captopril has been researched along with alacepril in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (23.53) | 18.7374 |
| 1990's | 35 (51.47) | 18.2507 |
| 2000's | 10 (14.71) | 29.6817 |
| 2010's | 7 (10.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marumo, F; Nonoguchi, H; Terada, Y; Tomita, K | 1 |
| Hiwada, K; Ochi, T; Sumimoto, T | 1 |
| Hisatome, I; Kinugawa, T; Kitamura, H; Kotake, H; Mashiba, H; Matsumoto, T; Miyakoda, H; Noguchi, N; Ogino, K | 1 |
| Fujishima, M; Ito, Y; Iwase, M; Kobayashi, K; Takata, Y; Tsukashima, A; Ueno, M; Yoshizumi, T | 1 |
| Matsubara, M; Saito, T; Taguma, Y; Yoshinaga, K | 1 |
| Hatanaka, T; Iwai, T; Nagano, M; Nakamura, I; Obara, Y; Takeda, N; Tanamura, A | 1 |
| Hashimoto, T | 1 |
| Iimura, O; Shimamoto, K | 2 |
| Hashimoto, M; Hayashi, K; Hosoki, K; Kadokawa, T; Minato, H; Sawayama, T | 1 |
| Dale, DC; Hammond, WP; Miller, JE; Rosenthal, AS; Starkebaum, G; Zweerink, HJ | 1 |
| Fukuchi, S; Hashimoto, S; Kunii, N; Mizuno, K; Niimura, S; Tani, M; Watari, H; Yabe, R | 1 |
| Fukuya, F; Hosoki, K; Kadokawa, T; Kawahara, S; Minato, H; Takeyama, K | 3 |
| Hashimoto, M; Hosoki, K; Matsumoto, K; Miyazaki, H; Nambu, K; Takeyama, K | 1 |
| Ando, T; Hosoda, S; Ishida, H; Masuda, A; Nakahashi, Y; Shimamoto, K; Tanaka, S; Ura, N; Yamaji, I; Yokoyama, T | 1 |
| Amejima, H; Fujii, T; Hashimoto, M; Matsumoto, K; Miyazaki, H; Yoshida, K | 1 |
| Hori, H; Ito, T; Kadokawa, T; Matsuno, Y; Nakamura, H; Oka, M | 1 |
| Hatano, N; Hosoki, K; Kadokawa, T; Minato, H; Nakatsuji, K; Nose, I; Oka, M; Suzuki, H; Takeyama, K | 1 |
| Hosoki, K; Ikeno, A; Kadokawa, T; Minato, H; Takeyama, K | 1 |
| Fujishima, M; Hayashi, K; Hirakata, H; Motomura, K; Ohchi, N; Omae, T; Onoyama, K; Tomooka, S; Tsuruda, H | 1 |
| Hashimoto, M; Kagemoto, A; Nakao, M; Negoro, T; Sekine, Y | 1 |
| Cheung, B | 1 |
| Hamaguchi, A; Iwao, H; Kim, S; Miura, K; Ohta, K; Yukimura, T | 1 |
| Handa, S; Kitazawa, S; Minami, T; Nagami, K; Suzuki, K; Suzuki, M; Wainai, Y; Yoshikawa, T | 1 |
| Fukuda, M; Itoh, K; Yoshida, S | 1 |
| Gomi, T; Goto, A; Hirawa, N; Ikeda, T; Kawabata, Y; Nagata, T; Ohshima, N; Ono, H; Uehara, Y; Yagi, S | 1 |
| Hamaguchi, A; Iwao, H; Kim, S; Miura, K; Ohta, K; Takaori, K; Yukimura, T | 1 |
| Jougasaki, M; Kato, H; Kikuta, K; Nakao, K; Sumida, H; Tanaka, H; Yasue, H; Yoshimura, M | 1 |
| Itoh, K; Yoshida, S | 1 |
| Goto, A; Hirawa, N; Ikeda, T; Kawabata, Y; Kizuki, K; Ohshima, N; Oka, K; Suzuki, T; Toyo-oka, T; Uehara, Y | 1 |
| Kinugawa, T; Kitamura, H; Kotake, H; Mashiba, H; Miyakoda, H; Saitoh, M | 1 |
| Fujii, S; Miwa, U; Nakabayashi, H; Nishizawa, M; Seta, T; Takeda, R | 1 |
| Ito, M; Izumi, Y; Kanmatsuse, K; Soma, M | 1 |
| Kato, Y; Nara, Y; Sato, T; Yamori, Y | 1 |
| Hayasaki, K; Honda, T; Murohara, T; Sumida, H; Tabuchi, T; Tayama, S; Yasue, H | 1 |
| Chen, S; Ishii, J; Kashiwabara, H; Katayama, S; Kosegawa, I | 1 |
| Hara-Nakamura, N; Hiwada, K; Iwata, T; Kohara, K; Kukita, H; Muneta, S; Ochi, T; Takada, Y | 1 |
