ; Nelissen-Vrancken, MH; Smits, JF; Struijker-Boudier, HA | 1 |
| Albano, V; Albiero, R; Di Pasquale, P; Licata, G; Paterna, S; Trombino, G; Valdes, L; Valenza, M; Vitrano, G | 1 |
| Criscuoli, M; Giachetti, A; Guelfi, M; Sardelli, G; Subissi, A | 1 |
| Balfagón, G; Encabo, A; Ferrer, M; Marín, J | 1 |
| Davies, E; Edwards, CR; Flapan, AD; Rademaker, M; Shaw, TR; Williams, BC | 1 |
| Blair-West, JR; Denton, DA; McKinley, MJ; Weisinger, RS | 1 |
| de Jong, JW; Huizer, T; van der Meer, P | 1 |
| De Mey, JG; Schiffers, PM; Struyker-Boudier, HA | 1 |
| Imai, S; Ishibashi, T; Mitomi, A; Tanaka, M; Tatebe, S | 1 |
| Fortier, P; Godin, D; Lambert, C; Nadeau, R | 1 |
| Arakawa, K; Ideishi, M; Ikeda, M; Sasaguri, M | 3 |
| Bönner, G; Kaufmann, W; Preis, S; Schunk, U; Toussaint, C | 1 |
| Jackson, EK | 1 |
| Brunner, HR; Evéquoz, D; Flückiger, JP; Hui, KY; Nussberger, J; Waeber, B | 1 |
| Admiraal, PJ; Danser, AH; Derkx, FH; Sassen, LM; Schalekamp, MA; Verdouw, PD | 1 |
| Franco-Saenz, R; Lotshaw, DP; Mulrow, PJ; Oda, H | 1 |
| Story, DF; Ziogas, J | 1 |
| Beutler, JJ; Boer, P; Dorhout Mees, EJ; Koomans, HA; Rabelink, AJ; Vos, PF | 1 |
| Andersson, B; Eriksson, S | 1 |
| Ribeiro, C | 1 |
| Cooke, JP; Han, BJ; Lee, F; Loscalzo, J; Shaffer, JE; Thomson, S | 1 |
| Kerkhoff, J; van den Buuse, M | 1 |
| Ganten, D; Hilgenfeldt, U; Hilgers, KF; Mann, JF | 1 |
| Matsuo, H; Nishida, M; Obata, H; Sano, H; Yasuda, H | 1 |
| Bigorgne, JC; Corvol, P; Denolle, T; Galland, F; Guyene, TT; Rohmer, V; Saint-Adnré, JP; Schambelan, M | 1 |
| Andries, LJ; Brutsaert, DL; Meulemans, AL | 1 |
| Dzau, VJ; Stevenson, L; Tang, SS | 1 |
| Bumpus, FM; Healy, B; Husain, A; Stewart, RW; Urata, H | 1 |
| Bumpus, FM; Daud, AI; Husain, A | 1 |
| Ganten, D; Hellmann, T; Keuneke, C; Metzger, R; Peters, J; Yacullo, R | 1 |
| Rónai, AZ | 1 |
| Fu, WO; Huang, SJ; Law, WK; Wong, PY | 1 |
| Uchendu, CN; Wong, PY | 1 |
| Epstein, WL; Fukuyama, K; Hirayama, K | 1 |
| Bumpus, FM; Fouad-Tarazi, FM; Healy, B; Hirakata, H; Husain, A; Khosla, M; Kumagai, H; Urata, H | 1 |
| Braso, MA; Gubert, S; Ortiz, JA; Sacristán, A | 1 |
| Karmarkar, MG; Lall, SB; Menon, SM; Seth, SD; Siddiqui, HH | 1 |
| Campbell, DJ; Kladis, A; Ziogas, J | 1 |
| Hasegawa, Y; Takei, Y | 1 |
| Center, DM; Danilov, SM; Farber, HW; Rounds, S | 1 |
| Ganten, D; Jin, MW; Lindpaintner, K; Niedermaier, N; Wilhelm, MJ | 1 |
| Brunner, HR; Christen, Y; Nussberger, J; Waeber, B | 1 |
| Barer, GR; Cai, YN; Emery, CJ; Howard, P; Russell, PC | 1 |
| Rump, LC; Schollmeyer, P; Schuster, MJ; Wilde, K | 1 |
| Drummer, OH; Johnson, H; Kourtis, S | 1 |
| Dai, S; Hui, SC; Ogle, CW | 1 |
| Belz, GG; Essig, J; Wellstein, A | 3 |
| Giesen-Crouse, EM; Imbs, JL; Krieger, JP; Schmidt, M; Welsch, C | 1 |
| Li, T; Rassier, ME; Zimmerman, BG | 1 |
| Aalkjaer, C; Juul, B; Mulvany, MJ | 1 |
| Ambrosioni, E; Borghi, C; Boschi, S; Capelli, M; Costa, FV; Magelli, C; Magnani, B; Varani, E | 1 |
| Endoh, M; Kakemi, M; Katayama, K; Koizumi, T; Suzuki, M | 1 |
| Brinck-Johnsen, T; Colpoys, MC; Conrad, KP; Morganelli, PM | 1 |
| Ayers, CR; Baker, KM; Lehman, MR; Lewis, RA; Weaver, BA | 1 |
| Frederickson, ED; Phillips, MI; Smith, TB; Wilcox, CS; Williams, CM; Wingo, CD | 1 |
| Andon, N; Cooke, JP; Loscalzo, J | 1 |
| Haber, E; Hartley, LH; Hui, KY; Knight, DR; Nussberger, J; Vatner, SF | 1 |
| Ganten, D; Hilgers, KF; Kuczera, M; Mann, JF; Ritz, E; Wiecek, A; Wilhelm, MJ | 1 |
| Fukuchi, S; Hashimoto, S; Inagami, T; Mizuno, K; Niimura, S; Satoh, A; Shimamoto, K; Tani, M | 1 |
| Majewski, H; Mian, MA; Rand, MJ | 1 |
| Admiraal, PJ; Danser, AH; Derkx, FH; Schalekamp, MA | 1 |
| Bendhack, LM; Lindsey, CJ; Paiva, AC | 1 |
| Fryer, JN; Weld, MM | 1 |
| Chen, X; Li, K | 1 |
| Nakagawa, M; Nakamura, Y; Nakanishi, Y; Sasaki, S; Sawada, S; Takamatsu, H; Takeda, K; Toyoda, T; Tsuji, H; Uno, M | 1 |
| Chardigny, JM; Diebold, H; Moreau, D; Rochette, L | 1 |
| de Nucci, G; Vane, JR; Warner, T | 1 |
| Fregly, MJ; Rowland, NE | 2 |
| Li, CG; Majewski, H; Rand, MJ | 1 |
| Barabé, J; D'Orléans-Juste, P; Dion, S; Drapeau, G; Regoli, D; Rhaleb, NE; Rovero, P; Ward, P | 1 |
| Brosnihan, KB; Ferrario, CM; Saruta, T; Suzuki, H | 1 |
| Bührle, CP; Rosivall, L; Taugner, R | 1 |
| Giesen-Crouse, E; Imbs, JL; Krieger, JP; Schmidt, M; Welsch, C | 1 |
| Beswick, E; Bumpus, FM; Cross, RB; Dallemagne, C; Khosla, MC | 1 |
| Esser, H; Heck, I; Kikis, D; Stumpe, KO | 1 |
| Pham, DV; Tan-Wilson, HI; Wilson, JX | 1 |
| Di Perr, T | 1 |
| Cobden, I; Record, CO; Shore, A; Wilkinson, R | 1 |
| Cohen, ML; Mueller, SM | 1 |
| Johnson, AL; Price, WA; Stump, JM; Vavala, RF; Wong, PC | 1 |
| Canonico, PL; MacLeod, RM | 1 |
| Endoh, M; Kakemi, M; Katayama, K; Koizumi, T; Kuroda, T; Suzuki, M | 1 |
| Damkjaer Nielsen, M; Giese, J; Ibsen, H; Leth, A; Nielsen, F; Rasmussen, S | 1 |
| Bonde-Petersen, F; Christensen, NJ; Damkjaer Nielsen, M; Giese, J; Hesse, B; Rasmussen, S; Warberg, J | 1 |
| Fukuya, F; Hosoki, K; Kadokawa, T; Kawahara, S; Minato, H; Takeyama, K | 1 |
| Snyder, RA; Wintroub, BU | 1 |
| Ijichi, H; Maebo, N; Nakagawa, M; Niwa, I; Sawada, S; Takamatsu, H; Toyoda, T; Tsuji, H | 1 |
| Ehlers, MR; Kirsch, RE; Maeder, DL | 1 |
| Cadieux, A; Sirois, P | 1 |
| Nelson, EB; Pool, JL; Taylor, AA | 1 |
| Bouhnik, J; Corvol, P; Jaramillo, HN; Menard, J; Sambhi, MP | 1 |
| Imura, H; Khosla, MC; Kono, T; Oseko, F; Taniguchi, A | 2 |
| Fujisawa, M; Hidaka, H; Okabe, T; Takaku, F; Umezawa, Y; Yamagata, K | 1 |
| Britton, SL; Metting, PJ | 1 |
| Ijichi, H; Nakagawa, M; Sawada, S; Takamatsu, H; Toyoda, T; Tsuji, H | 1 |
| Miyazaki, M; Nishimura, K; Okunishi, H; Toda, N | 1 |
| Whalley, ET | 1 |
| Fitzsimons, JT; Fuller, LM | 1 |
| Barnett, A; Baum, T; Pula, K; Tedesco, RP; Watkins, RW | 1 |
| Drummer, OH; Kourtis, S | 1 |
| Bumpus, FM; Fouad-Tarazi, FM; Healy, B; Khosla, M | 1 |
| Rom, MB; Weller, HN | 1 |
| Anderson, PW; Do, YS; Hsueh, WA; Lee, FO; Quismorio, FP; Troum, OM | 1 |
| Kobayashi, H; Okawara, Y | 1 |
| Changaris, DG; Levy, RS; Miller, JJ; Porter, JL | 1 |
| Guidi, E; Hollenberg, NK | 1 |
| Inagami, T; Kumahara, Y; Nakamaru, M; Ogihara, T | 1 |
| Heiman, D; McKenzie, IM; McKenzie, JK; Winter, JS | 1 |
| Ito, M; Maeyama, M; Matsui, K; Nakamura, T; Yoshimura, T | 1 |
| Damkjaer Nielsen, M; Giese, J; Hesse, B; Høilund-Carlsen, PF; Rasmussen, S | 1 |
| Giot, JM; Staroukine, MA; Verniory, AE | 1 |
| Itaya, Y; Kondo, K; Matsukawa, S; Saruta, T; Suzuki, H | 1 |
| Koreen, R; Krakoff, LR; Yagil, Y | 1 |
| Dostal, DE; Johnson, JA | 1 |
| Chan, MY; Chiu, KW; Pang, PK; Wong, VC | 1 |
| Lee, TJ; Su, C; Urabe, M | 1 |
| Atkinson, J; Boillat, N; Essadki, A; Lüthi, P; Maranda, B; Sonnay, M | 1 |
| Hosokawa, T; Howard, RB; Maguire, MH | 1 |
| Atrash, B; Beattie, S; Donovan, B; Hallett, A; Hughes, M; Jones, DM; Leckie, BJ; Lever, AF; Szelke, M; Tree, M | 1 |
| Aniya, Y; Ito, H; Kato, T; Noguchi, K; Sakanashi, M | 1 |
| Inagami, T; Misono, KS; Nakamaru, M; Naruse, M; Workman, RJ | 1 |
| Heck, I; Knopp, R; Kropp, J; Ledda, R; Mattern, H; Reske, SN; Winkler, C | 1 |
| Dal Palù, C; De Toni, R; Feltrin, G; Mozzato, MG; Perissinotto, F; Pessina, AC; Rossi, G; Semplicini, A | 1 |
| Center, DM; Farber, HW; Rounds, S | 1 |
| Harper, RA; Stephens, GA | 1 |
| Bjøro, K | 1 |
| Britton, SL; Fiksen-Olsen, MJ; Houck, PC; Romero, JC | 2 |
| Gaul, SL; Martin, GE; Sweet, CS | 1 |
| Giese, J; Hesse, B; Høilund-Carlsen, PF; Nielsen, MD; Rasmussen, S | 1 |
| Atlas, SA; Case, DB; Laragh, JH; Yu, ZY | 1 |
| Alhenc-Gelas, F; Corvol, P; Menard, J; Yasui, T | 1 |
| Funae, Y; Komori, T; Takada, T; Yamamoto, K | 1 |
| Becker, RH; Metzger, M; Schölkens, BA; Schulze, KJ | 1 |
| Morton, JJ; Wallace, EC | 1 |
| Ahn, HS; Baum, T; Czarniecki, M; Eynon, E; Nelson, S; Sybertz, EJ; Washington, P | 1 |
| Ganten, D; Hermann, K; Lang, RE; McDonald, W; Unger, T | 1 |
| Giese, J; Ibsen, H; Nielsen, MD; Rasmussen, S | 1 |
| Bletry, O; Godeau, P; Guillevin, L; Herson, S; Leenhardt, A | 1 |
| Cline, WH; Kawasaki, H; Su, C | 1 |
| Fregly, MJ; Kikta, DC | 1 |
| Limone, P; Molinatti, GM | 1 |
| Hashimoto, K; Ohara, N; Ono, H | 1 |
| Jandhyala, B; Kjellstedt, A; Ljung, B | 1 |
| Arbegast, PT; Blaine, EH; Gaul, SL; Gross, DM; Sweet, CS | 1 |
| Iso, T; Iwao, J; Nakata, K; Nishimura, K; Suda, H; Yamauchi, H | 1 |
| Larsson-Backstrom, C | 1 |
| Hayashi, Y; Kan, T; Kawabe, T; Kokubu, T; Ono, M; Ueda, E | 1 |
| Casley, DJ; Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 1 |
| Abe, I; Fukiyama, K; Kawano, Y; Kawasaki, T; Kawazoe, N; Ogata, M; Omae, T; Ueno, M; Uezono, K | 1 |
| Shigetomi, S | 1 |
| Amery, AK; Fagard, RH; Lijnen, PJ; Reybrouck, TM | 1 |
| Antonaccio, MJ; Cheung, HS; Cushman, DW; Murthy, VS; Ondetti, MA; Rubin, B | 1 |
| Eguchi, T; Nakamura, R; Saito, I; Saruta, T; Yasui, T | 1 |
| Brunner, HR; Gavras, H; Turini, GA; Waeber, B; Wauters, JP | 1 |
| Casals-Stenzel, J; Morton, JJ; Tree, M | 2 |
| Atkinson, AB; Brown, JJ; Fraser, R; Lever, AF; Morton, JJ; Riegger, AJ; Robertson, JI | 1 |
| Hammat, MT; Johnston, CI; Millar, JA | 1 |
| Wong, PC; Zimmerman, BG | 2 |
| de Bruyn, JH; Derkx, FH; Man in 't Veld, AJ; Schalekamp, MA; Wenting, GJ | 1 |
| Garcia Del Rio, C; Morton, JJ; Smellie, WS | 1 |
| Carey, RM; Levens, NR; Peach, MJ; Vaughan, ED; Weed, WC | 1 |
| Fregly, MJ; Palmore, WP; Simpson, CF | 1 |
| Coghlan, JP; Denton, DA; Fei, DT; Mason, RT; Scoggins, BA; Stewart, KW; Whitworth, JA | 1 |
| Backlund, EP; Bohn, DL; Gross, DM; Morris, AA; Stone, CA; Sweet, CS; Ulm, EH; Vassil, TC; Weitz, D; Wenger, HC | 1 |
| Antonaccio, MJ; Cushman, DW | 1 |
| Cervoni, P; Herzlinger, H; Lai, FM; Tanikella, T; Thibault, L | 1 |
| Ikeda, T; Kawai, K; Koike, H; Komai, T; Miyamota, M; Shindo, H | 1 |
| Ganten, D; Hübner, D; Lang, RE; Rascher, W; Schüll, B; Unger, T; Yukimura, T | 2 |
| Iansek, R; Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 1 |
| Cushman, DW; Ondetti, MA | 1 |
| Kohlmann, O; Marson, O; Ramos, OL; Ribeiro, AB; Tufik, S | 1 |
| Cohen, ML; Kurz, KD | 1 |
| Satoh, S; Suzuki, M | 1 |
| Kumahara, Y; Mikami, H; Morikawa, T; Ogihara, T; Sakakibara, S | 1 |
| Biollaz, J; Brunner, HR; Burnier, M; Gavras, H; Turini, GA | 1 |
| Sheridan, MA; Ward, PE | 1 |
| Beuers, U; Hertting, G; Knepel, W | 1 |
| Melli, M; Türker, RK | 1 |
| Bouhnik, J; Clauser, E; Corvol, P; Genain, C; Ménard, J | 1 |
| Angus, JA; Johnston, CI; Nakashima, A | 2 |
| Elfont, RM; Fitzsimons, JT | 1 |
| Balment, RJ; Henderson, IW; McKeever, A; Oliver, JA | 1 |
| Sweet, CS | 1 |
| Baum, T; Becker, FT; Sybertz, EJ | 1 |
| Di Nicolantonio, R; Hutchinson, JS; Mendelsohn, FA | 1 |
| Lefer, AM; Lefer, DJ | 1 |
| Bouhnik, J; Clauser, E; Corvol, P; Gonzalez, MF; Menard, J | 1 |
| Damkjaer Nielsen, M; Giese, J; Ibsen, H; Leth, A; Rasmussen, S | 1 |
| Loev, B; Mann, WS; Smith, RD; Suh, JT; Wolf, PS | 1 |
| Cohen, DM; Essenburg, AD; Kaplan, HR; Major, TC; Mertz, TE; Ryan, MJ | 1 |
| Hess, ML; Manson, NH | 1 |
| Chen, X; Gillis, CN; Moalli, R; Pitt, BR | 1 |
| Gaida, W; Ganten, D; Kraft, K; Lang, RR; Unger, T | 1 |
| Dzau, VJ; Herrmann, HC | 1 |
| Carmines, PK; Tanner, GA | 1 |
| Koepke, JP; Obrist, PA | 1 |
| Düsing, R; Glänzer, K; Kramer, HJ; Landsberg, G; Scherhag, R | 1 |
| Balment, RJ; Carrick, S | 1 |
| Chesney, RW; Friedman, AL | 1 |
| Corvol, P; Gonzales, MF; Ménard, J; Misumi, J; Ogihara, T | 1 |
| Denef, C; Schramme, C | 1 |
| Cipolle, MD; Zehr, JE | 1 |
| Harding, JW; LaCrosse, E; Morseth, SL; Wright, JW | 1 |
| Manwaring, D; Mullane, K | 1 |
| Chiu, KW; Ho, BY; Sham, JS | 1 |
| Chaud, M; Gimeno, AL; Gimeno, MF; Viggiano, M | 1 |
| Coghlan, JP; Fei, DT; Scoggins, BA; Tresham, JJ | 1 |
| Atkinson, AB; Brown, JJ; Cumming, AM; Fraser, R; Leckie, BJ; Lever, AF; Morton, JJ; Robertson, JI | 1 |
| Bertinieri, G; Buccino, N; Ferrari, A; Grassi, G; Gregorini, L; Mancia, G; Parati, G; Pomidossi, G; Rupoli, L; Zanchetti, A | 1 |
| Hayduk, K; Liebau, G; Riegger, GA; Steilner, H | 1 |
| Reilly, CF; Schechter, NM; Tewksbury, DA; Travis, J | 1 |
| Appelgren, B; Eriksson, S; Jónasson, H; Rundgren, M | 1 |
| Amery, A; Fagard, R; Lijnen, P; Verschueren, L | 1 |
| Miller, SH; Petty, MA; Reid, JL | 1 |
| Grodzińska, L; Gryglewski, RJ | 1 |
| DeWolf, R; Goodman, S; Gould, AB; Onesti, G; Swartz, C | 1 |
| Goto, A | 1 |
| Moncada, S; Mullane, KM | 1 |
| Ball, D; Chesney, RW; Friedman, A; Goodfriend, T | 1 |
| Antonaccio, MJ; Horovitz, ZP; Rubin, B | 1 |
| Morton, JJ; Tree, M | 1 |
| Fregly, MJ; Lockley, OE; Simpson, CE | 1 |
