capsaicin has been researched along with substance p in 1289 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 382 (29.64) | 18.7374 |
| 1990's | 572 (44.38) | 18.2507 |
| 2000's | 249 (19.32) | 29.6817 |
| 2010's | 78 (6.05) | 24.3611 |
| 2020's | 8 (0.62) | 2.80 |
| Authors | Studies |
|---|---|
| Gebhart, GF; Virus, RM | 1 |
| Holzer, P; Lembeck, F | 1 |
| Cuello, AC; Iversen, LL; Jessell, TM | 1 |
| Farb, DH; Jessell, TM; Leeman, SE; Yaksh, TL | 1 |
| Jessell, T; Otsuka, M; Theriault, E | 1 |
| Gamse, R; Lembeck, F; Molnar, A | 1 |
| Krause, JE; Sivam, SP | 1 |
| Basbaum, AI; Green, PG; Levine, JD | 1 |
| Bazzani, C; Bertolini, A; Ferrari, W; Guarini, S; Tagliavini, S | 1 |
| Del Bianco, E; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
| Jeftinija, K; Jeftinija, S; Liu, F; Urban, L | 1 |
| Asakura, K; Kataura, A; Kojima, T; Narita, S; Shirasaki, H | 1 |
| Fazekas, A; Györfi, A; Rosivall, L | 1 |
| Cecconi, R; Del Bianco, E; Geppetti, P; Romani, A; Theodorsson, E; Tramontana, M | 1 |
| Huang, Z; Matsubara, T; Moskowitz, MA | 1 |
| Katsumata, K; Kisara, K; Sakurada, S; Sakurada, T; Tan-No, K | 1 |
| Yang, HQ; Zhang, KM; Zhao, ZQ; Zhuang, XX | 1 |
| Breschi, MC; Daffonchio, L; Martinotti, E; Nieri, P; Omini, C | 1 |
| Kuraishi, Y; Minami, M; Onogi, T; Satoh, M | 1 |
| Gebhart, GF; Maves, TJ; Meller, ST | 1 |
| Loomis, CW; Sherman, SE; Vyas, D | 1 |
| Imamura, T; Kambara, T | 1 |
| Zhang, J | 1 |
| Fukushima, T; Ohrui, T; Sasaki, H; Sekizawa, K; Takishima, T; Yamaya, M; Zayasu, K | 1 |
| Håkanson, R; Wallengren, J | 1 |
| Eljamal, M; Miller, IF; Wong, LB; Yeates, DB | 1 |
| Barnes, PJ; Lei, YH; Rogers, DF | 1 |
| Barnes, PJ; Kuo, HP; Rogers, DF; Rohde, JA | 1 |
| Cappugi, P; Lotti, T; Tsampau, D | 1 |
| Marlier, L; Poulat, P; Privat, A; Rajaofetra, N; Sandillon, F | 1 |
| Hylden, JL; Noguchi, K; Ruda, MA | 1 |
| Arts, KS; Fujimoto, JM; Tseng, LF | 1 |
| Agro, A; Blennerhassett, P; Collins, SM; Stanisz, A; Swain, MG | 1 |
| Hiser, WL; Hoffman, JI; Husseini, WK; Nadel, JA; Piedimonte, G | 1 |
| Holmgren, S; Jensen, J | 1 |
| Bachelard, H; Bennett, T; Gardiner, SM; Kemp, PA | 1 |
| Duckles, SP; Li, YJ | 1 |
| Jiang, MM; Surprenant, A | 1 |
| Connelly, CS; Kream, RM; Marchand, JE; Shimonaka, H | 1 |
| Zhu, G | 1 |
| Geisinger, KR; Gilliam, JH; MacLean, DB; Northway, MG | 1 |
| Baluk, P; McDonald, DM; Nadel, JA | 1 |
| Rechtman, MP | 1 |
| Fujii, T; Kiyotoh, S; Maeda, Y; Morimoto, H; Murai, M; Nishikawa, M | 1 |
| Hirose, T; Nishima, S; Umeno, E | 1 |
| Burnstock, G; Cavanagh, JF; Kirkpatrick, KA; Mione, MC | 1 |
| Ahrén, B; Karlsson, S; Sundler, F | 1 |
| Bonici, B; Cuiné, F; Faucher, DC; Garret, C; Laduron, PM; Le Prado, N; Moussaoui, SM | 1 |
| Bordner, J; Bryce, DK; Drozda, SE; Jackson, ER; Longo, KP; Lowe, JA; McLean, S; Morrone, J; Snider, RM; Zorn, SH | 1 |
| Drodge, KH; Scott, TM | 1 |
| Garry, MG; Hargreaves, KM | 1 |
| Aiello, E; Hernandez, C | 1 |
| Connor, HE; Feniuk, W; Stubbs, CM; Waldron, GJ | 1 |
| Manzini, S | 1 |
| Håkanson, R; Wang, ZY | 1 |
| Vincent, MB | 1 |
| Imamura, T; Ishikawa, T; Kambara, T; Kokumai, S; Masuyama, K | 1 |
| Fujii, T; Maeda, Y; Morimoto, H; Murai, M | 1 |
| Aikawa, T; Morikawa, M; Ohrui, T; Sasaki, H; Sekizawa, K; Takishima, T | 1 |
| Bond, A; Boot, JR | 1 |
| Criscuoli, M; Giachetti, A; Guelfi, M; Sardelli, G; Subissi, A | 1 |
| Griesbacher, T; Legat, FJ; Lembeck, F | 1 |
| Harkness, DH; Larson, AA; Skilling, SR | 1 |
| Desmazes, N; Dusser, DJ; Lacroix, H; Lockhart, A | 1 |
| Cotsell, B; Lynn, B; Ye, W | 1 |
| Hosoki, R; Otsuka, M; Yanagisawa, M | 1 |
| Hershman, K; Kream, RM; Kumar, MS; Marchand, JE; Thompson, ML | 1 |
| Andrews, PV; Boyd, RL; Eglezos, A; Helme, RD | 2 |
| Kawasaki, H; Nuki, C; Saito, A; Takasaki, K | 1 |
| Alessandri, M; Campagnolo, V; Fanciullacci, M; Fusco, BM; Geppetti, P; Marabini, S; Nicolodi, M; Sicuteri, F | 1 |
| Kangrga, I; Larew, JS; Randic, M | 1 |
| Amira, S; Morrison, JF; Rayfield, KM | 1 |
| Anderson, J; Baughman, R; Bridenbaugh, R; Kado-Fong, H; Liggitt, D; Malfroy, B; McCabe, J; Mulholland, K | 1 |
| Jin, JG; Nakayama, S | 1 |
| Inoki, R; Ohkubo, T; Shibata, M; Takahashi, H | 2 |
| Marlier, L; Poulat, P; Privat, A; Rajaofetra, N | 1 |
| Del Bianco, E; Geppetti, P; Lippe, IT; Maggi, CA; Santicioli, P; Sicuteri, F | 1 |
| Biggs, DF; Ladenius, RC | 1 |
| Andersson, KE; Andersson, PO; Ekblad, E; Malmgren, A; Sundler, F | 1 |
| Moritoki, H; Takase, H; Tanioka, A | 1 |
| Andersson, RG; Grundemar, L; Grundström, N; Håkanson, R; Johansson, IG | 1 |
| Mantione, CR; Rodriguez, R | 1 |
| Petersson, G; Svensjö, E | 1 |
| Cecconi, R; Geppetti, P; Maggi, CA; Meini, S; Nardi, M; Patacchini, R; Romani, A; Tramontana, M | 1 |
| Burnstock, G; Hudlická, O; Kristek, F; Milner, P; Ralevic, V | 1 |
| Arbab, MA; Delgado-Zygmunt, TJ; Edvinsson, L; Jansen, I; Svendgaard, NA | 1 |
| Karlsson, JA; Kröll, F; Lundberg, JM; Persson, CG | 1 |
| McDonald, DM; Nadel, JA; Umeno, E | 1 |
| Brokaw, JJ; Hillenbrand, CM; McDonald, DM; White, GW | 1 |
| Kangrga, I; Randic, M | 1 |
| Nieber, K; Oehme, P; Schreiber, J; Slapke, J | 1 |
| App, EM; De Sanctis, BI; De Sanctis, GT; Green, FH; King, M; Man, SF; Remmers, JE; Trask, JK | 1 |
| Serova, ON | 1 |
| Kwok, YN; McIntosh, CH | 1 |
| Barnes, PJ; Belvisi, MG; Stretton, CD | 2 |
| Baroldi, P; Maggi, CA; Meli, A; Patacchini, R; Theodorsson, E | 1 |
| Matsuo, S; Nakayama, S; Neya, T | 1 |
| Jin, JG; Nakayama, S; Takaki, M | 2 |
| Criscuoli, M; Guelfi, M; Subissi, A | 1 |
| Ferguson, DR; Hanley, MR; Harrison, SC | 1 |
| Cecconi, R; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
| Matucci-Cerinic, M; Partsch, G | 1 |
| Hayes, L; MacLean, DB; Wheeler, F | 1 |
| Benoliel, JJ; Besson, JM; Bourgoin, S; Carayon, A; Cesselin, F; Hamon, M; Lombard, MC; Mauborgne, A; Pohl, M; Taquet, H | 1 |
| Balu, A; De Sanctis, GT; Fick, G; Green, F; Lopez, A; Prior, M | 1 |
| Geppetti, P; Maggi, CA; Manzini, S; Patacchini, R; Perretti, F; Santicioli, P; Tramontana, M | 1 |
| Couture, R; Jacques, L | 1 |
| Burnstock, G; Hoyle, CH; Ralevic, V | 1 |
| Belmonte, C; Gallar, J; Pozo, MA; Rebollo, I | 1 |
| Livett, BG; Zhou, XF | 1 |
| Bertrand, C; Landry, Y; Theodorsson, E; Tschirhart, E | 1 |
| Brugger, F; Evans, RH; Hawkins, NS | 1 |
| Ennes, H; Eysselein, V; Kodner, A; Koelbel, CB; Mayer, EA; Snape, WJ | 1 |
| McDonald, DM; Nadel, JA; Piedimonte, G | 1 |
| Nakayama, S; Watanabe, Y; Yamasato, T | 1 |
| Helme, RD; Khalil, Z | 2 |
| Nakayama, S; Takaki, M | 1 |
| Almegård, B; Andersson, SE | 1 |
| Geppetti, P; Grassi, J; Maillet, S; Mantellini, P; Renzi, D; Santicioli, P; Surrenti, C; Theodorsson, E | 1 |
| Ashwood, N; Dickenson, A; Dray, A; James, I; Sullivan, AF | 1 |
| Rankin, AJ; Scott, TM | 1 |
| Cao, W; Deng, Y; Dong, X; Lu, Z; Zhang, T | 1 |
| Braun, KP; Goodman, M; Jang, JD; Nishiuchi, Y; Ro, SG; Yaksh, TL | 1 |
| Chen, JA; Han, JD; Liu, Y; Luo, L; Xu, CT; Xu, YX; Zhang, YP | 1 |
| Ohkubo, T; Shibata, M; Takahashi, H | 2 |
| De, AK; Ghosh, JJ | 1 |
| Kopp, UC; Smith, LA | 2 |
| Jin, JG; Lu, YF; Nakayama, S; Takaki, M | 1 |
| Aizawa, H; Ikeda, T; Inoue, H; Miyazaki, N; Shigematsu, N | 1 |
| Boolell, M; Tooke, JE | 1 |
| Amann, R; DelBianco, E; Donnerer, J; Giuliani, S; Lembeck, F; Maggi, CA; Weihe, E | 1 |
| Kontos, HA; Macfarlane, R; Moskowitz, MA; Tasdemiroglu, E; Uemura, Y; Wei, EP | 1 |
| Ingenito, EP; Ingram, RH; Martins, MA; Pliss, LB | 1 |
| Boniotti, A; Graf, PD; Mapp, CE; Nadel, JA | 1 |
| Franco-Cereceda, A | 2 |
| Alafaci, C; Edvinsson, L; Jansen, I; Uddman, R | 1 |
| Brody, MJ; Gebhart, GF; Lewis, SJ; Meller, ST; Ness, TJ | 1 |
| Cagnoni, M; Jantsch, S; Marabini, S; Matucci-Cerinic, M; Partsch, G; Pignone, A | 1 |
| De Sanctis, GT; Green, FH; Remmers, JE | 1 |
| Conlon, JM; McGregor, GP | 1 |
| Amann, R; Donnerer, J | 1 |
| Matsumoto, J; Niida, H; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Ekman, R; Möller, H; Wallengren, J | 1 |
| Aldskogius, H; Kinnman, E | 1 |
| Ando, M; Araki, S; Honda, I; Kohrogi, H; Yamaguchi, T | 1 |
| Dahlqvist, A; Domeij, S; Forsgren, S | 1 |
| Glinska-Ferenz, M; Glinski, W; Pierozynska-Dubowska, M | 1 |
| Fujii, T; Kiyotoh, S; Morimoto, H; Murai, M; Nishikawa, M | 1 |
| Barnes, PJ; Kuo, HP; Rogers, DF; Rohde, JA; Tokuyama, K | 1 |
| Jones, AJ; Keen, P; Ray, NJ | 2 |
| Anggård, A; Lacroix, JS; Lundberg, JM; Stjärne, P | 1 |
| Surprenant, A; Vanner, S | 1 |
| Drazen, JM; Martins, MA; Shore, SA | 2 |
| App, EM; De Sanctis, GT; Green, FH; Hulbert, WC; King, M; Remmers, JE; Rubin, BK | 1 |
| Elde, R; Hill, EL | 1 |
| Alving, K; Hökfelt, T; Lundberg, JM; Matran, R; Panula, P; Sundström, C | 1 |
| Giuliani, S; Maggi, CA; Patacchini, R; Santicioli, P | 1 |
| Evangelista, S; Geppetti, P; Maggi, CA; Mantellini, P; Renzi, D; Santicioli, P; Surrenti, C | 1 |
| Bian, RL; Chen, JQ; Imai, Y; Inoki, R; Ooi, Y; Yonehara, N | 1 |
| Kikuta, A; Nakayama, S; Takaki, M | 1 |
| Myers, AC; Undem, BJ | 2 |
| Benedito, S; Nyborg, NC; Prieto, D | 1 |
| Benedito, S; Nielsen, PJ; Nyborg, NC; Prieto, D | 1 |
| Larson, AA; Sun, XF | 1 |
| Abelli, L; Conte, B; Geppetti, P; Maggi, CA; Parlani, M; Somma, V | 1 |
| Evangelista, S; Mantellini, P; Renzi, D; Surrenti, C | 1 |
| Whittle, BJ | 1 |
| Manzini, S; Perretti, F; Tramontana, M | 1 |
| Casini, A; Evangelista, S; Geppetti, P; Lippe, IT; Maggi, CA; Santicioli, P; Surrenti, C; Urso, C | 1 |
| Karanth, SS; Kuhn, DM; Levene, MM; Polak, JM; Springall, DR | 1 |
| Amann, R; Donnerer, J; Lembeck, F; Skofitsch, G | 1 |
| Amann, R; Donnerer, J; Lembeck, F | 2 |
| Fox, AJ; Morton, IK | 1 |
| Kream, RM; Shimonaka, H | 1 |
| Brodda-Jansen, G; Hedqvist, P; Lundeberg, T; Raud, J; Theodorsson, E | 1 |
| Del Bianco, E; Evangelista, S; Fusco, BM; Geppetti, P; Maggi, CA; Renzi, D; Tramontana, M | 1 |
| Lambracht-Hall, M; Marathias, K; Savala, J; Theoharides, TC | 1 |
| Hammond, DL; Ruda, MA | 2 |
| Elde, R; Hill, EL; Turner, R | 1 |
| Fujita, H; Kawabata, S; Kuraishi, Y; Matsumoto, T; Nakamura, A; Satoh, M | 1 |
| Luk, DE; Nolan, PN; Staszewska-Woolley, J | 2 |
| Ferrell, WR; Lam, FY | 3 |
| Aiello, E; Hernandez, C; Kennedy, J | 1 |
| Amann, R; Giuliani, S; Maggi, CA; Patacchini, R; Santicioli, P; Tramontana, M | 1 |
| Edwall, L; Gazelius, B; Olgart, L | 1 |
| Couture, R; De Champlain, J; Hasséssian, H; Prat, A | 1 |
| Alessandrini, C; D'Antona, D; Fruschelli, C; Fruschelli, M; Guarna, M; Pucci, AM; Volpi, N | 1 |
| Colombo, C; Jeng, AY; Pastor, G; Raychaudhuri, A; Wong, M | 1 |
| Boura, AL; King, RG; Rechtman, MP | 1 |
| Andersson, SE; Le Greves, P | 1 |
| Farley, LG; Finger, TE; Silver, WL | 1 |
| Izumi, H; Karita, K | 2 |
| Burka, JF; Powell, MD; Wright, GM | 1 |
| Amerini, S; Filippi, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Dray, A; Urban, L | 1 |
| Ho, LT; Zochodne, DW | 2 |
| Daniel, EE; Jury, J; Robotham, H | 1 |
| Simmons, MA | 1 |
| Wali, FA | 1 |
| Lindberg, S; Mercke, U | 2 |
| Banno, H; Imaizumi, Y; Watanabe, M | 1 |
| Bissette, G; Decker, MW; Lauder, JM; Mueller, RA; Nemeroff, CB; Towle, AC | 1 |
| Kizawa, Y; Takayanagi, I | 3 |
| Mandahl, A | 1 |
| Jancsó, G; Rózsa, Z; Varró, A | 1 |
| Biggs, DF; Goel, V | 2 |
| Breese, GR; Lauder, J; Mueller, RA; Towle, AC | 1 |
| Eskay, RL; Helke, CJ | 1 |
| MacLean, DB | 1 |
| Fasmer, OB; Hole, K; Hunskaar, S | 1 |
| Dalsgaard, CJ; Lundberg, JM; Martling, CR; Saria, A | 1 |
| Bernard, C; Chayvialle, JA; Chéry-Croze, S; Godinot, F; Jourdan, G | 1 |
| Brodin, E; Hökfelt, T; Hua, XY; Lundberg, JM; Theodorsson-Norheim, E | 1 |
| Fischer, JA; Gamse, R; Lundberg, JM; Petermann, J; Saria, A; Theodorsson-Norheim, E | 1 |
| Dveksler, G; Gimeno, AL; Gimeno, MF | 1 |
| Durkee, KH; Hougland, AE; Hougland, MW | 1 |
| Khalil, Z; Livett, BG; Marley, PD | 2 |
| Gamse, R; Lundberg, JM; Saria, A; Theodorsson-Norheim, E | 2 |
| Chiba, T; Kawano, H; Masuko, S | 1 |
| Kamiya, HO; Kuromizu, K; Masui, H; Nagashima, A; Takano, Y | 1 |
| Bauer, V; Matusák, O | 1 |
| Barthó, L; Holzer, P | 1 |
| Emson, PC; Girgis, S; Kamada, T; Kimura, K; MacIntyre, I; Matsuyama, T; Tohyama, M; Wanaka, A; Yoneda, S | 1 |
| Balentine, JD; Schulte, BA; Spicer, SS; Streit, WJ | 1 |
| Maggi, CA; Meli, A | 1 |
| Duckles, SP | 1 |
| Bloom, SR; Ghatei, MA; Gulbenkian, S; McGregor, GP; Mulderry, PK; Polak, JM; Wharton, J | 1 |
| Dunér-Engström, M; Fredholm, BB; Larsson, O; Lundberg, JM; Saria, A | 1 |
| Kreulen, DL; Peters, S | 2 |
| Go, VL; Micevych, PE; Stroink, A; Yaksh, T | 1 |
| Bell, JA; Jaffe, JH | 1 |
| Blinn, JR; Dobry-Schreur, PJ; Moon, MW; Piercey, MF | 1 |
| Fujiwara, M; Muramatsu, I; Nakanishi, S; Taniguchi, T; Ueda, N | 1 |
| Hua, XY | 1 |
| Henschen, A; Kessler, J; Olson, L; Seiger, A | 1 |
| Esakov, AI; Solov'eva, NA | 1 |
| Bengtsson, B; Khan, AR; Lindberg, S | 1 |
| Campbell, G; Osborne, P | 1 |
| Arwestrom, E; Fasmer, OB; Hunskaar, S; Post, C | 1 |
| Brodin, E; Gamse, R; Hua, XY; Lundberg, JM; Saria, A; Theodorsson-Norheim, E | 1 |
| Jaffe, JH; Sharpe, LG | 2 |
| Möller, H; Wallengren, J | 1 |
| Hua, XY; Lundberg, JM | 1 |
| Demarest, KT; Genovesi, S; Stein, RD; Weaver, LC | 1 |
| Berkenbosch, F; Schipper, J; Tilders, FJ | 1 |
| Burchiel, KJ; Russell, LC | 2 |
| Couture, R; Jacques, L; Kérouac, R | 1 |
| Liu-Chen, LY; Moskowitz, MA; Saito, K | 1 |
| Fujii, N; Oku, R; Otaka, A; Satoh, M; Takagi, H; Yajima, H | 1 |
| King, TR; Nance, DM; Nance, PW | 1 |
| Cornett, AF; Lai, YL | 1 |
| Foreman, JC | 2 |
| Daniel, EE; Kalbfleisch, RE | 1 |
| Helme, RD; McKernan, S | 1 |
| Bernstein, JE | 2 |
| Frilli, S; Geppetti, P; Maggi, CA; Meli, A; Santicioli, P; Spillantini, MG | 1 |
| Abelli, L; Giuliani, S; Maggi, CA; Meli, A; Regoli, D; Santicioli, P | 1 |
| Gordon, T; Scypinski, LA; Sheppard, D; Thompson, JE | 1 |
| Abelli, L; Evangelista, S; Maggi, CA; Meli, A; Somma, V | 1 |
| Conte, B; Fanciullacci, M; Frilli, S; Furio, M; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Santicioli, P | 1 |
| Harti, G; Pierau, FK; Sann, H; Simon, E | 1 |
| Bacciarelli, C; Geppetti, P; Maggi, CA; Manzini, S | 1 |
| Eglezos, A; Helme, RD; Hosking, CS | 1 |
| Fujiwara, M; Muramatsu, I; Nakanishi, S | 1 |
| Crema, A; Manzo, L; Onori, L; Perucca, E; Rizzi, CA; Tonini, M | 1 |
| Abelli, L; Capasso, M; Conte, B; Giuliani, S; Maggi, CA; Meli, A; Parlani, M; Santicioli, P | 1 |
| Beding, B; Ekman, R; Håkanson, R; Heilig, M; Sundler, F; Wahlestedt, C | 1 |
| Dun, NJ; Lundberg, JM; Ma, RC; Saria, A; Theodorsson-Norheim, E | 1 |
| Buckner, CK; Dick, EC; Fishleder, RI; Saban, R | 1 |
| Aronin, N; Clements, RS; Leeman, SE | 1 |
| Inoki, R; Shibutani, T; Yonehara, N | 1 |
| Otsuka, M; Yanagisawa, M | 2 |
| Randić, M; Urbán, L | 2 |
| Chahl, LA; Lynch, AM | 1 |
| Gamse, R; Hua, XY; Lundberg, JM; Martling, CR; Saria, A; Theodorsson-Norheim, E | 1 |
| Papka, RE; Urban, L | 1 |
| Greenspon, JM; Mason, JR; Silver, WL | 1 |
| Hoover, DB | 1 |
| Gamse, R; Loidolt, D; Saria, A; Wolf, G | 1 |
| Amenta, F; Frilli, S; Geppetti, P; Maggi, CA; Meli, A; Santicioli, P; Spillantini, MG; Zecchi-Orlandini, S | 1 |
| Ando, K; Ishida, Y; Iwamoto, T; Kanaya, J; Kitagawa, K; Moritoki, H | 1 |
| de Jong, W; de Wied, D; Lukovic, L | 1 |
| Andrews, PV; Boyd, RL; Dandie, GW; Eglezos, A; Helme, RD | 2 |
| Fujita, S; Fukuda, T; Izumi, K; Koja, T; Ohba, N; Shimizu, T; Sorimachi, M | 1 |
| Cervero, F; Sharkey, KA; Sobrino, JA | 1 |
| Franco-Cereceda, A; Lundberg, JM; Rudehill, A | 1 |
| Knox, C; Seybold, VS; Tuchscherer, MM | 1 |
| Andersson, SE | 1 |
| Sheppard, D; Thompson, JE | 1 |
| Frilli, S; Geppetti, P; Giuliani, S; Grassi, J; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Abelli, L; Amenta, F; Borsini, F; Evangelista, S; Geppetti, P; Maggi, CA; Manzini, S; Santicioli, P; Somma, V; Theodorsson-Norheim, E | 1 |
| Abelli, L; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Renzi, D; Santicioli, P; Somma, V | 1 |
| Go, VL; Yaksh, TL | 1 |
| Asami, T; Hori, T; Kiyohara, T; Nakashima, T; Shibata, M | 1 |
| Fischer, JA; Hökfelt, T; Lundberg, JM; Martling, CR; Saria, A | 1 |
| Bergren, DR | 3 |
| Lynn, B; Shakhanbeh, J | 1 |
| Astolfi, M; Frilli, S; Fusco, B; Geppetti, P; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Maggi, CA; Meli, A; Patacchini, R; Santicioli, P; Theodorsson, E | 1 |
| Hawk, RJ; Millikan, LE | 1 |
| Brodin, E; Linderoth, B | 1 |
| Crimi, N; Mistretta, A | 1 |
| Frilli, S; Geppetti, P; Maggi, CA; Manzini, S; Perretti, F | 1 |
| Alessandri, M; Amenta, F; Ballerini, G; Fanciullacci, M; Geppetti, P; Maggi, CA; Santicioli, P; Theodorsson-Norheim, E | 1 |
| Bossut, D; Frenk, H; Mayer, DJ; Urca, G | 1 |
| Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Frilli, S; Furio, M; Fusco, B; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Santicioli, P; Theodorsson, E | 1 |
| Frilli, S; Geppetti, P; Hunt, SP; Maggi, CA; Meli, A; Nediani, C; Santicioli, P; Spillantini, MG | 1 |
| Zhu, GQ | 1 |
| Astolfi, M; Geppetti, P; Maggi, CA; Meli, A; Parlani, M; Patacchini, R; Pradelles, P; Santicioli, P | 1 |
| Del Bianco, E; Geppetti, P; Giuliani, S; Lippe, IT; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P; Selleri, S | 1 |
| Gilberti, G; Rapuzzi, G; Villa, A | 1 |
| Lundberg, JM; Mejia, JA; Pernow, J; Rudehill, A; von Holst, H | 1 |
| Borson, DB; Graf, PD; Kohrogi, H; Nadel, JA; Sekizawa, K | 1 |
| Maggi, CA; Meli, A; Pradelles, P; Renzi, D; Santicioli, P; Surrenti, C | 1 |
| Gamse, R; Lundberg, JM; Martling, CR; Saria, A; Theodorsson-Norheim, E; Yan, Z | 1 |
| Yaksh, TL | 1 |
| Barnes, PJ; Frossard, N; Rhoden, KJ | 1 |
| Borson, DB; Djokic, TD; Dusser, DJ; Graf, PD; Nadel, JA; Sekizawa, K | 1 |
| Astolfi, GM; Baldi, E; Fusco, B; Geppetti, P; Giuliani, S; Maggi, CA; Parlani, M; Patacchini, R; Santicioli, P; Theodorsson, E | 1 |
| Jacobson, ED; Rozsa, Z | 1 |
| Alm, P; Lundberg, LM | 1 |
| Maggi, CA; Meli, A; Patacchini, R; Renzi, D; Santicioli, P; Surrenti, C | 1 |
| Amann, R; Dray, A; Hankins, MW | 1 |
| Koidl, B; Saria, A; Wolf, G | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Hamon, M; Mauborgne, A; Pohl, M | 1 |
| Fanciullacci, M; Frilli, S; Geppetti, P; Maggi, CA; Renzi, D; Santicioli, P; Theodorsson, E | 1 |
| Alving, K; Lacroix, JS; Lundberg, JM; Martling, CR; Matran, R | 2 |
| Becher, G; Oehme, P; Rathsack, R; Schreiber, J; Slapke, J | 1 |
| Blazejczak, C; Ford-Hutchinson, AW; Hamel, R; Van den Brekel, A | 1 |
| Drazen, JM; Shore, SA | 1 |
| Sasaki, H; Sekizawa, K; Shimura, S; Takishima, T; Yamauchi, K; Yamaya, M; Zayasu, K | 1 |
| Andrews, PV; Helme, RD; Khalil, Z; Thomas, KL | 1 |
| Bény, JL; Brunet, PC; Huggel, H | 1 |
| Holzer-Petsche, U; Lembeck, F; Seitz, H | 1 |
| Donnerer, J | 1 |
| Harti, G; Pierau, FK; Sharkey, KA | 1 |
| Fujii, T; Morimoto, H; Senoh, H | 1 |
| Astolfi, M; Del Bianco, E; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Parlani, M; Patacchini, R; Santicioli, P | 1 |
| Marks, JG | 1 |
| De Benedetti, L; Geppetti, P; Maggi, CA; Manzini, S; Perretti, F; Pradelles, P | 1 |
| Borson, DB; Bridenbaugh, R; Gorman, C; Kohrogi, H; Malfroy, B; Nadel, JA; Patton, JS | 1 |
| Borson, DB; Djokic, TD; Dusser, DJ; Nadel, JA | 1 |
| Chorev, M; Devor, M; Gilon, C; Nachmias, E; Papir-Kricheli, D; Rosenthal, F; Selinger, Z | 1 |
| Jofre, A; Montoya, GA; Pezo, AA; Villena, F | 1 |
| Geppetti, P; Maggi, CA; Rubini, I; Santicioli, P; Sicuteri, F; Spillantini, MG | 1 |
| Franco-Cereceda, A; Rudehill, A | 1 |
| Hashiba, Y; Hidaka, H; Ishikawa, N; Satake, T; Sumita, T; Takagi, K | 1 |
| Ekman, R; Ekström, J; Håkanson, R; Luts, A; Sundler, F; Tobin, G | 1 |
| Borson, DB; Djokic, TD; Dusser, DJ; Jacoby, DB; Nadel, JA; Rubinstein, I | 1 |
| Bell, C; Gurusinghe, CJ | 1 |
| Dray, A; Hankins, MW; Yeats, JC | 1 |
| Abelli, L; Conti, S; Del Bianco, E; Geppetti, P; Maggi, CA; Manzini, S; Somma, V | 1 |
| Chahl, LA | 3 |
| Hill, CE; Vidovic, M | 1 |
| Cecconi, R; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Burnstock, G; Ellis, JL | 1 |
| Burcher, E; Lew, R; Mussap, CJ | 1 |
| Wolf, G | 1 |
| Ekman, R; Håkanson, R; Malm, L; Petersson, G | 1 |
| Abelli, L; Geppetti, P; Giuliani, S; Jancsó, G; Lippe, IT; Maggi, CA; Meli, A; Santicioli, P; Somma, V | 1 |
| Alber, G; Hammer, DK; Hartmann, A; Reck, B; Sailer-Kramer, B; Scheuber, PH | 1 |
| Dockray, GJ; Jamieson, A; Louis, SM; Russell, NJ | 1 |
| Brodin, E; Jonsson, G; Luthman, J; Strömberg, I | 1 |
| Barbanti, G; Beneforti, P; Maggi, CA; Meli, A; Patacchini, R; Rovero, P; Santicioli, P; Turini, D | 1 |
| Imai, Y; Inoki, R; Shibutani, T; Yonehara, N | 1 |
| Stapelfeldt, WH; Szurszewski, JH | 1 |
| Matsumoto, H | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Jaffe, JH; Sharpe, LG; Weinhold, LL | 1 |
| Baguñà, J; Romero, R; Saló, E | 1 |
| Maggi, CA; Meli, A; Santicioli, P | 2 |
| Akagi, H; Konishi, S; Otsuka, M; Yanagisawa, M | 1 |
| Papka, RE; Randić, M; Urbán, L; Willetts, J | 1 |
| Fischer, JA; Franco-Cereceda, A; Hökfelt, T; Hua, X; Lundberg, JM | 1 |
| Hedner, J; Hedner, T; Jonason, J | 1 |
| Emson, PC; Fitzgerald, M; Goedert, M; Wall, PD | 1 |
| Marshall, DA; Maruniak, JA; Mason, JR; Silver, WL | 1 |
| Buck, SH; Burks, TF; Miller, MS | 2 |
| Buchheit, KH; Engel, G; Mutschler, E; Richardson, B | 1 |
| Lembeck, F; Papka, RE; Saria, A; Traurig, H | 1 |
| Hua, X; Lundberg, JM; Saria, A; Skofitsch, G | 1 |
| Bynke, G; Håkanson, R; Wahlestedt, C | 1 |
| Conrath-Verrier, M; Dietl, M; Tramu, G | 1 |
| Fennessy, MR; Stewart, AG; Thompson, DC | 1 |
| Hori, T | 1 |
| Ishizuka, Y; Matsumiya, T; Oka, T; Sawa, A | 1 |
| Gamse, R; Holzer, P; Lembeck, F | 2 |
| Fibiger, HC; Nagy, JI; Reisine, TD; Staines, WA; Vincent, SR; Yamamura, HI | 1 |
| Bito, LZ; Camras, CB | 1 |
| Harmar, A; Keen, P; Schofield, JG | 1 |
| Hayes, AG; Tyers, MB | 1 |
| Butler, JM; Hammond, BR | 1 |
| Gamse, R; Jessell, TM; Leeman, SE; Mudge, AW; Yaksh, TL | 1 |
| Hack, U; Juan, H; Lembeck, F; Seewann, S | 1 |
| Placheta, P; Singer, E | 1 |
| Akagi, H; Otsuka, M; Yanagisawa, M | 1 |
| Hill, RG; Salt, TE | 1 |
| Haeusler, G; Osterwalder, R | 2 |
| Gamse, R; Lembeck, F; Mayer, N | 1 |
| Lembeck, F | 3 |
| Leeman, SE | 1 |
| Jessell, TM | 2 |
| Cuello, AC; Gamse, R; Holzer, P; Lembeck, F | 1 |
| Gamse, R; Leeman, SE; Wax, A; Zigmond, RE | 1 |
| Bernstein, JE; Lorincz, AL; Soltani, K; Swift, RM | 1 |
| Emson, PC; Iversen, LL; Nagy, JI | 1 |
| Bucsics, A; Lembeck, F | 1 |
| Carpenter, SE; Lynn, B | 1 |
| Brody, MJ; Gebhart, GF; Knuepfer, MM; McManus, DQ; Virus, RM | 1 |
| Donnerer, J; Lembeck, F | 3 |
| Buck, SH; Burks, TF; Deshmukh, PP; Miller, MS; Yamamura, HI | 1 |
| Gamse, G; Gamse, R; Lackner, D; Leeman, SE | 1 |
| Barber, P; Hoyes, AD | 1 |
| DiMicco, JA; Helke, CJ; Jacobowitz, DM; Kopin, IJ | 1 |
| Hayes, AG; Scadding, JW; Skingle, M; Tyers, MB | 1 |
| Dawbarn, D; Harmar, AJ; Pycock, CJ | 1 |
| Black, IB; Kessler, JA | 1 |
| Bill, A; Mandahl, A | 3 |
| Helke, CJ; Jacobowitz, DM; Thoa, NB | 1 |
| Gamse, R; Holzer, P; Leeman, SE; Lembeck, F | 1 |
| Emson, PC; Hunt, SP; Iversen, LL; Nagy, JI | 1 |
| Brown, M; Elde, R; Halász, N; Hökfelt, T; Jancsó, G; Kiraly, E; Lundberg, JM; Nilsson, G; Rehfeld, J; Said, S; Steinbusch, H; Terenius, L; Verhofstad, A | 1 |
| Folkers, K; Horig, J; Piercey, MF; Schroeder, LA; Xu, JC | 1 |
| Tervo, K | 1 |
| Barber, P; Hoyes, AD; Jagessar, H; Sikri, KL | 1 |
| Buck, SH; Burks, TF; Deshmukh, PP; Yamamura, HI | 1 |
| Costa, M; Della, NG; Furness, JB; Papka, RE | 1 |
| Ainsworth, A; Allt, G; Gibson, S; Hall, P; MacKenzie, ML; Polak, JM; Wall, PD | 1 |
| Barthó, L; Sebök, B; Szolcsányi, J | 1 |
| Schmid, R; Singer, EA; Sperk, G | 1 |
| Fujiwara, M; Muramatsu, I; Sakakibara, Y; Ueda, N | 1 |
| Bodnar, RJ; Kirchgessner, A; Mulhern, J; Nilaver, G; Zimmerman, EA | 1 |
| Cuello, AC; Matthews, MR | 2 |
| Costa, M; Della, NG; Eskay, RL; Furness, JB; Papka, RE | 1 |
| Gamse, R; Jancsò, G; Lembeck, F; Petsche, U | 1 |
| Butler, JM; Cole, DF; Ohara, K; Zhang, SQ | 1 |
| Eränkö, L; Tervo, K; Tervo, T | 1 |
| Blyth, WA; Hill, TJ; Keen, P; Tullo, AB | 1 |
| Masuda, K; Mochizuki, M; Nishiyama, A | 1 |
| Buck, SH; Burks, TF; Walsh, JH; Yamamura, HI | 1 |
| Crozier, CS; Hill, RG; Salt, TE | 1 |
| Buck, SH; Burks, TF; Miller, MS; Sipes, IG | 1 |
| Buck, SH; Duckles, SP | 1 |
| Gebhart, GF; McManus, DQ; Virus, RM | 2 |
| Louie, G; Tsou, K; Way, EL | 1 |
| Gamse, R | 1 |
| Bucsics, A; Holzer, P; Lembeck, F | 1 |
| Bond, SM; Cervero, F; McQueen, DS | 1 |
| Buck, SH; Burks, TF; Miller, MS; Sipes, IG; Yamamura, HI | 1 |
| Akagi, H; Konishi, S; Otsuka, M; Tsunoo, A; Yanagisawa, M | 1 |
| Fitzgerald, M; Wall, PD | 1 |
| Gamse, R; Lembeck, F | 1 |
| Cuello, AC; Matthews, MR; Priestley, JV | 1 |
| Fujiwara, M; Hayashi, H; Muramatsu, I; Ueda, N | 1 |
| Konishi, S; Otsuka, M; Tsunoo, A | 1 |
| Beardsley, AM; Costa, M; Furness, JB; Murphy, R | 1 |
| Kongsamut, S; Monsereenusorn, Y; Pezalla, PD | 1 |
| Brendel, K; Buck, SH; Burks, TF; Miller, MS | 1 |
| Chalmers, JP; Costa, M; Elliott, JM; Furness, JB; Murphy, R | 1 |
| Henry, JL; Wright, DM; Yasphal, K | 1 |
| Lundberg, JM; Saria, A | 2 |
| Emson, PC; Goedert, M; Nagy, JI | 1 |
| Chapman, D; Goedert, M; Hunt, SP; Iversen, LL; Nagy, JI | 1 |
| Barthó, L; Holzer, P; Lembeck, F; Szolcsányi, J | 1 |
| Businger, F; Lorez, HP; Otten, U | 1 |
| Colpaert, FC; Donnerer, J; Lembeck, F | 1 |
| Micevych, PE; Szolcsanyi, J; Yaksh, TL | 1 |
| Baccaglini, PI; Hogan, PG | 1 |
| Abay, EO; Go, VL; Micevych, PE; Schmauss, C; Yaksh, TL | 1 |
| Chahl, LA; Manley, SW | 1 |
| Atkinson, ME; Chaggar, JS | 1 |
| Fitzgerald, M | 1 |
| Brodin, E; Folkers, K; Lundberg, JM; Rosell, S; Saria, A | 1 |
| Aeppli, L; Haeusler, G; Lorez, HP | 1 |
| Donnerer, J; Lembeck, F; Petronijevic, S; Saria, A; Skofitsch, G | 1 |
| Bradley, WG; Chad, D; Good, P; Rasool, C; Reichlin, S | 1 |
| Foreman, J; Jordan, C | 1 |
| Bergstrom, L; Go, VL; Hammond, DL; Yaksh, TL | 1 |
| Foreman, JC; Jordan, CC; Oehme, P; Renner, H | 1 |
| Bynke, G; Håkanson, R; Hörig, J | 1 |
| Hunt, SP; Nagy, JI | 1 |
| Dun, NJ; Kiraly, M | 1 |
| Dib, B | 1 |
| Brown, MR; Buck, SH; Burks, TF; Davis, TP; Walsh, JH; Yamamura, HI | 1 |
| Brody, M; Liu-Chen, LY; Moskowitz, MA | 1 |
| Björkroth, U | 1 |
| Gallacher, DV | 1 |
| Dockray, GJ; Schultzberg, M; Sharkey, KA; Williams, RG | 1 |
| Hua, X; Lembeck, F; Lundberg, JM; Saria, A | 1 |
| Locatelli, V; Mantegazza, P; Martini, A; Panerai, AE | 1 |
| Lundberg, JM; Martling, CR; Saria, A | 1 |
| Anggård, A; Lundberg, JM; Lundblad, L | 1 |
| Lembeck, F; Lundberg, JM; Saria, A; Skofitsch, G | 1 |
| Brodin, E; Lundberg, JM; Saria, A | 1 |
| Folkers, K; Lundberg, JM; Martling, CR; Rosell, S; Saria, A | 1 |
| Laduron, PM | 1 |
| Costa, M; Della, NG; Furness, JB; Murphy, R; Papka, RE | 2 |
| Fujiwara, M; Muramatsu, I; Ueda, N | 2 |
| Cuello, C; Hökfelt, T; Lundberg, JM; Martling, CR; Saria, A | 1 |
| Engler, D; Lewis, SF; MacLean, DB | 1 |
| Dalsgaard, CJ; Dockray, GJ; Elfvin, LG; Hökfelt, T; Schultzberg, M; Terenius, L; Vincent, SR | 1 |
| Björklund, H; Olson, L; Seiger, A | 1 |
| Carter, DA; Lightman, SL | 1 |
| Brodin, E; Hua, X; Lundberg, JM; Saria, A | 1 |
| Fredholm, BB; Hua, Y; Lundberg, JM | 1 |
| Donnerer, J; Lembeck, F; Skofitsch, G | 1 |
| Holzer, P | 1 |
| Ito, S; Ohga, A; Seno, N | 1 |
| Bervoets, K; Colpaert, FC | 1 |
| Saria, A | 1 |
| Kigoshi, S; Muramatsu, I; Yamanaka, K | 1 |
| Barthó, L; Donnerer, J; Holzer, P; Lembeck, F | 1 |
| Skrabanek, P | 1 |
| Jones, DJ; Northam, WJ | 1 |
| Donnerer, J; Holzbauer, M; Holzer, P; Lembeck, F; Schluet, W; Sharman, DF | 1 |
| Go, VL; Harty, G; Jhamandas, K; Szolcsanyi, J; Yaksh, TL | 1 |
| Hunter, JC; Maggio, JE | 1 |
| Bynke, G; Håkanson, R; Sundler, F | 1 |
| Dockray, GJ; Sharkey, KA; Williams, RG | 1 |
| Anggård, A; Lundberg, JM; Lundblad, L; Saria, A | 1 |
| Lundblad, L | 1 |
| Hawcock, AB; Hayes, AG; Hill, RG | 1 |
| Lembeck, F; Saria, A; Traurig, H | 1 |
| Hildebrandt, J; Lai, YL; Lamm, WJ | 1 |
| Matsumiya, T; Oka, T; Sawa, A | 1 |
| Bell, C; Hurley, JV; Kenins, P | 1 |
| Dalsgaard, CJ; Dockray, GJ; Elde, R; Gustafsson, L; Hökfelt, T; Vincent, SR; Wiesenfeld-Hallin, Z | 1 |
| Bittner, MA; Lahann, TR | 1 |
| Chole, RA; Sherman, BE | 1 |
| Ansay, M; Delaunois, A; Garbarg, M; Gustin, P | 1 |
| Ahluwalia, A; Flower, RJ; Manzini, S; Perretti, M | 1 |
| Bertrand, C; Daffonchio, L; Geppetti, P; Huber, O; Nadel, JA; Omini, C; Yamawaki, I | 1 |
| Chariot, J; Dauge-Geffroy, MC; Laporte, JL; Potet, F; Rozé, C | 1 |
| Gerstberger, R; Pierau, FK; Rössler, W; Sann, H | 1 |
| Aikawa, T; Sasaki, H; Sekizawa, K; Ujiie, Y | 1 |
| Hukuda, S; Imai, S; Maeda, T | 1 |
| Lotti, T; Teofoli, P; Tsampau, D | 1 |
| Kanno, T; Matsumoto, S; Nagayama, T; Shimizu, T; Tanno, M; Yamasaki, M | 1 |
| Guo, JZ; Hagan, RM; Hosoki, R; Otsuka, M; Yanagisawa, M; Yoshioka, K | 1 |
| Grönbech, JE; Lacy, ER | 1 |
| Larson, AA; Sun, X | 3 |
| do Patrocínio, M; Dolhnikoff, M; Leme, AS; Martins, MA; Pereira, PM; Sakae, RS; Saldiva, PH; Warth, TN; Zin, WA | 1 |
| Hong, KW; Lee, WS; Pyo, KM; Rhim, BY; Yu, SS | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 5 |
| Abelli, L; Geppetti, P; Maggi, CA | 1 |
| Ellis, LC; Jones, MA; Marfurt, CF | 1 |
| Cragg, PA; Kou, YR; Prabhakar, NR | 1 |
| McDonald, DM; Sulakvelidze, I | 1 |
| Fukushima, T; Jin, Y; Morikawa, M; Nakazawa, H; Sasaki, H; Sekizawa, K | 1 |
| Larson, AA; Mousseau, DD; Sun, X | 1 |
| Christian, EP; Stow, RB; Talerico, SD; Turner, CR; Williams, JC | 1 |
| Lai, YL; Zhou, KR | 1 |
| Bacci, E; Baker, J; Bertrand, C; Geppetti, P; Laitinen, LA; Nadel, JA; Petersson, G | 1 |
| Bowie, D; Feltz, P; Schlichter, R | 1 |
| Besson, G; Drazen, JM; Israel, E; Lilly, CM; Rodger, IW | 1 |
| Davis, W; Eysselein, V; Mueller, K; Nast, C; Patel, A; Reinshagen, M; Sottili, M | 1 |
| Dymshitz, J; Vasko, MR | 2 |
| Galligan, JJ; Yunker, AM | 2 |
| Grider, JR; Jin, JG | 1 |
| Fiore, G; Fusco, BM; Gallo, F; Giacovazzo, M; Martelletti, P | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Banasiak, D; Burcher, E | 1 |
| Barnes, PJ; Belvisi, MG; Maggi, CA; Patacchini, R | 1 |
| Bassirat, M; Dusting, GJ; Helme, RD; Khalil, Z; Ralevic, V | 1 |
| Andersson, KE; Igawa, Y; Ishizuka, O; Mattiasson, A | 1 |
| Alkon, J; Coburn, RF; Dey, RD; Mitchell, H | 1 |
| Garry, MG; Hargreaves, KM; Richardson, JD | 1 |
| Ansay, M; Delaunois, A; Gustin, P | 2 |
| Calabrò, F; Chitano, P; Di Blasi, P; Fabbri, LM; Lucchini, RE; Maestrelli, P; Mapp, CE; Saetta, M | 1 |
| Brodecka, H; Glinska-Ferenz, M; Glinski, W; Kowalski, D | 1 |
| Czarnetzki, BM; Fechner, K; Furkert, J; Heinzelmann, T; Paus, R; Schultz, KD | 1 |
| De Sanctis, GT; Green, FH; Jiang, X; King, M; Remmers, JE | 1 |
| Nicolodi, M | 1 |
| Dubner, R; Ruda, MA; Thomas, DA | 1 |
| Dimaline, R; Dockray, GJ; Evans, D; Forster, E | 1 |
| Erion, MD; Gilligan, JP; Jeng, AY; Lovato, SJ | 1 |
| Kawaguchi, M; Maehara, K; Maruyama, Y; Saito, T; Sato, E; Yaoita, H | 1 |
| Blundell, D; Brauer, MM; Burnstock, G; Lincoln, J; Milner, P; Passaro, M; Sarner, S | 1 |
| Vanner, S | 1 |
| Holzer, P; Jocic, M | 1 |
| Katsumata, K; Kisara, K; Ohba, M; Sakurada, S; Sakurada, T; Tan-No, K; Yogo, H | 1 |
| Chen, IJ; Chen, SJ; Lo, YC; Wu, JR; Yang, JM; Yeh, JL | 1 |
| Barthó, L; Maggi, CA; Patacchini, R; Wilhelm, M | 1 |
| Abineau, P; Callebert, J; Dimitriadou, V; Farjaudon, N; Kacem, K; Launay, JM; Mathiau, P; Reynier-Rebuffel, AM; Seylaz, J | 1 |
| Coyle, AJ; Irvin, CG; Manzini, S; Perretti, F | 1 |
| Kitto, KF; Kreeger, JS; Larson, AA | 1 |
| Hersh, EV; Ochs, HA; Pertes, RA | 1 |
| Bertrand, C; Chan, B; Geppetti, P; Nadel, JA; Ricciardolo, FL; Yamawaki, I | 1 |
| Hosoki, R; Kurihara, T; Otsuka, M; Saito, K; Suzuki, H; Urayama, O; Yanagisawa, M; Yoshioka, K | 1 |
| Hingtgen, CM; Vasko, MR | 1 |
| Fujimiya, M; Kwok, YN | 1 |
| Demedts, MG; Pype, JL; Verleden, GM | 1 |
| Gairola, CG; Lai, YL; Thacker, A | 1 |
| Kuraishi, Y; Satoh, M; Sugimoto, K; Ueda, M | 1 |
| Ansay, M; Delaunois, A; Dessy-Doize, C; Gustin, P | 1 |
| Bevan, S; Geppetti, P | 1 |
| Cho, CH; Ko, JK; Tang, XL | 1 |
| Burg, M; Knuepfer, MM; Zahm, DS | 1 |
| Bolego, C; Pinna, C; Puglisi, L | 2 |
| Cutrer, FM; Garret, C; Moskowitz, MA; Moussaoui, S | 1 |
| Bric, JM; Joad, JP; Pinkerton, KE | 1 |
| Jiang, D; Li, Z; Zhang, R | 2 |
| Ahmed, M; Bjurholm, A; Kreicbergs, A; Lundeberg, T; Schultzberg, M; Srinivasan, GR; Theodorsson, E | 1 |
| Brain, SD; Newbold, P | 1 |
| Giuliani, S; Lecci, A; Maggi, CA; Meini, S | 1 |
| Alger, LE; Garland, A; Jordan, JE; Miller, RJ; Necheles, J; Ray, DW; Scully, MM; Solway, J; White, SR | 1 |
| Ballati, L; Boni, P; Evangelista, S | 1 |
| Gould, DJ; Hill, CE | 1 |
| Chiba, Y; Misawa, M | 1 |
| Gao, XP; Rubinstein, I | 1 |
| Fernezlian, SM; Leme, AS; Maldonado, EA; Martins, MA; Perini, A; Saldiva, PH; Warth, Mdo P | 1 |
| Hayashi, K; Kuraishi, Y; Nagasawa, T; Satoh, M | 1 |
| Henry, JL; Pitcher, GM; Yashpal, K | 1 |
| Chen, CF; Chien, CT; Lai, YL; Shiao, HL; Thacker, AA; Zhang, HQ | 1 |
| Basbaum, AI; DeMaster, E; Ghilardi, JR; Liu, H; Maggio, JE; Malhotra, A; Mantyh, CR; Mantyh, PW; Rogers, SD; Vigna, SR | 1 |
| Drazen, JM; Haley, KJ; Hall, AE; Kobzik, L; Lilly, CM; Rodger, IW | 1 |
| Davison, B; Ingenito, EP; Lilly, C; Mark, L | 1 |
| Chen, IJ; Chen, IS; Chen, SJ; Lo, YC; Wu, BN; Yeh, JL | 1 |
| Ferrell, WR; Karimian, SM; McDougall, JJ | 1 |
| Cioncolini, F; Figini, M; Geppetti, P; Javdan, P | 1 |
| Schneider, C; Spurlock, B; Stewart, NL; Szarek, JL | 1 |
| Brain, JD; Jimba, M; Killingsworth, CR; Long, NC; Shore, SA; Skornik, WA | 1 |
| Kobayashi, D; Okabe, E; Ozono, S; Todoki, K | 1 |
| Germonpre, PR; Joos, GF; Pauwels, RA | 1 |
| Barthò, L; Holzer, P; Maggi, CA; Patacchini, R | 1 |
| Bergren, D; Schultz, HD; Ustinova, EE | 1 |
| Hardwick, JC; Mawe, GM; Parsons, RL | 1 |
| Coupar, IM; Kerr, KP; Mitchelson, F | 1 |
| Holzer-Petsche, U; Rordorf-Nikolić, T | 1 |
| Folkerts, G; Ladenius, AR; Nijkamp, FP; van der Linde, HJ | 1 |
| Chodimella, V; Lang, Z; Murlas, CG | 1 |
| Connor, HE; O'Shaughnessy, CT; Waldron, GJ | 1 |
| Bosnjak, ZJ; Coon, RL; Flynn, NM; Tudoric, N | 1 |
| Abe, Y; Irifune, M; Kalubi, B; Matsunaga, T; Ogino, S; Takeda, N | 1 |
| Choi, SC; Garcia, CI; Kontos, HA; Levasseur, JE; Moskowitz, MA; Patterson, JL | 1 |
| Dray, A; Maggi, CA; Nagy, I; Urban, L; Woolf, CJ | 1 |
| Ikeda, H; Kitajiri, M; Kubo, N; Kumazawa, T; Sato, K | 1 |
| Chen, IJ; Lo, YC; Wang, Y; Yeh, JL | 1 |
| Mak, JC; Meini, S; Rogers, DF; Rohde, JA | 1 |
| Barnes, PJ; Hirayama, Y; Lei, YH; Rogers, DF | 1 |
| Larson, AA; Skilling, SR | 1 |
| Advenier, C; Molimard, M | 1 |
| Bertrand, C; Desai, MC; Hoffman, JI; Husseini, WK; Nadel, JA; Petersson, G; Piedimonte, G; Snider, RM | 1 |
| Advenier, C; Emonds-Alt, X; Qian, Y | 1 |
| Clavenna, G; Daffonchio, L; Hernandez, A; Melillo, G; Omini, C | 1 |
| Alleva, E; Aloe, L; Bigi, S; De Acetis, L; De Simone, R | 1 |
| Blanchard, JC; Carruette, A; Garret, C; Laduron, PM; Montier, F; Moussaoui, SM | 1 |
| Fazekas, A; Györfi, A; Irmes, F; Jakab, G; Rosivall, L; Sütö, T | 1 |
| Katsumata, K; Kisara, K; Sakurada, S; Sakurada, T; Tan-No, K; Yogo, H | 1 |
| Bueno, L; Fargeas, MJ; Fioramonti, J | 1 |
| Fujii, T; Hagiwara, D; Ikari, N; Maeda, Y; Matsuo, M; Miyake, H; Murai, M | 1 |
| Barnes, PJ; Crawley, D; Evans, TW; McCormack, DG; Rees, RG | 1 |
| Bertrand, C; Desai, MC; Geppetti, P; Nadel, JA; Piedimonte, G; Snider, RM | 1 |
| Desai, MC; Hoffman, JI; Husseini, WK; Nadel, JA; Piedimonte, G; Snider, RM | 1 |
| Garland, A; Hershenson, MB; Hsiue, TR; Leff, AR; Ray, DW; Solway, J | 1 |
| Berberian, B; Dodd, WA; Ellis, CN; Jarratt, MT; Katz, HI; Krueger, G; Prawer, S; Rex, IH; Sulica, VI; Wolf, JE | 1 |
| Barnes, PJ; Maclagan, J; Watson, N | 1 |
| Fujii, W; Namba, T; Suga, H; Takaki, M | 1 |
| Blumberg, PM; Conte, B; Goso, C; Manzini, S; Szallasi, A | 1 |
| Inoue, K; Kamata, K; Kasuya, Y | 1 |
| Anding, P; Gao, XP; Lowe, J; Rennard, SI; Robbins, RA; Rubinstein, I; Snider, RM | 1 |
| Uchida, M; Watanabe, K; Yano, S | 1 |
| Garret, C; Le Prado, N; Moussaoui, SM; Philippe, L | 1 |
| DeSautel, MG; Maher, JW; Sandler, AD; Schlegel, JF | 1 |
| Jew, JY; Maher, JW; Sandler, AD; Schlegel, JF; Schmidt, CD; Weinstock, JV; Williams, TH | 1 |
| Homma, I; Inoue, K; Sakai, Y | 1 |
| Fuchikami, J; Isohama, Y; Kai, H; Miyata, T; Takahama, K | 1 |
| Katori, M; Nishiyama, K; Ohno, T | 1 |
| Chen, J; Wu, S; Xu, C | 1 |
| Hall, JM; Mitchell, D; Morton, IK | 1 |
| Delay-Goyet, P; Lundberg, JM; Rinder, J; Satoh, H; Stjärne, P | 1 |
| Fujii, T; Hagiwara, D; Maeda, Y; Matsuo, M; Miyake, H; Murai, M; Yamaoka, M | 1 |
| Garret, C; Giuliani, S; Lecci, A; Maggi, CA | 1 |
| Dray, A; Maggi, CA; Nagy, I; Urban, L | 1 |
| Ando, R; Kawamura, S; Kume, H; Sakurada, T; Yonezawa, A | 1 |
| Nagy, J; Pethö, G; Szolcsányi, J | 1 |
| Lundeberg, T; Scarfone, E; Theodorsson, E; Ulfendahl, M | 1 |
| Bertrand, C; Geppetti, P; Graf, PD; Nadel, JA | 1 |
| Kurihara, T; Suzuki, H; Yanagisawa, M; Yoshioka, K | 1 |
| Baugh, LE; Farrell, AM; Kudlacz, EM; Logan, DE; Shatzer, SA | 1 |
| Katsumata, K; Kisara, K; Manome, Y; Ohba, M; Sakurada, S; Sakurada, T; Tan-No, K | 1 |
| Chen, IJ; Wu, SN; Yang, JM | 1 |
| Bryce, DK; Desai, MC; Ganong, A; Longo, KP; McLean, S; Reynolds, LS; Robinson, G; Rosen, T; Seymour, PA; Snider, RM | 1 |
| Fujii, T; Imazumi, K; Matsuda, A; Mizuhara, H; Morimoto, H; Ochi, T; Seki, N; Senoh, H; Yamashita, M | 1 |
| Everaert, E; Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA | 1 |
| Fuller, RW; Krausz, T; Moradoghli-Haftvani, A; O'Connell, F; Polak, JM; Price, D; Pride, NB; Springall, DR | 1 |
| Eran, M; Freier, S; Jarrah, S; Yefenof, E | 1 |
| Kido, MA; Kiyoshima, T; Kondo, T; Tanaka, T; Yamaza, T | 1 |
| Hong, S; Hwang, E; Jeon, S; Kim, N; Min, YG | 1 |
| Edvinsson, L; Jansen Olesen, I; Kingman, TA; McCulloch, J; Uddman, R | 1 |
| Beattie, DT; Brain, SD; Connor, HE; Escott, KJ | 1 |
| Blake, DR; Cruwys, SC; Garrett, NE; Jolliffe, VA; Kidd, BL; Mapp, PI | 1 |
| Doerfler, DL; Sailstad, DM; Selgrade, M; Veronesi, B | 1 |
| Ebihara, T; Nakazawa, H; Ohrui, T; Sasaki, H; Sekizawa, K | 1 |
| Ayata, C; Cutrer, FM; Lee, WS; Limmroth, V; Moskowitz, MA; Waeber, C; Yu, X | 1 |
| Gao, XP; Jaffe, HA; Olopade, CO; Rubinstein, I | 1 |
| Bee, D; Crambes, O; Howard, P; Laude, EA | 1 |
| Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA | 1 |
| Ikeda, K; Kubota, H; Miyata, K; Orita, A; Tomioka, K; Yamada, T | 1 |
| Coleman, JK; Miller, JM; Nuttall, AL; Vass, Z | 1 |
| Markle, RA; Walker, DK | 1 |
| Baluk, P; Bowden, JJ; Lefevre, PM; Lindsey, JR; McDonald, DM; Schoeb, TR | 1 |
| Beller, DI; Berman, AS; Black, PH; Chancellor-Freeland, C; Kage, R; Leeman, SE; Zhu, GF | 1 |
| Buck, H; Winter, J | 1 |
| Barber, LA; Vasko, MR | 1 |
| Matsuda, H; Miyatake, K; Nagata, S; Ohmori, F; Uematsu, M | 1 |
| Huang, HT; Huang, SH; Luor, YG | 1 |
| Blake, DR; Brain, SD; Cambridge, H; Kerslake, S; Mapp, PI | 1 |
| Chadwick, IG; Jackson, PR; Kraskiewicz, M; Ramsay, LE; Yeo, WW | 1 |
| Guan, X; Ouyang, X; Shi, J; Zhong, J; Zhou, J | 1 |
| Gur Aryeh, I; Niv, D | 1 |
| Hayashi, H; Katori, M; Majima, M; Nishiyama, K; Saigenji, K | 1 |
| Bian, RL; Chen, LP; Wang, YC; Wei, EQ; Xin, XH; Zhang, LF | 1 |
| Bolger, WE; Carlsöö, B; Norlander, T; Stierna, P; Uddman, R | 1 |
| Amann, R; Donnerer, J; Herzeg, G; Schuligoi, R | 1 |
| Hu, H; Jin, X | 1 |
| Bolton, M; Vanner, S | 1 |
| Back, SM; Hua, XY; Tam, EK | 1 |
| Eysselein, VE; French, S; Patel, A; Reinshagen, M; Sottili, M; Sternini, C | 1 |
| Bressan, AM; Perfumi, M; Piccoli, M; Santoni, G | 1 |
| Bowery, NG; Fowler, LJ; Malcangio, M; Teoh, H | 1 |
| Breschi, MC; Lazzeri, N; Martinotti, L; Nieri, P | 1 |