| Chen, S; Izumida, T; Katayama, S; Noguchi, Y; Tatebe, J | 1 |
| Fukunaga, Y; Inoue, D; Koshiyama, H; Maeda, S; Sakaguchi, H | 1 |
| Kawai, Y; Matsuki, M; Nishida, S; Sumitomo, S; Yoneda, M | 1 |
| Hiwada, K; Ito, T; Joh, T; Muneta, S; Ochi, T; Sumimoto, T | 1 |
| Mori, A; Noda, Y; Packer, L | 1 |
| Fujitani, B; Honda, Y; Hosoki, K; Masuda, Y; Minato, H | 1 |
| Endo, A; Hamada, T; Hisatome, I; Kato, M; Kato, T; Kinugawa, T; Miyakoda, H; Mori, M; Noguchi, N; Ogino, K; Omodani, H; Osaki, S; Shigemasa, C | 1 |
| Miyazaki, M; Takai, S | 1 |
| Iwamoto, Y; Iwasaki, N; Nanko, H; Wasada, T | 1 |
| Hamada, M; Hiwada, K; Honda, T; Matsumoto, Y; Matsuoka, H; Shigematsu, Y | 1 |
| Katayama, H; Matsuse, T; Ohga, E; Ouchi, Y; Suzuki, M; Teramoto, S | 1 |
| Atarashi, K; Ishiyama, A; Minami, M; Takagi, M | 1 |
| Ishii, T; Matsuse, T; Ohga, E; Ouchi, Y; Suzuki, M; Teramoto, S | 1 |
| Ando, H; Fujimaki, R; Hatano, S; Miyake, F; Nagashima, J; Nobuoka, S; Saito, K; Tokuoka, S | 1 |
| Furuse, Y; Igawa, O; Kato, M; Kinugawa, T; Ogino, K; Osaki, S; Shigemasa, C; Tomikura, Y | 1 |
| Hisatome, I; Igawa, O; Kato, M; Kinugawa, T; Ogino, K; Osaki, S; Shigemasa, C; Shimoyama, M; Tomikura, Y | 1 |
| Ando, H; Furugori, K; Harata, T; Mizutani, S; Murata, Y; Shibata, D | 1 |
| Hirano, K; Iguchi, K; Katagiri, Y; Kiho, T; Kubota, M; Sugiyama, T; Usui, S | 1 |
| Katada, K; Kuroda, M; Manabe, H; Naito, Y; Nakabe, N; Shimozawa, M; Uchiyama, K; Yoshida, N; Yoshikawa, T | 1 |
| Fukushima Kusano, K; Hisamatsu, K; Ishihara, K; Kajiya, M; Miura, A; Miura, D; Miura, R; Morita, H; Nagase, S; Nakamura, K; Ohe, T | 1 |
| Iwasaki, T; Kitamura, Y; Kozaki, Y; Mifune, M; Saito, M; Saito, Y; Tsukamoto, I; Yamaguchi, T | 1 |
| Inoue, T; Kitamura, K; Kiyama, S; Kohda, Y; Nakayama, Y; Naruse, M; Nonoguchi, H; Tajiri, M; Tazoe, N; Tomita, K; Tomita, M | 1 |
| Adachi, Y; Doi, M; Itagaki, T; Katoh, H; Obata, Y; Sato, S; Suzuki, K | 1 |
| Aytemiz, D; Fukayama, T; Fukushima, R; Hamabe, L; Huai-Che, H; Kim, S; Machida, N; Matsumoto, H; Suzuki, S; Tanaka, R; Yamane, Y; Yoshiyuki, R | 1 |
| Aoki, T; Fujii, Y; Orito, K; Shiga, T; Sugimoto, K; Sunahara, H; Takubo, I | 1 |
| Miyagawa, Y; Sakatani, A; Takemura, N | 1 |
| Hitomi, M; Hori, Y; Hosaka, S; Isayama, N; Kanno, N; Mimura, T; Nakamura, K; Yamashita, Y | 1 |
| Goya, S; Hirao, D; Shimada, K; Tanaka, R; Wada, T | 1 |
| Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M | 1 |
8 trial(s) available for captopril and alacepril
| Article | Year |
|---|---|
Anti-proteinuric and anti-coagulatory effects of camostat mesilate in azotemic diabetics.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Blood Coagulation; Captopril; Diabetic Nephropathies; Drug Therapy, Combination; Esters; Female; Gabexate; Guanidines; Humans; Male; Middle Aged; Protease Inhibitors; Proteinuria; Uremia | 1992 |
Responses of plasma concentrations of A type natriuretic peptide and B type natriuretic peptide to alacepril, an angiotensin-converting enzyme inhibitor, in patients with congestive heart failure.