| Clarke, DE; Wagner, LA; Wagner, LB | 1 |
| Collis, MG; Keddie, JR | 1 |
| Braley, LM; Menachery, A; Williams, GH | 1 |
| Dusting, GJ; Mullins, EM; Nolan, RD | 1 |
| Friedman, P; Kounenis, G; Kraft, E; Wong, PC; Zimmerman, BG | 1 |
| Angeli, A; Angelino, PF; Gastaldo, D; Lavezzaro, GC; Minelli, M; Paccotti, P | 1 |
| Amery, A; Fagard, R; Lijnen, P; Roussel-Deruyck, R | 1 |
| Atkinson, AB; Brown, JJ; Cumming, AM; Fraser, R; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI | 1 |
| Blair, ML; Ramsay, DJ; Sladek, CD | 1 |
| Bazil, MK; Krulan, C; Webb, RL | 1 |
| Laurent, V; Salzet, M | 1 |
| Clark, KL; Drew, GM; Robertson, MJ | 1 |
| Drapeau, G; Marceau, F; Rioux, F | 1 |
| Gibson, KJ; Lumbers, ER; Stevenson, KM | 1 |
| Garrison, EA; Kadowitz, PJ; Osei, SY; Santiago, JA | 1 |
| Butler, DG; Cadinouche, MZ; Oudit, GY | 1 |
| Chowdury, S; Danser, AH; de Lannoy, LM; Saxena, PR; Schalekamp, MA; van der Giessen, WJ | 1 |
| de Moura, R; Lopes, MA | 1 |
| Sim, MK; Yuan, HT | 1 |
| Karmarkar, MG; Lall, SB; Peshin, SS | 1 |
| Gabel, M; Hoit, BD; Husain, A; Kinoshita, A; Shao, Y; Walsh, RA | 1 |
| Cimmerer, AL; Fregly, MJ; Rowland, NE | 1 |
| Botyánszki, J; Fehér, E; Hepp, J; Magyar, A; Medzihradszky, K; Rónai, AZ | 1 |
| Arakawa, K; Ideishi, M; Kinoshita, A; Miura, S; Motoyama, M; Sakai, T; Sasaguri, M; Shindo, M; Tanaka, H | 1 |
| Belz, GG; Breithaupt, K; Erb, K | 1 |
| Johnson, AK; Morris, M; Thunhorst, RL | 1 |
| Cheng, DY; DeWitt, BJ; Kadowitz, PJ; McMahon, TJ | 1 |
| Andersson, KE; Hedlund, H; Lindberg, BF; Nilsson, LG; Stahl, M | 1 |
| Bralet, J; Gros, C; Lecomte, JM; Marie, C; Mossiat, C; Schwartz, JC | 1 |
| Azizi, M; Chatellier, G; Guyene, TT; Ménard, J | 1 |
| Radhakrishnan, R; Sim, MK | 1 |
| Coleman, CC; Simon, G | 1 |
| Albano, V; Albiero, R; Cannizzaro, S; Di Pasquale, P; Licata, G; Paterna, S; Trombino, G; Valdes, L; Valenza, M; Vitrano, G | 1 |
| Cardinal, R; de Champlain, J; Godin, D; Gouin, L; Moreau, P; Nadeau, R; Ribuot, C; Rochette, L; Vermeulen, M | 1 |
| Asaad, M; Rogers, WL; Seymour, AA; Sheldon, JH; Smith, PL | 1 |
| Feng, CJ; Kadowitz, PJ; Nossaman, BD; Wang, J | 1 |
| Buchholz, RA; Cushing, DJ; Ellery, SS; Hoover, KW; Johnson, HA; Knight, DR; MacAndrew, JT; Magee, WP; Mangiapane, ML; Rauch, AL | 1 |
| Fischli, W; Hilgers, KF; Mann, JF; Veelken, R | 1 |
| Mizutani, S; Tomoda, Y | 1 |
| Chen, W; Cheng, D; Ji, C; Tang, S; Wang, B | 1 |
| da Silva, SV; da Silva, VJ; Salgado, HC; Salgado, MC | 1 |
| Berecek, KH; Wu, JN | 1 |
| Kawamoto, T; Miyazaki, M; Oka, Y; Okunishi, H; Shiota, N; Song, K | 1 |
| Brooks, DP; DePalma, PD; Fredrickson, TA; Ruffolo, RR; Spielman, WS | 1 |
| Bumpus, FM; Husain, A; Kinoshita, A; Urata, H | 1 |
| Klaus, W; Korth, A; Rösen, R; Rump, AF | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA | 1 |
| Ganten, D; Hilgenfeldt, U; Hilgers, KF; Luft, FC; Mann, JF; Muley, T; Veelken, R | 1 |
| Fukamizu, A; Hatae, T; Kajiwara, N; Murakami, K; Seo, MS; Sugimura, K; Sugiyama, F; Takahashi, S; Takimoto, E; Yagami, K | 1 |
| Aneshansley, DJ; Gorewit, RC; Jiang, J | 1 |
| Allen, GT; Powell, JR; Tesfamariam, B | 1 |
| Ishii, K; Nakahara, T; Nakayama, K; Tanaka, Y | 1 |
| Balcells, E; Dell'Italia, LJ; Durand, JN; Hageman, GR; Meng, QC; Palmer, RW | 1 |
| Brosnihan, KB; Fernandez, C; Ferrario, CM; Luque, M; Martell, N; Martin, P | 1 |
| Haneda, T; Kikuchi, K; Miyata, S; Osaki, J | 1 |
| Auguet, M; Chabrier, PE; Delaflotte, S; Zerrouk, A | 1 |
| Berglund, L; Reneland, R | 1 |
| Djahanbakhch, O; Evans, S; Holt, WV; Matthews, S; Mehta, J; Puddefoot, JR; Saridogan, E; Vinson, GP | 1 |
| Decker-Hermann, PJ; Haberl, RL; Hermann, K | 1 |
| Garrison, EA; Kadowitz, PJ | 1 |
| Bohlender, J; Costerousse, O; Dragun, D; Hilgers, KF; Luft, FC; Ménard, J; Müller, DN | 1 |
| Colvill, LM; Giles, ME; McKinley, MJ; Oldfield, BJ | 1 |
| Moore, JN; Tillman, LG | 1 |
| Kawai, Y; Matsuki, M; Nishida, S; Sumitomo, S; Yoneda, M | 1 |
| Chauvet, MT; Corvol, P; Michaud, A; Williams, TA | 1 |
| Balcells, E; Dell'Italia, LJ; Durand, J; Hageman, GR; Hankes, GH; Meng, QC; Oparil, S; Palmer, R; Wei, CC | 1 |
| de Lannoy, LM; Jan Danser, AH; Schalekamp, MA; van Kats, JP; van Meegen, JR; Verdouw, PD | 1 |
| Burke, SE; Dayton, BD; Gagne, GD; Lubbers, NL; Opgenorth, TJ; Wegner, CD; Wessale, JL | 1 |
| Böhm, M; Ettelbrück, S; Flesch, M; Knorr, A; Pinto, Y; Schiffer, F; Stasch, JP; Zolk, O | 1 |
| Anderson, DR; Chen, Q; Matsugi, T | 1 |
| Champion, HC; Garrison, EA; Kadowitz, PJ | 1 |
| Amici, D; Bramucci, M; Gobbetti, A; Maccari, E; Miano, A; Murri, O; Quassinti, L; Zerani, M | 1 |
| Araki, H; Futagami, K; Gomita, Y; Kawasaki, H; Takenaga, M | 1 |
| Addison, RS; Baker, PV; Franklin, ME; Hooper, WD | 1 |
| Riva, E; Traquandi, C | 1 |
| Mineshita, S; Shimakura, K; Wang, LM; Xu, ZH; Yamamoto, T | 1 |
| Akiyoshi, K; Ito, M; Iwao, T; Nakagawa, M; Saikawa, T; Teshima, Y; Yasunaga, S; Yonemochi, H | 1 |
| Mather, TN; Ribeiro, JM | 1 |
| Danser, AH; Sassen, LM; Schalekamp, MA; van Kats, JP; van Meegen, JR; Verdouw, PD | 1 |
| Baltatu, O; Buikema, H; Ganten, D; Nishimura, H; Urata, H | 1 |
| Struthers, AD | 1 |
| Krauski, KR; Mattson, DL | 1 |
| Ashida, K; Hamano, K; Hazon, N; Takei, Y; Tierney, ML | 1 |
| Buikema, H; Ganten, D; Grandjean, JG; Oosterga, M; Pinto, YM; Rooks, G; Urata, H; van Gilst, WH; Voors, AA | 1 |
| Andrade, MC; Boim, MA; Carmona, AK; Casarini, DE; Quinto, BM; Ribas, OS; Schor, N | 1 |
| Fukumori, R; Hosokawa, H; Ibusuki, T; Kambe, T; Kubo, T; Saito, E | 1 |
| Carraway, JW; Holycross, BJ; McCune, SA; Park, S; Radin, MJ | 1 |
| Anwar, M; Ibrahim, IN; Kadowitz, PJ; Kaye, AD; Nossaman, BD; Smith, DE | 1 |
| Corvol, P; Ezan, E; Gonzales, MF; Junot, C; Menard, J; Michaud, A | 1 |
| Rauch, M; Schmid, HA | 1 |
| Binevski, PV; Gomazkov, OA; Grinshtein, SV; Kost, OA; Nikolskaya, II; Pozdnev, VF | 1 |
| Hattori, M; Hayashi, M; Katada, J; Muramatsu, M | 1 |
| Johnson, AK; McLennan, GP; Robinson, MM; Thunhorst, RL | 1 |
| Riegger, GA | 1 |
| Danser, AH; Dekkers, DH; Lamers, JM; Saris, JJ; Saxena, PR; Schalekamp, MA; van Kesteren, CA | 1 |
| Briand, R; Lamouche, S; Martineau, D; Yamaguchi, N | 1 |
| Anderson, P; Bolger, G; Jaramillo, J; Jung, G; Lamarre, D; Liard, F; Pilote, L; Simoneau, B; Thibeault, D; Vigeant, JC | 1 |
| Andersson, RG; Persson, K | 1 |
| Kamata, K; Mizutani, K | 1 |
| Danser, AH; de Vries, R; MaassenVanDenBrink, A; Saxena, PR; Schalekamp, MA | 1 |
| Chiba, S; Fukumori, R; Ibusuki, T; Kambe, T; Kubo, T | 1 |
| Danser, AH; de Vries, R; Saxena, PR; Tom, B | 1 |
| Bessou, JP; Ferry, G; Hurel-Merle, S; Lallemand, F; Richard, V; Scalbert, E; Thuillez, C | 1 |
| Johnson, AK; Schoorlemmer, GH; Thunhorst, RL | 1 |
| Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG | 1 |
| Ditiatkov, AE; Radzevich, AE; Tikhonov, VA | 1 |
| Connell, JM; Hillier, C; McDonald, JE; McMurray, JJ; Padmanabhan, N; Petrie, MC | 1 |
| Anderson, WG; Hazon, N; Takei, Y | 1 |
| Felder, RB; Wei, SG | 1 |
| Campagnole-Santos, MJ; Côrtes, SF; Lemos, VS; Santos, RA; Silva, DM | 1 |
| Diamond, LE; Logan, JS; McGregor, CG; Miller, VM; Severson, SR; Taner, CB; Ugurlu, MM; Warnecke, G | 1 |
| Kotov, AV; Obukhova, MF; Pevtsova, EI; Tolpygo, SM | 2 |
| De Zeeuw, D; Haas, M; Haverdings, RF; Meijer, DK; Moolenaar, F; Navis, G; Van Loenen-Weemaes, AM | 1 |
| Cuttle, G; Dovichi, SS; Häckl, LP; Lima-Landman, MT; Nicolau, M | 1 |
| Azizi, M; Ezan, E; Guyene, T; Hallouin, MC; Junot, C; Ménard, J | 1 |
| Buczko, W; Kucharewicz, I; Matys, T; Pawlak, D; Pawlak, R | 1 |
| Buikema, H; Grandjean, JG; Mariani, M; Oosterga, M; van Gilst, WH; Voors, AA | 1 |
| Boomsma, F; Danser, AH; Garrelds, IM; Saxena, PR; Scalbert, E; Stegmann, AP; Tom, B | 1 |
| Qui, XS; Sim, MK | 1 |
| Browne, AE; Chatterjee, K; Grossman, W; Karliner, JS; Lee, RJ; Parmley, WW; Sievers, RE; Zhu, BQ | 1 |
| Bell, PD; Fintha, A; Fuson, AL; Komlosi, P; Peti-Peterdi, J; Rosivall, L; Warnock, DG | 1 |
| Barnes, R; Speth, R | 1 |
| Geng, L; Nilsson, SF; Persson, K | 1 |
| Hagiwara, Y; Kubo, T | 1 |
| Lancien, F; Le Mével, JC; Mabin, D; Mimassi, N | 1 |
| Campagnole-Santos, MJ; de Carvalho, MH; Fernandes, L; Maia, LG; Ramos, MC; Souza dos Santos, RA | 1 |
| Castellon, R; Hamdi, HK | 1 |
| Amici, D; Bramucci, M; Maccari, E; Miano, A; Murri, O; Quassinti, L | 1 |
| Chester, AH; Hafizi, S; Yacoub, MH | 1 |
| Batenburg, WW; Danser, AH; de Bruijn, RJ; de Vries, R; Dive, V; Georgiadis, D; Tom, B; van Esch, JH; van Gool, JM; Yiotakis, A | 1 |
| Leehey, DJ; Singh, AK; Singh, R | 1 |
| Imanishi, M; Konishi, Y; Miyazaki, M; Morikawa, T; Okada, N; Okumura, M; Suzuki, H; Takai, S; Yoshioka, K | 1 |
| Chai, W; Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP | 1 |
| Becari, C; Moysés, MK; Oliveira, EB; Salgado, MC; Santos, CF; Sivieri, DO | 1 |
| Dias da Silva, VJ; Fazan Júnior, R; Montano, N; Salgado, HC | 1 |
| Butler, DG | 1 |
| Averbukh, Z; Berman, S; Cohn, M; Efrati, S; Modai, D; Rapoport, M; Weissgarten, J | 1 |
| Bertera, FM; Gironacci, MM; Höcht, C; Mayer, MA; Schuman, M; Taira, CA | 1 |
| Boulares, H; Matrougui, K; Palen, DI; Su, J | 1 |
| Assreuy, J; Fernandes, D; Silva, MA; Stulzer, HK | 1 |
| Chung, JS; Webster, SG | 1 |
| Dole, WP; Fisher, ND; Hollenberg, NK; Jan Danser, AH; Nussberger, J | 1 |
| Lu, J; Sun, L; Yu, XJ; Zang, WJ; Zhang, CH | 1 |
| Guy, JL; Rushworth, CA; Turner, AJ | 1 |
| Al-Maghrebi, M; Benter, IF; Diz, DI | 1 |
| Cox, PA; Gard, P; Gullick, DR; Ingram, MJ; Moss, GP; Pugh, WJ; Smart, JD | 1 |
| Montenegro, MF; Pessa, LR; Tanus-Santos, JE | 1 |
| de Kloet, AD; Kim, DH; Krause, EG; Sakai, RR; Seeley, RJ; Woods, SC | 1 |
| Antunes-Rodrigues, J; Araujo, IG; Coimbra, TM; Mecawi, AS; Reis, LC; Rocha, FF | 1 |
| Hou, J; Mao, C; Shi, L; Xu, Z; Zeng, F; Zhang, H | 1 |
| Dias-Junior, CA; Kanashiro, A; Montenegro, MF; Neto-Neves, EM; Spiller, F; Tanus-Santos, JE | 1 |
| Beltz, TG; Johnson, AK; Thunhorst, RL | 1 |
| Ehlers, PI; Korpela, R; Nurmi, L; Turpeinen, AM; Vapaatalo, H | 1 |
| Al-Saleh, FM; Benter, IF; Chappell, MC; Diz, DI; Raghupathy, R; Yousif, MH | 1 |
| Harty, DWS; Hunter, N | 1 |
| Ager, EI; Chan, J; Chong, WW; Christophi, C; Neo, JH; Wen, SW | 1 |
| Irigoyen, MC; Kucharski, LC; Machado, UF; Oliveira, AR; Oliveira, UO; Schaan, BD | 1 |
| Akhtar, S; Benter, IF; Dhaunsi, GS; Makki, BM; Qabazard, BA; Yousif, MH | 1 |
| Kim, JH; Kim, SH; Oh, YB; Park, BH; Park, BM | 1 |
| Chen, K; Li, J; Lu, B; Yan, J; Yang, X | 1 |
| Castro-Moreno, P; Del Valle-Mondragón, L; Hernández-Muñoz, R; Ibarra-Barajas, M; López-Guerrero, JJ; Pardo, JP; Pastelín-Hernández, G; Villalobos-Molina, R | 1 |
| Bagi, Z; Cassuto, J; Feher, A; Patel, V; Szabo, A; Vinayak Kamath, M | 1 |
| Ager, EI; Christophi, C; Neo, J; Wen, SW | 1 |
| Berry, C; Biggerstaff, F; Clarke, A; Dalzell, JR; Hillier, C; McMurray, JJ; Padmanabhan, N; Petrie, MC; Seed, A; Whelan, CJ | 1 |
| Del Valle-Mondragón, L; Echeverría-Rodríguez, O; Hong, E | 1 |
| Bányai, E; Boczán, J; Daragó, A; Édes, I; Fagyas, M; Papp, Z; Siket, IM; Tóth, A; Úri, K | 1 |
| Del Valle-Mondragón, L; Guzmán-Hernández, EA; Ibarra-Barajas, M; Pastelín-Hernández, G; Sánchez-Mendoza, MA; Villalobos-Molina, R | 1 |
| Cervantes-Pérez, LG; Del Valle-Mondragón, L; Ibarra-Lara, L; Oidor-Chan, VH; Pastelín-Hernández, GS; Pérez-Severiano, F; Ramírez-Ortega, M; Sánchez-Aguilar, M; Sánchez-Mendoza, A; Soria-Castro, E; Torres-Narváez, JC; Zarco-Olvera, G | 1 |
| An, L; Li, CS; Liu, QT; Tong, N; Xiao, HL; Yang, J; Zhao, LX | 1 |
| Korpela, R; Siltari, A; Vapaatalo, H | 1 |
| Al-Jarallah, A; Babiker, F; Joseph, S | 1 |
| Alves, PH; Castro, CH; Colugnati, DB; Macedo, LM; Mendes, EP; Nunes, AD; Pedrino, GR; Santos, RA; Souza, AP | 1 |
| Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Khattab, MM; Sabry, D | 1 |
| Andrade, MCC; Campanha-Rodrigues, AL; Casarini, DE; Costa-Neto, CM; Mortara, RA; Nogueira, MD; Parreiras-E-Silva, LT; Pereira, LM; Reis, RI | 1 |
| Gao, L; Jiang, T; Lu, JL; Tao, MX; Xue, X; Zhang, YD; Zhou, JS | 1 |
| Gao, X; Li, S; Wang, R; Wei, Z; Xu, D; Xu, H; Yang, F; Yi, X; Zhang, B; Zhang, G; Zhang, H; Zhang, L; Zhang, X; Zhang, Y; Zhu, Y | 1 |
| Arnold, AC; Barber, AJ; Dennis, MD; Dierschke, SK; Toro, AL | 1 |
| Gao, X; Ge, X; Jin, F; Li, S; Li, Y; Mao, N; Wei, Z; Xu, H; Yang, F; Yang, Y; Zhang, M; Zhang, Y | 1 |
7 review(s) available for captopril and angiotensin i
| Article | Year |
|---|---|
[Angiotensin I converting enzyme inhibitors in ischemic cardiopathy].