| Ackermann, L; Harvima, IT; Harvima, RJ; Horsmanheimo, M; Huttunen, M; Naukkarinen, A | 1 |
| Goehler, LE; Sternini, C | 1 |
| Kisara, K; Manome, Y; Sakurada, C; Sakurada, S; Sakurada, T; Tan-no, K; Wako, K | 1 |
| Spurlock, B; Szarek, JL | 2 |
| Dastmalchi, S; Gold, MS; Levine, JD | 1 |
| Wei, F; Zhao, ZQ | 1 |
| Fujii, T; Matsuda, A; Morimoto, H; Ohori, M | 1 |
| Tausk, F; Undem, B | 1 |
| Milot, M; Trudeau, F | 1 |
| Kuo, HC | 3 |
| Asztély, A; Ekman, R; Ekström, J; Tobin, G | 1 |
| Davis, AJ; Perkins, MN | 1 |
| Lundberg, JM; Rinder, J | 1 |
| Moskowitz, MA; Yu, XJ | 1 |
| Inoue, H; Koshihara, Y; Nagata, N; Shibata, S | 1 |
| Carlsson, PO; Jansson, L; Sandler, S | 1 |
| Lai, YL; Tai, HH; Zhang, HQ | 1 |
| Ghilardi, JR; Lapp, JA; Mantyh, CR; Mantyh, PW; Neville, LM; Pappas, TN; Rogers, SD; Vigna, SR; Washington, MK | 1 |
| Katakami, C; Kawakami, J; Yamamoto, M | 1 |
| Arakawa, M; Goto, F; Katori, M; Majima, M; Nagai, K | 1 |
| Baur, X; Marcynski, B; Marek, W; Potthast, JJ | 1 |
| Brechtelsbauer, PB; Miller, JM; Nuttall, AL; Vass, Z | 1 |
| Caldwell, RW; Chiao, H | 1 |
| Feuerstein, TJ; Gleichauf, O; Landwehrmeyer, GB | 1 |
| Bourdon, V; Damas, J; Liégeois, JF; Simmons, WH | 1 |
| Kummer, W; Myers, A; Undem, B | 1 |
| Buczko, W; Godlewski, G; Göthert, M; Malinowska, B | 1 |
| Kashiba, H; Senba, E; Ueda, Y | 1 |
| Buckley, TL; Muis, T; Nijkamp, FP; Scheerens, H; Van Loveren, H | 1 |
| Baluk, P; Bowden, JJ; Bunnett, NW; McDonald, DM | 1 |
| Alm, P; Andersson, KE; Johansson, K; Larsson, B; Persson, K | 1 |
| Boucher, RC; Costa, DL; Lehmann, JR; McCarty, D; Pickles, RJ; Piedimonte, G | 1 |
| Cho, YL; Huang, TP; Liu, HN; Tarng, DC | 1 |
| Ahluwalia, A; Vallance, P | 1 |
| Goldstein, BD; Yeomans, DC; Zachariou, V | 1 |
| Abadia-Molina, F; Burrows, NP; Munn, SE; Polak, JM; Russell Jones, R; Springall, DR | 1 |
| Grundemar, L; Håkanson, R; Waldeck, K; Wang, ZY | 1 |
| Cooke, HJ; Fox, P; Sidhu, M; Wang, YZ; Zimmermann, EM | 1 |
| Chen, IJ; Huang, WC; Lo, YC | 1 |
| Gilabert, R; McNaughton, P | 1 |
| Heyeraas, KJ; Jacobsen, EB | 1 |
| Duckett, S; Kradin, R; MacLean, J; Pinto, C; Schneeberger, EE; Waeber, C | 1 |
| Bai, T; Knight, D; McKay, K; Schellenberg, RR; Wiggs, B | 1 |
| Ansel, J; Bunnett, N; Emanueli, C; Figini, M; Geppetti, P; Gerard, C; Grady, EF; Kirkwood, K; Payan, DG | 1 |
| Holst, JJ; Schmidt, PT | 1 |
| Fujita, H; Kageyama, M; Nakata, K; Shirasawa, E | 1 |
| Advenier, C; Crambes, O; Girard, V; Lundberg, JM; Malbezin, M; Malmström, RE; Naline, E | 1 |
| Inaba, N; Kagoshima, M; Onodera, S; Shibata, M; Shimada, H; Suzuki, T; Yamaura, T | 1 |
| Fujii, T; Hirata, K; Kamoi, H; Kanazawa, H; Kawaguchi, T; Kudoh, S; Shoji, S; Yoshikawa, J | 1 |
| Goettl, VM; Larson, AA; Larson, DL; Portoghese, PS | 1 |
| Chen, P; Hua, XY; Hwang, J; Yaksh, TL | 1 |
| Berend, N; Matheson, MJ; McClean, MA; Rynell, AC | 1 |
| Ando, M; Fujii, K; Goto, E; Hamamoto, J; Hirata, N; Honda, I; Iwagoe, H; Kohrogi, H; Yamaguchi, T | 1 |
| Gonda, T; Hattori, K; Kakizoe, E; Kobayashi, Y; Okunishi, H; Shimoura, K | 1 |
| Brown, SI; Feldman, ST; Frucht-Pery, J | 1 |
| Cruwys, SC; Garrett, NE; Kidd, BL; Tomlinson, DR | 1 |
| Averbeck, B; Bickel, A; Luz, O; Schmelz, M | 1 |
| Juránek, I; Lembeck, F | 1 |
| Brodin, E; Petersen, LJ; Skov, PS; Winge, K | 1 |
| Buchanan, KD; Ferdinando, D; Green, MR; Johnston, C; Reilly, DM; Shaw, C | 1 |
| Homonko, DA; Marshall, KW; Theriault, E | 1 |
| Fujita, H; Kageyama, M; Kanai, A; Nakata, K; Shirasawa, E | 1 |
| Larkin, SW; Mitchell, JA; Williams, FM; Williams, TJ | 1 |
| Allen, BJ; Daughters, RS; Ghilardi, JR; Honore, P; Lappi, DA; Li, J; Mantyh, PW; Rogers, SD; Simone, DA; Wiley, RG | 1 |
| Bunnett, NW; Grady, EF; Martínez, V; Marvizón, JC; Mayer, EA | 1 |
| Cruwys, S; Garrett, NE; Malcangio, M; Tomlinson, DR | 1 |
| Aubineau, P; Delépine, L | 1 |
| Canver, CC; Cooler, SD; Saban, R | 1 |
| Andersson, RG; Lindström, EG | 1 |
| Calixto, JB; Cechinel Filho, V; de Campos, RO; Delle Monache, F; Pinheiro, TR; Pizzolatti, MG; Santos, AR; Vaz, ZR; Yunes, RA | 1 |
| Ritter, RC; Tamura, CS | 1 |
| MacNaughton, W; Moore, B; Vanner, S | 1 |
| Olszewski, MA; Robinson, NE; Zhang, XY; Zhu, FX | 1 |
| Alger, LE; Carson, SS; Garland, A; Leff, AR; McAllister, K; Necheles, J; Neeley, SP; Solway, J; White, SR | 1 |
| Advenier, C; Canet, E; Félétou, M; Girard, V | 1 |
| Doward, S; Foster, KA; Purkiss, JR; Welch, MJ | 1 |
| Gjerde, EA; Reed, RK; Woie, K | 1 |
| Blackshaw, LA; Dent, J | 1 |
| Bullock, GR; Joos, GF; Lefebvre, RA; Pauwels, RA | 1 |
| Amorena, M; D'Agostino, B; Loffreda, A; Lucisano, A; Marabese, I; Matera, MG; Rossi, F | 1 |
| Holst, JJ; Rasmussen, TN; Schmidt, PT | 2 |
| Appelgren, A; Appelgren, B; Bileviciute, I; Carleson, J; Kogner, P; Kopp, S; Lundeberg, T; Theodorsson, E; Yousef, N | 1 |
| Finkelstein, JB; Friedman, M; Gozal, D; Graham, RM; Hoyle, GW; Nguyen, KP | 1 |
| Ahluwalia, A; Kakuyama, M; Vallance, P | 1 |
| Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M | 1 |
| Egan, CL; Green, B; Murphy, GF; Trojanowski, JQ; Viglione-Schneck, MJ; Walsh, LJ; Whitaker-Menezes, D | 1 |
| Berti, F; Bianchi, M; Maggi, R; Panerai, AE; Rossoni, G | 1 |
| Didier, A; Igarashi, Y; Kaliner, MA; Kowalski, ML; Lundgren, JD | 1 |
| Douglas, SD; Ho, WZ; Lai, JP; Uvaydova, M; Zhu, XH | 1 |
| Carlsöö, B; Dahlqvist, A; Domeij, S; Lidegran, M | 1 |
| Dueck, R; Högman, M; Hua, XY; Reber, A; Yaksh, TL | 1 |
| Evangelista, S; Giachetti, A; Manzini, S; Paoli, S | 1 |
| Ishibashi-Ueda, H; Kawaguchi, AT; Kawashima, Y; Shirai, M; Yamano, M; Yamatodani, A | 1 |
| Cook, JA; Vilensky, JA | 1 |
| Blackshaw, LA; Lynn, PA; Smid, SD; Templeman, R | 1 |
| Chen, HB; Sasamoto, M; Tsukahara, S | 1 |
| Lai, LC; Lai, YL; Lin, CW | 1 |
| Helyes, Z; Németh, J; Oroszi, G; Pintér, E; Szolcsányi, J; Thán, M | 1 |
| Douglas, SD; Ho, WZ; Lai, JP | 1 |
| Nagai, A; Takeda, Y; Tamaoki, J; Yamawaki, I | 1 |
| Broberger, C; Elde, R; Hökfelt, T; Riedl, MS; Stone, LS; Vulchanova, L; Wilcox, GL | 1 |
| Fujibayashi, K; Kubota, K; Saito, K | 1 |
| Beckers, JF; Delaunois, A; Gustin, P; Nemmar, A; Sulon, J | 1 |
| Carle, F; Cinti, S; Gesuita, R; Giordano, A; Marchesi, GF; Morroni, M | 1 |
| Calixto, JB; Campos, MM; Cechinel Filho, V; Mendes, GL; Santos, AR; Tratsk, KS; Yunes, RA | 1 |
| Rees, H; Sluka, KA; Urban, L; Walpole, CJ; Willis, WD | 1 |
| Wei, F | 1 |
| Johnson, T; Kennedy, WR; Nolano, M; Simone, DA; Wendelschafer-Crabb, G | 1 |
| Page, CP; Shah, S; Spina, D | 1 |
| Fushiki, T; Inoue, K; Ishihara, K; Kawada, T; Kim, KM | 1 |
| Colquhoun, EQ; Eldershaw, TP; Geraghty, DP; Griffiths, CD | 1 |
| Bian, RL; Liu, JW; Wei, EQ; Zhang, LF; Zhang, WP | 1 |
| Gruetter, CA; Lemke, S; Spurlock, B; Szarek, JL | 1 |
| Ezaki, O; Inoue, S; Kimura, S; Kobayashi, A; Lee, TH; Namba, Y; Osaka, T | 1 |
| Bonanno, G; Carità, F; Raiteri, M; Schmid, G | 1 |
| Ansel, JC; Armstrong, CA; Bunnett, NW; Harten, B; Letran, E; Olerud, JE; Quinlan, KL; Song, IS; Steinhoff, M; Wright Caughman, S | 1 |
| Kopp, UC; Matsushita, K; Sigmund, RD; Smith, LA; Stokes, JB; Watanabe, S | 1 |
| Chen, HH; Kuo, HP | 1 |
| Kang, JY; Tu, Y | 1 |
| Fujiwara, H; Hirata, K; Kanazawa, H; Yoshikawa, J | 1 |
| Farkas-Szallasi, T; Hökfelt, T; Krause, JE; Lundberg, JM; Szallasi, A; Tucker, JB | 1 |
| Carter, JD; Devlin, RB; Oortgiesen, M; Veronesi, B | 1 |
| Fernandes, K; Malcangio, M; Tomlinson, DR | 1 |
| Kitto, KF; Larson, AA | 1 |
| Guo, JZ; Otsuka, M; Yoshioka, K | 1 |
| Ansel, JC; Armstrong, CA; Bunnett, NW; Caughman, SW; Letran, EL; Naik, SM; Olerud, JE; Quinlan, KL; Song, IS | 1 |
| Pierau, FK; Sann, H | 1 |
| Arcaya, JL; Cano, G; Gómez, G; Maixner, W; Suárez-Roca, H | 2 |
| Green, JF; Harkema, JR; Hyde, DM; Schelegle, ES; Stovall, MY; Vesely, KR | 1 |
| Ito, S; Minami, T | 1 |
| Baluk, P; Bunnett, NW; McDonald, DM; Murphy, TJ; Thurston, G | 1 |
| Corsi, MM; Dib, B; Falchi, M; Ferrero, ME; Fulgenzi, A | 1 |
| Bakhle, YS; Bell, C; Brogan, JD | 1 |
| Buckingham, JC; Kennard, C; Rhodes, KF | 1 |
| Mori, M; Tsushima, H | 1 |
| Cho, TS; Jung, YS; Lee, B; Lee, SM; Moon, CH; Shin, HS | 1 |
| Dirig, DM; Yaksh, TL | 1 |
| Kreulen, DL; Travagli, RA; Zheng, ZL | 1 |
| Fujihara, T; Nakata, K; Yoshida, A | 1 |
| Abel, PW; Bockman, CS; Smith, DD; Waugh, DJ | 1 |
| Beckers, JF; Bloden, S; Delaunois, A; Gustin, P; Nemmar, A; Sulon, J | 1 |
| Nielsen, JB; Petersen, T; Schrøder, HD | 1 |
| Inoue, M; Ueda, H; Yamada, T | 1 |
| Perfumi, MC; Piccoli, M; Romagnoli, S; Santoni, G; Spreghini, E | 1 |
| Başak, S; Metin, KK; Sarierler, M; Türkütanit, S | 1 |
| Levi, R; Maruyama, R; Seyedi, N | 1 |
| Gabaldón, M; Marqués, A | 1 |
| Helliwell, R; McIntyre, P; Ogun-Muyiwa, P; Winter, J | 1 |
| Huang, HT; Hwang, T; Tsao, CF | 1 |
| Bunnett, NW; Calaustro, EQ; Debas, HT; Domush, C; Grady, EF; He, XD; Kim, EH; Kirkwood, KS; Maa, J; Yoshimi, SK | 1 |
| Brain, SD; Cao, T; Gerard, NP | 1 |
| Heuven-Nolsen, D; Kraneveld, AD; Nijkamp, FP; van der Avoort, LA; van Houwelingen, A | 1 |
| Alexacos, N; Letourneau, R; Pang, X; Singh, LK; Theoharides, TC | 1 |
| Arcaya, JL; Cano, G; Cuesta, MC; Maixner, W; Sanchez, L; Suarez-Roca, H | 1 |
| Beckers, JF; Delaunois, A; Dessy-Doizé, C; Gustin, P; Nemery, B; Nemmar, A; Sulon, J | 1 |
| Baroody, FM; Corey, JP; Gungor, A; Naclerio, RM; White, SR | 1 |
| Exintaris, B; Lang, RJ | 1 |
| Coffa, FP; Kotecha, N | 1 |
| Mustafa, S; Oriowo, MA | 1 |
| Broome, CS; Miyan, JA; Whetton, AD | 1 |
| Carter, JD; Devlin, RB; Oortgiesen, M; Simon, SA; Veronesi, B | 1 |
| Lisney, SJ; Massey, EJ; Perry, MJ; Raven, PE; Scott, C | 1 |
| Adam, C; Baroukh, B; Cherruau, M; Llorens, A; Saffar, JL | 1 |
| Aloe, L; Lundeberg, T; Manni, L; Tirassa, P | 1 |
| Inoue, M; Mishina, M; Ueda, H | 1 |
| Potargowicz, E; Traczyk, WZ | 1 |
| Geraghty, DP; Mazzone, SB | 2 |
| Doward, S; Foster, K; Purkiss, J; Welch, M | 1 |
| Bellinger, DL; Engan, C; Felten, DL; Lorton, D; Lubahn, C; Schaller, J | 1 |
| Barthó, L; Benkó, R; Lázár, Z; Lénárd, L; Maggi, CA; Penke, B; Szolcsányi, J; Tóth, G | 1 |
| Holst, JJ; Poulsen, SS; Rasmussen, TN; Schmidt, PT; Tornøe, K | 1 |
| Ito, S; Minami, T; Mishina, M; Mori, H; Okuda-Ashitaka, E; Sakimura, K; Watanabe, M | 1 |
| Cervero, F; De Felipe, C; Hunt, SP; Laird, JM; Olivar, T; Roza, C | 1 |
| Ito, T; Kawai, Y; Tamura, T; Yonehara, N; Yoshimura, M | 1 |
| Farkas, B; Helyes, ZS; Németh, J; Oroszi, G; Pintér, E; Szolcsányi, J; Thán, M | 1 |
| Bobrowski, P; Charbonnet, RM; Lao, J; MacNaughton, WK; Miller, MJ; Sandoval, M; Thompson, JH; Trentacosti, AM; Zhang, XJ | 1 |
| Adelson, DW; Kruger, L; Maidment, NT; Matsuka, Y; Neubert, JK; Spigelman, I | 1 |
| Albright, GM; Hosaka, M; Janz, R; Li, JL; Richardson, JA; Shelton, JM; Südhof, TC; Victor, RG; Zhang, W | 1 |
| Hondo, E; Kitamura, N; Nishi, Y; Otani, M; Taguchi, K; Yamada, J | 1 |
| Furue, H; Kumamoto, E; Li, YQ; Yang, K; Yoshimura, M | 1 |
| Ackermann, MR; Gallup, JM; Ramírez-Romero, R; Sonea, IM | 1 |
| Douglas, SD; Ho, W; Li, Y | 1 |
| Chiba, T; Ino, H; Moriya, H; Murata, Y; Ohtori, S; Sameda, H; Takahashi, K; Yamagata, M | 1 |
| Bonham, AC; Joad, JP; Mutoh, T | 1 |
| Bunnett, NW; Grady, EF; Hutter, MM; Kim, EH; Kirkwood, KS; Maa, J; Yoshimi, SK | 1 |
| Kim, D; Moore, BA; Vanner, S | 1 |
| Cooper, BY; Gu, JG; Johnson, RD; Napaporn, J; Petruska, JC | 1 |
| Amadesi, S; Ansel, JC; Armstrong, CA; Bonaccorsi, P; Bunnett, NW; Geppetti, P; Gerard, NP; Grady, EF; Klein, R; Lu, B; Luger, TA; Olerud, JE; Scholzen, TE; Steinhoff, M | 1 |
| Amadesi, S; Bianchi, A; Carreras, M; Creminon, C; Geppetti, P; Harrison, S; Matera, M; Tognetto, M; Trevisani, M | 1 |
| Blakeman, KH; Ernfors, P; Hao, JX; Hassani, H; Lucas, G; Naveilhan, P; Thorén, P; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Luger, T; Metze, D; Ständer, S | 1 |
| Furuya, K; Kawakami, Y; Takahashi, T; Yamaguchi, E | 1 |
| Baird, AW; Goldhill, J; Moriarty, D; Selve, N | 1 |
| Avelino, A; Cruz, F | 1 |
| Katzman, NJ; Lai, YL | 1 |
| Yonehara, N; Yoshimura, M | 1 |
| Araki, H; Arizono, N; Kakehi, K; Kawabata, A; Kinoshita, M; Kuroda, R; Nishida, M; Nishikawa, H; Oda, Y | 1 |
| Choi, SS; Chung, KM; Lee, KC; Suh, HW | 1 |
| Antunes, E; De Luca, IM; De Nucci, G; Hyslop, S; Macedo-Soares, MF; Medeiros, MV | 1 |
| Adelson, DW; Bradbury, EJ; Cunningham, JR; Jones, MG; Lever, IJ; Malcangio, M; Marvizón, JC; McMahon, SB | 1 |
| Hsu, TH; Kou, YR | 1 |
| Carstens, E; Dessirier, JM; Jinks, SL; Simons, CT | 1 |
| Gillard, SE; Hammond, DL; Hurley, RW; Miller, RJ; Oh, SB; Tran, PB | 1 |
| Manning, BP; Mawe, GM | 1 |
| Bradbury, EJ; Charbel Issa, P; Lever, IJ; Malcangio, M; Michael, GJ | 1 |
| Baird, AW; Goldhill, J; Moriarty, D; O'Donoghue, DP; Selve, N | 1 |
| Hayashi, K; Ishii, A; Kaise, T; Karasawa, A; Ohmori, K; Sano, J; Sato, H | 1 |
| McVey, DC; Vigna, SR | 1 |
| Antunes, E; Brain, SD; Camargo, EA; Costa, SK; de Nucci, G; Esquisatto, LC; Ribela, MT | 1 |
| Averbeck, B; Cirillo, R; Evangelista, S; Fetzer, S; Kress, M; Lippi, A; Maggi, CA; Manzini, S; Reeh, PW; Sauer, SK; Vieira, C | 1 |
| Elde, R; Fairbanks, CA; Guo, A; Simone, DA; Stone, LS; Wang, J | 1 |
| Cai, Y; Kovacs, KJ; Larson, AA | 1 |
| Maidment, NT; Matsuka, Y; Neubert, JK; Spigelman, I | 1 |
| Liddle, RA; McVey, DC; Nathan, JD; Patel, AA; Prpic, V; Thomas, JE; Vigna, SR | 1 |
| Ansel, JC; Aranda, J; Armstrong, CA; Burbach, GJ; Caughman, SW; Kim, A; Kim, KH; Naik, SM; Wright, S; Zivony, AS | 1 |
| Bingol-Kologlu, M; Büyükpamukçu, N; Gedikoglu, G; Sarioglu, A; Tanyel, FC | 1 |
| Brain, SD; Cao, T; Gerard, NP; Grant, AD | 1 |
| Afrah, AW; Brodin, E; Gustafsson, H; Olgart, L; Stiller, CO | 1 |
| Hayashi, I; Kamijo, Y; Majima, M; Ohwada, T; Soma, K | 1 |
| Huang, HT; Ko, CC; Tsao, CF; Tseng, WY | 1 |
| Lever, IJ; Malcangio, M | 1 |
| Collins, JJ; McCarson, KE; Papka, RE; Usip, S | 1 |
| Ikeda, M; Kodama, H; Matsumoto, M; Morimoto, A; Seike, M | 1 |
| Greenwood-Van Meerveld, B; Sutkowski-Markmann, DM; Venkova, K | 1 |
| Kajekar, R; Myers, AC; Undem, BJ | 1 |
| Carini, F; Catalioto, RM; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
| Horvath, P; Kovács, P; Németh, J; Sziklai, I; Szilasi, M; Szilvássy, J; Szilvássy, Z | 1 |
| Eysselein, VE; Gerken, G; Goebell, H; Hoffmann, P; Holtmann, G; Mazurkiewicz, J | 1 |
| Amadesi, S; Barbieri, M; Bianchi, A; Brough, SJ; Campi, B; Davis, JB; Geppetti, P; Gray, J; Gunthorpe, MJ; Harrison, S; Jerman, JC; Owen, D; Randall, AD; Smart, D; Smith, GD; Tognetto, M; Trevisani, M | 1 |
| Willis, WD | 1 |
| MacNaughton, WK; Miceli, P; Morris, GP; Vanner, S | 1 |
| Herbert, MK; Holzer, P | 1 |
| Marsella, R; Melloy, C; Nicklin, CF | 1 |
| Ito, N; Miura, M; Sano, M; Sasaki, M; Shioya, T; Watanabe, A | 1 |
| Carstens, E; Gogineni, AG; Iodi Carstens, M; Simons, CT | 1 |
| Ashton, D; Fransen, JF; Hens, KA; Heylen, L; Hillen, LC; Janssens, F; Jurzak, MR; Leysen, JE; Mahieu, M; Megens, AA; Vermeire, JC; Vermote, PC | 1 |
| Cai, Y; Evensjö, M; Kovács, KJ; Larson, AA; McCarson, KE; Shi, Q; Velázquez, RA | 1 |
| Arai, H; Orui, T; Sasaki, H; Yamaya, M | 1 |
| Kyrkanides, S; Macher, DJ; Olschowka, JA; Stevens, SY; Tallents, RH | 1 |
| Itoh, M; Iwata, F; Kao, J; Leung, FW; Leung, JW; Seno, K | 1 |
| Ghilardi, JR; Khasabov, SG; Mantyh, PW; Peters, CM; Rogers, SD; Simone, DA | 1 |
| Crane, LH; Hamlin, GP; Nimmo, AJ; Williams, MJ | 1 |
| Ishida, Y; Murakami, S; Shimada, S; Ueda, T; Ugawa, S | 1 |
| Helyes, Z; Jakab, B; Németh, J; Pintér, E; Szolcsányi, J; Thán, M | 1 |
| Helyes, Z; Jakab, B; Németh, J; Oroszi, G; Pintér, E; Szilvássy, Z; Szolcsányi, J | 1 |
| Adriaensen, D; Brouns, I; Burnstock, G; Gajda, M; Gomi, T; Hayashi, H; Timmermans, JP; Van Genechten, J | 1 |
| Calo, G; Inoue, A; Inoue, M; Kawashima, T; Nakata, Y; Takeshima, H; Ueda, H | 1 |
| Harty, RF; Mesiya, S; Saymeh, L; Vongthavaravat, V; Xia, Y | 1 |
| Bayer, MK; Chavolla-Calderón, M; Fontán, JJ | 1 |
| Marvizón, JC; Matsuka, Y; Neubert, JK; Spigelman, I; Wang, X | 1 |
| Adler, JE; Resta, C; Skoff, AM; Swamydas, M | 1 |
| Dey, RD; Satterfield, BE; Wu, ZX | 1 |
| Aigueperse, J; Linard, C; Marquette, C; Mathe, D; Strup, C | 1 |
| Iwata, F; Leung, FW; Leung, JW; Seno, K | 1 |
| Kline, RH; Vierck, CJ; Wiley, RG | 1 |
| Adriaensen, D; De Jonge, F; Miller, HR; Timmermans, JP; Van Marck, E; Van Meir, F; Van Nassauw, L | 1 |
| Baamonde, A; Candenas, ML; Hidalgo, A; Pennefather, JN; Pintado, CO; Pinto, FM; Sanchez, T | 1 |
| Shea-Donohue, T; Zhao, A | 1 |
| Kawahara, M; Nakamura, M; Nakata, K; Nishida, T | 1 |
| Ahmed, S; Yuan, J | 1 |
| Bolle, P; Severini, C; Tucci, P; Valeri, P | 1 |
| Davies, C; Harrison, NK; Hilldrup, S; Hope-Gill, BD; Newton, RP | 1 |
| Choi, SS; Han, EJ; Han, KJ; Lee, HK; Suh, HW | 1 |
| Brock, JA; Dunn, WR; Hardy, TA | 1 |
| Foster, DE; Keith, I; Kweon, CB; Schauer, JJ; Sun, NN; Witten, ML; Wong, SS | 1 |
| GASPAROVIC, I; HADZOVIC, S; HUKOVIC, S; STERN, P | 1 |
| Gustafsson, H; Hole, K; Kjørsvik Bertelsen, A; Stiller, CO; Tjølsen, A; Warsame Afrah, A | 1 |
| Cho, YS; Lee, CK; Moon, HB; Park, SY; Yoo, B | 1 |
| Gear, RW; Levine, JD; Tambeli, CH; Young, A | 1 |
| Forsberg, E; Gjerde, EA; Iversen, VV; Karlsen, TV; Kjellén, L; Reed, RK | 1 |
| Chen, MJ; Lai, YL; Yu, SC | 1 |
| Brain, SD; Gerard, NP; Grant, AD; Lever, IJ; Malcangio, M; Pezet, S | 1 |
| Gaus, S; Kawamoto, M; Moriwaki, K; Suyama, H; Yuge, O | 1 |
| Feldman, JL; Morgado-Valle, C | 1 |
| Cunha-Vaz, JG; Gaspar, MN; Macedo, TR; Ribeiro, CA | 1 |
| Benvenuti, F; Campi, B; Creminon, C; Dinh, QT; Emonds-Alt, X; Fischer, A; Gazzieri, D; Geppetti, P; Groneberg, DA; Harrison, S; Rigoni, M; Trevisani, M | 1 |
| Lee, LY; Ruan, T; Wu, ZX; Yang, QH | 1 |
| Chuaychoo, B; Kollarik, M; Lee, MG; Myers, AC; Undem, BJ; Weinreich, D | 1 |
| Artuc, M; Brzoska, T; Buddenkotte, J; Henz, BM; Lippert, U; Luger, TA; Metze, D; Moormann, C; Schumacher, M; Shpacovitch, V; Ständer, S; Steinhoff, M | 1 |
| Anton, PM; Buéno, L; Eutamène, H; Fioramonti, J; Larauche, M; Peiro, G | 1 |
| Amantini, C; Lucciarini, R; Perfumi, M; Piccoli, M; Pompei, P; Santoni, G | 1 |
| Greenwood-Van Meerveld, B; Venkova, K | 1 |
| Amadesi, S; Bunnett, NW; Cottrell, GS; Davis, JB; Ennes, H; Geppetti, P; Grady, EF; Manni, C; Mayer, EA; McRoberts, JA; Nie, J; Trevisani, M; Vergnolle, N | 1 |
| Bowles, WR; Harding-Rose, C; Hargreaves, KM; Sabino, M | 1 |
| Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Yamashita, M | 1 |
| Atweh, SF; Jabbur, SJ; Massaad, CA; Poole, S; Saadé, NE; Safieh-Garabedian, B | 1 |
| Carlton, SM; Castañeda-Hernandez, G; Du, J; Grady, JJ; Jimenez-Andrade, JM; Yamani, A; Zhou, S | 1 |
| Keith, I; Sun, NN; Witten, ML; Wong, SS | 1 |
| Angel, F; Aunis, D; Crenner, F; Ghia, JE; Metz-Boutigue, MH | 1 |
| Clawson, GA; Erin, N | 1 |
| Arck, PC; Dinh, QT; Fischer, A; Groneberg, DA; Joachim, RA; Klapp, BF; Peiser, C; Springer, J | 1 |
| Brodin, E; Gustafsson, H; Olgart, L; Stiller, CO; Taylor, BK; Warsame Afrah, A | 1 |
| Neuhuber, WL; Tiegs, G | 1 |
| Befort, K; Brenner, GJ; Ji, RR; Kawasaki, Y; Kohno, T; Van Der Meer, C; Wang, H; Woolf, CJ; Zhuang, ZY | 1 |
| Burette, A; Hwang, SJ; Rustioni, A; Valtschanoff, JG | 1 |
| Goldie, RG; Hay, DW; Myers, AC | 1 |
| Kadowaki, M; Kuramoto, H; Takaki, M | 1 |
| Harrison, NK | 1 |
| Azuero-Holguin, MM; Caviedes-Bucheli, J; Munoz, HR | 1 |
| Newcombe, RG | 1 |
| Doblinger, A; Dragosits, E; Fischer-Colbrie, R; Göttinger, W; Humpel, C; Kunze, C; Lalehabbasi, D; Laslop, A; Leierer, J; Philipp, W; Schmid, E; Teuchner, B; Theodorsson, E; Troger, J | 1 |
| Gillespie, JI | 1 |
| Clark, JD; Guo, TZ; Jacobs, CR; Kingery, WS; Lane, NE; Lindsey, DP; Offley, SC; Vogel, H; Wei, T; Yao, W | 1 |
| Chancellor, MB; de Groat, WC; Erickson, KA; Igawa, Y; Nishizawa, O; Ogawa, T; Seki, M; Seki, S; Yoshimura, N | 1 |
| Wang, DH | 1 |
| Inoue, A; Kawamoto, M; Nakata, Y; Oshita, K; Tang, HB; Yuge, O | 1 |
| Donnerer, J; Liebmann, I; Lippe, IT; Schicho, R | 1 |
| Fu, LW; Longhurst, JC; Syuu, Z; Tjen-A-Looi, SC; Zhou, W | 1 |
| Nies, M; Ro, JY; Zhang, Y | 1 |
| Basak, S; Dikicioglu, E; Sarierler, M; Turkutanit, S | 1 |
| Bell, EB; Beresford, LJ; Miyan, JA; Shepherd, AJ | 1 |
| Bucala, R; Iczkowski, KA; Leng, L; Meyer-Siegler, KL; Vera, PL | 1 |
| Elekes, K; Helyes, Z; McDougall, JJ; Németh, J; Pintér, E; Szabó, A; Szolcsányi, J; Varga, A; Zhang, C | 1 |
| Bölcskei, K; Börzsei, R; Elekes, K; Helyes, Z; Jakab, B; Keszthelyi, D; Németh, J; Petho, G; Pintér, E; Sándor, K; Szabó, A; Szolcsányi, J; Varga, A | 1 |
| Fujiuchi, A; Hara, T; Imai, A; Kanai, Y; Nakazato, E | 1 |
| Gupta, J; Hayashi, F; Hayashi, M; Iino, T; Nakae, K; Yamamoto, N; Yoshikawa, S | 1 |
| Canning, BJ; Mazzone, SB; Mori, N | 1 |
| Easton, AS; Fraser, PA; Hu, DE | 1 |
| Ohrui, T | 1 |
| Abe, T; Arisaka, O; Morimoto, H; Ohori, M; Yamada, Y; Yoshihara, S | 1 |
| Ekman, R; Ekström, J | 1 |
| Ahern, GP; O'Connell, PJ; Pingle, SC | 1 |
| Kato, M; Kuramasu, A; Mobarakeh, JI; Orito, T; Sakurada, S; Sakurai, E; Yanai, K; Yoshida, A | 1 |
| Fujimura, T; Hayashi, T; Katsuyama, S; Mizoguchi, H; Nakayama, D; Sakurada, S; Sakurada, T; Sakurada, W; Sawai, T; Watanabe, C; Watanabe, H; Yuhki, M | 1 |
| Brain, SD; Costa, SK; Muscará, MN; Poston, RN; Yshii, LM | 1 |
| Clapp, DW; Hingtgen, CM; Roy, SL | 1 |
| Wang, DH; Wang, L | 1 |
| Kollarik, M; MacGlashan, DW; Taylor-Clark, TE; Undem, BJ | 1 |
| Bunnett, NW; Divino, LA; Grady, EF; Grahn, SW; Hoge, SG; Kim, E; Kirkwood, KS; Wick, EC | 1 |
| Fraser, MO; Pezzone, MA; Ustinova, EE | 1 |
| Aita, M; Maeda, T; Seo, K; Takagi, R | 1 |
| Akamatsu, Y; Hosokawa, N; Igarashi, M; Kubota, Y; Masuda, T; Nakae, K; Nakagawa, N; Nishimura, Y; Ohba, S; Sawa, R | 1 |
| Bylander, J; Chase, G; Clawson, G; Erin, N; Zhao, W | 1 |
| Cavalcante, IJ; Lima, MA; Maia, JL; Melo, CM; Rao, VS; Santos, FA; Silveira, ER; Vieira, GA | 1 |
| Hald, A; Inoue, M; Matsumoto, M; Ueda, H; Yamaguchi, A | 1 |
| Hide, I; Inoue, A; Iwasa, M; Nakata, Y; Tang, HB | 1 |
| DeHate, RB; Richards, IS | 1 |
| Horie, S; Keir, S; Michael, GJ; Page, CP; Priestley, JV; Spina, D; Watanabe, N | 1 |
| McDougall, JJ; Zhang, C | 1 |
| Bhatia, M; Moore, PK; Ng, SW; Zhang, H; Zhi, L | 1 |
| Gutkin, DW; Pezzone, MA; Ustinova, EE | 1 |
| Elekes, K; Helyes, Z; Németh, J; Pintér, E; Pozsgai, G; Reglödi, D; Szabó, A; Szolcsányi, J | 1 |
| Azuma, YT; Matsui, M; Nakajima, H; Takeuchi, T; Tanaka, K | 1 |
| Nakata, Y; Tang, HB | 2 |
| Chang, LW; Chen, SC; Tsai, MH; Wang, HJ; Yu, HS | 1 |
| Hughes, MG; McAdoo, DJ; Sun, RQ; Willis, WD; Yan, JY | 1 |
| Bletsa, A; Gjerde, EA; Karlsen, TV; Reed, RK | 1 |
| Afifiyan, FN; Chan, Y; Dosch, HM; Driver, JP; Liu, XJ; Razavi, R; Salter, MW; Santamaria, P; Serreze, D; Tang, L; Tsai, S; Tsui, H; Wan, X; Yantha, J | 1 |
| Budai, D; Khasabov, SG; Mantyh, PW; Simone, DA | 1 |
| Huang, F; Li, ZZ; Liu, Z; Wang, HJ; Wang, LH; Xing, Y | 1 |
| Dömötör, A; Hunyady, B; Kereskay, L; Mózsik, G; Szekeres, G; Szolcsányi, J | 1 |
| Börzsei, R; Elekes, K; Helyes, Z; Kereskai, L; Németh, J; Pintér, E; Pozsgai, G; Sándor, K; Szabó, A; Szolcsányi, J | 1 |
| de Groat, WC; Sculptoreanu, A | 1 |
| Bíró, T; Dobrosi, N; Géczy, T; Marincsák, R; Paus, R; Tóth, BI | 1 |
| Fachinetto, R; Maffi, LC; Meotti, FC; Missau, FC; Pizzolatti, MG; Rocha, JB; Santos, AR | 1 |
| Assini, JB; Blennerhassett, MG; Dilworth, N; Lourenssen, S; Miller, DV; Paterson, WG | 1 |
| Contet-Audonneau, JL; Danoux, L; Pauly, G; Rodeau, JL; Schlichter, R; Ulmann, L | 1 |
| Jesse, CR; Nogueira, CW; Pinto, LG; Rocha, JB; Savegnago, L; Zeni, G | 1 |
| Dolly, JO; Lawrence, G; Meng, J; Wang, J | 1 |
| Li, ZZ; Liu, HX; Liu, Z; Ma, CH; Wang, LH; Yang, XD | 1 |
| Kawana, S; Yamaoka, J | 1 |
| de Groat, WC; Sculptoreanu, A; Yamane, H | 1 |
| Ikeura, T; Kataoka, Y; Mori, T; Okazaki, K; Takamido, S; Takamori, Y; Wakabayashi, T; Yamada, H | 1 |
| Kajekar, R; Myers, AC | 1 |
| Davidson, ME; Lang, RJ | 1 |
| Costa, DL; Haykal-Coates, N; Hazari, MS; Ledbetter, AD; Rowan, WH; Watkinson, WP; Winsett, DW | 1 |
| Fang, L; Li, D; Lin, Q; Xu, X; Zou, X | 1 |
| Li, YS; Nakata, Y; Tang, HB | 1 |
| Brain, SD; Kofler, B; Schmidhuber, SM; Starr, A; Wynick, D | 1 |
| Feng, NH; Lee, HH; Ma, MC; Shiang, JC | 1 |
| Cao, DY; Chen, Z; Seltzer, Z; Sun, QX; Wang, HS; Zhang, SH; Zhao, Y | 1 |
| Cicha, MZ; Kopp, UC; Yorek, MA | 1 |
| Chiang, H; Hsieh, ST; Hsieh, YL; Tseng, TJ | 1 |
| Li, Z; Liu, H; Liu, Z | 1 |
| Li, J; Wang, DH | 1 |
| Novotny, M; Quaiserová-Mocko, V; Swain, GM; Wang, DH; Wang, Y | 1 |
| Aita, M; Maeda, T; Seo, K | 1 |
| Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Tsuchida, H; Yamashita, M | 1 |
| Sachs, JR; Wang, DH; Xie, C | 1 |
| Andoh, T; Kosaka, M; Kuraishi, Y; Lee, JB; Nakano, T; Tayama, M | 1 |
| Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y | 1 |
| Barrett, E; Xu, F; Xu, J | 1 |
| Choi, JY; Hanrahan, JW; Ianowski, JP; Wine, JJ | 1 |
| Kamei, C; Kuyama, S; Ogawa, M; Yokota, E | 1 |
| Piérard, GE; Quatresooz, P | 1 |
| Aura Kullmann, F; de Groat, WC; Sculptoreanu, A | 1 |
| Dafre, AL; Farina, M; Jacques, AV; Mendes, BG; Meotti, FC; Nascimento, FP; Pizzolatti, MG; Ribas, CM; Rodrigues, AL; Santos, AR; Soldi, C | 1 |
| Bagoly, T; Boronkai, A; Borzsei, R; Brubel, R; Helyes, Z; Horvath, G; Kiss, P; Nemeth, J; Racz, B; Reglodi, D; Tamas, A; Toth, G | 1 |
| Broman, J; Larsson, M | 1 |
| Li, YS; Miyano, K; Nakata, Y; Tang, HB | 1 |
| Li, YS; Morioka, N; Nakata, Y; Ogata, N; Shiba, E; Tang, HB; Zheng, TX | 1 |
| Erin, N; Ulusoy, O | 1 |
| Erin, N; Sarigül, M; Tütüncü, S; Zik, B | 1 |
| Aoki, J; Inoue, M; Ma, L; Ueda, H | 1 |
| Gao, F; Garavito, RM; Sui, D; Wang, DH; Worden, RM | 1 |
| Boudaka, A; Neuhuber, WL; Shiina, T; Shimizu, Y; Takewaki, T; Wörl, J | 1 |
| Li, ZZ; Liu, H; Liu, Z; Wang, H; Wang, L; Yang, X | 1 |
| Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Vale, ML | 1 |
| Adler, JE; Skoff, AM; Zhao, C | 1 |
| Bach, FW; Jensen, TS; Terkelsen, AJ | 1 |
| Carmichael, NM; Charlton, MP; Dostrovsky, JO | 1 |
| Antunes, E; Camargo, EA; Costa, SK; De Nucci, G; Desouza, IA; Mariano, NS; Mello, GC; Optiz-Neto, JB; Resende, JS | 1 |
| Behar, J; Biancani, P; Cao, W; Cheng, L; de la Monte, S; Harnett, KM; Hong, J; Ma, J; Tong, M | 1 |
| Hasan, W; McCarson, KE; Rook, JM | 1 |
| Li, Z; Liu, H; Liu, Z; Wang, H; Yang, X; Zhang, F | 1 |
| Horie, S; Hosoya, T; Kurosawa, E; Matsumoto, K; Murayama, T; Priestley, JV; Tashima, K; Terui, H | 1 |
| Iwata, Y; Komatsu, T; Kuwahata, H; Sakurada, C; Sakurada, S; Sakurada, T; Sanai, K; Sasaki, M; Tsuzuki, M | 1 |
| Bastien, P; Breton, L; Castiel-Higounenc, I; Chevalier, V; Courchay, G; Guéniche, A; Kermici, M; Ovigne, JM | 1 |
| Artim, DE; de Groat, WC; Sculptoreanu, A | 1 |
| Blennerhassett, MG; Liu, H; Lourenssen, S; Miller, DV; Paterson, WG; Wells, RW | 1 |
| Gu, Q; Lee, LY; Lin, YS | 1 |
| Ogawa, H; Takamori, K; Taneda, K; Tengara, S; Tominaga, M | 1 |
| Hamity, MV; Hammond, DL; White, SR | 1 |
| Gao, F; Wang, DH | 1 |
| Ito, K; Miyake, M; Muto, T; Ohshima, M; Sakamoto, T; Takeda, M; Ueda, N | 1 |
| Chen, W; Lao, L; Marvizón, JC; Zhang, G | 1 |
| Fu, YS; Huang, HT; Huang, WH; Liu, SP; Wang, PH | 1 |
| Gong, H; Li, Z; Liu, G; Liu, H; Liu, Z; Yang, X | 1 |
| Boulais, N; Dorange, G; Lebonvallet, N; Misery, L; Pennec, JP; Pereira, U | 1 |
| Gong, H; Li, Z; Liu, G; Liu, Q; Liu, Z; Yang, X | 1 |
| Wang, DH; Xie, C | 1 |
| Xu, F; Xu, J; Zhang, C; Zhuang, J | 1 |
| Boulais, N; Dorange, G; Garcia-Le Gal, C; Gougerot, A; Le Gal, G; Lebonvallet, N; Lefeuvre, L; Misery, L; Pereira, U | 1 |
| Birklein, F; Fuchs, D; Reeh, PW; Sauer, SK | 1 |
| Ballard, CJ; Hurley, JH; Kunkler, PE; Oxford, GS | 1 |
| Choi, JY; Joo, NS; Khansaheb, M; Krouse, M; Wine, JJ; Yang, YM | 1 |
| Daugherty, SL; de Groat, WC; Zhang, X | 1 |
| Appenzeller, M; Bigliardi, P; Buclin, T; Grouzmann, E; Pannatier, A | 1 |
| Davidson, S; Lear, M; MacKenzie, A; Ross, R; Shanley, L | 1 |
| Geraghty, DP; Heng, YJ; Kunde, DA; Saunders, CI | 1 |
| Liu, B; Lü, H; Qiu, Z; Xu, S; Yu, L; Zhao, T | 1 |
| Shindo, M; Yamamoto, O; Yoshida, Y | 1 |
| Guo, Z; Wang, LL; Wu, J; Zhang, RL | 1 |
| Chen, H; Lu, MY; Ren, JY; Song, JX | 1 |
| Komatsu, T; Mizoguchi, H; Sakurada, C; Sakurada, S; Sakurada, T; Sasaki, M; Tsuzuki, M | 1 |
| LeRoy, P | 1 |
| Barbosa, S; Fernández-Blanco, JA; Martínez, V; Sánchez de Medina, F; Vergara, P | 1 |
| Beaudry, H; Dubois, D; Gendron, L | 1 |
| Ang, SF; Bhatia, M; MacAry, PA; Moochhala, SM | 1 |
| Akasaka, Y; Hatta, A; Inoue, H; Sakai, A; Suzuki, H; Takasu, K; Tsukahara, M | 1 |
| Henry, PJ; Mann, TS; Taylor, SJ | 1 |
| Jia, MM; Li, XJ; Li, YS; Liu, M; Tang, HB; Wang, JX | 1 |
| Ditting, T; Fiedler, C; Freisinger, W; Heinlein, S; Neuhuber, W; Reeh, PW; Schmieder, RE; Siegel, K; Small, L; Veelken, R | 1 |
| Wang, HB; Yang, CX; Yao, SL; Zhang, Y; Zhong, JY; Zhou, J | 1 |
| Cao, XH; Gao, X; Li, F; Li, L; Liu, LJ; Liu, ZG; Xu, YP; Yan, XS; Ye, ZY; Zhang, JW; Zhang, Y | 1 |
| Chen, KH; Chen, MJ; Lai, YL | 1 |
| Chien, CT; Lee, HM; Li, PC; Wu, CC | 1 |
| Demir, N; Duymuş, O; Erin, N; Oztürk, S | 1 |
| Ribeiro-da-Silva, A; Saeed, AW | 1 |
| Chen, PX; Guo, HM; Huang, JH; Luo, YL; Zhang, YL; Zhou, WL; Zhu, YX | 1 |
| Guiducci, S; Manetti, M; Matucci-Cerinic, M; Nacci, F; Peruzzi, F; Romano, E; Terenzi, R | 1 |
| Chen, R; Lai, K; Li, J; Li, L; Liu, X; Ma, P; Wu, Y; Yang, X; Yao, H; Ye, X; You, H; Yuan, Y | 1 |
| Antunes, E; Ferreira, J; Hoffmeister, C; Matheus, FC; Mello, GC; Oliveira, SM; Prediger, RD; Rossato, MF; Silva, CR; Trevisan, G | 1 |
| Guo, Z; Meng, XX; Xie, LS; Yang, JH; Zhang, T | 1 |
| Li, PB; Luo, YL; Nie, YC; Su, WW; Wang, S; Zhang, CC; Zhang, KJ; Zheng, YF | 1 |
| Du, JQ; Kong, LH; Liu, XH; Sun, N; Xu, Y; Zhu, JX | 1 |
| Alhelal, MA; Letourneau, R; Palaska, I; Panagiotidou, S; Theoharides, TC | 1 |
| Eddinger, KA; Marino, MJ; Steinauer, JJ; Terashima, T; Xu, Q; Yaksh, TL | 1 |
| Mizoguchi, H; Sakurada, S; Sakurada, T; Sato, T; Takagi, H; Watanabe, C; Yonezawa, A | 1 |
| Ganev, EG; Hiruma-Lima, CA; Martins, DF; Mazzardo-Martins, L; Nishijima, CM; Rocha, LR; Santos, AR | 1 |
| Cooper, BY; Johnson, RD; Petruska, JC; Rau, KK | 1 |
| Chen, CC; Chen, WN | 1 |
| Kushmerick, C; Moraes, ER; Naves, LA | 1 |
| Xu, F; Zang, N; Zhao, L; Zhuang, J | 1 |
| Decorps, J; Fromy, B; Gohin, S; Sigaudo-Roussel, D | 1 |
| Lee, LY; Lin, Y; Xu, F; Zang, N; Zhao, L; Zhuang, J | 1 |
| Hu, R; Li, Z; Liang, J; Pan, X; Sun, W; Wang, X | 1 |
| Cao, X; Chai, S; Chen, Z; Dong, R; Ji, Z; Lai, K; Lv, H; Yue, J; Zhan, J; Zhang, H | 1 |
| Duan, W; Han, L; Huang, JH; Lei, J; Li, X; Ma, J; Ma, Q; Ma, Z; Wang, Z; Wu, E; Wu, Z; Xu, Q; Yu, S; Zhang, L | 1 |
| An, HS; An, S; Chee, A; Chen, EY; Cs-Szabo, G; Lin, H; Qin, L; Shi, P; Tannoury, C; Zhang, Y | 1 |
| Ahlijanian, MK; Graef, JD; Herrington, J; Hoque, N; Kiss, L; Newberry, K; Wang, S | 1 |
| Endo, Y; Nemoto, W; Shima, K; Sugawara, S; Takano-Yamamoto, T; Tan-No, K; Tsuchiya, M | 1 |
| Borbély, É; Helyes, Z; Kemény, Á; Markovics, A; McDougall, JJ; Pintér, E; Quinn, JP; Sándor, K; Szolcsányi, J | 1 |
| Aubdool, AA; Bátai, IZ; Brain, SD; Filotás, D; Hajna, Z; Helyes, Z; Nagy, L; Payrits, M; Pintér, E; Pozsgai, G; Sághy, É; Szőke, É | 1 |
| Azimi, E; Lerner, EA; Pereira, PJS; Reddy, VB; Talbot, S; Woolf, CJ | 1 |
| Hanayama, K; Haruma, K; Hata, J; Manabe, N; Nakato, R; Shimizu, S; Shiotani, A | 1 |
| Clifton, DK; Krull, AA; Larsen, SA; Neal-Perry, G; Steiner, RA | 1 |
| Ishii, K; Ito, H; Kuroki, T; Mori, A; Nakahara, T; Sagawa, T; Sakamoto, K | 1 |
| Bodnár, D; Boros, M; Garab, D; Hartmann, P; Jancsó, G; Járomi, P; Nyíri, S; Sántha, P; Szabó, A | 1 |
| Liu, L; Sun, T; Wang, L; Zhang, L | 1 |
| Amagase, K; Kato, S; Matsumoto, K; Tominaga, M; Tsukahara, T; Utsumi, D | 1 |
| Altamirano-Reyna, F; Arreola-Peralta, LD; Galindo-González, DM; Lacivita, E; Leopoldo, M; Solis-Anguiano, JG; Terrón, JA | 1 |
| Abbasnejad, M; Esmaeili-Mahani, S; Kooshki, R; Mansoori, M; Raoof, M; Soofiabadi, S | 1 |
| Basbaum, AI; Bell, AM; Bennett, DLH; Braz, J; Dickie, AC; Etlin, A; Gutierrez-Mecinas, M; Iwagaki, N; Kelly, R; Lyon, H; Polgár, E; Riddell, JS; Todd, AJ; Turnbull, K; Watanabe, M; West, SJ | 1 |
| Chen, CC; Han, DS; Lee, CH; Shieh, YD | 1 |
| Bäumer, W; Fukuyama, T; Ganchingco, JRC; Yoder, JA | 1 |
| Dong, L; Fei, X; Liu, D; Yuan, J; Zhang, C; Zhou, Y; Zhu, Y; Zhu, Z | 1 |
| Hanayama, K; Haruma, K; Hata, J; Kusunoki, H; Manabe, N; Nakato, R | 1 |
| Claus, I; Dziewas, R; Egidi, P; Gminski, R; Gross, J; Jungheim, M; Kampe, I; Labeit, B; Lenze, F; Muhle, P; Ruck, T; Suntrup-Krueger, S; Warnecke, T | 1 |
| Kim, Y; Lyall, V; Rhyu, MR | 1 |
| De Luca, R; Haas, HL; Kernder, A; Mazur, K; Sergeeva, OA | 1 |
| Doi, M; Imado, E; Irifune, M; Kanematsu, T; Kochi, T; Morioka, N; Mukai, A; Nakamura, Y; Nakata, Y; Onizuka, C; Oue, K; Sakai, N; Shimizu, Y; Yoshida, M | 1 |
| Baek, EJ; Kim, KH; Kim, KJ; Oh, DY; Park, EJ; Shin, SM | 1 |
| Bellemere, G; Bocciarelli, C; Bredif, S; Cordel, N; Fluhr, J; Hu, W; Le Gall-Ianotto, C; Lebonvallet, N; Leschiera, R; Marcorelles, P; Misery, L; Talagas, M | 1 |
44 review(s) available for capsaicin and substance p
| Article | Year |
|---|---|
Neurogenic inflammation and the oral mucosa.
Topics: Capsaicin; Humans; Inflammation; Mouth Mucosa; Neurons, Afferent; Sensory Receptor Cells; Substance P; Vasodilation | 1992 |
Substance P theory: a unique focus on the painful and painless phenomena of cluster headache.
Topics: Capsaicin; Cluster Headache; Female; Humans; Iris; Male; Models, Biological; Nasal Mucosa; Salivary Glands; Substance P; Transcutaneous Electric Nerve Stimulation; Vascular Headaches | 1990 |
Substance P afferents regulate ACTH-corticosterone release.
Topics: Adrenocorticotropic Hormone; Afferent Pathways; Animals; Capsaicin; Corticosterone; Hypothalamo-Hypophyseal System; Neurons; Pituitary-Adrenal System; Rats; Reflex; Stress, Physiological; Substance P | 1991 |
The complexity and diversity of synaptic transmission in the prevertebral sympathetic ganglia.
Topics: Animals; Autonomic Fibers, Preganglionic; Bombesin; Capsaicin; Cell Count; Enkephalins; Ganglia, Sympathetic; Guinea Pigs; Nerve Tissue Proteins; Neural Conduction; Neural Inhibition; Neuropeptide Y; Rabbits; Rana catesbeiana; Reflex; Somatostatin; Substance P; Synapses; Synaptic Transmission; Vasoactive Intestinal Peptide | 1985 |
Search for a physiological role of substance P in gastrointestinal motility.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Drug Resistance; Endorphins; Gastrointestinal Motility; Humans; Ileum; Muscle Contraction; Nerve Fibers; Neural Inhibition; Neurons; Peristalsis; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Somatostatin; Splanchnic Nerves; Structure-Activity Relationship; Substance P; Vagus Nerve | 1985 |
The role of neuropeptides in the regulation of the micturition reflex.
Topics: Animals; Biogenic Amines; Capsaicin; Endorphins; Nerve Tissue Proteins; Neurons, Afferent; Neurons, Efferent; Pelvis; Reflex; Spinal Cord; Substance P; Synaptic Transmission; Tachykinins; Urinary Bladder; Urinary Tract; Urination; Vasoactive Intestinal Peptide | 1986 |
Neuropeptides and the pathogenesis of allergy.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Hypersensitivity; Inflammation; Mast Cells; Neurokinin A; Neuropeptides; Peripheral Nerves; Substance P | 1987 |
Peptides and neurogenic inflammation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Inflammation; Nervous System; Neuropeptides; Substance P | 1987 |
[Neuroautonomic mechanisms and neuropeptides in bronchial asthma].
Topics: Animals; Asthma; Autonomic Nervous System; Capsaicin; Humans; Neuropeptides; Substance P; Vasoactive Intestinal Peptide | 1988 |
Capsaicin in dermatologic disease.
Topics: Capsaicin; Humans; Middle Aged; Neuralgia; Pruritus; Skin Diseases; Substance P | 1988 |
Neurophysiological effects of capsaicin.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Capsaicin; Cardiovascular System; Cell Membrane; Digestive System; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Nerve Fibers; Nervous System; Nociceptors; Pain; Rats; Receptors, Opioid; Substance P | 1984 |
Capsaicin and central control of thermoregulation.
Topics: Animals; Body Temperature; Body Temperature Regulation; Capsaicin; Drug Tolerance; Fever; Hemodynamics; Humans; Hypothalamus; Hypothalamus, Anterior; Neurons; Neurons, Afferent; Neurotransmitter Agents; Respiration; Substance P | 1984 |
The role of substance P in sensory transmission and pain perception.
Topics: Animals; Capsaicin; Ganglia, Spinal; Membrane Potentials; Neurons, Afferent; Neurotransmitter Agents; Pain; Substance P | 1981 |
Ocular neuropeptides.
Topics: Animals; Anterior Chamber; Bradykinin; Capsaicin; Enkephalins; Eye; Humans; Nerve Fibers; Neurotensin; Ocular Physiological Phenomena; Peptides; Pupil; Retina; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1982 |
Neuropeptides in sensory neurons.
Topics: Angiotensin II; Animals; Bombesin; Capsaicin; Cholecystokinin; Gastrointestinal Hormones; Guinea Pigs; Immunoassay; Neurons, Afferent; Peptides; Radioimmunoassay; Somatostatin; Spinal Cord; Substance P; Vasoactive Intestinal Peptide | 1982 |
Role of substance P as a sensory transmitter in spinal cord and sympathetic ganglia.
Topics: Action Potentials; Animals; Calcium; Capsaicin; Electric Stimulation; Electrophysiology; Enkephalins; Ganglia, Sympathetic; Motor Neurons; Neurons, Afferent; Rats; Spinal Cord; Substance P; Synapses; Synaptic Transmission | 1982 |
Substance P in nociceptive sensory neurons.
Topics: 5,6-Dihydroxytryptamine; Action Potentials; Afferent Pathways; Animals; Capsaicin; Electric Stimulation; Enkephalins; Neurons; Neurons, Afferent; Nociceptors; Potassium; Raphe Nuclei; Receptors, Opioid; Serotonin; Spinal Cord; Substance P | 1982 |
If substance P fails to fulfil the criteria as a neurotransmitter in somatosensory afferents, what might be its function?
Topics: Action Potentials; Animals; Biological Transport; Capsaicin; Electric Stimulation; Hot Temperature; Models, Biological; Nerve Crush; Neurons, Afferent; Pain; Peripheral Nerve Injuries; Peripheral Nerves; Sensory Receptor Cells; Spinal Cord; Substance P; Synaptic Transmission | 1982 |
Substance P in peripheral sensory processes.
Topics: Animals; Axonal Transport; Axons; Capsaicin; Evoked Potentials; Femoral Nerve; Histamine; Ligation; Nerve Endings; Neurons, Afferent; Peripheral Nerves; Sciatic Nerve; Somatostatin; Substance P; Vasodilation | 1982 |
Localization of substance P in neuronal pathways.
Topics: Animals; Brain; Brain Stem; Capsaicin; Diencephalon; Enkephalins; gamma-Aminobutyric Acid; Histocytochemistry; Mesencephalon; Microscopy, Electron; Neural Pathways; Neurons; Neurons, Afferent; Spinal Cord; Substance P; Substantia Nigra; Synapses; Telencephalon; Tissue Distribution | 1982 |
Capsaicin--a literature survey.
Topics: Analgesia; Animals; Blood Pressure; Body Temperature Regulation; Capsaicin; Cardiovascular System; Chemical Phenomena; Chemistry; Colon; Dose-Response Relationship, Drug; Drug Tolerance; Fatty Acids, Unsaturated; Heart Rate; Histamine; Intestine, Small; Liver; Muscle, Smooth, Vascular; Myocardial Contraction; Pain; Phagocytosis; Respiratory System; Stomach Ulcer; Substance P; Vagus Nerve | 1982 |
Capsaicin and sensory neurones--a review.
Topics: Animals; Axonal Transport; Axons; Capsaicin; Cholecystokinin; Edema; Fatty Acids, Unsaturated; Ganglia, Spinal; Nerve Degeneration; Nerve Fibers; Neurons, Afferent; Pain; Rats; Reflex; Sensation; Substance P | 1983 |
Mediators of vasodilatation in the skin.
