Page last updated: 2024-08-23

captopril and allopurinol

captopril has been researched along with allopurinol in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19905 (13.89)18.7374
1990's7 (19.44)18.2507
2000's11 (30.56)29.6817
2010's12 (33.33)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Rabkin, SW1
Bagchi, D; Das, DK; Prasad, R1
Cooper, JD; Egan, TM; Minta, JO; Scrimgeour, KG1
Croft, DN; Nunan, TO; O'Doherty, MJ; Pennell, DJ1
Burden, AC; Samanta, A1
Antonovych, TT1
Clapperton, M; Dargie, HJ; Fisher, AC; McMurray, J1
Demiryürek, AT; Kane, KA; Wadsworth, RM; Wainwright, CL1
Manso, CF; Mira, ML; Queiroz, MJ; Silva, MM1
Fujisaki, N; Ikeda, Y; Kuwahara, M; Ohtsuka, Y; Sakemi, T1
Bramble, FJ; Morley, R1
Metodiewa, D; Winterbourn, CC1
Cosic, V; Djordjevic, VB; Jevtovic, T; Kocic, G; Pavlovic, D; Savic, V; Vlahovic, P1
Horio, T; Mizuno, K; Okamoto, H1
Jeppsson, B; Menger, MD; Riaz, AA; Sato, T; Schramm, R; Thorlacius, H; Wang, Y1
Johnson, RJ; Mu, W; Nakagawa, T; Reungjui, S; Roncal, CA; Sánchez-Lozada, LG; Sautin, YY1
Ambrosioni, E; Bacchelli, S; Borghi, C; Esposti, DD; Omboni, S; Reggiardo, G1
Chen, AD; Chen, Q; Kang, YM; Li, YH; Qiu, Y; Wang, JJ; Ye, C; Zheng, F; Zhu, GQ1

Reviews

3 review(s) available for captopril and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-induced nephropathies.
    Pathology annual, 1984, Volume: 19 Pt 2

    Topics: Allopurinol; Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Captopril; Cephalosporins; Cisplatin; Diuretics; Glomerulonephritis; Gold; Humans; Kidney; Kidney Diseases; Kidney Tubular Necrosis, Acute; Lithium; Nephritis, Interstitial; Penicillamine; Penicillins; Rifampin; Semustine; Sulfonamides; Tetracycline; Trimethadione

1984
Effects of the concomitant administration of xanthine oxidase inhibitors with zofenopril or other ACE-inhibitors in post-myocardial infarction patients: a meta-analysis of individual data of four randomized, double-blind, prospective studies.
    BMC cardiovascular disorders, 2018, 06-05, Volume: 18, Issue:1

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Lisinopril; Male; Middle Aged; Myocardial Infarction; Progression-Free Survival; Prospective Studies; Ramipril; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Xanthine Oxidase

2018

Other Studies

33 other study(ies) available for captopril and allopurinol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Cilazapril and captopril accelerate recovery from hypoxia in myocardial cell aggregates in culture.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:3

    Topics: Allopurinol; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Aggregation; Cell Hypoxia; Cells, Cultured; Chick Embryo; Cilazapril; Free Radicals; Heart; Myocardial Contraction; Myocardium; Oxygen; Pyridazines

1992
Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor.
    Biochemical and biophysical research communications, 1989, Jan-16, Volume: 158, Issue:1

    Topics: Allopurinol; Captopril; Cytochrome c Group; Free Radicals; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Superoxide Dismutase; Superoxides; Thiourea

1989
Captopril--a potential free radical scavenger: inhibition of PMN NADPH oxidase.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1988, Volume: 11, Issue:5

    Topics: Captopril; Catalase; Chlorides; Cytochrome c Group; Dithionitrobenzoic Acid; Free Radicals; Humans; Manganese; Manganese Compounds; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines

1988
Fatal Stevens-Johnson syndrome in a patient on captopril and allopurinol.
    Lancet (London, England), 1984, Feb-25, Volume: 1, Issue:8374

    Topics: Aged; Allopurinol; Captopril; Drug Synergism; Humans; Kidney Failure, Chronic; Male; Proline; Stevens-Johnson Syndrome