Topics: Angina Pectoris; Angiotensin I; Captopril; Clinical Trials as Topic; Coronary Circulation; Myocardial Infarction | 1991 |
Pharmacology of angiotensin converting enzyme inhibitors. A review.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Binding Sites; Blood Pressure; Captopril; Eating; Enalapril; Half-Life; Humans; Intestinal Absorption; Kinetics; Oligopeptides; Peptidyl-Dipeptidase A; Renin; Teprotide | 1986 |
[The renin-angiotensin system. Physiopathological aspects and clinical implications of hypertensive syndromes. A survey].
Topics: Acromegaly; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Cushing Syndrome; Glycoproteins; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Diseases; Prostaglandins; Receptors, Adrenergic; Receptors, Angiotensin; Renin; Sodium; Sympathetic Nervous System; Teprotide | 1981 |
Angiotensin II and renal hypertension in dog, rat and man: effect of converting enzyme inhibition.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dogs; Female; Furosemide; Humans; Hypertension, Renal; Male; Middle Aged; Potassium; Proline; Radioimmunoassay; Rats; Renal Artery Obstruction; Renin; Saralasin; Sodium | 1980 |
Drugs inhibiting the renin - angiotensin system.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Cardiac Output; Dogs; Hypertension; Lipids; Pepstatins; Phospholipids; Rats; Renin; Structure-Activity Relationship; Substrate Specificity | 1981 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Dogs; Hemodynamics; Hydralazine; Hydrochlorothiazide; Hypertension; Kallikreins; Kidney; Proline; Prostaglandins; Rabbits; Rats; Renin; Sodium | 1980 |
[ACE inhibitors or AT1 receptor antagonists?].
Topics: Age Factors; Aged; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Death, Sudden, Cardiac; Enalapril; Heart Failure; Humans; Losartan; Prodrugs; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Time Factors | 1999 |
19 trial(s) available for captopril and angiotensin i
| Article | Year |
|---|---|
Long-term effects of captopril (SQ14 225) on blood-pressure and hormone levels in essential hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Proline; Renin | 1979 |
Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Proline; Renin | 1979 |
[Effect of captopril on human myocardial ACE-inhibition: neurohumoral variations during coronary sinus cardioplegia. Cardioprotective effect during aortocoronary bypass].
Topics: Aged; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardioplegic Solutions; Coronary Artery Bypass; Coronary Disease; Drug Evaluation; Female; Heart Arrest, Induced; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Peptidyl-Dipeptidase A; Placebos | 1992 |
Effect of the circulating renin-angiotensin system on prolactin release in humans.
Topics: Adenoma; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Circadian Rhythm; Enalapril; Humans; Hypertension; Prolactin; Renin; Renin-Angiotensin System; Thyrotropin-Releasing Hormone | 1990 |
Hemodynamic responses to angiotensin I in normal volunteers and the antagonism by the angiotensin-converting enzyme inhibitor cilazapril.
Topics: Administration, Oral; Adolescent; Adult; Angiotensin I; Blood Pressure; Captopril; Cilazapril; Diastole; Dose-Response Relationship, Drug; Enalapril; Humans; Male; Pyridazines; Systole; Vascular Resistance | 1987 |
The assessment of ACE activity in man following angiotensin I challenges: a comparison of cilazapril, captopril and enalapril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cilazapril; Dose-Response Relationship, Drug; Enalapril; Humans; Peptidyl-Dipeptidase A; Pyridazines; Time Factors; Vascular Resistance | 1989 |
Captopril versus enalapril maleate: a comparison of antihypertensive and hormonal effects.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Dipeptides; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Potassium; Proline; Renin; Sodium; Time Factors | 1985 |
Converting enzyme inhibition in mild and moderate essential hypertension. I. Acute effects on blood pressure, the renin-angiotensin system and blood bradykinin after a single dose of captopril.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1985 |
Inhibition of angiotensin-I response by cilazapril and its time course in normal volunteers.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cilazapril; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Humans; Male; Pyridazines; Random Allocation; Time Factors | 1987 |
The renin-angiotensin system during converting enzyme inhibition with captopril in patients with severe treatment-resistant hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Blood Pressure; Captopril; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol; Renin; Renin-Angiotensin System | 1984 |
Angiotensin II formation by an alternative pathway during exercise in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Benzamidines; Blood Pressure; Bradykinin; Captopril; Cross-Over Studies; Double-Blind Method; Exercise; Guanidines; Heart Rate; Humans; Lactates; Lactic Acid; Male; Peptidyl-Dipeptidase A; Renin; Serine Proteinase Inhibitors | 1994 |
Review of studies on the clinical pharmacodynamics of cilazapril.
Topics: Administration, Oral; Aged; Angiotensin I; Blood Pressure; Captopril; Cardiac Output; Cilazapril; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Enalapril; Female; Half-Life; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol | 1994 |
Blood pressure effects of acute intravenous renin or oral angiotensin converting enzyme inhibition in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Injections, Intravenous; Male; Middle Aged; Renin; Time Factors | 1994 |
Effects of captopril on myocardial protection during cardioplegia.
Topics: Angiotensin I; Captopril; Coronary Artery Bypass; Creatine Kinase; Double-Blind Method; Epinephrine; Female; Heart Arrest, Induced; Humans; Male; Middle Aged; Myocardial Reperfusion Injury; Norepinephrine | 1993 |
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Peptide Fragments; Time Factors | 1996 |
Vasoconstrictor effect of the angiotensin-converting enzyme-resistant, chymase-specific substrate [Pro(11)(D)-Ala(12)] angiotensin I in human dorsal hand veins: in vivo demonstration of non-ace production of angiotensin II in humans.
Topics: Administration, Oral; Angina Pectoris; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Captopril; Chronic Disease; Chymases; Dose-Response Relationship, Drug; Double-Blind Method; Hand; Humans; Infusions, Intravenous; Irbesartan; Middle Aged; Peptidyl-Dipeptidase A; Reproducibility of Results; Serine Endopeptidases; Substrate Specificity; Tetrazoles; Vasoconstriction; Veins | 2001 |
Functional consequences of angiotensin-converting enzyme gene polymorphism on N-acetyl-Ser-Asp-Lys-Pro degradation and angiotensin II production.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cross-Over Studies; Female; Genotype; Homozygote; Humans; Male; Oligopeptides; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Single-Blind Method; Substrate Specificity | 2002 |
Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans.
Topics: Administration, Oral; Adult; Amides; Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Diet; Dose-Response Relationship, Drug; Female; Fumarates; Glomerular Filtration Rate; Humans; Male; Middle Aged; Natriuresis; Predictive Value of Tests; Reference Values; Renal Circulation; Renal Plasma Flow; Renin; Sodium; Sodium, Dietary; Vasodilation | 2008 |
Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity.
Topics: Aged; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Bradykinin; Captopril; Coronary Vessels; Endothelium, Vascular; Female; Gene Expression Regulation, Enzymologic; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2013 |
405 other study(ies) available for captopril and angiotensin i
| Article | Year |
|---|---|
Hyponatraemic hypertensive syndrome with renal-artery occlusion corrected by captopril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Arginine Vasopressin; Blood Pressure; Captopril; Female; Humans; Hypertension, Malignant; Hyponatremia; Middle Aged; Potassium; Proline; Renal Artery Obstruction; Renin; Syndrome | 1979 |
Mechanism of the protective effect of angiotensin-converting enzyme inhibition in hemorrhagic shock.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cats; Male; Mesenteric Arteries; Proline; Regional Blood Flow; Shock, Hemorrhagic | 1979 |
Effects of an orally active converting-enzyme inhibitor, SQ 14225, on pressor responses to angiotensin administered into the brain ventricles of spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cerebral Ventricles; Enzyme Inhibitors; Hypertension; Male; Pressoreceptors; Proline; Rats | 1979 |
Effects of angiotensin I-converting enzyme inhibitor, SQ 14225, in nomal men.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensins; Blood Pressure; Captopril; Humans; Male; Middle Aged; Proline; Renin | 1979 |
Responses of the renin-angiotensin system and kallikrein-kinin system to sodium and converting enzyme inhibitor (SQ 14,225).
Topics: Angiotensin I; Angiotensins; Animals; Bradykinin; Captopril; Diet; Kallikreins; Kinins; Male; Proline; Rats; Renin; Sodium | 1979 |
Captopril in hypertension with renal artery stenosis and in intractable hypertension; acute and chronic changes in circulating concentrations of renin, angiotensins I and II and aldosterone, and in body composition.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Proline; Renal Artery Obstruction; Renin; Sodium | 1979 |
[Effects of a single dose of captopril on blood pressure and the renin-angiotensin-aldosterone system in normal subjects and hypertensive patients with various etiologies (author's transl)].
Topics: Adult; Aldosterone; Angiotensin I; Angiotensins; Blood Pressure; Captopril; Humans; Hypertension; Male; Proline; Renin | 1979 |
Effect of captopril on the release of the components of the renin-angiotensin system into plasma and lymph.
Topics: Angiotensin I; Angiotensin II; Animals; Capillary Resistance; Captopril; Dehydration; Denervation; Dogs; Glomerular Filtration Rate; Kidney Transplantation; Lymph; Peptidyl-Dipeptidase A; Renal Circulation; Renin; Renin-Angiotensin System; Sodium Chloride; Transplantation, Heterotopic | 1992 |
Increased vascular formation of angiotensin II in one-kidney, one clip hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood Vessels; Captopril; Enalapril; Hypertension, Renovascular; In Vitro Techniques; Male; Mesenteric Arteries; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Reference Values; Saralasin | 1992 |
The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Captopril; Chlorides; CHO Cells; Cricetinae; Enalapril; Enalaprilat; Humans; Indoles; Kinetics; Lisinopril; Mutation; Peptidyl-Dipeptidase A | 1992 |
Evidence for two binding sites on membrane-bound angiotensin-converting enzymes (ACE) for exogenous inhibitors except in testis.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Brain; Captopril; Cell Membrane; Indoles; Lung; Male; Peptidyl-Dipeptidase A; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Testis | 1992 |
Relation between inhibition of renal angiotensin II production and hemodynamic effect of captopril in anesthetized rabbit.
Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rabbits; Renal Circulation; Renin-Angiotensin System; Sodium, Dietary; Tetrazoles | 1992 |
Comparison of angiotensin-converting enzyme inhibitors in the rat in perfused hindlimbs and in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dipeptides; Dose-Response Relationship, Drug; Hemodynamics; Hindlimb; Lisinopril; Male; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred SHR; Vascular Resistance | 1992 |
Pharmacology of idrapril: a new class of angiotensin converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Captopril; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hydroxylamines; Hypertension; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Substance P | 1992 |
Vasoconstrictive effects of angiotensin I and II in cat femoral arteries. Role of endothelium.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cats; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Saralasin; Vasoconstriction | 1992 |
Lack of correlation between the acute haemodynamic response to intravenous captopril and plasma concentrations of angiotensin II in patients with chronic cardiac failure.
Topics: Aged; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Cardiac Output; Cardiomyopathy, Dilated; Coronary Disease; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Vascular Resistance | 1992 |
Thirst and brain angiotensin in cattle.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Water; Brain; Bridged Bicyclo Compounds; Captopril; Cattle; Cerebrospinal Fluid; Dehydration; Eating; Female; Injections, Intraventricular; Ramipril; Thirst | 1992 |
Captopril inhibits angiotensin I-induced coronary flow reduction in isolated rat heart but has no effect on contractility or energy metabolism.
Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Animals; Captopril; Coronary Circulation; Coronary Disease; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Vasoconstriction | 1992 |
Effects of angiotensin II and angiotensin converting enzyme inhibitors on contractile and growth responses in isolated carotid arteries of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carotid Arteries; DNA; Enalapril; In Vitro Techniques; Lisinopril; Male; Rats; Rats, Inbred WKY; Vasoconstriction | 1991 |
Hemodynamic effects of benazepril, an angiotensin-converting enzyme inhibitor, as studied in conscious normotensive dogs.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Captopril; Dogs; Hemodynamics; Male; Peptidyl-Dipeptidase A | 1991 |
Direct effects in vivo of angiotensins I and II on the canine sinus node.
Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Heart Rate; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Saralasin; Sinoatrial Node; Vagotomy | 1991 |
Substrate-dependent angiotensin II formation in the peripheral circulation.
Topics: Angiotensin I; Angiotensin II; Animals; Aprotinin; Captopril; Chromatography, High Pressure Liquid; Chymotrypsin; Male; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin; Substrate Specificity | 1990 |
Angiotensin-converting activity of tissue kallikrein.
Topics: Angiotensin I; Angiotensin II; Animals; Aprotinin; Captopril; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Kallikreins; Rats | 1990 |
Hemodynamic effects of bradykinin on systemic and pulmonary circulation in healthy and hypertensive humans.
Topics: Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Cardiac Output; Enalapril; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Lisinopril; Male; Middle Aged; Pulmonary Circulation; Vascular Resistance | 1990 |
In vivo evaluation of the antagonist activity of angiotensin I analogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Biphenyl Compounds; Captopril; Imidazoles; Losartan; Lung; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Tetrazoles | 1992 |
Angiotensin I and II disappear completely from circulating blood within 48 hours after binephrectomy: improved measurement of angiotensins in rat plasma.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Chromatography, High Pressure Liquid; Diet, Sodium-Restricted; Hypertension, Renal; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renin; Time Factors | 1991 |
Regional production of angiotensins I and II: contribution of vascular kidney-derived renin.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Female; Furosemide; Head; Kidney; Lung; Muscles; Myocardium; Renin; Skin; Swine | 1991 |
Local generation of angiotensin II as a mechanism of aldosterone secretion in rat adrenal capsules.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Enalapril; Female; In Vitro Techniques; Lisinopril; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1991 |
The two homologous domains of human angiotensin I-converting enzyme are both catalytically active.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Captopril; Catalysis; Chlorides; Cricetinae; Cricetulus; DNA Mutational Analysis; Enalaprilat; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Structure-Activity Relationship | 1991 |
Angiotensin II generation in the rat vena cava: stimulation of local synthesis by beta-adrenoceptor activation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Female; Guinea Pigs; Heart Atria; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Renin-Angiotensin System; Saralasin; Trachea; Tritium; Vena Cava, Superior | 1991 |
Response of urinary angiotensin to challenges of the renin-angiotensin system.
Topics: Adult; Angiotensin I; Angiotensin II; Captopril; Enalapril; Female; Furosemide; Humans; Immersion; Indomethacin; Male; Renin; Renin-Angiotensin System; Sodium, Dietary | 1991 |
Evidence in the sheep for an interaction between systemic angiotensin II and cerebral angiotensinergic mechanisms.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Captopril; Carotid Arteries; Drinking Behavior; Hydrocortisone; Injections, Intra-Arterial; Injections, Intraventricular; Sheep | 1991 |
The hemodynamic effects of S-nitrosocaptopril in anesthetized dogs.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dogs; Drug Tolerance; Female; Male; Nitroglycerin | 1991 |
Interaction of bradykinin and angiotensin in the regulation of blood pressure in conscious rats.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Drug Interactions; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Saralasin | 1991 |
Vascular production and regulation of angiotensin.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Captopril; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renin | 1991 |
Effect of captopril on congestive heart failure.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Captopril; Epinephrine; Female; Half-Life; Heart Failure; Humans; Male; Metabolic Clearance Rate; Middle Aged; Norepinephrine; Renin | 1990 |
Does endocardial endothelium mediate positive inotropic response to angiotensin I and angiotensin II?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cats; Cyclooxygenase Inhibitors; Endocardium; Endothelium; In Vitro Techniques; Microscopy, Electron; Microscopy, Electron, Scanning; Myocardial Contraction | 1990 |
Endothelial renin-angiotensin pathway. Adrenergic regulation of angiotensin secretion.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Atenolol; Captopril; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Endothelium, Vascular; Isoproterenol; Phenylephrine; Propanolamines; Radioimmunoassay; Receptors, Adrenergic, beta; Renin-Angiotensin System | 1990 |
Angiotensin II-forming pathways in normal and failing human hearts.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Captopril; Cardiac Output, Low; Female; Glycine max; Heart; Heart Ventricles; Humans; Male; Middle Aged; Myocardium; Peptidyl-Dipeptidase A; Reference Values; Trypsin Inhibitors | 1990 |
Characterization of angiotensin I-converting enzyme (ACE)-containing follicles in the rat ovary during the estrous cycle and effects of ACE inhibitor on ovulation.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Captopril; Cell Membrane; Chorionic Gonadotropin; Dipeptides; Estrus; Female; Follicle Stimulating Hormone; Granulosa Cells; Iodine Radioisotopes; Ovarian Follicle; Ovary; Ovulation; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1990 |
The role of tissue renin-angiotensin systems in hypertension and effects of chronic converting-enzyme inhibition.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Captopril; Enalapril; Gene Expression Regulation; Heart; Hydralazine; Hypertension; Isoquinolines; Kidney; Lisinopril; Male; Quinapril; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrahydroisoquinolines | 1990 |
Inhibition of neurotransmission by angiotensin I and II in rabbit isolated ear artery.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Captopril; Ear; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Regional Blood Flow; Saralasin; Synaptic Transmission | 1990 |
Effect of angiotensins on electrogenic anion transport in monolayer cultures of rat epididymis.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Anions; Captopril; Cells, Cultured; Cyclic AMP; Electron Transport; Epididymis; Male; Peptidyl-Dipeptidase A; Rats | 1990 |
The role of angiotensin-converting enzyme in the rat epididymis.
