capsaicin has been researched along with thiourea in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.78) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 23 (63.89) | 29.6817 |
| 2010's | 7 (19.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mann, NS | 1 |
| Lai, YL | 1 |
| Raybould, HE; Yoneda, M | 1 |
| Ansay, M; Delaunois, A; Garbarg, M; Gustin, P | 1 |
| Hsu, TH; Kou, YR; Lai, CJ; Lin, YS | 1 |
| Beckers, JF; Bloden, S; Delaunois, A; Gustin, P; Nemmar, A; Sulon, J | 1 |
| Chen, HF; Kou, YR | 1 |
| Beheshti, M; Blumberg, PM; Cho, H; Chun, MW; Hwang, SW; Kim, J; Kim, SY; Lee, J; Marquez, VE; Oh, U; Park, YH; Szabo, T | 1 |
| Kim, KH | 1 |
| Blumberg, PM; Kang, SU; Lee, J; Suh, YG; Szabo, T; Toth, A; Tran, R; Wang, Y; Welter, JD | 1 |
| Choi, JK; Choi, Jy; Choi, Sh; Jeong, YS; Jew, Ss; Kim, HD; Lee, J; Oh, U; Park, Hg; Park, Mk; Park, YH; Suh, Yg | 1 |
| Cho, H; Choi, JY; Choi, SH; Jew, SS; Kim, HD; Kim, MG; Koh, HJ; Lee, J; Lim, KM; Moh, JH; Oh, U; Park, BS; Park, HG; Park, MK; Park, YH; Suh, YG | 1 |
| Blumberg, PM; Choi, HK; Ha, HJ; Kang, M; Kang, SU; Kim, HD; Kim, JM; Kim, YH; Lee, J; Lim, JO; Lundberg, DJ; Oh, U; Park, HG; Park, YH; Pearce, LV; Shin, M; Suh, YG; Toth, A; Tran, R; Wang, Y | 1 |
| Blumberg, PM; Choi, HK; Jin, MK; Kang, SU; Lee, J; Lim, JO; Pearce, LV; Szabo, T; Toth, A; Tran, R; Wang, Y | 1 |
| Cho, H; Choi, JY; Choi, SH; Jew, SS; Kang, SU; Kim, HD; Kyu Choi, J; Lee, J; Oh, U; Park, HG; Park, MK; Park, YH; Su Jeong, Y; Suh, YG | 1 |
| Blumberg, PM; Chen, Z; Kozikowski, AP; Tóth, A | 1 |
| Godlewski, G; Malinowska, B; Schlicker, E | 1 |
| Bölcskei, K; Börzsei, R; Elekes, K; Helyes, Z; Jakab, B; Keszthelyi, D; Németh, J; Petho, G; Pintér, E; Sándor, K; Szabó, A; Szolcsányi, J; Varga, A | 1 |
| Chang, SY; Ho, CY; Kou, YR; Tsai, TL | 1 |
| Blumberg, PM; Ikeda, T; Kang, DW; Lang, KA; Lazar, J; Lee, J; Pavlyukovets, VA; Pearce, LV; Ryu, H | 1 |
| Johansen, ME; Lanza, DL; Moos, PJ; Reilly, CA; Sabnis, AS; Thomas, KC; Yost, GS | 1 |
| Bannon, AW; Deng, H; Gavva, NR; Gore, A; Han, B; Hovland, DN; Juan, T; Klionsky, L; Kuang, R; Le, A; Lehto, SG; Louis, JC; Magal, E; Norman, MH; Surapaneni, S; Tamir, R; Treanor, JJ; Wang, J; Youngblood, B; Zhu, D | 1 |
| Blumberg, PM; Choi, HK; Choi, S; Chung, JU; Kang, B; Kang, DW; Kang, SU; Kim, SY; Lee, J; Lim, JO; Lundberg, DJ; Pavlyukovets, VA; Pearce, LV; Ryu, H; Toth, A; Yoon, HS | 1 |
| Banerjee, B; Mannem, A; Miranda, A; Nordstrom, E; Sengupta, JN; Smith, C | 1 |
| Chancellor, MB; de Groat, WC; Kihara, K; Masuda, H; Matsuoka, Y; Saito, K; Yoshida, S; Yoshimura, N | 1 |
| Berglund, M; Dalence-Guzmán, MF; Skogvall, S; Sterner, O | 1 |
| Kamei, C; Kuyama, S; Ogawa, M; Yokota, E | 1 |
| Banerjee, B; Lehmann, A; Medda, BK; Peles, S; Sengupta, JN; Shaker, R; Zhang, Z | 1 |
| Burbach, LR; Cefalu, JS; Cockayne, DA; Ford, AP; Guillon, MA; Ho, MJ; Hu, DQ; Nunn, PA; Zhu, QM | 1 |
| Pan, Z; Reinach, PS; Wang, Z; Yang, H; Zhang, F | 1 |
| Blumberg, PM; Kang, DW; Kim, MS; Kim, YS; Lang-Kuhs, KA; Lee, J; Lim, KS; Pavlyukovets, VA; Pearce, LV; Tao, AK | 1 |
| Daanen, JF; Kort, ME; Voight, EA | 1 |