Topics: Administration, Oral; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Captopril; Female; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Pulmonary Wedge Pressure; Time Factors; Vascular Resistance | 1994 |
Effects of angiotensin-converting enzyme inhibitor alacepril in patients with stable effort angina during chronic isosorbide dinitrate treatment.
Topics: Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cross-Over Studies; Double-Blind Method; Drug Tolerance; Exercise Test; Humans; Isosorbide Dinitrate; Male; Middle Aged; Treatment Outcome; Vasodilator Agents | 1996 |
Both a calcium antagonist and ACE inhibitor reverse hypertrophy in hypertension but a calcium antagonist also depresses contractility.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Double-Blind Method; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Contraction; Nicardipine; Ventricular Function, Left | 1997 |
Effects of a new angiotensin-converting enzyme inhibitor, alacepril, on changes in neurohormonal factors and arterial baroreflex sensitivity in patients with congestive heart failure.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Atrial Natriuretic Factor; Baroreflex; Blood Pressure; Body Weight; Captopril; Dose-Response Relationship, Drug; Epinephrine; Female; Heart Failure; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Neuropeptides; Neurotransmitter Agents; Norepinephrine; Renin; Tilt-Table Test; Ventricular Function, Left | 1998 |
Effect of antihypertensive therapy on aortic distensibility in patients with essential hypertension: comparison with trichlormethiazide, nicardipine and alacepril.
Topics: Age Factors; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Echocardiography; Elasticity; Female; Humans; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Nicardipine; Trichlormethiazide | 1999 |
Effects of acute and chronic alacepril treatment on exercise capacity and hemodynamics in patients with heart failure: a preliminary study.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Exercise; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Oxygen Consumption | 2002 |
Evaluation of the effect of an angiotensin-converting enzyme inhibitor, alacepril, on drug-induced renin-angiotensin-aldosterone system activation in normal dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dogs; Female; Renin-Angiotensin System; Time Factors | 2016 |
60 other study(ies) available for captopril and alacepril
| Article | Year |
|---|---|
Renal effects of alacepril in essential hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Electrolytes; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Middle Aged | 1992 |
Effects of a long-term treatment with alacepril on left ventricular hypertrophy and function in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cardiomegaly; Humans; Hypertension; Middle Aged; Prospective Studies; Ventricular Function, Left | 1992 |
Effect of alacepril on blood pressure and neurohumoral factors at rest and during dynamic exercise in patients with essential hypertension.
Topics: Adult; Blood Pressure; Captopril; Exercise; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Rest; Sympathetic Nervous System | 1992 |
Comparison of withdrawing antihypertensive therapy between diuretics and angiotensin converting enzyme inhibitors in essential hypertensives.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Treatment Outcome; Uric Acid | 1992 |
Effects of long-term medication for essential hypertension on cardiac hypertrophy and function.
Topics: Adult; Aged; Blood Pressure; Captopril; Cardiomegaly; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Radiography, Thoracic; Ventricular Function, Left | 1991 |
[Treatment of latent diabetic nephropathy with ACE inhibitor alacepril].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; beta 2-Microglobulin; Captopril; Creatinine; Diabetic Nephropathies; Drug Evaluation; Female; Humans; Kidney; Male; Middle Aged | 1991 |
Significance of kallikrein-kinin and renin-angiotensin systems in the hypotensive mechanism of angiotensin-I converting enzyme inhibitors in essential hypertensives.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Captopril; Diuresis; Heart Rate; Humans; Hypertension; Kallikreins; Kinins; Ramipril; Renin-Angiotensin System | 1989 |
Antihypertensive mechanism of alacepril. Effects of its metabolites on the peripheral sympathetic nervous system.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Electric Stimulation; Enalapril; Male; Nephrectomy; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Nervous System | 1989 |
Suppression of in vitro granulocytopoiesis by captopril and penicillamine.