Topics: Angiotensin I; Angiotensin II; Animals; Body Fluids; Captopril; Epididymis; Fertility; Male; Orchiectomy; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1990 |
Angiotensin II-producing proteases from granulomatous tissue reaction in mice infected with Schistosoma mansoni.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Carboxypeptidases; Carboxypeptidases A; Chromatography, High Pressure Liquid; Granuloma; Hydrolases; Hydrolysis; Kinetics; Liver Diseases, Parasitic; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Peptidyl-Dipeptidase A; Schistosomiasis mansoni; Substrate Specificity | 1990 |
Angiotensins and the failing heart. Enhanced positive inotropic response to angiotensin I in cardiomyopathic hamster heart in the presence of captopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Captopril; Cardiac Output, Low; Cardiomyopathies; Cricetinae; Drug Synergism; Heart; Male; Mesocricetus; Myocardial Contraction; Myocardium; Receptors, Angiotensin | 1990 |
Synthesis and pharmacological screening of new angiotensin converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Availability; Blood Pressure; Bradykinin; Captopril; Chemical Phenomena; Chemistry; Enalapril; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains | 1990 |
Increased brainstem angiotensin-I levels in chronic 2 KIC hypertensive rats.
Topics: Angiotensin I; Animals; Brain Stem; Captopril; Hypertension, Renovascular; Male; Rats; Rats, Inbred Strains | 1990 |
Metabolism of tetradecapeptide, angiotensinogen and angiotensin I and II by isolated perfused rat hindlimbs.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Cattle; Hindlimb; Kidney; Nephrectomy; Pepstatins; Perfusion; Rats; Renin; Vasoconstrictor Agents | 1990 |
Vasopressor and depressor effects of native angiotensins and inhibition of these effects in the Japanese quail.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cardiovascular Physiological Phenomena; Cardiovascular System; Coturnix; Eels; Heart Rate; Humans; Kinetics; Male; Molecular Sequence Data; Quail; Species Specificity | 1990 |
Components of the angiotensin system cause release of a neutrophil chemoattractant from cultured bovine and human endothelial cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Bradykinin; Captopril; Cattle; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Endothelium, Vascular; Humans; In Vitro Techniques; Interleukin-8; Neutrophils; Pulmonary Artery; Renin-Angiotensin System; Saralasin; Umbilical Veins | 1990 |
Inhibitory effects of kinins on angiotensin I conversion in the local circulation.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Hindlimb; Hydrolysis; Kinetics; Kinins; Male; Perfusion; Rats; Rats, Inbred Strains | 1990 |
Cardiac angiotensinogen and its local activation in the isolated perfused beating heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Dexamethasone; Female; Heart; In Vitro Techniques; Myocardium; Perfusion; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1990 |
Noninvasive blood pressure monitoring at the finger for studying short lasting pressor responses in man.
Topics: Adult; Angiotensin I; Blood Pressure; Blood Pressure Determination; Captopril; Fingers; Heart Rate; Humans; Male; Monitoring, Physiologic; Pressoreceptors; Time Factors | 1990 |
Enhanced reactivity to bradykinin, angiotensin I and the effect of captopril in the pulmonary vasculature of chronically hypoxic rats.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Chronic Disease; Dose-Response Relationship, Drug; Hypoxia; Male; Pulmonary Artery; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1990 |
Modulation of noradrenaline release from rat cortical kidney slices: effects of angiotensin I and II.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Kidney Cortex; Norepinephrine; Rats; Rats, Inbred Strains; Saralasin; Tetrodotoxin | 1990 |
In vivo comparison of renal and femoral vascular sensitivity and local angiotensin generation.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Femoral Artery; Femoral Vein; Hemodynamics; Male; Nephrectomy; Rabbits; Renal Circulation; Renin; Renin-Angiotensin System | 1990 |
Effect of chronic enalapril treatment on enzymes responsible for the catabolism of angiotensin I and formation of angiotensin II.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Carboxypeptidases; Chromatography, High Pressure Liquid; Enalapril; Kidney; Neprilysin; Oligopeptides; Peptide Fragments; Peptides; Rats; Rats, Inbred WKY; Thiorphan | 1990 |
Mechanisms of captopril-induced potentiation of the depressor responses to arachidonic acid in rats.
Topics: Angiotensin I; Animals; Antihypertensive Agents; Aprotinin; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Injections, Intra-Arterial; Injections, Intravenous; Male; Rats; Rats, Inbred Strains | 1986 |
Effect of angiotensin converting enzyme inhibitors on the vasoconstrictor action of angiotensin I on isolated rat kidney.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; In Vitro Techniques; Kidney; Kinetics; Male; Peptidyl-Dipeptidase A; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Vasoconstrictor Agents | 1986 |
Analysis of influence of extra- and intrarenally formed angiotensin II on renal blood flow.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Male; Rabbits; Regional Blood Flow; Renal Circulation | 1986 |
Contractile effects of tetradecapeptide renin substrate on rat femoral resistance vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aprotinin; Captopril; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Vascular Resistance | 1987 |
Peripheral hemodynamic and humoral effects of oral zofenopril calcium (SQ. 26,991) in patients with congestive heart failure.
Topics: Administration, Oral; Aged; Angiotensin I; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Captopril; Female; Forearm; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Renin; Vasodilation; Veins | 1989 |
Kinetic studies of the pharmacologic response to captopril in rats. I. Role of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension, Renovascular; Infusions, Intravenous; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sodium | 1989 |
The renin-angiotensin system during pregnancy in chronically instrumented, conscious rats.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Drug Synergism; Enalaprilat; Female; Glomerular Filtration Rate; Hemodynamics; Norepinephrine; Postpartum Period; Pregnancy; Pregnancy, Animal; Rats; Renal Circulation; Renin; Renin-Angiotensin System; Vasoconstriction | 1989 |
The captopril glomerular filtration rate renogram in renovascular hypertension.
Topics: Adult; Aged; Angiotensin I; Blood Pressure; Captopril; Catecholamines; Clonidine; Diagnosis, Differential; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renovascular; Kidney; Middle Aged; Organometallic Compounds; Pentetic Acid; Radioisotope Renography; Renin; Technetium Tc 99m Pentetate | 1989 |
S-nitrosocaptopril. II. Effects on vascular reactivity.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cattle; Coronary Vessels; Drug Interactions; Femoral Artery; In Vitro Techniques; Methylene Blue; Saralasin; Vasodilator Agents | 1989 |
Effects of renin inhibition in the conscious primate Macaca fascicularis.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Furosemide; Heart Rate; Macaca mulatta; Oligopeptides; Osmolar Concentration; Renin; Structure-Activity Relationship | 1989 |
Angiotensin formation in the isolated rat hindlimb.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Hindlimb; In Vitro Techniques; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin; Vasoconstriction | 1989 |
Direct evidence for local generation and release of angiotensin II in human vascular tissue.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Captopril; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Pregnancy; Umbilical Veins | 1989 |
Facilitation of noradrenaline release by isoprenaline in rat isolated atria does not involve angiotensin II formation.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cocaine; Electric Stimulation; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Saralasin | 1989 |
In vivo production of plasma angiotensin I: is plasma renin sufficient?
Topics: Adult; Aged; Angiotensin I; Captopril; Humans; Hypertension; Infusions, Intravenous; Iodine Radioisotopes; Middle Aged; Renin; Tissue Distribution | 1989 |
Effects of teprotide, captopril and enalaprilat on arterial wall kininase and angiotensin converting activity.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Enalapril; Enalaprilat; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Teprotide | 1987 |
Stimulation by angiotensins I and II of ACTH release from goldfish pituitary cell columns.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenocorticotropic Hormone; Angiotensin I; Angiotensin II; Animals; Captopril; Cells, Cultured; Cyprinidae; Female; Goldfish; In Vitro Techniques; Male; Pituitary Gland, Anterior; Saralasin | 1987 |
Protective effects of captopril and enalapril on myocardial ischemia and reperfusion damage of rat.
Topics: Angiotensin I; Animals; Captopril; Coronary Circulation; Coronary Disease; Enalapril; Epoprostenol; Female; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Infarction; Rats | 1987 |
Effects of angiotensin I converting enzyme (ACE) related substances upon the vascular prostacyclin generation.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Humans; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY | 1987 |
[Direct cardiac effects of angiotensins I and II and 2 converting enzyme inhibitors (captopril and perindopril). Indirect demonstration of a converting enzyme in the rat heart].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Coronary Circulation; Coronary Disease; Heart; Heart Rate; Indoles; Male; Myocardium; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Saralasin | 1988 |
Effect of captopril on the bradykinin-induced release of prostacyclin from guinea-pig lungs and bovine aortic endothelial cells.
Topics: Angiotensin I; Animals; Aorta; Biological Factors; Bradykinin; Captopril; Cattle; Endothelium, Vascular; Epoprostenol; Guinea Pigs; In Vitro Techniques; Lung; Nitric Oxide; Peptidyl-Dipeptidase A | 1988 |
Comparison of the effects of the dipeptidyl peptidase inhibitors captopril, ramipril, and enalapril on water intake and sodium appetite of Sprague-Dawley rats.
Topics: Angiotensin I; Angiotensin II; Animals; Appetite; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Captopril; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Drinking; Enalapril; Ramipril; Rats; Rats, Inbred Strains; Renin; Sodium Chloride | 1988 |
Facilitation of noradrenaline release from sympathetic nerves in rat anococcygeus muscle by activation of prejunctional beta-adrenoceptors and angiotensin receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Desipramine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Muscles; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Angiotensin; Saralasin; Sympathetic Nervous System | 1988 |
Conversion of kinins and their antagonists into B1 receptor activators and blockers in isolated vessels.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Animals; Blood Vessels; Bradykinin; Captopril; Dogs; Endothelium; In Vitro Techniques; Kinins; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter | 1986 |
Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Captopril; Catecholamines; Disease Models, Animal; Dogs; Epinephrine; Hexamethonium; Hexamethonium Compounds; Hypertension, Malignant; Hypertension, Renovascular; Neuropeptides; Norepinephrine; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1987 |
Intrarenal generation of angiotensin II evaluated by an electrophysiological technique.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Bridged Bicyclo Compounds; Captopril; Female; Hydronephrosis; Juxtaglomerular Apparatus; Kidney; Membrane Potentials; Mice; Ramipril; Renin | 1987 |
[Effects of conversion enzyme inhibitors on the synthesis of angiotensin II by the isolated rat kidney].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bridged Bicyclo Compounds; Captopril; Kidney; Male; Ramipril; Rats; Rats, Inbred Strains | 1987 |
A cardiac specific analog of angiotensin I potentiated by converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Drug Synergism; Myocardial Contraction; Sheep; Structure-Activity Relationship | 1985 |
[Acute and long-term effect of captopril in severe chronic heart failure].
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Captopril; Chronic Disease; Drug Evaluation; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Proline; Time Factors | 1985 |
Angiotensin and converting enzyme regulate extrarenal salt excretion in ducks.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood; Blood Pressure; Captopril; Diuresis; Dopamine; Ducks; Epinephrine; Hypertonic Solutions; Nasal Mucosa; Norepinephrine; Osmolar Concentration; Peptidyl-Dipeptidase A; Salt Gland; Sodium Chloride | 1985 |
[Drugs that block the angiotensin converting enzyme].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Drug Administration Schedule; Enalapril; Humans; Hypertension; Kidney; Kidney Glomerulus | 1985 |
Captopril in the hepatorenal syndrome.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Female; Humans; Iodine Radioisotopes; Kidney Diseases; Liver Diseases; Male; Middle Aged; Radioimmunoassay; Renin; Sodium; Syndrome | 1985 |
Evidence for a captopril-sensitive angiotensin converting enzyme in the hindquarter vasculature of SHR and WKY.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Hindlimb; Hypertension; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Vascular Resistance | 1985 |
Synthesis and pharmacology of the potent angiotensin-converting enzyme inhibitor N-[1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl-(S)-pyroglutamic acid.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Chemical Phenomena; Chemistry; Diet, Sodium-Restricted; Dipeptides; Enalapril; Heart Rate; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Inbred SHR | 1985 |
Angiotensin peptides stimulate phosphoinositide breakdown and prolactin release in anterior pituitary cells in culture.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Cells, Cultured; Female; Inositol Phosphates; Kinetics; Phosphatidylinositols; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin | 1986 |
Pharmacokinetic studies on pharmacologic response of captopril in rats.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Kinetics; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Sodium | 1985 |
Haemodynamic and humoral effects of lower body negative pressure in normal, sodium-replete man during angiotensin-converting enzyme inhibition with captopril.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arginine Vasopressin; Captopril; Epinephrine; Hemodynamics; Humans; Lower Body Negative Pressure; Male; Norepinephrine; Renin; Renin-Angiotensin System; Sodium | 1986 |
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin I; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Dinoprostone; Dogs; Hypertension; Hypertension, Renovascular; Kallikreins; Male; Peptidyl-Dipeptidase A; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Water-Electrolyte Balance | 1986 |
Inhibition of angiotensin-converting enzyme by des-Leu10-angiotensin I: a potential mechanism of endogenous angiotensin-converting enzyme regulation.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Bradykinin; Captopril; Humans; Kinetics; Lung; Peptidyl-Dipeptidase A; Rabbits | 1986 |
Prostacyclin generation by cultured human vascular endothelial cells with reference to angiotensin I-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Vessels; Bradykinin; Captopril; Cells, Cultured; Endothelium; Enzyme Activation; Epoprostenol; Humans; Peptidyl-Dipeptidase A | 1986 |
Rapid affinity chromatographic purification of human lung and kidney angiotensin-converting enzyme with the novel N-carboxyalkyl dipeptide inhibitor N-[1(S)-carboxy-5-aminopentyl]glycylglycine.
Topics: Angiotensin I; Captopril; Chlorides; Chromatography, Affinity; Dipeptides; Humans; Hydrogen-Ion Concentration; Kidney; Kinetics; Lung; Peptidyl-Dipeptidase A | 1986 |
Converting enzyme activity of free airway cells.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Female; Guinea Pigs; Macrophages; Male; Peptidyl-Dipeptidase A; Protease Inhibitors; Pulmonary Alveoli | 1986 |
Liver angiotensinogen synthesis and release during captopril treatment in sodium-depleted rats.
Topics: Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Renin; Sodium | 1987 |
Biological activities of sarcosine1-angiotensin I in man.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Infusions, Intravenous; Male; Peptidyl-Dipeptidase A; Renin; Substrate Specificity | 1986 |
Induction by fibroblast growth factor of angiotensin converting enzyme in vascular endothelial cells in vitro.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Captopril; Cells, Cultured; Edetic Acid; Endothelium; Enzyme Induction; Fibroblast Growth Factors; Growth Substances; Kinetics; Peptidyl-Dipeptidase A; Swine | 1987 |
Enzymatic formation of angiotensins II and III in the hindlimb circulation of dogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Captopril; Dogs; Epinephrine; Female; Hindlimb; Iliac Artery; Male; Peptidyl-Dipeptidase A; Vasoconstriction | 1987 |
No substrate specificity of converting enzyme for N-terminal substituted angiotensin I in man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Male; Substrate Specificity | 1987 |
Regulation of prostacyclin generation by angiotensin converting enzyme related substances in cultured human vascular endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cells, Cultured; Endothelium; Epoprostenol; Humans; Peptidyl-Dipeptidase A | 1987 |
Hypotensive effect of SA446, an angiotensin converting enzyme inhibitor, in 2-kidney, 1-clip renal hypertensive and normotensive dogs.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dogs; Female; Hypertension, Renal; Male; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Sulfhydryl Compounds; Thiazolidines | 1987 |
Metabolism of bradykinin and angiotensin I by human basilar artery and rabbit aorta.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Basilar Artery; Bradykinin; Captopril; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Lysine Carboxypeptidase; Male; Muscle, Smooth, Vascular; Phenanthrolines; Rabbits | 1987 |
Thirst in Brattleboro rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Crosses, Genetic; Drinking Behavior; Heterozygote; Homozygote; Isoproterenol; Male; Nephrectomy; Rats; Rats, Brattleboro; Rats, Inbred Strains; Rats, Mutant Strains; Saline Solution, Hypertonic; Sodium; Species Specificity; Thirst | 1988 |
Systemic effects resulting from topical ocular administration of SCH 33861, a novel ACE inhibitor ocular hypotensive agent.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Heart Rate; Intraocular Pressure; Male; Phenylbutyrates; Rabbits; Spiro Compounds | 1988 |
Bradykinin-potentiating activity of captopril disulphide dimer (SQ 14,551).
Topics: Anesthesia; Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Time Factors | 1988 |
The renin-angiotensin system and treatment of heart failure.
Topics: Angiotensin I; Captopril; Heart Failure; Hemodynamics; Humans; Myocardial Contraction; Renin-Angiotensin System; Sodium | 1988 |
Cyclic (hydroxyphosphinyl)acyl dipeptides: a new class of angiotensin converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dipeptides; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Peptides, Cyclic; Rats; Structure-Activity Relationship | 1988 |
Mechanisms of hyperkalemia in systemic lupus erythematosus.
