Page last updated: 2024-08-23

captopril and aliskiren

captopril has been researched along with aliskiren in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (7.14)	29.6817
2010's	12 (85.71)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dole, WP; Fisher, ND; Hollenberg, NK; Jan Danser, AH; Nussberger, J	1
Bouhuizen, AM; Chai, W; Danser, AH; de Vries, R; Fekkes, D; Garrelds, IM; Krop, M; Ozünal, ZG	1
Bouhuizen, AM; Danser, AH; Garrelds, IM; Leijten, F; Moltzer, E; van Esch, JH; van Veghel, R	1
Celi, A; Cianchetti, S; Del Fiorentino, A; Pedrinelli, R	1
Barkoudah, E; Danser, AH; Fisher, ND; Hollenberg, NK; Moukarbel, GV; Nussberger, J	1
Alexa, IF; Ignat, M; Popovici, E; Popovici, RF; Timpu, D	1
Dursun, N; Kunduz Kindap, E; Ozdogan, K; Taskin, E	1
Lerman, LO	1
Blankestijn, PJ; Hoogduin, H; Leiner, T; Mali, WP; Siddiqi, L; Visser, F	1
Becerril, C; Checa, M; Díaz-Piña, G; García de Alba, C; Montes, E; Ordoñez-Razo, R; Páramo, I; Ruiz, V; Vega, A	1
Andreotti, S; Caminhotto, Rde O; Campaãa, AB; Lima, FB; Sertié, RA	1
Dursun, N; Guven, C; Kaya, ST; Taskin, E; Tuncer, KA	1
Abd El-Latif, HA; El-Yamany, MF; Georgy, GS; Youssef, MM	1

Reviews

1 review(s) available for captopril and aliskiren

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for captopril and aliskiren

Article	Year
Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans. Circulation, 2008, Jun-24, Volume: 117, Issue:25 Topics: Administration, Oral; Adult; Amides; Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Diet; Dose-Response Relationship, Drug; Female; Fumarates; Glomerular Filtration Rate; Humans; Male; Middle Aged; Natriuresis; Predictive Value of Tests; Reference Values; Renal Circulation; Renal Plasma Flow; Renin; Sodium; Sodium, Dietary; Vasodilation	2008
Renal responses to three types of renin-angiotensin system blockers in patients with diabetes mellitus on a high-salt diet: a need for higher doses in diabetic patients? Journal of hypertension, 2011, Volume: 29, Issue:12 Topics: Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fumarates; Humans; Irbesartan; Kidney; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome	2011

Article

Year

Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans.

Circulation, 2008, Jun-24, Volume: 117, Issue:25

Topics: Administration, Oral; Adult; Amides; Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Diet; Dose-Response Relationship, Drug; Female; Fumarates; Glomerular Filtration Rate; Humans; Male; Middle Aged; Natriuresis; Predictive Value of Tests; Reference Values; Renal Circulation; Renal Plasma Flow; Renin; Sodium; Sodium, Dietary; Vasodilation

2008

Renal responses to three types of renin-angiotensin system blockers in patients with diabetes mellitus on a high-salt diet: a need for higher doses in diabetic patients?

Journal of hypertension, 2011, Volume: 29, Issue:12

Topics: Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fumarates; Humans; Irbesartan; Kidney; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome

2011

Other Studies

11 other study(ies) available for captopril and aliskiren

Article	Year
Mast cell degranulation mediates bronchoconstriction via serotonin and not via renin release. European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3 Topics: Amides; Angiotensinogen; Animals; Biphenyl Compounds; Bronchi; Bronchoconstriction; Captopril; Cell Degranulation; Fumarates; In Vitro Techniques; Irbesartan; Male; Mast Cells; Methacholine Chloride; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Tetrazoles	2010
Beneficial cardiac effects of the renin inhibitor aliskiren in spontaneously hypertensive rats. Journal of hypertension, 2010, Volume: 28, Issue:10 Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Fumarates; Heart; Heart Ventricles; Hypertension; Hypertrophy; Irbesartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles	2010
Aliskiren, a renin inhibitor, downregulates TNF-α-induced tissue factor expression in HUVECS. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2010, Volume: 11, Issue:4 Topics: Amides; Captopril; Down-Regulation; Endothelial Cells; Fumarates; Humans; Imidazoles; Renin; Tetrazoles; Thromboplastin; Tumor Necrosis Factor-alpha; Umbilical Veins	2010
In vitro controlled release of antihypertensive drugs intercalated into unmodified SBA-15 and MgO modified SBA-15 matrices. International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2 Topics: Amides; Antihypertensive Agents; Captopril; Delayed-Action Preparations; Drug Carriers; Fumarates; Magnesium Oxide; Nanoparticles; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Surface Properties; X-Ray Diffraction	2012
The restoration of kidney mitochondria function by inhibition of angiotensin-II production in rats with acute adriamycin-induced nephrotoxicity. Renal failure, 2014, Volume: 36, Issue:4 Topics: Adenosine Triphosphate; Amides; Angiotensin II; Animals; Captopril; Creatine Kinase; Doxorubicin; Fumarates; Kidney; Kidney Diseases; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin; Renin-Angiotensin System	2014
Imaging: BOLD assessment--effects of RAAS inhibition in CKD. Nature reviews. Nephrology, 2014, Volume: 10, Issue:5 Topics: Amides; Captopril; Female; Fumarates; Humans; Kidney; Magnetic Resonance Imaging; Male; Oxygen; Renal Insufficiency, Chronic; Renin-Angiotensin System	2014
Inhibition of the renin-angiotensin system affects kidney tissue oxygenation evaluated by magnetic resonance imaging in patients with chronic kidney disease. Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:3 Topics: Adult; Aged; Amides; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Case-Control Studies; Comorbidity; Feasibility Studies; Female; Fumarates; Humans; Hypertension; Kidney; Magnetic Resonance Imaging; Male; Middle Aged; Oxygen; Pilot Projects; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Treatment Outcome	2014
Profibrosing effect of angiotensin converting enzyme inhibitors in human lung fibroblasts. Lung, 2015, Volume: 193, Issue:2 Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Enalapril; Fibroblasts; Fibrosis; Fumarates; Humans; Losartan; Lung; Protein Biosynthesis; Renin; Transcription, Genetic; Transforming Growth Factor beta1	2015
Renin-angiotensin system blockers regulate the metabolism of isolated fat cells in vitro. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2016, Jul-28, Volume: 49, Issue:8 Topics: Adipocytes; Amides; Animals; Antihypertensive Agents; Captopril; Fumarates; Glucose; Glycerol; Lipogenesis; Lipolysis; Losartan; Male; Rats, Wistar; Renin-Angiotensin System	2016
Inhibition of Angiotensin-II Production Increases Susceptibility to Acute Ischemia/Reperfusion Arrhythmia. Medical science monitor : international medical journal of experimental and clinical research, 2016, Nov-27, Volume: 22 Topics: Amides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Captopril; Creatine Kinase, MB Form; Fumarates; Heart; Heart Rate; Male; Myocardial Reperfusion Injury; Oxidative Stress; Rats	2016
Aliskiren and captopril improve cognitive deficits in poorly controlled STZ-induced diabetic rats via amelioration of the hippocampal P-ERK, GSK3β, P-GSK3β pathway. Toxicology and applied pharmacology, 2020, 05-01, Volume: 394 Topics: Amides; Animals; Avoidance Learning; Brain; Captopril; Cholinesterases; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Fumarates; Glycogen Synthase Kinase 3; Hippocampus; Interleukin-1beta; Male; MAP Kinase Signaling System; Maze Learning; Pancreas; Rats; Rats, Sprague-Dawley; Recognition, Psychology	2020