Topics: Animals; Bone Marrow; Captopril; Catalase; Cells, Cultured; Colony-Forming Units Assay; Dogs; Enalapril; Enalaprilat; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukopenia; Oxygen Consumption; Penicillamine; Sulfhydryl Compounds | 1988 |
Acute effects of the new oral angiotensin converting enzyme inhibitor 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril) in essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1985 |
Antihypertensive activity of alacepril, an orally active angiotensin converting enzyme inhibitor, in renal hypertensive rats and dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hypertension, Renal; Male; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Antihypertensive activity of alacepril in spontaneously hypertensive rats and deoxycorticosterone acetate-salt hypertensive rats and dogs.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Desoxycorticosterone; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Nephrectomy; Rats; Rats, Inbred SHR; Species Specificity | 1985 |
Tissue levels, tissue angiotensin converting enzyme inhibition and antihypertensive effect of the novel antihypertensive agent alacepril in renal hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Hypertension, Renovascular; Kidney; Lung; Male; Rats; Rats, Inbred Strains | 1986 |
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin I; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Dinoprostone; Dogs; Hypertension; Hypertension, Renovascular; Kallikreins; Male; Peptidyl-Dipeptidase A; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Water-Electrolyte Balance | 1986 |
Role of renin-angiotensin and kallikrein-kinin systems on the mechanism of the hypotensive effects of converting enzyme inhibitor, alacepril.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Female; Humans; Hypertension, Renal; Kallikreins; Kinins; Male; Middle Aged; Renin-Angiotensin System | 1987 |
Measurement of circulating kinins, their changes by inhibition of kininase II and their possible blood pressure lowering effect.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hypertension; Kinins; Norepinephrine; Renin | 1987 |
Disposition and metabolism of the novel antihypertensive agent alacepril in rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Bile; Captopril; Feces; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Injections, Intravenous; Intestine, Small; Kidney; Liver; Lung; Male; Rats; Rats, Inbred Strains; Time Factors | 1986 |
General pharmacology of the novel angiotensin converting enzyme inhibitor alacepril. 2nd communication: Effects on central nervous and sensory systems and on the other functions.
Topics: Animals; Anticonvulsants; Antihypertensive Agents; Behavior, Animal; Body Temperature; Capillary Permeability; Captopril; Cats; Central Nervous System; Female; Male; Mice; Neuromuscular Junction; Rabbits; Rats; Reflex; Sensation; Sleep | 1986 |
Effect of the novel orally active angiotensin converting enzyme inhibitor alacepril on cardiovascular system in experimental animals.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiac Output; Cerebrovascular Circulation; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Hypertension, Renovascular; Male; Rats; Rats, Inbred Strains; Renal Circulation; Stroke Volume; Water-Electrolyte Balance | 1986 |
Antihypertensive mechanism of alacepril: effect on norepinephrine-induced vasoconstrictive response in vitro and in vivo.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred Strains; Vasoconstriction | 1986 |
Pharmacokinetics of a new angiotensin I converting enzyme inhibitor (alacepril) after oral dosing in fasting or fed states.
Topics: Administration, Oral; Adult; Biotransformation; Blood Pressure; Captopril; Chromatography, High Pressure Liquid; Drug Evaluation; Fasting; Heart Rate; Humans; Kinetics; Male; Middle Aged | 1985 |
[Syntheses of [prolyl-U-14C]alacepril and its related compounds].
Topics: Antihypertensive Agents; Captopril; Carbon Radioisotopes | 1985 |
Responses of plasma concentrations of A type natriuretic peptide and B type natriuretic to alacepril, an angiotensin-converting enzyme inhibitor, in patients with congestive heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Heart Failure; Humans; Natriuretic Peptide, Brain; Nerve Tissue Proteins | 1995 |
Cardiac hypertrophy-related gene expression in spontaneously hypertensive rats: crucial role of angiotensin AT1 receptor.