Topics: Adult; Aldosterone; Angiotensin I; Bicarbonates; Captopril; Chlorides; Enzyme Precursors; Female; Furosemide; Humans; Hyperkalemia; Lupus Erythematosus, Systemic; Male; Middle Aged; Potassium; Renin; Stimulation, Chemical | 1988 |
Enhancement of water intake by captopril (SQ14225), an angiotensin I-converting enzyme inhibitor, in the goldfish, Carassius auratus.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cyprinidae; Dose-Response Relationship, Drug; Drinking Behavior; Female; Goldfish; Male | 1988 |
Des-Leu angiotensin I: biosynthesis and drinking response.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Captopril; Carboxypeptidases; Cattle; Drinking; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Saralasin; Synaptosomes | 1988 |
Differential pressor and renal vascular reactivity to angiotensin II in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Species Specificity | 1987 |
Effect of captopril on angiotensin II release from vascular tissues in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Captopril; Hindlimb; Male; Nephrectomy; Rats; Rats, Inbred Strains | 1987 |
Inactive renin and aldosterone in Bartter's syndrome.
Topics: Adolescent; Aldosterone; Amiloride; Angiotensin I; Angiotensinogen; Animals; Bartter Syndrome; Captopril; Child; Child, Preschool; Enzyme Precursors; Female; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; In Vitro Techniques; Male; Renin; Sheep | 1987 |
Characterization of a vasopressor substance generated in human plasma by incubation.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Assay; Blood; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Hot Temperature; Humans; Isoflurophate; Pronase; Rats | 1986 |
Renal handling of angiotensins I and II in patients with renovascular hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensins; Captopril; Female; Humans; Hypertension, Renovascular; Kidney; Male; Middle Aged; Renin | 1986 |
Effect of low doses of angiotensin II perfusion on the hypotensive action of captopril in anaesthetized normotensive and spontaneously hypertensive rats.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Catecholamines; Heart Rate; Hypertension; Injections, Intravenous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1986 |
Central renin-angiotensin system and the pathogenesis of DOCA-salt hypertension in rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Desoxycorticosterone; Diuresis; Drinking; Hematocrit; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Pressoreceptors; Rats; Rats, Inbred WKY; Reflex; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride; Vasopressins | 1986 |
Role of mineralocorticoids and glucocorticoids in blood pressure regulation in normotensive rats.
Topics: Adrenalectomy; Aldosterone; Angiotensin I; Animals; Blood Pressure; Body Weight; Captopril; Corticosterone; Dexamethasone; Electrolytes; Male; Rats; Rats, Inbred Strains; Renin | 1986 |
Effects of captopril and bradykinin on arterial pressure in rats with mestranol-induced hypertension.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Female; Hypertension; Mestranol; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1986 |
Blood pressure homeostasis in the snake, Ptyas korros.
Topics: Angiotensin I; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Drug Interactions; Homeostasis; Male; Norepinephrine; Phentolamine; Snakes; Vasotocin | 1986 |
Pre- and postsynaptic effects of angiotensins in the femoral artery of spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Animals; Captopril; Dinoprost; Endothelium; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandins F; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Yohimbine | 1987 |
The role of the renin-angiotensin system in normotensive and hypertensive rats with varying renin status.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Captopril; Hypertension; Hypertension, Renal; Kidney Cortex; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renal Artery; Renin; Renin-Angiotensin System; Urethane | 1987 |
Conversion of angiotensin I to angiotensin II in the human foetoplacental vascular bed.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Blood Pressure; Captopril; Female; Humans; In Vitro Techniques; Placenta; Pregnancy; Saralasin; Vasoconstriction | 1985 |
A transition-state analogue inhibitor of human renin (H.261): test in vitro and a comparison with captopril in the anaesthetized baboon.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Female; Papio; Renin; Structure-Activity Relationship; Substrate Specificity | 1985 |
Effect of intracoronary captopril on coronary blood flow and regional myocardial function in dogs.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Heart; Hemodynamics; Male; Proline | 1985 |
A role for the adrenal renin-angiotensin system in the regulation of potassium-stimulated aldosterone production.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Captopril; Culture Techniques; Male; Potassium; Rats; Rats, Inbred Strains; Renin; Sodium | 1985 |
Captopril mediated decrease of aortic regurgitation.
Topics: Angiotensin I; Angiotensin II; Aortic Valve Insufficiency; Blood Pressure; Captopril; Heart Rate; Humans; Radioimmunoassay; Stroke Volume | 1985 |
[Dynamic evaluation of the renin-angiotensin system with captopril in screening for renovascular hypertension].
Topics: Adult; Aged; Angiotensin I; Captopril; Female; Humans; Hypertension, Renovascular; Male; Middle Aged; Nephrectomy; Radiography; Renal Artery; Renin; Renin-Angiotensin System | 1985 |
Bovine and human endothelial cell production of neutrophil chemoattractant activity in response to components of the angiotensin system.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Cattle; Cells, Cultured; Chemotaxis, Leukocyte; Diethylcarbamazine; Dose-Response Relationship, Drug; Endothelium; Humans; Indomethacin; Neutrophils; Saralasin | 1985 |
Blockade of the pressor response to angiotensins I and II in the bullfrog, Rana catesbeiana.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Norepinephrine; Phenoxybenzamine; Pulse; Rana catesbeiana; Structure-Activity Relationship | 1985 |
Effects of angiotensin I and II and their interactions with some prostanoids in perfused human umbilical arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Captopril; Drug Interactions; Female; Humans; In Vitro Techniques; Indomethacin; Perfusion; Pregnancy; Prostaglandins; Saralasin; Umbilical Arteries; Vasoconstriction | 1985 |
Effect of SQ20881 and captopril on pulmonary angiotensin II formation and blood pressure.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Female; Lung; Male; Oligopeptides; Proline; Teprotide | 1983 |
Comparative effects of enalapril, enalaprilic acid and captopril in blocking angiotensin I-induced pressor and dipsogenic responses in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Drug Evaluation, Preclinical; Enalapril; Enalaprilat; Hypertension; Male; Pressoreceptors; Proline; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Thirst; Time Factors | 1984 |
The influence of ACE-inhibition by captopril on renal formation and metabolism of angiotensins I and II in patients with renovascular hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Captopril; Catheterization; Female; Femoral Artery; Humans; Hypertension, Renovascular; Kidney; Male; Middle Aged; Proline; Renal Veins | 1984 |
Hormonal and metabolic effects of angiotensin converting enzyme inhibitors. Possible differences between enalapril and captopril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Enalapril; Humans; Hypertension; Kinins; Posture; Potassium; Proline; Prostaglandins; Renin; Renin-Angiotensin System; Sodium | 1984 |
Angiotensin I-converting enzyme in amniotic fluid.
Topics: Adult; Amniotic Fluid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Bradykinin; Captopril; Cross Reactions; Female; Humans; Hydrolysis; Immune Sera; In Vitro Techniques; Peptidyl-Dipeptidase A; Pregnancy; Radioimmunoassay; Renin | 1984 |
Effects of converting enzyme inhibitors on renin-angiotensin system in normal rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Kinetics; Lung; Male; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sulfhydryl Compounds; Thiazolidines | 1984 |
Pharmacological properties of the new orally active angiotensin converting enzyme inhibitor 2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl] -(1S,3S,5S)-2-azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498).
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Captopril; Dipeptides; Dogs; Enalapril; Male; Ramipril; Rats; Rats, Inbred Strains; Species Specificity | 1984 |
Chronic captopril infusion in two-kidney, one clip rats with normal plasma renin concentration.
Topics: Angiotensin I; Angiotensins; Animals; Blood Pressure; Captopril; Hypertension, Renovascular; Male; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains; Renin | 1984 |
Mechanism of the pressor response to tetradecapeptide renin substrate in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Male; Nephrectomy; Pepstatins; Peptides; Phenylephrine; Rats; Rats, Inbred SHR; Renin | 1984 |
Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Female; Hypertension; Male; Nephrectomy; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tissue Distribution | 1984 |
Biochemical monitoring of vasoactive peptides during angiotensin converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cross Reactions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Peptidyl-Dipeptidase A; Radioimmunoassay; Renin | 1983 |
[Efficacy of captopril in periarteritis nodosa with arterial hypertension and renal failure (author's transl)].
Topics: Angiotensin I; Captopril; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Polyarteritis Nodosa; Proline; Renin | 1981 |
Involvement of the vascular renin-angiotensin system in beta adrenergic receptor-mediated facilitation of vascular neurotransmission in spontaneously hypertensive rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenergic beta-Antagonists; Angiotensin I; Animals; Blood Pressure; Blood Vessels; Captopril; Electric Stimulation; Hypertension; Isoproterenol; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Renin-Angiotensin System; Synaptic Transmission | 1984 |
Effect of chronic treatment with captopril on reactivity of aortic smooth muscle from normotensive and renal hypertensive rats.
Topics: Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Body Weight; Captopril; Female; Hypertension, Renal; Isoproterenol; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Organ Size; Phenylephrine; Potassium Chloride; Proline; Rats; Rats, Inbred Strains | 1983 |
Analysis of the mechanism of acute decrease of blood pressure induced by captopril (SQ 14,225) in dogs by the use of aprotinin, SAR1-ILE8-angiotensin II and indomethacin.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Animals; Aprotinin; Blood Pressure; Bradykinin; Captopril; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Indomethacin; Male; Proline | 1981 |
Angiotensin I converting enzyme activity in portal vein studied in normotensive rats and in models of primary and secondary hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Hypertension; Male; Muscle, Smooth, Vascular; Oligopeptides; Portal Vein; Rats; Rats, Inbred Strains; Teprotide | 1981 |
Relationship between angiotensin I blockade and antihypertensive properties of single doses of MK-421 and captopril in spontaneous and renal hypertensive rats.
Topics: Angiotensin I; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Enalapril; Hypertension; Hypertension, Renal; Oligopeptides; Proline; Rats; Rats, Inbred Strains; Teprotide | 1981 |
A new potent inhibitor of converting enzyme: (2R,4R)-2-(2-hydroxyphenyl)-3-(3-mercaptopropionyl)-4-thiazolidinecarboxylic acid(SA446).
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Guinea Pigs; Hypertension; Ileum; In Vitro Techniques; Male; Muscle Contraction; Oligopeptides; Sulfhydryl Compounds; Teprotide; Thiazolidines | 1981 |
Effects of SQ 20881 and captopril on mesenteric, renal, and iliac vasculatures.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Female; Iliac Artery; Iliac Vein; Male; Mesenteric Arteries; Mesenteric Veins; Oligopeptides; Proline; Regional Blood Flow; Renal Circulation; Teprotide | 1983 |
Kallikrein potentiation of angiotensin I-induced contraction on isolated mesenteric artery.
Topics: Angiotensin I; Angiotensins; Animals; Bradykinin; Captopril; Drug Synergism; Kallikreins; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Saralasin; Swine; Teprotide | 1983 |
Effects of captopril (SQ 14, 225) on the renin-angiotensin-aldosterone system in normal rats.
Topics: Aldosterone; Angiotensin I; Animals; Captopril; Electrolytes; Female; Hydrocortisone; Kidney; Lung; Peptidyl-Dipeptidase A; Proline; Rats; Renin; Time Factors | 1980 |
Hormonal responses to angiotensin blockade. Comparison between receptor antagonism and converting enzyme inhibition.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin | 1980 |
Usefulness of orally active angiotensin I converting enzyme inhibitor (SQ 14,225) in the treatment of malignant hypertension.
Topics: Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Hypertension, Malignant; Male; Middle Aged; Proline | 1980 |
[Effect of angiotensin converting enzyme inhibitor (SQ 14225) on renin-angiotesin sytem and haemodynamics (author's transl)].
Topics: Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Hemodynamics; Humans; Hypertension; Proline; Renin | 1980 |
Comparative study of an angiotensin-II analog and a converting enzyme inhibitor.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Peptidyl-Dipeptidase A; Proline; Renin; Saralasin | 1980 |
Inhibitors of angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Blood Pressure; Bradykinin; Captopril; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Protease Inhibitors; Rabbits; Rats; Snake Venoms; Structure-Activity Relationship | 1980 |
Effects of angiotensin I converting enzyme inhibitor (SQ 14225) on control of aldosterone.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Female; Potassium; Proline; Rabbits; Renin | 1980 |
Captopril: an oral angiotension converting enzyme inhibitor active in man.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Heart Failure; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Proline; Renal Dialysis | 1980 |
The effect of captopril on blood pressure and angiotensins I, II and III in sodium-depleted dogs: problems associated with the measurement of angiotensin II after inhibition of converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dogs; Male; Proline; Radioimmunoassay; Sodium | 1980 |
Effect of inhibition of converting enzyme on inactive renin in the circulation of salt-replete and salt-deplete normal subjects.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Kidney; Proline; Renin; Sodium Chloride | 1980 |
Role of extrarenal and intrarenal converting enzyme inhibition in renal vasodilator response to intravenous captopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Captopril; Dogs; Female; Femoral Artery; Kidney; Male; Proline; Renal Artery; Vascular Resistance; Vasoconstriction | 1980 |
[A new point of attack for the treatment of hypertension; captopril, an orally active inhibitor of the enzymatic conversion of angiotensin I into angiotensin II].
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Hemodynamics; Humans; Hypertension; Proline; Renin | 1980 |
des-Asp-angiotensin I: its identification in rat blood and confirmation as a substrate for converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Captopril; Dose-Response Relationship, Drug; Hormones; Infusions, Parenteral; Male; Peptidyl-Dipeptidase A; Rats | 1981 |
Responses of blood pressure and angiotensin-converting enzyme activity to acute captopril administration in normotensive and hypertensive rats.
Topics: Angiotensin I; Animals; Blood Pressure; Blood Specimen Collection; Captopril; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Hypertension; Male; Peptidyl-Dipeptidase A; Proline; Rats; Renin | 1981 |
Effect of captopril on the blood pressure response to angiotensin I in turkeys.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Epinephrine; Male; Proline; Time Factors; Turkeys | 1981 |
Effect of angiotensin converting enzyme inhibition with SQ 14 225 on blood pressure in sheep.
Topics: Adrenocorticotropic Hormone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Heart Rate; Proline; Renin; Sheep; Sodium; Water Deprivation | 1981 |
Effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro and its ethyl ester (MK-421) on angiotensin converting enzyme in vitro and angiotensin I pressor responses in vivo.
Topics: Administration, Oral; Anesthesia; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Dipeptides; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Enalapril; Enalaprilat; Esterification; Female; Guinea Pigs; In Vitro Techniques; Male; Rats | 1981 |
Effects of continuous angiotensin I-converting enzyme blockade on blood pressure, sympathetic activity and renin-angiotensin system in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Disease Susceptibility; Hypertension; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Renin; Sympathetic Nervous System | 1981 |
Relationship between inhibition of pressor response to angiotensin I and blood concentration of captopril following a single oral administration to dogs.
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Dogs; Male; Proline; Time Factors | 1981 |
Plasma-converting enzyme activity does not reflect effectiveness of oral treatment with captopril.
Topics: Angiotensin I; Animals; Blood Pressure; Captopril; Hypertension; Male; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains | 1981 |
Vasoactive peptides and hypertension: role of angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Humans; Hypertension; Hypertension, Renovascular; Peptidyl-Dipeptidase A; Renin | 1981 |
Inhibition of the renin-angiotensin system. A new approach to the therapy of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Antihypertensive Agents; Captopril; Enzyme Activation; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin | 1981 |
Inhibition of central angiotensin I conversion by oral captopril.
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Blood-Brain Barrier; Captopril; Injections, Intraventricular; Male; Proline; Rats | 1981 |
Angiotensin converting enzyme inhibition in tissues from spontaneously hypertensive rats after treatment with captopril or MK-421.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dipeptides; Dose-Response Relationship, Drug; Enalapril; Hypertension; Male; Proline; Rats; Time Factors | 1982 |
Converting enzyme inhibition and modulation of plasma renin activity with captopril in anesthetized rats.
Topics: Acetylcholine; Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Isoproterenol; Male; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Renin | 1981 |
[Inhibition of angioten converting enzyme by phosphryl derivatives in rats (author's transl)].
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Male; Proline; Rats; Rats, Inbred Strains; Time Factors | 1981 |
Dissociation between in vivo and in vitro measurements of converting enzyme activity after chronic oral treatment with captopril in rats.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Captopril; Hypertension; Male; Proline; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1982 |
Comparison in normal volunteers of three converting enzyme inhibitors: RHC 3659, MK 421 and captopril.
Topics: Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cyclopentanes; Dipeptides; Dose-Response Relationship, Drug; Enalapril; Humans; Proline | 1982 |
Angiotensin I converting enzyme of rat intestinal and vascular surface membrane.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Bradykinin; Captopril; Intestines; Male; Microscopy, Electron; Peptidyl-Dipeptidase A; Rats; Tissue Distribution | 1982 |
Release of beta-lipotropin- and beta-endorphin-like material induced by angiotensin in the conscious rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; beta-Endorphin; beta-Lipotropin; Captopril; Dexamethasone; Drug Interactions; Endorphins; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Saralasin; Species Specificity | 1982 |
Reversal by acetylsalicylic acid of the captopril-induced inhibition of angiotensin converting enzyme in the hindquarters of guinea-pig.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Biotransformation; Blood Pressure; Captopril; Colon; Diet; Female; Guinea Pigs; Male; Proline | 1982 |
[Changes in angiotensinogen and des-angiotensin I-angiotensinogen in man and rat upon inhibition of converting enzyme].
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Captopril; Humans; Hypertension; Male; Methods; Peptide Fragments; Proline; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin | 1982 |
Comparison of angiotensin converting enzyme inhibitors captopril and MK421-diacid in guinea pig atria.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dipeptides; Enalapril; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Proline | 1982 |
Angiotensin does contribute to drinking induced by caval ligation in rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Drinking Behavior; Male; Proline; Rats; Renin; Thirst; Vena Cava, Inferior | 1982 |
The renin-angiotensin system in the absence of antidiuretic hormone.
Topics: Adrenalectomy; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Captopril; Castration; Diabetes Insipidus; Female; Hypophysectomy; Male; Rats; Rats, Brattleboro; Rats, Mutant Strains; Renin; Sex Factors; Vasopressins; Water-Electrolyte Balance | 1982 |
Pharmacological properties of the converting enzyme inhibitor, enalapril maleate (MK-421).