Topics: Axons; Capsaicin; Dendrites; Histamine Release; Humans; Neurons, Afferent; Nociceptors; Reflex; Skin; Substance P; Vasodilation | 1983 |
Neuropeptides contained in peripheral cardiovascular nerves.
Topics: Animals; Capsaicin; Cardiovascular System; Enkephalins; Gastrin-Releasing Peptide; Humans; Nerve Tissue Proteins; Neuropeptide Y; Peptides; Peripheral Nerves; Substance P; Vasoactive Intestinal Peptide | 1984 |
Eye of newt and toe of frog: substance P and the charmed pot of neuropeptides.
Topics: Adrenal Medulla; Animals; Anura; Capsaicin; Carcinoid Tumor; Ganglia, Sympathetic; Humans; Nerve Tissue Proteins; Neurons, Efferent; Neurotransmitter Agents; Ocular Physiological Phenomena; Substance P | 1984 |
The origin and possible significance of substance P immunoreactive networks in the prevertebral ganglia and related structures in the guinea-pig.
Topics: Animals; Antibodies, Monoclonal; Capsaicin; Ganglia, Spinal; Ganglia, Sympathetic; Guinea Pigs; Intestine, Small; Male; Nervous System Physiological Phenomena; Neurons, Afferent; Spinal Cord; Substance P | 1984 |
Topical capsaicin-pharmacology and potential role in the treatment of temporomandibular pain.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Disease; Facial Pain; Humans; Nerve Fibers; Substance P; Temporomandibular Joint Disorders | 1994 |
Protons: small stimulants of capsaicin-sensitive sensory nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electrophysiology; Guinea Pigs; Neurokinin A; Neurons, Afferent; Protons; Rats; Ruthenium Red; Substance P | 1994 |
[Capsaicin for arthritic pain].
Topics: Analgesics; Animals; Arthritis; Arthritis, Experimental; Capsaicin; Humans; Pain; Substance P | 1996 |
Neurogenic inflammation. A model for studying efferent actions of sensory nerves.
Topics: Afferent Pathways; Animals; Capillary Leak Syndrome; Capsaicin; Carotid Body; Efferent Pathways; Endothelium, Vascular; Guinea Pigs; Inflammation; Mycoplasma Infections; Neovascularization, Pathologic; Neurons, Afferent; Rats; Receptors, Neurokinin-1; Respiratory System; Respiratory Tract Diseases; Respiratory Tract Infections; Substance P; Venules | 1996 |
Neurogenic acceleration of osteoarthritis.
Topics: Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Electrophysiology; Humans; Nervous System; Neuropeptides; Osteoarthritis; Proprioception; Substance P | 1998 |
Efferent functions of C-fiber nociceptors.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Efferent Pathways; Fibromyalgia; Humans; Inflammation; Nerve Fibers; Neurokinin A; Nociceptors; Skin; Substance P; Swine | 1998 |
[Biochemistry of pain].
Topics: Afferent Pathways; Animals; Capsaicin; Glutamic Acid; Humans; Narcotics; Nerve Growth Factors; Neurons, Afferent; Pain; Peripheral Nerves; Prostaglandins; Spinal Cord; Substance P | 1999 |
Role of neurotransmitters in sensitization of pain responses.
Topics: Animals; Biphenyl Compounds; Capsaicin; Excitatory Amino Acid Agonists; Haplorhini; Hot Temperature; Humans; Hyperalgesia; Injections, Intradermal; Long-Term Potentiation; Mechanoreceptors; Microdialysis; Models, Animal; Models, Neurological; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Pain; Phosphorylation; Posterior Horn Cells; Protein Processing, Post-Translational; Rats; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Signal Transduction; Spinothalamic Tracts; Substance P | 2001 |
[Neurogenic inflammation. I. Basic mechanisms, physiology and pharmacology].
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Inflammation; Nerve Fibers; Neuritis; Neurons, Afferent; Substance P | 2002 |
[Progress in the field of pulmonary medicine in the last 100 years: Medical history of aspiration pneumonitis].
Topics: Amantadine; Angiotensin-Converting Enzyme Inhibitors; Capsaicin; Cerebrovascular Disorders; Dopamine; History, 20th Century; Humans; Pneumonia, Aspiration; Substance P | 2002 |
Innervation of immune cells: evidence for neuroimmunomodulation in the liver.
Topics: Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Capsaicin; Hepatitis, Animal; Kupffer Cells; Liver; Lymphocytes; Mice; Models, Immunological; Receptors, Neurotransmitter; Substance P | 2004 |
Idiopathic pulmonary fibrosis: a nervous cough?
Topics: Adrenal Cortex Hormones; Capsaicin; Cough; Humans; Nerve Growth Factors; Pulmonary Fibrosis; Substance P | 2004 |
The vanilloid receptor and hypertension.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Hypertension; Ion Channels; Neurons, Afferent; Receptors, Drug; Renin-Angiotensin System; Sodium Chloride, Dietary; Substance P; TRPV Cation Channels | 2005 |
Preventive strategies for aspiration pneumonia in elderly disabled persons.
Topics: Amantadine; Angiotensin-Converting Enzyme Inhibitors; BCG Vaccine; Capsaicin; Cilostazol; Deglutition; Disabled Persons; Dopamine; Folic Acid; Glossopharyngeal Nerve; Hand Disinfection; Humans; Influenza Vaccines; Pneumonia, Aspiration; Pneumonia, Bacterial; Posture; Substance P; Tetrazoles | 2005 |
TRP channels as novel players in the pathogenesis and therapy of itch.
Topics: Animals; Cannabinoids; Capsaicin; Central Nervous System; Histamine; Humans; Inflammation Mediators; Nerve Growth Factors; Neurons; Neurons, Afferent; Neuropeptides; Pain; Pruritus; Spinal Cord; Substance P; Temperature; Transient Receptor Potential Channels; TRPV Cation Channels | 2007 |
Effect of smoking on cough reflex sensitivity: basic and preclinical studies.
Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cough; Guinea Pigs; Humans; Models, Animal; Nerve Fibers, Unmyelinated; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Reflex; Sensory System Agents; Smoking; Substance P | 2010 |
Diagnosis and treatments for oropharyngeal dysphagia: effects of capsaicin evaluated by newly developed ultrasonographic method.
Topics: Capsaicin; Deglutition Disorders; Gastrointestinal Motility; Humans; Substance P; TRPV Cation Channels; Ultrasonography, Doppler | 2020 |
Interactions between Chemesthesis and Taste: Role of TRPA1 and TRPV1.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cations; Humans; Mice; Neurons; Plant Extracts; Polymorphism, Single Nucleotide; Rats; Republic of Korea; Sensory Receptor Cells; Spices; Substance P; Taste; Taste Buds; Trigeminal Nerve; TRPA1 Cation Channel; TRPV Cation Channels | 2021 |
15 trial(s) available for capsaicin and substance p
| Article | Year |
|---|---|
Treatment of aquagenic pruritus with topical capsaicin cream.
Topics: Administration, Topical; Capsaicin; Double-Blind Method; Female; Fluorescent Antibody Technique; Humans; Male; Nerve Fibers; Neuropeptides; Pruritus; Skin; Substance P; Water | 1994 |
A double-blind evaluation of topical capsaicin in pruritic psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Capsaicin; Double-Blind Method; Female; Humans; Male; Middle Aged; Pruritus; Psoriasis; Substance P | 1993 |
Resolution of ACE inhibitor cough: changes in subjective cough and responses to inhaled capsaicin, intradermal bradykinin and substance-P.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Capsaicin; Cough; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Substance P | 1995 |
Uremic pruritus: roles of parathyroid hormone and substance P.
Topics: Calcium; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Parathyroid Hormone; Phosphates; Pruritus; Renal Dialysis; Substance P | 1997 |
The effect of topical capsaicin on substance P immunoreactivity: a clinical trial and immunohistochemical analysis.
Topics: Administration, Topical; Capsaicin; Dose-Response Relationship, Drug; Double-Blind Method; Fluorescent Antibody Technique, Indirect; Humans; Prurigo; Substance P; Treatment Outcome | 1997 |
No release of histamine and substance P in capsaicin-induced neurogenic inflammation in intact human skin in vivo: a microdialysis study.
Topics: Administration, Topical; Adult; Capsaicin; Dose-Response Relationship, Drug; Histamine Release; Humans; Injections, Intradermal; Male; Microdialysis; Middle Aged; Neuritis; Skin; Substance P | 1997 |
Intravesical capsaicin in patients with detrusor hyper-reflexia--a placebo-controlled cross-over study.
Topics: Administration, Intravesical; Anesthetics, Local; Capsaicin; Cross-Over Studies; Female; Humans; Lidocaine; Male; Middle Aged; Premedication; Reflex, Abnormal; Spinal Cord Diseases; Substance P; Time Factors; Urinary Bladder; Urinary Bladder, Neurogenic; Urodynamics | 1999 |
Treatment of prurigo nodularis with topical capsaicin.
Topics: Administration, Topical; Adult; Aged; Biopsy; Capsaicin; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Prurigo; Pruritus; Substance P; Treatment Outcome | 2001 |
The ACE gene polymorphism and cough threshold for capsaicin after cilazapril usage.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bronchial Provocation Tests; Capsaicin; Cilazapril; Cough; Cross-Over Studies; Double-Blind Method; Female; Genetic Predisposition to Disease; Genotype; Humans; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Skin Tests; Substance P | 2001 |
The effects of capsaicin topical therapy in dogs with atopic dermatitis: a randomized, double-blinded, placebo-controlled, cross-over clinical trial.
Topics: Administration, Cutaneous; Animals; Capsaicin; Cross-Over Studies; Dermatitis, Atopic; Dog Diseases; Dogs; Double-Blind Method; Female; Male; Pruritus; Substance P; Treatment Outcome | 2002 |
Immunohistochemical clues at aging of the skin microvascular unit.
Topics: Adult; Aged; Aging; Antigens, CD34; Capsaicin; Dendritic Cells; Factor XIIIa; Humans; Immunohistochemistry; Male; Microvessels; Sensory System Agents; Skin; Substance P; Thrombomodulin | 2009 |
Bifidobacterium longum lysate, a new ingredient for reactive skin.
Topics: Administration, Topical; Adult; Bifidobacterium; Biopsy; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Dermatitis; Double-Blind Method; Emollients; Female; Humans; Middle Aged; Pilot Projects; Probiotics; Sensory Receptor Cells; Sensory System Agents; Skin; Skin Diseases; Substance P; Treatment Outcome; Tumor Necrosis Factor-alpha | 2010 |
Substance P-induced skin inflammation is not modulated by a single dose of sitagliptin in human volunteers.
Topics: Capsaicin; Carbonated Beverages; Cross-Over Studies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Eruptions; Edema; Erythema; Humans; Injections, Intradermal; Male; Pain; Pyrazines; Sitagliptin Phosphate; Skin; Substance P; Triazoles; Vasodilation | 2011 |
Olopatadine hydrochloride inhibits capsaicin-induced flare response in humans.
Topics: Administration, Topical; Adult; Capsaicin; Dibenzoxepins; Erythema; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Olopatadine Hydrochloride; Sensory Receptor Cells; Skin; Substance P; Treatment Outcome; Young Adult | 2011 |
Effects of Capsaicin on Older Patients with Oropharyngeal Dysphagia: A Double-Blind, Placebo-Controlled, Crossover Study.
Topics: Age Factors; Aged; Aged, 80 and over; Capsaicin; Cross-Over Studies; Deglutition; Deglutition Disorders; Dietary Supplements; Double-Blind Method; Esophagus; Female; Humans; Male; Middle Aged; Standard of Care; Substance P; Time Factors; TRPV Cation Channels; Ultrasonography, Doppler | 2017 |
1230 other study(ies) available for capsaicin and substance p
| Article | Year |
|---|---|
Pharmacologic actions of capsaicin: apparent involvement of substance P and serotonin.
Topics: Animals; Blood Pressure; Body Temperature Regulation; Capsaicin; Fatty Acids, Unsaturated; Heart; Intestines; Neural Conduction; Neurons; Neurotransmitter Agents; Rats; Respiration; Sensation; Serotonin; Structure-Activity Relationship; Substance P | 1979 |
Longitudinal contraction of isolated guinea-pig ileum induced by rapid cooling.
Topics: Animals; Capsaicin; Cold Temperature; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Serotonin; Substance P; Tachyphylaxis; Temperature | 1979 |
Capsaicin-induced depletion of substance P from primary sensory neurones.
Topics: Acid Phosphatase; Afferent Pathways; Animals; Capsaicin; Fatty Acids, Unsaturated; Fluorescent Antibody Technique; Glutamate Decarboxylase; Male; Rats; Receptors, Opioid; Spinal Cord; Substance P; Substantia Gelatinosa | 1978 |
Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Hot Temperature; Injections, Spinal; Movement; Nociceptors; Pain; Rats; Spinal Cord; Substance P; Synaptic Transmission | 1979 |
Capsaicin-evoked release of substance P from primary sensory neurons.
Topics: Animals; Calcium; Capsaicin; Evoked Potentials; Fatty Acids, Unsaturated; Motor Neurons; Nociceptors; Radioimmunoassay; Rats; Spinal Cord; Substance P | 1979 |
Substance P release from spinal cord slices by capsaicin.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Female; Hypothalamus; In Vitro Techniques; Potassium; Rats; Spinal Cord; Substance P; Substantia Nigra; Time Factors | 1979 |
Tachykinin systems in the spinal cord and basal ganglia: influence of neonatal capsaicin treatment or dopaminergic intervention on levels of peptides, substance P-encoding mRNAs, and substance P receptor mRNA.
Topics: Animals; Animals, Newborn; Basal Ganglia; Blotting, Northern; Capsaicin; Chromatography, High Pressure Liquid; Dopamine Agents; Dynorphins; Endorphins; Female; Haloperidol; Injections, Subcutaneous; Neurokinin A; Neurons; Neurotoxins; Pregnancy; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurotransmitter; RNA, Messenger; Spinal Cord; Substance P; Tachykinins | 1992 |
Sensory neuropeptide interactions in the production of plasma extravasation in the rat.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Galanin; Male; Neurons, Afferent; Neuropeptides; Peptides; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P | 1992 |
Capsaicin prevents the adrenocorticotropin-induced improvement of cardiovascular function and survival in hemorrhage-shocked rats.
Topics: Adrenocorticotropic Hormone; Afferent Pathways; Animals; Capsaicin; Cosyntropin; Endorphins; Female; Hemodynamics; Male; Neurons, Afferent; Rats; Rats, Wistar; Recombinant Proteins; Shock, Hemorrhagic; Substance P; Survival Rate | 1992 |
Adenosine inhibits action potential-dependent release of calcitonin gene-related peptide- and substance P-like immunoreactivities from primary afferents in rat spinal cord.
Topics: Action Potentials; Adenosine; Animals; Baclofen; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Wistar; Spinal Cord; Substance P; Tetrodotoxin | 1992 |
Effect of capsaicin and resiniferatoxin on peptidergic neurons in cultured dorsal root ganglion.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Cell Differentiation; Culture Techniques; Diterpenes; Ganglia, Spinal; Immunohistochemistry; Neurons, Afferent; Substance P | 1992 |
Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs.
Topics: Administration, Intranasal; Administration, Topical; Animals; Atropine; Benzenesulfonates; Capsaicin; Chromones; Coloring Agents; Diphenhydramine; Exudates and Transudates; Guinea Pigs; Histamine; Histamine Release; Injections, Subcutaneous; Lidocaine; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Substance P | 1992 |
Capsaicin releases calcitonin gene-related peptide from the human iris and ciliary body in vitro.
Topics: Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; Ciliary Body; Female; Humans; In Vitro Techniques; Iris; Male; Middle Aged; Radioimmunoassay; Substance P | 1992 |
UK-14,304, R(-)-alpha-methyl-histamine and SMS 201-995 block plasma protein leakage within dura mater by prejunctional mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Capillary Permeability; Capsaicin; Dura Mater; Electric Stimulation; Guinea Pigs; Histamine Agonists; Injections, Intravenous; Male; Methylhistamines; Octreotide; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Receptors, Histamine H3; Receptors, Somatostatin; Substance P | 1992 |
The capsaicin test in mice for evaluating tachykinin antagonists in the spinal cord.
Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Pain Measurement; Spinal Cord; Substance P; Tachykinins | 1992 |
Release and depletion of substance P by capsaicin in substantia gelatinosa studied with the antibody microprobe technique and immunohistochemistry.
Topics: Afferent Pathways; Animals; Antibodies; Capsaicin; Cats; Immunohistochemistry; Microelectrodes; Nerve Endings; Substance P; Substantia Gelatinosa; Video Recording | 1992 |
Changes in airway reactivity to exogenous and endogenous acetylcholine and substance P after anaphylactic bronchoconstriction in anaesthetized guinea-pigs.
Topics: Acetylcholine; Anaphylaxis; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Substance P; Vagus Nerve | 1992 |
Capsaicin-like effect of (6)-shogaol on substance P-containing primary afferents of rats: a possible mechanism of its analgesic action.
Topics: Analgesics; Animals; Capsaicin; Catechols; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1992 |
Neonatal capsaicin treatment prevents the development of the thermal hyperalgesia produced in a model of neuropathic pain in the rat.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Hot Temperature; Male; Nervous System Diseases; Pain; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1992 |
Intrathecal oxymetazoline does not produce neurotoxicity in the spinal cord of the rat.
Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Gait; Immunohistochemistry; Injections, Spinal; Male; Motor Activity; Neurotoxins; Oxymetazoline; Pain; Posture; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1992 |
Substance P as a potent stimulator of sneeze responses in experimental allergic rhinitis of guinea pigs.
Topics: Animals; Ascaris; Capsaicin; Guinea Pigs; Histamine; Nasal Mucosa; Rhinitis, Allergic, Seasonal; Sneezing; Substance P | 1992 |
[The role of substance P in the modulation of myotension in paralyzed limbs after spinal transsection on rats].
Topics: Animals; Capsaicin; Electromyography; Female; Injections, Spinal; Muscle Hypertonia; Muscle Tonus; Paraplegia; Rats; Rats, Wistar; Spinal Cord Injuries; Substance P | 1992 |
Capsaicin desensitization inhibits cigarette smoke-induced increase in cytoplasmic motility of alveolar macrophages in guinea pigs.
Topics: Acetylcholine; Acrolein; Animals; Capsaicin; Cytoplasm; Dose-Response Relationship, Drug; Ferric Compounds; Guinea Pigs; Macrophages, Alveolar; Nicotiana; Nicotine; Plants, Toxic; Smoke; Substance P | 1992 |
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation | 1992 |
Cellular-neural-cellular pathways mediating the response of tracheal ciliary beat frequency (CBFt) to inhaled capsaicin.
Topics: Animals; Autonomic Nervous System; Capsaicin; Cilia; Dogs; In Vitro Techniques; Neural Pathways; Neurons, Afferent; Substance P; Trachea | 1992 |
Inhibition of neurogenic plasma exudation in guinea-pig airways by CP-96,345, a new non-peptide NK1 receptor antagonist.
Topics: Animals; Biphenyl Compounds; Capsaicin; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Male; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Vagus Nerve | 1992 |
Differential inhibitory effects of opioids on cigarette smoke, capsaicin and electrically-induced goblet cell secretion in guinea-pig trachea.
Topics: Animals; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methacholine Compounds; Morphine; Narcotics; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Smoking; Substance P; Trachea; Vagus Nerve | 1992 |
Substance P provokes cutaneous erythema and edema through a histamine-independent pathway.
Topics: Adult; Capsaicin; Edema; Erythema; Female; Histamine; Humans; Hydroxyzine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Substance P | 1992 |
Plasticity of the serotonergic innervation of the dorsal horn of the rat spinal cord following neonatal capsaicin treatment.
Topics: Aging; Animals; Animals, Newborn; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Immunohistochemistry; Microscopy, Electron; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P | 1992 |
Neonatal capsaicin treatment attenuates spinal Fos activation and dynorphin gene expression following peripheral tissue inflammation and hyperalgesia.
Topics: Animals; Animals, Newborn; Capsaicin; Dynorphins; Enkephalins; Female; Foot Diseases; Gene Expression; Hyperalgesia; Inflammation; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1992 |
Involvement of dynorphin A and not substance P in the spinal antianalgesic action of capsaicin against morphine-induced antinociception in mice.
Topics: Analgesia; Animals; Capsaicin; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Spine; Substance P | 1992 |
Increased levels of substance P in the myenteric plexus of Trichinella-infected rats.
Topics: Animals; Capsaicin; Carbachol; Male; Muscle Contraction; Myenteric Plexus; Peroxidase; Rats; Rats, Inbred Strains; Substance P; Trichinellosis | 1992 |
Effect of neuropeptides released from sensory nerves on blood flow in the rat airway microcirculation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Male; Microcirculation; Microspheres; Neurons, Afferent; Neuropeptides; Rats; Rats, Inbred F344; Regional Blood Flow; Respiratory System; Substance P | 1992 |
Release of substance P-like immunoreactive material from the stomach of the rainbow trout.
Topics: Animals; Capsaicin; Gastric Mucosa; Neurons, Afferent; Regional Blood Flow; Rest; Stomach; Substance P; Trout | 1992 |
Involvement of capsaicin-sensitive neurones in the haemodynamic effects of exogenous vasoactive peptides: studies in conscious, adult Long Evans rats treated neonatally with capsaicin.
Topics: Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cholecystokinin; Hemodynamics; Neurons; Neuropeptides; Rats; Substance P; Vasoconstrictor Agents; Vasodilator Agents | 1992 |
Effect of endothelium on the actions of sympathetic and sensory nerves in the perfused rat mesentery.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Endothelium, Vascular; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Neurons, Afferent; Perfusion; Rats; Rats, Inbred Strains; Substance P; Sympathetic Nervous System; Vasoconstriction | 1992 |
Re-innervation of submucosal arterioles by myenteric neurones following extrinsic denervation.
Topics: Animals; Arterioles; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Male; Muscle Denervation; Muscle, Smooth, Vascular; Myenteric Plexus; Neurons; Substance P; Vasoactive Intestinal Peptide; Vasodilation | 1992 |
Development of an antiserum to the midportion of substance P: applications for biochemical and anatomical studies of substance P-related peptide species in CNS tissues.
Topics: Animals; Capsaicin; Central Nervous System; Chromatography, High Pressure Liquid; Female; Ganglia; Immune Sera; Immunohistochemistry; Neuropeptides; Rabbits; Radioimmunoassay; Sensation; Substance P | 1992 |
[Effects of substance P in rat spinal cord on the humoral immune response to SRBC].
Topics: Animals; Antibody Formation; Capsaicin; Catecholamines; Female; Hemolytic Plaque Technique; Immune Sera; Male; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1992 |
Weight loss induced by gastric implant in rats. Effects of capsaicin sensory denervation.
Topics: Animals; Capsaicin; Female; Gastric Balloon; Nerve Degeneration; Neurons, Afferent; Rats; Rats, Inbred Strains; Satiation; Silicones; Stomach; Substance P; Vagus Nerve; Weight Loss | 1992 |
Substance P-immunoreactive sensory axons in the rat respiratory tract: a quantitative study of their distribution and role in neurogenic inflammation.
Topics: Animals; Arterioles; Axons; Bronchi; Capsaicin; Ganglia; Histocytochemistry; Inflammation; Male; Muscle, Smooth, Vascular; Neurons, Afferent; Rats; Rats, Inbred F344; Respiratory System; Substance P; Trachea; Vagotomy; Venules | 1992 |
Sensory nerves in the airways as a target for drug development.
Topics: Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Azepines; Bronchi; Bronchoconstriction; Capsaicin; Drug Design; Electric Stimulation; Guinea Pigs; Indomethacin; Male; Neurons, Afferent; Oligopeptides; Receptors, Opioid; Receptors, Opioid, mu; Substance P; Temperature | 1992 |
Effects of FK224, a novel compound NK1 and NK2 receptor antagonist, on airway constriction and airway edema induced by neurokinins and sensory nerve stimulation in guinea pigs.
Topics: Animals; Bronchoconstriction; Capsaicin; Constriction, Pathologic; Edema; Guinea Pigs; Histamine Antagonists; Injections, Intravenous; Male; Peptides, Cyclic; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Trachea | 1992 |
Pretreatment with aerosolized capsaicin potentiates histamine-induced bronchoconstriction in guinea pigs.
Topics: Aerosols; Animals; Bronchoconstriction; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; Male; Substance P; Trachea | 1992 |
Plasticity in expression of calcitonin gene-related peptide and substance P immunoreactivity in ganglia and fibres following guanethidine and/or capsaicin denervation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Arteries; Dura Mater; Ganglia; Gene Expression; Guanethidine; Immunohistochemistry; Nerve Degeneration; Nerve Fibers; Neuronal Plasticity; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Sympathectomy, Chemical; Sympathetic Nervous System | 1992 |
Neonatal capsaicin-treatment in mice: effects on pancreatic peptidergic nerves and 2-deoxy-D-glucose-induced insulin and glucagon secretion.
Topics: Animals; Animals, Newborn; Blood Glucose; Calcitonin Gene-Related Peptide; Capsaicin; Deoxyglucose; Female; Galanin; Glucagon; Immunohistochemistry; Insulin; Insulin Secretion; Mice; Neuropeptides; Pancreas; Peptides; Substance P | 1992 |
Distribution of neurokinin B in rat spinal cord and peripheral tissues: comparison with neurokinin A and substance P and effects of neonatal capsaicin treatment.
Topics: Animals; Animals, Newborn; Capsaicin; Ganglia, Spinal; Guinea Pigs; Male; Neurokinin A; Neurokinin B; Organ Specificity; Radioimmunoassay; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Substance P | 1992 |
The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1- azabicyclo[2.2.2]-octan-3-amine as a novel, nonpeptide substance P antagonisst.
Topics: Amino Acid Sequence; Animals; Biphenyl Compounds; Capsaicin; Cells, Cultured; Cerebral Cortex; Cricetinae; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Humans; Male; Molecular Sequence Data; Rats; Rats, Inbred Strains; Salivation; Structure-Activity Relationship; Substance P | 1992 |
Involvement of CGRP in the control of acetylcholine-induced endothelium-dependent vascular relaxation.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Endothelium, Vascular; Immunohistochemistry; In Vitro Techniques; Mesenteric Arteries; Methoxamine; Muscle, Smooth, Vascular; Neuropeptide Y; Nitric Oxide; Rats; Rats, Inbred Strains; Substance P; Vasodilation | 1992 |
Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Edema; In Vitro Techniques; Inflammation; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1992 |
Substance P in the regulation of mucociliary transport in the frog palate.
Topics: Acetylcholine; Animals; Capsaicin; Electric Stimulation; Mucociliary Clearance; Palate; Rana pipiens; Substance P | 1992 |
Characterization of the receptor mediating relaxation to substance P in canine middle cerebral artery: no evidence for involvement of substance P in neurogenically mediated relaxation.
Topics: Animals; Arginine; Capsaicin; Cerebral Arteries; Dogs; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; omega-N-Methylarginine; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synaptic Transmission; Vasodilation | 1992 |
Bronchodilatation by tachykinins and capsaicin in the mouse main bronchus.
Topics: Animals; Bronchoconstriction; Capsaicin; Carbachol; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Mice; Neuropeptides; Substance P; Tachykinins | 1992 |
Effect of resiniferatoxin on the isolated rabbit iris sphincter muscle: comparison with capsaicin and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Captopril; Diterpenes; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Rabbits; Substance P; Tachykinins; Tachyphylaxis; Thiorphan | 1992 |
Lithium inhibits substance P and vasoactive intestinal peptide-induced relaxations on isolated porcine ophthalmic artery.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; In Vitro Techniques; Lithium; Muscle Relaxation; Muscle, Smooth, Vascular; Ophthalmic Artery; Substance P; Swine; Vasoactive Intestinal Peptide | 1992 |
Effect of capsaicin as a neuropeptide-releasing substance on sneezing reflex in a type I allergic animal model.
Topics: Animals; Capsaicin; Guinea Pigs; Histamine; Hypersensitivity; Male; Nasal Mucosa; Neuropeptides; Reflex; Sneezing; Substance P | 1992 |
Effects of the tripeptide substance P antagonist, FR113680, on airway constriction and airway edema induced by neurokinins in guinea-pigs.
Topics: Amino Acid Sequence; Animals; Bronchi; Bronchoconstriction; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; Kinins; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Oligopeptides; Pulmonary Edema; Substance P; Trachea | 1992 |
Inhibitory actions of prostaglandin E1 on neurogenic plasma extravasation in rat airways.
Topics: Alprostadil; Animals; Blood Proteins; Bronchi; Capsaicin; Electric Stimulation; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Neuritis; Rats; Rats, Sprague-Dawley; Substance P; Trachea; Vagus Nerve | 1992 |
The effect of Ca2+ channel modulators on vagally induced bronchoconstriction in the guinea-pig.
Topics: Animals; Atropine; Bronchoconstriction; Calcium Channel Blockers; Capsaicin; Electric Stimulation; Guinea Pigs; Male; Methacholine Chloride; omega-Conotoxin GVIA; Peptides, Cyclic; Substance P; Vagus Nerve | 1992 |
Pharmacology of idrapril: a new class of angiotensin converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Captopril; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hydroxylamines; Hypertension; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Substance P | 1992 |
CP-96,345, a non-peptide antagonist of substance P: I. Effects on the actions mediated by substance P and related tachykinins on the guinea-pig ileum and rabbit jejunum.
Topics: Animals; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Peristalsis; Rabbits; Stereoisomerism; Substance P; Tachykinins | 1992 |
Experimental peripheral neuropathy decreases the dose of substance P required to increase excitatory amino acid release in the CSF of the rat spinal cord.
Topics: Amino Acids; Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Dialysis; Male; Nociceptors; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Substance P | 1992 |
Carboxypeptidase M-like enzyme modulates the noncholinergic bronchoconstrictor response in guinea pig.
Topics: 3-Mercaptopropionic Acid; Animals; Bradykinin; Bronchoconstriction; Capsaicin; Electric Stimulation; GPI-Linked Proteins; Guinea Pigs; Histamine; Male; Metalloendopeptidases; Neurokinin A; Receptors, Cholinergic; Substance P; Vagus Nerve | 1992 |
The actions of capsaicin applied topically to the skin of the rat on C-fibre afferents, antidromic vasodilatation and substance P levels.
Topics: Administration, Topical; Animals; Capsaicin; Laser-Doppler Flowmetry; Neurons, Afferent; Nociceptors; Radioimmunoassay; Rats; Rats, Wistar; Regional Blood Flow; Skin; Substance P; Vasodilation | 1992 |
The isolated spinal cord-skin preparation of the newborn rat and effects of some algogenic and analgesic substances.
Topics: Action Potentials; Analgesics; Animals; Animals, Newborn; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Cerebrospinal Fluid; Enkephalin, Methionine; Morphine; Potassium Chloride; Prostaglandins E; Rats; Skin; Somatostatin; Spinal Cord; Substance P | 1992 |
Disulfiram administration affects substance P-like immunoreactive and monoaminergic neural systems in rodent brain.
Topics: Amino Acid Sequence; Animals; Biogenic Monoamines; Brain; Capsaicin; Chromatography, High Pressure Liquid; Disulfiram; Drug Synergism; Hypothalamus, Middle; Immunohistochemistry; Medulla Oblongata; Mice; Molecular Sequence Data; Pain Measurement; Pons; Preoptic Area; Radioimmunoassay; Spinal Cord; Substance P | 1990 |
Effects of capsaicin treatment on immunoglobulin secretion in the rat: further evidence for involvement of tachykinin-containing afferent nerves.
Topics: Animals; Antigen-Presenting Cells; Capsaicin; Cell Count; Female; Histamine; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Kinetics; Neurons, Afferent; Pyrilamine; Rats; Rats, Inbred Strains; Substance P; Tachykinins | 1990 |
Role of calcitonin gene-related peptide-containing nerves in the vascular adrenergic neurotransmission.
Topics: Animals; Blood Pressure; Blood Vessels; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Male; Norepinephrine; Peripheral Nerves; Rats; Rats, Inbred Strains; Splanchnic Circulation; Substance P; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin; Vasodilation | 1990 |
The effects of substance P and calcitonin gene-related peptide on the efflux of endogenous glutamate and aspartate from the rat spinal dorsal horn in vitro.
Topics: Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Capsaicin; Glutamates; Glutamic Acid; In Vitro Techniques; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1990 |
The distribution of substance P-containing nerves to the rat small intestine.
Topics: Animals; Capsaicin; Female; Ileum; Intestine, Small; Jejunum; Mesentery; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P | 1990 |
Administration of recombinant enkephalinase (neutral endopeptidase) prevents capsaicin-induced miosis in the rabbit eye in vivo.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; In Vitro Techniques; Neprilysin; Pupil; Rabbits; Recombinant Proteins; Substance P | 1990 |
Bile salt potentiates the action of capsaicin on sensory neurones of guinea-pig ileum.
Topics: Animals; Bile Acids and Salts; Capsaicin; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Neurons, Afferent; Substance P | 1990 |
Roles of substance P and somatostatin on transmission of nociceptive information induced by formalin in spinal cord.
Topics: Animals; Capsaicin; Cysteamine; Drug Interactions; Formaldehyde; Mice; Pain; Pain Measurement; Somatostatin; Spinal Cord; Substance P; Synaptic Transmission | 1990 |
Modification of serotonergic innervation of the rat spinal cord dorsal horn after neonatal capsaicin treatment.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Neurons, Afferent; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P | 1990 |
Release of sensory neuropeptides from dural venous sinuses of guinea pig.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cranial Sinuses; Female; Guinea Pigs; In Vitro Techniques; Male; Neurons, Afferent; Potassium; Substance P | 1990 |
Capsaicin selectively reduces airway responses to histamine, substance P and vagal stimulation.
Topics: Animals; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Methacholine Compounds; Respiratory System; Substance P; Vagus Nerve | 1990 |
Muscarinic supersensitivity in the rat urinary bladder after capsaicin pretreatment.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Electric Stimulation; Female; Immunohistochemistry; In Vitro Techniques; Muscle Contraction; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Substance P; Urinary Bladder | 1990 |
Dual effects of capsaicin on responses of the rabbit ear artery to field stimulation.
Topics: Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Ear, External; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vascular; Neurokinin A; Norepinephrine; Prostaglandins; Rabbits; Regional Blood Flow; Substance P; Sympathetic Nervous System; Synaptic Transmission | 1990 |
Suppression by neuropeptide Y of capsaicin-sensitive sensory nerve-mediated contraction in guinea-pig airways.
Topics: Animals; Atropine; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Neuropeptide Y; Propranolol; Substance P; Synaptic Transmission; Tetrodotoxin; Trachea | 1990 |
A bradykinin (BK)1 receptor antagonist blocks capsaicin-induced ear inflammation in mice.
Topics: Animals; Bradykinin; Capsaicin; Ear, External; Edema; Inflammation; Male; Mice; Receptors, Bradykinin; Receptors, Neurotransmitter; Substance P | 1990 |
Nasal mucosal permeability after methacholine, substance P, and capsaicin challenge in the rat.
Topics: Animals; Capsaicin; Fluorescein-5-isothiocyanate; Fluoresceins; Male; Methacholine Chloride; Methacholine Compounds; Nasal Mucosa; Permeability; Rats; Rats, Inbred Strains; Serum Albumin; Substance P; Thiocyanates | 1990 |
Effects of capsaicin, tachykinins, calcitonin gene-related peptide and bradykinin in the pig iris sphincter muscle.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Iris; Neurokinin A; Radioimmunoassay; Substance P; Swine; Tachykinins | 1990 |
Substance P is released from the endothelium of normal and capsaicin-treated rat hind-limb vasculature, in vivo, by increased flow.
Topics: Animals; Capsaicin; Endothelium, Vascular; Hindlimb; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Substance P | 1990 |
Prevention of cerebral vasospasm in the rat by depletion or inhibition of substance P in conducting vessels.
Topics: Animals; Capsaicin; Cerebral Angiography; Cerebral Arteries; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Substance P; Vasoconstriction | 1990 |
Capsaicin-induced bronchoconstriction and neuropeptide release in guinea pig perfused lungs.
Topics: Acetylcholine; Adenosine; Airway Resistance; Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Interactions; Glycopeptides; Guinea Pigs; Hydrogen-Ion Concentration; Lung; Lung Compliance; Male; Neurokinin A; Neuropeptides; Substance P; Tetrodotoxin | 1990 |
Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation.
Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Glycopeptides; In Vitro Techniques; Inflammation; Male; Neurons, Afferent; Neuropeptides; Rats; Rats, Inbred F344; Saline Solution, Hypertonic; Substance P; Trachea | 1990 |
Mechanism of tachyphylaxis associated with neurogenic plasma extravasation in the rat trachea.
Topics: Animals; Capillary Permeability; Capsaicin; Electric Stimulation; Female; Histamine; Rats; Stimulation, Chemical; Substance P; Tachykinins; Tachyphylaxis; Trachea; Vagus Nerve | 1990 |
Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice.
Topics: Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Neurokinin A; Rats; Rats, Inbred Strains; Recombinant Proteins; Spinal Cord; Spinal Nerve Roots; Substance P | 1990 |
Influence of capsaicin on the reagibility of the isolated guinea pig trachea.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Substance P; Trachea | 1990 |
Resorptive clearance and transepithelial potential difference in capsaicin-treated F344 rats.
Topics: Animals; Capsaicin; Epithelium; Male; Membrane Potentials; Organotechnetium Compounds; Pentetic Acid; Permeability; Rats; Rats, Inbred F344; Respiratory Physiological Phenomena; Respiratory System; Substance P; Technetium Tc 99m Pentetate | 1990 |
[Changes in the activity of the taste receptor apparatus and the preference for a sodium chloride solution in newborn rats receiving capsaicin].
Topics: Animals; Animals, Newborn; Capsaicin; Chorda Tympani Nerve; Drinking Behavior; Electrophysiology; Female; Male; Rats; Sodium Chloride; Solutions; Substance P; Taste Buds | 1990 |
Release of substance P-like immunoreactivity from the vascularly perfused rat stomach.
Topics: Animals; Bacitracin; Calcium; Capsaicin; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Gastric Mucosa; In Vitro Techniques; Naloxone; Perfusion; Potassium; Radioimmunoassay; Rats; Regional Blood Flow; Stomach; Substance P | 1990 |
Modulation of cholinergic neurotransmission in guinea-pig airways by opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Animals; Bronchi; Capsaicin; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Narcotics; Parasympathetic Nervous System; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance P; Synaptic Transmission; Trachea | 1990 |
Immunoblockade by a specific tachykinin antiserum of the non-cholinergic contractile responses in the guinea-pig isolated bronchus.
Topics: Airway Resistance; Animals; Bronchi; Capsaicin; Electric Stimulation; Eledoisin; Guinea Pigs; Immune Sera; In Vitro Techniques; Male; Muscle Contraction; Neurokinin A; Substance P | 1990 |
Intrinsic reflexes mediated via peptidergic neurons in the smooth muscle esophagus of the hen.
Topics: Animals; Atropine; Capsaicin; Chickens; Electric Stimulation; Esophagus; Female; Hexamethonium; Hexamethonium Compounds; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurons; Neuropeptides; Peristalsis; Reflex; Substance P | 1990 |
Capsaicin-sensitive and hexamethonium-insensitive circular muscle responses to mesenteric nerve stimulation in the isolated guinea pig ileum.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Substance P | 1990 |
Angiotensin converting enzyme inhibitors potentiate the bronchoconstriction induced by substance P in the guinea-pig.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bronchi; Capsaicin; Captopril; Drug Synergism; Enalaprilat; Guinea Pigs; In Vitro Techniques; Male; Neuropeptides; Prazosin; Serotonin; Substance P | 1990 |
Effect of capsaicin on the rabbit urinary bladder. What is the function of sensory nerves that contain substance P?
Topics: Animals; Capsaicin; Male; Muscle Contraction; Neurons, Afferent; Rabbits; Substance P; Urinary Bladder | 1990 |
Neurochemical evidence for the involvement of N-type calcium channels in transmitter secretion from peripheral endings of sensory nerves in guinea pigs.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Nerve Endings; Neurons, Afferent; omega-Conotoxins; Peptides, Cyclic; Substance P; Tetrodotoxin; Ureter | 1990 |
Effect of capsaicin on the release of substance P from rheumatoid arthritis and osteoarthritis synoviocytes in vitro.
Topics: Arthritis, Rheumatoid; Capsaicin; Humans; Osteoarthritis; Substance P; Synovial Fluid | 1990 |
Basal and stimulated release of substance P from dissociated cultures of vagal sensory neurons.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Chromatography, High Pressure Liquid; Kinetics; Neurons, Afferent; Nodose Ganglion; Phorbol 12,13-Dibutyrate; Potassium; Rats; Rats, Inbred Strains; Substance P; Vagus Nerve | 1990 |
Regional distribution of calcitonin gene-related peptide-, substance P-, cholecystokinin-, Met5-enkephalin-, and dynorphin A (1-8)-like materials in the spinal cord and dorsal root ganglia of adult rats: effects of dorsal rhizotomy and neonatal capsaicin.
Topics: Afferent Pathways; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Cholecystokinin; Dynorphins; Enkephalin, Methionine; Ganglia, Spinal; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Spinal Nerves; Substance P | 1990 |
Capsaicin pretreatment modifies hydrogen sulphide-induced pulmonary injury in rats.
Topics: Animals; Capsaicin; Hydrogen Sulfide; Inflammation; Lung; Lung Diseases; Male; Microscopy, Electron, Scanning; Neurons, Afferent; Rats; Rats, Inbred F344; Substance P | 1990 |
Sensory nerves, vascular endothelium and neurogenic relaxation of the guinea-pig isolated pulmonary artery.
Topics: Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neurons, Afferent; Pulmonary Artery; Receptors, Neurotransmitter; Receptors, Tachykinin; Ruthenium Red; Substance P | 1990 |
Studies on the vascular permeability induced by intrathecal substance P and bradykinin in the rat.
Topics: Adrenalectomy; Animals; Blood Proteins; Bradykinin; Capillary Permeability; Capsaicin; Decerebrate State; In Vitro Techniques; Injections, Spinal; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vagotomy | 1990 |
Effects of long-term laxative treatment on rat mesenteric resistance vessel responses in vitro.
Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Anthraquinones; Calcitonin Gene-Related Peptide; Capsaicin; Cathartics; Electric Stimulation; Female; Mesenteric Arteries; Rats; Rats, Inbred Strains; Senna Extract; Splanchnic Circulation; Substance P; Time Factors; Vasoconstriction | 1990 |
Effects of capsaicin on corneal wound healing.
Topics: Administration, Topical; Animals; Behavior, Animal; Capsaicin; Cornea; Eye; Female; Injections; Male; Rabbits; Substance P; Time Factors; Wound Healing | 1990 |
Substance P increases catecholamine secretion from perfused rat adrenal glands evoked by prolonged field stimulation.
Topics: Adrenal Glands; Animals; Capsaicin; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Epinephrine; Female; Norepinephrine; Rats; Splanchnic Nerves; Substance P | 1990 |
Evidence for the involvement of calcitonin gene-related peptide in the epithelium-dependent contraction of guinea-pig trachea in response to capsaicin.
Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide; Capsaicin; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Substance P; Trachea | 1990 |
Effects of N-methyl-D-aspartate antagonists and spantide on spinal reflexes and responses to substance P and capsaicin in isolated spinal cord preparations from mouse and rat.
Topics: Afferent Pathways; Analgesics; Animals; Capsaicin; Electrophysiology; In Vitro Techniques; Mice; N-Methylaspartate; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Spinal Nerve Roots; Substance P; Synapses | 1990 |
Substance P and CGRP mediate motor response of rabbit colon to capsaicin.
Topics: Acetylcholine; Adenosine Triphosphate; Afferent Pathways; Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Colon; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Neurons; Rabbits; Substance P; Tetrodotoxin | 1990 |
Glucocorticoids inhibit neurogenic plasma extravasation and prevent virus-potentiated extravasation in the rat trachea.
Topics: Animals; Body Weight; Capillary Permeability; Capsaicin; Dexamethasone; Kinetics; Mucous Membrane; Organ Size; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Rats; Rats, Inbred F344; Respiratory Tract Infections; Substance P; Trachea | 1990 |
Neural regulation of the interrelation between haustral and taenial motility in the rabbit proximal colon.
Topics: Animals; Atropine; Autonomic Agents; Capsaicin; Colon; Electric Stimulation; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Neurons; Peptides; Rabbits; Serotonin; Substance P | 1990 |
Serotonin modulates substance P-induced plasma extravasation and vasodilatation in rat skin by an action through capsaicin-sensitive primary afferent nerves.
Topics: Afferent Pathways; Animals; Blister; Capillary Permeability; Capsaicin; Inflammation; Male; Plasma; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin; Skin; Substance P; Time Factors; Vasodilation | 1990 |
Electrical behavior of myenteric neurons induced by mesenteric nerve stimulation in the guinea pig ileum.
Topics: Animals; Calcium; Capsaicin; Electric Stimulation; Electrophysiology; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; Magnesium; Mesentery; Myenteric Plexus; Nervous System Physiological Phenomena; Neurons; Substance P | 1990 |
Outflow facility in the monkey eye: effects of calcitonin gene-related peptide, cholecystokinin, galanin, substance P and capsaicin.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Capsaicin; Cholecystokinin; Dose-Response Relationship, Drug; Female; Galanin; Intraocular Pressure; Macaca fascicularis; Male; Neuropeptides; Peptides; Pupil; Substance P; Time Factors | 1990 |
Enzyme immunoassay for tachykinin-like immunoreactivity in the guinea pig spinal cord.
Topics: Acetylcholinesterase; Animals; Capsaicin; Eledoisin; Guinea Pigs; Immunoenzyme Techniques; Kassinin; Male; Neurokinin A; Neurokinin B; Physalaemin; Potassium; Radioimmunoassay; Spinal Cord; Substance P; Tachykinins; Thiorphan | 1991 |
Antinociception produced by capsaicin: spinal or peripheral mechanism?
Topics: Analgesics; Animals; Capsaicin; Guinea Pigs; In Vitro Techniques; Injections, Subcutaneous; Nerve Fibers; Neurons, Afferent; Neurons, Efferent; Peripheral Nerves; Spinal Cord; Substance P; Synaptic Transmission | 1990 |
Modulation of a peripheral inflammatory response to substance P by locally administered opioid receptor agonists.
Topics: Administration, Topical; Amino Acid Sequence; Animals; Blister; Capillary Permeability; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Inflammation; Male; Molecular Sequence Data; Naloxone; Oligopeptides; Perfusion; Peripheral Nerves; Rats; Skin; Substance P; Vasodilation | 1990 |
Capsaicin-sensitive nerves influence the release of atrial natriuretic factor by atrial stretch in the rat.
Topics: Animals; Atrial Function; Atrial Natriuretic Factor; Blood Volume; Calcitonin Gene-Related Peptide; Capsaicin; Heart; Heart Atria; Immunohistochemistry; In Vitro Techniques; Nerve Fibers; Perfusion; Rats; Rats, Inbred Strains; Stress, Mechanical; Substance P | 1990 |
[Relation of capsaicin-sensitive neurones to the effect of electro-acupuncture analgesia].
Topics: Acupuncture Analgesia; Animals; Capsaicin; Electroacupuncture; Male; Nerve Fibers; Neurons; Nociceptors; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Substance P | 1990 |
The utility of 2-hydroxypropyl-beta-cyclodextrin as a vehicle for the intracerebral and intrathecal administration of drugs.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; alpha-Cyclodextrins; Analgesia; Animals; beta-Cyclodextrins; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Ventricles; Cyclodextrins; Dimethyl Sulfoxide; Electroencephalography; Enkephalin, Leucine-2-Alanine; gamma-Cyclodextrins; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Motor Activity; Naloxone; Narcotics; Pain; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Solubility; Substance P; Time Factors | 1991 |
[Effect of capsaicin on the release of substance P from spinal cord and blood pressure].
Topics: Animals; Blood Pressure; Capsaicin; Epinephrine; Female; Ganglia, Autonomic; Heart Rate; Injections, Spinal; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1990 |
[Participation of the sensory nerves in the inflammatory response induced by irritants].
Topics: Animals; Capillary Permeability; Capsaicin; Carnitine; Denervation; Edema; Irritants; Male; Mice; Neurons, Afferent; Rats; Rats, Inbred Strains; Sciatic Nerve; Substance P | 1990 |
Inflammatory responses induced by substance P in rat paw.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Female; Histamine Release; Inflammation; Male; Rats; Rats, Inbred Strains; Substance P | 1990 |
Inhibitory renorenal reflexes: a role for substance P or other capsaicin-sensitive neurons.
Topics: Animals; Capsaicin; Chemoreceptor Cells; Dose-Response Relationship, Drug; Injections; Kidney; Male; Mechanoreceptors; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P | 1991 |
Effects of piperine on the motility of the isolated guinea-pig ileum: comparison with capsaicin.
Topics: Alkaloids; Animals; Anticonvulsants; Atropine; Benzodioxoles; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nerve Endings; Neurons, Afferent; Piperidines; Polyunsaturated Alkamides; Ruthenium Red; Substance P; Tachyphylaxis; Tetrodotoxin | 1990 |
Effect of endogenous tachykinins on neuro-effector transmission of vagal nerve in guinea-pig tracheal tissue.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Electric Stimulation; Female; Glycopeptides; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neprilysin; Neuroeffector Junction; Physostigmine; Substance P; Synaptic Transmission; Tachykinins; Trachea; Vagus Nerve | 1990 |
The skin hyperaemic response to local injection of substance P and capsaicin in diabetes mellitus.
Topics: Adult; Capsaicin; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; Humans; Injections, Intradermal; Male; Reference Values; Regional Blood Flow; Skin; Substance P; Ultrasonography | 1990 |
Capsaicin desensitization in vivo is inhibited by ruthenium red.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Injections, Subcutaneous; Nerve Endings; Neurons; Neurons, Afferent; Neuropeptides; Rats; Rats, Inbred Strains; Ruthenium Red; Substance P; Synaptic Transmission; Urinary Bladder | 1990 |
Chronic trigeminal ganglionectomy or topical capsaicin application to pial vessels attenuates postocclusive cortical hyperemia but does not influence postischemic hypoperfusion.
Topics: Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Cerebrovascular Circulation; Female; Ganglionectomy; Hyperemia; Ischemic Attack, Transient; Male; Nerve Fibers; Neuropeptide Y; Pia Mater; Substance P; Trigeminal Ganglion; Vasoactive Intestinal Peptide | 1991 |
Effects of capsaicin on mechanical, cellular, and mediator responses to antigen in sensitized guinea pigs.
Topics: Animals; Antigens; Bronchoalveolar Lavage Fluid; Capsaicin; Guinea Pigs; Histamine; Immunization; Leukotrienes; Lung Compliance; Male; Neurokinin A; Ovalbumin; Prostaglandins; Substance P; Thromboxane B2 | 1991 |
Tachykinin-mediated modulation of the primary antibody response in rats: evidence for mediation by an NK-2 receptor.
Topics: Animals; Animals, Newborn; Antibody Formation; Capsaicin; Denervation; Female; Immune System; Lymph Nodes; Male; Neurokinin A; Peptide Fragments; Peripheral Nerves; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tachykinins | 1991 |
Toluene diisocyanate contracts guinea pig bronchial smooth muscle by activating capsaicin-sensitive sensory nerves.
Topics: Animals; Anti-Bacterial Agents; Bronchi; Capsaicin; Glycopeptides; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Substance P; Toluene 2,4-Diisocyanate | 1991 |
Calcitonin gene-related peptide and human epicardial coronary arteries: presence, release and vasodilator effects.
Topics: Adult; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Female; Humans; In Vitro Techniques; Male; Nerve Endings; Ruthenium Red; Substance P; Vasodilation | 1991 |
Evidence that calcitonin gene-related peptide contributes to the capsaicin-induced relaxation of guinea pig cerebral arteries.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Arteries; Guinea Pigs; Immunohistochemistry; Muscle Relaxation; Muscle, Smooth, Vascular; Neurokinin A; Substance P; Vasodilation | 1990 |
Neonatal capsaicin treatment abolishes the nociceptive responses to intravenous 5-HT in the rat.
Topics: Animals; Animals, Newborn; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Hot Temperature; Injections, Intravenous; Male; Nociceptors; Pain; Rats; Rats, Inbred Strains; Reaction Time; Serotonin; Skin Physiological Phenomena; Spinal Cord; Substance P | 1991 |
Collagenase synthesis of rheumatoid arthritis synoviocytes: dose-dependent stimulation by substance P and capsaicin.
Topics: Arthritis, Rheumatoid; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Microbial Collagenase; Substance P; Synovial Fluid; Synovial Membrane | 1991 |
Ventilatory responses to hypoxia and hypercapnia in awake rats pretreated with capsaicin.
Topics: Animals; Animals, Newborn; Capsaicin; Chemoreceptor Cells; Hypercapnia; Hypoxia; Nerve Fibers; Rats; Rats, Inbred F344; Respiration; Substance P | 1991 |
Regulatory peptide and serotonin content and brush-border enzyme activity in the rat gastrointestinal tract following neonatal treatment with capsaicin; lack of effect on epithelial markers.
Topics: Alkaline Phosphatase; Aminopeptidases; Animals; Animals, Newborn; Biomarkers; Calcitonin Gene-Related Peptide; Capsaicin; CD13 Antigens; Chromaffin Granules; Epithelium; Intestinal Mucosa; Intestine, Small; Microvilli; Rats; Serotonin; Substance P; Vasoactive Intestinal Peptide | 1991 |
Capsaicin-evoked neuropeptide release is not dependent on membrane potential changes.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; In Vitro Techniques; Male; Membrane Potentials; Neurons, Afferent; Neuropeptides; Potassium; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1990 |
Gastric motility changes in capsaicin-induced cytoprotection in the rat stomach.
Topics: Animals; Capsaicin; Ethanol; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Substance P | 1991 |
Capsaicin enhances allergic contact dermatitis in the guinea pig.
Topics: Animals; Capsaicin; Dermatitis, Contact; Dinitrochlorobenzene; Drug Synergism; Female; Guinea Pigs; Immunization; Injections, Subcutaneous; Skin; Substance P; Time Factors | 1991 |
The role of substance P and calcitonin gene-related peptide containing nerve fibers in maintaining fungiform taste buds in the rat after a chronic chorda tympani nerve injury.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Chorda Tympani Nerve; Chronic Disease; Female; Immunohistochemistry; Nerve Fibers; Rats; Rats, Inbred Strains; Substance P; Taste Buds | 1991 |
Enkephalinase inhibitor potentiates substance P- and capsaicin-induced bronchial smooth muscle contractions in humans.
Topics: Adult; Aged; Aged, 80 and over; Bronchi; Bronchoconstriction; Capsaicin; Captopril; Drug Synergism; Glycopeptides; Humans; In Vitro Techniques; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Substance P | 1991 |
Regional differences in the distribution of nerve fibers showing substance P- and calcitonin gene-related peptide-like immunoreactivity in the rat larynx.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Laryngeal Nerves; Larynx; Male; Nerve Fibers; Rats; Rats, Inbred Strains; Substance P; Sympathectomy; Vagotomy | 1991 |
Neurogenic inflammation induced by capsaicin in patients with psoriasis.
Topics: Administration, Cutaneous; Adult; Age Factors; Capsaicin; Dose-Response Relationship, Drug; Erythema; Forearm; Humans; Inflammation; Psoriasis; Scleroderma, Systemic; Skin; Substance P | 1991 |
Effects of actinomycin D on airway constriction induced by tachykinins and capsaicin in guinea-pigs.
Topics: Airway Resistance; Animals; Capsaicin; Dactinomycin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Male; Neurokinin A; Substance P; Tachykinins; Trachea | 1991 |
Modulation of neural bronchoconstrictor responses in the guinea pig respiratory tract by vasoactive intestinal peptide.
Topics: Acetylcholine; Animals; Bronchi; Bronchoconstriction; Capsaicin; Electric Stimulation; Guinea Pigs; Male; Parasympathetic Nervous System; Substance P; Trachea; Vasoactive Intestinal Peptide | 1991 |
Capsaicin and sensory neuropeptide stimulation of goblet cell secretion in guinea-pig trachea.
Topics: Anesthesia, General; Animals; Axons; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Exocrine Glands; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Neuropeptides; Substance P; Time Factors; Trachea | 1990 |
Morphine, but not sodium cromoglycate, modulates the release of substance P from capsaicin-sensitive neurones in the rat trachea in vitro.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Bradykinin; Capsaicin; Cromolyn Sodium; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naloxone; Neurons; Potassium Chloride; Pyrrolidines; Rats; Rats, Inbred Strains; Substance P; Trachea | 1991 |
GABAB receptor modulation of the release of substance P from capsaicin-sensitive neurones in the rat trachea in vitro.
Topics: Animals; Baclofen; Bicuculline; Capsaicin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance P; Taurine; Trachea | 1991 |
Compartment analysis of vascular effects of neuropeptides and capsaicin in the pig nasal mucosa.
Topics: Animals; Atropine; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Capsaicin; Chlorisondamine; Nasal Mucosa; Neuropeptides; Substance P; Swine; Vascular Resistance; Vasoactive Intestinal Peptide | 1991 |
Cholinergic and noncholinergic submucosal neurons dilate arterioles in guinea pig colon.
Topics: Animals; Arterioles; Capsaicin; Cholinergic Fibers; Colon; Electric Stimulation; Guinea Pigs; Image Processing, Computer-Assisted; Immunohistochemistry; Intestinal Mucosa; Neurons; Substance P; Vasoconstriction; Vasodilation | 1991 |
Capsaicin-induced release of tachykinins: effects of enzyme inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Capsaicin; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Lung; Male; Neprilysin; Neurokinin A; Perfusion; Substance P | 1991 |
Neonatal capsaicin treatment alters basal pulmonary mechanics and response to methacholine in F344 rats.
Topics: Afferent Pathways; Airway Resistance; Animals; Animals, Newborn; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Male; Methacholine Chloride; Nerve Fibers; Rats; Rats, Inbred F344; Respiratory Mechanics; Substance P | 1991 |
Distribution of CGRP-, VIP-, D beta H-, SP-, and NPY-immunoreactive nerves in the periosteum of the rat.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dopamine beta-Hydroxylase; Female; Guanethidine; Immunohistochemistry; Mandible; Microscopy, Fluorescence; Nerve Fibers; Neuropeptide Y; Neuropeptides; Periosteum; Rats; Rats, Inbred Strains; Substance P; Sympathectomy, Chemical; Tibia; Vasoactive Intestinal Peptide | 1991 |
Association between histamine-containing mast cells and sensory nerves in the skin and airways of control and capsaicin-treated pigs.
Topics: Animals; Antigens, Helminth; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Hypersensitivity; Immunohistochemistry; Leukocytes; Mast Cells; Neurons, Afferent; Respiratory System; Skin; Substance P; Swine | 1991 |
Tachykinin antagonists and capsaicin-induced contraction of the rat isolated urinary bladder: evidence for tachykinin-mediated cotransmission.
Topics: Adenosine Triphosphate; Animals; Bombesin; Capsaicin; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Rats; Rats, Inbred Strains; Receptors, Purinergic; Substance P; Synaptic Transmission; Tachykinins; Urinary Bladder | 1991 |
Capsaicin-induced release of neurokinin A from muscle and mucosa of gastric corpus: correlation with capsaicin-evoked release of calcitonin gene-related peptide.
Topics: Animals; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Mucosa; Immunoenzyme Techniques; Male; Muscles; Neurokinin A; Radioimmunoassay; Rats; Rats, Inbred Strains; Staining and Labeling; Stomach; Substance P | 1991 |
[Effects of 7 drugs on cutaneous blood flow evoked by electric stimulation of rat sciatic nerve].
Topics: Analgesics; Animals; Capsaicin; Electric Stimulation; Extremities; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Rheology; Sciatic Nerve; Skin; Substance P | 1990 |
Ruthenium red antagonism of the effects of capsaicin mediated by extrinsic sensory nerves on myenteric plexus neurons of the isolated guinea-pig ileum.
Topics: Animals; Capsaicin; Electrophysiology; Guinea Pigs; Ileum; In Vitro Techniques; Microscopy, Electron; Myenteric Plexus; Nervous System Physiological Phenomena; Neurons; Ruthenium Red; Sensation; Substance P | 1991 |
Functional interactions between capsaicin-sensitive and cholinergic nerves in the guinea pig bronchus.