1984
Fever, myalgia, and arthralgia in a patient on captopril and allopurinol.
    Lancet (London, England), 1984, Mar-24, Volume: 1, Issue:8378

    Topics: Aged; Allopurinol; Captopril; Drug Synergism; Fever; Humans; Joint Diseases; Male; Muscular Diseases; Pain; Proline

1984
Does luminol chemiluminescence detect free radical scavengers?
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:6

    Topics: Antioxidants; Captopril; Free Radical Scavengers; In Vitro Techniques; Luminescent Measurements; Luminol; Sulfhydryl Compounds; Superoxides; Xanthine Oxidase

1995
Characterization of a method for the detection of drugs with free radical scavenging activity using porcine leukocytes.
    Journal of pharmacological and toxicological methods, 1994, Volume: 32, Issue:1

    Topics: Animals; Antioxidants; Azides; Captopril; Catalase; Drug Evaluation, Preclinical; Free Radical Scavengers; Ionomycin; Leukocytes; Luminescent Measurements; Mannitol; Sodium Azide; Superoxide Dismutase; Swine; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines

1994
Angiotensin converting enzyme inhibitors as oxygen free radical scavengers.
    Free radical research communications, 1993, Volume: 19, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Catalase; Chlorides; Deoxyribose; Dimethyl Sulfoxide; Edetic Acid; Enalaprilat; Ferric Compounds; Free Radical Scavengers; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Lisinopril; Luminescent Measurements; Superoxide Dismutase; Xanthine Oxidase

1993
Drug-related low responsiveness to recombinant human erythropoietin therapy in three patients with end-stage renal disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:2

    Topics: Aged; Allopurinol; Anemia; Captopril; Drug Interactions; Drug Resistance; Erythropoietin; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Piperidines; Recombinant Proteins

1997
Cystitis associated with allopurinol.
    British journal of urology, 1997, Volume: 79, Issue:5

    Topics: Aged; Allopurinol; Angiotensin-Converting Enzyme Inhibitors; Antimetabolites; Captopril; Cystitis; Humans; Male; Middle Aged

1997
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.
    Free radical biology & medicine, 1999, Volume: 27, Issue:3-4

    Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Hydrogen Peroxide; Oxygen Consumption; Penicillamine; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxides; Xanthine Oxidase

1999
Does captopril change oxidative stress in puromycin aminonucleoside nephropathy?
    Renal failure, 2000, Volume: 22, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Catalase; Glutathione; Glutathione Peroxidase; Kidney; Male; Oxidative Stress; Puromycin; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Xanthine Oxidase

2000
Inhibitory influences of xanthine oxidase inhibitor and angiotensin I-converting enzyme inhibitor on multinucleated giant cell formation from monocytes by downregulation of adhesion molecules and purinergic receptors.
    The British journal of dermatology, 2004, Volume: 150, Issue:2

    Topics: Allopurinol; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cell Adhesion Molecules; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Giant Cells; Humans; Intercellular Adhesion Molecule-1; Monocytes; Receptors, Purinergic; Xanthine Oxidase

2004
Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:7

    Topics: Allopurinol; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillaries; Captopril; Cell Adhesion; Chemokines; Chemotaxis, Leukocyte; Colon; Constriction; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Gene Expression Regulation; Inflammation; Ischemia; Leukocyte Count; Leukocytes; Losartan; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase

2004
Combination of captopril and allopurinol retards fructose-induced metabolic syndrome.
    American journal of nephrology, 2009, Volume: 30, Issue:5

    Topics: Allopurinol; Angiotensin-Converting Enzyme Inhibitors; Animal Feed; Animals; Antimetabolites; Body Weight; Captopril; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Energy Metabolism; Fructose; Insulin Resistance; Male; Metabolic Syndrome; Rats; Rats, Sprague-Dawley

2009
Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation.
    Neuroscience bulletin, 2020, Volume: 36, Issue:5

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Acetylcysteine; Allopurinol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Capsaicin; Captopril; Ditiocarb; Kidney; Losartan; Male; NADPH Oxidases; Onium Compounds; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Superoxides

2020