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diet, Sodium-Restricted; Dipeptides; Dogs; Dose-Response Relationship, Drug; Enalapril; Rats; Rats, Inbred Strains | 1983 |
Attenuation of pressor responses to intracerebroventricular angiotensin I by angiotensin converting enzyme inhibitors and their effects on systemic blood pressure in conscious rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Brain; Captopril; Cerebral Ventricles; Dipeptides; Enalapril; Hypertension; Male; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains | 1983 |
Central angiotensin converting enzyme blockade and thirst.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Carbachol; Drinking Behavior; Male; Rats; Rats, Inbred Strains; Thirst | 1983 |
Coronary vascular actions of the converting enzyme inhibitor, enalapril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Captopril; Cats; Coronary Vessels; Dipeptides; Dose-Response Relationship, Drug; Enalapril; In Vitro Techniques; Kinetics; Vasoconstriction | 1984 |
Influence of converting-enzyme inhibition on rat des-angiotensin I-angiotensinogen.
Topics: Adrenal Glands; Adrenalectomy; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Captopril; Diet, Sodium-Restricted; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sodium | 1984 |
Angiotensin-converting enzyme inhibitory and antihypertensive activities of pivalopril (RHC 3659-(S)).
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Cyclopentanes; Dogs; Dose-Response Relationship, Drug; Hypertension; Kinetics; Male; Rats; Rats, Inbred Strains; Sodium | 1984 |
CI-906 and CI-907: new orally active nonsulfhydryl angiotensin-converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Blood Vessels; Captopril; Dipeptides; Dogs; Enalapril; Guinea Pigs; Heart Rate; Hypertension, Renovascular; In Vitro Techniques; Indoles; Isoquinolines; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Quinapril; Rabbits; Rats; Tetrahydroisoquinolines | 1984 |
Role of angiotensin I and glucagon in canine endotoxin shock: effect of converting enzyme inhibitor and prior immunization.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Glucose; Blood Pressure; Captopril; Cardiac Output; Dogs; Endotoxins; Escherichia coli; Female; Glucagon; Hemodynamics; Male; Proline; Renin; Renin-Angiotensin System; Shock, Septic; Vascular Resistance | 1984 |
Correlation between lung and plasma angiotensin converting enzyme and the hypotensive effect of captopril in conscious rabbits.
Topics: Angiotensin I; Animals; Blood Pressure; Captopril; Cardiac Output; Lung; Male; Peptidyl-Dipeptidase A; Proline; Rabbits; Serotonin; Time Factors | 1984 |
Angiotensin stimulates beta-endorphin release from anterior pituitary gland cell cultures of rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; beta-Endorphin; Captopril; Cells, Cultured; Drug Interactions; Endorphins; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Renin | 1984 |
The feedback regulation of angiotensinogen production by components of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensinogen; Angiotensins; Animals; Captopril; Immunoglobulin G; Liver; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sodium | 1983 |
Angiotensin in the hemodynamic response to chronic nephron obstruction.
Topics: Angiotensin I; Angiotensins; Animals; Blood Pressure; Captopril; Desoxycorticosterone; Glomerular Filtration Rate; Kidney Glomerulus; Male; Microspheres; Nephrons; Rats; Rats, Inbred Strains; Renal Circulation | 1983 |
Angiotensin II in the renal excretory response to behavioral stress in conscious dogs.
Topics: Angiotensin I; Angiotensin II; Animals; Avoidance Learning; Captopril; Dogs; Glomerular Filtration Rate; Humans; Kidney; Male; Renal Circulation; Saralasin; Sodium; Stress, Psychological | 1983 |
The converting enzyme inhibitor captopril stimulates prostacyclin synthesis by isolated rat aorta.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Blood Vessels; Captopril; Epoprostenol; In Vitro Techniques; Proline; Rats | 1983 |
The renin-angiotensin system and drinking in the euryhaline flounder, Platichthys flesus.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Animals; Captopril; Chlorides; Drinking; Fishes; Fresh Water; Osmolar Concentration; Renin-Angiotensin System; Seawater; Sodium | 1983 |
Effect of captopril on the renin-angiotensin system in hypertensive children.
Topics: Adolescent; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Child; Humans; Hypertension; Proline; Renin; Renin-Angiotensin System | 1983 |
Vascular effects and metabolism of angiotensins and their metabolites in the isolated perfused rat kidney.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Kidney; Male; Rats; Rats, Inbred Strains; Renal Circulation; Renin | 1983 |
Stimulation of spontaneous and dopamine-inhibited prolactin release from anterior pituitary reaggregate cell cultures by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Anti-Bacterial Agents; Captopril; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Male; Oligopeptides; Peptides; Pituitary Gland, Anterior; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Characterization of the renin-angiotensin system in the turtle Pseudemys scripta.
Topics: Angiotensin I; Animals; Blood Pressure; Captopril; Female; Hydrogen-Ion Concentration; Kidney; Kinetics; Male; Pressoreceptors; Renin; Renin-Angiotensin System; Turtles | 1984 |
Angiotensin III-induced dipsogenic and pressor responses in rodents.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Captopril; Drinking Behavior; Gerbillinae; Male; Neurosecretory Systems; Rats; Rats, Inbred Strains; Rodentia; Species Specificity | 1984 |
Disappearance of enkephalins in the isolated perfused rat lung.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Assay; Captopril; Colon; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Indomethacin; Lung; Perfusion; Prostaglandins; Rats; Rats, Inbred Strains; Stomach | 1984 |
The vasopressor action of the renin-angiotensin system in the rat snake, Ptyas korros.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Kidney; Male; Norepinephrine; Phentolamine; Renin-Angiotensin System; Reserpine; Saralasin; Snakes; Tissue Extracts | 1984 |
Prostaglandins and the contractile effect of angiotensin I and II in the uterus isolated from ovariectomized rats. Influences of indomethacin and 17-beta estradiol.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Castration; Estradiol; Female; In Vitro Techniques; Indomethacin; Prostaglandins; Rats; Rats, Inbred Strains; Uterine Contraction; Uterus | 1984 |
Chronotropic effects of angiotensin I, angiotensin II, bradykinin and vasopressin in guinea pig atria.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Catecholamines; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Indomethacin; Male; Reserpine; Saralasin; Vasopressins | 1982 |
In vivo conversion of [des-Asp1]-angiotensin I to [des-Asp1]-angiotensin II in conscious sheep.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Captopril; Sheep | 1982 |
Captopril in renovascular hypertension: long-term use in predicting surgical outcome.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension, Renal; Hypertension, Renovascular; Kidney; Male; Middle Aged; Preoperative Care; Prognosis; Proline; Renin | 1982 |
Modification of arterial baroreflexes by captopril in essential hypertension.
Topics: Adult; Angiotensin I; Blood Pressure; Captopril; Heart Rate; Humans; Hypertension; Middle Aged; Nitroglycerin; Phenylephrine; Pressoreceptors; Proline; Reflex | 1982 |
Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Electrolytes; Humans; Hypertension; Long-Term Care; Proline; Renin; Renin-Angiotensin System | 1982 |
Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Angiotensins; Captopril; Cathepsin G; Cathepsins; Chromatography, High Pressure Liquid; Chymosin; Humans; Mast Cells; Neutrophils; Serine Endopeptidases; Skin; Time Factors | 1982 |
Drinking in goats as effect of simultaneous intravenous infusions of angiotensin (I or II) and hypertonic NaCl or mannitol.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Drinking; Female; Goats; Infusions, Parenteral; Male; Mannitol; Saline Solution, Hypertonic; Sodium Chloride | 1981 |
Biological significance of active and inactive renin in man.
Topics: Adult; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Renin; Saralasin | 1980 |
Plasma converting enzyme activity (C.E.A.): an index of plasma levels of captopril?
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Endopeptidases; Male; Proline; Rabbits | 1980 |
Angiotensin-induced release of prostacyclin from perfused organs.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Epoprostenol; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Mesenteric Arteries; Prostaglandins; Rabbits; Saralasin | 1980 |
Interrelation of the renin system and erythropoietin in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Erythropoietin; Female; Hypoxia; Male; Rats; Renin | 1980 |
[An experimental study on the effects of the chronic administration of an angiotensin converting enzyme inhibitor (captopril) on blood pressure and the renin-angiotensin-aldosterone system (author's transl)].
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Captopril; Male; Proline; Rats; Renin | 1980 |
Prostacyclin mediates the potentiated hypotensive effect of bradykinin following captopril treatment.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Epoprostenol; Female; Hemodynamics; Indomethacin; Kidney; Male; Proline; Prostaglandins; Regional Blood Flow | 1980 |
Effective use of captopril (angiotensin I-converting enzyme inhibitor) in severe childhood hypertension.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Child; Humans; Hypertension, Malignant; Proline; Renin | 1980 |
Evidence that the acute hypotensive effect of captopril in dogs is not wholly explained by a reduction of plasma angiotensin II and its direct vasoconstrictor effect.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Male; Proline; Renin; Sodium; Vasoconstriction | 1980 |
Suppression of captopril-induced increase in plasma renin activity by des-Asp1-,Ileu8-angiotensin II in man.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Female; Humans; Hypertension; Isoleucine; Kinetics; Male; Middle Aged; Proline; Renin | 1981 |
Acute effects of captopril on blood pressure and circulating hormone levels in salt-replete and depleted normal subjects and essential hypertensive patients.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Proline; Pulse; Renin; Sodium | 1981 |
Effect of the angiotensin-converting enzyme inhibitor, captopril, on development of renal hypertension in rats.
Topics: Angiotensin I; Animals; Blood Pressure; Body Weight; Bradykinin; Captopril; Drinking; Female; Hypertension, Renal; Organ Size; Proline; Rats | 1981 |
Studies on the mechanism of captopril induced hypotension in rats.
Topics: Angiotensin I; Angiotensins; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Hypotension; Indomethacin; Male; Nephrectomy; Proline; Rats; Saralasin | 1981 |
Captopril attenuates adrenergic vasoconstriction in rat mesenteric arteries by angiotensin-dependent and -independent mechanisms.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Potassium Chloride; Proline; Rats; Saralasin; Vasoconstriction | 1981 |
Angiotensin II's role in mediating angiotensin I- and tetradecapeptide-induced steroidogenesis by rat glomerulosa cells.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Captopril; Female; In Vitro Techniques; Kinetics; Rats | 1981 |
Prostacyclin (PGI2) release accompanying angiotensin conversion in rat mesenteric vasculature.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Epoprostenol; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Prostaglandins; Rats; Saralasin | 1981 |
Pharmacological evaluation in conscious dogs of factors involved in the renal vasodilator effect of captopril.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Female; Indomethacin; Kidney; Male; Proline; Renal Circulation; Saralasin; Vascular Resistance; Vasodilation | 1981 |
Use of captopril in the diagnosis of renal hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension, Renal; Male; Middle Aged; Proline; Renin | 1981 |
[Treatment of refractory arterial hypertension with a converting enzyme inhibiting drug (Captopril)].
Topics: Adolescent; Adult; Angiotensin I; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin | 1981 |
Effect of infused captopril on blood pressure and the renin-angiotensin-aldosterone system in normal dogs subjected to varying sodium balance.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Male; Proline; Renin-Angiotensin System; Vasoconstriction; Water-Electrolyte Balance | 1982 |
Discrimination of renovascular from essential hypertension by converting enzyme inhibition with an orally active compound.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Middle Aged; Proline; Renin | 1982 |
Captopril treatment: inter-dose variations in renin, angiotensins I and II, aldosterone and blood pressure.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin; Renin-Angiotensin System; Time Factors | 1982 |
Further studies on the role of angiotensin in the osmotic control of vasopressin release by the organ-cultured rat hypothalamo-neurohypophyseal system.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Captopril; Drug Synergism; Hypothalamo-Hypophyseal System; Male; Organ Culture Techniques; Osmosis; Rats; Saralasin; Sodium Chloride; Vasopressins | 1982 |
Dependence of renal vasodilator effect of captopril on prevailing plasma renin level in the dog: influence of DOCA-salt treatment.
Topics: Angiotensin I; Animals; Blood Pressure; Captopril; Desoxycorticosterone; Dogs; Female; Kidney; Male; Proline; Regional Blood Flow; Regression Analysis; Renin; Renin-Angiotensin System; Sodium | 1982 |
Telemetric monitoring of cardiovascular parameters in conscious spontaneously hypertensive rats.
Topics: Acetylcholine; Administration, Oral; Analysis of Variance; Angiotensin I; Animals; Blood Pressure; Captopril; Catheterization, Peripheral; Catheters, Indwelling; Femoral Artery; Heart Rate; Hypertension; Injections, Intravenous; Male; Nitroglycerin; Phenylephrine; Plethysmography; Rats; Rats, Inbred SHR; Telemetry | 1993 |
Isolation of a neuropeptide-degrading endopeptidase from the leech Theromyzon tessulatum.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Captopril; Endopeptidases; Enkephalin, Leucine-2-Alanine; Glycopeptides; Hydrolysis; Kinetics; Leeches; Molecular Sequence Data; Molecular Weight; Neuropeptides; Oligopeptides; Protease Inhibitors; Substrate Specificity | 1995 |
Renal pharmacology of GR138950, a novel non-peptide angiotensin AT1 receptor antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzofurans; Captopril; Dogs; Female; Hemodynamics; Kidney; Kidney Function Tests; Male; Renal Agents; Renal Circulation; Urodynamics | 1995 |
Recombinant human hemoglobin (rHb1.1) selectively inhibits vasorelaxation elicited by nitric oxide donors in rabbit isolated aortic rings.
Topics: Angiotensin I; Animals; Aorta; Captopril; Drug Interactions; Female; Hemoglobins; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Phenylephrine; Potassium; Rabbits; Recombinant Proteins; Vasodilation; Vasodilator Agents | 1995 |
Comparison of the transplacental transfer of enalapril, captopril and losartan in sheep.
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Animals; Biological Transport; Biphenyl Compounds; Blood Pressure; Captopril; Enalapril; Female; Fetus; Imidazoles; Injections, Intravenous; Losartan; Placenta; Sheep; Tetrazoles | 1995 |
Analysis of responses to angiotensin peptides in the hindquarters vascular bed of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensins; Animals; Arachidonic Acid; Arginine; Blood Flow Velocity; Captopril; Cats; Dose-Response Relationship, Drug; Female; Hindlimb; Imidazoles; Male; Meclofenamic Acid; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Acid; Phentolamine; Prostaglandin Endoperoxides, Synthetic; Pyridines; Regional Blood Flow; Tetrazoles; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Angiotensin I- and II- and norepinephrine-mediated pressor responses in an ancient holostean fish, the bowfin (Amia calva).
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female; Fishes; Male; Norepinephrine; Phentolamine | 1995 |
Conversion and degradation of [125I] labelled angiotensin I in isolated perfused porcine coronary and carotid arteries.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Carotid Arteries; Coronary Vessels; In Vitro Techniques; Iodine Radioisotopes; Models, Biological; Peptidyl-Dipeptidase A; Perfusion; Swine | 1995 |
Effects of captopril on the human foetal placental circulation: an interaction with bradykinin and angiotensin I.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Indomethacin; Placenta; Placental Function Tests; Pregnancy; Prostaglandins; Regional Blood Flow; Vasoconstriction | 1995 |
Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Captopril; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rabbits; Receptors, Angiotensin | 1995 |
Plasma renin activity in normal healthy volunteers: effect of physiological variables.
Topics: Adolescent; Adult; Aged; Aging; Angiotensin I; Blood Pressure; Captopril; Child; Child, Preschool; Diet, Sodium-Restricted; Female; Humans; Male; Middle Aged; Posture; Radioimmunoassay; Renin; Sex Factors; Sodium, Dietary; Supine Position | 1995 |
Effects of angiotensin II generated by an angiotensin converting enzyme-independent pathway on left ventricular performance in the conscious baboon.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Artifacts; Captopril; Chymases; Consciousness; Diastole; Dose-Response Relationship, Drug; Female; Hemodynamics; Infusions, Intra-Arterial; Male; Mast Cells; Papio; Peptidyl-Dipeptidase A; Serine Endopeptidases; Systole; Tissue Distribution; Ventricular Function, Left | 1995 |
Bradykinin-induced water intake and brain fos-like immunoreactivity in rats.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Brain; Captopril; Drinking; Enalapril; Male; Proto-Oncogene Proteins c-fos; Rats; Renin | 1995 |
Substrate- and inhibitor-specificity of a non-endothelial enzyme which forms [Met5]-enkephalin from [Met5]-enkephalin-Arg6,Phe7 in isolated rabbit ear artery: pharmacological characterization.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Arteries; Bradykinin; Captopril; Disease Models, Animal; Ear, External; Enalapril; Endopeptidases; Endothelium, Vascular; Enkephalin, Methionine; Male; Migraine Disorders; Molecular Sequence Data; Rabbits; Substrate Specificity; Thiorphan | 1995 |
Endocrine changes associated with a rapidly developing sodium appetite in rats.
Topics: Aldosterone; Angiotensin I; Animals; Appetite; Body Weight; Captopril; Diuresis; Dose-Response Relationship, Drug; Drug Interactions; Electrolytes; Furosemide; Male; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium, Dietary | 1994 |
Comparison of pressor responses to angiotensin I, II, and III in pulmonary vascular bed of cats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Captopril; Cats; Female; Imidazoles; Male; Pulmonary Circulation; Tetrazoles | 1994 |
Angiotensin I is converted to angiotensin II by a serine protease in human detrusor smooth muscle.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Enalaprilat; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle, Smooth; Peptidyl-Dipeptidase A; Serine Endopeptidases; Urinary Bladder | 1994 |
Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril.
Topics: Alanine; Amino Acid Sequence; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Bradykinin; Captopril; Cardiomegaly; Dioxoles; Disease Models, Animal; Heart Failure; Hormones; Male; Molecular Sequence Data; Myocardial Infarction; Myocardium; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin | 1994 |
Novel central action of des-Asp-angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Hypothalamus; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Captopril-stimulated renal vein renin measurements in the diagnosis of atherosclerotic renovascular hypertension.
Topics: Adult; Aged; Angiotensin I; Aortography; Arteriosclerosis; Captopril; Female; Humans; Hypertension, Renovascular; Iodine Radioisotopes; Male; Middle Aged; Radioimmunoassay; Renal Artery Obstruction; Renal Veins; Renin | 1994 |
Prolongation by captopril of action potential duration in the normal and hypertrophied rat ventricle: direct action or inhibition of the local angiotensin converting enzyme?
Topics: Action Potentials; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cardiomegaly; Dose-Response Relationship, Drug; Heart; Hypertension; Indoles; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1994 |
Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs.
Topics: Alanine; Anesthesia; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Cyclic GMP; Dogs; Drug Synergism; Female; Kidney; Male; Natriuresis; Neprilysin; Renal Circulation; Vascular Resistance; Vasodilation | 1994 |
Analysis of angiotensins I, II, and III in pulmonary vascular bed of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Blood Vessels; Captopril; Enalaprilat; Imidazoles; In Vitro Techniques; Losartan; Male; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Vasoconstrictor action of angiotensin I-convertase and the synthetic substrate (Pro11,D-Ala12)-angiotensin I.