| Ichikawa, H; Muramatsu, T; Sahara, Y; Sato, M; Shibukawa, Y; Sobhan, U; Tazaki, M; Tsumura, M | 1 |
| Chancellor, MB; Hinata, N; Honda, M; Inoue, S; Takenaka, A; Yoshimura, N | 1 |
| Chiang, LL; Hsu, CC; Lin, YJ; Lin, YS; Su, CL; Weng, WH | 1 |
| Hai, J; Kawabata, F; Kawabata, Y; Liang, R; Nishimura, S; Tabata, S | 1 |
36 other study(ies) available for capsaicin and thiourea
| Article | Year |
|---|---|
Capsaicin induced acute erosive gastritis: its prevention by antacid, metiamide and cimetidine.
Topics: Acute Disease; Animals; Antacids; Capsaicin; Fatty Acids, Unsaturated; Gastritis; Guanidines; Imidazoles; Male; Metiamide; Rats; Thiourea | 1977 |
Oxygen radicals in capsaicin-induced bronchoconstriction.
Topics: Animals; Bronchi; Capsaicin; Constriction, Pathologic; Guinea Pigs; Male; Oxygen; Thiourea | 1990 |
Capsaicin-sensitive vagal afferent fibers do not contribute to histamine H2 receptor agonist-induced gastric acid secretion in anesthetized rats.
Topics: Anesthesia; Animals; Capsaicin; Dimaprit; Dose-Response Relationship, Drug; Gastric Acid; Injections, Subcutaneous; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Thiourea; Vagus Nerve | 1990 |
Modulation of acetylcholine, capsaicin and substance P effects by histamine H3 receptors in isolated perfused rabbit lungs.
Topics: Acetylcholine; Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Endothelium; Female; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Lung; Male; Nerve Fibers; Piperidines; Pulmonary Edema; Rabbits; Receptors, Histamine H3; Serotonin; Substance P; Thiourea | 1995 |
Involvement of hydroxyl radical in the immediate ventilatory responses to inhaled wood smoke in rats.
Topics: Animals; Capsaicin; Deferoxamine; Free Radical Scavengers; Hydroxyl Radical; Iron; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Siderophores; Smoke; Thiourea; Wood | 1997 |
Modulatory effect of imetit, a histamine H3 receptor agonist, on C-fibers, cholinergic fibers and mast cells in rabbit lungs in vitro.
Topics: Animals; Capsaicin; Carbachol; Cholinergic Fibers; Drug Interactions; Female; Histamine Agonists; Histamine Release; Imidazoles; In Vitro Techniques; Lung; Male; Mast Cells; Rabbits; Radioimmunoassay; Receptors, Histamine H3; Substance P; Thiourea | 1999 |
Vagal and mediator mechanisms underlying the tachypnea caused by pulmonary air embolism in dogs.
Topics: Animals; Capsaicin; Dogs; Embolism, Air; Female; Free Radical Scavengers; Ibuprofen; Male; Nerve Fibers; Pulmonary Embolism; Respiratory Mechanics; Thiourea; Tidal Volume; Time Factors; Vagus Nerve | 2000 |
N-(3-Acyloxy-2-benzylpropyl)-N'-(4-hydroxy-3-methoxybenzyl) thiourea derivatives as potent vanilloid receptor agonists and analgesics.
Topics: Analgesics; Animals; Capsaicin; Male; Mice; Mice, Inbred ICR; Models, Animal; Receptors, Drug; Structure-Activity Relationship; Thiourea | 2001 |
3-D-QSAR analysis of N-(3-acyloxy-2-benzylpropyl)-N'-dihydroxytetrahydrobenzazepine and tetrahydroisoquinoline and N-(3-acyloxy-2-benzylpropyl)-N'-(4-hydroxy-3-methoxybenzyl) thioureas analogues as potent vanilloid receptor ligands.