Topics: Animals; Atropine; Bronchi; Bronchoconstriction; Capsaicin; Cholinergic Fibers; Electric Stimulation; Guinea Pigs; Male; Neurokinin A; Neurons, Afferent; Substance P; Vagus Nerve | 1991 |
Heterogeneous involvement of endothelium in calcitonin gene-related peptide-induced relaxation in coronary arteries from rat.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Humans; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Ruthenium Red; Substance P | 1991 |
Calcitonin gene-related peptide is a potent vasodilator of bovine retinal arteries in vitro.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cattle; Dose-Response Relationship, Drug; In Vitro Techniques; Retinal Vessels; Ruthenium Red; Substance P; Vasodilator Agents | 1991 |
Behavioral sensitization to kainic acid and quisqualic acid in mice: comparison to NMDA and substance P responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Capsaicin; Concanavalin A; Drug Tolerance; GABA Antagonists; Glycine; Injections, Spinal; Kainic Acid; Mice; N-Methylaspartate; Quisqualic Acid; Spinal Cord; Substance P | 1991 |
Mechanical irritation induces neurogenic inflammation in the rat urethra.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Ganglionectomy; Inflammation; Neurons, Afferent; Rats; Rats, Inbred Strains; Stress, Mechanical; Substance P; Urethra; Urethritis; Urinary Catheterization | 1991 |
Decrease of duodenal calcitonin gene-related peptide- and substance P-like immunoreactivity in rat duodenal ulcers.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cysteamine; Denervation; Duodenal Ulcer; Duodenum; Epirizole; Female; Neurons, Afferent; Pyrimidines; Rats; Rats, Inbred Strains; Stomach Ulcer; Substance P | 1991 |
Relationship between sensory neuropeptides and other local vasoactive mediators in modulating gastric mucosal integrity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Blood Pressure; Capsaicin; Gastric Mucosa; Male; Microcirculation; Muscle, Smooth, Vascular; Neurons, Afferent; Neuropeptides; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Substance P; Vasodilation | 1991 |
Efferent function of capsaicin-sensitive nerves and neurogenic vasodilation in rat mesenteric circulation.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Relaxation; Neurons, Efferent; Potassium Chloride; Rats; Rats, Inbred Strains; Splanchnic Circulation; Substance P; Vasodilation | 1991 |
Sensory denervation with capsaicin reduces the liver collagen deposition induced by common bile duct obstruction in rats.
Topics: Animals; Biliary Tract; Body Weight; Capsaicin; Cholestasis; Collagen; Common Bile Duct Diseases; Eating; Hydroxyproline; Liver; Neurons, Afferent; Proteins; Rats; Rats, Inbred Strains; Serum Albumin; Substance P; Urinary Bladder | 1991 |
An immunocytochemical study of cutaneous innervation and the distribution of neuropeptides and protein gene product 9.5 in man and commonly employed laboratory animals.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Fluorescent Antibody Technique; Guinea Pigs; Humans; Neurokinin A; Neuropeptides; Oxidopamine; Rats; Rats, Inbred Strains; Skin; Substance P; Swine; Ubiquitin Thiolesterase | 1991 |
Activation of primary afferents in the rabbit ear by noxious heat.
Topics: Afferent Pathways; Animals; Bradykinin; Capsaicin; Ear; Hot Temperature; Pain; Potassium; Rabbits; Substance P | 1991 |
An examination of the proposed functional interaction of substance P and 5-HT in the guinea pig ileum.
Topics: Animals; Capsaicin; Captopril; Glycopeptides; Guinea Pigs; Ileum; Leucine; Muscle Contraction; Muscle, Smooth; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Serotonin; Substance P | 1991 |
Immunochemical characterization of SP processing intermediates in sensory ganglia.
Topics: Animals; Capsaicin; Ganglia, Spinal; Immune Sera; Peptide Fragments; Radioimmunoassay; Rats; Substance P | 1991 |
Potent anti-inflammatory action of calcitonin gene-related peptide.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; Cricetinae; Edema; Female; Histamine; Humans; Inflammation; Leukotriene B4; Male; Middle Aged; Mouth Mucosa; Rats; Serotonin; Skin; Skin Physiological Phenomena; Substance P | 1991 |
Differential effect on neuropeptide release of different concentrations of hydrogen ions on afferent and intrinsic neurons of the rat stomach.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Culture Media; Gastric Mucosa; Hydrogen-Ion Concentration; In Vitro Techniques; Muscle, Smooth; Neurons; Neurons, Afferent; Potassium; Protons; Radioimmunoassay; Rats; Rats, Inbred Strains; Stomach; Substance P; Vasodilation | 1991 |
Endogenous regulation of rat brain mast cell serotonin release.
Topics: Animals; beta-N-Acetylhexosaminidases; Brain; Calcium; Capsaicin; Cells, Cultured; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; In Vitro Techniques; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Potassium; Rats; Rats, Inbred Strains; Serotonin; Substance P | 1991 |
Developmental alterations in nociceptive threshold, immunoreactive calcitonin gene-related peptide and substance P, and fluoride-resistant acid phosphatase in neonatally capsaicin-treated rats.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Drug Resistance; Fluorides; Ganglia, Spinal; Histocytochemistry; Immunohistochemistry; Nociceptors; Rats; Rats, Inbred Strains; Sensory Thresholds; Spinal Nerve Roots; Substance P; Tissue Distribution | 1991 |
Effects of neonatal sympathectomy and capsaicin treatment on bone remodeling in rats.
Topics: Animals; Animals, Newborn; Bone Remodeling; Calcitonin Gene-Related Peptide; Capsaicin; Dopamine beta-Hydroxylase; Guanethidine; Male; Mandible; Nerve Fibers; Nerve Fibers, Myelinated; Neurons, Afferent; Osteoclasts; Rats; Rats, Inbred Strains; Substance P; Sympathectomy, Chemical; Tibia; Vasoactive Intestinal Peptide | 1991 |
Involvement of substance P in hyperalgesia induced by intrathecal galanin.
Topics: Animals; Antibodies, Monoclonal; Behavior, Animal; Capsaicin; Carrageenan; Galanin; Guinea Pigs; Ileum; In Vitro Techniques; Inflammation; Injections, Spinal; Male; Muscle, Smooth; Neurokinin A; Nociceptors; Pain; Peptides; Rats; Rats, Inbred Strains; Substance P | 1991 |
Studies of reflexogenic effects of capsaicin and neuropeptides on neural afferents in the dog parietal pericardium.
Topics: Afferent Pathways; Animals; Arachidonic Acid; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Dogs; Female; Heart Rate; Male; Neurokinin A; Neurokinin B; Neuropeptides; Pentolinium Tartrate; Pericardium; Propranolol; Substance P | 1991 |
Resiniferatoxin-, capsaicin- and CGRP-evoked porcine coronary vasodilatation is independent of EDRF mechanisms but antagonized by CGRP(8-37).
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Dactinomycin; Diterpenes; Methylene Blue; Neurokinin A; Nitric Oxide; Peptide Fragments; Substance P; Vasodilation | 1991 |
Neurogenic component of different models of acute inflammation in the rat knee joint.
Topics: Animals; Capsaicin; Carrageenan; Disease Models, Animal; Formaldehyde; Hindlimb; Inflammation; Joints; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Substance P; Uric Acid | 1991 |
Stimulation of frog ciliated cells in culture by acetylcholine and substance P.
Topics: Acetylcholine; Animals; Capsaicin; Cells, Cultured; Cilia; Epithelium; Microscopy; Mouth Mucosa; Mucociliary Clearance; Mucus; Palate; Rana pipiens; Stimulation, Chemical; Substance P; Video Recording | 1991 |
Similarities and differences in the action of resiniferatoxin and capsaicin on central and peripheral endings of primary sensory neurons.
Topics: Anesthesia; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Diterpenes; Ear, External; In Vitro Techniques; Male; Muscle Contraction; Nerve Endings; Neurons, Afferent; Peripheral Nerves; Rabbits; Rats; Rats, Inbred Strains; Reflex; Ruthenium Red; Spinal Cord; Substance P; Urinary Bladder; Urination; Vas Deferens | 1990 |
Involvement of afferent nerves in pulpal blood-flow reactions in response to clinical and experimental procedures in the cat.
Topics: Administration, Topical; Animals; Bradykinin; Capsaicin; Cats; Dental Cavity Preparation; Dental Pulp; Electric Stimulation; Ganglia, Sympathetic; Injections, Intravenous; Lasers; Male; Mandibular Nerve; Neurons, Afferent; Percussion; Regional Blood Flow; Substance P; Tooth | 1991 |
Regulation of cardiovascular sympathetic neurons by substance P and gamma-aminobutyric acid in the rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Heart Rate; Injections, Spinal; Male; Muscimol; Neurons; Neuropeptide Y; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P; Sympathetic Nervous System | 1991 |
Peptidergic innervation of mesenteric lymphatics in guinea pigs: an immunocytochemical and pharmacological study.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Immunohistochemistry; Lymphatic System; Mesenteric Arteries; Mesenteric Veins; Mesentery; Oxidopamine; Receptors, Gastrointestinal Hormone; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Vasoactive Intestinal Peptide; Substance P; Vasoactive Intestinal Peptide | 1991 |
Effect of capsaicin on carrageenan-induced inflammation in rat pleurisy and exudate substance P level.
Topics: Animals; Capsaicin; Carrageenan; Exudates and Transudates; Male; Pleurisy; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P | 1991 |
Hypothermia augments non-cholinergic neuronal bronchoconstriction in pithed guinea-pigs.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Azepines; Body Temperature; Bronchoconstriction; Capsaicin; Decerebrate State; Electric Stimulation; Guinea Pigs; Male; Morphine; Ouabain; Pentolinium Tartrate; Propranolol; Pyrilamine; Spinal Cord; Substance P; Sympathetic Nervous System; Tubocurarine | 1991 |
Ruthenium red and capsaicin induce a neurogenic inflammatory response in the rabbit eye: effects of omega-conotoxin GVIA and tetrodotoxin.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Capsaicin; Eye; Female; Inflammation; Intraocular Pressure; Male; Miosis; Neurokinin A; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic; Rabbits; Ruthenium Red; Substance P; Tetrodotoxin | 1991 |
The effects of neonatal capsaicin administration on trigeminal nerve chemoreceptors in the rat nasal cavity.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Chemoreceptor Cells; Electric Stimulation; Epithelial Cells; Epithelium; Immunoenzyme Techniques; Nerve Fibers; Olfactory Mucosa; Rats; Rats, Inbred Strains; Substance P; Trigeminal Nerve | 1991 |
Axon reflex vasodilatation in human skin measured by a laser Doppler technique.
Topics: Adult; Axons; Blood Flow Velocity; Capsaicin; Female; Forearm; Histamine; Histamine Antagonists; Humans; Lasers; Male; Middle Aged; Reflex; Skin; Substance P; Vasodilation | 1991 |
Degranulation of eosinophilic granule cells induced by capsaicin and substance P in the intestine of the rainbow trout (Oncorhynchus mykiss Walbaum).
Topics: Animals; Capsaicin; Cytoplasmic Granules; Immunity, Cellular; Intestines; Microscopy, Electron; Neuroimmunomodulation; Serotonin; Substance P; Trout | 1991 |
Modulation by adrenergic transmitters of the efferent function of capsaicin-sensitive nerves in cardiac tissue.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Conduction System; Imidazoles; In Vitro Techniques; Male; Myocardial Contraction; Neurokinin A; Neurons, Afferent; Neuropeptide Y; Norepinephrine; Phenoxybenzamine; Substance P | 1991 |
Capsazepine, a novel capsaicin antagonist, selectively antagonises the effects of capsaicin in the mouse spinal cord in vitro.
Topics: Action Potentials; Afferent Pathways; Animals; Capsaicin; Electric Stimulation; Ganglia, Spinal; Mice; Receptors, Drug; Spinal Cord; Substance P | 1991 |
Influence of perivascular peptides on endoneurial blood flow and microvascular resistance in the sciatic nerve of the rat.
Topics: Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Sciatic Nerve; Substance P; Vasa Nervorum; Vascular Resistance; Vasodilation | 1991 |
Capsaicin effects on muscularis mucosa of opossum esophagus: substance P release from afferent nerves?
Topics: Acetylcholine; Animals; Autacoids; Capsaicin; Electric Stimulation; Esophagus; Intercellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Opossums; Peptides; Substance P; Time Factors | 1985 |
Possible involvement of substance P in the contraction produced by periarterial nerve stimulation in the rat ileum.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Electric Stimulation; Guanethidine; Ileum; In Vitro Techniques; Indomethacin; Male; Mesentery; Muscle Contraction; Muscle, Smooth; Physostigmine; Rats; Rats, Inbred Strains; Substance P; Synaptic Transmission; Tetraethylammonium Compounds | 1985 |
Substance P antagonists and mucociliary activity in rabbit.
Topics: Animals; Bradykinin; Capsaicin; Cilia; Female; Male; Maxillary Sinus; Methacholine Chloride; Methacholine Compounds; Peptide Fragments; Rabbits; Substance P; Time Factors | 1985 |
Pharmaco-mechanical coupling in the response to acetylcholine and substance P in the smooth muscle of the rat iris sphincter.
Topics: Acetylcholine; Animals; Barium; Calcium; Capsaicin; Electric Stimulation; Iris; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin | 1985 |
Bombesin-like immunoreactivity in the central nervous system of capsaicin-treated rats: a radioimmunoassay and immunohistochemical study.
Topics: Animals; Animals, Newborn; Bombesin; Capsaicin; Central Nervous System; Hypothalamus; Immunochemistry; Medulla Oblongata; Neurotensin; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P; Thalamus | 1985 |
Possible involvement of substance P immunoreactive nerves in the mediation of nicotine-induced contractile responses in isolated guinea pig bronchus.
Topics: Animals; Bronchi; Capsaicin; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nicotine; Substance P | 1985 |
Effects of the substance P antagonist [D-Arg1,D-Pro2,D-Trp7,9,Leu11]SP on miosis caused by echothiophate iodide or pilocarpine hydrochloride.
Topics: Animals; Capsaicin; Echothiophate Iodide; Eye; Female; Male; Pilocarpine; Pupil; Rabbits; Radioimmunoassay; Substance P | 1985 |
Use of immunoblockade to study the involvement of peptidergic afferent nerves in the intestinal vasodilatory response to capsaicin in the dog.
Topics: Animals; Capsaicin; Cholecystokinin; Dogs; Female; Intestines; Male; Neurons, Afferent; Peptides; Regional Blood Flow; Splanchnic Circulation; Substance P; Vasoactive Intestinal Peptide; Vasodilation | 1985 |
Does capsaicin cause reflex bronchospasm in guinea-pigs?
Topics: Animals; Autonomic Agents; Bronchial Spasm; Capsaicin; Female; Guinea Pigs; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Male; Morphine; Naloxone; Neurons, Afferent; Pulmonary Circulation; Reflex; Respiration; Substance P | 1985 |
Altered respiratory response to substance P in capsaicin-treated rats.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Brain Chemistry; Capsaicin; Captopril; Female; Injections, Intraventricular; Male; Nerve Tissue Proteins; Oxygen Consumption; Rats; Rats, Inbred Strains; Respiration; Serotonin; Substance P; Time Factors | 1985 |
Capsaicin reduces substance P immunoreactivity in the lateral nucleus of the solitary tract and nodose ganglion.
Topics: Animals; Animals, Newborn; Capsaicin; Fluorescent Antibody Technique; Medulla Oblongata; Nodose Ganglion; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Vagus Nerve | 1985 |
Abrogation of peripheral cholecystokinin-satiety in the capsaicin treated rat.
Topics: Aging; Animals; Animals, Newborn; Biological Transport; Capsaicin; Cholecystokinin; Fasting; Feeding Behavior; Insulin; Obesity; Rats; Rats, Inbred Strains; Satiation; Satiety Response; Somatostatin; Substance P; Vagus Nerve; Ventromedial Hypothalamic Nucleus | 1985 |
Acetylsalicylic acid, paracetamol and morphine inhibit behavioral responses to intrathecally administered substance P or capsaicin.
Topics: Acetaminophen; Animals; Aspirin; Behavior, Animal; Capsaicin; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Morphine; Pain; Substance P | 1985 |
Evidence for substance P-immunoreactive spinal afferents that mediate bronchoconstriction.
Topics: Afferent Pathways; Airway Resistance; Animals; Bronchi; Capsaicin; Female; Fluorescent Antibody Technique; Guinea Pigs; Lung; Male; Muscle, Smooth; Norepinephrine; Pulmonary Artery; Stellate Ganglion; Substance P; Trachea; Vagus Nerve | 1985 |
Capsaicin in adult frogs: effects on nociceptive responses to cutaneous stimuli and on nervous tissue concentrations of immunoreactive substance P, somatostatin and cholecystokinin.
Topics: Animals; Brain Chemistry; Capsaicin; Cholecystokinin; Chromatography, Gel; Electric Stimulation; Hot Temperature; Nerve Tissue; Pain; Radioimmunoassay; Rana esculenta; Sensory Thresholds; Somatostatin; Spinal Cord; Stimulation, Chemical; Substance P; Time Factors | 1985 |
Multiple tachykinins (neurokinin A, neuropeptide K and substance P) in capsaicin-sensitive sensory neurons in the guinea-pig.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fluorescent Antibody Technique; Guinea Pigs; Nerve Tissue Proteins; Neurokinin A; Neurons, Afferent; Radioimmunoassay; Substance P; Tachykinins; Terminology as Topic; Tissue Distribution | 1985 |
Simultaneous release of several tachykinins and calcitonin gene-related peptide from rat spinal cord slices.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; Female; In Vitro Techniques; Male; Nerve Tissue Proteins; Neurokinin A; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1986 |
Non-cholinergic inotropic responses evoked by electric field stimulation in the isolated rat urinary bladder. Possible participation of substance P.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder | 1985 |
Innervation of guinea pig heart by neurons sensitive to capsaicin.
Topics: Animals; Capsaicin; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Guinea Pigs; Heart; Male; Myocardium; Neurons, Afferent; Substance P | 1986 |
The role of sensory fibres in the rat splanchnic nerve in the regulation of adrenal medullary secretion during stress.
Topics: Adrenal Medulla; Animals; Blood Glucose; Capsaicin; Cold Temperature; Epinephrine; Insulin; Norepinephrine; Rats; Rats, Inbred BUF; Splanchnic Nerves; Stress, Physiological; Substance P; Sympathetic Nervous System | 1986 |
Behavioral and neurochemical changes after intracisternal capsaicin treatment of the guinea pig.
Topics: Animals; Behavior, Animal; Capsaicin; Female; Guinea Pigs; Injections, Intraventricular; Male; Medulla Oblongata; Nasal Mucosa; Nerve Tissue Proteins; Neurokinin A; Substance P; Time Factors; Trigeminal Nucleus, Spinal | 1986 |
Correlation of mitochondrial swelling after capsaicin treatment and substance P and somatostatin immunoreactivity in small neurons of dorsal root ganglion in the rat.
Topics: Animals; Capsaicin; Ganglia, Spinal; Male; Microscopy, Electron; Mitochondrial Swelling; Neurons, Afferent; Rats; Rats, Inbred Strains; Somatostatin; Staining and Labeling; Substance P; Time Factors | 1986 |
Distribution of substance K (neurokinin A) in the brain and peripheral tissues of rats.
Topics: Animals; Capsaicin; Central Nervous System; Chromatography, High Pressure Liquid; Female; Ileum; Male; Nerve Tissue Proteins; Neurokinin A; Radioimmunoassay; Rats; Rats, Inbred Strains; Submandibular Gland; Substance P; Vas Deferens | 1986 |
Capsaicin stimulates mucociliary activity by releasing substance P and acetylcholine.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Cilia; Dose-Response Relationship, Drug; Female; Guanethidine; Hexamethonium Compounds; Male; Maxillary Sinus; Phentolamine; Propranolol; Rabbits; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Time Factors | 1986 |
Evidence that sensory neurons participate in the non-cholinergic, non-adrenergic contractile response of the guinea-pig ileum.
Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Guanethidine; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons, Afferent; Substance P | 1986 |
Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: distribution and quantitative differences between the iris and cerebral artery with special reference to substance P.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Arteries; Fluorescent Antibody Technique; Iris; Nerve Fibers; Nerve Tissue Proteins; Rats; Substance P; Trigeminal Ganglion; Trigeminal Nerve; Trigeminal Nucleus, Spinal | 1986 |
Evidence for glycoconjugate in nociceptive primary sensory neurons and its origin from the Golgi complex.
Topics: Animals; Biological Transport; Capsaicin; Central Nervous System; Colchicine; Galactose; Ganglia, Spinal; Golgi Apparatus; Immunoenzyme Techniques; Male; Neurons, Afferent; Nociceptors; Rats; Substance P | 1986 |
Effects of capsaicin on vascular smooth muscle.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Capsaicin; Carotid Arteries; Cats; Cerebral Arteries; Electric Stimulation; Endothelium; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Substance P | 1986 |
Capsaicin induces a depletion of calcitonin gene-related peptide (CGRP)-immunoreactive nerves in the cardiovascular system of the guinea pig and rat.
Topics: Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Cardiovascular System; Female; Guinea Pigs; Heart; Heart Conduction System; Male; Nerve Tissue Proteins; Neurons; Rats; Rats, Inbred Strains; Substance P; Veins | 1986 |
Autonomic mechanisms underlying capsaicin induced oral sensations and salivation in man.
Topics: Adolescent; Adult; Amylases; Autonomic Nervous System; Capsaicin; Citrates; Citric Acid; Female; Humans; Male; Middle Aged; N-Methylscopolamine; Nicotine; Palate; Saliva; Salivation; Scopolamine Derivatives; Secretory Rate; Substance P; Taste; Tongue | 1986 |
Non-cholinergic transmission in a sympathetic ganglion of the guinea-pig elicited by colon distension.
Topics: Action Potentials; Animals; Capsaicin; Colon; Ganglia, Sympathetic; Guinea Pigs; Male; Membrane Potentials; Neural Conduction; Pressure; Substance P; Synapses; Synaptic Transmission; Tachyphylaxis; Tetrodotoxin | 1986 |
Immunochemical studies of substance P and cholecystokinin octapeptide recovery in dorsal horn following unilateral lumbosacral ganglionectomy.
Topics: Afferent Pathways; Animals; Capsaicin; Cats; Enkephalin, Methionine; Functional Laterality; Ganglia, Spinal; Histocytochemistry; Nerve Crush; Nerve Regeneration; Radioimmunoassay; Sincalide; Spinal Cord; Substance P | 1986 |
Electrophysiological evidence for a presynaptic mechanism of morphine withdrawal in the neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; In Vitro Techniques; Membrane Potentials; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Substance Withdrawal Syndrome; Synapses | 1986 |
Analgesic activities of spinal cord substance P antagonists implicate substance P as a neurotransmitter of pain sensation.
Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Injections, Spinal; Iodine Radioisotopes; Mice; Pain; Piperazines; Somatostatin; Substance P | 1986 |
Effects of neurokinin A, substance P and electrical stimulation on the rabbit iris sphincter muscle.
Topics: Amino Acid Sequence; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Neurokinin A; Neuropeptides; Rabbits; Substance P | 1986 |
Tachykinins and calcitonin gene-related peptide in relation to peripheral functions of capsaicin-sensitive sensory neurons.
Topics: Animals; Blood Proteins; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Female; Guinea Pigs; Hemodynamics; Histocytochemistry; Humans; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Neuropeptides; Substance P; Tachykinins; Tissue Distribution; Uterine Contraction | 1986 |
Enkephalin and capsaicin-resistant substance P-like immunoreactivities in intra-ocular grafts of different fetal spinal cord areas.
Topics: Animals; Anterior Chamber; Capsaicin; Enkephalins; Female; Fluorescent Antibody Technique; Graft Survival; Iris; Male; Nerve Fibers; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1986 |
[Pharmaco-histochemical study of monoamine-containing cells in the taste buds as affected by capsaicin-induced substance P deficiency].
Topics: Animals; Capsaicin; Rana temporaria; Serotonin; Substance P; Taste Buds | 1986 |
Influence of substance P on ciliary beat frequency in airway isolated preparations.
Topics: Animals; Capsaicin; Child; Child, Preschool; Cilia; Guinea Pigs; Humans; In Vitro Techniques; Rabbits; Respiratory System; Species Specificity; Substance P | 1986 |
A pharmacological and immunohistochemical study of the splanchnic innervation of ileal longitudinal muscle in the toad Bufo marinus.
Topics: Animals; Bufo marinus; Capsaicin; Chymotrypsin; Denervation; Female; Ileum; Immunologic Techniques; Male; Muscle Contraction; Nerve Fibers; Splanchnic Nerves; Substance P | 1986 |
Intrathecal injection of capsaicin can be used as a behavioural nociceptive test in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Capsaicin; Injections, Spinal; Kainic Acid; Male; Mice; Pain Measurement; Receptors, Purinergic; Substance P | 1986 |
Capsaicin induced release of multiple tachykinins (substance P, neurokinin A and eledoisin-like material) from guinea-pig spinal cord and ureter.
Topics: Animals; Capsaicin; Eledoisin; Female; Guinea Pigs; Male; Neurokinin A; Neuropeptides; Proteinuria; Radioimmunoassay; Spinal Cord; Substance P; Tachykinins; Ureter | 1986 |
Neonatal capsaicin modifies morphine withdrawal signs in the rat.
Topics: Animals; Animals, Newborn; Capsaicin; Female; Male; Morphine; Naloxone; Nasal Mucosa; Rats; Rats, Inbred Strains; Salivation; Substance P; Substance Withdrawal Syndrome; Tears | 1986 |
The effect of capsaicin on some experimental inflammations in human skin.
Topics: Capsaicin; Dermatitis; Dermatitis, Contact; Erythema; Histamine Antagonists; Humans; Substance P; Tuberculin Test; Urticaria | 1986 |
Dual capsaicin effects on ureteric motility: low dose inhibition mediated by calcitonin gene-related peptide and high dose stimulation by tachykinins?
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemodynamics; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Neurokinin A; Neuropeptides; Substance P; Tachykinins; Ureter | 1986 |
Capsaicin treatment attenuates the reflex excitation of sympathetic activity caused by chemical stimulation of intestinal afferent nerves.
Topics: Animals; Bradykinin; Capsaicin; Ganglia, Spinal; Intestines; Kidney; Male; Membrane Potentials; Neurons, Afferent; Radioimmunoassay; Rats; Reflex; Substance P; Sympathetic Nervous System | 1986 |
Corticotropin-releasing factor immunostaining in the rat spinal cord and medulla oblongata: an unexpected form of cross-reactivity with substance P.
Topics: Amino Acid Sequence; Animals; Capsaicin; Corticotropin-Releasing Hormone; Fluorescent Antibody Technique; Hypothalamus; Male; Medulla Oblongata; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Trigeminal Nucleus, Spinal | 1986 |
Cardiovascular reflexes mediated by capsaicin sensitive cardiac afferent neurones in the dog.
Topics: Animals; Blood Pressure; Capsaicin; Coronary Vessels; Dogs; Female; Heart; Heart Rate; Injections, Intravenous; Male; Neurons, Afferent; Reflex; Substance P; Sympathetic Nervous System; Vagotomy | 1986 |
Neurochemical and antinociceptive effects of intrathecal capsaicin in the rat.
Topics: Animals; Capsaicin; Rats; Spinal Cord; Substance P | 1986 |
Intrathecal administration of substance P enhances cutaneous plasma protein extravasation in pentobarbital anaesthetized rats.
Topics: Animals; Blood Proteins; Capillary Permeability; Capsaicin; Decerebrate State; Hemodynamics; Injections, Intravenous; Injections, Spinal; Male; Neurotensin; Pentobarbital; Rats; Rats, Inbred Strains; Skin; Substance P | 1987 |
Comparison of the bronchoconstrictor and cardiovascular effects of some tachykinins in guinea pigs.
Topics: Airway Resistance; Animals; Blood Pressure; Bronchi; Capsaicin; Eledoisin; Female; Guinea Pigs; Kinins; Male; Morphine; Physalaemin; Substance P | 1987 |
Substance P-like immunoreactivity in rat forebrain leptomeninges and cerebral vessels originates from the trigeminal but not sympathetic ganglia.
Topics: Animals; Capsaicin; Circle of Willis; Cornea; Ganglia, Sympathetic; Histocytochemistry; Hydroxydopamines; Meninges; Nerve Fibers; Oxidopamine; Rats; Substance P; Sympathectomy, Chemical; Trigeminal Ganglion; Trigeminal Nerve | 1987 |
Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Neuropeptides; Nociceptors; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1987 |
Neuroendocrine and behavioral effects of intrathecal capsaicin in adult female rats.
Topics: Animals; Capsaicin; Estrus; Female; Fertility; Genitalia, Female; Injections, Spinal; Ovary; Pseudopregnancy; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Substance P | 1987 |
Substance P-inducing massive postmortem bronchoconstriction in guinea pig lungs.
Topics: Animals; Bronchial Spasm; Capsaicin; Chlorisondamine; Guinea Pigs; Male; Postmortem Changes; Substance P; Tetrodotoxin; Total Lung Capacity; Vital Capacity | 1987 |
Noncholinergic contractile response to nicotine in the guinea pig isolated tracheal smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Autonomic Nervous System; Capsaicin; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Substance P; Trachea | 1987 |
The role of substance P in the human urinary bladder.
Topics: Atropine; Capsaicin; Carbachol; Electric Stimulation; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Substance P; Urinary Bladder | 1987 |
Effects of age on the axon reflex response to noxious chemical stimulation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Axons; Capsaicin; Humans; Middle Aged; Reflex; Skin; Stimulation, Chemical; Substance P | 1986 |
Capsaicin in the treatment of dermatologic disease.
Topics: Capsaicin; Herpes Zoster; Humans; Neuralgia; Ointments; Psoriasis; Substance P | 1987 |
The correlation between sensory-efferent functions mediated by the capsaicin-sensitive neurons and substance P content of the rat urinary bladder.
Topics: Animals; Capsaicin; Denervation; Electric Stimulation; Ganglia, Autonomic; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Rats; Substance P; Urinary Bladder | 1987 |
Further studies on the mechanisms of the tachykinin-induced activation of micturition reflex in rats: evidence for the involvement of the capsaicin-sensitive bladder mechanoreceptors.
Topics: Aging; Animals; Capsaicin; Diphenhydramine; Electric Stimulation; In Vitro Techniques; Indomethacin; Kassinin; Male; Mechanoreceptors; Neurokinin A; Neurokinin B; Neuropeptides; Oligopeptides; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder; Urination | 1987 |
Tachykinins mediate the acute increase in airway responsiveness caused by toluene diisocyanate in guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Capsaicin; Cyanates; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Male; Neuropeptides; Pulmonary Edema; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Toluene 2,4-Diisocyanate; Trachea | 1987 |
Capsaicin-sensitive mechanisms and experimentally induced duodenal ulcers in rats.
Topics: Animals; Capillary Permeability; Capsaicin; Cysteamine; Duodenal Ulcer; Female; Gastrointestinal Motility; Pyrimidines; Rats; Rats, Inbred Strains; Substance P | 1987 |
The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neurons.
Topics: Animals; Blood Pressure; Capsaicin; Decerebrate State; Heart Rate; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P; Time Factors; Urinary Bladder | 1987 |
Effect of capsaicin upon afferent and efferent mechanisms of nociception and temperature regulation in birds.
Topics: Afferent Pathways; Animals; Birds; Body Temperature Regulation; Capsaicin; Chickens; Columbidae; Ducks; Efferent Pathways; Nociceptors; Pain; Rats; Sciatic Nerve; Spinal Cord; Substance P | 1987 |
Capsaicin desensitization protects from antigen-induced bronchospasm in conscious guinea-pigs.
Topics: Anaphylaxis; Animals; Bronchial Spasm; Capsaicin; Desensitization, Immunologic; Guinea Pigs; Male; Ovalbumin; Respiration; Substance P; Trachea | 1987 |
Substance P induces chemotaxis of neutrophils in normal and capsaicin-treated rats.
Topics: Animals; Capsaicin; Caseins; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Female; Neutrophils; Rats; Substance P | 1987 |
Comparison of the responses to the sensory neuropeptides, substance P, neurokinin A, neurokinin B and calcitonin gene-related peptide and to trigeminal nerve stimulation in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Eledoisin; Female; Iris; Kinins; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Neuropeptides; Physalaemin; Potassium Chloride; Rabbits; Substance P; Trigeminal Nerve | 1987 |
Involvement of substance P in the excitatory action of GABAA agonists on cholinergic neurons in the guinea-pig ileum.
Topics: Animals; Capsaicin; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Peptide Fragments; Substance P; Taurine | 1987 |
Regional differences in the effects of capsaicin and tachykinins on motor activity and vascular permeability of the rat lower urinary tract.
Topics: Animals; Capillary Permeability; Capsaicin; Electric Stimulation; Evans Blue; Ganglia; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neuropeptides; Rats; Rats, Inbred Strains; Substance P; Urinary Tract | 1987 |
Multiple tachykinin pools in sensory nerve fibres in the rabbit iris.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Iris; Male; Nerve Endings; Neurons, Afferent; Neuropeptides; Rabbits; Substance P; Tachykinins; Tachyphylaxis | 1987 |
Neurokinin A in capsaicin-sensitive neurons of the guinea-pig inferior mesenteric ganglia: an additional putative mediator for the non-cholinergic excitatory postsynaptic potential.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Electrophysiology; Female; Ganglia, Sympathetic; Guinea Pigs; Male; Neurokinin A; Neuropeptides; Neurotransmitter Agents; Radioimmunoassay; Substance P; Synaptic Transmission | 1987 |
Enhancement by parainfluenza 3 infection of contractile responses to substance P and capsaicin in airway smooth muscle from the guinea pig.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchi; Bronchial Spasm; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Lipoxygenase; Muscle, Smooth; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Substance P | 1987 |
Diminished flare response in neuropathic diabetic patients. Comparison of effects of substance P, histamine, and capsaicin.
Topics: Capsaicin; Diabetic Neuropathies; Female; Histamine; Humans; Male; Middle Aged; Nerve Fibers; Peripheral Nerves; Skin Tests; Substance P | 1987 |
Contribution of substance P to heat-induced edema in rat paw.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Edema; Histamine; Hot Temperature; Male; Pyridazines; Rats; Rats, Inbred Strains; Substance P | 1987 |
Effect of a substance P antagonist on capsaicin-induced nociceptive reflex in the isolated spinal cord-tail preparation of the rat.
Topics: Animals; Capsaicin; Electrophysiology; In Vitro Techniques; Nociceptors; Prostaglandins E; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Tail | 1987 |
Slow excitatory transmission in rat spinal dorsal horn and the effects of capsaicin.
Topics: Animals; Animals, Newborn; Capsaicin; Electric Stimulation; Electrophysiology; Ganglia, Spinal; In Vitro Techniques; Rats; Rats, Inbred Strains; Substance P; Synaptic Transmission | 1987 |
The acute effects of capsaicin on the cardiovascular system.
Topics: Animals; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Denervation; Heart Rate; Hexamethonium; Hexamethonium Compounds; Male; Morphine; Rats; Rats, Inbred Strains; Substance P; Vagus Nerve | 1987 |
Coexisting peptides in capsaicin-sensitive sensory neurons: release and actions in the respiratory tract of the guinea-pig.
Topics: Animals; Capsaicin; Guinea Pigs; In Vitro Techniques; Lung; Muscle Contraction; Neurokinin A; Neuropeptides; Perfusion; Substance P; Trachea; Vasodilation | 1987 |
Distribution, origin and sensitivity to capsaicin of primary afferent substance P-immunoreactive nerves in the heart.
Topics: Afferent Pathways; Animals; Capsaicin; Electrophysiology; Guinea Pigs; Heart; Immunohistochemistry; Nerve Fibers; Rats; Species Specificity; Substance P | 1987 |
Capsaicin and its effects on olfaction and trigeminal chemoreception.
Topics: Animals; Capsaicin; Chemoreceptor Cells; Male; Rats; Rats, Inbred Strains; Smell; Substance P; Taste; Trigeminal Nerve | 1987 |
Effects of capsaicin on release of substance P-like immunoreactivity and physiological parameters in isolated perfused guinea-pig heart.
Topics: Animals; Blood Pressure; Capsaicin; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Perfusion; Substance P | 1987 |
[Changes in nasal volume flow following local administration of neuropeptide substance P and capsaicin].
Topics: Capsaicin; Dose-Response Relationship, Drug; Humans; Manometry; Nasal Mucosa; Pulmonary Ventilation; Substance P | 1987 |
Substance P-like immunoreactivity in capsaicin-sensitive structures of the rat thymus.
Topics: Aging; Animals; Capsaicin; Chromatography, High Pressure Liquid; Cricetinae; Female; Guinea Pigs; Hydroxydopamines; Kinetics; Male; Mice; Norepinephrine; Oxidopamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Species Specificity; Substance P; Thymus Gland | 1987 |
Capsaicin enhances the non-adrenergic twitch response of rat vas deferens.
Topics: Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Hydroxydopamines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neuropeptides; Norepinephrine; Oxidopamine; Peptides; Rats; Rats, Inbred Strains; Reserpine; Substance P; Vas Deferens | 1987 |
Cardiovascular effects of substance P and capsaicin microinjected into the nucleus tractus solitarii of the rat.
Topics: Animals; Blood Pressure; Capsaicin; Heart Rate; Kinetics; Male; Medulla Oblongata; Microinjections; Rats; Rats, Inbred Strains; Substance P; Time Factors | 1987 |
The effect of substance P on the regional lymph node antibody response to antigenic stimulation in capsaicin-pretreated rats.
Topics: Animals; Animals, Newborn; Antibody Formation; Antigens; Capsaicin; Inflammation; Injections, Subcutaneous; Leukocyte Count; Lymph Nodes; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P | 1987 |
Capsaicin-induced corneal lesions in mice and the effects of chemical sympathectomy.
Topics: Animals; Animals, Newborn; Benzylamines; Capsaicin; Cornea; Hydroxydopamines; Male; Mice; Norepinephrine; Oxidopamine; Substance P; Sympathectomy, Chemical | 1987 |
Evidence for a visceral afferent origin of substance P-like immunoreactivity in lamina V of the rat thoracic spinal cord.
Topics: Animals; Capsaicin; Immunohistochemistry; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Spinal Cord; Splanchnic Nerves; Substance P; Viscera | 1987 |
Calcitonin gene-related peptide but not substance P mimics capsaicin-induced coronary vasodilation in the pig.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Endothelium, Vascular; Hemodynamics; In Vitro Techniques; Neuropeptides; Potassium; Substance P; Swine; Vasodilation | 1987 |
Substance P and cholecystokinin-like immunoreactive varicosities in somatosensory and autonomic regions of the rat spinal cord: a quantitative study of coexistence.
Topics: Animals; Autonomic Nervous System; Capsaicin; Cholecystokinin; Female; Immunohistochemistry; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1987 |
Responses to antidromic trigeminal nerve stimulation, substance P, NKA, CGRP and capsaicin in the rat eye.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Male; Neurokinin A; Neuropeptides; Pupil; Rats; Rats, Inbred Strains; Substance P; Trigeminal Nerve | 1987 |
Phosphoramidon potentiates the increase in lung resistance mediated by tachykinins in guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Bronchi; Capsaicin; Drug Synergism; Glycopeptides; Guinea Pigs; Male; Metalloendopeptidases; Neprilysin; Neuropeptides; Substance P; Tachykinins | 1988 |
Involvement of a peripheral site of action in the early phase of neuropeptide depletion following capsaicin desensitization.
Topics: Animals; Capsaicin; Male; Peripheral Nerves; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1987 |
Cutaneous lesions in capsaicin-pretreated rats. A trophic role of capsaicin-sensitive afferents?
Topics: Animals; Animals, Newborn; Behavior, Animal; Capillary Permeability; Capsaicin; Female; Hair; Hydrochloric Acid; Male; Neurons, Afferent; Neuropeptides; Rats; Skin; Skin Diseases; Skin Ulcer; Substance P; Tachykinins | 1987 |
Species-related variations in the effects of capsaicin on urinary bladder functions: relation to bladder content of substance P-like immunoreactivity.
Topics: Animals; Capillary Permeability; Capsaicin; Cricetinae; Decerebrate State; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Substance P; Urinary Bladder; Urinary Tract; Urination | 1987 |
Substance P-containing nerves mediate nicotine-induced contractions of rabbit bronchial smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Capsaicin; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nicotine; Physostigmine; Rabbits; Substance P | 1988 |
Release of substance P from the cat spinal cord.
Topics: 5,6-Dihydroxytryptamine; Analgesics; Animals; Blood Pressure; Capsaicin; Cats; Female; Intercellular Signaling Peptides and Proteins; Male; Naloxone; Neurotransmitter Agents; Peptides; Sciatic Nerve; Spinal Cord; Substance P; Sympathomimetics; Temperature; Time Factors | 1987 |
Responses of anterior hypothalamic-preoptic thermosensitive neurons to substance P and capsaicin.
Topics: Anesthesia; Animals; Body Temperature Regulation; Capsaicin; Electrophoresis; Hot Temperature; Hypothalamus, Anterior; Male; Microinjections; Neurons, Afferent; Preoptic Area; Rats; Rats, Inbred Strains; Substance P | 1988 |
Calcitonin gene-related peptide and the lung: neuronal coexistence with substance P, release by capsaicin and vasodilatory effect.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Guinea Pigs; Humans; Immunohistochemistry; In Vitro Techniques; Lung; Neurons; Neuropeptides; Rats; Substance P; Vasodilation | 1988 |
Capsaicin challenge, reflex bronchoconstriction, and local action of substance P.
Topics: Aerosols; Airway Resistance; Animals; Atropine; Blood Pressure; Bronchi; Capsaicin; Guinea Pigs; Lidocaine; Plethysmography; Reflex; Substance P; Vagus Nerve | 1988 |
Substance P content of the skin, neurogenic inflammation and numbers of C-fibres following capsaicin application to a cutaneous nerve in the rabbit.
Topics: Animals; Capsaicin; Female; Male; Microscopy, Electron; Nerve Fibers; Neuritis; Rabbits; Skin; Substance P; Time Factors | 1988 |
Simultaneous release of substance P- and calcitonin gene-related peptide (CGRP)-like immunoreactivity from isolated muscle of the guinea pig urinary bladder.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neurons, Afferent; Neuropeptides; Radioimmunoassay; Substance P; Swine; Tetrodotoxin; Urinary Bladder | 1988 |
Several neuropeptides determine the visceromotor response to capsaicin in the guinea-pig isolated ileal longitudinal muscle.
Topics: Animals; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Neuropeptides; Substance P | 1988 |
Treatment of oral postherpetic neuralgia with topical capsaicin.
Topics: Administration, Topical; Aged; Capsaicin; Herpes Zoster; Humans; Male; Mouth Mucosa; Neuralgia; Substance P | 1988 |
Tachykinin release from rat spinal cord in vitro and in vivo in response to various stimuli.
Topics: Animals; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Neuropeptides; Potassium; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Substance P; Tachykinins | 1988 |
Simultaneous release by bradykinin of substance P- and calcitonin gene-related peptide immunoreactivities from capsaicin-sensitive structures in guinea-pig heart.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Heart; In Vitro Techniques; Neuropeptides; Perfusion; Substance P | 1988 |
Investigation of mechanisms of the flare and wheal reactions in human skin by band method.
Topics: Adult; Axons; Capsaicin; Histamine; Humans; Neurotensin; Nicotine; Skin; Skin Tests; Substance P | 1988 |
Capsaicin-sensitive tachykinin-like immunoreactivity in the thymus of rats and guinea-pigs.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Cricetinae; Eledoisin; Guinea Pigs; Immunologic Techniques; Mice; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Species Specificity; Substance P; Tachykinins; Thymus Gland | 1988 |
Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds.
Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P | 1988 |
Neural pathways and pharmacological modulation of defecation reflex in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Defecation; Hexamethonium Compounds; Male; Naloxone; Neuropeptides; Phentolamine; Picrotoxin; Rats; Rats, Inbred Strains; Rectum; Reflex; Substance P | 1988 |
Effect of a tachykinin antagonist on a nociceptive reflex in the isolated spinal cord-tail preparation of the newborn rat.
Topics: Analgesics; Animals; Animals, Newborn; Calcium; Capsaicin; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Neuropeptides; Neurotransmitter Agents; Nociceptors; Rats; Reflex; Spinal Cord; Substance P; Tail; Thyrotropin-Releasing Hormone | 1988 |
Tachykinin-like immunoreactivity in the mammalian urinary bladder: correlation with the functions of the capsaicin-sensitive sensory nerves.
Topics: Animals; Capsaicin; Guinea Pigs; Male; Mice; Muscle Contraction; Neurokinin A; Neurons, Afferent; Neuropeptides; Phenoxybenzamine; Rats; Rats, Inbred Strains; Species Specificity; Substance P; Tachykinins; Urinary Bladder | 1988 |
Biochemical, anatomical and functional correlates of postnatal development of the capsaicin-sensitive innervation of the rat urinary bladder.
Topics: Acetylcholine; Aging; Animals; Capsaicin; Female; Male; Muscle Contraction; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1988 |
[Descending bulbospinal substance-P-containing pathway involved in the pressor response evoked by physostigmine].
Topics: Animals; Blood Pressure; Capsaicin; Heart Rate; Male; Medulla Oblongata; Physostigmine; Rats; Rats, Inbred Strains; Substance P | 1988 |
The antagonism induced by ruthenium red of the actions of capsaicin on the peripheral terminals of sensory neurons: further studies.
Topics: Animals; Calcium; Capsaicin; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neurons, Afferent; Rats; Rats, Inbred Strains; Ruthenium; Ruthenium Red; Substance P; Urinary Bladder | 1988 |
The effect of omega conotoxin GVIA, a peptide modulator of the N-type voltage sensitive calcium channels, on motor responses produced by activation of efferent and sensory nerves in mammalian smooth muscle.
Topics: Animals; Calcium Channel Blockers; Capsaicin; Duodenum; Guinea Pigs; In Vitro Techniques; Male; Mollusk Venoms; Muscle Contraction; Muscle, Smooth; Neuroeffector Junction; Neurons, Afferent; Neurons, Efferent; omega-Conotoxin GVIA; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder; Vas Deferens | 1988 |
[Effect of capsaicin on the solitary tract nucleus].
Topics: Afferent Pathways; Animals; Capsaicin; Cranial Nerves; Medulla Oblongata; Ranidae; Substance P | 1988 |
Effects of neuropeptide Y, calcitonin gene-related peptide, substance P, and capsaicin on cerebral arteries in man and animals.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Cerebral Arteries; Female; Humans; In Vitro Techniques; Male; Neuropeptide Y; Neuropeptides; Norepinephrine; Potassium; Substance P; Swine; Vasoconstriction | 1988 |
Neutral endopeptidase inhibitors potentiate substance P- and capsaicin-induced cough in awake guinea pigs.
Topics: Animals; Capsaicin; Cough; Drug Synergism; Glycopeptides; Guinea Pigs; Male; Neprilysin; Substance P; Thiorphan | 1988 |
Capsaicin-induced release of substance P-like immunoreactivity from the guinea pig stomach in vitro and in vivo.
Topics: Animals; Capsaicin; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Male; Neurons, Afferent; Substance P | 1988 |
Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation.
Topics: Animals; Bradykinin; Capsaicin; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Nervous System; Neurokinin A; Pulmonary Artery; Sensation; Substance P; Tachykinins; Trachea; Vagus Nerve | 1988 |
Substance P release from knee joint afferent terminals: modulation by opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Afferent Pathways; Animals; Capsaicin; Cats; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hindlimb; Joints; Narcotics; Pyrrolidines; Reference Values; Sciatic Nerve; Substance P; Sufentanil | 1988 |
Influence of epithelium on guinea pig airway responses to tachykinins: role of endopeptidase and cyclooxygenase.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Endopeptidases; Epithelium; Glycopeptides; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Prostaglandin-Endoperoxide Synthases; Substance P; Tachykinins; Trachea | 1989 |
Inhibitors of neutral endopeptidase potentiate electrically and capsaicin-induced noncholinergic contraction in guinea pig bronchi.
Topics: Animals; Bronchi; Capsaicin; Electric Stimulation; Glycopeptides; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Neprilysin; Substance P; Thiorphan | 1989 |
Regional differences in the motor response to capsaicin in the guinea-pig urinary bladder: relative role of pre- and postjunctional factors related to neuropeptide-containing sensory nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclic AMP; Guinea Pigs; Histamine; Immune Sera; In Vitro Techniques; Male; Muscle Contraction; Neurons, Afferent; Neuropeptides; Substance P; Tetrodotoxin; Urinary Bladder | 1988 |
Developmental alterations in thermal nociceptive threshold and the distribution of immunoreactive calcitonin gene-related peptide and substance P after neonatal administration of capsaicin in the rat.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Hot Temperature; Immunohistochemistry; Neuropeptides; Nociceptors; Rats; Rats, Inbred Strains; Sensory Thresholds; Spinal Cord; Substance P | 1989 |
Capsaicin-sensitive nerves are involved in bile-oleate-induced intestinal hyperemia.
Topics: Animals; Atropine; Bile; Blood Pressure; Capsaicin; Female; Heart Rate; Hexamethonium; Hexamethonium Compounds; Hyperemia; Immune Sera; Jejunum; Male; Mesenteric Arteries; Oleic Acid; Oleic Acids; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Reserpine; Sincalide; Splanchnic Circulation; Substance P; Vasoactive Intestinal Peptide | 1989 |
Co-existence and origin of peptidergic and adrenergic nerves in the guinea pig uterus. Retrograde tracing and immunocytochemistry, effects of chemical sympathectomy, capsaicin treatment and pregnancy.
Topics: Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cervix Uteri; Female; Fluorescent Antibody Technique; Ganglia, Spinal; Guinea Pigs; Hydroxydopamines; Immunohistochemistry; Neurokinin A; Neuropeptide Y; Neuropeptides; Oxidopamine; Pregnancy; Substance P; Swine; Sympathectomy, Chemical; Uterus | 1988 |
Release of substance P- and calcitonin gene-related peptide-like immunoreactivity and motor response of the isolated guinea pig gallbladder to capsaicin.
Topics: Animals; Atropine; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neuropeptides; Substance P | 1989 |
Stimulation of afferent fibres of the guinea-pig ureter evokes potentials in inferior mesenteric ganglion neurones.
Topics: Animals; Capsaicin; Female; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Nerve Fibers; Neurokinin A; Neurons; Neurons, Afferent; Substance P; Time Factors; Ureter | 1988 |
[Pharmacologic studies of cultivated human ciliated cells of the upper respiratory tract].
Topics: Ambroxol; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Cells, Cultured; Cilia; Clenbuterol; Humans; Nasal Mucosa; Neuropeptides; Substance P | 1988 |
Neonatal capsaicin treatment abolishes the modulations by opioids of substance P release from rat spinal cord slices.
Topics: Animals; Animals, Newborn; Capsaicin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Substance P | 1989 |
Distribution of calcitonin gene-related peptide-like immunoreactivity in various rat tissues: correlation with substance P and other tachykinins and sensitivity to capsaicin.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Male; Neuropeptides; Rats; Rats, Inbred Strains; Substance P; Tachykinins; Tissue Distribution | 1988 |
Effects of neuropeptides and capsaicin on tracheobronchial blood flow of the pig.
Topics: Animals; Bradykinin; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Injections, Intravenous; Neuropeptides; Peptide PHI; Regional Blood Flow; Substance P; Swine; Trachea; Vascular Resistance; Vasoactive Intestinal Peptide | 1989 |
Experimental bronchoalveolar lavage in guinea pigs--a useful tool to investigate the intrabronchial release of substance P.
Topics: Animals; Bronchi; Capsaicin; Female; Guinea Pigs; Male; Substance P; Therapeutic Irrigation | 1988 |
Tachykinin involvement in cutaneous anaphylaxis in the guinea pig.
Topics: Anaphylaxis; Animals; Capsaicin; Guinea Pigs; Injections, Intradermal; Male; Ovalbumin; Permeability; Receptors, Neurotransmitter; Receptors, Tachykinin; Skin; Substance P; Tachykinins | 1988 |
Enhanced airway responses to substance P after repeated challenge in guinea pigs.
Topics: Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Lung Compliance; Male; Muscle Contraction; Pyrilamine; Respiratory Physiological Phenomena; Respiratory System; Substance P | 1989 |
Acute effect of cigarette smoke on cytoplasmic motility of alveolar macrophages in dogs.
Topics: Acetylcholine; Animals; Capsaicin; Cytoplasm; Dogs; Ferrosoferric Oxide; Iron; Macrophages; Magnetics; Nicotine; Oxides; Reference Values; Respiration; Smoking; Substance P | 1989 |
Substance P induced hydrolysis of inositol phospholipids in rat skin in an in vivo model of inflammation.
Topics: Animals; Blister; Capillary Permeability; Capsaicin; Histamine; Hydrolysis; Inflammation; Phosphatidylinositols; Pyrilamine; Rats; Skin; Substance P | 1989 |
Vagal vasodilatory mechanisms in the pig bronchial circulation preferentially involves sensory nerves.
Topics: Animals; Atropine; Bronchial Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Chlorisondamine; Electric Stimulation; Female; Male; Neurons, Afferent; Neuropeptides; Substance P; Swine; Vagus Nerve; Vasodilation | 1989 |
Effects of substance P, calcitonin gene-related peptide and capsaicin on tension and membrane potential of pig coronary artery in vitro.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptides; Substance P; Swine | 1989 |
Effect of capsaicin on gastric corpus smooth muscle of the rat in vitro.
Topics: Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Dimethylphenylpiperazinium Iodide; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neuropeptides; Rats; Rats, Inbred Strains; Stomach; Substance P; Tachyphylaxis; Tetrodotoxin; Vasoactive Intestinal Peptide | 1989 |
Primary sensory neurones and naloxone-precipitated morphine withdrawal.
Topics: Animals; Blood Pressure; Capsaicin; Female; Male; Morphine Dependence; Naloxone; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Substance P; Substance Withdrawal Syndrome; Time Factors | 1989 |
Effects of capsaicin in rat and pigeon on peripheral nerves containing substance P and calcitonin gene-related peptide.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Columbidae; Cornea; Immunohistochemistry; Male; Neuropeptides; Peripheral Nerves; Rats; Rats, Inbred Strains; Substance P; Ureter | 1989 |
Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation.
Topics: Animals; Capsaicin; Carbachol; Edema; Histamine; Male; Neurons, Afferent; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Skin Physiological Phenomena; SRS-A; Substance P; Trachea | 1989 |
Substance P-mediated modulation of the primary antibody response.
Topics: Animals; Animals, Newborn; Antibody Formation; Capsaicin; Hemolytic Plaque Technique; Rats; Rats, Inbred Strains; Substance P | 1988 |
The effect of calcium free medium and nifedipine on the release of substance P-like immunoreactivity and contractions induced by capsaicin in the isolated guinea-pig and rat bladder.
Topics: Animals; Calcium; Capsaicin; Edetic Acid; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder | 1989 |
Treatment of apocrine chromhidrosis with topical capsaicin.
Topics: Administration, Topical; Adult; Age Factors; Apocrine Glands; Capsaicin; Face; Female; Humans; Lipofuscin; Pigmentation Disorders; Substance P; Sweat Gland Diseases; Sweat Glands | 1989 |
A comparison of bradykinin- and capsaicin-induced myocardial and coronary effects in isolated perfused heart of guinea-pig: involvement of substance P and calcitonin gene-related peptide release.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Circulation; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Neuropeptides; Radioimmunoassay; Substance P; Time Factors; Vasodilator Agents | 1989 |
Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs.
Topics: Aerosols; Animals; Antitussive Agents; Capsaicin; Cough; Guinea Pigs; Humans; Liposomes; Male; Neprilysin; Recombinant Proteins; Sodium Chloride; Substance P; Tachykinins | 1989 |
Cigarette smoke induces bronchoconstrictor hyperresponsiveness to substance P and inactivates airway neutral endopeptidase in the guinea pig. Possible role of free radicals.
Topics: Airway Resistance; Animals; Bronchi; Bronchial Provocation Tests; Capsaicin; Enzyme Activation; Free Radicals; Glycopeptides; Guinea Pigs; Male; Neprilysin; Nicotine; Smoking; Solutions; Substance P; Succinimides; Superoxide Dismutase | 1989 |
Substance P-induced cutaneous plasma extravasation in rats is mediated by NK-1 tachykinin receptors.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Evans Blue; Plasma; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin; Skin; Substance P; Tachykinins | 1989 |
Substance P-like immunoreactivity in sympathetic ganglion from toad.
Topics: Action Potentials; Animals; Anura; Capsaicin; Ganglia, Sympathetic; Immunohistochemistry; Mast Cells; Substance P; Synaptic Transmission | 1989 |
Thiorphan increases capsaicin-evoked release of substance P from slices of dorsal spinal cord of guinea pig.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Captopril; Female; Guinea Pigs; Kinetics; Male; Neprilysin; Neuropeptides; Spinal Cord; Substance P; Thiorphan | 1989 |
Capsaicin-induced vasodilatation of human coronary arteries in vitro is mediated by calcitonin gene-related peptide rather than substance P or neurokinin A.
Topics: Adult; Arteries; Biological Factors; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Female; Humans; Male; Muscle, Smooth, Vascular; Neurokinin A; Neuropeptides; Nitric Oxide; Somatostatin; Substance P; Vasoactive Intestinal Peptide; Vasodilator Agents | 1989 |
Capsaicin-sensitive nerves exert an inhibitory effect on the development of fibrin-induced pulmonary edema in rats.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Extracellular Space; Fibrin; Heart Rate; Lung; Male; Neuropeptides; Pulmonary Edema; Rats; Rats, Inbred Strains; Substance P; Vagotomy; Vagus Nerve | 1989 |
Effects of capsaicin pretreatment on neuropeptides and salivary secretion of rat parotid glands.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Female; Neuropeptides; Organ Size; Parasympathetic Nervous System; Parotid Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Salivation; Substance P; Tachykinins; Urinary Bladder; Vasoactive Intestinal Peptide | 1989 |
Virus induces airway hyperresponsiveness to tachykinins: role of neutral endopeptidase.
Topics: Animals; Bronchi; Capsaicin; Constriction, Pathologic; Electric Stimulation; Glycopeptides; Guinea Pigs; Male; Muscle, Smooth; Neprilysin; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Respiratory Tract Infections; Substance P; Tachykinins | 1989 |
Substance P immunoreactivity in the superior cervical ganglia of normotensive and genetically hypertensive rats.
Topics: Aging; Animals; Capsaicin; Ganglia, Sympathetic; Hypertension; Neurons, Afferent; Neuropeptide Y; Rats; Rats, Inbred Strains; Substance P | 1989 |
Desensitization and capsaicin-induced release of substance P-like immunoreactivity from guinea-pig ureter in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Capsaicin; Guinea Pigs; In Vitro Techniques; Mice; Neurons, Afferent; Substance P; Ureter | 1989 |
Regional differences in the motor and inflammatory responses to capsaicin in guinea pig airways. Correlation with content and release of substance P-like immunoreactivity.
Topics: Animals; Biomarkers; Blood Proteins; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Guinea Pigs; Male; Muscle Contraction; Neurokinin A; Neurons, Afferent; Respiratory Muscles; Substance P; Trachea | 1989 |
The effects of ruthenium red on the response of guinea-pig ileum to capsaicin.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Guinea Pigs; Ileum; In Vitro Techniques; Muscle, Smooth; Nicotine; Ruthenium; Ruthenium Red; Substance P; Tetrodotoxin | 1989 |
Modified formalin test: characteristic biphasic pain response.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bromelains; Capsaicin; Dexamethasone; Dose-Response Relationship, Drug; Formaldehyde; Indomethacin; Male; Mice; Morphine; Nerve Fibers; p-Methoxy-N-methylphenethylamine; Pain; Pain Measurement; Sciatic Nerve; Substance P; Time Factors | 1989 |
The role of competition in the refinement of the projections of sympathetic neurons to the rat eye during development.
Topics: Adrenergic Fibers; Amidines; Animals; Capsaicin; Efferent Pathways; Female; Fluorescent Dyes; Ganglia, Sympathetic; Iris; Male; Neuronal Plasticity; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P | 1989 |
Multiple mechanisms in the motor responses of the guinea-pig isolated urinary bladder to bradykinin.
Topics: Animals; Apamin; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Kallidin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Substance P; Tetrodotoxin; Thiorphan; Urinary Bladder | 1989 |
Modulation of neurotransmission in the guinea-pig vas deferens by capsaicin: involvement of calcitonin gene-related peptide and substance P.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Substance P; Synaptic Transmission; Vas Deferens | 1989 |
The autoradiographic distribution of substance P binding sites in guinea-pig vas deferens is altered by capsaicin pretreatment.
Topics: Animals; Autoradiography; Capsaicin; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Vas Deferens | 1989 |
Capsaicin-induced stimulation of polymodal nociceptors is antagonized by ruthenium red independently of extracellular calcium.
Topics: Animals; Calcium; Capsaicin; Ear; In Vitro Techniques; Nociceptors; Rabbits; Ruthenium; Ruthenium Red; Substance P | 1989 |
[Clinical significance of regulatory peptides in nasal mucosa].
Topics: Airway Obstruction; Autonomic Nervous System; Axons; Capsaicin; Humans; Nasal Mucosa; Neuropeptides; Substance P; Synaptic Transmission | 1989 |
Capsaicin evokes secretion of nasal fluid and depletes substance P and calcitonin gene-related peptide from the nasal mucosa in the rat.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Nasal Mucosa; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P | 1989 |
Topical versus systemic capsaicin desensitization: specific and unspecific effects as indicated by modification or reflex micturition in rats.
Topics: 4-Aminopyridine; Animals; Capsaicin; Injections, Intravenous; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Substance P; Urinary Bladder; Urination | 1989 |
Inhibition of carrageenan induced inflammation in the rat knee joint by substance P antagonist.
Topics: Animals; Capsaicin; Carrageenan; Hindlimb; Inflammation; Joints; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Synovitis | 1989 |
Role of substance P in immediate-type skin reactions induced by staphylococcal enterotoxin B in unsensitized monkeys.
Topics: Animals; Capsaicin; Enterotoxins; Hypersensitivity, Immediate; Immune Sera; Macaca fascicularis; Skin; Skin Tests; Staphylococcus aureus; Substance P | 1989 |
The role of substance P and calcitonin gene-related peptide in neurogenic plasma extravasation and vasodilatation in the rat.