Topics: Angiotensin I; Animals; Blood Pressure; Callithrix; Captopril; Chymases; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mesenteric Arteries; Potassium Chloride; Serine Endopeptidases; Vasoconstrictor Agents | 1994 |
Vascular renin in the guinea pig. Suppression by the renin inhibitor remikiren.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Captopril; Chromatography, High Pressure Liquid; Guinea Pigs; Hindlimb; Imidazoles; Male; Radioimmunoassay; Renin | 1994 |
Plasma angiotensin I concentration and serum placental leucine aminopeptidase (P-LAP) activities in puerperal hypertension.
Topics: Adult; Angiotensin I; Captopril; Female; Humans; Hypertension; Leucyl Aminopeptidase; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Puerperal Disorders; Renin | 1993 |
[The changes in the levels of angiotensins and angiotensin converting enzyme and effects of captopril in patients with hypoxic pulmonary hypertension].
Topics: Aged; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Peptidyl-Dipeptidase A | 1993 |
Chronic converting enzyme inhibition facilitates baroreceptor resetting to hypertensive levels.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Enalapril; Hypertension; Imidazoles; Losartan; Male; Pressoreceptors; Rats; Rats, Wistar; Reference Values; Regression Analysis; Tetrazoles | 1994 |
Prevention of genetic hypertension by early treatment of spontaneously hypertensive rats with the angiotensin converting enzyme inhibitor captopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR | 1993 |
Marked species-difference in the vascular angiotensin II-forming pathways: humans versus rodents.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Animals; Arteries; Captopril; Female; Humans; In Vitro Techniques; Male; Middle Aged; Oligopeptides; Rabbits; Rats; Rats, Wistar; Serine Endopeptidases; Species Specificity | 1993 |
Nonpeptide angiotensin II receptor antagonists: potential advantages over ACE inhibitors.
Topics: Acrylates; Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cough; Dogs; Enalapril; Female; Glomerular Filtration Rate; Imidazoles; Male; Renal Circulation; Thiophenes | 1993 |
Measurement of angiotensin I converting enzyme inhibition in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Captopril; Cricetinae; Dipeptides; Enalaprilat; Humans; Isoquinolines; Lisinopril; Male; Mesocricetus; Papillary Muscles; Tetrahydroisoquinolines | 1993 |
Deleterious effect of exogenous angiotensin-I on the extent of regional ischaemia and its inhibition by captopril.
Topics: Angiotensin I; Animals; Blood Flow Velocity; Captopril; Coronary Circulation; Dose-Response Relationship, Drug; Male; Myocardial Ischemia; Myocardial Reperfusion; NAD; Organ Culture Techniques; Rabbits; Renin-Angiotensin System | 1993 |
Differential effects of captopril on regional haemodynamic responses to angiotensin I and bradykinin in conscious rats.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Heart Rate; Hemodynamics; Male; Mecamylamine; Rats; Regional Blood Flow; Vascular Resistance; Vasoconstriction | 1993 |
Angiotensinogen is cleaved to angiotensin in isolated rat blood vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Vessels; Captopril; Hindlimb; In Vitro Techniques; Male; Perfusion; Rats; Rats, Sprague-Dawley | 1993 |
Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Dipeptides; Humans; Imidazoles; Losartan; Male; Mice; Mice, Transgenic; Morpholines; Recombinant Proteins; Renin; Renin-Angiotensin System; Tetrazoles | 1993 |
Responses of the bovine mammary artery to angiotensins.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Arteries; Captopril; Cattle; Female; Mammary Glands, Animal | 1993 |
Bradykinin B2 receptor-mediated chronotropic effect of bradykinin in isolated guinea pig atria.
Topics: Adrenergic beta-Agonists; Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Function; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Kallidin; Male; Myocardium; Nitric Oxide; Prostaglandins; Receptor, Bradykinin B2; Receptors, Bradykinin; Sensitivity and Specificity | 1995 |
Involvement of neurohumoral factors in the pressor mechanism of NG-nitro-L-arginine.
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Captopril; Dogs; Female; Hexamethonium; Male; Nitroarginine; Phentolamine; Phenylephrine; Vasoconstrictor Agents | 1995 |
Angiotensin II formation in dog heart is mediated by different pathways in vivo and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Dogs; Hemodynamics; In Vitro Techniques; Male; Myocardium | 1996 |
Renin-angiotensin system in stretch-induced hypertrophy of cultured neonatal rat heart cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Cardiomegaly; Cells, Cultured; Heart; Imidazoles; Losartan; Muscle Proteins; Muscle Spindles; Myocardium; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 1996 |
Effects of angiotensin I and angiotensin II in blood vessels: greater influence of converting enzyme activity in the rabbit basilar artery.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Basilar Artery; Captopril; Carotid Arteries; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 1996 |
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Epoprostenol; Humans; Hypertension; Peptide Fragments | 1996 |
Angiotensin II stimulates sperm motility.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Male; Microscopy, Video; Sperm Motility; Spermatozoa; Stimulation, Chemical | 1996 |
Effect of renin on brain arterioles and cerebral blood flow in rabbits.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Captopril; Cerebrovascular Circulation; Femoral Artery; Injections, Intravenous; Jugular Veins; Laser-Doppler Flowmetry; Male; Rabbits; Renin; Vasodilation | 1996 |
Analysis of responses to angiotensin I-(3-10) in the hindlimb vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Captopril; Cats; Dose-Response Relationship, Drug; Hindlimb; Receptors, Angiotensin; Regional Blood Flow; Vasoconstriction | 1996 |
Vascular angiotensin-converting enzyme expression regulates local angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Gene Expression; Hindlimb; Hypertension, Renal; Male; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1997 |
Distribution of Fos-immunoreactivity in rat brain following a dipsogenic dose of captopril and effects of angiotensin receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain Chemistry; Captopril; Drinking; Enalapril; Hypothalamus; Immunohistochemistry; Male; Naphthyridines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 1997 |
Serum angiotensin converting enzyme activity and response to angiotensin I in horses.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Enalapril; Enalaprilat; Female; Hemodynamics; Horses; Injections, Intravenous; Male; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1989 |
A paradoxical increase in circulating ACE (angiotensin converting enzyme) activity after long-term administration of alacepril (ACE inhibitor).
Topics: Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Reference Values; Renin | 1997 |
Substrate dependence of angiotensin I-converting enzyme inhibition: captopril displays a partial selectivity for inhibition of N-acetyl-seryl-aspartyl-lysyl-proline hydrolysis compared with that of angiotensin I.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Captopril; Chlorides; CHO Cells; Cricetinae; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Oligopeptides; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Substrate Specificity | 1997 |
Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Chromatography, High Pressure Liquid; Coronary Vessels; Dogs; Extracellular Space; Heart Rate; Myocardium; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Renin-Angiotensin System | 1997 |
Angiotensin II type 1 (AT1) receptor-mediated accumulation of angiotensin II in tissues and its intracellular half-life in vivo.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Chromatography, High Pressure Liquid; Diuretics; Endocytosis; Female; Furosemide; Half-Life; Iodine Radioisotopes; Kidney; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine | 1997 |
Role of angiotensin in the dipsogenic effect of bradykinin in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Bradykinin; Brain; Captopril; Cerebral Ventricles; Drinking; Imidazoles; Immunohistochemistry; Losartan; Male; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Thirst | 1997 |
Selective antagonism of the ET(A) receptor reduces neointimal hyperplasia after balloon-induced vascular injury in pigs.
Topics: Angioplasty, Balloon; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Blood Pressure; Captopril; Carotid Artery Injuries; Carotid Artery, Common; Collagen; Endothelin Receptor Antagonists; Endothelin-1; Hyperplasia; Iliac Artery; Male; Muscle, Smooth, Vascular; Pyrrolidines; Receptor, Endothelin A; Swine; Swine, Miniature; Tunica Intima | 1997 |
Angiotensin receptor antagonism and angiotensin converting enzyme inhibition improve diastolic dysfunction and Ca(2+)-ATPase expression in the sarcoplasmic reticulum in hypertensive cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Calcium-Transporting ATPases; Captopril; Cardiomyopathy, Hypertrophic; Diastole; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Mice; Mice, Transgenic; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sarcoplasmic Reticulum; Tetrazoles | 1997 |
Contractile responses of cultured bovine retinal pericytes to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillaries; Captopril; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Nitroprusside; Retinal Vessels; Saralasin; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
[Pro11,D-Ala12]angiotensin I has rapid onset vasoconstrictor activity in the cat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Cats; Female; Hindlimb; Imidazoles; Male; Norepinephrine; Pyridines; Receptors, Angiotensin; Tetrazoles; Time Factors; Vasoconstrictor Agents | 1997 |
Different modulation of steroidogenesis and prostaglandin production in frog ovary in vitro by ACE and ANG II.
Topics: Androgens; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dinoprost; Dinoprostone; Estradiol; Female; Gonadal Steroid Hormones; Kidney; Lisinopril; Lung; Ovary; Peptidyl-Dipeptidase A; Progesterone; Prostaglandins; Rabbits; Rana catesbeiana; Rana esculenta | 1997 |
Angiotensin inhibits neurotransmission of calcitonin gene-related peptide-containing vasodilator nerves in mesenteric artery of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcitonin Gene-Related Peptide; Captopril; Mesenteric Arteries; Methoxamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saralasin; Synaptic Transmission; Thiazepines; Vasodilation; Vasomotor System | 1998 |
Improved analytical procedure for the measurement of captopril in human plasma by gas chromatography--mass spectrometry and its application to pharmacokinetic studies.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity | 1998 |
Cardiac effects of angiotensin I and angiotensin II: dose-response studies in the isolated perfused rat heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Drug; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Perfusion; Rats; Rats, Sprague-Dawley | 1998 |
Pulmonary edema induced by angiotensin I in rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Epinephrine; Losartan; Nitroglycerin; Phentolamine; Pulmonary Edema; Rats; Rats, Wistar; Receptors, Angiotensin; Regression Analysis; Respiration; Vasodilator Agents | 1998 |
Mechanism of beta-adrenergic receptor upregulation induced by ACE inhibition in cultured neonatal rat cardiac myocytes: roles of bradykinin and protein kinase C.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Bradykinin; Captopril; Cells, Cultured; Female; In Vitro Techniques; Isoproterenol; Male; Myocardium; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Bradykinin; Tetrazoles; Up-Regulation | 1998 |
Ixodes scapularis: salivary kininase activity is a metallo dipeptidyl carboxypeptidase.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Assay; Bradykinin; Captopril; Carboxypeptidases; Chromatography, High Pressure Liquid; Cobalt; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Edetic Acid; Female; Guinea Pigs; Hydrogen-Ion Concentration; Ixodes; Manganese; Metalloendopeptidases; Peptide Fragments; Saliva; Salivary Glands; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1998 |
Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Female; Iodine Radioisotopes; Myocardium; Renin; Swine | 1998 |
Functional evidence for alternative ANG II-forming pathways in hamster cardiovascular system.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Aprotinin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Chymases; Cricetinae; Heart Ventricles; Humans; In Vitro Techniques; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Oligopeptides; Serine Endopeptidases; Substrate Specificity; Tetrazoles; Vasoconstriction | 1998 |
Angiotensin II receptor antagonists for heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Captopril; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Receptors, Angiotensin | 1998 |
Chronic sodium balance and blood pressure response to captopril in conscious mice.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Diuretics; Dose-Response Relationship, Drug; Furosemide; Heart Rate; Infusions, Intravenous; Mice; Sodium | 1998 |
Direct vasoconstrictor action of homologous angiotensin II on isolated arterial ring preparations in an elasmobranch fish.
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Vessels; Brachial Artery; Captopril; Celiac Artery; Dogfish; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Mammals; Norepinephrine; Phentolamine; Receptors, Angiotensin; Saralasin; Vasoconstriction | 1998 |
Dual pathway for angiotensin II formation in human internal mammary arteries.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dose-Response Relationship, Drug; Female; Humans; Mammary Arteries; Middle Aged; Oligopeptides; Renin-Angiotensin System; Vasoconstriction | 1998 |
Purification and characterization of angiotensin I-converting enzymes from mesangial cells in culture.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Cattle; Cells, Cultured; Chlorides; Chromatography, Gel; Enalaprilat; Glomerular Mesangium; Hydrogen-Ion Concentration; In Vitro Techniques; Isoenzymes; Molecular Weight; Oligopeptides; Peptidyl-Dipeptidase A; Rats; Substrate Specificity; Temperature | 1998 |
Local renin-angiotensin system and mitogen-activated protein kinase activation in rat aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Captopril; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Male; Nephrectomy; Pepstatins; Protease Inhibitors; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 1999 |
Comparison of irbesartan with captopril effects on cardiac hypertrophy and gene expression in heart failure-prone male SHHF/Mcc-fa(cp) rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Dose-Response Relationship, Drug; Echocardiography; Gene Expression; Heart Failure; Irbesartan; Isoenzymes; Male; Myosin Heavy Chains; Organ Size; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; RNA, Messenger; Systole; Tetrazoles | 1999 |
Analysis of responses to angiotensin I (3-10) and Leu3 angiotensin (3-8) in the pulmonary vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Losartan; Male; Peptide Fragments; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
In vivo assessment of captopril selectivity of angiotensin I-converting enzyme inhibition: differential inhibition of acetyl-ser-asp-lys-pro and angiotensin I hydrolysis.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Hydrolysis; Injections, Intravenous; Kinetics; Male; Oligopeptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Renin; Substrate Specificity; Time Factors | 1999 |
Functional evidence for subfornical organ-intrinsic conversion of angiotensin I to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Drug; Drinking; Electrophysiology; Losartan; Male; Rats; Rats, Wistar; Reaction Time; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Subfornical Organ | 1999 |
Inhibitor analysis of angiotensin I-converting and kinin-degrading activities of bovine lung and testicular angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cattle; Dipeptides; Enalapril; Kinetics; Kinins; Lisinopril; Lung; Male; Peptidyl-Dipeptidase A; Structure-Activity Relationship; Substrate Specificity; Testis | 1999 |
Role of mast cell chymase in angiotensin-induced vascular contraction of hamster cheek pouch microvessels.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chymases; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Male; Mast Cells; Microcirculation; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; p-Methoxy-N-methylphenethylamine; Serine Endopeptidases; Serine Proteinase Inhibitors | 1999 |
Interactions of the systemic and brain renin-angiotensin systems in the control of drinking and the central mediation of pressor responses.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain Chemistry; Captopril; Central Nervous System; Drinking; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 1999 |
Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Newborn; Captopril; Cells, Cultured; Culture Media, Serum-Free; Enzyme Precursors; Fibroblasts; Hypertrophy; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin; Stress, Mechanical | 1999 |
Functional role of local angiotensin-converting enzyme (ACE) in adrenal catecholamine secretion in vivo.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Animals; Captopril; Catecholamines; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Norepinephrine; Peptidyl-Dipeptidase A; Time Factors | 1999 |
The human renin infused rat: use as an in vivo model for the biological evaluation of human renin inhibitors.
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ganglionic Blockers; Humans; In Vitro Techniques; Losartan; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Renin; Time Factors | 1999 |
Nitric oxide modulates captopril-mediated angiotensin-converting enzyme inhibition in porcine iliac arteries.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; In Vitro Techniques; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Peptidyl-Dipeptidase A; S-Nitroso-N-Acetylpenicillamine; Swine; Vasoconstriction; Vasodilation | 1999 |
Changes in angiotensin converting enzyme activity in the renal vascular bed of streptozotocin-induced diabetic rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Drug Interactions; Kidney; Losartan; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renal Artery; Streptozocin; Vasoconstriction | 1999 |
Vasoconstriction by in situ formed angiotensin II: role of ACE and chymase.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Child; Child, Preschool; Chymases; Coronary Vessels; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Pyridines; Serine Endopeptidases; Swine; Tetrazoles; Vasoconstriction | 1999 |
Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Glycopeptides; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Pepstatins; Peptides, Cyclic; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Renin | 2001 |
Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C- and N-domain blockade.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Drug Synergism; Female; Humans; In Vitro Techniques; Isoquinolines; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Receptor, Bradykinin B2; Receptors, Bradykinin; Swine; Tetrahydroisoquinolines; Vasodilation | 2001 |
Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Chymases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Mammary Arteries; Oligopeptides; Peptidyl-Dipeptidase A; Recombinant Proteins; Serine Endopeptidases; Substrate Specificity; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Circulating angiotensin II mediates sodium appetite in adrenalectomized rats.
Topics: Adrenalectomy; Angiotensin I; Angiotensin II; Animals; Appetite Regulation; Behavior, Animal; Blood Pressure; Captopril; Drinking; Drinking Behavior; Drug Administration Schedule; Infusions, Intravenous; Injections, Intraventricular; Male; Potassium; Rats; Rats, Long-Evans; Sodium; Sodium, Dietary | 2001 |
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission | 2001 |
[Activity of the renin-angiotensin-aldosterone system and its impact on the effectiveness of treatment of chronic heart failure in patients with pulmonary tuberculosis].
Topics: Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Heart Failure; Humans; Radioimmunoassay; Ramipril; Renin; Renin-Angiotensin System; Tuberculosis, Pulmonary | 2001 |
The dipsogenic effect of the renin-angiotensin system in elasmobranch fish.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dogfish; Drinking; Female; Fishes; Male; Papaverine; Renin-Angiotensin System; Thirst; Water-Electrolyte Balance | 2001 |
Forebrain renin-angiotensin system has a tonic excitatory influence on renal sympathetic nerve activity.
Topics: Angiotensin I; Animals; Blood Pressure; Captopril; Carotid Arteries; Denervation; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Kidney; Male; Pressoreceptors; Prosencephalon; Rats; Rats, Sprague-Dawley; Reference Values; Renin-Angiotensin System; Sympathetic Nervous System | 2002 |
Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Bradykinin Receptor Antagonists; Captopril; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Male; Mice; Peptide Fragments; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Receptors, Bradykinin; Vasoconstriction | 2002 |
Endothelial function in pigs transgenic for human complement regulating factor.
Topics: Angiotensin I; Animals; Antigens, CD; Bradykinin; Calcimycin; Captopril; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Humans; Male; Membrane Cofactor Protein; Membrane Glycoproteins; Natriuretic Peptide, C-Type; Nitric Oxide; Nitric Oxide Synthase; Swine; Vasodilation | 2002 |
[Peptide-protein complexes of angiotensins in the mechanisms of thirst].