Topics: Analgesics; Animals; Benzazepines; Capsaicin; Cells, Cultured; Isoquinolines; Ligands; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Rats; Receptors, Drug; Thiourea | 2002 |
High affinity antagonists of the vanilloid receptor.
Topics: Animals; Binding, Competitive; Biological Transport; Calcium; Capsaicin; Cells, Cultured; CHO Cells; Cricetinae; Diterpenes; Hot Temperature; Neurons; Protons; Rats; Receptors, Drug; Sulfonamides; Thiourea | 2002 |
Synthesis of 2-substituted-pyrrolidinethiourea derivatives and their antagonist effect on vanilloid receptor.
Topics: Animals; Animals, Newborn; Calcium; Capsaicin; Crystallography, X-Ray; Indicators and Reagents; Models, Molecular; Molecular Conformation; Neurons, Afferent; Pyrrolidines; Rats; Receptors, Drug; Thiourea | 2003 |
Synthesis of N,N',N"-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor.
Topics: Animals; Animals, Newborn; Calcium; Calcium Isotopes; Capsaicin; Inhibitory Concentration 50; Ion Channels; Neurons; Rats; Receptors, Drug; Structure-Activity Relationship; Thiourea | 2003 |
N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.
Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Ligands; Male; Mice; Mice, Inbred ICR; Rats; Receptors, Drug; Structure-Activity Relationship; Sulfonamides; Thiourea | 2003 |
N-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: analysis of structure-activity relationships for the "C-Region".
Topics: Animals; Biochemistry; Capsaicin; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Rats; Receptors, Drug; Structure-Activity Relationship; Thiourea | 2004 |
N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity.
Topics: Animals; Animals, Newborn; Calcium; Capsaicin; Cells, Cultured; Ganglia, Spinal; Ligands; Molecular Structure; Neurons; Rats; Receptors, Drug; Structure-Activity Relationship; Sulfonamides; Thiourea | 2004 |
Design of a high-affinity competitive antagonist of the vanilloid receptor selective for the calcium entry-linked receptor population.
Topics: Animals; Binding, Competitive; Calcium; Capsaicin; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Drug Design; Receptors, Calcium-Sensing; Receptors, Drug; Thiourea; TRPV Cation Channels | 2004 |
Presynaptic cannabinoid CB(1) receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats.
Topics: Animals; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Blood Pressure; Camphanes; Capsaicin; Decerebrate State; Disease Models, Animal; Electric Stimulation; Germany; Imidazoles; Infusions, Intravenous; Lipopolysaccharides; Male; Norepinephrine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Presynaptic; Rimonabant; Shock, Septic; Solvents; Thiourea; Vagotomy; Vasomotor System; Vasopressins | 2004 |
Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat.
Topics: Animals; Blood Pressure; Body Temperature; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Ion Channels; Male; Neurons; Neuropeptides; Rats; Rats, Wistar; Somatostatin; Substance P; Sulfonamides; Thiourea; Trachea; TRPV Cation Channels | 2005 |
Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
Topics: Action Potentials; Ammonia; Animals; Antioxidants; Blood Pressure; Capsaicin; Deferoxamine; Electrophysiology; Free Radical Scavengers; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Hydroxyl Radical; Inflammation; Laryngeal Muscles; Male; Neurons, Afferent; Pepsin A; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Thiourea | 2006 |
Halogenation of 4-hydroxy-3-methoxybenzyl thiourea TRPV1 agonists showed enhanced antagonism to capsaicin.
Topics: Animals; Bromine; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Halogens; Iodine; Structure-Activity Relationship; Thiourea; TRPV Cation Channels | 2007 |
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells.
Topics: Activating Transcription Factor 3; Arachidonic Acids; Calcium; Capsaicin; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cinnamates; Cyclin D1; Cyclin G2; Cyclins; Diterpenes; Dithiothreitol; Endocannabinoids; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Epithelial Cells; Eukaryotic Initiation Factor-2; Gene Expression; Humans; Lung; Phosphorylation; Polyunsaturated Alkamides; Thapsigargin; Thiourea; Transcription Factor CHOP; Transfection; TRPV Cation Channels | 2007 |
The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation.
Topics: Acrylamides; Animals; Benzothiazoles; Blood-Brain Barrier; Body Temperature Regulation; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cells, Cultured; CHO Cells; Conserved Sequence; Cricetinae; Cricetulus; Dogs; Female; Fever; Humans; Hypothermia; Macaca fascicularis; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Species Specificity; Sulfonamides; Thiourea; TRPV Cation Channels | 2007 |
Alpha-substituted N-(4-tert-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Models, Molecular; Molecular Structure; Rats; Stereoisomerism; Structure-Activity Relationship; Thiourea; TRPV Cation Channels | 2007 |
The role of transient receptor potential vanilloid 1 in mechanical and chemical visceral hyperalgesia following experimental colitis.