Topics: Animals; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Hindlimb; Immune Sera; Inflammation; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Vasodilation | 1989 |
Capsaicin treatment to developing rats induces increase of noradrenaline levels in the iris without affecting the adrenergic terminal density.
Topics: Adrenergic Fibers; Animals; Capsaicin; Cell Count; Iris; Nerve Endings; Neurons, Afferent; Norepinephrine; Rats; Rats, Inbred Strains; Substance P | 1989 |
Further studies on the motor response of the human isolated urinary bladder to tachykinins, capsaicin and electrical field stimulation.
Topics: Adult; Aged; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Pyrrolidonecarboxylic Acid; Substance P; Tachykinins; Thiorphan; Urinary Bladder | 1989 |
Participation of substance P in inflammatory responses.
Topics: Animals; Capsaicin; Dactinomycin; Denervation; Dexamethasone; Edema; Hot Temperature; Inflammation; Male; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Nerves; Substance P | 1989 |
Neurotensin facilitates release of substance P in the guinea-pig inferior mesenteric ganglion.
Topics: Action Potentials; Animals; Capsaicin; Celiac Plexus; Colon; Ganglia, Spinal; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Isotonic Solutions; Male; Membrane Potentials; Neuropeptides; Neurotensin; Spinal Cord; Spinal Nerves; Substance P; Synapses | 1989 |
[Effect of epidural capsaicin on substance P in the dorsal horn in adult rats using epidural tubing].
Topics: Animals; Capsaicin; Depression, Chemical; Epidural Space; Intubation; Male; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Release of substance P by intrathecal KK-3, a newly synthesized Leu-enkephalin derivative.
Topics: Animals; Behavior, Animal; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Naloxone; Spinal Cord; Substance P | 1989 |
Captopril and capsaicin modify opioid withdrawal in the morphine-dependent rat.
Topics: Animals; Capsaicin; Captopril; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance P; Substance Withdrawal Syndrome | 1989 |
Effects of capsaicin on the circular muscle motility of the isolated guinea-pig ileum.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Substance P | 1989 |
The effects of capsaicin treatment on self-administration of amphetamine vapor in rats.
Topics: Administration, Inhalation; Amphetamine; Animals; Brain; Capsaicin; Cocaine; Disease Models, Animal; Rats; Rats, Inbred Strains; Self Administration; Substance P | 1989 |
Effects of activators and antagonists of the neuropeptides substance P and substance K on cell proliferation in planarians.
Topics: Animals; Capsaicin; Cell Division; Epidermal Growth Factor; Models, Biological; Neurokinin A; Planarians; Substance P; Turbellaria | 1989 |
Capsaicin suppresses substance P-induced joint inflammation in the rat.
Topics: Animals; Arthritis; Capsaicin; Denervation; Injections, Intra-Articular; Knee Joint; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Substance P; Synovial Membrane | 1989 |
Evidence for the involvement of endogenous substance P in the motor effects of capsaicin on the rat urinary bladder.
Topics: Acetylcholine; Animals; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder | 1985 |
The role of substance P as a neurotransmitter in the reflexes of slow time courses in the neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Neurons, Afferent; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P; Thyrotropin-Releasing Hormone; Time Factors | 1985 |
The acute and chronic effects of capsaicin on slow excitatory transmission in rat dorsal horn.
Topics: Animals; Capsaicin; In Vitro Techniques; Membrane Potentials; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors | 1985 |
Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Heart; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Nerve Tissue Proteins; Neurons, Afferent; Substance P | 1985 |
Capsaicin and regulation of respiration: interaction with central substance P mechanisms.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain; Capsaicin; Female; Glossopharyngeal Nerve; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Respiration; Substance P; Vagus Nerve | 1985 |
Nerve growth factor counteracts the neurophysiological and neurochemical effects of chronic sciatic nerve section.
Topics: Acid Phosphatase; Animals; Capsaicin; Ganglia, Spinal; Histocytochemistry; Nerve Growth Factors; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Spinal Nerves; Substance P | 1985 |
Rat trigeminal, olfactory and taste responses after capsaicin desensitization.
Topics: Animals; Capsaicin; Discrimination, Psychological; Electrophysiology; Male; Odorants; Rats; Rats, Inbred Strains; Smell; Substance P; Taste; Taste Threshold; Trigeminal Nerve | 1985 |
Mechanisms of depletion of substance P by capsaicin.
Topics: Analgesia; Animals; Capsaicin; Guinea Pigs; Nerve Growth Factors; Neurons, Afferent; Rats; Substance P; Tissue Distribution | 1985 |
Study of the contractile effect of 5-hydroxytryptamine (5-HT) in the isolated longitudinal muscle strip from guinea-pig ileum. Evidence for two distinct release mechanisms.
Topics: Animals; Atropine; Capsaicin; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Physostigmine; Serotonin; Serotonin Antagonists; Substance P; Tetrodotoxin; Tropisetron | 1985 |
Substance P immunoreactivity in the rat mammary nipple and the effects of capsaicin treatment on lactation.
Topics: Animals; Breast; Capsaicin; Female; Histocytochemistry; Immunochemistry; Lactation; Mammary Glands, Animal; Neurons; Nipples; Pregnancy; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P | 1984 |
Inhibition of compound 48/80--induced vascular protein leakage by pretreatment with capsaicin and a substance P antagonist.
Topics: Animals; Capillary Permeability; Capsaicin; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Histamine; Muscle Proteins; Muscle, Smooth, Vascular; p-Methoxy-N-methylphenethylamine; Rats; Substance P | 1984 |
Pupillary constriction by bradykinin and capsaicin: mode of action.
Topics: Animals; Bradykinin; Capsaicin; Female; In Vitro Techniques; Male; Miotics; Muscle Contraction; Pupil; Rabbits; Substance P; Tetrodotoxin | 1984 |
Cholecystokinin-like immunoreactivity in the dorsal horn of the spinal cord of the rat: a light and electron microscopic study.
Topics: Animals; Antibody Specificity; Capsaicin; Cholecystokinin; Immunoenzyme Techniques; Male; Microscopy, Electron; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1984 |
Release of substance P- and substance K-like immunoreactivities from the isolated perfused guinea-pig lung.
Topics: Animals; Capsaicin; Female; Guinea Pigs; In Vitro Techniques; Irritants; Lung; Male; Nerve Tissue Proteins; Neurokinin A; Perfusion; Radioimmunoassay; Substance P | 1984 |
Involvement of capsaicin-sensitive afferent neurones in a vagal-dependent interaction between leukotriene D4 and histamine on bronchomotor tone.
Topics: Airway Resistance; Animals; Bronchi; Capsaicin; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Indomethacin; Male; Nerve Fibers; Neurons, Afferent; SRS-A; Substance P; Vagus Nerve | 1984 |
The effects of morphine, naloxone and capsaicin on C-fiber reflex and heat evoked discharge in acute spinal cats.
Topics: Animals; Capsaicin; Cats; Decerebrate State; Evoked Potentials; Female; Hot Temperature; Male; Morphine; Naloxone; Nerve Fibers; Reflex; Spinal Nerve Roots; Substance P | 1984 |
Decrease of substance P in primary afferent neurones and impairment of neurogenic plasma extravasation by capsaicin.
Topics: Animals; Capsaicin; Denervation; Extracellular Space; Fatty Acids, Unsaturated; Neurons, Afferent; Peripheral Nerves; Rats; Skin; Substance P; Time Factors | 1980 |
Neurotoxic action of capsaicin on spinal substance P neurons.
Topics: Animals; Behavior, Animal; Capsaicin; Choline O-Acetyltransferase; Fatty Acids, Unsaturated; Glutamate Decarboxylase; Kinetics; Male; Naloxone; Neuroglia; Neurons; Neurotoxins; Rats; Receptors, Opioid; Spinal Cord; Substance P; Synapses | 1980 |
The pathophysiological effects of nitrogen mustard on the rabbit eye. II. The inhibition of the initial hypertensive phase by capsaicin and the apparent role of substance P.
Topics: Animals; Capsaicin; Denervation; Ethanol; Eye; Fatty Acids, Unsaturated; Indomethacin; Intraocular Pressure; Mechlorethamine; Pupil; Rabbits; Substance P | 1980 |
Cycloheximide-sensitive synthesis of substance P by isolated dorsal root ganglia.
Topics: Animals; Capsaicin; Cycloheximide; Ganglia, Spinal; Nerve Degeneration; Rabbits; Substance P | 1980 |
Distribution of substance P in the rat gastrointestinal tract--lack of effect of capsaicin pretreatment.
Topics: Animals; Animals, Newborn; Capsaicin; Chromatography, Gel; Digestive System; Drug Interactions; Fatty Acids, Unsaturated; Female; Ileum; Male; Rats; Substance P | 1980 |
Effects of capsaicin on nociceptive heat, pressure and chemical thresholds and on substance P levels in the rat.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Nociceptors; Rats; Sensory Receptor Cells; Skin; Spinal Cord; Substance P | 1980 |
The effects of sensory denervation on the responses of the rabbit eye to prostaglandin E1, bradykinin and substance P.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Eye; Intraocular Pressure; Male; Prostaglandins E; Rabbits; Sensory Deprivation; Substance P | 1980 |
Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo.
Topics: Afferent Pathways; Animals; Capsaicin; Cats; Injections, Spinal; Morphine; Nociceptors; Pain; Potassium; Rats; Spinal Cord; Substance P | 1980 |
Nociceptor stimulation and PGE release by capsaicin.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Calcium; Capsaicin; Ear; Fatty Acids, Unsaturated; Injections, Intra-Arterial; Nociceptors; Prostaglandins; Prostaglandins E; Rabbits; Substance P | 1980 |
Reduction of [3H]muscimol binding sites in rat dorsal spinal cord after neonatal capsaicin treatment.
Topics: Animals; Animals, Newborn; Capsaicin; Fatty Acids, Unsaturated; Ganglia, Spinal; Muscimol; Neurons; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium; Strychnine; Substance P | 1980 |
Identification by high-performance liquid chromatography of immunoreactive substance P released from isolated rat spinal cord.
Topics: Animals; Animals, Newborn; Calcium; Capsaicin; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamates; Glycine; Potassium; Radioimmunoassay; Rats; Spinal Cord; Substance P | 1980 |
The effects of microiontophoretically applied capsaicin and substance P on single neurones in the rat and cat brain.
Topics: Action Potentials; Animals; Capsaicin; Cats; Cerebellum; Fatty Acids, Unsaturated; Iontophoresis; Microinjections; Purkinje Cells; Rats; Substance P; Trigeminal Caudal Nucleus; Trigeminal Nuclei | 1980 |
Is substance P the transmitter at the first synapse of the baroreceptor reflex in rats and cats?
Topics: Animals; Blood Pressure; Capsaicin; Cats; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Medulla Oblongata; Pressoreceptors; Rats; Reflex; Substance P; Synapses | 1980 |
Effect of capsaicin pretreatment on substance P binding to synaptic vesicles.
Topics: Aging; Animals; Animals, Newborn; Binding Sites; Brain; Capsaicin; Fatty Acids, Unsaturated; Female; Male; Rats; Spinal Cord; Spinal Nerve Roots; Substance P; Synaptic Vesicles | 1980 |
Evidence suggesting a transmitter or neuromodulatory role for substance P at the first synapse of the baroreceptor reflex.
Topics: Animals; Blood Pressure; Capsaicin; Cats; Cerebral Ventricles; Female; Heart Rate; Male; Medulla Oblongata; Neurotransmitter Agents; Pressoreceptors; Rats; Substance P; Synapses | 1980 |
[Pharmacology of thin pain fibers].
Topics: Animals; Bradykinin; Capsaicin; Nerve Fibers; Nociceptors; Rabbits; Substance P; Synaptic Transmission | 1980 |
Substance P and neurotensin: discovery, isolation, chemical characterization and physiological studies.
Topics: Animals; Capsaicin; Cats; Digestive System; Ganglia, Sympathetic; Guinea Pigs; Neurotensin; Rats; Sciatic Nerve; Spinal Cord; Substance P | 1980 |
Substance P immunoreactive neurons following neonatal administration of capsaicin.
Topics: Animals; Animals, Newborn; Capsaicin; Fatty Acids, Unsaturated; Female; Male; Medulla Oblongata; Neurons; Rats; Spinal Cord; Substance P | 1981 |
Immunoreactive substance P in sympathetic ganglia: distribution and sensitivity towards capsaicin.
Topics: Animals; Brain; Capsaicin; Fatty Acids, Unsaturated; Ganglia, Sympathetic; Guinea Pigs; Immunoassay; Male; Organ Specificity; Rats; Species Specificity; Spinal Cord; Splanchnic Nerves; Substance P; Vagus Nerve | 1981 |
Inhibition of axon reflex vasodilatation by topically applied capsaicin.
Topics: Adolescent; Adult; Axons; Capsaicin; Fatty Acids, Unsaturated; Histamine; Humans; Neural Inhibition; Reflex; Skin; Substance P; Vasodilation | 1981 |
A re-evaluation of the neurochemical and antinociceptive effects of intrathecal capsaicin in the rat.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Glutamate Decarboxylase; Male; Pain; Rats; Somatostatin; Spinal Cord; Substance P | 1981 |
In vitro release of substance P from spinal cord slices by capsaicin congeners.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Ganglia, Spinal; Male; Rats; Spinal Cord; Substance P | 1981 |
Vascular and sensory responses of human skin to mild injury after topical treatment with capsaicin.
Topics: Administration, Topical; Axons; Capsaicin; Differential Threshold; Fatty Acids, Unsaturated; Humans; Pain; Reflex; Sensation; Skin; Substance P; Vasodilation | 1981 |
Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on nociceptive behavior and cardiovascular regulation.
Topics: Angiotensin II; Animals; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hemodynamics; Hypertension; Male; Nociceptors; Norepinephrine; Rats; Rats, Inbred Strains; Substance P | 1981 |
Time course of capsaicin-induced functional impairments in comparison with changes in neuronal substance P content.
Topics: Animals; Capsaicin; Cornea; Fatty Acids, Unsaturated; Female; Ganglia, Spinal; Injections, Subcutaneous; Male; Mustard Plant; Neurons; Plant Extracts; Plant Oils; Plants, Medicinal; Rats; Substance P; Time Factors | 1981 |
Characterization in guinea pigs of the sensory effects of the putative substance P neurotoxin capsaicin.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Guinea Pigs; Male; Morphine; Pain; Sensory Receptor Cells; Somatostatin; Substance P | 1981 |
Effect of capsaicin pretreatment on capsaicin-evoked release of immunoreactive somatostatin and substance P from primary sensory neurons.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; In Vitro Techniques; Male; Motor Neurons; Neurons; Potassium; Rats; Somatostatin; Spinal Cord; Substance P | 1981 |
Degeneration of axons in the ureteric and duodenal nerve plexuses of the adult rat following in vivo treatment with capsaicin.
Topics: Afferent Pathways; Animals; Axons; Capsaicin; Duodenum; Fatty Acids, Unsaturated; Microscopy, Electron; Myenteric Plexus; Nerve Degeneration; Nociceptors; Rats; Substance P; Synaptic Vesicles; Ureter | 1981 |
Effect of capsaicin administration to neonatal rats on the substance P content of discrete CNS regions.
Topics: Animals; Animals, Newborn; Brain; Capsaicin; Fatty Acids, Unsaturated; Male; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Tissue Distribution | 1981 |
Effects of neonatal administration of capsaicin on nociceptive thresholds in the mouse and rat.
Topics: Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Fatty Acids, Unsaturated; Female; Male; Maximum Allowable Concentration; Mice; Nerve Fibers; Nociceptors; Rats; Substance P | 1981 |
Intranigral injection of capsaicin enhances motor activity and depletes nigral 5-hydroxytryptamine but not substance P.
Topics: Animals; Brain; Capsaicin; Dimethyl Sulfoxide; Dopamine; Fatty Acids, Unsaturated; Female; Motor Activity; Rats; Serotonin; Substance P; Substantia Nigra | 1981 |
Similarities in development of substance P and somatostatin in peripheral sensory neurons: effects of capsaicin and nerve growth factor.
Topics: Animals; Animals, Newborn; Capsaicin; Ganglia, Spinal; Nerve Growth Factors; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P | 1981 |
Ocular responses to antidromic trigeminal stimulation, intracameral prostaglandin E1 and E2, capsaicin and substance P.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Female; Indomethacin; Intraocular Pressure; Male; Miotics; Neural Conduction; Prostaglandins E; Prostaglandins F; Pupil; Rabbits; Substance P; Tetrodotoxin; Trigeminal Nerve; Uveitis | 1981 |
Capsaicin and potassium evoked substance P release from the nucleus tractus solitarius and spinal trigeminal nucleus in vitro.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Male; Medulla Oblongata; Potassium; Rats; Rats, Inbred Strains; Substance P; Trigeminal Nucleus, Spinal | 1981 |
Differential effects of capsaicin on the content of somatostatin, substance P, and neurotensin in the nervous system of the rat.
Topics: Analgesia; Animals; Animals, Newborn; Capsaicin; Fatty Acids, Unsaturated; Male; Nervous System; Neurotensin; Rats; Somatostatin; Substance P; Time Factors | 1981 |
Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Capsaicin; Fatty Acids, Unsaturated; Fluorides; Male; Nerve Degeneration; Nerve Fibers; Neurons, Afferent; Peptides; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P | 1981 |
Immunohistochemical studies on the effect of capsaicin on spinal and medullary peptide and monoamine neurons using antisera to substance P, gastrin/CCK, somatostatin, VIP, enkephalin, neurotensin and 5-hydroxytryptamine.
Topics: Animals; Capsaicin; Cholecystokinin; Enkephalins; Fatty Acids, Unsaturated; Fluorescent Antibody Technique; Ganglia; Gastrins; Histocytochemistry; Neurons; Neurotensin; Peptides; Rats; Serotonin; Somatostatin; Spinal Cord; Substance P; Trigeminal Nuclei; Vasoactive Intestinal Peptide | 1981 |
Sensory and motor functions of spinal cord substance P.
Topics: Animals; Capsaicin; Mice; Motor Activity; Pain; Receptors, Cell Surface; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Skin; Spinal Cord; Substance P | 1981 |
Effect of prolonged and neonatal capsaicin treatments on the substance P immunoreactive nerves in the rabbit eye and spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Eye; Fatty Acids, Unsaturated; Fluorescent Antibody Technique; Iris; Miotics; Rats; Spinal Cord; Substance P | 1981 |
Substance P-like immunoreactivity in the intramural nerve plexuses of the guinea-pig ureter: a light and electron microscopical study.
Topics: Animals; Axons; Capsaicin; Fluorescent Antibody Technique; Guinea Pigs; Immunoenzyme Techniques; Microscopy, Electron; Nerve Endings; Substance P; Ureter | 1981 |
Thermal analgesia and substance P depletion induced by capsaicin in guinea-pigs.
Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Ganglia, Spinal; Guinea Pigs; Male; Nociceptors; Sensory Thresholds; Spinal Cord; Substance P; Thermosensing | 1981 |
Depletion by capsaicin of substance P-immunoreactivity and acetylcholinesterase activity from nerve fibres in the guinea-pig heart.
Topics: Acetylcholinesterase; Animals; Capsaicin; Fatty Acids, Unsaturated; Female; Guinea Pigs; Heart; Hydroxydopamines; Male; Nerve Fibers; Substance P | 1981 |
Effects of capsaicin applied locally to adult peripheral nerve. II. Anatomy and enzyme and peptide chemistry of peripheral nerve and spinal cord.
Topics: Acid Phosphatase; Animals; Capsaicin; Cholecystokinin; Fatty Acids, Unsaturated; Female; Male; Nerve Fibers, Myelinated; Peptides; Peripheral Nerves; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Substance P | 1981 |
Depletion of primary afferent substance P by capsaicin and dihydrocapsaicin without altered thermal sensitivity in rats.
Topics: Animals; Animals, Newborn; Capsaicin; Fatty Acids, Unsaturated; Female; Ganglia, Spinal; Male; Movement; Neurons, Afferent; Rats; Rats, Inbred Strains; Reaction Time; Spinal Cord; Spinal Nerve Roots; Substance P; Tail; Thermosensing | 1982 |
Indirect evidence for the inhibition of enteric substance P neurones by opiate agonists but not by capsaicin.
Topics: Animals; Capsaicin; Electric Stimulation; Fatty Acids, Unsaturated; Female; Guinea Pigs; In Vitro Techniques; Intestines; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotics; Neurons; Substance P; Synaptic Transmission | 1982 |
Capsaicin does not change tissue levels of glutamic acid, its uptake, or release in the rat spinal cord.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Glutamates; Glutamic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptosomes | 1982 |
Noncholinergic, nonadrenergic contraction and substance P in rabbit iris sphincter muscle.
Topics: Acetylcholine; Animals; Baclofen; Capsaicin; Cold Temperature; Electric Stimulation; Female; In Vitro Techniques; Iris; Male; Muscle Contraction; Rabbits; Reserpine; Substance P; Sympathectomy | 1981 |
Intraventricular capsaicin: alterations in analgesic responsivity without depletion of substance P.
Topics: Animals; Brain; Capsaicin; Fatty Acids, Unsaturated; Injections, Intraventricular; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains; Sensory Thresholds; Spinal Cord; Substance P; Synaptic Transmission | 1982 |
Substance P-immunoreactive peripheral branches of sensory neurons innervate guinea pig sympathetic neurons.
Topics: Animals; Capsaicin; Ganglia, Sympathetic; Guinea Pigs; Nerve Endings; Neural Pathways; Substance P; Sympathetic Nervous System; Synapses | 1982 |
Substance P-like immunoreactivity in nerves associated with the vascular system of guinea-pigs.
Topics: Animals; Blood Vessels; Capsaicin; Female; Fluorescent Antibody Technique; Guinea Pigs; Hydroxydopamines; Male; Nerve Endings; Nerve Fibers; Neurons, Afferent; Oxidopamine; Sensation; Substance P | 1982 |
Capsaicin applied to peripheral nerve inhibits axoplasmic transport of substance P and somatostatin.
Topics: Acetylcholinesterase; Acid Phosphatase; Animals; Axonal Transport; Capsaicin; Cats; Colchicine; Fatty Acids, Unsaturated; Guinea Pigs; Neural Conduction; Norepinephrine; Peripheral Nerves; Rabbits; Rats; Rats, Inbred Strains; Sciatic Nerve; Somatostatin; Spinal Cord; Substance P | 1982 |
Sensory neural mechanisms in contraction of the isolated sphincter pupillae: the role for substance P and the effects of sensory denervation on the responses to miotics.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Iris; Male; Miotics; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Rabbits; Substance P; Trigeminal Nerve | 1982 |
Substance P in the mouse cornea: effects of chemical and surgical denervation.
Topics: Animals; Animals, Newborn; Capsaicin; Cornea; Mice; Neurons; Reflex; Substance P; Sympathectomy; Sympathectomy, Chemical | 1982 |
Effects of substance P on the isolated iris sphincter muscle of the albino rabbit.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Iris; Male; Muscle, Smooth; Rabbits; Substance P; Tetrodotoxin | 1982 |
Evidence that the contractile response of the guinea-pig ileum to capsaicin is due to substance P release.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Fatty Acids, Unsaturated; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Physostigmine; Substance P | 1982 |
The effects of capsaicin pre-treatment on the responses of single neurones to sensory stimuli in the trigeminal nucleus caudalis of the rat: evidence against a role for substance P as the neurotransmitter serving thermal nociception.
Topics: Animals; Capsaicin; Evoked Potentials, Somatosensory; Fatty Acids, Unsaturated; Hot Temperature; Mechanoreceptors; Muridae; Neurons; Nociceptors; Substance P; Synaptic Transmission; Thermoreceptors; Trigeminal Caudal Nucleus; Trigeminal Nucleus, Spinal | 1982 |
Capsaicinoid-induced local and systemic antinociception without substance P depletion.
Topics: Afferent Pathways; Animals; Capsaicin; Corpus Striatum; Fatty Acids, Unsaturated; Ganglia, Spinal; Guinea Pigs; Hypothalamus; Nociceptors; Skin; Spinal Cord; Substance P | 1982 |
Substance P in the cerebral vasculature: depletion by capsaicin suggests a sensory role.
Topics: Animals; Capsaicin; Cats; Cerebral Arteries; Fatty Acids, Unsaturated; Female; Guinea Pigs; Male; Neurons, Afferent; Rabbits; Somatostatin; Substance P | 1982 |
Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on substance P contents of peripheral and central nervous system tissues.
Topics: Adrenal Medulla; Animals; Brain Chemistry; Capsaicin; Fatty Acids, Unsaturated; Ganglia, Sympathetic; Hypertension; Male; Nervous System; Rats; Rats, Inbred Strains; Substance P | 1982 |
Manifestations of gut opiate withdrawal contracture and its blockade by capsaicin.
Topics: Animals; Capsaicin; Digestive System; Electric Stimulation; Fatty Acids, Unsaturated; Guinea Pigs; Humans; Male; Muscle Contraction; Myenteric Plexus; Naloxone; Scopolamine; Serotonin; Serotonin Antagonists; Substance P; Substance Withdrawal Syndrome | 1982 |
Capsaicin and nociception in the rat and mouse. Possible role of substance P.
Topics: Animals; Behavior, Animal; Capsaicin; Eye; Fatty Acids, Unsaturated; Female; Hindlimb; Injections, Spinal; Male; Mice; Nociceptors; Pain; Rats; Rats, Inbred Strains; Species Specificity; Substance P; Thermoreceptors | 1982 |
Distribution of capsaicin-sensitive nerve fibres containing immunoreactive substance P in cutaneous and visceral tissues of the rat.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Heart; Hepatic Duct, Common; Lung; Mesentery; Mouth Mucosa; Nerve Degeneration; Nerve Fibers; Rats; Rats, Inbred Strains; Skin; Stellate Ganglion; Substance P; Trachea; Ureter; Urinary Bladder | 1982 |
Influence of neonatally administered capsaicin on baroreceptor and chemoreceptor reflexes in the adult rat.
Topics: Animals; Animals, Newborn; Blood Pressure; Capsaicin; Chemoreceptor Cells; Fatty Acids, Unsaturated; Nerve Fibers; Norepinephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Respiration; Sodium Cyanide; Substance P | 1982 |
Regulation of substance P by nerve growth factor: disruption by capsaicin.
Topics: Animals; Axonal Transport; Capsaicin; Efferent Pathways; Fatty Acids, Unsaturated; Ganglia, Spinal; Guinea Pigs; Kinetics; Mice; Nerve Growth Factors; Substance P | 1982 |
Trigeminal nerve: the possible origin of substance p-nergic response in isolated rabbit iris sphincter muscle.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Enkephalins; Female; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscles; Rabbits; Somatostatin; Substance P; Trigeminal Nerve; Vasoactive Intestinal Peptide | 1982 |
Substance P as an excitatory transmitter of primary afferent neurons in guinea-pig sympathetic ganglia.
Topics: Adrenergic Fibers; Afferent Pathways; Animals; Autonomic Fibers, Preganglionic; Axonal Transport; Capsaicin; Cholinergic Fibers; Evoked Potentials; Ganglia, Spinal; Ganglia, Sympathetic; Guinea Pigs; Male; Neurons; Potassium; Radioimmunoassay; Substance P; Synapses; Synaptic Transmission | 1982 |
Characterization of substance P-like immunoreactivity in peripheral sensory nerves and enteric nerves by high pressure liquid chromatography and radioimmunoassay.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Guinea Pigs; Heart Atria; Mesenteric Arteries; Myenteric Plexus; Peripheral Nerves; Radioimmunoassay; Substance P; Ureter | 1982 |
Dihydrocapsaicin-induced hypothermia and substance P depletion.
Topics: Animals; Body Temperature Regulation; Capsaicin; Fatty Acids, Unsaturated; Female; Ganglia, Spinal; Hypothermia; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1982 |
Baroreceptor reflexes in conscious guinea-pigs are unaffected by depletion of cardiovascular substance P nerves.
Topics: Animals; Blood Pressure; Capsaicin; Cardiovascular System; Carotid Arteries; Carotid Sinus; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Guinea Pigs; Heart Rate; Pericardium; Pressoreceptors; Reflex; Substance P | 1982 |
Substance P reduces tail-flick latency: implications for chronic pain syndromes.
Topics: Analgesia; Animals; Capsaicin; Dose-Response Relationship, Drug; Hot Temperature; Male; Pain; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Cell Surface; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1982 |
Capsaicin-sensitive vagal neurons involved in control of vascular permeability in rat trachea.
Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Fatty Acids, Unsaturated; Hexamethonium Compounds; Neurons, Afferent; Rats; Substance P; Trachea; Vagus Nerve | 1982 |
The origin of substance P in the rat submandibular gland and its major duct.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Fluorescent Antibody Technique; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Submandibular Gland; Substance P | 1982 |
Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Male; Myelin Sheath; Neurons; Rats; Rats, Inbred Strains; Sciatic Nerve; Somatostatin; Spinal Cord; Substance P | 1983 |
Evidence that the contractile response of the guinea-pig ileum to capsaicin is due to release of substance P.
Topics: Animals; Atropine; Capsaicin; Endorphins; Fatty Acids, Unsaturated; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Naloxone; Substance P | 1982 |
Nerve growth factor antagonizes the neurotoxic action of capsaicin on primary sensory neurones.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Ganglia, Spinal; Male; Mice; Nerve Growth Factors; Neurons; Substance P | 1983 |
Effects of capsaicin on inflammation and on the substance P content of nervous tissues in rats with adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Capsaicin; Fatty Acids, Unsaturated; Inflammation; Kinetics; Male; Mycobacterium; Nervous System; Rats; Rats, Inbred Strains; Substance P | 1983 |
Effect of intrathecal capsaicin analogues on the immunofluorescence of peptides and serotonin in the dorsal horn in rats.
Topics: Alkaloids; Animals; Benzodioxoles; Capsaicin; Cholecystokinin; Enkephalin, Methionine; Fatty Acids, Unsaturated; Ganglia, Spinal; Kainic Acid; Male; Microscopy, Fluorescence; Nociceptors; Peptides; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Inbred Strains; Sensory Thresholds; Serotonin; Somatostatin; Substance P | 1983 |
Some rat sensory neurons in culture express characteristics of differentiated pain sensory cells.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Cell Differentiation; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Neurons; Pain; Prostaglandins E; Rats; Substance P; Trigeminal Nerve | 1983 |
Pharmacological studies on the application, disposition, and release of neurotensin in the spinal cord.
Topics: Animals; Capsaicin; Cats; Histocytochemistry; Kainic Acid; Neurotensin; Nociceptors; Pain; Radioimmunoassay; Reaction Time; Spinal Cord; Spinal Nerve Roots; Substance P; Tissue Distribution | 1982 |
Inflammatory peptide in spinal cord: evidence that the mediator of antidromic vasodilatation is not substance P.
Topics: Afferent Pathways; Animals; Animals, Newborn; Biological Assay; Capsaicin; Cattle; Edema; Guinea Pigs; Ileum; Peptides; Rats; Spinal Cord; Substance P; Vasodilation | 1980 |
The effects of prenatal capsaicin on the distribution of substance P in developing primary afferent neurons.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Female; Maternal-Fetal Exchange; Mice; Neurons, Afferent; Pregnancy; Prenatal Exposure Delayed Effects; Spinal Cord; Substance P | 1983 |
A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig.
Topics: Amino Acid Sequence; Animals; Bronchi; Bronchial Spasm; Capillary Permeability; Capsaicin; Female; Guinea Pigs; Male; Pulmonary Circulation; Substance P; Trachea; Vagus Nerve | 1983 |
Bronchial smooth muscle contraction induced by stimulation of capsaicin-sensitive sensory neurons.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Bronchi; Capsaicin; Electric Stimulation; Fatty Acids, Unsaturated; Guinea Pigs; Heart Rate; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Substance P; Trachea; Vagus Nerve | 1982 |
Substance P mediates atropine-sensitive response of guinea-pig ileum to serotonin.
Topics: Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Nicotine; Serotonin; Substance P | 1983 |
Hot peppers and substance P.
Topics: Capsaicin; Capsicum; Fatty Acids, Unsaturated; Humans; Nociceptors; Plant Extracts; Plants, Medicinal; Substance P | 1983 |
Substance P neurones in medullary baroreflex areas and baroreflex function of capsaicin-treated rats. Comparison with other primary afferent systems.
Topics: Afferent Pathways; Animals; Capsaicin; Fatty Acids, Unsaturated; Female; Fluorescent Antibody Technique; Immunoenzyme Techniques; Male; Medulla Oblongata; Neurons; Nociceptors; Pressoreceptors; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1983 |
In the eye (D-Pro2, D-Trp7,9)-SP is a substance P agonist, which modifies the responses to substance P, prostaglandin E1 and antidromic trigeminal nerve stimulation.
Topics: Alprostadil; Animals; Capsaicin; Electric Stimulation; Eye; Female; Male; Prostaglandins E; Pupil; Rabbits; Substance P; Trigeminal Nerve | 1983 |
Release of histamine by neuropeptides from the perfused rat hindquarter.
Topics: Animals; Animals, Newborn; Capsaicin; Hindlimb; Histamine Release; In Vitro Techniques; Male; Mast Cells; Perfusion; Rats; Rats, Inbred Strains; Serotonin; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1983 |
Reflex fall in blood pressure mediated by capsaicin-sensitive afferent fibers of the rat splanchnic nerve.
Topics: Animals; Blood Pressure; Capsaicin; Fatty Acids, Unsaturated; Female; Male; Neurons, Afferent; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Splanchnic Nerves; Substance P | 1983 |
Unmyelinated axon subpopulations in the rat peripheral nervous system.
Topics: Animals; Axons; Capsaicin; Female; Ganglia, Spinal; Male; Muscles; Myelin Sheath; Rats; Rats, Inbred Strains; Sciatic Nerve; Somatostatin; Spinal Nerves; Substance P; Sural Nerve | 1983 |
Histamine release and vascular changes induced by neuropeptides.
Topics: Amino Acid Sequence; Animals; Capsaicin; Eledoisin; Histamine Release; Humans; Mast Cells; Neurotensin; Peptide Fragments; Peptides; Rats; Skin; Substance P; Vasodilation | 1983 |
Concurrent measurement of substance P and serotonin in spinal superfusates: failure of capsaicin and p-chloroamphetamine to co-release.
Topics: Amphetamines; Animals; Capsaicin; Fatty Acids, Unsaturated; Male; p-Chloroamphetamine; Perfusion; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P | 1983 |
Structure-activity relationships for some substance P-related peptides that cause wheal and flare reactions in human skin.
Topics: Adenosine Triphosphate; Adult; Autacoids; Capillary Permeability; Capsaicin; Chlorpheniramine; Dose-Response Relationship, Drug; Eledoisin; Histamine; Humans; Intercellular Signaling Peptides and Proteins; Middle Aged; Peptides; Physalaemin; Skin; Structure-Activity Relationship; Substance P; Time Factors; Vasodilation | 1983 |
Ocular responses evoked by capsaicin and prostaglandin E2 are inhibited by a substance P antagonist.
Topics: Animals; Aqueous Humor; Capsaicin; Dinoprostone; Fatty Acids, Unsaturated; Prostaglandins E; Pupil; Rabbits; Substance P; Tetrodotoxin | 1983 |
The termination of primary afferents within the rat dorsal horn: evidence for rearrangement following capsaicin treatment.
Topics: Acid Phosphatase; Animals; Capsaicin; Fatty Acids, Unsaturated; Neurons, Afferent; Peripheral Nerves; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Terminology as Topic | 1983 |
Capsaicin causes release of a substance P-like peptide in guinea-pig inferior mesenteric ganglia.
Topics: Action Potentials; Animals; Calcium; Capsaicin; Fatty Acids, Unsaturated; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Membrane Potentials; Neurons; Peptides; Rana catesbeiana; Substance P; Time Factors | 1983 |
[Acute effects of intrathecal capsaicin and substance P on nociceptive thresholds in rats].
Topics: Animals; Capsaicin; Electric Stimulation; Hot Temperature; Injections, Spinal; Male; Nociceptors; Rats; Sensory Thresholds; Substance P | 1983 |
Characterization of the peptide and sensory neurotoxic effects of capsaicin in the guinea pig.
Topics: Animals; Capsaicin; Cholecystokinin; Dose-Response Relationship, Drug; Ganglia, Spinal; Guinea Pigs; Morphine; Nerve Tissue Proteins; Nervous System Diseases; Neurons, Afferent; Nociceptors; Peripheral Nerves; Somatostatin; Spinal Cord; Substance P; Vasoactive Intestinal Peptide | 1983 |
In vitro release of immunoreactive substance P from putative afferent nerve endings in bovine pia arachnoid.
Topics: Animals; Arachnoid; Calcium; Capsaicin; Cattle; Cerebral Arteries; In Vitro Techniques; Neurons, Afferent; Pia Mater; Potassium; Substance P; Trigeminal Nerve | 1983 |
Inhibition of smooth muscle contractions induced by capsaicin and electrical transmural stimulation by a substance P antagonist.
Topics: Animals; Capsaicin; Electric Stimulation; Guinea Pigs; Ileum; Iris; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Cell Surface; Receptors, Neurokinin-1; Substance P | 1983 |
Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: neurochemical effects in the spinal cord.
Topics: Animals; Capsaicin; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P | 1983 |
Substance P is a functional neurotransmitter in the rat parotid gland.
Topics: Amylases; Animals; Atropine; Capsaicin; Electric Conductivity; Electric Stimulation; In Vitro Techniques; Male; Membrane Potentials; Parotid Gland; Phentolamine; Propranolol; Rats; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1983 |
Sensory substance P-innervation of the urinary bladder: possible site of action of capsaicin in causing urine retention in rats.
Topics: Animals; Capsaicin; Female; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Urinary Bladder; Urination | 1983 |
Capsaicin-induced substance P release and sensory control of vascular permeability in the guinea-pig ureter.
Topics: Animals; Capillary Permeability; Capsaicin; Electric Stimulation; Ganglia, Sympathetic; Guinea Pigs; Histocytochemistry; Immunologic Techniques; Neurons, Afferent; Substance P; Ureter | 1983 |
Capsaicin decreases B-endorphin hypothalamic concentrations in the rat.
Topics: Animals; Animals, Newborn; beta-Endorphin; Capsaicin; Endorphins; Enkephalin, Methionine; Hypothalamus; Male; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Time Factors | 1983 |
Substance P and capsaicin-induced contraction of human bronchi.
Topics: Acetylcholine; Aged; Animals; Atropine; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Humans; Middle Aged; Muscle Contraction; Muscle, Smooth; Substance P; Tetrodotoxin | 1983 |
Effects of antidromic trigeminal nerve stimulation in relation to parasympathetic vasodilation in cat nasal mucosa.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Cats; Electric Stimulation; Hexamethonium Compounds; Nasal Mucosa; Parasympathetic Nervous System; Regional Blood Flow; Substance P; Trigeminal Nerve; Vasoactive Intestinal Peptide; Vasodilation | 1983 |
Vascular protein linkage in various tissue induced by substance P, capsaicin, bradykinin, serotonin, histamine and by antigen challenge.
Topics: Animals; Antigens; Blood Proteins; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Substance P | 1983 |
Effects and distribution of vagal capsaicin-sensitive substance P neurons with special reference to the trachea and lungs.
Topics: Animals; Capsaicin; Chromatography, Gel; Esophagus; Female; Guinea Pigs; Heart; Lung; Male; Myocardium; Neurons; Radioimmunoassay; Respiration; Substance P; Sympathectomy; Trachea; Vagus Nerve; Vascular Resistance | 1983 |
Slow excitatory transmission in rat dorsal horn: possible mediation by peptides.
Topics: Animals; Capsaicin; Cholecystokinin; Electric Conductivity; Neurons; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synapses; Tetrodotoxin; Vasoactive Intestinal Peptide | 1984 |
Capsaicin-induced reflex fall in rat blood pressure is mediated by afferent substance P-containing neurones via a reflex centre in the brain stem.
Topics: Animals; Blood Pressure; Brain Stem; Capsaicin; Decerebrate State; Injections, Intra-Arterial; Injections, Spinal; Male; Neurons, Afferent; Rats; Reflex; Substance P | 1983 |
Cigarette smoke-induced airway oedema due to activation of capsaicin-sensitive vagal afferents and substance P release.
Topics: Afferent Pathways; Animals; Capillary Permeability; Capsaicin; Edema; Male; Microscopy, Fluorescence; Rats; Rats, Inbred Strains; Respiratory System; Respiratory Tract Diseases; Smoking; Substance P; Synaptic Transmission; Vagus Nerve | 1983 |
Pharmacology of the primary nociceptive neuron.
Topics: Analgesics; Capsaicin; Humans; Neurons; Nociceptors; Prostaglandin Antagonists; Stimulation, Chemical; Substance P | 1984 |
Axonal transport of opiate receptors in capsaicin-sensitive neurones.
Topics: Animals; Axonal Transport; Capsaicin; Fentanyl; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance P; Vagus Nerve | 1984 |
[Effects of bradykinin and capsaicin on substance P-induced reactions in the iris sphincter muscle].
Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; In Vitro Techniques; Iris; Muscle Contraction; Rabbits; Substance P | 1983 |
Substance P-immunoreactive sensory nerves in the lower respiratory tract of various mammals including man.
Topics: Adult; Animals; Bronchi; Capsaicin; Cats; Denervation; Fluorescent Antibody Technique; Ganglia; Guinea Pigs; Humans; Radioimmunoassay; Rats; Respiratory System; Species Specificity; Substance P; Vinblastine | 1984 |
Studies of the axoplasmic transport of somatostatin in the vagus nerve of the rat.
Topics: Animals; Axonal Transport; Capsaicin; Colchicine; Guanethidine; Male; Nodose Ganglion; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Sympathectomy, Chemical; Vagus Nerve | 1984 |
Capsaicin-induced depletion of substance P-like immunoreactivity in guinea pig sympathetic ganglia.
Topics: Animals; Bombesin; Capsaicin; Cholecystokinin; Enkephalin, Methionine; Fluorescent Antibody Technique; Ganglia, Sympathetic; Guinea Pigs; Male; Substance P; Vasoactive Intestinal Peptide | 1983 |
Enkephalin-like immunofluorescence in nerves of the rat iris following systemic capsaicin injection.
Topics: Animals; Capsaicin; Enkephalins; Female; Fluorescent Antibody Technique; Iris; Nerve Fibers; Rats; Rats, Inbred Strains; Substance P | 1983 |
Substance P microinjections into the nucleus tractus solitarius elicit a pressor response in capsaicin-treated rats.
Topics: Afferent Pathways; Animals; Arginine Vasopressin; Blood Pressure; Capsaicin; Cardiovascular System; Female; Heart Rate; Male; Medulla Oblongata; Nerve Degeneration; Pressoreceptors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1983 |
Vascular permeability changes and smooth muscle contraction in relation to capsaicin-sensitive substance P afferents in the guinea-pig.
Topics: Animals; Autonomic Nervous System; Capillary Permeability; Capsaicin; Electric Stimulation; Evans Blue; Female; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Sensory Receptor Cells; Substance P | 1984 |
Capsaicin-induced stimulation of the guinea-pig atrium. Involvement of a novel sensory transmitter or a direct action on myocytes?
Topics: Adenosine Triphosphate; Animals; Capsaicin; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardium; Neurotransmitter Agents; Norepinephrine; Nucleotides; Substance P | 1984 |
Effects of the substance P antagonist, (D-Arg1, D-Pro2, D-Trp7,9, Leu11)-SP on the miotic response to substance P, antidromic trigeminal nerve stimulation, capsaicin, prostaglandin E1, compound 48/80 and histamine.
Topics: Alprostadil; Animals; Capsaicin; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Prostaglandins E; Pupil; Rabbits; Substance P; Tetrodotoxin; Trigeminal Nerve | 1984 |
Comparison of nonivamide and capsaicin with regard to their pharmacokinetics and effects on sensory neurons.
Topics: Animals; Behavior, Animal; Blood Pressure; Capsaicin; Eye; Female; Hydroxybenzoates; Kinetics; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Vanillic Acid | 1984 |
Characterization of the stimulus-induced release of immunoreactive substance P from the myenteric plexus of the guinea-pig small intestine.
Topics: Animals; Calcium; Capsaicin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Electric Stimulation; Female; Guinea Pigs; Male; Myenteric Plexus; Naloxone; Neurotransmitter Agents; Potassium; Substance P | 1984 |
The development of responsiveness to substance P and glutamate in the spinal motoneurons of rat fetuses.
Topics: Animals; Capsaicin; Cell Differentiation; Evoked Potentials; Female; Gestational Age; Glutamates; Glutamic Acid; Motor Neurons; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptic Transmission | 1984 |
Respiratory effects of intrathecal capsaicin in arthritic and non-arthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Body Weight; Capsaicin; Injections, Spinal; Male; Pain; Rats; Rats, Inbred Strains; Respiration; Substance P | 1984 |
Neonatal capsaicin treatment prevents insulin-stress-induced adrenal catecholamine secretion in vivo: possible involvement of sensory nerves containing substance P.
Topics: Adrenal Glands; Animals; Animals, Newborn; Capsaicin; Catecholamines; Female; Insulin; Male; Neurons, Afferent; Rats; Rats, Inbred BUF; Stress, Physiological; Substance P | 1984 |
Substance P in sensory nerve fibres contributes to the development of oedema in the rat hind paw after thermal injury.
Topics: Animals; Blood Proteins; Burns; Capsaicin; Edema; Evans Blue; Female; Hindlimb; Male; Nerve Tissue Proteins; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Temperature; Time Factors | 1984 |
Conduction-block induced by capsaicin in crayfish giant axon.
Topics: Action Potentials; Animals; Astacoidea; Axons; Capsaicin; In Vitro Techniques; Ion Channels; Membrane Potentials; Nerve Block; Neural Conduction; Sodium; Substance P | 1984 |
A slow EPSP in mammalian inferior mesenteric ganglion persists after in vivo capsaicin.
Topics: Animals; Capsaicin; Ganglia, Spinal; Ganglia, Sympathetic; Guinea Pigs; Male; Membrane Potentials; Neurons, Afferent; Substance P; Synapses; Synaptic Transmission | 1984 |
Intestinal peristalsis associated with release of immunoreactive substance P.
Topics: Animals; Capsaicin; Dimethylphenylpiperazinium Iodide; Female; Gastrointestinal Motility; Guinea Pigs; Intestines; Male; Neurotransmitter Agents; Potassium; Reflex; Substance P; Synaptic Transmission | 1984 |
Capsaicin and bradykinin-induced substance P-ergic responses in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Female; Guanethidine; Iris; Male; Muscle Contraction; Rabbits; Substance P; Tachyphylaxis | 1984 |
Comparison of capsaicin and substance P induced cyclic AMP accumulation in spinal cord tissue slices.
Topics: Animals; Calcium; Capsaicin; Cyclic AMP; Female; Guinea Pigs; Hypothalamus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Substantia Nigra; Time Factors | 1984 |
Immunoreactive substance P in the tubero-hypophyseal system of the rat: selective decrease in the neural lobe after dehydration and sodium loading.
Topics: Animals; Capsaicin; Dehydration; Hypothalamo-Hypophyseal System; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Sodium; Substance P; Tissue Distribution | 1984 |
Action of intrathecal capsaicin and its structural analogues on the content and release of spinal substance P: selectivity of action and relationship to analgesia.
Topics: Animals; Capsaicin; Cholecystokinin; Homovanillic Acid; Injections, Spinal; Male; Pain; Phenylacetates; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Tachyphylaxis; Vasoactive Intestinal Peptide | 1984 |
Regional distribution of kassinin-like immunoreactivity in rat central and peripheral tissues and the effect of capsaicin.
Topics: Animals; Animals, Newborn; Capsaicin; Central Nervous System; Female; Kassinin; Male; Nervous System; Oligopeptides; Peripheral Nerves; Rats; Rats, Inbred Strains; Substance P | 1984 |
Is substance P necessary for corneal nociception?
Topics: Anesthetics, Local; Animals; Capsaicin; Cornea; Histocytochemistry; Immunochemistry; Nociceptors; Procaine; Rabbits; Substance P; Tetrodotoxin | 1984 |
Sensory substance P innervation of the stomach and pancreas. Demonstration of capsaicin-sensitive sensory neurons in the rat by combined immunohistochemistry and retrograde tracing.
Topics: Animals; Benzofurans; Capsaicin; Female; Fluorescent Antibody Technique; Fluorescent Dyes; Ganglia, Parasympathetic; Ganglia, Spinal; Ganglia, Sympathetic; Histocytochemistry; Male; Neurons, Afferent; Pancreas; Rats; Rats, Inbred Strains; Stomach; Substance P | 1984 |
Inhibition of cigarette smoke-induced oedema in the nasal mucosa by capsaicin pretreatment and a substance P antagonist.
Topics: Animals; Blood Pressure; Capillary Permeability; Capsaicin; Carbon Monoxide; Edema; Histamine Antagonists; Male; Nasal Mucosa; Nicotine; Rats; Rats, Inbred Strains; Smoking; Substance P | 1984 |
Protective reflexes and vascular effects in the nasal mucosa elicited by activation of capsaicin-sensitive substance P-immunoreactive trigeminal neurons.
Topics: Animals; Capillary Permeability; Capsaicin; Cats; Guinea Pigs; Humans; Nasal Mucosa; Neurons; Neurons, Afferent; Nicotine; Parasympathetic Nervous System; Rats; Receptors, Cell Surface; Receptors, Neurokinin-1; Reflex; Regional Blood Flow; Smoking; Sneezing; Species Specificity; Substance P; Trigeminal Nerve | 1984 |
The effects of topical capsaicin on rat urinary bladder motility in vivo.
Topics: Acetylcholine; Administration, Topical; Animals; Atropine; Capsaicin; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder | 1984 |
The depolarising action of capsaicin on rat isolated sciatic nerve.
Topics: Afferent Pathways; Animals; Capsaicin; Membrane Potentials; Nociceptors; Rats; Sciatic Nerve; Structure-Activity Relationship; Substance P | 1984 |
Substance P in primary afferent neurons of the female rat reproductive system.
Topics: Animals; Animals, Newborn; Capsaicin; Castration; Estrus; Female; Genitalia, Female; Neurons, Afferent; Pregnancy; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P | 1984 |
Time course of effect of capsaicin on ultrastructure and histochemistry of substance P-immunoreactive nerves associated with the cardiovascular system of the guinea-pig.
Topics: Animals; Capsaicin; Cardiovascular System; Female; Fluorescent Antibody Technique; Guinea Pigs; Male; Microscopy, Electron; Peripheral Nerves; Radioimmunoassay; Substance P; Time Factors | 1984 |
Factors affecting massive postmortem bronchoconstriction in guinea pig lungs.
Topics: Animals; Bronchi; Calcium; Capsaicin; Chromones; Constriction, Pathologic; Diethylcarbamazine; Guinea Pigs; Imidazoles; Male; Postmortem Changes; Pulmonary Circulation; SRS-A; Substance P; Thromboxane A2 | 1984 |
The effect of capsaicin on C-fiber reflex and heat evoked discharge in the acute spinal cat.
Topics: Afferent Pathways; Animals; Capsaicin; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Female; Male; Nerve Fibers; Nerve Fibers, Myelinated; Peroneal Nerve; Reflex; Spinal Nerve Roots; Substance P; Synaptic Transmission; Thermoreceptors | 1983 |
The role of substance P in the axon reflex in the rat.
Topics: Administration, Topical; Animals; Axons; Capillary Permeability; Capsaicin; Electric Stimulation; Infusions, Intra-Arterial; Microscopy, Electron; Muscles; Rats; Rats, Inbred Strains; Reflex; Substance P | 1984 |
Effects of cysteamine on pain behaviour and on somatostatin- and substance P-like immunoreactivity in the substantia gelatinosa of the rat.
Topics: Animals; Capsaicin; Cysteamine; Histocytochemistry; Hot Temperature; Male; Pain; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P; Substantia Gelatinosa | 1984 |
Biphasic time-course of capsaicin-induced substance P depletion: failure to correlate with thermal analgesia in the rat.
Topics: Animals; Capsaicin; Hot Temperature; Male; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Spinal Cord; Substance P | 1984 |
A mechanism for sympathectomy-induced bone resorption in the middle ear.
Topics: Animals; Animals, Newborn; Awards and Prizes; Bone and Bones; Bone Resorption; Calcium; Capsaicin; Cell Count; Culture Media; Ear, Middle; Gerbillinae; Hearing Disorders; Humans; In Vitro Techniques; Indomethacin; Mice; Nerve Growth Factors; Neuropeptides; Osteoclasts; Oxidopamine; Skull; Substance P; Sympathetic Nervous System | 1995 |
Modulation of acetylcholine, capsaicin and substance P effects by histamine H3 receptors in isolated perfused rabbit lungs.
Topics: Acetylcholine; Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Endothelium; Female; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Lung; Male; Nerve Fibers; Piperidines; Pulmonary Edema; Rabbits; Receptors, Histamine H3; Serotonin; Substance P; Thiourea | 1995 |
Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors.
Topics: Animals; Capsaicin; Cell Migration Inhibition; Interleukin-1; Male; Mice; Neutrophils; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P | 1993 |
Levodropropizine reduces capsaicin- and substance P-induced plasma extravasation in the rat trachea.
Topics: Animals; Antitussive Agents; Blood Pressure; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Heart Rate; In Vitro Techniques; Muscle Contraction; Peripheral Nervous System; Platelet Activating Factor; Propylene Glycols; Rats; Rats, Inbred F344; Substance P; Trachea; Urinary Bladder | 1993 |
[Sensory fibers sensitive to capsaicin can modulate secretion of the duodenal mucus. A morphometric study in rats].
Topics: Animals; Capsaicin; Duodenum; Intestinal Mucosa; Intestinal Secretions; Male; Neurons, Afferent; Pilocarpine; Rats; Rats, Wistar; Stimulation, Chemical; Substance P | 1993 |
Evidence that capsaicin hyperaemia of rat sciatic vasa nervorum is local, opiate-sensitive and involves mast cells.
Topics: Afferent Pathways; Amino Acid Sequence; Animals; Capsaicin; Male; Mast Cells; Molecular Sequence Data; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve; Substance P; Vasa Nervorum | 1993 |
Distribution and binding sites of substance P and calcitonin gene-related peptide and their capsaicin-sensitivity in the spinal cord of rats and chicken: a comparative study.
Topics: Animals; Autoradiography; Binding Sites; Calcitonin Gene-Related Peptide; Capsaicin; Chickens; Immunoenzyme Techniques; Iodine Radioisotopes; Rats; Spinal Cord; Substance P; Tissue Distribution | 1993 |
Evidence for substance P as an endogenous substance causing cough in guinea pigs.
Topics: Aerosols; Animals; Capsaicin; Cough; Dipeptides; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs; Indoles; Male; Neprilysin; Smoking; Substance P; Tachykinins | 1993 |
Neonatal capsaicin pretreatment suppresses intramedullary inflammation in adjuvant-induced spondylitis.
Topics: Animals; Animals, Newborn; Capsaicin; Male; Neurons, Afferent; Rats; Rats, Inbred Lew; Rats, Wistar; Spondylitis; Substance P | 1994 |
Substance P antagonist does not block the stimulation of rapidly adapting pulmonary stretch receptors by ammonia.
Topics: Administration, Inhalation; Ammonia; Animals; Capsaicin; Nerve Fibers; Nitroprusside; Pulmonary Stretch Receptors; Rabbits; Substance P | 1994 |
Depression of primary afferent-evoked responses by GR71251 in the isolated spinal cord of the neonatal rat.
Topics: Analgesics; Animals; Animals, Newborn; Capsaicin; Depression, Chemical; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Tachykinin; Reflex; Sensitivity and Specificity; Spinal Cord; Spinal Nerve Roots; Substance P; Synapses; Tachykinins | 1993 |
Substance P attenuates gastric mucosal hyperemia after stimulation of sensory neurons in the rat stomach.
Topics: Animals; Aprotinin; Blood Pressure; Capsaicin; Gastric Mucosa; Hyperemia; Male; Mast Cells; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Substance P; Vascular Resistance | 1994 |
Role of the NH2-terminus of substance P in the inhibition by capsaicin of behavioral sensitization to kainic acid-induced activity in the adult mouse.
Topics: Amides; Animals; Capsaicin; Drug Tolerance; Kainic Acid; Male; Mice; Motor Activity; Peptide Fragments; Substance P | 1994 |
Neonatal capsaicin treatment decreases airway and pulmonary tissue responsiveness to methacholine.
Topics: Aerosols; Animals; Animals, Newborn; Bronchi; Capsaicin; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Lung; Methacholine Chloride; Rats; Substance P | 1994 |
Pharmacological evidence that calcitonin gene-related peptide is implicated in cerebral autoregulation.
Topics: Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Capsaicin; Cerebrovascular Circulation; Cromakalim; Glyburide; Homeostasis; Neuropeptides; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide; Substance P; Vasodilator Agents | 1994 |
Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema.
Topics: Administration, Cutaneous; Animals; Arachidonic Acid; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cyproheptadine; Edema; Indomethacin; Male; Mice; Neuropeptides; Nifedipine; Substance P | 1993 |
Electrophysiological effects of tachykinins and capsaicin on guinea-pig bronchial parasympathetic ganglion neurones.
Topics: Animals; Bronchi; Capsaicin; Electrophysiology; Ganglia, Parasympathetic; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Tachykinins | 1993 |
Relative contribution of sympathetic and sensory nerves to thermal nociception and tissue trophism in rats.
Topics: Aging; Animals; Animals, Newborn; Capsaicin; Female; Hot Temperature; Male; Nervous System Physiological Phenomena; Nociceptors; Oxidopamine; Radioimmunoassay; Rats; Rats, Wistar; Sensation; Sensory Thresholds; Skin; Substance P; Sympathetic Nervous System | 1993 |
Sensory and sympathetic nerve sprouting in the rat cornea following neonatal administration of capsaicin.
Topics: Adrenergic Fibers; Age Factors; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cornea; Female; Ganglia, Sympathetic; Immunoenzyme Techniques; Keratitis; Male; Myelin Sheath; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Substance P; Thiolester Hydrolases; Trigeminal Ganglion; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase; Wound Healing | 1993 |
Role of substance P in rat carotid body responses to hypoxia and capsaicin.
Topics: Animals; Animals, Newborn; Blood Pressure; Capsaicin; Carotid Body; Dose-Response Relationship, Drug; Hypoxia; Neurokinin-1 Receptor Antagonists; Oxygen; Pressoreceptors; Rats; Rats, Sprague-Dawley; Reference Values; Substance P | 1993 |
Anti-edema action of formoterol in rat trachea does not depend on capsaicin-sensitive sensory nerves.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Afferent Pathways; Animals; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Endothelium, Vascular; Ethanolamines; Formoterol Fumarate; Injections, Intravenous; Male; Platelet Activating Factor; Premedication; Rats; Rats, Inbred F344; Substance P; Trachea; Tracheal Diseases | 1994 |
Capsaicin desensitization inhibits swallowing reflex in guinea pigs.
Topics: Acetylcholine; Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Deglutition; Dipeptides; Dose-Response Relationship, Drug; Electromyography; Guinea Pigs; Indoles; Lidocaine; Nerve Fibers; Premedication; Reflex; Substance P | 1994 |
An antinociceptive effect of capsaicin in the adult mouse mediated by the NH2-terminus of substance P.
Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Male; Mice; Neurotransmitter Agents; Peptide Fragments; Substance P | 1994 |
Protective role for neuropeptides in acute pulmonary response to acrolein in guinea pigs.
Topics: Acrolein; Animals; Bronchoalveolar Lavage Fluid; Capsaicin; Erythrocyte Count; Guinea Pigs; Leukocyte Count; Lung; Male; Nerve Fibers; Neuropeptides; Nodose Ganglion; Respiratory Mechanics; Substance P; Tachykinins; Thiorphan | 1993 |
Capsaicin pretreatment attenuates monocrotaline-induced ventilatory dysfunction and pulmonary hypertension.
Topics: Animals; Blood Pressure; Body Weight; Capsaicin; Cardiomegaly; Endopeptidases; Hypertension, Pulmonary; Monocrotaline; Nerve Fibers; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Respiratory Tract Diseases; Substance P | 1993 |
Budesonide inhibits plasma extravasation induced by capsaicin and by substance P in the rat nasal mucosa.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Budesonide; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Evans Blue; Glucocorticoids; Injections, Intravenous; Male; Nasal Mucosa; Pregnenediones; Rats; Rats, Inbred F344; Substance P | 1993 |
Subpopulations of neonatal rat sensory neurons express functional neurotransmitter receptors which elevate intracellular calcium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Bradykinin; Calcium; Capsaicin; Cell Size; Classification; Ganglia, Spinal; Intracellular Fluid; Neurons, Afferent; Rats; Receptors, Neurotransmitter; Substance P | 1994 |
Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs.
Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Perfusion; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Trachea | 1994 |
Protective function of extrinsic sensory neurons in acute rabbit experimental colitis.