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cattle; Drinking Behavior; Injections, Intraperitoneal; Male; Rats; Rats, Wistar; Serum Albumin, Bovine; Thirst | 2002 |
Renal targeting of captopril selectively enhances the intrarenal over the systemic effects of ACE inhibition in rats.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Immunohistochemistry; Injections, Intravenous; Kidney; Male; Muramidase; Nephrotic Syndrome; Rats; Rats, Wistar; Regional Blood Flow | 2002 |
Inhibition of angiotesin-converting enzyme by quercetin alters the vascular response to brandykinin and angiotensin I.
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Injections, Intravenous; Male; Quercetin; Rats; Rats, Wistar | 2002 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis | 2002 |
Differences between angiotensin-converting enzyme inhibition and angiotensin II-AT1 antagonism on angiotensin-mediated responses in human internal mammary arteries.
Topics: Aged; Aged, 80 and over; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 2003 |
ACE-versus chymase-dependent angiotensin II generation in human coronary arteries: a matter of efficiency?
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chymases; Coronary Vessels; Extracellular Space; Female; Humans; In Vitro Techniques; Isotonic Solutions; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity; Vasoconstriction | 2003 |
Angiotensins in plasma of hypertensive rats and human.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Disease Models, Animal; Enalapril; Humans; Hypertension; Male; Middle Aged; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar | 2003 |
Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Captopril; Disease Models, Animal; Endothelium, Vascular; Female; Hemodynamics; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Vasodilation; Ventricular Fibrillation | 2003 |
Angiotensin I conversion to angiotensin II stimulates cortical collecting duct sodium transport.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Captopril; Culture Techniques; Kidney Tubules, Collecting; Microscopy, Fluorescence; Peptidyl-Dipeptidase A; Rabbits; Sodium | 2003 |
Protein-peptide complexes of angiotensins in the mechanisms of thirst motivation.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Captopril; Drinking Behavior; Drug Combinations; Instinct; Male; Rats; Rats, Wistar; Serum Albumin, Bovine; Thirst; Time Factors | 2003 |
125I-angiotensin I binding in the rat forebrain.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoradiography; Captopril; Choroid Plexus; In Vitro Techniques; Iodine Radioisotopes; Male; Median Eminence; Prosencephalon; Rats; Receptors, Angiotensin; Subfornical Organ | 2003 |
Angiotensin converting anzyme (ACE) activity in porcine ocular tissue: effects of diet and ACE inhibitors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Captopril; Diet, Atherogenic; Enalapril; Female; Peptidyl-Dipeptidase A; Retina; Swine; Swine, Miniature; Time Factors; Uvea | 2003 |
Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats.
Topics: Acetylcholine; Action Potentials; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Anterior Hypothalamic Nucleus; Anti-Arrhythmia Agents; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Imidazoles; Losartan; Male; Muscarinic Antagonists; Neurons; Phenylephrine; Pyridines; Rats; Rats, Wistar; Scopolamine | 2004 |
Captopril blocks the cardiac actions of centrally administered angiotensin I in the trout Oncorhynchus mykiss.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Interactions; Electroencephalography; Endopeptidases; Fourier Analysis; Heart; Heart Rate; Injections, Intraventricular; Oncorhynchus mykiss; Statistics, Nonparametric; Time Factors | 2004 |
Angiotensin-(1-7) antagonist A-779 attenuates the potentiation of bradykinin by captopril in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Captopril; Drug Synergism; Hypertension; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Peptide Fragments; Rats; Rats, Wistar | 2004 |
A genetic variant of ACE increases cell survival: a new paradigm for biology and disease.
Topics: Alu Elements; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Base Sequence; Captopril; Cell Survival; Cells, Cultured; Endothelial Cells; Fluorescent Antibody Technique; Gene Expression Profiling; Humans; Isoenzymes; Molecular Sequence Data; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Sequence Analysis, DNA | 2004 |
Purified angiotensin converting enzyme from Rana esculenta ovary influences ovarian steroidogenesis in vitro.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Female; Hydrogen-Ion Concentration; Lisinopril; Oligopeptides; Ovary; Rana esculenta; Renin; Sodium Chloride; Steroids; Temperature | 2003 |
Differential response of human cardiac fibroblasts to angiotensin I and angiotensin II.
Topics: Angiotensin I; Angiotensin II; Captopril; Cell Line; Collagen; Fibroblasts; Humans; Losartan; Myocardium; Peptidyl-Dipeptidase A | 2004 |
Selective angiotensin-converting enzyme C-domain inhibition is sufficient to prevent angiotensin I-induced vasoconstriction.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Dose-Response Relationship, Drug; Female; Femoral Artery; Humans; Male; Microcirculation; Middle Aged; Oligopeptides; Organ Specificity; Peptidyl-Dipeptidase A; Phosphinic Acids; Protein Structure, Tertiary; Solubility; Structure-Activity Relationship; Sus scrofa; Tetrahydroisoquinolines; Vasoconstriction | 2005 |
A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Glucose; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney Glomerulus; Male; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 2005 |
Mast cell chymase in the ischemic kidney of severe unilateral renovascular hypertension.
Topics: Angiography, Digital Subtraction; Angiotensin I; Angiotensin II; Arteriosclerosis; Captopril; Chymases; Female; Humans; Hyperaldosteronism; Hypertension, Renovascular; Ischemia; Kidney; Mast Cells; Middle Aged; Nephrectomy; Renal Artery; Renal Artery Obstruction; Renal Veins; Renin; Renin-Angiotensin System; Serine Endopeptidases; Smoking | 2005 |
Adrenal angiotensin: origin and site of generation.
Topics: Acrylates; Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Female; Imidazoles; Infusions, Intra-Arterial; Iodine Radioisotopes; Male; Models, Biological; Renin-Angiotensin System; Swine; Thiophenes | 2005 |
Role of elastase-2 as an angiotensin II-forming enzyme in rat carotid artery.
Topics: Amino Acid Chloromethyl Ketones; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Carotid Artery, Common; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Oligopeptides; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases; Serine Proteinase Inhibitors; Vasoconstriction | 2005 |
Effects of long-term angiotensin converting enzyme inhibition on cardiovascular variability in aging rats.
Topics: Aging; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Blood Pressure; Bradycardia; Captopril; Electrocardiography; Heart Rate; Hemodynamics; Male; Rats; Rats, Wistar; Tachycardia | 2006 |
Pressor responses to alligator Angiotensin I and some analogs in the spectacled caiman (Caiman crocodilus).
Topics: Alligators and Crocodiles; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Epinephrine; Losartan; Male; Norepinephrine | 2006 |
Apoptosis and proliferation of mesangial cells isolated from kidneys undergoing compensatory growth following contralateral nephrectomy: role of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Bradykinin; Captopril; Cell Proliferation; Cell Separation; Cells, Cultured; Gene Expression Regulation; Mesangial Cells; Nephrectomy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger | 2007 |
Involvement of angiotensin-(1-7) in the hypothalamic hypotensive effect of captopril in sinoaortic denervated rats.
Topics: Angiotensin I; Animals; Antihypertensive Agents; Aorta, Thoracic; Captopril; Denervation; Drug Synergism; Hypotension; Hypothalamus; Male; Peptide Fragments; Rats; Rats, Wistar | 2008 |
Role of ACE/AT2R complex in the control of mesenteric resistance artery contraction induced by ACE/AT1R complex activation in response to Ang I.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Dose-Response Relationship, Drug; Imidazoles; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Vascular Resistance; Vasoconstrictor Agents | 2008 |
Development of controlled release captopril granules coated with ethylcellulose and methylcellulose by fluid bed dryer.
Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cellulose; Chemistry, Pharmaceutical; Crystallography, X-Ray; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Female; Hypertension; Kinetics; Methylcellulose; Microscopy, Electron, Scanning; Models, Chemical; Povidone; Powder Diffraction; Powders; Rats; Rats, Wistar; Solubility; Technology, Pharmaceutical | 2008 |
Angiotensin-converting enzyme-like activity in crab gills and its putative role in degradation of crustacean hyperglycemic hormone.
Topics: Amino Acids; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Arthropod Proteins; Brachyura; Captopril; Cations, Divalent; Chromatography, High Pressure Liquid; Edetic Acid; Gills; Half-Life; Invertebrate Hormones; Iodine Radioisotopes; Kinetics; Lisinopril; Male; Metals; Nerve Tissue Proteins; Oligopeptides; Peptidyl-Dipeptidase A; Tissue Distribution | 2008 |
Ameliorative effect of Captopril and Valsartan on an animal model of diabetic cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomyopathies; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Female; Isoenzymes; L-Lactate Dehydrogenase; Male; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2008 |
Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis.
Topics: Allosteric Site; Amino Acid Substitution; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Captopril; Catalysis; Catalytic Domain; Chlorides; Enzyme Inhibitors; Humans; Imidazoles; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Peptidyl-Dipeptidase A; Recombinant Proteins; Substrate Specificity | 2008 |
Endogenous angiotensin-(1-7) reduces cardiac ischemia-induced dysfunction in diabetic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Heart; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Nuclear Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger; Signal Transduction | 2009 |
Metabolism of captopril carboxyl ester derivatives for percutaneous absorption.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Aryl Hydrocarbon Hydroxylases; Captopril; Computer Simulation; Cytochrome P-450 CYP2C9; Dose-Response Relationship, Drug; Endoribonucleases; Esterases; Female; Half-Life; Inhibitory Concentration 50; Liver; Mice; Models, Molecular; Prodrugs; Regression Analysis; Skin; Skin Absorption; Swine; Time Factors; Uterus | 2009 |
Isoflavone genistein inhibits the angiotensin-converting enzyme and alters the vascular responses to angiotensin I and bradykinin.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Fluorometry; Genistein; Male; Rats; Rats, Wistar | 2009 |
The effect of angiotensin-converting enzyme inhibition using captopril on energy balance and glucose homeostasis.
Topics: Adipose Tissue; Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Captopril; Dietary Fats; Eating; Energy Metabolism; Glucose; Injections, Intraventricular; Injections, Subcutaneous; Male; Neuropeptide Y; Obesity; Peptidyl-Dipeptidase A; Rats; Rats, Long-Evans; Renin; RNA, Messenger | 2009 |
Ontogenetic role of angiontensin-converting enzyme in rats: thirst and sodium appetite evaluation.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Appetite; Blood Pressure; Body Weight; Captopril; Dehydration; Diuretics, Osmotic; Drinking; Female; Heart Rate; Injections, Intraventricular; Isoproterenol; Kidney; Lactation; Male; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sodium Chloride; Sodium, Dietary; Thirst; Time Factors; Water-Electrolyte Balance | 2010 |
Central angiotensin I increases fetal AVP neuron activity and pressor responses.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Blood Gas Analysis; Blood Pressure; Captopril; Female; Fetus; Heart Rate; Histocytochemistry; Peptidyl-Dipeptidase A; Pregnancy; Proto-Oncogene Proteins c-fos; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sheep; Supraoptic Nucleus | 2010 |
Chronic treatment with quercetin does not inhibit angiotensin-converting enzyme in vivo or in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Chromatography, High Pressure Liquid; In Vitro Techniques; Injections, Intraperitoneal; Male; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar | 2010 |
Drinking and arterial blood pressure responses to ANG II in young and old rats.
Topics: Adaptation, Physiological; Age Factors; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Behavior, Animal; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Heart Rate; Infusions, Intravenous; Male; Minoxidil; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Urodynamics; Vasodilator Agents; Water-Electrolyte Balance | 2010 |
Casein-derived tripeptide Ile-Pro-Pro improves angiotensin-(1-7)- and bradykinin-induced rat mesenteric artery relaxation.
Topics: Angiotensin I; Animals; Blood Pressure; Bradykinin; Captopril; Hypertension; Male; Mesenteric Arteries; Oligopeptides; Peptide Fragments; Rats; Vasodilator Agents | 2011 |
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Brain; Captopril; Cytokines; Heart; Hydralazine; Hypertension; In Vitro Techniques; Insulin; Kidney; Leptin; Male; Myocardial Contraction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Proteinuria; Rats; Rats, Inbred SHR; Ventricular Function, Left | 2011 |
Carboxypeptidase activity common to viridans group streptococci cleaves angiotensin I to angiotensin II: an activity homologous to angiotensin-converting enzyme (ACE).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Base Sequence; Captopril; Carboxypeptidases; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enalapril; Endocarditis, Bacterial; Fibrinogen; Humans; Lisinopril; Molecular Sequence Data; Peptidyl-Dipeptidase A; Sequence Analysis, DNA; Streptococcal Infections; Streptococcus gordonii | 2011 |
Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation.
Topics: Adenocarcinoma; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers, Tumor; Biphenyl Compounds; Captopril; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Gene Expression Regulation, Neoplastic; Irbesartan; Liver Neoplasms, Experimental; Mice; Mice, Inbred CBA; Molecular Targeted Therapy; Neoplasm Proteins; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Tetrazoles; Tumor Burden; Up-Regulation; Vascular Endothelial Growth Factor A | 2011 |
Effects of angiotensin-I and ischemia on functional recovery in isolated hearts.
Topics: Analysis of Variance; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Male; Models, Animal; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Wistar; Recovery of Function; Time Factors | 2011 |
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury | 2012 |
Captopril intake decreases body weight gain via angiotensin-(1-7).
Topics: Adipocytes; Adipose Tissue; Adiposity; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Size; Cells, Cultured; Epididymis; Glycerol; Lipolysis; Male; Peptide Fragments; Primary Cell Culture; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Sterol Esterase; Weight Gain | 2012 |
Involvement of brain ANG II in acute sodium depletion induced salty taste changes.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Appetite; Appetitive Behavior; Body Weight; Captopril; Drug Combinations; Drug Evaluation, Preclinical; Furosemide; Immunohistochemistry; Male; Paraventricular Hypothalamic Nucleus; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Subfornical Organ; Supraoptic Nucleus; Taste | 2012 |
Captopril avoids hypertension, the increase in plasma angiotensin II but increases angiotensin 1-7 and angiotensin II-induced perfusion pressure in isolated kidney in SHR.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Peptide Fragments; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Specific Pathogen-Free Organisms; Vascular Resistance | 2012 |
The renin angiotensin system regulates Kupffer cells in colorectal liver metastases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colorectal Neoplasms; Disease Models, Animal; Gadolinium; Kupffer Cells; Liver Neoplasms; Macrophages; Male; Mice; Mice, Inbred CBA; Peptide Fragments; Renin-Angiotensin System | 2013 |
Effects of neutral endopeptidase (neprilysin) inhibition on the response to other vasoactive peptides in small human resistance arteries: studies with thiorphan and omapatrilat.
Topics: Adrenomedullin; Aged; Angiotensin I; Arteries; Captopril; Female; Humans; Male; Middle Aged; Neprilysin; Protease Inhibitors; Pyridines; Substance P; Thiazepines; Thiorphan; Vasodilation | 2014 |
Angiotensin 1-7 improves insulin sensitivity by increasing skeletal muscle glucose uptake in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Glucose; Insulin Resistance; Male; Muscle, Skeletal; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System | 2014 |
New perspectives in the renin-angiotensin-aldosterone system (RAAS) I: endogenous angiotensin converting enzyme (ACE) inhibition.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Catalytic Domain; Conserved Sequence; Evolution, Molecular; Humans; Hydrogen-Ion Concentration; Hydrolysis; Models, Biological; Molecular Weight; Oligopeptides; Osmolar Concentration; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2014 |
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Captopril; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypertension, Renal; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Random Allocation; Rats, Wistar; Renin; RNA, Messenger | 2015 |
Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Aortic Coarctation; Captopril; Catalase; Clofibrate; Drug Synergism; Heart Ventricles; Hypertension; Lipid Peroxidation; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; PPAR alpha; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Superoxide Dismutase; Vasodilation | 2016 |
Captopril improves postresuscitation hemodynamics protective against pulmonary embolism by activating the ACE2/Ang-(1-7)/Mas axis.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Pressure; Biomarkers; Capillary Permeability; Captopril; Cardiopulmonary Resuscitation; Disease Models, Animal; Enzyme Activation; Female; Heart Arrest; Hemodynamics; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Artery; Pulmonary Edema; Pulmonary Embolism; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Sus scrofa; Thrombolytic Therapy; Time Factors; Vascular Resistance; Ventricular Function, Right; Ventricular Pressure | 2016 |
Bradykinin -induced vasodilatation: Role of age, ACE1-inhibitory peptide, mas- and bradykinin receptors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Humans; Hypertension; Mesenteric Arteries; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, G-Protein-Coupled; Vasodilation | 2016 |
The Interplay between the Renin Angiotensin System and Pacing Postconditioning Induced Cardiac Protection.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Cardiac Pacing, Artificial; Heart; Hemodynamics; Irbesartan; Male; Myocardial Reperfusion Injury; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles | 2016 |
Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats.
Topics: Amlodipine; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Captopril; Coronary Vessels; Losartan; Male; Mineralocorticoid Receptor Antagonists; Models, Animal; Peptide Fragments; Rats, Wistar; Reproducibility of Results; Spironolactone; Time Factors; Vasoconstriction; Vasodilation | 2017 |
ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Captopril; Delayed-Action Preparations; Female; Femur; Humans; Osteolysis; Osteoporosis, Postmenopausal; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Spectrophotometry, Atomic; X-Ray Microtomography | 2017 |
The binding of captopril to angiotensin I-converting enzyme triggers activation of signaling pathways.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; CHO Cells; Cricetulus; Hypertension; Male; MAP Kinase Signaling System; Mesangial Cells; Peptidyl-Dipeptidase A; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Wistar; Signal Transduction | 2018 |
Involvement of angiotensin-(1-7) in the neuroprotection of captopril against focal cerebral ischemia.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Brain Ischemia; Captopril; Male; Neuroprotection; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2018 |
Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthracosis; Captopril; Cell Differentiation; Cell Line; Collagen; Disease Models, Animal; Female; Hedgehog Proteins; Humans; Lung; Male; Middle Aged; Myofibroblasts; Oligopeptides; Peptide Fragments; Pulmonary Fibrosis; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Silicosis | 2019 |
Angiotensin-(1-7) Attenuates Protein O-GlcNAcylation in the Retina by EPAC/Rap1-Dependent Inhibition of O-GlcNAc Transferase.
Topics: Angiotensin I; Animals; Captopril; Cyclic AMP-Dependent Protein Kinases; Diabetic Retinopathy; Mice; N-Acetylglucosaminyltransferases; Peptide Fragments; Renin-Angiotensin System; Retina; Signal Transduction | 2020 |
N-Acetyl-Seryl-Asparyl-Lysyl-Proline regulates lung renin angiotensin system to inhibit epithelial-mesenchymal transition in silicotic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Epithelial-Mesenchymal Transition; Fibrosis; Losartan; Lung; Male; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Silicosis | 2020 |