Topics: Animals; Capsaicin; Colitis; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Electromyography; Ganglia, Spinal; Gastrointestinal Motility; Hyperalgesia; Male; Neurons; Rats; Rats, Sprague-Dawley; Reflex, Abdominal; Sulfonamides; Thiourea; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels; Visceral Afferents | 2007 |
Reactive oxygen species mediate detrusor overactivity via sensitization of afferent pathway in the bladder of anaesthetized rats.
Topics: Afferent Pathways; Animals; Antioxidants; Capsaicin; Catalase; Cyclooxygenase Inhibitors; Deferoxamine; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Hydrogen Peroxide; Indomethacin; Ketoprofen; Prostaglandins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sensory System Agents; Siderophores; Superoxide Dismutase; Thiourea; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2008 |
SAR studies of capsazepinoid bronchodilators 3: The thiourea part (coupling region) and the 2-(4-chlorophenyl)ethyl moiety (C-region).
Topics: Bronchodilator Agents; Capsaicin; Chlorine Compounds; Humans; Hydrophobic and Hydrophilic Interactions; Lipids; Molecular Structure; Respiration; Structure-Activity Relationship; Thiourea | 2008 |
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Imidazoles; Mice; Mice, Inbred BALB C; Ovalbumin; Piperidines; Pyrrolidines; Receptors, Histamine H3; Rhinitis, Allergic, Perennial; Substance P; Thiourea | 2008 |
Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats.
Topics: Acrylamides; Afferent Pathways; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Disease; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Mechanotransduction, Cellular; Nerve Fibers; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiourea; TRPV Cation Channels; Vagus Nerve | 2009 |
Selective pharmacological blockade of the TRPV1 receptor suppresses sensory reflexes of the rodent bladder.
Topics: Aminopyridines; Animals; Capsaicin; Female; Male; Mice; Mice, Inbred C57BL; Piperazines; Rats; Rats, Sprague-Dawley; Reflex; Sulfonamides; Thiourea; TRPV Cation Channels; Urinary Bladder | 2009 |
TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells.
Topics: Blotting, Western; Calcium; Capsaicin; Cells, Cultured; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fura-2; Humans; Hypertonic Solutions; Interleukin-6; Interleukin-8; Microscopy, Fluorescence; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Stress, Physiological; Sulfonamides; Thiourea; Time Factors; TRPV Cation Channels | 2011 |
Halogenation of 4-hydroxy/amino-3-methoxyphenyl acetamide TRPV1 agonists showed enhanced antagonism to capsaicin.
Topics: Acetamides; Animals; Benzamides; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Halogenation; Rats; Structure-Activity Relationship; Thiourea; TRPV Cation Channels | 2010 |
Synthesis of oxazolo[4,5-c]quinoline TRPV1 antagonists.
Topics: Capsaicin; Crystallography, X-Ray; Heterocyclic Compounds; Magnetic Resonance Spectroscopy; Molecular Structure; Oxazoles; Quinolines; Structure-Activity Relationship; Thiourea; TRPV Cation Channels | 2010 |
TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Cannabinoid Receptor Antagonists; Capsaicin; Cyclic AMP; Diterpenes; Endocannabinoids; Glycerides; Hydrogen-Ion Concentration; Odontoblasts; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Sodium-Calcium Exchanger; Thiourea; TRPV Cation Channels | 2012 |
Inhibitory effect of somatostatin receptor subtype-4 agonist NNC 26-9100 on micturition reflex in rats.
Topics: Afferent Pathways; Aminopyridines; Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin; Somatostatin; Thiourea; Urination | 2012 |
Role of TRPV1 and P2X receptors in the activation of lung vagal C-fiber afferents by inhaled cigarette smoke in rats.
Topics: Animals; Capsaicin; Cholinergic Fibers; Humans; Hydroxyl Radical; Pyridoxal Phosphate; Rats; Reactive Oxygen Species; Receptors, Nicotinic; Receptors, Purinergic P2X; Smoke; Smoking; Thiourea; TRPV Cation Channels | 2013 |
Differences in the effects of TRPV1 antagonists on energy metabolism in mice.
Topics: Animals; Benzothiazoles; Capsaicin; Energy Metabolism; Mice; Mice, Inbred C57BL; Oxygen Consumption; Pyrimidines; Sulfonamides; Thiourea; TRPV Cation Channels | 2018 |