Topics: Animals; Blotting, Northern; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Colon; Disease Models, Animal; Intestinal Mucosa; Male; Necrosis; Neurons, Afferent; Rabbits; Radioimmunoassay; Substance P; Time Factors | 1994 |
Endothelin-1 enhances capsaicin-induced peptide release and cGMP accumulation in cultures of rat sensory neurons.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic GMP; Endothelins; Ganglia, Spinal; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Substance P | 1994 |
Extrinsic denervation increases NADPH diaphorase staining in myenteric nerves of guinea pig ileum.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Guinea Pigs; Ileum; Male; Myenteric Plexus; NADPH Dehydrogenase; Neurons; Oxidopamine; Staining and Labeling; Substance P; Vasoactive Intestinal Peptide | 1994 |
Distinct populations of sensory neurons mediate the peristaltic reflex elicited by muscle stretch and mucosal stimulation.
Topics: Animals; Arginine; Atropine; Capsaicin; Colon; Electric Stimulation; In Vitro Techniques; Intestinal Mucosa; Male; Muscle Contraction; Muscle Denervation; Muscle Relaxation; Muscle, Smooth; Neurons, Afferent; Nitroarginine; Peristalsis; Rats; Rats, Sprague-Dawley; Substance P; Time Factors; Vasoactive Intestinal Peptide | 1994 |
"Capsaicin-sensitive" sensory neurons in cluster headache: pathophysiological aspects and therapeutic indication.
Topics: Administration, Intranasal; Animals; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Capsaicin; Cerebrovascular Circulation; Cluster Headache; Female; Humans; Male; Neurons, Afferent; Nose; Rats; Rats, Sprague-Dawley; Substance P | 1994 |
Involvement of substance P and excitatory amino acids in aversive behavior elicited by intrathecal capsaicin.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Avoidance Learning; Biphenyl Compounds; Capsaicin; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hypnotics and Sedatives; Injections, Spinal; Male; Nociceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Substance P; Synaptic Transmission | 1994 |
Effect of capsaicin on distribution of binding sites for tachykinins and calcitonin gene-related peptide in rat urinary bladder: a quantitative autoradiographic study.
Topics: Animals; Autoradiography; Calcitonin Gene-Related Peptide; Capsaicin; Male; Neurokinin A; Protein Binding; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Tachykinin; Substance P; Tissue Distribution; Urinary Bladder | 1994 |
Facilitatory effects of selective agonists for tachykinin receptors on cholinergic neurotransmission: evidence for species differences.
Topics: Adult; Amino Acid Sequence; Animals; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Parasympathetic Nervous System; Peptide Fragments; Rabbits; Receptors, Tachykinin; Substance P; Sulfones; Synaptic Transmission; Tachykinins | 1994 |
Effects of ageing on sensory nerve function in rat skin.
Topics: Afferent Pathways; Animals; Arginine; Blister; Capsaicin; Electric Stimulation; Female; Humans; Male; Neurons, Afferent; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve; Skin; Skin Aging; Substance P; Vasodilation | 1994 |
Capsaicin-induced bladder hyperactivity in normal conscious rats.
Topics: Administration, Intravesical; Animals; Benzamides; Capsaicin; Consciousness; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Indoles; Isoindoles; Morphine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Urinary Bladder | 1994 |
Capsaicin-sensitive stretch responses in ferret trachealis muscle.
Topics: Animals; Capsaicin; Female; Ferrets; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Stress, Mechanical; Substance P; Thiorphan; Trachea | 1994 |
Sodium nitroprusside evokes the release of immunoreactive calcitonin gene-related peptide and substance P from dorsal horn slices via nitric oxide-dependent and nitric oxide-independent mechanisms.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclic GMP; Ferricyanides; In Vitro Techniques; Male; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1994 |
Modulation of the acetylcholine- and substance P-induced pulmonary edema by calcitonin gene-related peptide in the rabbit.
Topics: Acetylcholine; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capillary Permeability; Capsaicin; Drug Interactions; Female; In Vitro Techniques; Lung; Male; Peptide Fragments; Pulmonary Circulation; Pulmonary Edema; Rabbits; Substance P | 1994 |
The effects of toluene diisocyanate and of capsaicin on human bronchial smooth muscle in vitro.
Topics: Acetylcholine; Aged; Bronchi; Capsaicin; Female; Humans; In Vitro Techniques; Isoproterenol; Isotonic Contraction; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Toluene 2,4-Diisocyanate | 1994 |
Neuropeptides in psoriasis: possible role of beta-endorphin in the pathomechanism of the disease.
Topics: beta-Endorphin; Capsaicin; Dermatitis, Atopic; Humans; Neuropeptides; Psoriasis; Scleroderma, Systemic; Skin; Substance P | 1994 |
Hair growth induction by substance P.
Topics: Animals; Capsaicin; Drug Implants; Hair; Injections, Subcutaneous; Mice; Mice, Inbred C57BL; Neprilysin; Osmolar Concentration; Skin; Substance P | 1994 |
Ventilatory responses to hypoxia in rats pretreated with nonpeptide NK1 receptor antagonist CP-96,345.
Topics: Animals; Animals, Newborn; Biphenyl Compounds; Capsaicin; Female; Hypnotics and Sedatives; Hypoxia; In Vitro Techniques; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Plethysmography; Rats; Rats, Inbred F344; Respiratory Function Tests; Respiratory Mechanics; Substance P; Tidal Volume | 1994 |
Nostril capsaicin application as a model of trigeminal primary sensory neuronal activation.
Topics: Administration, Intranasal; Adult; Calcitonin Gene-Related Peptide; Capsaicin; Cluster Headache; Female; Humans; Male; Neurons, Afferent; Radioimmunoassay; Saliva; Substance P; Trigeminal Nerve; Vasoactive Intestinal Peptide | 1994 |
Neonatal capsaicin treatment in rats results in scratching behavior with skin damage: potential model of non-painful dysesthesia.
Topics: Animals; Animals, Newborn; Behavior, Animal; Capsaicin; Disease Models, Animal; Injections, Spinal; Injections, Subcutaneous; Male; Morphine; Naloxone; Nerve Fibers; Rats; Rats, Sprague-Dawley; Self Mutilation; Skin; Substance P | 1994 |
Stimulation of gastric somatostatin mRNA abundance by substance P in capsaicin-treated rats.
Topics: Animals; Animals, Newborn; Blotting, Northern; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Mucosa; Rats; Rats, Wistar; RNA Probes; RNA, Messenger; Somatostatin; Stomach; Substance P | 1994 |
Modulation of carrageenan-induced hind paw edema by substance P.
Topics: Animals; Capsaicin; Carrageenan; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Foot; Organ Size; Rats; Rats, Sprague-Dawley; Substance P | 1994 |
Nonadrenergic noncholinergic nerves regulate basal coronary flow via release of capsaicin-sensitive neuropeptides in the rat heart.
Topics: Adenosine; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Circulation; Coronary Vessels; Dipeptides; Heart; Hemodynamics; Immunohistochemistry; In Vitro Techniques; Indoles; Male; Myocardium; Neuropeptides; Oxygen Consumption; Rats; Substance P; Ventricular Function, Left | 1994 |
Maturational changes in sympathetic and sensory innervation of the rat uterus: effects of neonatal capsaicin treatment.
Topics: Animals; Animals, Newborn; Blood Vessels; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Cervix Uteri; Female; Nerve Fibers; Neuronal Plasticity; Neurons, Afferent; Norepinephrine; Rats; Rats, Wistar; Sexual Maturation; Substance P; Sympathectomy, Chemical; Sympathetic Nervous System; Uterus | 1994 |
Corelease of neuropeptides from capsaicin-sensitive afferents dilates submucosal arterioles in guinea pig ileum.
Topics: Animals; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Capsaicin; Drug Interactions; Guinea Pigs; Ileum; Intestinal Mucosa; Neurons, Afferent; Neuropeptides; Peptide Fragments; Substance P; Synaptic Membranes; Vasodilation | 1994 |
Cutaneous vasodilatation induced by nitric oxide-evoked stimulation of afferent nerves in the rat.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Female; Indoles; Isoindoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Substance P; Vasodilation | 1994 |
Differential antinociceptive effects of sendide, a NK1-receptor antagonist, and morphine in the capsaicin test.
Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Neurokinin-1 Receptor Antagonists; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Substance P | 1994 |
Autonomic and sensory cardiovascular activities of nonivamide: intrathecal administration of clonidine.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Capsaicin; Cardiovascular System; Clonidine; Heart Rate; Infusions, Parenteral; Injections, Intra-Arterial; Injections, Intravenous; Male; Neurons, Afferent; Rats; Rats, Wistar; Spine; Substance P; Vanillic Acid | 1994 |
Tachykinin NK1 and NK2 receptors mediate atropine-resistant ileal circular muscle contractions evoked by capsaicin.
Topics: Amino Acid Sequence; Animals; Atropine; Capsaicin; Dipeptides; Drug Resistance; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Oligopeptides; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Ruthenium Red; Substance P; Tetrodotoxin | 1994 |
Substance P, calcitonin gene-related peptide, and capsaicin release serotonin from cerebrovascular mast cells.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Arteries; Dose-Response Relationship, Drug; Drug Synergism; Exocytosis; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Immunohistochemistry; In Vitro Techniques; Male; Mast Cells; Microscopy, Confocal; Microscopy, Electron; Nerve Endings; Rabbits; Reference Values; Serotonin; Substance P | 1994 |
Cationic protein-induced sensory nerve activation: role of substance P in airway hyperresponsiveness and plasma protein extravasation.
Topics: Animals; Blood Proteins; Bronchi; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Cations; Female; Glycopeptides; Male; Methacholine Chloride; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptides; Polylysine; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P | 1994 |
Substance P N-terminal metabolites and nitric oxide mediate capsaicin-induced antinociception in the adult mouse.
Topics: Analgesia; Animals; Arginine; Capsaicin; Dose-Response Relationship, Drug; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Substance P | 1994 |
Tachykinins and kinins in antigen-evoked plasma extravasation in guinea-pig nasal mucosa.
Topics: Animals; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Evans Blue; Glycopeptides; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Kinins; Male; Nasal Mucosa; Nerve Endings; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Ovalbumin; Protease Inhibitors; Substance P; Tachykinins | 1994 |
Involvement of enzymatic degradation in the inactivation of tachykinin neurotransmitters in neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Electrophysiology; Endopeptidases; In Vitro Techniques; Membranes; Motor Neurons; Naloxone; Neurokinin A; Protease Inhibitors; Rats; Rats, Wistar; Spinal Cord; Substance P; Synaptic Membranes | 1994 |
The phosphatase inhibitor, okadaic acid, increases peptide release from rat sensory neurons in culture.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Embryo, Mammalian; Ethers, Cyclic; Ganglia, Spinal; Neurons, Afferent; Okadaic Acid; Phosphoprotein Phosphatases; Potassium Chloride; Rats; Substance P | 1994 |
Effect of capsaicin on release of substance P-like immunoreactivity from vascularly perfused rat duodenum.
Topics: Animals; Capsaicin; Duodenum; Male; Rats; Rats, Wistar; Substance P | 1995 |
5-HT modulates noncholinergic contraction in guinea pig airways in vitro by prejunctional 5-HT1-like receptor.
Topics: Animals; Autonomic Nervous System; Capsaicin; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Norepinephrine; Receptors, Serotonin; Respiratory Physiological Phenomena; Respiratory System; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P | 1994 |
Sidestream cigarette smoke exposure and airway reactivity during early life.
Topics: Acetylcholine; Animals; Animals, Newborn; Body Weight; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Female; Guinea Pigs; Maximal Expiratory Flow-Volume Curves; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Respiration; Substance P; Tobacco Smoke Pollution | 1994 |
Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate.
Topics: Animals; Calcium; Capsaicin; Enzymes, Immobilized; Glutamate Dehydrogenase; Glutamic Acid; In Vitro Techniques; Male; Nerve Endings; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1994 |
Nitric oxide and cyclic guanosine 3',5'-monophosphate do not alter neuropeptide release from rat sensory neurons grown in culture.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic GMP; Molsidomine; Neurons, Afferent; Neuropeptides; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Substance P | 1994 |
Modulatory effect of neuropeptide Y on acetylcholine-induced oedema and vasoconstriction in isolated perfused lungs of rabbit.
Topics: Acetylcholine; Animals; Capsaicin; Female; Hemodynamics; Male; Neuropeptide Y; Perfusion; Permeability; Pulmonary Edema; Rabbits; Serotonin; Substance P; Vasoconstriction | 1994 |
The differential mechanisms of mild irritants on adaptive cytoprotection.
Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P | 1994 |
Intrathecal capsaicin enhances one-kidney renal wrap hypertension in the rat.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Desoxycorticosterone; Hypertension; Hypertension, Renovascular; Immunohistochemistry; Injections, Spinal; Male; Nerve Degeneration; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1994 |
Effect of substance P and capsaicin on urinary bladder of diabetic rats and the role of the epithelium.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Capsaicin; Diabetes Mellitus, Experimental; Epithelium; In Vitro Techniques; Male; Muscle, Smooth; Organ Size; Prostaglandins; Rats; Rats, Sprague-Dawley; Substance P; Time Factors; Urinary Bladder | 1994 |
The non-peptide neurokinin-1 antagonist, RPR 100893, decreases c-fos expression in trigeminal nucleus caudalis following noxious chemical meningeal stimulation.
Topics: Animals; Blood Proteins; Capsaicin; Guinea Pigs; Indoles; Isoindoles; Male; Meninges; Neurokinin-1 Receptor Antagonists; Pain; Proto-Oncogene Proteins c-fos; Substance P; Trigeminal Nuclei | 1995 |
Sidestream smoke effects on lung morphology and C-fibers in young guinea pigs.
Topics: Airway Obstruction; Animals; Atmosphere Exposure Chambers; Capsaicin; Guinea Pigs; In Vitro Techniques; Lung; Male; Nerve Fibers; Pulmonary Alveoli; Substance P; Tobacco Smoke Pollution | 1995 |
[Experimental study on blocking agent of substance P nerves in the treatment of allergic rhinitis].
Topics: Animals; Capsaicin; Guinea Pigs; Male; Nasal Mucosa; Rhinitis, Allergic, Perennial; Substance P | 1994 |
Capsaicin effects on substance P and CGRP in rat adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Female; Ganglia, Spinal; Immunohistochemistry; Organ Size; Rats; Rats, Inbred Lew; Substance P; Synovial Membrane; Tarsus, Animal; Up-Regulation | 1995 |
An investigation into the mechanism of capsaicin-induced oedema in rabbit skin.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Catalase; Dexamethasone; Drug Interactions; Edema; Histamine; Indoles; Indomethacin; Injections, Intradermal; Injections, Intravenous; Isoindoles; Male; Piperidines; Rabbits; Regional Blood Flow; Ruthenium Red; Skin; Substance P; Vasodilator Agents | 1995 |
Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Indoles; Indomethacin; Injections, Spinal; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Quinuclidines; Rats; Rats, Wistar; Reflex; Substance P; Urinary Bladder | 1995 |
Hypertonicity, but not hypothermia, elicits substance P release from rat C-fiber neurons in primary culture.
Topics: Animals; Animals, Newborn; Calcium; Capsaicin; Cells, Cultured; Cold Temperature; Ganglia, Spinal; Glycerol; Hypertonic Solutions; Kinetics; Mannitol; Neurons; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Substance P; Sucrose; Time Factors | 1995 |
Tachykinin NK1 and NK2 receptors mediate the non-cholinergic bronchospastic response to capsaicin and vagal stimulation in guinea-pigs.
Topics: Animals; Biphenyl Compounds; Bronchial Spasm; Capsaicin; Electric Stimulation; Guinea Pigs; Insufflation; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Vagus Nerve | 1995 |
Modulation of sympathetic vasoconstriction by sensory nerves and nitric oxide in rat irideal arterioles.
Topics: Animals; Arterioles; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Immunohistochemistry; In Vitro Techniques; Iris; Neurons, Afferent; Nitric Oxide; Rats; Receptors, Neuropeptide; Substance P; Vasoconstriction | 1995 |
Inhibition of neutral endopeptidase increases airway responsiveness to ACh in nonsensitized normal rats.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bronchial Hyperreactivity; Capillary Permeability; Capsaicin; Carbachol; Glycopeptides; In Vitro Techniques; Male; Muscle, Smooth; Neprilysin; Neurokinin A; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Respiratory System; Substance P; Vagotomy | 1995 |
Neutral endopeptidase modulates substance P-induced vasodilation in vivo.
Topics: Animals; Arterioles; Blood Pressure; Capsaicin; Cricetinae; Glycopeptides; Male; Mesocricetus; Mouth Mucosa; Neprilysin; Nitroglycerin; Protease Inhibitors; Regional Blood Flow; Substance P; Vasodilation | 1995 |
Neurokinin depletion attenuates pulmonary changes induced by antigen challenge in sensitized guinea pigs.
Topics: Animals; Antigens; Capsaicin; Guinea Pigs; Immunization; Immunoglobulin E; Immunoglobulin G; Lung; Male; Neurokinin A; Ovalbumin; Substance P | 1995 |
Scratching behavior induced by pruritogenic but not algesiogenic agents in mice.
Topics: Animals; Behavior, Animal; Capsaicin; Formaldehyde; Histamine; Male; Mice; p-Methoxy-N-methylphenethylamine; Pain; Pruritus; Substance P | 1995 |
Noxious peripheral stimulation produces antinociception mediated via substance P and opioid mechanisms in the rat tail-flick test.
Topics: Animals; Capsaicin; Endorphins; Hindlimb; Hot Temperature; Immersion; Male; Naloxone; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Substance P | 1995 |
Capsaicin pretreatment attenuates chronic hypoxic pulmonary hypertension.
Topics: Animals; Blood Pressure; Capsaicin; Chronic Disease; Female; Hypertension, Pulmonary; Hypoxia; Neprilysin; Pulmonary Circulation; Random Allocation; Rats; Rats, Wistar; Substance P; Tachykinins | 1995 |
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation.
Topics: Animals; Capsaicin; Dendrites; Endocytosis; GTP-Binding Proteins; Male; Neuronal Plasticity; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1995 |
Effect of substance P and capsaicin on stomach fundus and ileum of streptozotocin-diabetic rats.
Topics: Acetylcholine; Age Factors; Animals; Capsaicin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gastric Fundus; Ileum; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Sprague-Dawley; Streptozocin; Substance P | 1995 |
Substance P-induced histamine release in tracheally perfused guinea pig lungs.
Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Mast Cells; Perfusion; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1995 |
Autonomic regulation of tissue resistance in the guinea pig lung.
Topics: Airway Resistance; Animals; Atropine; Autonomic Nervous System; Capsaicin; Guinea Pigs; Lung; Phentolamine; Propranolol; Respiration, Artificial; Substance P; Tachykinins; Vagotomy; Vasoactive Intestinal Peptide | 1995 |
C-fiber-evoked autonomic cardiovascular effects after injection of Piper betle inflorescence extracts.
Topics: Animals; Areca; Atropine; Blood Pressure; Capsaicin; Chromatography, High Pressure Liquid; Clonidine; Eugenol; Heart Rate; Injections, Intra-Arterial; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Male; Plant Extracts; Plants, Medicinal; Propranolol; Rats; Rats, Wistar; Safrole; Substance P; Vagotomy | 1995 |
Neuropeptidergic and autonomic control of the vasculature of the rat knee joint revealed by laser Doppler perfusion imaging.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Capsaicin; Electric Stimulation; Epinephrine; Knee Joint; Laser-Doppler Flowmetry; Male; Perfusion; Rats; Rats, Wistar; Substance P; Sympathetic Nervous System; Vasodilation | 1995 |
Involvement of tachykinins in plasma extravasation induced by bradykinin and low pH medium in the guinea-pig conjunctiva.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Conjunctiva; Guinea Pigs; Hydrogen-Ion Concentration; Male; Neuritis; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Bradykinin; Substance P; Tachykinins | 1995 |
Sensory nerve- and neuropeptide-mediated relaxation responses in airways of Sprague-Dawley rats.
Topics: Animals; Bethanechol; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Neuropeptides; Rats; Rats, Sprague-Dawley; Substance P; Tetrodotoxin; Trachea | 1995 |
Role of C fibers in physiological responses to ozone in rats.
Topics: Aerosols; Animals; Animals, Newborn; Body Temperature; Capsaicin; Female; Heart Rate; Lung Compliance; Male; Methacholine Chloride; Nerve Fibers; Neurokinin A; Ozone; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Substance P | 1995 |
Calcitonin gene-related peptide mediated neurogenic vasorelaxation in the isolated canine lingual artery.
Topics: Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Capsaicin; Cromakalim; Dogs; Electric Stimulation; Female; Glyburide; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Peptide Fragments; Potassium Channel Blockers; Potassium Channels; Propranolol; Pyrroles; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vasoconstriction; Vasodilator Agents | 1995 |
Neurogenic inflammation in human airways: is it important?
Topics: Administration, Topical; Airway Resistance; Animals; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Humans; Nasal Mucosa; Neprilysin; Neurokinin A; Rhinitis, Allergic, Seasonal; Substance P | 1995 |
Activity of SR 142801 at peripheral tachykinin receptors.
Topics: Analysis of Variance; Animals; Binding, Competitive; Capsaicin; Cricetinae; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Portal Vein; Pulmonary Artery; Rabbits; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Trachea | 1995 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1995 |
Neuropeptide depletion impairs postischemic recovery of the isolated rat heart: role of substance P.
Topics: Animals; Capsaicin; In Vitro Techniques; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Neuropeptides; Rats; Rats, Sprague-Dawley; Substance P | 1995 |
Evidence for afferent fiber innervation of parasympathetic neurons of the guinea-pig cardiac ganglion.
Topics: Animals; Biotin; Capsaicin; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Ganglia, Parasympathetic; Guinea Pigs; Heart; Immunohistochemistry; Male; Neurons, Afferent; Parasympathetic Fibers, Postganglionic; Receptors, Tachykinin; Substance P; Synapses; Tachykinins | 1995 |
Vagal nerve stimulation of the guinea-pig oesophagus.
Topics: Animals; Atropine; Calcium Channel Blockers; Capsaicin; Electric Stimulation; Esophagus; Ganglionic Blockers; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; omega-Conotoxin GVIA; Peptides; Physostigmine; Substance P; Thiorphan; Tubocurarine; Vagus Nerve | 1995 |
Central versus peripheral site of action of the tachykinin NK1-antagonist RP 67580 in inhibiting chemonociception.
Topics: Analgesics; Animals; Blood Pressure; Blood-Brain Barrier; Capsaicin; Female; Hydrochloric Acid; Indoles; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Stereoisomerism; Substance P | 1995 |
Potentiation by viral respiratory infection of ovalbumin-induced guinea-pig tracheal hyperresponsiveness: role for tachykinins.
Topics: Animals; Arecoline; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hypersensitivity; Male; Ovalbumin; Respiratory Tract Infections; Substance P; Tachykinins; Trachea; Virus Cultivation | 1995 |
Dexamethasone reduces tachykinin but not ACh airway hyperreactivity after O3.
Topics: Acetylcholine; Airway Resistance; Animals; Anti-Bacterial Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Guinea Pigs; Male; Neprilysin; Oligopeptides; Ozone; Peptides; Substance P; Tachykinins | 1993 |
Lack of effect of sumatriptan and UK-14,304 on capsaicin-induced relaxation of guinea-pig isolated basilar artery.
Topics: Animals; Basilar Artery; Brimonidine Tartrate; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indoles; Male; Quinoxalines; Ruthenium Red; Substance P; Sulfonamides; Sumatriptan; Vasoconstrictor Agents; Vasodilation | 1993 |
Inhibition of neutral endopeptidase augments anaphylactic constriction of guinea pig tracheal smooth muscle.
Topics: Anaphylaxis; Animals; Capsaicin; Female; Glycopeptides; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Neprilysin; Substance P; Tachykinins; Trachea | 1993 |
Neurogenic inflammation in nasal allergy: histochemical and pharmacological studies in guinea pigs. A review.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Desensitization, Immunologic; Fluorescent Antibody Technique; Guinea Pigs; Male; Nerve Endings; Nerve Fibers; Neural Pathways; Neurons, Afferent; Nose Diseases; Nucleic Acid Hybridization; Respiratory Hypersensitivity; Substance P; Toluene 2,4-Diisocyanate; Trigeminal Ganglion | 1993 |
Effect of neonatal capsaicin treatment on neurogenic pulmonary edema from fluid-percussion brain injury in the adult rat.
Topics: Animals; Animals, Newborn; Brain Injuries; Capsaicin; Hemorrhage; Histamine Antagonists; Neurons, Afferent; Percussion; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Substance P; Surface Tension | 1993 |
The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biphenyl Compounds; Capsaicin; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurokinin A; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Spinal Cord; Substance P; Synapses; Synaptic Transmission | 1993 |
Effects of topical capsaicin on autonomic nerves in experimentally-induced nasal hypersensitivity. An immunocytochemical study.
Topics: Administration, Intranasal; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Female; Guinea Pigs; Nasal Mucosa; Olfactory Bulb; Rhinitis, Allergic, Perennial; Substance P; Toluene 2,4-Diisocyanate; Tyrosine 3-Monooxygenase | 1993 |
Cardiovascular interactions of nonivamide, glyceryl nonivamide, capsaicin analogues, and substance P antagonist in rats.
Topics: Animals; Blood Pressure; Capsaicin; Drug Interactions; Glycerol; Heart Rate; Hemodynamics; Indicators and Reagents; Injections, Intraperitoneal; Injections, Spinal; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Wistar; Substance P; Vagotomy; Vanillic Acid; Vasodilation | 1993 |
Tachykinin control of ferret airways: mucus secretion, bronchoconstriction and receptor mapping.
Topics: Animals; Bronchoconstriction; Capsaicin; Ferrets; Male; Methacholine Chloride; Mucus; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Reproducibility of Results; Stimulation, Chemical; Substance P; Tachykinins; Trachea | 1993 |
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo.
Topics: Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Dipeptides; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Hypotension; Indoles; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Smoking; Substance P; Vagus Nerve | 1993 |
Capsaicin inhibits whereas rhizotomy potentiates substance P-induced release of excitatory amino acids in the rat spinal cord in vivo.
Topics: Animals; Aspartic Acid; Capsaicin; Glutamates; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley; Reference Values; Spinal Cord; Spinal Nerves; Substance P | 1993 |
Effect of frusemide on bradykinin- and capsaicin-induced contraction of the guinea-pig trachea.
Topics: Animals; Bradykinin; Bronchoconstriction; Capsaicin; Furosemide; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Substance P; Trachea | 1993 |
Neurogenic vasodilation in the rat nasal mucosa involves neurokinin1 tachykinin receptors.
Topics: Animals; Capsaicin; Male; Neurons, Afferent; Olfactory Mucosa; Piperidines; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Vasodilation | 1993 |
Effects of capsaicin, (+/-)-CP-96,345 and SR 48968 on the bradykinin-induced airways microvascular leakage in guinea-pigs.
Topics: Animals; Autonomic Nervous System; Benzamides; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Evans Blue; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Nerve Endings; Neurokinin A; Piperidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Effectiveness of levodropropizine against cigarette smoke-induced airway hyperreactivity: possible mechanism.
Topics: Airway Resistance; Animals; Antitussive Agents; Bronchoconstriction; Capsaicin; Codeine; Guinea Pigs; Male; Propylene Glycols; Substance P; Tobacco Smoke Pollution | 1993 |
Neonatal capsaicin exposure affects isolation-induced aggressive behavior and hypothalamic substance P levels of adult male mice (Mus musculus).
Topics: Aggression; Agonistic Behavior; Animals; Animals, Newborn; Capsaicin; Hypothalamus; Injections, Subcutaneous; Male; Mice; Nociceptors; Pain Threshold; Social Isolation; Substance P; Thermosensing | 1993 |
A non-peptide NK1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Capsaicin; Electric Stimulation; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Morphine; Mucus; Nasal Mucosa; Pyrroles; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synapses; Thiophenes; Xylenes | 1993 |
Role of substance P (SP) in development of symptoms of neurogenic inflammation in the oral mucosa of the rat.
Topics: Analysis of Variance; Animals; Capillary Permeability; Capsaicin; Connective Tissue; Gingivitis; Immunohistochemistry; Male; Mouth Mucosa; Rats; Rats, Wistar; Substance P | 1993 |
Antinociception induced by CP 96,345, a non-peptide NK-1 receptor antagonist, in the mouse formalin and capsaicin tests.
Topics: Analgesics; Animals; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Formaldehyde; Hypnotics and Sedatives; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Naloxone; Pain; Pain Measurement; Postural Balance; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Involvement of capsaicin-sensitive afferent nerves in the intestinal motor alterations induced by intestinal anaphylaxis in rats.
Topics: Afferent Pathways; Anaphylaxis; Animals; Atropine; Biphenyl Compounds; Capsaicin; Electromyography; Female; Gastrointestinal Motility; Intestine, Small; Muscle, Smooth; Ovalbumin; Rats; Substance P | 1993 |
Effects of an NK1 receptor antagonist, FK888, on constriction and plasma extravasation induced in guinea pig airway by neurokinins and capsaicin.
Topics: Animals; Capillary Permeability; Capsaicin; Dipeptides; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Trachea | 1993 |
Sensory neuropeptides and hypoxic pulmonary vasoconstriction in the rat.
Topics: Angiotensin II; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Hypoxia; Lung; Male; Neuropeptides; Organ Culture Techniques; Rats; Rats, Wistar; Sciatic Nerve; Substance P; Vasoconstriction | 1993 |
A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline.
Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hypertonic Solutions; Neurokinin A; Neurons, Afferent; Piperidines; Platelet Activating Factor; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Tachykinin; Sodium Chloride; Stimulation, Chemical; Substance P; Trachea; Tracheal Diseases | 1993 |
NK1 receptors mediate neurogenic inflammatory increase in blood flow in rat airways.
Topics: Animals; Capsaicin; Inflammation; Male; Microspheres; Neurons, Afferent; Peptidyl-Dipeptidase A; Piperidines; Rats; Rats, Inbred F344; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Regional Blood Flow; Respiratory System; Respiratory Tract Diseases; Substance P; Tachykinins; Vasodilation | 1993 |
Impaired sensorineural function after allergen-induced mediator release.
Topics: Acetylcholine; Airway Resistance; Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Carbon Dioxide; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Male; Neurokinin A; Neurotransmitter Agents; Ovalbumin; Respiration Disorders; Substance P; Tidal Volume | 1993 |
Role of neuropeptides in acetylcholine-induced edema in isolated and perfused rabbit lungs.
Topics: Acetylcholine; Animals; Arachidonic Acid; Capillary Permeability; Capsaicin; Female; Male; Neuropeptides; Papaverine; Perfusion; Pulmonary Edema; Rabbits; Receptors, Serotonin; Serotonin; Substance P | 1993 |
Endogenous tachykinins facilitate transmission through parasympathetic ganglia in guinea-pig trachea.
Topics: Acetylcholine; Animals; Capsaicin; Electric Stimulation; Ganglia, Parasympathetic; Glycopeptides; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neuropeptides; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Synaptic Transmission; Tachykinins; Trachea; Vagus Nerve | 1993 |
Adenosine inhibits efferent function of extrinsic capsaicin-sensitive sensory nerves in the enteric nervous system.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Capsaicin; Electric Stimulation; Electrophysiology; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mesentery; Muscle Contraction; Myenteric Plexus; Nerve Fibers; Neurons, Afferent; Neurons, Efferent; Substance P; Theophylline | 1993 |
Vanilloid receptors in the urinary bladder: regional distribution, localization on sensory nerves, and species-related differences.
Topics: Animals; Animals, Newborn; Capsaicin; Cricetinae; Denervation; Diterpenes; Guinea Pigs; In Vitro Techniques; Mesocricetus; Mice; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Drug; Species Specificity; Substance P; Urinary Bladder | 1993 |
Changes in contractile responses of the urinary bladder to substance P in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Capsaicin; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Organ Size; Prostaglandins; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Urinary Bladder | 1993 |
NK1 receptors mediate tachykinin-induced increase in microvascular clearance in hamster cheek pouch.
Topics: Animals; Biphenyl Compounds; Capsaicin; Cheek; Cricetinae; Macromolecular Substances; Male; Mesocricetus; Microcirculation; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tachykinins | 1993 |
Involvement of CGRP, substance P and blood circulation in aggravating mechanism of absolute ethanol-induced antral lesions by capsaicin treatment in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Ethanol; Gastric Mucosa; Male; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach; Substance P | 1993 |
Inhibition of neurogenic inflammation in the meninges by a non-peptide NK1 receptor antagonist, RP 67580.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Dura Mater; Guinea Pigs; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Meninges; Migraine Disorders; Rats; Rats, Wistar; Stereoisomerism; Substance P | 1993 |
Neuroregulation of a chemosensitive afferent system in the canine distal esophagus.
Topics: Afferent Pathways; Animals; Atropine; Blood Pressure; Capsaicin; Chemoreceptor Cells; Dogs; Esophagus; Hexamethonium; Hexamethonium Compounds; Mucous Membrane; Nociceptors; Piperidines; Pressure; Pulse; Respiration; Substance P; Tetrodotoxin; Vagotomy | 1993 |
Functional and morphological characteristics of neuronal substance P in the canine gastroesophageal junction.
Topics: Animals; Blood Pressure; Capsaicin; Chromatography, High Pressure Liquid; Dogs; Esophagus; Immunohistochemistry; Mucous Membrane; Neurons; Pressure; Pulse; Radioimmunoassay; Respiration; Stomach; Substance P | 1993 |
Relations of contractile hyperreactivity to tachykinins in rabbit trachea.
Topics: Acetylcholine; Alternaria; Analgesics; Animals; Antigens, Fungal; Atropine; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Hypersensitivity; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Rabbits; Reference Values; Serotonin; Substance P; Tetrodotoxin; Trachea | 1993 |
Neurokinin A, but not neurokinin B and substance P, induces codeine-resistant coughs in awake guinea-pigs.
Topics: Animals; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Drug Resistance; Guinea Pigs; Male; Neurokinin A; Neurokinin B; Substance P | 1993 |
Interaction of substance P and leukotriene C4 in ethanol-induced mucosal injury of rat stomach.
Topics: Analgesics; Animals; Arterioles; Capsaicin; Ethanol; Gastric Juice; Intestinal Mucosa; Leukotriene C4; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Substance P; Venules | 1993 |
The role of substance P in the pathogenesis of experimental allergic neuritis.
Topics: Animals; Capsaicin; Cattle; Concanavalin A; Freund's Adjuvant; Ganglia, Spinal; Guinea Pigs; Lymphocyte Activation; Myelin Basic Protein; Neuritis, Autoimmune, Experimental; Spinal Cord; Spleen; Substance P | 1993 |
Does substance P release mediate NANC nerve-mediated responses to field stimulation and ligands, in the rabbit isolated sphincter pupillae?
Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; Isometric Contraction; Male; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Physalaemin; Pupil; Rabbits; Receptors, Tachykinin; Structure-Activity Relationship; Substance P; Tachykinins | 1993 |
Differences in the potency of CP-96345 and RP-67580, two new non-peptide antagonists selective for NK1 receptors, in inhibiting responses evoked by stimulation of sensory nerves.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Bronchi; Capsaicin; Electric Stimulation; Guanethidine; Guinea Pigs; Indoles; Isoindoles; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Regional Blood Flow; Skin; Substance P; Ureter | 1993 |
The pharmacological properties of FK888, a novel dipeptide NK1 antagonist.
Topics: Animals; Bronchoconstriction; Capsaicin; Cell Membrane; Dipeptides; Edema; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Indoles; Kinetics; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-1; Substance P | 1993 |
Spinal effects of selective NK-1 and NK-2 receptor antagonists on bladder motility in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Afferent Pathways; Animals; Capsaicin; Indoles; Isoindoles; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Reflex; Spinal Cord; Substance P; Urinary Bladder; Urination | 1993 |
The effects of NK-1 and NK-2 receptor antagonists on the capsaicin evoked synaptic response in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biphenyl Compounds; Capsaicin; In Vitro Techniques; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Spinal Cord; Substance P; Synapses | 1993 |
Desensitizing mechanism of capsaicin and nonanoyl vanillylamide on the vascular nociceptive response in the guinea pig.
Topics: Acetylcholine; Animals; Bradykinin; Capsaicin; Ganglia, Spinal; Guinea Pigs; Injections, Intra-Arterial; Injections, Spinal; Injections, Subcutaneous; Male; Pain; Spinal Cord; Substance P; Vanillic Acid; Vocalization, Animal | 1993 |
The amino-terminus of substance P mimics and MK-801 attenuates the effects of capsaicin on nociception and kainic acid-induced behavior in the mouse.
Topics: Analysis of Variance; Animals; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; Pain; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Substance P | 1993 |
Effect of CP-96,345 a non-peptide substance P antagonist, capsaicin, resiniferatoxin and ruthenium red on nociception.
Topics: Action Potentials; Analgesics; Animals; Biphenyl Compounds; Capsaicin; Diterpenes; Hot Temperature; Injections, Spinal; Pain; Peripheral Nerves; Rats; Ruthenium Red; Spinal Cord; Spinal Nerve Roots; Stereoisomerism; Substance P | 1993 |
Substance P in the guinea-pig hearing organ.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cochlea; Epithelium; Guinea Pigs; Nerve Fibers; Substance P | 1993 |
Role of prostaglandins in renal sensory receptor activation by substance P and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Dose-Response Relationship, Drug; Indomethacin; Kidney; Male; Nervous System; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Substance P | 1993 |
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors.
Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1993 |
MK-801 inhibits the effects of capsaicin in the adult mouse by an action involving phencyclidine (PCP) sites not linked to NMDA activity.
Topics: Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Injections, Spinal; Kainic Acid; Male; Mice; Pain Measurement; Pain Threshold; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Substance P | 1993 |
Pulmonary mechanical responses to intravenously administered capsaicin in guinea-pigs: effect of peptidase inhibitors.
Topics: Airway Resistance; Animals; Bronchoconstriction; Capsaicin; Guinea Pigs; Injections, Intravenous; Lung; Male; Protease Inhibitors; Respiration; Respiratory Mechanics; Substance P | 1993 |
Muscarinic excitatory and inhibitory mechanisms involved in afferent fibre-evoked depolarization of motoneurones in the neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Arecoline; Capsaicin; Edrophonium; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Motor Neurons; Muscarinic Antagonists; Neurons, Afferent; Nociceptors; Oxotremorine; Parasympathomimetics; Physical Stimulation; Rats; Rats, Wistar; Receptors, Muscarinic; Reflex, Monosynaptic; Skin Physiological Phenomena; Spinal Cord; Substance P | 1993 |
Tachykinin-mediated respiratory effects in conscious guinea pigs: modulation by NK1 and NK2 receptor antagonists.
Topics: Aerosols; Animals; Biphenyl Compounds; Capsaicin; Cell Membrane; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuropeptides; Receptors, Neurokinin-2; Respiration; Substance P; Tachykinins | 1993 |
Antinociceptive effects in the formalin and capsaicin tests after intrathecal administration of substance P analogues in mice.
Topics: Analgesics; Animals; Capsaicin; Drug Interactions; Formaldehyde; Injections, Spinal; Male; Mice; Naloxone; Pain; Substance P | 1993 |
Spinal adenosine modulates capsaicin-induced depressor reflex: involvement of adenosine A2 receptor.
Topics: Adenosine; Animals; Blood Pressure; Capsaicin; Hemodynamics; Injections, Spinal; Male; Nerve Fibers; Neurons, Afferent; Peptide Fragments; Rats; Rats, Wistar; Receptors, Purinergic P1; Reflex; Spinal Cord; Substance P; Theophylline | 1993 |
Pharmacology of CP-99,994; a nonpeptide antagonist of the tachykinin neurokinin-1 receptor.
Topics: Animals; Binding, Competitive; Calcium Channels; Capillary Permeability; Capsaicin; Cells, Cultured; Cricetinae; Guinea Pigs; Humans; In Vitro Techniques; Locus Coeruleus; Male; Motor Activity; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Species Specificity; Substance P | 1993 |
The analgesia induced by intrathecal injection of ruthenium red.
Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain; Pain Measurement; Ruthenium Red; Substance P | 1993 |
Effects of adenosine A2 receptor agonists on the excitation of capsaicin-sensitive afferent sensory nerves in airway tissues.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Bronchi; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neurons, Afferent; Nicotiana; Phenethylamines; Plants, Toxic; Rats; Rats, Wistar; Receptors, Purinergic P1; Smoke; Substance P; Trachea | 1993 |
Characterization of neurogenic inflammation in the airways of two highly inbred rat strains.
Topics: Animals; Benzamides; Blood Pressure; Bronchi; Capillary Permeability; Capsaicin; Cimetidine; Coloring Agents; Dose-Response Relationship, Drug; Evans Blue; Histamine Antagonists; Indoles; Inflammation; Isoindoles; Methysergide; Neurokinin-1 Receptor Antagonists; Piperidines; Pyrilamine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Neurokinin-1; Serotonin; Serotonin Antagonists; Substance P; Trachea | 1995 |
Abnormal intraepithelial airway nerves in persistent unexplained cough?
Topics: Adult; Aged; Bronchi; Bronchoscopy; Calcitonin Gene-Related Peptide; Capsaicin; Cough; Epithelium; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Tissue Proteins; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase | 1995 |
Cholecystokinin-octapeptide (CCK-OP) and substance P (SP) influence immune response to cholera toxin in live animals.
Topics: Administration, Oral; Animals; Bacterial Outer Membrane Proteins; Capsaicin; Cholera Toxin; Cholera Vaccines; Immunization, Secondary; Mice; Mice, Inbred C57BL; Sincalide; Substance P | 1995 |
An immunohistochemical and monastral blue-vascular labelling study on the involvement of capsaicin-sensitive sensory innervation of the junctional epithelium in neurogenic plasma extravasation in the rat gingiva.
Topics: Animals; Calcitonin Gene-Related Peptide; Capillaries; Capillary Permeability; Capsaicin; Coloring Agents; Epithelial Attachment; Gingiva; Gingivitis; Hyperplasia; Immunohistochemistry; Indoles; Male; Neovascularization, Pathologic; Neurons, Afferent; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Substance P; Venules | 1995 |
Horseradish peroxidase permeability across rat nasal mucosa in selective stimulation of substance P innervation with capsaicin.
Topics: Alkaloids; Animals; Capsaicin; Cytoplasm; Epithelial Cells; Epithelium; Horseradish Peroxidase; Immunoenzyme Techniques; Male; Microscopy, Electron; Nasal Mucosa; Radioimmunoassay; Rats; Substance P; Tight Junctions | 1995 |
Modification of vasoconstrictor responses in cerebral blood vessels by lesioning of the trigeminal nerve: possible involvement of CGRP.
Topics: Animals; Brain; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Cerebral Arteries; Cerebral Veins; In Vitro Techniques; Substance P; Trigeminal Nerve; Vasoconstriction; Vasodilation; Vasomotor System | 1995 |
The involvement of calcitonin gene-related peptide (CGRP) and substance P in feline pial artery diameter responses evoked by capsaicin.
Topics: Anesthetics; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Cerebral Arteries; Female; Injections, Intravenous; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Substance P; Trigeminal Nerve; Vasomotor System | 1995 |
Neurogenic influences on contralateral responses during experimental rat monoarthritis.
Topics: Analysis of Variance; Animals; Arthritis; Arthropathy, Neurogenic; Capsaicin; Cell Count; Ganglia, Spinal; Male; Microspheres; Rats; Rats, Wistar; Substance P; Vasomotor System | 1995 |
Neuropeptide modulation of chemically induced skin irritation.
Topics: Administration, Cutaneous; Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Relationship, Drug; Ear, External; Female; Irritants; Mice; Mice, Inbred BALB C; Neurokinin A; Neuropeptides; Piperidines; Skin; Substance P; Synaptic Transmission | 1995 |
Angiotensin-converting enzyme inhibitor and danazol increase sensitivity of cough reflex in female guinea pigs.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Capsaicin; Cilazapril; Citrates; Citric Acid; Cough; Cyclic AMP; Danazol; Dipeptides; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Guinea Pigs; Indoles; Procaterol; Reflex; Sex Factors; Substance P; Trachea | 1996 |
Peripheral GABAA receptor-mediated effects of sodium valproate on dural plasma protein extravasation to substance P and trigeminal stimulation.
Topics: Animals; Baclofen; Blood Pressure; Capillary Permeability; Capsaicin; Dura Mater; Electric Stimulation; Extravasation of Diagnostic and Therapeutic Materials; GABA Agents; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Heart Rate; Iodine Radioisotopes; Male; Muscimol; Neuritis; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Serum Albumin, Bovine; Substance P; Trigeminal Ganglion; Valproic Acid | 1995 |
Stable VIP analogue Ro-24-9981 potentiates substance P-induced plasma exudation in hamster cheek pouch.
Topics: Animals; Arginine; Calcimycin; Capsaicin; Cheek; Cricetinae; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethacin; Ionophores; Male; Microcirculation; Mouth Mucosa; NG-Nitroarginine Methyl Ester; Peptides, Cyclic; Plasma; Substance P; Vasoactive Intestinal Peptide | 1995 |
[Clinical observation and therapeutic mechanism of blocking agent of substance P nerves in the treatment of perennial allergic rhinitis].
Topics: Administration, Intranasal; Adolescent; Adult; Capsaicin; Female; Humans; Male; Nasal Mucosa; Neurotransmitter Uptake Inhibitors; Radioimmunoassay; Rhinitis, Allergic, Perennial; Substance P | 1995 |
Antitussive and antibronchoconstriction actions of fenspiride in guinea-pigs.
Topics: Acetates; Acetic Acid; Aerosols; Airway Resistance; Animals; Antitussive Agents; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neurokinin A; Spiro Compounds; Substance P | 1995 |
Genetic control of indirect airway responsiveness in the rat.
Topics: Adenosine; Animals; Atropine; Blood Proteins; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Capillary Permeability; Capsaicin; Male; Methysergide; Nedocromil; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Respiratory Function Tests; Serotonin; Serotonin Antagonists; Specific Pathogen-Free Organisms; Substance P; Tachykinins | 1995 |
RP67580, a neurokinin1 receptor antagonist, decreased restraint stress-induced defecation in rat.
Topics: Analgesics; Animals; Benzamides; Capsaicin; Defecation; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Restraint, Physical; Stereoisomerism; Stress, Psychological; Substance P | 1995 |
Involvement of substance P as a mediator in capsaicin-induced mouse ear oedema.
Topics: Animals; Capillary Permeability; Capsaicin; Ear Diseases; Edema; Male; Mice; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tachyphylaxis | 1995 |
Capsaicin-induced release of substance P increases cochlear blood flow in the guinea pig.
Topics: Animals; Blood Flow Velocity; Capsaicin; Cochlea; Female; Guinea Pigs; Homeostasis; Male; Neurons, Afferent; Substance P | 1995 |
Effects of streptozotocin-induced diabetes and insulin treatment on substance P of the rat arterial wall.
Topics: Animals; Aorta, Thoracic; Arteries; Blood Glucose; Body Weight; Capsaicin; Diabetes Mellitus, Experimental; Insulin; Male; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Sensory denervation by neonatal capsaicin treatment exacerbates Mycoplasma pulmonis infection in rat airways.
Topics: Animals; Animals, Newborn; Capsaicin; Denervation; Epithelium; Inflammation; Lung Diseases; Male; Mucous Membrane; Mycoplasma Infections; Neovascularization, Pathologic; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred F344; Substance P; Trachea | 1996 |
Endogenous substance P mediates cold water stress-induced increase in interleukin-6 secretion from peritoneal macrophages.
Topics: Analgesics; Animals; Ascitic Fluid; Capsaicin; Cold Temperature; Indoles; Interleukin-6; Isoindoles; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nerve Endings; Peritoneum; Stress, Physiological; Substance P; Water | 1996 |
K252a modulates the expression of nerve growth factor-dependent capsaicin sensitivity and substance P levels in cultured adult rat dorsal root ganglion neurones.
Topics: Animals; Capsaicin; Carbazoles; Cell Size; Cells, Cultured; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression; Indole Alkaloids; Nerve Growth Factors; Neurons; Neurotoxins; Rats; Sensitivity and Specificity; Substance P | 1996 |
Activation of protein kinase C augments peptide release from rat sensory neurons.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Carcinogens; Cells, Cultured; Down-Regulation; Enzyme Activation; Female; Mice; Neurons, Afferent; Neuropeptides; Phorbol 12,13-Dibutyrate; Potassium; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance P | 1996 |
Different modes of sensory neuropeptides and nitric oxide involvement in relaxation of guinea-pig vessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Neurons, Afferent; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Endoperoxides, Synthetic; Receptors, Neurotransmitter; Substance P; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Postvagotomy changes in neurogenic plasma extravasation in rat bronchi.
Topics: Animals; Bronchi; Bronchitis; Capillary Permeability; Capsaicin; Coloring Agents; Evans Blue; Female; Functional Laterality; Indoles; Male; Mucous Membrane; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Substance P; Vagotomy | 1995 |
The effect of intra-articular capsaicin on nerve fibres within the synovium of the rat knee joint.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Immunohistochemistry; Inflammation; Injections, Intra-Articular; Knee Joint; Leukocytes, Mononuclear; Male; Nerve Fibers; Nerve Tissue Proteins; Neuropeptide Y; Neutrophils; Rats; Rats, Wistar; Substance P; Synovial Membrane; Thiolester Hydrolases; Ubiquitin Thiolesterase | 1996 |
[Influences of capsaicin and electroacupuncture at "point" on acetylcholine (ACh) release in the spinal dorsal horn of rats].
Topics: Acetylcholine; Animals; Capsaicin; Cholinesterase Inhibitors; Electroacupuncture; Female; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1995 |
Role of endogenous substance P in ethanol-induced mucosal damage in the rat stomach.
Topics: Animals; Capsaicin; Ethanol; Gastric Mucosa; Immunoenzyme Techniques; Male; Perfusion; Premedication; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Effects of ONO-1078, a leukotriene antagonist, on cardiovascular responses induced by vagal stimulation, capsaicin, and substance P in guinea pigs.
Topics: Animals; Blood Pressure; Capillary Permeability; Capsaicin; Cardiovascular Agents; Chromones; Electric Stimulation; Female; Guinea Pigs; Heart; Male; SRS-A; Substance P; Vagus Nerve | 1995 |
A comparison of morphological effects on the rabbit nasal and sinus mucosa after surgical denervation and topical capsaicin application.
Topics: Administration, Topical; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Cytoplasmic Granules; Denervation; Fluorescent Antibody Technique; Microscopy, Electron; Nasal Mucosa; Neuropeptide Y; Neuropeptides; Paranasal Sinuses; Rabbits; Rhinitis, Allergic, Perennial; Substance P; Trigeminal Nerve; Vasoactive Intestinal Peptide | 1996 |
Intraplantar injection of nerve growth factor into the rat hind paw: local edema and effects on thermal nociceptive threshold.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase Inhibitors; Denervation; Edema; Foot; Histamine; Injections; Male; Mast Cells; Nerve Growth Factors; Neurons, Afferent; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Substance P | 1996 |
[Role of sensory neuropeptides in the responses of pulmonary and cerebral blood vessels to acute hypoxia in rats].
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cerebrovascular Circulation; Hypoxia; Neuropeptides; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasomotor System | 1996 |
Neural circuitry of capsaicin-sensitive afferents innervating submucosal arterioles in guinea pig ileum.
Topics: Animals; Arterioles; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Nerve Fibers; Neural Pathways; Neurons, Afferent; Substance P; Vasodilation | 1996 |
Substance P enhances electrical field stimulation-induced mast cell degranulation in rat trachea.
Topics: Animals; Biphenyl Compounds; Capsaicin; Cell Degranulation; Chymotrypsin; Dose-Response Relationship, Drug; Electric Stimulation; Indomethacin; Male; Mast Cells; Neurokinin A; Neurokinin-1 Receptor Antagonists; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Substance P; Trachea | 1996 |
Action of sensory neurons in an experimental at colitis model of injury and repair.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Colon; Intestinal Diseases; Intestinal Mucosa; Male; Neurons, Afferent; Peroxidase; Rats; Rats, Sprague-Dawley; Substance P; Ulcer; Wound Healing | 1996 |
Capsaicin-induced inhibition of mitogen and interleukin-2-stimulated T cell proliferation: its reversal by in vivo substance P administration.
Topics: Animals; Animals, Newborn; Capsaicin; Cell Division; Concanavalin A; Female; Interleukin-2; Lymphocyte Activation; Male; Mitogens; Neuropeptides; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Spleen; Substance P; T-Lymphocytes | 1996 |
Evidence for release of glutamic acid, aspartic acid and substance P but not gamma-aminobutyric acid from primary afferent fibres in rat spinal cord.
Topics: Afferent Pathways; Animals; Aspartic Acid; Autoradiography; Capsaicin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Cord; Substance P | 1996 |
Effects of adenosine on NANC bronchoconstriction in anaesthetized guinea-pigs.
Topics: Action Potentials; Adenosine; Airway Resistance; Anesthesia, Intravenous; Animals; Autonomic Nervous System; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Substance P; Vagus Nerve | 1996 |
Neuropeptide- and capsaicin-induced histamine release in skin monitored with the microdialysis technique.
Topics: Adult; Aged; Calcitonin Gene-Related Peptide; Capsaicin; Female; Histamine Release; Humans; Male; Microdialysis; Middle Aged; Neuropeptides; Skin; Substance P; Vasoactive Intestinal Peptide | 1996 |
Calcitonin gene-related peptide innervation of the rat hepatobiliary system.
Topics: Animals; Bile Ducts; Calcitonin Gene-Related Peptide; Capsaicin; Female; Liver; Male; Neurons; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema.
Topics: Animals; Binding Sites; Capsaicin; Dipeptides; Disease Models, Animal; Ear Diseases; Edema; Indoles; Injections, Intravenous; Lethal Dose 50; Male; Mice; Piperidines; Quinuclidines; Receptors, Tachykinin; Skin; Stereoisomerism; Structure-Activity Relationship; Substance P | 1996 |
Spinally-mediated behavioural responses evoked by intrathecal high-dose morphine: possible involvement of substance P in the mouse spinal cord.
Topics: Animals; Behavior, Animal; Capsaicin; Cystamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hormone Antagonists; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Narcotic Antagonists; Narcotics; Somatostatin; Spinal Cord; Substance P; Tachykinins | 1996 |
Antagonism of cholinergic nerve-mediated contractions by the sensory nerve inhibitory system in rat bronchi.
Topics: Acetylcholine; Analgesics; Animals; Bronchi; Capsaicin; Cyclooxygenase Inhibitors; Electric Stimulation; Epithelium; In Vitro Techniques; Indoles; Isoindoles; Male; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Parasympathetic Nervous System; Prostaglandins; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Co-expression of nociceptor properties in dorsal root ganglion neurons from the adult rat in vitro.
Topics: Action Potentials; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Immunohistochemistry; Male; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Blockade of capsaicin-induced reduction of GABA-immunoreactivity by spantide in cat spinal superficial dorsal horn.
Topics: Analgesics; Animals; Capsaicin; Cats; gamma-Aminobutyric Acid; Image Processing, Computer-Assisted; Immunohistochemistry; Interneurons; Nerve Fibers; Neurons, Afferent; Presynaptic Terminals; Spinal Cord; Substance P | 1996 |
Effects of omega-conotoxin GVIA on the activation of capsaicin-sensitive afferent sensory nerves in guinea pig airway tissues.
Topics: Animals; Bronchoconstriction; Calcium Channel Blockers; Capsaicin; Guinea Pigs; Lung; Male; Mollusk Venoms; Muscle Contraction; Muscle, Smooth; omega-Conotoxin GVIA; Peptides; Permeability; Substance P | 1996 |
Exogenous but not endogenous substance P releases histamine from isolated human skin fragments.
Topics: Capsaicin; Histamine Release; Humans; Male; Skin; Stem Cell Factor; Substance P | 1995 |
Capsaicin-sensitive nerves and endurance exercise in the rat.
Topics: Adrenal Medulla; Animals; Animals, Newborn; Blood Glucose; Capsaicin; Catecholamines; Male; Nerve Fibers; Physical Endurance; Physical Exertion; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Effects of capsaicin on detrusor contractility of rats: an in vivo and isolated whole bladder study.
Topics: Administration, Intravesical; Animals; Capsaicin; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Substance P; Urinary Bladder; Urinary Retention | 1996 |
Depletion of vasoactive intestinal peptide and substance P in parotid glands of atropinized rats during reflex secretion.
Topics: Adrenergic Antagonists; Animals; Atropine; Body Weight; Capsaicin; Diet; Female; Neuropeptide Y; Organ Size; Parotid Gland; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Reflex; Substance P; Sympathectomy; Vasoactive Intestinal Peptide | 1996 |
Participation of serotonin in capsaicin-induced mouse ear edema.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Capsaicin; Ear Diseases; Edema; Male; Mice; Mice, Inbred Strains; Serotonin; Substance P | 1995 |
Substance P and capsaicin-induced mechanical hyperalgesia in the rat knee joint; the involvement of bradykinin B1 and B2 receptors.
Topics: Animals; Capsaicin; Female; Hyperalgesia; Knee Joint; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Substance P | 1996 |
Effects of hCGRP 8-37 and the NK1-receptor antagonist SR 140.333 on capsaicin-evoked vasodilation in the pig nasal mucosa in vivo.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Female; Heart Rate; Male; Nasal Cavity; Nasal Mucosa; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinuclidines; Regional Blood Flow; Substance P; Swine; Vasodilation | 1996 |
Neuropeptide Y Y2 receptor-mediated attenuation of neurogenic plasma extravasation acting through pertussis toxin-sensitive mechanisms.
Topics: Animals; Capsaicin; Dura Mater; Electric Stimulation; Extravasation of Diagnostic and Therapeutic Materials; Iodine Radioisotopes; Male; Neuropeptide Y; Peptide Fragments; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Second Messenger Systems; Sensitivity and Specificity; Serum Albumin, Bovine; Stimulation, Chemical; Substance P; Trigeminal Ganglion; Virulence Factors, Bordetella | 1996 |
Inhibitory effect of glycyrrhetinic acid derivatives on capsaicin-induced ear edema in mice.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Capsaicin; Dose-Response Relationship, Drug; Edema; Glycyrrhetinic Acid; Linear Models; Male; Mice; Mice, Inbred Strains; Substance P | 1996 |
Influence of the neurotoxin capsaicin on rat pancreatic islets in culture, and on the pancreatic islet blood flow of rats.
Topics: Animals; Blood Glucose; Calcitonin Gene-Related Peptide; Capsaicin; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Substance P | 1996 |
Oxygen radicals in the nonvagal component of noncholinergic airway constriction.
Topics: Animals; Antioxidants; Autonomic Nervous System; Body Weight; Bronchi; Bronchoconstriction; Capsaicin; Catalase; Cyclic N-Oxides; Guinea Pigs; Lung; Neprilysin; Nitrogen Oxides; Reactive Oxygen Species; Respiratory Function Tests; Spin Labels; Substance P; Superoxide Dismutase; Vagotomy | 1996 |
Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum.
Topics: Animals; Bacterial Toxins; Capsaicin; Clostridioides difficile; Enterotoxins; Female; Ileum; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P | 1996 |
[Capsaicin-induced corneal epithelial changes in rats].
Topics: Animals; Animals, Newborn; Capsaicin; Cornea; Epithelial Cells; Epithelium; Immunohistochemistry; Rats; Rats, Wistar; Substance P | 1996 |
Role of tachykinins in enhancement of bradykinin-induced bronchoconstriction by captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Bradykinin; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Male; Neurokinin A; Peptides, Cyclic; Piperidines; Substance P | 1996 |
Role of substance P and neurokinin A in toluene diisocyanate-induced increased airway responsiveness in rabbits.
Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Animals; Bronchi; Bronchoconstriction; Capsaicin; Disease Models, Animal; Lung Diseases; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Occupational Diseases; Rabbits; Receptors, Neurokinin-2; Substance P; Toluene 2,4-Diisocyanate; Trachea | 1996 |
Nitric oxide mediates capsaicin-induced increase in cochlear blood flow.
Topics: Animals; Capsaicin; Cochlea; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Injections, Intravenous; Laser-Doppler Flowmetry; Male; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Substance P | 1996 |
The role of substance P in myocardial dysfunction during ischemia and reperfusion.
Topics: Analgesics; Animals; Capsaicin; Guinea Pigs; Heart Rate; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Piperidines; Substance P; Ventricular Dysfunction, Left | 1996 |
Modulation of cortical acetylcholine release by serotonin: the role of substance P interneurons.
Topics: Acetylcholine; Animals; Capsaicin; Hippocampus; Humans; Indoles; Isoindoles; Neurokinin-1 Receptor Antagonists; Pindolol; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Substance P; Tetrodotoxin | 1996 |
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.
Topics: Albumins; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillary Permeability; Capsaicin; Captopril; Collagenases; Dose-Response Relationship, Drug; Edema; Glycopeptides; Hindlimb; Indoles; Inflammation; Isoindoles; Male; Matrix Metalloproteinase Inhibitors; Methysergide; Neurokinin-1 Receptor Antagonists; Oligopeptides; Organ Size; Protease Inhibitors; Rats; Rats, Wistar; Serotonin Antagonists; Substance P | 1996 |
Anatomical and electrophysiological comparison of the sensory innervation of bronchial and tracheal parasympathetic ganglion neurons.
Topics: Animals; Antibody Specificity; Axons; Bronchi; Capsaicin; Electrophysiology; Evoked Potentials, Somatosensory; Ganglia, Parasympathetic; Guinea Pigs; Male; Neurons, Afferent; Presynaptic Terminals; Substance P; Trachea | 1996 |
Facilitation by substance P and inhibition by (+)-tubocurarine of the 5-HT3 receptor-mediated Bezold-Jarisch reflex in rats.