Topics: Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Autoradiography; Blotting, Northern; Captopril; Gene Expression; Hypertension; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; RNA, Messenger; Tetrazoles | 1995 |
Effect of the angiotensin-converting enzyme inhibitor alacepril on ventricular function and beta-adrenoceptor number in rabbits with aortic regurgitation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Insufficiency; Captopril; Catecholamines; Female; Hemodynamics; Myocardium; Rabbits; Receptors, Adrenergic, beta; Ventricular Function | 1995 |
The ACE inhibitor alacepril suppresses atherogenesis independent of serum lipids in cholesterol-fed rabbits--critical analysis with new ultrasound technique.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arteriosclerosis; Captopril; Chi-Square Distribution; Cholesterol, Dietary; Echocardiography, Transesophageal; Hypercholesterolemia; Lipids; Male; Rabbits; Regression Analysis | 1994 |
Mechanistic analysis of renal protection by angiotensin converting enzyme inhibitor in Dahl salt-sensitive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood; Blood Pressure; Captopril; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sodium Chloride; Tetrazoles; Urine | 1994 |
Role of angiotensin II in extracellular matrix and transforming growth factor-beta 1 expression in hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Blotting, Northern; Captopril; Collagen; Extracellular Matrix; Gene Expression Regulation; Heart Ventricles; Hypertension; Male; Organ Size; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1994 |
High resolution miniature trans-esophageal echocardiography is useful to evaluate atherosclerosis and the effects of alacepril in hyper-cholesterol rabbits.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Aortic Diseases; Apoproteins; Arteriosclerosis; Captopril; Cholesterol, Dietary; Diet, Atherogenic; Echocardiography, Transesophageal; Hemodynamics; Hypercholesterolemia; Lipoproteins; Male; Miniaturization; Rabbits | 1994 |
Long-term infusion of kallikrein attenuates renal injury in Dahl salt-sensitive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Creatine; Cyclic GMP; Eicosanoids; Hemodynamics; Hypertension; Kallikreins; Kidney; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors | 1994 |
Effects of an angiotensin-converting enzyme inhibitor, alacepril, on cardiovascular and sympathetic nervous responses to mental stress in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cardiovascular System; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Stress, Psychological; Sympathetic Nervous System | 1993 |
[The effect of alacepril on insulin sensitivity in patients with essential hypertension].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Captopril; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged | 1993 |
Effects of long-term treatment with angiotensin-converting enzyme inhibitor on angiotensin II and prostacyclin release from mesenteric arteries in spontaneously hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Epoprostenol; Hypertension; Isoproterenol; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Vasodilation | 1995 |
Effect of antihypertensive treatment with alacepril on insulin resistance in diabetic spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cholesterol, HDL; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypertension; Insulin; Insulin Resistance; Male; Rats; Rats, Inbred SHR; Streptozocin; Triglycerides | 1996 |
Bradykinin may not be involved in improvement of insulin resistance by angiotensin converting enzyme inhibitor.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Child; Diet; Fructose; Glucose; Glucose Intolerance; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Male; Rats; Rats, Wistar; Tetrazoles | 1996 |
Effect of alacepril on 24-hour blood pressure in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Periodicity | 1996 |
A comparison of the hypotensive and hypoglycaemic actions of an angiotensin converting enzyme inhibitor, an AT1a antagonist and troglitazone.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Captopril; Chromans; Diet; Fructose; Hypoglycemic Agents; Insulin Resistance; Male; Monosaccharide Transport Proteins; Rats; Rats, Wistar; Tetrazoles; Thiazoles; Thiazolidinediones; Troglitazone | 1996 |
Hypoglycemia associated with the administration of angiotensin-converting enzyme inhibitor in a patient with diabetes mellitus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Hypoglycemia; Middle Aged | 1997 |
A paradoxical increase in circulating ACE (angiotensin converting enzyme) activity after long-term administration of alacepril (ACE inhibitor).