Topics: Animals; Capsaicin; Drug Interactions; Heart Rate; Male; Neuromuscular Nondepolarizing Agents; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reflex; Substance P; Tubocurarine | 1996 |
Systemic capsaicin in the adult rat differentially affects gene expression for neuropeptides and neurotrophin receptors in primary sensory neurons.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Gene Expression; Immunohistochemistry; In Situ Hybridization; Male; Microscopy, Electron; Nerve Fibers, Myelinated; Neurons, Afferent; Neuropeptides; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, Nerve Growth Factor; Substance P | 1997 |
The involvement of sensory neuropeptides in toluene diisocyanate-induced tracheal hyperreactivity in the mouse airways.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Indoles; Isoindoles; Isometric Contraction; Male; Mice; Mice, Inbred BALB C; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Neuropeptides; Respiratory Hypersensitivity; Skin; Substance P; Tachykinins; Toluene 2,4-Diisocyanate; Tracheal Diseases | 1996 |
Morphological and functional evidence against a sensory and sympathetic origin of nitric oxide synthase-containing nerves in the rat lower urinary tract.
Topics: Acetylcholinesterase; Animals; Antibody Specificity; Arginine Vasopressin; Calcitonin Gene-Related Peptide; Capsaicin; Enzyme Inhibitors; Female; Gold Colloid; Microscopy, Electron; Molsidomine; Neurons, Afferent; Neuropeptide Y; Nitric Oxide Synthase; Nitroarginine; Oxidopamine; Rats; Rats, Sprague-Dawley; Substance P; Sympathectomy, Chemical; Sympathetic Fibers, Postganglionic; Sympatholytics; Tyrosine 3-Monooxygenase; Urethra; Urothelium; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Replication-deficient adenoviral vector for gene transfer potentiates airway neurogenic inflammation.
Topics: Adenoviruses, Human; Animals; Capillary Permeability; Capsaicin; Dexamethasone; Ficusin; Gene Transfer Techniques; Genetic Vectors; Glucocorticoids; Hot Temperature; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Photosensitizing Agents; Piperidines; Protein Denaturation; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Respiratory System; Substance P; Ultraviolet Rays | 1997 |
Evidence for functional responses to sensory nerve stimulation of rat small mesenteric veins.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Male; Mesenteric Veins; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Substance P; Vasodilation | 1997 |
Low but not high rate noxious radiant skin heating evokes a capsaicin-sensitive increase in spinal cord dorsal horn release of substance P.
Topics: Animals; Behavior, Animal; Capsaicin; Decerebrate State; Hot Temperature; Male; Nociceptors; Pain; Radioimmunoassay; Rats; Rats, Wistar; Skin; Spinal Cord; Substance P | 1997 |
Ocular inflammation induced by electroconvulsive treatment: contribution of nitric oxide and neuropeptides mobilized from C-fibres.
Topics: Animals; Aqueous Humor; Capsaicin; Electroconvulsive Therapy; Eye Diseases; Inflammation; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Receptors, Tachykinin; Substance P | 1997 |
Substance P as a mediator of colonic secretory reflexes.
Topics: Animals; Capsaicin; Colon; Electric Conductivity; Guinea Pigs; Intestinal Mucosa; Male; Physical Stimulation; Receptors, Neurokinin-1; Reflex; RNA, Messenger; Submucous Plexus; Substance P; Tachykinins; Tetrodotoxin | 1997 |
Glyceryl nonivamide, a nonpungent analogue of capsaicin, enhances substance P release and renal function in rats.
Topics: Absorption; Animals; Blood Pressure; Capsaicin; Cerebrospinal Fluid; Dose-Response Relationship, Drug; Drug Interactions; Glomerular Filtration Rate; Glycerol; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Kidney; Kidney Tubules; Male; Neurons, Afferent; Potassium; Radioimmunoassay; Rats; Rats, Wistar; Sodium; Software; Spinal Cord; Substance P; Urinalysis | 1997 |
Enrichment of the fraction of nociceptive neurones in cultures of primary sensory neurones.
Topics: Animals; Animals, Newborn; Antibody Specificity; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cell Separation; Cell Size; Cells, Cultured; Ganglia, Spinal; Immunohistochemistry; Microscopy, Confocal; Neurons, Afferent; Nociceptors; Rats; Rats, Wistar; Substance P | 1997 |
Effect of capsaicin treatment or inferior alveolar nerve resection on dentine formation and calcitonin gene-related peptide- and substance P-immunoreactive nerve fibres in rat molar pulp.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coloring Agents; Dental Pulp; Dentin; Dentinogenesis; Female; Gingiva; Immunohistochemistry; Mandibular Nerve; Molar; Nerve Fibers; Neurons, Afferent; Periodontium; Rats; Rats, Sprague-Dawley; Substance P; Triazines | 1996 |
Pulmonary response to inhaled antigen: neuroimmune interactions promote the recruitment of dendritic cells to the lung and the cellular immune response to inhaled antigen.
Topics: Administration, Inhalation; Animals; Antigens; Capsaicin; Cell Movement; Dendritic Cells; Female; Immunity, Cellular; Lung; Muramidase; Rats; Rats, Inbred Lew; Substance P | 1997 |
Localization of leukaemia inhibitory factor to airway epithelium and its amplification of contractile responses to tachykinins.
Topics: Animals; Capsaicin; Carbachol; Epithelium; Female; Growth Inhibitors; Guinea Pigs; Humans; Immunohistochemistry; In Vitro Techniques; Interleukin-6; Isoproterenol; Leukemia Inhibitory Factor; Lymphokines; Muscle Contraction; Neurokinin A; Substance P; Trachea | 1997 |
Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas.
Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Coloring Agents; Digestive System; Evans Blue; Indoles; Mice; Mice, Inbred Strains; Organometallic Compounds; Pancreas; Plasma; Substance P; Venules | 1997 |
Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Ileum; In Vitro Techniques; Neurokinin A; Perfusion; Phentolamine; Substance P; Swine; Tachykinins | 1997 |
Involvement of both L- and N-type voltage-dependent Ca2+ channels in KCl- and veratridine-evoked transmitter release from non-adrenergic, non-cholinergic nerves in the rabbit iris sphincter muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Atropine; Calcium Channel Blockers; Calcium Channels; Capsaicin; Iris; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicardipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Potassium Chloride; Rabbits; Receptors, Tachykinin; Sodium Channels; Spider Venoms; Substance P; Synaptic Transmission; Veratridine | 1997 |
Pre- and postjunctional inhibitory effects of fenspiride on guinea-pig bronchi.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Nerve Fibers; Neurokinin A; Neuropeptides; Peptide Fragments; Propranolol; Spiro Compounds; Substance P | 1997 |
Effects of several denervation procedures on distribution of calcitonin gene-related peptide and substance P immunoreactive in rat stomach.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Mucosa; Male; Nerve Fibers; Oxidopamine; Rats; Rats, Sprague-Dawley; Stomach; Substance P; Sympathectomy; Sympathectomy, Chemical; Vagotomy | 1997 |
Comparative study of the effects of capsaicin on the contractility of normal and spinal cord injured human bladders.
Topics: Analgesics; Bethanechol; Capsaicin; Electric Stimulation; Humans; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Spinal Cord Injuries; Substance P; Urinary Bladder | 1997 |
PAMP is a novel inhibitor of the tachykinin release in the airway of guinea pigs.
Topics: Adrenomedullin; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Capsaicin; Guinea Pigs; Isoproterenol; Male; Neurokinin A; Peptide Fragments; Peptides; Proteins; Substance P | 1997 |
Inhibition of substance P release from spinal cord tissue after pretreatment with capsaicin does not mediate the antinociceptive effect of capsaicin in adult mice.
Topics: Animals; Capsaicin; Drug Evaluation, Preclinical; Injections, Spinal; Male; Mice; Pain; Perfusion; Spinal Cord; Substance P | 1997 |
Antinociception induced by civamide, an orally active capsaicin analogue.
Topics: Administration, Oral; Analgesics; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Hot Temperature; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substance P | 1997 |
Tachykinins do not cause plasma leakage in the rabbit trachea.
Topics: Animals; Capsaicin; Male; Pulmonary Circulation; Rabbits; Substance P; Sulfites; Tachykinins; Trachea | 1997 |
Tachykinin antagonist FK224 inhibits neurokinin A-, substance P- and capsaicin-induced human bronchial contraction.
Topics: Acetylcholine; Adult; Aged; Bronchi; Capsaicin; Glycopeptides; Histamine; Humans; In Vitro Techniques; Leukotriene D4; Middle Aged; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Protease Inhibitors; Receptors, Tachykinin; Substance P; Tachykinins | 1997 |
Synergistic interactions between neuropeptide and histamine on the capillary permeability in rat skin: evaluation by reflectance spectrophotometry.
Topics: Administration, Cutaneous; Animals; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Cimetidine; Diphenhydramine; Drug Synergism; Histamine; Histamine Antagonists; Male; Neuropeptides; Rats; Rats, Wistar; Skin; Spectrophotometry; Substance P | 1997 |
The use of capsaicin in herpes zoster ophthalmicus neuralgia.
Topics: Administration, Topical; Aged; Capsaicin; Female; Follow-Up Studies; Herpes Zoster Ophthalmicus; Humans; Male; Middle Aged; Neuralgia; Ointments; Substance P | 1997 |
Effect of capsaicin on substance P and nerve growth factor in adjuvant arthritic rats.
Topics: Animals; Arthritis, Experimental; Capsaicin; Ganglia, Spinal; Male; Nerve Growth Factors; Protein Precursors; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Reference Values; RNA, Messenger; Sciatic Nerve; Skin; Substance P; Tachykinins; Transcription, Genetic | 1997 |
Plasma extravasation and neuropeptide release in human skin as measured by intradermal microdialysis.
Topics: Adult; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Forearm; Histamine; Humans; Inflammation; Iontophoresis; Microdialysis; Pain; Skin; Substance P; Time Factors | 1997 |
Sensory nerve-mediated inhibitory responses in airways of F344 rats.
Topics: Analgesics; Animals; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Male; Meclofenamic Acid; Muscle Contraction; Muscle Relaxation; Neural Inhibition; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred F344; Substance P; Trachea | 1997 |
Afferent C-fibres release substance P and glutamate.
Topics: Animals; Capsaicin; Glutamic Acid; Male; Nerve Fibers; Neurons, Afferent; Potassium Chloride; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Time Factors | 1997 |
The epidermal nerve fibre network: characterization of nerve fibres in human skin by confocal microscopy and assessment of racial variations.
Topics: Asian People; Blister; Capsaicin; Epidermis; Humans; Microscopy, Confocal; Nerve Fibers; Nerve Tissue Proteins; Radioimmunoassay; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; White People | 1997 |
A single capsaicin injection partially depletes neuropeptides but does not ameliorate inflammation severity in established feline antigen induced arthritis.
Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Immunohistochemistry; Injections, Intra-Articular; Knee Joint; Substance P; Synovial Membrane; Synovitis | 1997 |
Effects of the immunosuppressant cyclosporin A on neurotransmitter release from peripheral non-adrenergic, non-cholinergic nerves.
Topics: Animals; Atropine; Calcium Channel Blockers; Capsaicin; Cyclosporine; Dipeptides; Immunosuppressive Agents; Indoles; Iris; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Rabbits; Sodium Channel Blockers; Substance P | 1997 |
Role of nitric oxide in the dilator actions of capsaicin-sensitive nerves in the rabbit coronary circulation.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Circulation; Coronary Vessels; Female; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Perfusion; Rabbits; Substance P; Vasodilator Agents | 1997 |
Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor.
Topics: Animals; Capsaicin; Cell Membrane; Cells, Cultured; Fluorescent Antibody Technique; Hyperalgesia; Immunotoxins; Injections, Spinal; N-Glycosyl Hydrolases; Neurons; Pain; Pain Management; Pain Measurement; Plant Proteins; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Signal Transduction; Spinal Cord; Substance P | 1997 |
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Electric Stimulation; Endocytosis; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Long-Term Potentiation; Male; Microscopy, Confocal; Microscopy, Fluorescence; Models, Neurological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1997 |
Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cord.
Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; GABA Antagonists; GABA-B Receptor Antagonists; Hot Temperature; Hyperalgesia; Hypesthesia; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Nerve Growth Factors; Neurotrophin 3; Organophosphorus Compounds; Pain; Pain Threshold; Perfusion; Pressure; Rats; Rats, Wistar; Secretory Rate; Single-Blind Method; Spinal Cord; Substance P | 1997 |
Plasma protein extravasation induced in the rat dura mater by stimulation of the parasympathetic sphenopalatine ganglion.
Topics: Acetylcholine; Afferent Pathways; Animals; Atropine; Axons; Blood Pressure; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Disease Models, Animal; Dura Mater; Electric Stimulation; Exudates and Transudates; Ganglia, Parasympathetic; Inflammation; Injections, Intra-Arterial; Male; Migraine Disorders; Neurons, Afferent; Parasympathetic Fibers, Postganglionic; Parasympathomimetics; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serum Albumin, Bovine; Substance P | 1997 |
Neurogenic vasoreactive response of human internal thoracic artery smooth muscle.
Topics: Acetylcholine; Adult; Aged; Capsaicin; Endothelium, Vascular; Humans; Isometric Contraction; Middle Aged; Muscle, Smooth, Vascular; Nerve Fibers; Nitroprusside; Substance P; Thoracic Arteries; Vasoconstriction; Vasodilator Agents | 1997 |
Neurokinin A-LI release after antigen challenge in guinea-pig bronchial tubes: influence of histamine and bradykinin.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Ovalbumin; Pyrilamine; Substance P; Trachea | 1997 |
Antinociceptive properties of the hydroalcoholic extract and preliminary study of a xanthone isolated from Polygala cyparissias (Polygalaceae).
Topics: Abdominal Pain; Acetic Acid; Analgesia; Analgesics; Animals; Aspirin; Bradykinin; Capsaicin; Ethanol; Hot Temperature; Male; Pain; Pain Measurement; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Substance P; Water; Xanthenes; Xanthones | 1997 |
Intraintestinal capsaicin transiently reduces CGRP-like immunoreactivity in rat submucosal plexus.
Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide; Capsaicin; Eating; Intestinal Mucosa; Male; Myenteric Plexus; Nerve Fibers; Neurons, Afferent; Oleic Acid; Rats; Rats, Sprague-Dawley; Substance P; Time Factors | 1997 |
Cellular pathways mediating tachykinin-evoked secretomotor responses in guinea pig ileum.
Topics: Animals; Capsaicin; Electric Stimulation; Evoked Potentials; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Membrane Potentials; Muscle, Smooth; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tachykinins | 1997 |
Mechanism of capsaicin-induced relaxation in equine tracheal smooth muscle.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Charybdotoxin; Chymotrypsin; Epithelial Cells; Horses; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons, Afferent; Neuropeptides; Nitric Oxide; Nitroarginine; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Substance P; Trachea; Vasoactive Intestinal Peptide | 1997 |
Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Asthma; Capsaicin; Cells, Cultured; Coculture Techniques; Cytochalasin B; Enzyme-Linked Immunosorbent Assay; Eosinophils; Ganglia, Spinal; Humans; Myelin Basic Protein; N-Formylmethionine Leucyl-Phenylalanine; Neurons; Platelet Activating Factor; Polylysine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic, Seasonal; Substance P; Tissue Extracts | 1997 |
Effects of tachykinins and capsaicin on the mechanical and electrical activity of the guinea-pig isolated trachea.
Topics: Animals; Benzamides; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Potassium Channel Blockers; Quinuclidines; Receptors, Neurokinin-2; Substance P; Tachykinins; Tetraethylammonium; Trachea | 1997 |
Capsaicin stimulates release of substance P from dorsal root ganglion neurons via two distinct mechanisms.
Topics: Animals; Botulinum Toxins, Type A; Calcium; Capsaicin; Cells, Cultured; Egtazic Acid; Embryo, Mammalian; Ganglia, Spinal; Kinetics; Neurons; Potassium Chloride; Rats; Substance P | 1997 |
Inhibitory effect of capsaicin on detrusor contractility: further study in the presence of ganglionic blocker and neurokinin receptor antagonist in the rat urinary bladder.
Topics: Administration, Intravesical; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Ganglionic Blockers; Hexamethonium; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Substance P; Urinary Bladder | 1997 |
CGRP, but not substance P, induces an increased negativity of the interstitial fluid pressure in rat trachea.
Topics: Animals; Blood Pressure; Body Fluids; Calcitonin Gene-Related Peptide; Capsaicin; Feedback; Injections, Intravenous; Pressure; Rats; Rats, Wistar; Substance P; Trachea | 1997 |
Lower oesophageal sphincter responses to noxious oesophageal chemical stimuli in the ferret: involvement of tachykinin receptors.
Topics: Animals; Capsaicin; Electric Stimulation; Esophagogastric Junction; Female; Ferrets; Gastric Acid; Gastroesophageal Reflux; Male; Manometry; Neurotransmitter Agents; Receptors, Tachykinin; Stimulation, Chemical; Substance P; Sympathetic Nervous System; Tachykinins; Vagus Nerve | 1997 |
Role of 5-hydroxytryptamine and mast cells in the tachykinin-induced contraction of rat trachea in vitro.
Topics: Animals; Bronchoconstriction; Capsaicin; In Vitro Techniques; Male; Mast Cells; Neurokinin A; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Serotonin; Substance P; Tachykinins; Trachea | 1997 |
Evidence for non-adrenergic non-cholinergic contractile responses in bovine and swine trachea.
Topics: Animals; Bronchoconstriction; Capsaicin; Cattle; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle, Smooth; Substance P; Swine; Trachea | 1997 |
Tachykinins may mediate capsaicin-induced, but not vagally induced motility in porcine antrum.
Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Pyloric Antrum; Receptors, Neurokinin-2; Substance P; Swine; Tachykinins; Vagus Nerve | 1997 |
Effects of capsaicin in temporomandibular joint arthritis in rats.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; Denervation; Disease Models, Animal; Female; Mandibular Nerve; Neurons, Afferent; Neuropeptide Y; Neurotoxins; Nontuberculous Mycobacteria; Radioimmunoassay; Rats; Rats, Inbred Lew; Substance P; Sympathetic Nervous System; Temporomandibular Joint; Temporomandibular Joint Disorders; Trigeminal Ganglion | 1997 |
Hyperinnervation of the airways in transgenic mice overexpressing nerve growth factor.
Topics: Airway Resistance; Animals; Capsaicin; Catecholamines; Disease Models, Animal; Gene Expression; Lung; Mice; Mice, Transgenic; Nerve Growth Factors; Neurons, Afferent; Oxidopamine; Promoter Regions, Genetic; Proteins; Rats; RNA, Messenger; Substance P; Uteroglobin | 1998 |
Endothelium-dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store.
Topics: Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Mesenteric Arteries; Muscle Relaxation; Nerve Fibers; Neurons, Afferent; Nitric Oxide; Rabbits; Sensitivity and Specificity; Substance P; Thionucleotides; Ultraviolet Rays; Vasodilation | 1998 |
Role of substance P in experimental allergic conjunctivitis in guinea pigs.
Topics: Animals; Capillary Permeability; Capsaicin; Conjunctiva; Conjunctivitis, Allergic; Dipeptides; Disease Models, Animal; Guinea Pigs; Histamine; Indoles; Male; Mast Cells; Ovalbumin; p-Methoxy-N-methylphenethylamine; Serine Proteinase Inhibitors; Substance P; Tears | 1997 |
Characterization of unmyelinated axons uniting epidermal and dermal immune cells in primate and murine skin.
Topics: Adult; Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Clathrin; Cytoplasmic Granules; Epidermal Cells; Epidermis; Humans; Immunoenzyme Techniques; Langerhans Cells; Macaca fascicularis; Male; Mast Cells; Mice; Mice, Inbred Strains; Microscopy, Confocal; Neural Cell Adhesion Molecules; Skin; Skin Transplantation; Substance P | 1998 |
Effects of carbamazepine on plasma extravasation and bronchoconstriction induced by substance P, capsaicin, acetaldehyde and histamine in guinea-pig lower airways.
Topics: Acetaldehyde; Animals; Anticonvulsants; Bronchoconstriction; Capillary Permeability; Capsaicin; Carbamazepine; Evans Blue; Guinea Pigs; Histamine; Male; Pharmaceutical Preparations; Receptors, Neurokinin-1; Substance P; Trachea | 1998 |
Role of sensory innervation and mast cells in neurogenic plasma protein exudation into the airway lumen.
Topics: Analysis of Variance; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Exudates and Transudates; Histamine; Inflammation; Mast Cells; Neuropeptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Substance P; Trachea; Vagus Nerve | 1997 |
Human monocytes and macrophages express substance P and neurokinin-1 receptor.
Topics: Adult; Capsaicin; Humans; Macrophages; Monocytes; Receptors, Neurokinin-1; RNA, Messenger; Substance P | 1997 |
Edema formation in the rat larynx.
Topics: Animals; Capsaicin; Cell Degranulation; Injections, Intravenous; Laryngeal Edema; Larynx; Male; Mast Cells; Microscopy, Electron; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Substance P | 1998 |
Effects of endotracheal intubation on airway neuropeptide content, arterial oxygenation and lung volumes in anaesthetized rats.
Topics: Anesthesia, General; Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Intubation, Intratracheal; Lung Volume Measurements; Neurokinin A; Neuropeptides; Oxygen; Pulmonary Gas Exchange; Rats; Rats, Sprague-Dawley; Respiratory System; Substance P; Vasoactive Intestinal Peptide | 1998 |
Involvement of tachykinin NK1 receptors in plasma protein extravasation induced by tachykinins in the guinea pig upper airways.
Topics: Animals; Antigens; Blood Proteins; Capsaicin; Dextrans; Dipeptides; Extravasation of Diagnostic and Therapeutic Materials; Fluorescein-5-isothiocyanate; Glycopeptides; Guinea Pigs; Indoles; Male; Nasal Mucosa; Neurokinin A; Neurokinin-1 Receptor Antagonists; Olfactory Receptor Neurons; Peptide Fragments; Peptides, Cyclic; Protease Inhibitors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Rhinitis; Substance P | 1997 |
Afferent reinnervation after lung transplantation in the rat.
Topics: Animals; Bacterial Infections; Bradycardia; Calcitonin Gene-Related Peptide; Capsaicin; Cough; Denervation; Fluorescent Dyes; Follow-Up Studies; Immunohistochemistry; Incidence; Lung; Lung Transplantation; Male; Nerve Fibers; Nerve Regeneration; Neurons, Afferent; Nodose Ganglion; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Inbred Lew; Reflex; Stilbamidines; Substance P; Time Factors; Transplantation, Isogeneic; Vagus Nerve | 1998 |
Activation of non-adrenergic non-cholinergic inhibitory pathways by endogenous and exogenous tachykinins in the ferret lower oesophageal sphincter.
Topics: Animals; Capsaicin; Electric Stimulation; Esophagogastric Junction; Female; Ferrets; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Neurokinin A; Neurokinin-1 Receptor Antagonists; Nitroarginine; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Substance P; Tachykinins; Tetrodotoxin | 1998 |
Ultrastructural identification of substance P containing nerves in the guinea pig trabecular meshwork.
Topics: Animals; Autonomic Nervous System; Capsaicin; Guinea Pigs; Male; Microscopy, Immunoelectron; Substance P; Sympathectomy, Chemical; Trabecular Meshwork | 1998 |
Attenuation of isocapnic hyperpnoea-induced guinea-pig bronchoconstriction by chronic hypoxia.
Topics: Animals; Bronchial Spasm; Capsaicin; Carbon Dioxide; Chronic Disease; Forced Expiratory Volume; Guinea Pigs; Hypoxia; Lung; Male; Neprilysin; Pulmonary Ventilation; Respiration; Substance P; Trachea | 1998 |
Inhibition of nociceptin on sensory neuropeptide release and mast cell-mediated plasma extravasation in rats.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Coloring Agents; Denervation; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Female; Hindlimb; Mast Cells; Nociceptin; Opioid Peptides; Peptides; Rats; Rats, Wistar; Somatostatin; Substance P | 1998 |
Human lymphocytes express substance P and its receptor.
Topics: Adult; Autocrine Communication; Blotting, Southern; Capsaicin; Gene Expression; Humans; Lymphocytes; Paracrine Communication; Polymerase Chain Reaction; Protein Precursors; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tachykinins | 1998 |
[Effect of adenosine and its analogues on microvascular leakage in the rat trachea].
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Male; Neurons, Afferent; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substance P; Tachykinins; Trachea; Vasodilator Agents | 1998 |
Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Cell Line; Dogs; Histocytochemistry; Immunohistochemistry; Male; Nerve Endings; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Rhizotomy; Spinal Cord; Substance P | 1998 |
Enhancing effect of dimethyl sulfoxide on nociceptive transmission in isolated spinal cord of newborn rat.
Topics: Animals; Animals, Newborn; Capsaicin; Cholinesterases; Dimethyl Sulfoxide; Electric Stimulation; Excitatory Postsynaptic Potentials; Humans; Infant, Newborn; Nerve Fibers; Neurons, Afferent; Nociceptors; Osmotic Pressure; Pain; Potassium Channel Blockers; Rats; Rats, Wistar; Reflex; Spinal Cord; Spinal Nerve Roots; Substance P | 1998 |
Radioimmunoassay of substance P in lung perfusate.
Topics: Animals; Capsaicin; Lung; Perfusion; Rabbits; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Substance P; Tyrosine | 1998 |
Sensory nerves affect the recruitment and differentiation of rat periovarian brown adipocytes during cold acclimation.
Topics: Acclimatization; Adipocytes; Adipose Tissue, Brown; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Count; Cell Differentiation; Cold Temperature; Female; Microscopy, Electron; Neurons, Afferent; Neuropeptides; Ovary; Rats; Rats, Sprague-Dawley; Substance P; Temperature | 1998 |
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
Topics: Abdominal Pain; Acetic Acid; Animals; Bradykinin; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Male; Mice; Motor Activity; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Sesquiterpenes; Substance P; Zymosan | 1998 |
The effects of SDZ NKT 343, a potent NK1 receptor antagonist, on cutaneous responses of primate spinothalamic tract neurones sensitized by intradermal capsaicin injection.
Topics: Action Potentials; Animals; Capsaicin; Electrophysiology; Haplorhini; Injections, Intradermal; Male; Naphthalenes; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Proline; Skin; Spinothalamic Tracts; Substance P | 1998 |
Extrinsic denervation increases myenteric nitric oxide synthase-containing neurons and inhibitory neuromuscular transmission in guinea pig.
Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Male; Muscle Denervation; Muscle, Smooth; Myenteric Plexus; Neural Inhibition; Neuronal Plasticity; Neurons, Afferent; Nitric Oxide Synthase; Nitroprusside; Oxidopamine; Peptide Fragments; Stimulation, Chemical; Substance P; Sulfhydryl Reagents; Sympatholytics; Synaptic Transmission; Vasoactive Intestinal Peptide | 1998 |
[Chemical anatomy of the nociceptive transmission and modulation in the spinal dorsal horn].
Topics: Animals; Capsaicin; Cats; Glutamates; Nerve Fibers; Neurons, Afferent; Nociceptors; Pain; Rats; Rats, Wistar; Spinal Cord; Substance P | 1996 |
Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: correlation with sensory function.
Topics: Adult; Aged; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Epidermis; Female; Humans; Injections, Intradermal; Male; Microscopy, Confocal; Microscopy, Fluorescence; Middle Aged; Nerve Degeneration; Nerve Regeneration; Neurons, Afferent; Sensation; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase | 1998 |
Nociceptin inhibits non-adrenergic non-cholinergic contraction in guinea-pig airway.
Topics: Animals; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuropeptides; Nociceptin; Opioid Peptides; Receptors, Opioid; Substance P | 1998 |
Swimming capacity of mice is increased by oral administration of a nonpungent capsaicin analog, stearoyl vanillylamide.
Topics: Animals; Blood Glucose; Capsaicin; Epinephrine; Fatty Acids, Nonesterified; Injections, Intravenous; Male; Mice; Pain; Physical Exertion; Substance P; Swimming | 1998 |
Acute and chronic effects of capsaicin in perfused rat muscle: the role of tachykinins and calcitonin gene-related peptide.
Topics: Animals; Benzamides; Calcitonin Gene-Related Peptide; Capsaicin; Male; Muscle, Skeletal; Neurokinin A; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Substance P | 1998 |
Effect of ONO-1078, a leukotriene antagonist, on capsaicin- and substance P-induced bronchoconstriction and airway microvascular leakage in guinea pigs.
Topics: Animals; Bronchi; Bronchoconstriction; Capsaicin; Chromones; Female; Guinea Pigs; In Vitro Techniques; Leukotriene C4; Male; Muscle Contraction; Muscle, Smooth; Substance P | 1996 |
Substance P and capsaicin release prostaglandin E2 from rat intrapulmonary bronchi.
Topics: Animals; Bronchi; Capsaicin; Dinoprostone; Epithelial Cells; In Vitro Techniques; Indoles; Isoindoles; Male; Meclofenamic Acid; Models, Biological; Muscle, Smooth; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Substance P | 1998 |
Temperature- and capsaicin-sensitive nerve fibers in brown adipose tissue attenuate thermogenesis in the rat.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Female; Hot Temperature; Nerve Fibers; Norepinephrine; Rats; Rats, Sprague-Dawley; Substance P | 1998 |
NK-3 receptors mediate enhancement of substance P release from capsaicin-sensitive spinal cord afferent terminals.
Topics: Animals; Capsaicin; In Vitro Techniques; Male; Neurons, Afferent; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Spinal Cord; Substance P; Synaptosomes | 1998 |
Neuropeptide regulation of human dermal microvascular endothelial cell ICAM-1 expression and function.
Topics: Capsaicin; Cell Adhesion; Cell Membrane; Cellular Senescence; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Lymphocytes; Microcirculation; Neuropeptides; Receptors, Neurokinin-1; Receptors, Tachykinin; RNA, Messenger; Skin; Substance P | 1998 |
Amiloride-sensitive Na+ channels in pelvic uroepithelium involved in renal sensory receptor activation.
Topics: Amiloride; Animals; Capsaicin; Diuretics; In Situ Hybridization; Kidney; Kidney Pelvis; Neurons, Afferent; Ouabain; Pressure; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sensory Receptor Cells; Sodium Channels; Substance P; Urothelium | 1998 |
Effect of sensory neuropeptides on mucus secretion from cultured goblet cells.
Topics: Animals; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Exocytosis; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Substance P; Trachea | 1998 |
Calcitonin gene-related peptide protects cultured rat gastric mucosal cells.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ethanol; Gastric Mucosa; Indomethacin; Rats; Substance P | 1998 |
Subthreshold concentration of endothelin-1-enhanced, capsaicin-induced bronchoconstriction in anaesthetized guinea-pigs.
Topics: Aerosols; Airway Resistance; Anesthesia; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Guinea Pigs; Male; Neurokinin A; Oligopeptides; Peptides, Cyclic; Piperidines; Substance P | 1998 |
Effects of systemic resiniferatoxin treatment on substance P mRNA in rat dorsal root ganglia and substance P receptor mRNA in the spinal dorsal horn.
Topics: Administration, Topical; Animals; Capsaicin; Diterpenes; Ganglia, Spinal; In Situ Hybridization; Injections, Subcutaneous; Male; Neurokinin-1 Receptor Antagonists; Neurotoxins; Pain Management; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ribonucleases; RNA, Messenger; Spinal Cord; Substance P; Tachykinins | 1999 |
Particulate matter initiates inflammatory cytokine release by activation of capsaicin and acid receptors in a human bronchial epithelial cell line.
Topics: Air Pollutants; Amiloride; Bronchi; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium; Capsaicin; Carbon; Cell Line; Coal Ash; Cytokines; Epithelium; Humans; Hydrogen-Ion Concentration; Interleukin-6; Interleukin-8; Neurokinin-1 Receptor Antagonists; Particulate Matter; Receptors, Calcitonin Gene-Related Peptide; Receptors, Drug; Receptors, Neurokinin-1; Substance P; Tumor Necrosis Factor-alpha | 1999 |
NMDA receptor activation modulates evoked release of substance P from rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Capsaicin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1998 |
Chelation of zinc in the extracellular area of the spinal cord, using ethylenediaminetetraacetic acid disodium-calcium salt or dipicolinic acid, inhibits the antinociceptive effect of capsaicin in adult mice.
Topics: Acetic Acid; Animals; Capsaicin; Chelating Agents; Drug Interactions; Edetic Acid; Extracellular Space; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain Measurement; Peptide Fragments; Picolinic Acids; Spinal Cord; Substance P; Zinc | 1999 |
Effects of a tachykinin NK3 receptor antagonist, SR 142801, studied in isolated neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Neurokinin B; Neurons, Afferent; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-3; Spinal Cord; Spinal Nerve Roots; Substance P | 1998 |
VCAM-1 expression on human dermal microvascular endothelial cells is directly and specifically up-regulated by substance P.
Topics: Capsaicin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Inflammation; Neuroimmunomodulation; RNA, Messenger; Skin; Substance P; T-Lymphocytes; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 1999 |
Dynorphin A increases substance P release from trigeminal primary afferent C-fibers.
Topics: Animals; Animals, Newborn; Capsaicin; Dizocilpine Maleate; Dynorphins; Enkephalin, Leucine; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei | 1999 |
Capsaicin-sensitive C-fiber-mediated protective responses in ozone inhalation in rats.
Topics: Administration, Inhalation; Animals; Antimetabolites; Bromodeoxyuridine; Capsaicin; Epithelium; Female; Lung; Nasal Cavity; Nerve Fibers; Oxidants, Photochemical; Ozone; Pregnancy; Rats; Rats, Wistar; Respiratory Mechanics; Respiratory System; Substance P; Tidal Volume; Trachea | 1999 |
Neurogenic plasma leakage in mouse airways.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Blood Vessels; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Capsaicin; Captopril; Dose-Response Relationship, Drug; Evans Blue; Glycopeptides; Lung; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Piperidines; Protease Inhibitors; Quinuclidines; Receptors, Neurokinin-2; Skin; Specific Pathogen-Free Organisms; Substance P; Trachea; Urinary Bladder | 1999 |
Intracerebroventricular injection of capsaicin or substance P provokes the micturition reflex in the rat.
Topics: Animals; Brain; Capsaicin; Injections, Intraventricular; Male; Rats; Reflex; Substance P; Tachykinins; Urinary Bladder; Urination | 1998 |
Decreased vascular permeability response to substance P in airways of genetically hypertensive rats.
Topics: Animals; Blood Pressure; Capillary Permeability; Capsaicin; Hypertension; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P | 1999 |
The inhibition of nicotine-evoked relaxation of the guinea-pig isolated basilar artery by some analgesic drugs and progesterone.
Topics: Analgesics; Animals; Aspirin; Basilar Artery; Capsaicin; Dinoprost; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Migraine Disorders; NG-Nitroarginine Methyl Ester; Nicotine; Progesterone; Substance P; Sumatriptan; Vasodilation | 1999 |
Central injections of capsaicin cause antidiuresis mediated through neurokinin-1 receptors in rat hypothalamus and vasopressin release.
Topics: Acetylcholine; Anesthesia; Animals; Atropine; Binding Sites; Biphenyl Compounds; Capsaicin; Diuresis; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Injections, Intraventricular; Male; Microdialysis; Phenoxybenzamine; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; Supraoptic Nucleus; Time Factors; Timolol; Vasopressins | 1999 |
Systemically administered capsazepine prevents the capsaicin-induced functional desensitization and loss of substance P-like immunoreactivity (SP-LI) in guinea-pig bronchi.
Topics: Animals; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Substance P | 1999 |
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Carrageenan; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; In Vitro Techniques; Inflammation; Knee Joint; Male; N-Methylaspartate; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Thromboxane B2 | 1999 |
Patterns of innervation of sympathetic vascular neurons by peptide-containing primary sensory fibers.
Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide; Capsaicin; Enteric Nervous System; Female; Ganglia, Sympathetic; Guinea Pigs; Male; Mesenteric Arteries; Mesenteric Veins; Nerve Fibers; Neurons, Afferent; Nitric Oxide Synthase; Substance P | 1999 |
Cyclosporin A increases tear fluid secretion via release of sensory neurotransmitters and muscarinic pathway in mice.
Topics: Administration, Topical; Animals; Atropine; Capsaicin; Cyclosporine; Female; Immunohistochemistry; Immunosuppressive Agents; Lacrimal Apparatus; Mice; Mice, Inbred BALB C; Muscarinic Agonists; Muscarinic Antagonists; Parasympathetic Nervous System; Pilocarpine; Substance P; Tears | 1999 |
Limitations in using peptide drugs to characterize calcitonin gene-related peptide receptors.
Topics: Animals; Basilar Artery; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Peptide Fragments; Potassium Chloride; Receptors, Calcitonin Gene-Related Peptide; Reproducibility of Results; Substance P; Swine; Vasodilation | 1999 |
Modulatory effect of imetit, a histamine H3 receptor agonist, on C-fibers, cholinergic fibers and mast cells in rabbit lungs in vitro.
Topics: Animals; Capsaicin; Carbachol; Cholinergic Fibers; Drug Interactions; Female; Histamine Agonists; Histamine Release; Imidazoles; In Vitro Techniques; Lung; Male; Mast Cells; Rabbits; Radioimmunoassay; Receptors, Histamine H3; Substance P; Thiourea | 1999 |
Low dose of kyotorphin (tyrosine-arginine) induces nociceptive responses through a substance P release from nociceptor endings.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Endorphins; Male; Mice; Mice, Inbred Strains; Nerve Endings; Neurokinin-1 Receptor Antagonists; Pain; Substance P | 1999 |
Neurokinin type-1 receptor antagonist inhibits enhancement of T cell functions by substance P in normal and neuromanipulated capsaicin-treated rats.
Topics: Animals; Capsaicin; CD4-Positive T-Lymphocytes; CD5 Antigens; Cell Division; Concanavalin A; Female; Interleukin-2; Lymphocyte Activation; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Specific Pathogen-Free Organisms; Spleen; Substance P | 1999 |
Effects of capsaicin pre-treatment in experimentally-induced secretory otitis media.
Topics: Animals; Capsaicin; Ear, Middle; Epithelium; Male; Otitis Media with Effusion; Rats; Rats, Wistar; Substance P | 1999 |
Bradykinin activates a cross-signaling pathway between sensory and adrenergic nerve endings in the heart: a novel mechanism of ischemic norepinephrine release?
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Nerve Endings; Neurons, Afferent; Norepinephrine; Signal Transduction; Substance P; Synaptosomes | 1999 |
Effect of inflammatory stimuli on the silver staining pattern of the rat carotid endothelium.
Topics: Animals; Capsaicin; Carotid Artery, Common; Cell Adhesion; Endothelium, Vascular; Intercellular Junctions; Leukocytes; Male; Neurogenic Inflammation; Rats; Rats, Wistar; Silver Staining; Substance P | 1999 |
Glial cell line derived neurotrophic factor (GDNF) regulates VR1 and substance P in cultured sensory neurons.
Topics: Animals; Capsaicin; Cells, Cultured; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; In Situ Hybridization; Nerve Growth Factors; Nerve Tissue Proteins; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Drug; Substance P | 1999 |
Thoracic vagus section distal to the recurrent laryngeal nerve reduces substance. P-immunoreactive innervation in the rat bronchial tree.
Topics: Animals; Axons; Bronchi; Capsaicin; Immunoenzyme Techniques; Mediastinum; Rats; Rats, Sprague-Dawley; Recurrent Laryngeal Nerve; Substance P; Vagotomy; Vagus Nerve | 1999 |
Substance P inhibits pancreatic exocrine secretion via a neural mechanism.
Topics: Animals; Atropine; Capsaicin; Male; Nerve Block; Nervous System Physiological Phenomena; Neurons, Afferent; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Tetrodotoxin | 1999 |
Use of NK(1) knockout mice to analyze substance P-induced edema formation.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Edema; Female; Histamine H1 Antagonists; Injections, Intradermal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; p-Methoxy-N-methylphenethylamine; Pyrilamine; Receptors, Neurokinin-1; Skin Diseases; Substance P; Tachykinins | 1999 |
Repeated challenge with dinitrobenzene sulphonic acid in dinitrofluorobenzene-sensitized mice results in vascular hyperpermeability in the trachea: a role for tachykinins.
Topics: Animals; Benzenesulfonates; Capillary Permeability; Capsaicin; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; Indoles; Isoindoles; Male; Mice; Mice, Inbred BALB C; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Substance P; Tachykinins; Trachea | 1999 |
Tachykinins stimulate acid and pepsinogen secretion in the isolated porcine stomach.
Topics: Animals; Capsaicin; Electric Stimulation; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Neurokinin A; Pepsinogen A; Radioimmunoassay; Substance P; Swine; Tachykinins; Vagus Nerve | 1999 |
Acute immobilization stress triggers skin mast cell degranulation via corticotropin releasing hormone, neurotensin, and substance P: A link to neurogenic skin disorders.
Topics: Acute Disease; Animals; Antibodies; Capsaicin; Cell Degranulation; Corticotropin-Releasing Hormone; Male; Mast Cells; Microscopy, Electron; Microtomy; Neurogenic Inflammation; Neuroimmunomodulation; Neuropeptides; Neurotensin; Psoriasis; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Restraint, Physical; Skin; Stress, Physiological; Substance P; Urticaria | 1999 |
Multiphasic morphine modulation of substance P release from capsaicin-sensitive primary afferent fibers.
Topics: Animals; Animals, Newborn; Capsaicin; Male; Morphine; Nerve Fibers; Neurons, Afferent; Potassium; Rats; Rats, Sprague-Dawley; Substance P | 1999 |
Opposite modulation of capsaicin-evoked substance P release by glutamate receptors.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Nociceptors; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei | 1999 |
Inflammatory effect of intratracheal instillation of ultrafine particles in the rabbit: role of C-fiber and mast cells.
Topics: Animals; Capsaicin; Carbachol; Chemotaxis, Leukocyte; Female; Histamine; Histamine Antagonists; Intubation, Intratracheal; Lung; Male; Mast Cells; Microspheres; Nerve Fibers; Neutrophils; p-Methoxy-N-methylphenethylamine; Pneumonia; Polystyrenes; Rabbits; Receptors, Tachykinin; Substance P; Thiorphan | 1999 |
Decreased neuropeptide release may play a role in the pathogenesis of nasal polyps.
Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Capsaicin; Female; Humans; Male; Middle Aged; Nasal Mucosa; Nasal Polyps; Neurokinin A; Neuropeptides; Nose Neoplasms; Prospective Studies; Reference Values; Respiratory Hypersensitivity; Substance P | 1999 |
Effects of nerve stimulation on spontaneously active preparations of the guinea pig ureter.
Topics: Action Potentials; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Electrophysiology; Guinea Pigs; Humans; In Vitro Techniques; Motor Activity; Nervous System Physiological Phenomena; Neurokinin A; Peptides, Cyclic; Substance P; Tachykinins; Thiorphan; Ureter; Urinary Tract Physiological Phenomena | 1999 |
Modulation of sympathetic nerve activity by perivascular sensory nerves in the arterioles of the guinea-pig small intestine.
Topics: Adenosine Triphosphate; Animals; Arterioles; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Membrane Potentials; Neurokinin A; Neurons, Afferent; Substance P; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction | 1999 |
Inhibitory effect of capsaicin on cholinergic transmission in ovine airways: evidence for non-cholinergic contractions.
Topics: Acetylcholine; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Peptides, Cyclic; Quinuclidines; Receptors, Drug; Receptors, Neurokinin-2; Serotonin; Sheep; Substance P; Synaptic Transmission; Trachea | 1999 |
Neuropeptide control of bone marrow neutrophil production is mediated by both direct and indirect effects on CFU-GM.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Hematopoiesis; Hematopoietic Stem Cells; Male; Mice; Neuropeptides; Neutrophils; Norepinephrine; Substance P | 2000 |
Neuropeptides and capsaicin stimulate the release of inflammatory cytokines in a human bronchial epithelial cell line.
Topics: Bronchi; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cell Line, Transformed; Cytokines; Epithelial Cells; Gene Expression; Humans; Interleukin-6; Interleukin-8; Peptide Fragments; Piperidines; Protease Inhibitors; RNA, Messenger; Substance P; Thiorphan; Tumor Necrosis Factor-alpha | 1999 |
Capsaicin-sensitive afferents are involved in signalling transneuronal effects between cutaneous sensory nerves.
Topics: Animals; Capillary Permeability; Capsaicin; Coloring Agents; Denervation; Functional Laterality; Male; Neuritis; Neurons, Afferent; Nociceptors; Peripheral Nerve Injuries; Peripheral Nerves; Plasma; Radioimmunoassay; Rats; Rats, Wistar; Signal Transduction; Skin; Substance P | 2000 |
Effects of capsaicin-induced sensory denervation on osteoclastic resorption in adult rats.
Topics: Animals; Bone Resorption; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Dental Pulp; Immunohistochemistry; Male; Maxilla; Nerve Fibers; Neurons, Afferent; Rats; Rats, Wistar; Substance P | 2000 |
Cholecystokinin-8 enhances nerve growth factor synthesis and promotes recovery of capsaicin-induced sensory deficit.
Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Male; Mice; Nerve Growth Factor; Neurons, Afferent; Pain Threshold; Peripheral Nervous System Diseases; RNA, Messenger; Sincalide; Substance P; Up-Regulation | 2000 |
Enhanced nociception by exogenous and endogenous substance P given into the spinal cord in mice lacking NR(2)A/epsilon(1), an NMDA receptor subunit.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Bradykinin; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Mice; Mice, Knockout; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Pain; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance P | 2000 |
Role of substance P in central control of ovulation in female rats.
Topics: Animals; Capsaicin; Cerebral Ventricles; Enkephalin, Methionine; Epinephrine; Female; Gonadotropin-Releasing Hormone; Homeostasis; Ovulation; Peptide Fragments; Pseudopregnancy; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred BUF; Rats, Wistar; Substance P | 1999 |
Respiratory actions of tachykinins in the nucleus of the solitary tract: effect of neonatal capsaicin pretreatment.
Topics: Animals; Animals, Newborn; Capsaicin; Male; Microinjections; Neurokinin A; Neurokinin B; Peptide Fragments; Rats; Rats, Wistar; Respiratory Mechanics; Solitary Nucleus; Substance P; Tachykinins | 2000 |
Capsaicin-stimulated release of substance P from cultured dorsal root ganglion neurons: involvement of two distinct mechanisms.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Ganglia, Spinal; In Vitro Techniques; Membrane Proteins; Nerve Tissue Proteins; Neurons; Rats; Substance P; Synaptosomal-Associated Protein 25 | 2000 |
Local application of capsaicin into the draining lymph nodes attenuates expression of adjuvant-induced arthritis.
Topics: Afferent Pathways; Animals; Arthritis, Experimental; Capsaicin; Denervation; Freund's Adjuvant; Hindlimb; Injections, Intralymphatic; Lymph Nodes; Male; Nerve Fibers; Rats; Rats, Inbred Lew; Substance P | 2000 |
Evidence for the involvement of ATP, but not of VIP/PACAP or nitric oxide, in the excitatory effect of capsaicin in the small intestine.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Capsaicin; Enzyme Inhibitors; Guinea Pigs; Ileum; In Vitro Techniques; Intestine, Small; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Physalaemin; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyridoxal Phosphate; Receptors, Neurokinin-3; Sincalide; Substance P; Vasoactive Intestinal Peptide | 2000 |
Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors.
Topics: Animals; Capsaicin; Electric Stimulation; Glucagon; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Nerve Fibers; Neurokinin A; Pancreas; Receptors, Neurokinin-1; Somatostatin; Substance P; Swine; Tachykinins; Vagus Nerve | 2000 |
Characterization of nociceptin/orphanin FQ-induced pain responses in conscious mice: neonatal capsaicin treatment and N-methyl-D-aspartate receptor GluRepsilon subunit knockout mice.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Capsaicin; Consciousness; Immunohistochemistry; Injections, Spinal; Male; Mice; Mice, Knockout; Morphine; Nerve Fibers; Nociceptin; Nociceptors; Opioid Peptides; Pain; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Substance P; Time Factors; Vasodilator Agents | 2000 |
Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene.
Topics: Acetic Acid; Animals; Behavior, Animal; Capsaicin; Colon; Cyclophosphamide; Cystitis; Female; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Mustard Plant; Nociceptors; Pain; Physical Stimulation; Plant Extracts; Plant Oils; Receptors, Neurokinin-1; Substance P; Urinary Bladder; Visceral Afferents | 2000 |
Effects of topically applied capsaicin cream on neurogenic inflammation and thermal sensitivity in rats.
Topics: Administration, Topical; Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Pain Threshold; Rats; Rats, Sprague-Dawley; Substance P | 2000 |
Substance P radioimmunoassay for quantitative characterization of sensory neurotransmitter release.
Topics: Alkaloids; Animals; Benzodioxoles; Calibration; Capsaicin; Diterpenes; Electric Stimulation; Enzyme Inhibitors; Female; Neurons, Afferent; Piperidines; Polyunsaturated Alkamides; Radioimmunoassay; Rats; Rats, Wistar; Stimulation, Chemical; Substance P; Trachea | 1999 |
Treatment of gastric ulcers and diarrhea with the Amazonian herbal medicine sangre de grado.
Topics: Animals; Capsaicin; Cyclooxygenase 2; Diarrhea; Diffusion Chambers, Culture; DNA Primers; Dose-Response Relationship, Drug; Electric Stimulation; Gene Expression Regulation, Enzymologic; Guinea Pigs; Ileum; Interleukin-1; Interleukin-6; Intestinal Mucosa; Isoenzymes; Male; Neurons, Afferent; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peru; Phytotherapy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Stomach Ulcer; Substance P; Tumor Necrosis Factor-alpha | 2000 |
Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo.
Topics: Animals; Calcium; Capsaicin; Cell Communication; Electric Stimulation; Guinea Pigs; Inflammation; Male; Membrane Potentials; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Substance P; Trigeminal Ganglion | 2000 |
Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings.
Topics: Afferent Pathways; Animals; Blood Pressure; Capsaicin; Cyclosporine; Disease Models, Animal; Female; Hypertension; Immunohistochemistry; Immunophilins; Kidney; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Endings; Neurons, Afferent; rab3A GTP-Binding Protein; Substance P; Sympathetic Nervous System; Synapsins; Synaptic Vesicles | 2000 |
Distribution of capsaicin-sensitive substance P- and calcitonin gene-related peptide-immunoreactive nerves in bovine respiratory tract.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cattle; Female; Immunohistochemistry; Nerve Fibers; Respiratory Mucosa; Respiratory System; Substance P | 2000 |
Capsaicin induces a slow inward current which is not mediated by substance P in substantia gelatinosa neurons of the rat spinal cord.
Topics: Animals; Capsaicin; Excitatory Postsynaptic Potentials; Nerve Fibers; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Substantia Gelatinosa; Synaptic Transmission | 2000 |
Dihydrocapsaicin treatment depletes peptidergic nerve fibers of substance P and alters mast cell density in the respiratory tract of neonatal sheep.
Topics: Age Factors; Animals; Animals, Newborn; Capsaicin; Coloring Agents; Female; Hydrogen-Ion Concentration; Immunohistochemistry; Lung; Male; Mast Cells; Nasal Septum; Nerve Fibers; Respiratory System; Sheep; Substance P; Time Factors; Tolonium Chloride | 2000 |
Human stem cells express substance P gene and its receptor.
Topics: Capsaicin; Cell Line; Fetal Blood; Gene Expression; Humans; Protein Precursors; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Substance P; Tachykinins | 2000 |
Neonatal capsaicin treatment decreased substance P receptor immunoreactivity in lamina III neurons of the dorsal horn.
Topics: Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Capsaicin; Immunohistochemistry; In Situ Hybridization; Male; Neurokinin-1 Receptor Antagonists; Neurons; Pain Measurement; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Substance P | 2000 |
Substance P in the nucleus of the solitary tract augments bronchopulmonary C fiber reflex output.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Bronchi; Capsaicin; Guinea Pigs; Heart Rate; Hemodynamics; Lung; Male; Microinjections; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Phrenic Nerve; Reflex; Respiratory Mechanics; Solitary Nucleus; Substance P; Trachea | 2000 |
NK-1 receptor desensitization and neutral endopeptidase terminate SP-induced pancreatic plasma extravasation.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Blood Proteins; Capillaries; Capillary Permeability; Capsaicin; Cell Membrane; Evans Blue; Glycopeptides; Infusions, Intravenous; Male; Neprilysin; Neurokinin-1 Receptor Antagonists; Neutrophils; Pancreas; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P | 2000 |
Neural pathways regulating Brunner's gland secretion in guinea pig duodenum in vitro.
Topics: Animals; Brunner Glands; Capsaicin; Carbachol; Choline O-Acetyltransferase; Cholinergic Agonists; Cholinergic Fibers; Dimethylphenylpiperazinium Iodide; Duodenum; Electric Stimulation; Female; Ganglia, Sympathetic; Guanethidine; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Neural Pathways; Neurotransmitter Agents; Nicotinic Agonists; Nicotinic Antagonists; Piperidines; Submucous Plexus; Substance P; Sympatholytics; Tetrodotoxin; Vagotomy; Vagus Nerve | 2000 |
Subclassified acutely dissociated cells of rat DRG: histochemistry and patterns of capsaicin-, proton-, and ATP-activated currents.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cluster Analysis; Ganglia, Spinal; Lectins; Male; Neurons, Afferent; Nociceptors; Pain; Patch-Clamp Techniques; Protons; Rats; Rats, Sprague-Dawley; Substance P | 2000 |
Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Capsaicin; Croton Oil; Dermatitis, Allergic Contact; Dermatitis, Irritant; Enzyme Inhibitors; Female; Glycopeptides; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neprilysin; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Skin; Substance P | 2001 |
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs.
Topics: Administration, Inhalation; Airway Resistance; Animals; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Guinea Pigs; Histamine; Leukocyte Count; Lung; Male; Methacholine Chloride; Neurokinin A; Ovalbumin; Peptide Fragments; Smoking; Substance P; Wakefulness | 2001 |
Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Endocannabinoids; Ganglia, Spinal; In Vitro Techniques; Male; Neurons, Afferent; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Receptors, Cannabinoid; Receptors, Drug; Spinal Cord; Substance P; TRPV Cation Channels | 2001 |
Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor.
Topics: Animals; Capsaicin; Gene Targeting; Inflammation; Male; Mice; Mice, Inbred BALB C; Mutagenesis; Pain; Pain Threshold; Plasma; Receptors, Neuropeptide Y; Substance P | 2001 |
Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation.
Topics: Animals; Benzamides; Capsaicin; Colon; Colonic Diseases, Functional; Electric Stimulation; Male; Mast Cells; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Stress, Physiological; Substance P | 2001 |
Peptide immunoreactivity and ultrastructure of rat urinary bladder nerve fibers after topical desensitization by capsaicin or resiniferatoxin.
Topics: Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Diterpenes; Female; Male; Microscopy, Electron; Neurons, Afferent; Neuropeptide Y; Neuropeptides; Pressure; Rats; Rats, Wistar; Reflex; Substance P; Urinary Bladder; Urination; Vasoactive Intestinal Peptide | 2000 |
Capsaicin pre- and post-treatment on rat monocrotaline pneumotoxicity.
Topics: Animals; Capsaicin; Functional Residual Capacity; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Neprilysin; Neurokinin A; Organ Size; Rats; Rats, Sprague-Dawley; Substance P; Total Lung Capacity | 2000 |
Influence of painful chronic neuropathy on neurogenic inflammation.
Topics: Administration, Topical; Analgesics; Animals; Capsaicin; Chronic Disease; Coloring Agents; Electric Stimulation; Evans Blue; Hot Temperature; Indoles; Isoindoles; Ligation; Male; Nerve Fibers; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sciatic Nerve; Sciatica; Substance P | 2001 |
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Capsaicin; Diclofenac; Duodenum; Gastric Mucins; Male; Misoprostol; Neurokinin A; Oligopeptides; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptor, PAR-2; Receptors, Thrombin; Saliva; Stomach; Substance P | 2001 |
Differential roles of spinal cholera toxin- and pertussis toxin-sensitive G proteins in nociceptive responses caused by formalin, capsaicin, and substance P in mice.
Topics: Animals; Behavior, Animal; Capsaicin; Cholera Toxin; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; GTP-Binding Proteins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Neurons; Nociceptors; Pain; Pain Measurement; Pain Threshold; Pertussis Toxin; Spinal Cord; Substance P; Synaptic Transmission; Virulence Factors, Bordetella | 2001 |
Contribution of C-fibers to leucocyte recruitment in bronchoalveolar lavage fluid and pleural cavity in the rat.
Topics: Animals; Animals, Newborn; Antibodies; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Female; Immunoglobulin E; Immunoglobulin G; Leukocytes; Male; Nerve Fibers; Ovalbumin; Pleura; Pleurisy; Rats; Rats, Wistar; Substance P | 2001 |
Brain-derived neurotrophic factor is released in the dorsal horn by distinctive patterns of afferent fiber stimulation.
Topics: Animals; Brain-Derived Neurotrophic Factor; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Nerve Growth Factor; Neurons, Afferent; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Stimulation, Chemical; Substance P | 2001 |
Airway hyperresponsiveness to bronchoconstrictor challenge after wood smoke exposure in guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Capsaicin; Dinoprost; Guinea Pigs; Histamine; Injections, Intravenous; Lung; Male; Respiratory Mechanics; Smoke; Substance P; Wood | 2001 |
An animal model to assess aversion to intra-oral capsaicin: increased threshold in mice lacking substance p.
Topics: Administration, Oral; Animals; Capsaicin; Drug Tolerance; Irritants; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Neurokinin A; Protein Precursors; Species Specificity; Substance P; Tachykinins; Taste Threshold | 2001 |
Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Capsaicin; Cells, Cultured; Chemokines; Fluorescent Dyes; Ganglia, Spinal; HIV Envelope Protein gp120; Hyperalgesia; Inflammation; Intracellular Fluid; Male; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, CCR4; Receptors, Chemokine; Receptors, CXCR4; RNA, Messenger; Substance P | 2001 |
Tachykinins mediate slow excitatory postsynaptic transmission in guinea pig sphincter of Oddi ganglia.
Topics: Animals; Calcium; Capsaicin; Culture Techniques; Excitatory Postsynaptic Potentials; Female; Ganglia; Guinea Pigs; Male; Membrane Potentials; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Receptors, Tachykinin; Sphincter of Oddi; Substance P; Synaptic Transmission; Tachykinins; Tetrodotoxin | 2001 |
Intrathecally delivered glial cell line-derived neurotrophic factor produces electrically evoked release of somatostatin in the dorsal horn of the spinal cord.
Topics: Animals; Axons; Capsaicin; Drosophila Proteins; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Immunohistochemistry; In Vitro Techniques; Infusions, Parenteral; Kinetics; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurons, Afferent; Neuroprotective Agents; Posterior Horn Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Somatostatin; Substance P | 2001 |
Human colonic anti-secretory activity of the potent NK(1) antagonist, SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease.
Topics: Animals; Antidiarrheals; Capsaicin; Colitis, Ulcerative; Colon; Crohn Disease; Epithelial Cells; Food Hypersensitivity; Guinea Pigs; Humans; Immunoglobulin E; Inflammatory Bowel Diseases; Male; Mast Cells; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Receptors, Neurokinin-1; Species Specificity; Substance P; Tachykinins | 2001 |
Roles of mast cells and sensory nerves in cutaneous vascular hyperpermeability and scratching behavior induced by poly-L-arginine in rats.
Topics: Animals; Behavior, Animal; Capillary Permeability; Capsaicin; Chlorpheniramine; Dose-Response Relationship, Drug; Glycopeptides; Histamine; Histamine H1 Antagonists; Indoles; Injections, Intradermal; Male; Mast Cells; Methysergide; Neurons, Afferent; Peptides; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Skin; Substance P | 2001 |
The capsaicin VR1 receptor mediates substance P release in toxin A-induced enteritis in rats.
Topics: Acute-Phase Reaction; Animals; Bacterial Toxins; Capsaicin; Clostridioides difficile; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Enteritis; Enterotoxins; Ileum; Immunohistochemistry; Intestinal Secretions; Male; Neurogenic Inflammation; Neurons; Peroxidase; Rats; Receptors, Drug; Substance P; Time Factors | 2001 |
The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Proteins; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Female; Injections, Intradermal; Isotonic Solutions; Male; Mast Cells; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Piperidines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Skin; Substance P; Theobromine | 2001 |
Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blepharitis; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Cells, Cultured; Drug Synergism; Female; Ganglia, Spinal; Guinea Pigs; Inflammation; Lectins; Male; Neurokinin A; Neurons; Plant Extracts; Plant Lectins; Rats; Ricinoleic Acids; Seeds; Substance P | 2001 |
Developmental shift of vanilloid receptor 1 (VR1) terminals into deeper regions of the superficial dorsal horn: correlation with a shift from TrkA to Ret expression by dorsal root ganglion neurons.
Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Binding Sites; Capsaicin; Drosophila Proteins; Fluorescent Antibody Technique; Ganglia, Spinal; Hyperalgesia; Lectins; Microscopy, Confocal; Pain Measurement; Pain Threshold; Posterior Horn Cells; Presynaptic Terminals; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Drug; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Skin; Substance P | 2001 |
Neuronal nitric oxide synthase (nNOS) mRNA is down-regulated, and constitutive NOS enzymatic activity decreased, in thoracic dorsal root ganglia and spinal cord of the rat by a substance P N-terminal metabolite.