Topics: Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Reference Values; Renin | 1997 |
Free radical scavenging properties of alacepril metabolites and lisinopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Lisinopril; Nitric Oxide; Superoxides | 1997 |
Alacepril, an angiotensin-converting enzyme inhibitor, prevents cerebral vasospasm in subarachnoid hemorrhage model in rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Basilar Artery; Captopril; Disease Models, Animal; Enalapril; In Vitro Techniques; Ischemic Attack, Transient; Male; Muscle Relaxation; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage | 1997 |
Antiatherosclerotic effect of alacepril, an angiotensin-converting enzyme inhibitor, in monkeys fed a high-cholesterol diet.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Blood Pressure; Blood Proteins; Captopril; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Disease Models, Animal; Female; Follow-Up Studies; Heart Rate; Macaca; Male; Peptidyl-Dipeptidase A | 1999 |
Severe protracted lichenoid eruption and hyperuricemia following administration of alacepril.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Hypertension; Lichenoid Eruptions; Uremia; Uric Acid | 1999 |
Effects of angiotensin-converting enzyme (ACE) inhibitors on oxygen radical production and generation by murine lung alveolar macrophages.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bronchoalveolar Lavage Fluid; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Lisinopril; Luminescent Measurements; Macrophages, Alveolar; Rats; Rats, Inbred F344; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1999 |
Effects of alacepril and amlodipine on the renal injury induced by a high-cholesterol diet in rats.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Captopril; Cholesterol, Dietary; Kidney; Kidney Diseases; Lipids; Male; Proteinuria; Rats; Rats, Sprague-Dawley | 1999 |
Inhibitory effects of angiotensin-converting enzyme (ACE) inhibitors on oxygen radicals produced by bronchoalveolar lavage cells in young and aged guinea pigs.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Bronchoalveolar Lavage Fluid; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Lisinopril; Macrophages, Alveolar; Male; Reactive Oxygen Species | 2000 |
Spatial and temporal analysis of left ventricular filling flow propagation in hypertensive patients before and after regression of myocardial hypertrophy with alacepril therapy.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Captopril; Echocardiography, Doppler, Color; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Regression Analysis; Ventricular Function, Left | 2001 |
Effects of the angiotensin-converting enzyme inhibitor alacepril on exercise capacity and neurohormonal factors in patients with mild-to-moderate heart failure.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cross-Over Studies; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; Neurotransmitter Agents; Patients; Statistics, Nonparametric | 2002 |
Dual renin-angiotensin blockade therapy in patients at high risk of early ovarian hyperstimulation syndrome receiving IVF and elective embryo cryopreservation: a case series.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Chorionic Gonadotropin; Cryopreservation; Drug Therapy, Combination; Embryo Transfer; Embryo, Mammalian; Estradiol; Female; Fertilization in Vitro; Humans; Ovarian Hyperstimulation Syndrome; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles | 2003 |
Sialic acid 9-O-acetylesterase catalyzes the hydrolyzing reaction from alacepril to deacetylalacepril.
Topics: Acetyltransferases; Amino Acid Sequence; Animals; Antihypertensive Agents; Captopril; Chromatography, Liquid; Hydrolysis; Liver; Male; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Rats; Rats, Sprague-Dawley; Sequence Analysis, Protein; Substrate Specificity | 2003 |
The inhibitory effect of alacepril, an angiotensin-converting enzyme inhibitor, on endothelial inflammatory response induced by oxysterol and TNF-alpha.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cell Adhesion; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Inflammation; Intercellular Adhesion Molecule-1; Ketocholesterols; Monocytes; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2004 |
Anti-inflammatory effect of spironolactone on human peripheral blood mononuclear cells.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Male; Mineralocorticoid Receptor Antagonists; Spironolactone; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
Evaluation of the state of active ingredients in pharmaceutical preparations using fourier transform-Raman difference spectra.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antitubercular Agents; Captopril; Chemistry, Pharmaceutical; Crystallization; Delayed-Action Preparations; Fluoroquinolones; Nanoparticles; Pharmaceutical Preparations; Powders; Quality Control; Spectroscopy, Fourier Transform Infrared; Tablets | 2006 |
Long-term plasma levels and dose modulation of alacepril in patients with chronic renal failure.
Topics: Aging; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Body Weight; Captopril; Creatine; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged | 2008 |
[Successful extubation in a patient with alacepril-induced tongue angioedema].
Topics: Anesthesia; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Intubation, Intratracheal; Middle Aged; Neurosurgical Procedures; Perioperative Care; Postoperative Complications; Prone Position; Tongue Diseases | 2010 |
Extreme tetralogy of Fallot in a dog.
Topics: Angiocardiography; Animals; Captopril; Digoxin; Dipyridamole; Dog Diseases; Dogs; Echocardiography; Electrocardiography; Female; Pulmonary Artery; Tetralogy of Fallot; Treatment Outcome | 2013 |
Pharmacodynamics of alacepril in healthy cats.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cats; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Male; Peptidyl-Dipeptidase A | 2017 |
Effects of the angiotensin-converting enzyme inhibitor alacepril in dogs with mitral valve disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dog Diseases; Dogs; Female; Male; Mitral Valve; Mitral Valve Insufficiency; Prospective Studies; Quality of Life; Treatment Outcome | 2018 |
Effects of high-dose alacepril on left atrial pressure and central aortic pressure in awake dogs with mitral valve regurgitation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Pressure; Atrial Function, Left; Atrial Pressure; Blood Pressure; Captopril; Cross-Over Studies; Dog Diseases; Dogs; Female; Male; Mitral Valve Insufficiency | 2019 |
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan | 2019 |