Topics: Animals; Arginine; Capsaicin; Ganglia, Spinal; Lumbar Vertebrae; Male; Nerve Degeneration; Nerve Fibers; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; Pain; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Substance P; Thoracic Vertebrae | 2001 |
Concurrent release of ATP and substance P within guinea pig trigeminal ganglia in vivo.
Topics: Adenosine Triphosphate; Animals; Cadmium Chloride; Capsaicin; Guinea Pigs; Male; Neurons; Potassium Chloride; Substance P; Trigeminal Ganglion | 2001 |
Capsaicin vanilloid receptor-1 mediates substance P release in experimental pancreatitis.
Topics: Amylases; Animals; Capsaicin; Endocytosis; Male; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis; Peroxidase; Receptors, Drug; Receptors, Neurokinin-1; Severity of Illness Index; Substance P; TRPV Cation Channels | 2001 |
The neurosensory tachykinins substance P and neurokinin A directly induce keratinocyte nerve growth factor.
Topics: Animals; Capsaicin; Cell Line, Transformed; Epidermis; Female; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Nerve Growth Factor; Neurokinin A; Neuropeptides; RNA, Messenger; Substance P; Up-Regulation | 2001 |
Capsaicin in albino rats prevents contralateral testis from the damaging effects posed by ipsilateral testis that underwent torsion.
Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Male; Neurotoxins; Random Allocation; Rats; Spermatic Cord Torsion; Substance P; Testis | 2001 |
Lack of a significant effect of deletion of the tachykinin neurokinin-1 receptor on wound healing in mouse skin.
Topics: Animals; Capsaicin; Edema; Gene Deletion; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Neurokinin-1; Skin; Substance P; Sutures; Wound Healing | 2001 |
Involvement of spinal N-methyl-D-aspartate receptors in capsaicin-induced in vivo release of substance P in the rat dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Nerve Fibers; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance P; Synapses; Synaptic Transmission | 2001 |
Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction.
Topics: Animals; Benzamides; Bradykinin; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Glycopeptides; Guinea Pigs; Indoles; Lung; Male; Metalloendopeptidases; Neurokinin A; Piperidines; Substance P | 2001 |
Local capsaicin application to the stellate ganglion and stellatectomy attenuate neurogenic inflammation in rat bronchi.
Topics: Animals; Axons; Bronchi; Bronchitis; Capillary Permeability; Capsaicin; Female; Ganglionectomy; Immunohistochemistry; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Stellate Ganglion; Substance P; Sympathectomy, Chemical; Vagotomy | 2001 |
CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord.
Topics: Adjuvants, Immunologic; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Mice; Nociceptors; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Receptors, Neurokinin-1; Rimonabant; Spinal Cord; Substance P | 2002 |
Sensory nerves and neuropeptides in uterine cervical ripening.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cervical Ripening; Cervix Uteri; Female; Immunohistochemistry; Labor, Obstetric; Neurons; Neuropeptides; Nitric Oxide Synthase; Plasmids; Postpartum Period; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Complementary; RNA, Messenger; Secretogranin II; Substance P; Transcription, Genetic | 2002 |
Increased synthesis of calcitonin gene-related peptide stimulates keratinocyte proliferation in murine UVB-irradiated skin.
Topics: Animals; Bromodeoxyuridine; Calcitonin Gene-Related Peptide; Capsaicin; Cell Division; Hyperplasia; Keratinocytes; Mice; Mice, Inbred BALB C; Substance P; Ultraviolet Rays | 2002 |
Peripheral activity of a new NK1 receptor antagonist TAK-637 in the gastrointestinal tract.
Topics: Animals; Capsaicin; Digestive System; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Naphthyridines; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Substance P | 2002 |
Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guinea pig airways.
Topics: Adaptation, Physiological; Alveolitis, Extrinsic Allergic; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Lung; Male; Mechanoreceptors; Membrane Potentials; Nerve Fibers; Neurofilament Proteins; Neurons, Afferent; Nodose Ganglion; Substance P | 2002 |
Role of tachykinins in sephadex-induced airway hyperreactivity and inflammation in guinea pigs.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cell Count; Cyclohexylamines; Dextrans; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Indoles; Inflammation; Macrophages; Male; Neurokinin A; Peptides, Cyclic; Receptors, Tachykinin; Substance P; Tachykinins; Time Factors; Vasodilator Agents | 2002 |
Feeble bronchomotor responses in diabetic rats in association with decreased sensory neuropeptide release.
Topics: Animals; Blood Glucose; Body Weight; Bronchial Hyperreactivity; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Guinea Pigs; Insulin; Male; Neural Conduction; Neurons, Afferent; Ovalbumin; Rats; Rats, Wistar; Somatostatin; Substance P; Trachea | 2002 |
Capsaicin-sensitive nerve fibres induce epithelial cell proliferation, inflammatory cell immigration and transforming growth factor-alpha expression in the rat colonic mucosa in vivo.
Topics: Animals; Blotting, Western; Bromodeoxyuridine; Calcitonin Gene-Related Peptide; Capsaicin; Cell Division; Colon; Denervation; Goblet Cells; Immunohistochemistry; Inflammation; Intestinal Mucosa; Male; Nerve Fibers; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Transforming Growth Factor alpha | 2002 |
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Ethanol; Ganglia, Spinal; Hot Temperature; Humans; Male; Neurons, Afferent; Nociceptors; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptors, Drug; Recombinant Proteins; Sensory Thresholds; Substance P; Thermoreceptors; Trigeminal Ganglion; TRPV Cation Channels | 2002 |
Alterations in capsaicin-evoked electrolyte transport during the evolution of guinea pig TNBS ileitis.
Topics: Anesthetics, Local; Animals; Biological Transport; Capsaicin; Carbachol; Cholinergic Agonists; Electric Stimulation; Electrolytes; Epithelial Cells; Guinea Pigs; Ileitis; Ileum; Intestinal Mucosa; Submucous Plexus; Substance P; Tetrodotoxin; Time Factors; Trinitrobenzenesulfonic Acid | 2002 |
Mechanism of the antitussive effect of azelastine in guinea pigs.
Topics: Animals; Antitussive Agents; Bronchoalveolar Lavage Fluid; Capsaicin; Cough; Female; Guinea Pigs; Phthalazines; Substance P; Trachea | 2002 |
Reduced aversion to oral capsaicin following neurotoxic destruction of superficial medullary neurons expressing NK-1 receptors.
Topics: Administration, Oral; Animals; Capsaicin; Cervical Vertebrae; Injections, Intraventricular; Irritants; Male; Medulla Oblongata; Neurons; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Solutions; Spinal Cord; Substance P | 2002 |
Pharmacological profile of (2R-trans)-4-[1-[3,5-bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an orally and centrally active neurokinin-1 receptor antagonist.
Topics: Administration, Oral; Allergens; Animals; Butanols; Capsaicin; Cats; Dogs; Edema; Ferrets; Gerbillinae; Guinea Pigs; Histamine; Kinetics; Malates; Mice; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Platelet Activating Factor; Rabbits; Receptors, Neurokinin-1; Salivation; Substance P; Time Factors | 2002 |
Upregulation of neurokinin-1 receptor expression in rat spinal cord by an N-terminal metabolite of substance P.
Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Ganglia, Spinal; Immunohistochemistry; Inflammation; Isomerism; Male; Pain; Peptide Fragments; Posterior Horn Cells; Presynaptic Terminals; Protein Precursors; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tachykinins; Up-Regulation | 2002 |
Temporomandibular joint nociception: effects of capsaicin on substance P-like immunoreactivity in the rabbit brain stem.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Brain Stem; Capsaicin; Cervical Plexus; Female; Image Processing, Computer-Assisted; Immunohistochemistry; Injections, Intra-Articular; Neural Pathways; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Pain; Rabbits; Statistics as Topic; Substance P; Temporomandibular Joint; Trigeminal Caudal Nucleus; Trigeminal Nuclei; Trigeminal Nucleus, Spinal | 2002 |
Ruthenium red-sensitive cation channels, but not calcitonin gene-related peptide or substance P-mediated mechanisms, protect duodenal villi against acid-induced damage.
Topics: Acids; Animals; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Capsaicin; Cations; Dose-Response Relationship, Drug; Duodenum; Hydrochloric Acid; Hydrogen-Ion Concentration; Intestinal Mucosa; Ion Channels; Male; Neurons, Afferent; Peptide Fragments; Rats; Rats, Sprague-Dawley; Ruthenium Red; Substance P | 2002 |
Spinal neurons that possess the substance P receptor are required for the development of central sensitization.
Topics: Animals; Capsaicin; Cytotoxins; Hyperalgesia; Immunotoxins; Injections, Spinal; Male; N-Glycosyl Hydrolases; Neurons; Nociceptors; Pain Measurement; Physical Stimulation; Plant Proteins; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Stimulation, Chemical; Substance P | 2002 |
Estrogen-dependent regulation of neurokinin 3 receptor-mediated uterine contractility in the rat.
Topics: Acetylcholine; Animals; Capsaicin; Dose-Response Relationship, Drug; Estrogens; Estrus; Female; In Vitro Techniques; Ovariectomy; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Uterine Contraction; Uterus | 2002 |
Vanilloid receptor subtype-1 (VR1) is specifically localized to taste papillae.
Topics: Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Immunohistochemistry; Male; Pain; Rats; Rats, Wistar; Receptors, Drug; Substance P; Taste; Taste Buds; Tongue | 2002 |
Concentration-dependent dual effect of anandamide on sensory neuropeptide release from isolated rat tracheae.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; In Vitro Techniques; Male; Neuropeptides; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Reference Values; Reproducibility of Results; Rimonabant; Sensitivity and Specificity; Somatostatin; Substance P; Trachea | 2003 |
Role of voltage-gated cation channels and axon reflexes in the release of sensory neuropeptides by capsaicin from isolated rat trachea.
Topics: Agatoxins; Anesthetics, Local; Animals; Axons; Cadmium; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Lidocaine; Male; Neuropeptides; omega-Conotoxin GVIA; Rats; Reflex; Sodium Channels; Somatostatin; Spider Venoms; Substance P; Tetrodotoxin; Trachea | 2003 |
Dual sensory innervation of pulmonary neuroepithelial bodies.
Topics: Animals; Animals, Newborn; Calbindin 1; Calbindins; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Epithelial Cells; Female; Lung; Male; Nerve Endings; Neurons, Afferent; Neurosecretory Systems; Nodose Ganglion; Rats; Rats, Wistar; Receptors, Purinergic; S100 Calcium Binding Protein G; Substance P; Vagus Nerve | 2003 |
In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord.
Topics: Animals; Blotting, Western; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hot Temperature; Immunohistochemistry; Injections, Spinal; Male; Mice; Mice, Knockout; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Nociceptin; Opioid Peptides; Pain; Pain Measurement; Pressure; Receptors, Neurokinin-1; Reflex; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Substance P; Synaptic Membranes; Synaptic Transmission | 2003 |
Mechanisms of transforming growth factor-alpha (TGF-alpha) induced gastroprotection against ethanol in the rat: roles of sensory neurons, sensory neuropeptides, and prostaglandins.
Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Ethanol; Gastric Mucosa; Gastritis; Indomethacin; Injections, Intraperitoneal; Male; Neurons, Afferent; Neuropeptides; Probability; Prostaglandins; Radionuclide Imaging; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Stomach; Substance P; Transforming Growth Factor alpha | 2003 |
Bone marrow transplantation reveals an essential synergy between neuronal and hemopoietic cell neurokinin production in pulmonary inflammation.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Capsaicin; Enzyme-Linked Immunosorbent Assay; Gene Deletion; Gene Expression Regulation; Hematopoietic Stem Cells; Immune System; Inflammation; Ligands; Lung; Mice; Mice, Transgenic; Neurokinin A; Neurons; Protein Precursors; Respiration; Substance P; Tachykinins; Time Factors; Trachea | 2003 |
Relationship between capsaicin-evoked substance P release and neurokinin 1 receptor internalization in the rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Microscopy, Confocal; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Time Factors | 2003 |
Nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) regulate substance P release in adult spinal sensory neurons.
Topics: Animals; Bradykinin; Capsaicin; Female; Ganglia, Spinal; Glial Cell Line-Derived Neurotrophic Factor; Membrane Potentials; Nerve Growth Factor; Nerve Growth Factors; Neurons, Afferent; Potassium Chloride; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2003 |
Substance P released from intrinsic airway neurons contributes to ozone-enhanced airway hyperresponsiveness in ferret trachea.
Topics: Animals; Capsaicin; Electric Stimulation; Female; Ferrets; Ganglia; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Neurons; Ozone; Piperidines; Substance P; Trachea | 2003 |
Involvement of primary afferent nerves after abdominal irradiation: consequences on ileal contractile activity and inflammatory mediator release in the rat.
Topics: Animals; Capsaicin; Gastrointestinal Motility; Ileum; Inflammation Mediators; Interleukin-1; Male; Nerve Endings; Neurons, Afferent; Neurotensin; Radiation Injuries, Experimental; Rats; Rats, Wistar; Substance P; Tumor Necrosis Factor-alpha | 2003 |
Acid-induced mesenteric hyperemia in rats: role of CGRP, substance P, prostaglandin, adenosine, and histamine.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Hydrochloric Acid; Hyperemia; Intestinal Mucosa; Laser-Doppler Flowmetry; Male; Mesenteric Artery, Superior; Mesentery; Nerve Tissue Proteins; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Regional Blood Flow; Substance P; Vasodilator Agents | 2003 |
Intrathecal substance p-saporin attenuates operant escape from nociceptive thermal stimuli.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Capsaicin; Conditioning, Operant; Dose-Response Relationship, Drug; Escape Reaction; Female; Hot Temperature; Hyperalgesia; Immunotoxins; Injections, Spinal; Morphine; Pain Measurement; Rats; Rats, Long-Evans; Reaction Time; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Substance P | 2003 |
Effect of intestinal inflammation on capsaicin-sensitive afferents in the ileum of Schistosoma mansoni-infected mice.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Enteric Nervous System; Fluorescent Antibody Technique, Indirect; Ganglia, Spinal; Ileum; Injections, Subcutaneous; Intestinal Mucosa; Male; Mast Cells; Mice; Neurons, Afferent; Nodose Ganglion; Parasitic Diseases, Animal; Receptors, Drug; Schistosomiasis mansoni; Substance P | 2003 |
A role for tachykinins in female mouse and rat reproductive function.
Topics: Animals; Capsaicin; Embryo, Mammalian; Female; Fertility; Gene Expression Regulation; Litter Size; Male; Mice; Neprilysin; Neurokinin A; Neurokinin B; Oocytes; Ovary; Pregnancy; Protein Precursors; Rats; Rats, Wistar; Receptors, Tachykinin; RNA, Messenger; Spermatozoa; Substance P; Tachykinins; Uterus | 2003 |
PAR-2 agonists induce contraction of murine small intestine through neurokinin receptors.
Topics: Animals; Benzamides; Capsaicin; Female; Intestine, Small; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Oligopeptides; Piperidines; Quinuclidines; Receptor, PAR-2; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Tetrodotoxin; Trypsin | 2003 |
Restoration of corneal epithelial barrier function and wound healing by substance P and IGF-1 in rats with capsaicin-induced neurotrophic keratopathy.
Topics: Administration, Topical; Animals; Biological Transport; Capsaicin; Cornea; Corneal Diseases; Disease Models, Animal; Drug Therapy, Combination; Epithelium, Corneal; Female; Fluorescein; Fluorophotometry; Insulin-Like Growth Factor I; Male; Ophthalmic Solutions; Pregnancy; Rats; Rats, Wistar; Substance P; Tears; Trigeminal Nerve Diseases; Wound Healing | 2003 |
Experimental study of the effect of capsaicin on the urinary bladder function in rats.
Topics: Administration, Intravesical; Animals; Capsaicin; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Substance P; Urinary Bladder; Urination | 2000 |
Tachykinin receptor (NK(1), NK(2), NK(3)) binding sites in the rat caudal brainstem following neonatal capsaicin administration.
Topics: Animals; Animals, Newborn; Autoradiography; Brain Stem; Capsaicin; Indicators and Reagents; Iodine Radioisotopes; Neurokinin A; Peptide Fragments; Rats; Receptors, Tachykinin; Substance P; Succinimides | 2003 |
Biologic activity of the tachykinins on lamb and sheep gallbladder.
Topics: Animals; Binding Sites; Capsaicin; Dose-Response Relationship, Drug; Female; Gallbladder; Male; Muscles; Neurokinin A; Neurokinin B; Peptide Fragments; Physalaemin; Protein Structure, Tertiary; Pyrrolidonecarboxylic Acid; Receptors, Tachykinin; Sheep; Substance P; Tachykinins | 2003 |
A study of the cough reflex in idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents; Bradykinin; Brain-Derived Neurotrophic Factor; Bronchial Provocation Tests; Capsaicin; Case-Control Studies; Cough; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocyte Count; Male; Nerve Growth Factor; Neutrophils; Prednisolone; Pulmonary Fibrosis; Sputum; Substance P; Total Lung Capacity; Treatment Outcome | 2003 |
Antinociceptive profiles of crude extract from roots of Angelica gigas NAKAI in various pain models.
Topics: Administration, Oral; Analgesics; Angelica; Animals; Capsaicin; Cytokines; Excitatory Amino Acids; Formaldehyde; Hot Temperature; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Plant Extracts; Plant Roots; Postural Balance; Reaction Time; Substance P | 2003 |
Electrophysiological effects of activating the peptidergic primary afferent innervation of rat mesenteric arteries.
Topics: Animals; Apamin; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Electrophysiology; Endothelium, Vascular; Female; Glyburide; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Neurons, Afferent; Norepinephrine; Peptide Fragments; Potassium Channel Blockers; Rats; Rats, Wistar; Substance P; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Tachykinin substance P signaling involved in diesel exhaust-induced bronchopulmonary neurogenic inflammation in rats.
Topics: Animals; Bronchitis; Capsaicin; Endopeptidases; Female; Immunoenzyme Techniques; Immunohistochemistry; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Neurons, Afferent; Particle Size; Pneumonia; Radiopharmaceuticals; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Substance P; Technetium Tc 99m Aggregated Albumin; Vehicle Emissions | 2003 |
CONTRIBUTION TO THE THEORY THAT SUBSTANCE P HAS A TRANSMITTER ROLE IN SENSITIVE PATHWAY.
Topics: Acetylcholine; Amides; Brain; Capsaicin; Capsicum; Peptides; Physiology; Rats; Research; Spinal Cord; Substance P | 1964 |
Stimulation of spinal 5-HT(2A/2C) receptors potentiates the capsaicin-induced in vivo release of substance P-like immunoreactivity in the rat dorsal horn.
Topics: Animals; Capsaicin; Carrageenan; Inflammation; Male; Microdialysis; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists; Spinal Cord; Substance P | 2003 |
Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin.
Topics: Administration, Inhalation; Adult; Capsaicin; Case-Control Studies; Cetirizine; Chronic Disease; Cough; Disease Susceptibility; Ephedrine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Nasal Decongestants; Nasal Lavage Fluid; Nasal Provocation Tests; Osmolar Concentration; Substance P | 2003 |
Contribution of spinal glutamatergic mechanisms in heterosegmental antinociception induced by noxious stimulation.
Topics: Animals; Benzoates; Capsaicin; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Isoquinolines; Male; Nociceptors; Pyridines; Quinoxalines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Stimulation, Chemical; Substance P | 2003 |
Neurogenic inflammation in mice deficient in heparin-synthesizing enzyme.
Topics: Acute Disease; Amidohydrolases; Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Extracellular Fluid; Female; Heparin; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; p-Methoxy-N-methylphenethylamine; Skin; Substance P; Sulfotransferases | 2004 |
RNA interference prevents lipopolysaccharide-induced preprotachykinin gene expression.
Topics: Animals; Animals, Newborn; Capsaicin; Cells, Cultured; Forced Expiratory Volume; Gene Expression Regulation; Immunoenzyme Techniques; Lipopolysaccharides; Liposomes; Lung Diseases; Nodose Ganglion; Protein Precursors; Rats; Rats, Inbred BN; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Interference; RNA, Messenger; Substance P; Tachykinins | 2003 |
Basal and activity-induced release of substance P from primary afferent fibres in NK1 receptor knockout mice: evidence for negative feedback.
Topics: Afferent Pathways; Animals; Capsaicin; Electric Stimulation; Feedback, Physiological; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Substance P | 2003 |
Capsaicin treatment inhibits osteopenia and heat hyperalgesia induced by chronic constriction injury to the sciatic nerve in rats.
Topics: Animals; Bone Density; Bone Diseases, Metabolic; Capsaicin; Hot Temperature; Hyperalgesia; Male; Nerve Endings; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Substance P | 2003 |
Depletion of substance P and glutamate by capsaicin blocks respiratory rhythm in neonatal rat in vitro.
Topics: Amino Acid Transport System X-AG; Animals; Capsaicin; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Medulla Oblongata; Nerve Fibers; Periodicity; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Respiratory Muscles; Substance P | 2004 |
Effects of neuropeptides on the sumatriptan-disturbed circulation in the optic nerve head of rabbits.
Topics: Animals; Arterioles; Blood-Retinal Barrier; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Male; Microinjections; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neuropeptides; Optic Nerve; Peptide Fragments; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Retinal Vessels; Substance P; Sumatriptan; Vasodilation | 2004 |
Ethanol causes inflammation in the airways by a neurogenic and TRPV1-dependent mechanism.
Topics: Acetaldehyde; Animals; Blood Proteins; Bronchitis; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Ethanol; Guinea Pigs; Male; Receptors, Drug; Substance P | 2004 |
Influence of maturation on constrictive response to stimulation of C-fiber afferents in isolated guinea pig airways.
Topics: Aging; Animals; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Nerve Fibers, Unmyelinated; Neurokinin A; Neurons, Afferent; Osmolar Concentration; Radioimmunoassay; Stimulation, Chemical; Substance P; Trachea; Vasoconstriction | 2004 |
Subtypes of vagal afferent C-fibres in guinea-pig lungs.
Topics: Action Potentials; Adenosine Triphosphate; Afferent Pathways; Animals; Bradykinin; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Electrophysiology; Ganglia; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Laryngeal Nerves; Lung; Male; Nerve Fibers, Unmyelinated; Neurofilament Proteins; Nodose Ganglion; Patch-Clamp Techniques; Physical Stimulation; Substance P; Trachea; Vagus Nerve | 2004 |
Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures.
Topics: Adolescent; Adult; Aged; Animals; Biopsy; Brain; Calcitonin Gene-Related Peptide; Capillaries; Capsaicin; Cell Line; Child; Eccrine Glands; Epidermal Cells; Epidermis; Epithelial Cells; Gene Expression; Hair Follicle; Humans; Mast Cells; Middle Aged; Nerve Fibers; Neurons, Afferent; Nociceptors; Pruritus; Rats; Receptors, Drug; Sebaceous Glands; Spinal Cord; Substance P | 2004 |
Role of capsaicin-sensitive afferent nerves in different models of gastric inflammation in rats.
Topics: Animals; Biomarkers; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Denervation; Disease Models, Animal; Gastric Mucosa; Gastritis; Inflammation Mediators; Male; Malondialdehyde; Neurokinin-1 Receptor Antagonists; Neurotoxins; Peroxidase; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Receptors, Neuropeptide; Sensory Receptor Cells; Substance P; Visceral Afferents | 2004 |
Neonatal capsaicin treatment affects rat thymocyte proliferation and cell death by modulating substance P and neurokinin-1 receptor expression.
Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Atrophy; Autocrine Communication; Binding Sites; Capsaicin; Cell Death; Cell Division; Concanavalin A; Growth Substances; Male; Neuroimmunomodulation; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; RNA, Messenger; Substance P; T-Lymphocytes; Thymus Gland; Up-Regulation | 2004 |
Effects of TAK-637 on NK(1) receptor-mediated mechanisms regulating colonic secretion.
Topics: Animals; Capsaicin; Colforsin; Colon; Electric Stimulation; Electrophysiology; Guinea Pigs; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Male; Naphthyridines; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Receptors, Neurokinin-1; Statistics, Nonparametric; Substance P; Tetrodotoxin | 2004 |
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Enzyme Activators; Enzyme Inhibitors; Humans; Hyperalgesia; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Drug; RNA, Messenger; Spinal Cord; Substance P; Type C Phospholipases | 2004 |
Nerve growth factor treatment enhances release of immunoreactive calcitonin gene-related peptide but not substance P from spinal dorsal horn slices in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; In Vitro Techniques; Male; Mice; Nerve Growth Factors; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2004 |
Greater involvement of neurokinins found in Guinea pig models of severe asthma compared with mild asthma.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Disease Models, Animal; Eosinophils; Guinea Pigs; Lung; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Respiratory Hypersensitivity; Severity of Illness Index; Substance P | 2004 |
Involvement of substance P, CGRP and histamine in the hyperalgesia and cytokine upregulation induced by intraplantar injection of capsaicin in rats.
Topics: Analgesics; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Antagonists; Hyperalgesia; Injections, Spinal; Nerve Growth Factor; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Substance P; Time Factors; Up-Regulation | 2004 |
Pro-nociceptive role of peripheral galanin in inflammatory pain.
Topics: Action Potentials; Animals; Axons; Behavior, Animal; Capsaicin; Cell Count; Dose-Response Relationship, Drug; Drug Interactions; Galanin; Immunohistochemistry; In Vitro Techniques; Inflammation; Male; Microscopy, Electron; Pain; Pain Measurement; Peptide Fragments; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Receptor, Galanin, Type 2; Receptors, Drug; Skin; Substance P | 2004 |
Tachykinin substance P depletion by capsaicin exacerbates inflammatory response to sidestream cigarette smoke in rats.
Topics: Animals; Capsaicin; Cytokines; Female; Lung; Neprilysin; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Smoke; Substance P; Tachykinins | 2004 |
The effect of a chromogranin A-derived peptide (CgA4-16) in the writhing nociceptive response induced by acetic acid in rats.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels, L-Type; Capsaicin; Chromogranin A; Chromogranins; Diltiazem; Dose-Response Relationship, Drug; Indomethacin; Injections, Intraperitoneal; Male; Pain Measurement; Peptide Fragments; Rats; Rats, Wistar; Substance P | 2004 |
Parameters affecting substance P measurement in heart, lung, and skin.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Heart; Hot Temperature; Hydrogen-Ion Concentration; Lung; Mice; Mice, Inbred BALB C; Myocardium; Reproducibility of Results; Sensitivity and Specificity; Skin; Specimen Handling; Substance P; Tissue Extracts | 2004 |
Nerve growth factor-induced substance P in capsaicin-insensitive vagal neurons innervating the lower mouse airway.
Topics: Animals; Capsaicin; Female; Immunohistochemistry; Ion Channels; Mice; Mice, Inbred BALB C; Nerve Growth Factor; Neurons, Afferent; Nodose Ganglion; Receptor, trkA; Respiratory System; Substance P; TRPV Cation Channels | 2004 |
Capsaicin-evoked substance P release in rat dorsal horn increases after peripheral inflammation: a microdialysis study.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Freund's Adjuvant; Male; Microdialysis; Neurogenic Inflammation; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Time Factors; Valine | 2004 |
Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.
Topics: Animals; Brain-Derived Neurotrophic Factor; Capsaicin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hyperalgesia; Male; N-Methylaspartate; Nerve Fibers, Unmyelinated; Organ Culture Techniques; Pain Measurement; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; src-Family Kinases; Stimulation, Chemical; Substance P | 2004 |
Vanilloid receptor VR1-positive primary afferents are glutamatergic and contact spinal neurons that co-express neurokinin receptor NK1 and glutamate receptors.
Topics: Afferent Pathways; Animals; Capsaicin; Fluorescent Antibody Technique; Glutamic Acid; Immunohistochemistry; Male; Membrane Transport Proteins; Microscopy, Electron, Transmission; Nociceptors; Pain; Posterior Horn Cells; Presynaptic Terminals; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Nerve Roots; Substance P; Synaptic Transmission; Vesicular Glutamate Transport Protein 2 | 2004 |
A novel role for tachykinin neurokinin-3 receptors in regulation of human bronchial Ganglia neurons.
Topics: Acetates; Adult; Bronchi; Capsaicin; Electric Stimulation; Evoked Potentials; Female; Ganglia, Parasympathetic; Humans; Male; Microscopy, Confocal; Middle Aged; Nerve Fibers; Neurons, Afferent; Peptide Fragments; Quinolines; Receptors, Neurokinin-3; Substance P; Synaptic Transmission | 2005 |
Combined determination with functional and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid 1 in the myenteric plexus of the rat jejunum.
Topics: Action Potentials; Analysis of Variance; Animals; Autonomic Denervation; Calcitonin Gene-Related Peptide; Capsaicin; Drug Interactions; Immunohistochemistry; In Vitro Techniques; Ion Channels; Jejunum; Male; Muscle Relaxation; Myenteric Plexus; Nerve Fibers; Rats; Rats, Wistar; Substance P; TRPV Cation Channels | 2004 |
The effect of capsaicin on substance P expression in pulp tissue inflammation.
Topics: Animals; Capsaicin; Female; Mandibular Nerve; Pulpitis; Radioimmunoassay; Rats; Rats, Wistar; Statistics, Nonparametric; Substance P | 2005 |
The unit of analysis, and measurement of effect size.
Topics: Animals; Capsaicin; Data Interpretation, Statistical; Mandibular Nerve; Pulpitis; Rats; Rats, Wistar; Research Design; Statistics, Nonparametric; Substance P | 2005 |
Neurokinin a is a main constituent of sensory neurons innervating the anterior segment of the eye.
Topics: Aged; Aged, 80 and over; Animals; Animals, Newborn; Anterior Eye Segment; Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; Female; Fluorescent Antibody Technique, Indirect; Humans; In Situ Hybridization; Male; Middle Aged; Neurokinin A; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Tachykinins; Trigeminal Ganglion | 2005 |
Inhibitory actions of calcitonin gene-related peptide and capsaicin: evidence for local axonal reflexes in the bladder wall.
Topics: Action Potentials; Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Female; Guinea Pigs; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Neurons, Afferent; Nicotinic Agonists; Reflex; Substance P; Urinary Bladder | 2005 |
Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity.
Topics: Absorptiometry, Photon; Animals; Axons; Body Weight; Bone and Bones; Bone Density; Calcitonin Gene-Related Peptide; Capsaicin; Immunoenzyme Techniques; Male; Microscopy, Electron; Muscle, Skeletal; Neurons; Neurotransmitter Agents; Organ Size; Osteoclasts; Osteoporosis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Substance P; Tibia; Time Factors; Tomography, X-Ray Computed | 2005 |
Elimination of rat spinal neurons expressing neurokinin 1 receptors reduces bladder overactivity and spinal c-fos expression induced by bladder irritation.
Topics: Animals; Capsaicin; Cell Nucleus; Cystitis; Female; Fluorescent Antibody Technique; Genes, fos; Immunohistochemistry; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Urinary Bladder; Urinary Bladder, Neurogenic | 2005 |
CB(1) cannabinoid receptor stimulation modulates transient receptor potential vanilloid receptor 1 activities in calcium influx and substance P Release in cultured rat dorsal root ganglion cells.
Topics: Animals; Bradykinin; Calcium; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Capsaicin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dose-Response Relationship, Drug; Dronabinol; Enzyme Induction; Enzyme Inhibitors; Ganglia, Spinal; Isoquinolines; Male; Piperidines; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; RNA, Messenger; Substance P; Sulfonamides; Time Factors | 2005 |
Nociceptive transmitter release in the dorsal spinal cord by capsaicin-sensitive fibers after noxious gastric stimulation.
Topics: Amino Acid Transport System X-AG; Animals; Autonomic Denervation; Calcitonin Gene-Related Peptide; Capsaicin; Female; Ganglia, Spinal; Gastric Mucosa; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Immunohistochemistry; Ion Channels; Neurons, Afferent; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Symporters; Thoracic Vertebrae; TRPV Cation Channels; Visceral Afferents | 2005 |
Role of unmyelinated fibers in electroacupuncture cardiovascular responses.
Topics: Action Potentials; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cell Count; Electroacupuncture; Female; Ganglia, Spinal; Immunohistochemistry; Male; Nerve Fibers, Unmyelinated; Neurons; Rats; Rats, Sprague-Dawley; Stomach; Substance P | 2005 |
Substance P does not play a critical role in neurogenic inflammation in the rat masseter muscle.
Topics: Analgesics; Animals; Capsaicin; Disease Models, Animal; Edema; Inflammation Mediators; Male; Masseter Muscle; Mustard Plant; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Plant Extracts; Plant Oils; Pyrrolidonecarboxylic Acid; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P | 2005 |
Early and late effects of capsaicin pretreatment in otitis media with effusion.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Drug Administration Schedule; Immunohistochemistry; Male; Otitis Media with Effusion; Rats; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide | 2005 |
Mobilisation of specific T cells from lymph nodes in contact sensitivity requires substance P.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Movement; Dermatitis, Contact; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Drug Interactions; Immunohistochemistry; Lymph Nodes; Mice; Nerve Fibers; Quinuclidines; Skin; Substance P; Sympathectomy, Chemical; T-Lymphocytes | 2005 |
Macrophage migration inhibitory factor is released as a complex with alpha1-inhibitor-3 in the intraluminal fluid during bladder inflammation in the rat.
Topics: Acute-Phase Proteins; Animals; Body Fluids; Capsaicin; Cystitis; Macrophage Migration-Inhibitory Factors; Male; Rats; Substance P | 2005 |
Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in the rat.
Topics: Analgesics; Anilides; Animals; Capsaicin; Cells, Cultured; Cinnamates; Dose-Response Relationship, Drug; Drug Interactions; Hypothermia; Ion Channels; Male; Mice; Mice, Inbred BALB C; Neurons, Afferent; Nociceptors; Pain; Peripheral Nervous System; Rats; Rats, Wistar; Sensory Receptor Cells; Substance P; Trigeminal Ganglion; TRPV Cation Channels | 2005 |
Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat.
Topics: Animals; Blood Pressure; Body Temperature; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Ion Channels; Male; Neurons; Neuropeptides; Rats; Rats, Wistar; Somatostatin; Substance P; Sulfonamides; Thiourea; Trachea; TRPV Cation Channels | 2005 |
Involvement of an increased spinal TRPV1 sensitization through its up-regulation in mechanical allodynia of CCI rats.
Topics: Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; In Vitro Techniques; Injections, Spinal; Male; Nerve Tissue Proteins; Neuropeptides; Pain; Pain Measurement; Physical Stimulation; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Substance P; TRPV Cation Channels; Up-Regulation | 2005 |
Functional role of prostacyclin receptor in rat dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Capsaicin; Cells, Cultured; Cyclic AMP; Cystitis, Interstitial; Disease Models, Animal; Female; Ganglia, Spinal; Iloprost; Inflammation Mediators; Membrane Potentials; Neurons, Afferent; Nociceptors; Pain; Potassium Chloride; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Substance P; Vasodilator Agents | 2005 |
Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs.
Topics: Administration, Inhalation; Animals; Bradykinin; Bronchial Spasm; Capsaicin; Citric Acid; Cough; Guinea Pigs; Lung; Male; Mechanoreceptors; Microinjections; Nerve Fibers, Unmyelinated; Neurons, Afferent; Nociceptors; Reflex; Substance P; Tachykinins | 2005 |
TRPV1 activation results in disruption of the blood-brain barrier in the rat.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Capillaries; Capillary Permeability; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Microspheres; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Starch; Substance P; Tetrazoles; Time Factors; TRPV Cation Channels | 2005 |
Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.
Topics: Amides; Animals; Arachidonic Acids; Bronchi; Bronchoconstriction; Calcium Channel Blockers; Camphanes; Cannabinoid Receptor Agonists; Capsaicin; Electric Stimulation; Endocannabinoids; Ethanolamines; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Organ Culture Techniques; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Substance P | 2005 |
Sympathectomy-induced increases in calcitonin gene-related peptide (CGRP)-, substance P- and vasoactive intestinal peptide (VIP)-levels in parotid and submandibular glands of the rat.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Ganglionectomy; Neurotoxins; Organ Size; Parotid Gland; Rats; Rats, Sprague-Dawley; Submandibular Gland; Substance P; Sympathectomy; Urinary Bladder; Vasoactive Intestinal Peptide | 2005 |
Dendritic cells do not transduce inflammatory stimuli via the capsaicin receptor TRPV1.
Topics: Animals; Bone Marrow Cells; Calcium; Capsaicin; Cells, Cultured; Dendritic Cells; Humans; Inflammation; Ion Channels; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Rats; Signal Transduction; Substance P; TRPV Cation Channels | 2005 |
Intrathecally-administered histamine facilitates nociception through tachykinin NK1 and histamine H1 receptors: a study in histidine decarboxylase gene knockout mice.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Behavior, Animal; Capsaicin; Excitatory Amino Acid Antagonists; Female; Formaldehyde; Histamine; Histidine Decarboxylase; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Histamine H1; Receptors, Neurokinin-1; Substance P; Time Factors | 2005 |
Differential inhibitory effects of mu-opioids on substance P- and capsaicin-induced nociceptive behavior in mice.
Topics: Analgesics, Opioid; Animals; Capsaicin; Male; Mice; Narcotics; Pain; Pain Measurement; Receptors, Opioid, mu; Substance P | 2006 |
Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
Topics: Albumins; Analysis of Variance; Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Glycoproteins; Immunohistochemistry; Inflammation; Injections, Intradermal; Iodine Isotopes; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Peroxidase; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Skin; Substance P; Tachykinins; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
Stimulus-evoked release of neuropeptides is enhanced in sensory neurons from mice with a heterozygous mutation of the Nf1 gene.
Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ganglia, Spinal; Heterozygote; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factor; Neuralgia; Neurofibromatosis 1; Neurons, Afferent; Neuropeptides; Organ Culture Techniques; Pain Threshold; Posterior Horn Cells; Presynaptic Terminals; Proto-Oncogene Proteins p21(ras); Substance P; Synaptic Transmission | 2006 |
TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice.
Topics: Animals; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Heart; In Vitro Techniques; Mice; Mice, Knockout; Myocardial Ischemia; Neurokinin-1 Receptor Antagonists; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Recovery of Function; Reperfusion Injury; Substance P; TRPV Cation Channels | 2005 |
Nasal sensory nerve populations responding to histamine and capsaicin.
Topics: Animals; Capsaicin; Cricetinae; Histamine; Histamine H1 Antagonists; Male; Nasal Mucosa; Substance P; Trigeminal Nerve | 2005 |
Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Male; Neurons, Afferent; Pain; Pain Measurement; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin Gene-Related Peptide; Spinal Cord; Spinal Nerves; Substance P; TRPV Cation Channels | 2006 |
Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization.
Topics: Action Potentials; Afferent Pathways; Animals; Biomechanical Phenomena; Bradykinin; Capsaicin; Colon; Colonic Diseases; Denervation; Female; Pelvis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Urinary Bladder | 2006 |
Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Asthma; Blood Pressure; Bradykinin; Capsaicin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Guinea Pigs; Heart Rate; Indomethacin; Lung; Nerve Fibers, Unmyelinated; Prostaglandins; Respiratory Hypersensitivity; Substance P | 2006 |
Postnatal development of substance P-immunoreaction in the trigeminal caudalis of neonatally capsaicin-treated mice.
Topics: Animals; Animals, Newborn; Capsaicin; Immunohistochemistry; Injections, Subcutaneous; Mice; Myelin Basic Protein; Neurons; Substance P; Trigeminal Caudal Nucleus | 2005 |
A new teleocidin analog from Streptomyces sp. MM216-87F4 induces substance P release from rat dorsal root ganglion neurons.
Topics: Animals; Calcium; Capsaicin; Chemical Phenomena; Chemistry, Physical; CHO Cells; Cricetinae; Female; Fermentation; Ganglia, Spinal; Irritants; Isoenzymes; Lyngbya Toxins; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Microscopy, Confocal; Neurons; Plasmids; Protein Kinase C; Rats; Rats, Sprague-Dawley; Streptomyces; Substance P; Tetradecanoylphorbol Acetate | 2006 |
Capsaicin-induced inactivation of sensory neurons promotes a more aggressive gene expression phenotype in breast cancer cells.
Topics: ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Animals; Capsaicin; Caspase 7; Cell Line, Tumor; Denervation; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heart; Heart Neoplasms; Hydrolysis; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neurons, Afferent; Oligonucleotide Array Sequence Analysis; Phenotype; Proto-Oncogene Proteins c-ets; Substance P; Time Factors | 2006 |
12-Acetoxyhawtriwaic acid lactone, a diterpene from Egletes viscosa, attenuates capsaicin-induced ear edema and hindpaw nociception in mice: possible mechanisms.
Topics: Analgesics; Animals; Asteraceae; Capsaicin; Diterpenes; Diterpenes, Clerodane; Ear; Edema; Flowers; Glyburide; Hindlimb; Lactones; Male; Mice; Naloxone; Nociceptors; Substance P; Theophylline; TRPV Cation Channels | 2006 |
Characterization of three different sensory fibers by use of neonatal capsaicin treatment, spinal antagonism and a novel electrical stimulation-induced paw flexion test.
Topics: Animals; Animals, Newborn; Capsaicin; Disease Models, Animal; Electric Stimulation; Foot; Hindlimb; Male; Mice; Nerve Fibers, Unmyelinated; Neurokinin-1 Receptor Antagonists; Neuronal Plasticity; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Pain Threshold; Peripheral Nerve Injuries; Peripheral Nerves; Predictive Value of Tests; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Reflex; Spinal Nerve Roots; Substance P; Synaptic Transmission | 2006 |
Substance P release evoked by capsaicin or potassium from rat cultured dorsal root ganglion neurons is conversely modulated with bradykinin.
Topics: Animals; Boron Compounds; Bradykinin; Capsaicin; Cells, Cultured; Cyclooxygenase 2; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; MAP Kinase Kinase 1; MAP Kinase Signaling System; Neurons; Pain; Potassium; Potassium Chloride; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptor, Bradykinin B2; Signal Transduction; Substance P; Type C Phospholipases | 2006 |
Formalin produces depolarizations in human airway smooth muscle in vitro.
Topics: Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Electrophysiology; Formaldehyde; Humans; In Vitro Techniques; Irritants; Membrane Potentials; Muscle, Smooth; Neuromuscular Depolarizing Agents; Substance P; Trachea | 2006 |
Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV)1 and sensory neuropeptides in the guinea-pig respiratory system.
Topics: Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Epithelium; Gene Expression; Guinea Pigs; Immunohistochemistry; Male; Muscle, Smooth; Respiratory Function Tests; Respiratory System; Substance P; TRPV Cation Channels | 2006 |
Stimulation of sensory neuropeptide release by nociceptin/orphanin FQ leads to hyperaemia in acutely inflamed rat knees.
Topics: Animals; Arthritis, Experimental; Capsaicin; Dose-Response Relationship, Drug; Hyperemia; Image Processing, Computer-Assisted; Joints; Kaolin; Leukocytes; Male; Mast Cells; Neuropeptides; Nociceptin; Opioid Peptides; Rats; Rats, Wistar; Regional Blood Flow; Stimulation, Chemical; Substance P; Synovial Fluid; Vasodilation | 2006 |
Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice.
Topics: Air Pollutants; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Capsaicin; Female; Hydrogen Sulfide; Inflammation Mediators; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Neurokinin-1 Receptor Antagonists; Peroxidase; Pneumonia; Protein Precursors; Substance P; Tachykinins; TRPV Cation Channels | 2006 |
Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Bradykinin; Capsaicin; Chronic Disease; Colitis; Cystitis, Interstitial; Female; Mast Cells; Nerve Endings; Nerve Fibers, Unmyelinated; Neurons, Afferent; Neuropeptides; Pelvis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Urethane; Urinary Bladder | 2007 |
Effect of pituitary adenylate cyclase activating polypeptide-38 on sensory neuropeptide release and neurogenic inflammation in rats and mice.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Ear; Electric Stimulation; Hindlimb; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mustard Plant; Neurogenic Inflammation; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Oils; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin; Substance P | 2006 |
M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: Findings obtained with muscarinic-receptor knockout mouse.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Enteric Nervous System; Ileum; Mice; Mice, Knockout; Muscle, Smooth; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Substance P | 2007 |
Olopatadine attenuates the enhancement of capsaicin-evoked substance P release by bradykinin from cultured dorsal root ganglion neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Capsaicin; Cells, Cultured; Dibenzoxepins; Dose-Response Relationship, Drug; Ganglia, Spinal; Neurons; Olopatadine Hydrochloride; Potassium; Rats; Rats, Wistar; Substance P; Time Factors | 2006 |
Involvement of substance P and neurogenic inflammation in arsenic-induced early vascular dysfunction.
Topics: Analgesics; Animals; Arsenites; Capillary Permeability; Capsaicin; Ear; Endothelium, Vascular; Environmental Pollutants; Histamine; Histamine H1 Antagonists; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Pyrilamine; Receptors, Neurokinin-1; Skin; Sodium Compounds; Substance P; Time Factors | 2007 |
Intradermal injection of capsaicin induces acute substance P release from rat spinal cord dorsal horn.
Topics: Animals; Area Under Curve; Capsaicin; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Injections, Intradermal; Male; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Time Factors | 2006 |
Lowering of interstitial fluid pressure after neurogenic inflammation in mouse skin is partly dependent on mast cells.
Topics: Analgesics, Non-Narcotic; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Extracellular Fluid; Female; Immunohistochemistry; Mast Cells; Mice; Mice, Mutant Strains; Nerve Fibers, Unmyelinated; Neuritis; Pressure; Proto-Oncogene Proteins c-kit; Skin; Substance P | 2007 |
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes.
Topics: Animals; Autoimmunity; Capsaicin; Diabetes Mellitus, Type 1; Female; Inflammation; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Inbred NOD; Neurons, Afferent; Substance P; T-Lymphocytes; TRPV Cation Channels | 2006 |
NK-1 receptors modulate the excitability of ON cells in the rostral ventromedial medulla.
Topics: Animals; Capsaicin; Electrophysiology; Excitatory Amino Acid Agonists; Extracellular Space; Immunohistochemistry; Iontophoresis; Male; Medulla Oblongata; Microscopy, Confocal; N-Methylaspartate; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P | 2007 |
Butyrate sensitizes the release of substance P and calcitonin gene-related peptide evoked by capsaicin from primary cultured rat dorsal root ganglion neurons.
Topics: Animals; Butyrates; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Irritants; Neurons; Neurosecretion; Rats; RNA, Messenger; Substance P; TRPV Cation Channels | 2006 |
Participation of capsaicin-sensitive afferent nerves in the gastric mucosa of patients with Helicobacter pylori-positive or-negative chronic gastritis.
Topics: Adult; Afferent Pathways; Aged; Breath Tests; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Dyspepsia; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Immunohistochemistry; Male; Middle Aged; Substance P; TRPV Cation Channels; Urea; Urease | 2007 |
Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse.
Topics: Animals; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Capsaicin; Endotoxins; Enzyme-Linked Immunosorbent Assay; Female; Histocytochemistry; Inflammation; Interleukin-1beta; Lung; Mice; Mice, Inbred C57BL; Neurons, Afferent; Neuropeptides; Peroxidase; Radioimmunoassay; Somatostatin; Spectrophotometry; Substance P | 2007 |
Neurokinins enhance excitability in capsaicin-responsive DRG neurons.
Topics: Action Potentials; Animals; Capsaicin; Electric Stimulation; Enzyme Activation; Ganglia, Spinal; Intracellular Membranes; Male; Neurokinin A; Neurons, Afferent; Patch-Clamp Techniques; Peptide Fragments; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptors, Neurokinin-2; Signal Transduction; Substance P; Tachykinins | 2007 |
Antinociceptive action of myricitrin: involvement of the K+ and Ca2+ channels.
Topics: Acetic Acid; Analgesics; Animals; Calcium Channels; Calcium Radioisotopes; Calcium Signaling; Capsaicin; Female; Flavonoids; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Injections, Intraventricular; Injections, Spinal; Interleukin-1beta; Ion Channel Gating; Male; Mice; Pain; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Substance P; Tumor Necrosis Factor-alpha | 2007 |
Intraluminal acid induces oesophageal shortening via capsaicin-sensitive neurokinin neurons.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Esophagus; Female; Gastric Acid; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Opossums; Peptide Fragments; Receptors, Neurokinin-2; Substance P; Tissue Culture Techniques | 2007 |
Trophic effects of keratinocytes on the axonal development of sensory neurons in a coculture model.
Topics: Adenosine Triphosphate; Animals; Axons; Brain-Derived Neurotrophic Factor; Calcium; Capsaicin; Cell Line; Coculture Techniques; Culture Media; Ganglia, Spinal; Image Processing, Computer-Assisted; Immunohistochemistry; Keratinocytes; Nerve Growth Factors; Neurons, Afferent; Rats; Rats, Wistar; Substance P | 2007 |
Spinal mechanisms of antinociceptive action caused by diphenyl diselenide.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzene Derivatives; Bradykinin; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Inhibitory Concentration 50; Interleukin-1beta; Male; Mice; Organoselenium Compounds; Pain; Pain Measurement; Spinal Cord; Substance P; Tumor Necrosis Factor-alpha | 2007 |
Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential.
Topics: Animals; Botulinum Toxins; Bradykinin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Exocytosis; Membrane Potentials; Mice; Neurons, Afferent; Nociceptors; Pain; Potassium; Protein Isoforms; R-SNARE Proteins; Rats; SNARE Proteins; Substance P; Synaptic Vesicles; Synaptosomal-Associated Protein 25; Syntaxin 1; Trigeminal Ganglion | 2007 |
Regulatory effect of nerve growth factor on release of substance P in cultured dorsal root ganglion neurons of rat.
Topics: Analgesics, Non-Narcotic; Animals; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Ganglia, Spinal; Gene Expression Regulation; Nerve Growth Factor; Neurons; Radioimmunoassay; Rats; Rats, Wistar; RNA, Messenger; Substance P | 2007 |
A transient unresponsive state of self-scratching behaviour is induced in mice by skin-scratching stimulation.
Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Peptide Fragments; Physical Stimulation; Pruritus; Quinuclidines; Self Stimulation; Signal Transduction; Skin Physiological Phenomena; Substance P | 2007 |
Effects of ralfinamide, a Na+ channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats.
Topics: 4-Aminopyridine; Action Potentials; Animals; Capsaicin; Drug Resistance; Electric Stimulation; Electrophysiology; Fluorobenzenes; Ganglia, Spinal; Male; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Blockers; Substance P; Tetrodotoxin | 2007 |
Effects of sensory denervation by neonatal capsaicin administration on experimental pancreatitis induced by dibutyltin dichloride.
Topics: Acute Disease; Amylases; Animals; Animals, Newborn; Capsaicin; Denervation; Female; Immunohistochemistry; Neurons, Afferent; Organotin Compounds; Pancreas; Pancreatitis; Pancreatitis, Chronic; Pregnancy; Rats; Rats, Inbred Lew; Substance P | 2007 |
Calcitonin gene-related peptide affects synaptic and membrane properties of bronchial parasympathetic neurons.
Topics: Action Potentials; Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Data Interpretation, Statistical; Electric Stimulation; Electrophysiology; Fluorescent Antibody Technique; Ganglia, Parasympathetic; Guinea Pigs; Male; Membranes; Nerve Endings; Parasympathetic Nervous System; Patch-Clamp Techniques; Reflex; Substance P; Synapses | 2008 |
Pelviureteric peristaltic contractions in diabetic rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Humans; In Vitro Techniques; Kidney Pelvis; Male; Matched-Pair Analysis; Muscle Contraction; Muscle Strength; Muscle, Smooth; Neurokinin A; Neurotransmitter Agents; Peristalsis; Rats; Rats, Wistar; Sensory System Agents; Substance P; Ureter | 2007 |
Potentiation of pulmonary reflex response to capsaicin 24h following whole-body acrolein exposure is mediated by TRPV1.
Topics: Acrolein; Air Pollutants; Animals; Capsaicin; Chemoreceptor Cells; Drug Synergism; Irritants; Male; Nerve Fibers, Unmyelinated; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Reflex; Respiration; Respiratory Mechanics; Respiratory System; Sensory System Agents; Substance P; TRPV Cation Channels | 2008 |
Roles of TRPV1 and neuropeptidergic receptors in dorsal root reflex-mediated neurogenic inflammation induced by intradermal injection of capsaicin.
Topics: Analgesics; Animals; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Edema; GABA Antagonists; Injections, Intradermal; Neurogenic Inflammation; Peptide Fragments; Rats; Receptors, Neurokinin-1; Reflex; Spinal Nerve Roots; Substance P; TRPV Cation Channels; Vasodilation | 2007 |
The release of substance P from cultured dorsal root ganglion neurons requires the non-neuronal cells around these neurons.
Topics: Animals; Capsaicin; Cells, Cultured; Ganglia, Spinal; Immunohistochemistry; Potassium Chloride; Rats; Rats, Wistar; Substance P | 2007 |
Targeted disruption of the galanin gene attenuates inflammatory responses in murine skin.
Topics: Animals; Antipruritics; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Galanin; Gene Targeting; Hot Temperature; Humans; Inflammation; Mice; Mice, Knockout; Neurotransmitter Agents; Neutrophils; Skin; Substance P | 2008 |
Transient receptor potential vanilloid type 1 channels act as mechanoreceptors and cause substance P release and sensory activation in rat kidneys.
Topics: Action Potentials; Animals; Blood Pressure; Capsaicin; Cell Membrane; Cytosol; Diterpenes; Electrophysiology; Female; Kidney; Kidney Pelvis; Mechanoreceptors; Models, Biological; Neurokinin-1 Receptor Antagonists; Perfusion; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Sensory System Agents; Substance P; TRPV Cation Channels; Ubiquitin Thiolesterase | 2008 |
The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca2+ is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinase Kinases; Neurons; Phosphatidylinositol 3-Kinases; Radioimmunoassay; Rats; Rats, Wistar; Substance P; TRPV Cation Channels | 2008 |
Paracrine-like excitation of low-threshold mechanoceptive C-fibers innervating rat hairy skin is mediated by substance P via NK-1 receptors.
Topics: Action Potentials; Androstanes; Animals; Benzimidazoles; Capsaicin; Dose-Response Relationship, Radiation; Electric Stimulation; Male; Mechanoreceptors; Nerve Fibers, Unmyelinated; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sensory Thresholds; Skin; Substance P; Time Factors | 2008 |
Impaired responsiveness of renal sensory nerves in streptozotocin-treated rats and obese Zucker diabetic fatty rats: role of angiotensin.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Baroreflex; Capsaicin; Diabetes Mellitus, Experimental; Dinoprostone; Kidney; Losartan; Male; Mechanoreceptors; Neurons, Afferent; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Substance P | 2008 |
Enhancement of cutaneous nerve regeneration by 4-methylcatechol in resiniferatoxin-induced neuropathy.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Catechols; Disease Models, Animal; Diterpenes; Drug Interactions; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Nerve Fibers, Unmyelinated; Nerve Regeneration; Neural Conduction; Neuroprotective Agents; Peripheral Nervous System Diseases; Reaction Time; Skin; Substance P; Ubiquitin Thiolesterase | 2008 |
Formation of neuromuscular junctions and synthesis of sensory neuropeptides in the co-cultures of dorsal root ganglion and cardiac myocytes.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Cell Communication; Cells, Cultured; Coculture Techniques; Ganglia, Spinal; Immunohistochemistry; Microscopy, Electron, Scanning; Myocytes, Cardiac; Neurogenesis; Neuromuscular Junction; Neuropeptides; Nociceptors; Rats; Rats, Wistar; Sensory Receptor Cells; Sensory System Agents; Substance P; Synaptic Transmission | 2008 |
Increased GFR and renal excretory function by activation of TRPV1 in the isolated perfused kidney.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Colorimetry; Dose-Response Relationship, Drug; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Radioimmunoassay; Rats; Rats, Wistar; Sodium; Substance P; TRPV Cation Channels | 2008 |
TRPV1-mediated protection against endotoxin-induced hypotension and mortality in rats.
Topics: Animals; Blood Pressure; Capsaicin; Catecholamines; Endotoxins; Heart Rate; Hypotension; Isoindoles; Lipopolysaccharides; Male; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; TRPV Cation Channels | 2008 |
The effect of neonatal capsaicin treatment on the CGRP-immunoreaction in the trigeminal subnucleus caudalis of mice.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Immunohistochemistry; Mice; Neurons; Substance P; Tissue Distribution; Trigeminal Caudal Nucleus; Trigeminal Ganglion; TRPV Cation Channels | 2008 |
Novel triple neurokinin receptor antagonist CS-003 strongly inhibits neurokinin related responses.
Topics: Animals; Bronchi; Capillary Permeability; Capsaicin; Chlorocebus aethiops; Citric Acid; COS Cells; Cough; Cyclic S-Oxides; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Inositol Phosphates; Male; Molecular Sequence Data; Morpholines; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Trachea | 2008 |
Interdependent regulation of afferent renal nerve activity and renal function: role of transient receptor potential vanilloid type 1, neurokinin 1, and calcitonin gene-related peptide receptors.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Ganglia, Spinal; Isoindoles; Kidney Pelvis; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptide Fragments; Quinuclidines; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Substance P; TRPV Cation Channels | 2008 |
Effects of topical application of tacrolimus on acute itch-associated responses in mice.
Topics: Administration, Topical; Aedes; Animals; Antipruritics; Behavior, Animal; Capsaicin; Female; Histamine; Immunosuppressive Agents; Male; Mice; Mice, Inbred ICR; Pruritus; Serotonin; Substance P; Tacrolimus | 2008 |
Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs.
Topics: Administration, Inhalation; Anesthetics, Local; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cough; Eosinophils; Guinea Pigs; Histamine; Inflammation; Lidocaine; Lung; Male; Ovalbumin; Substance P | 2008 |
Metalloelastase in lungs and alveolar macrophages is modulated by extracellular substance P in mice.
Topics: Animals; Bronchoalveolar Lavage; Capsaicin; Cell Survival; Female; Gene Expression Regulation, Enzymologic; Lung; Macrophages, Alveolar; Matrix Metalloproteinase 12; Mice; Piperidines; Pulmonary Emphysema; Receptors, Neurokinin-1; RNA, Messenger; Smoking; Substance P; Up-Regulation | 2008 |
Substance P stimulates CFTR-dependent fluid secretion by mouse tracheal submucosal glands.
Topics: Animals; Benzoates; Capsaicin; Clotrimazole; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Glands; Irritants; Mice; Mice, Inbred CFTR; Mucus; Neurokinin-1 Receptor Antagonists; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Receptors, Neurokinin-1; Respiratory Mucosa; Substance P; Thiazolidines; Time Factors; Trachea; Tryptophan | 2008 |
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Imidazoles; Mice; Mice, Inbred BALB C; Ovalbumin; Piperidines; Pyrrolidines; Receptors, Histamine H3; Rhinitis, Allergic, Perennial; Substance P; Thiourea | 2008 |
Neurokinin 2 receptor-mediated activation of protein kinase C modulates capsaicin responses in DRG neurons from adult rats.
Topics: Age Factors; Animals; Calcium; Capsaicin; Carcinogens; Cells, Cultured; Ganglia, Spinal; Male; Neurokinin A; Neurokinin B; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Peptide Fragments; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Sensory System Agents; Signal Transduction; Substance P; TRPV Cation Channels | 2008 |
Antinociceptive effect of the Polygala sabulosa hydroalcoholic extract in mice: evidence for the involvement of glutamatergic receptors and cytokine pathways.
Topics: Administration, Oral; Analgesics; Animals; Capsaicin; Cytokines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Interleukin-1beta; Male; Mice; Pain; Pain Measurement; Plant Extracts; Polygala; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P; Tumor Necrosis Factor-alpha | 2008 |
Agonistic behavior of PACAP6-38 on sensory nerve terminals and cytotrophoblast cells.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Line, Tumor; Humans; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Sensory Receptor Cells; Sensory System Agents; Somatostatin; Substance P; Tissue Culture Techniques; Trachea; Trophoblasts | 2008 |
Translocation of GluR1-containing AMPA receptors to a spinal nociceptive synapse during acute noxious stimulation.
Topics: Analysis of Variance; Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Male; Nociceptors; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sensory System Agents; Spinal Cord; Substance P; Synapses; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2008 |
Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.
Topics: Analysis of Variance; Animals; Biphenyl Compounds; Capsaicin; Cells, Cultured; Enzyme Inhibitors; Ganglia, Spinal; Neurons; Peptide Fragments; Phosphorylation; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; Time Factors; TRPV Cation Channels | 2008 |
Involvement of voltage-gated sodium channel Na(v)1.8 in the regulation of the release and synthesis of substance P in adult mouse dorsal root ganglion neurons.
Topics: Animals; Capsaicin; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Ganglia, Spinal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Potassium Chloride; Protein Precursors; Radioimmunoassay; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sciatic Neuropathy; Sodium Channels; Substance P; Tachykinins | 2008 |
Differentiation of neuronal from non-neuronal Substance P.
Topics: Animals; Capsaicin; Cell Differentiation; Male; Mice; Mice, Inbred BALB C; Sensory Receptor Cells; Substance P | 2009 |
The effects of chronic low-dose capsaicin treatment on substance P levels.
Topics: Age Factors; Animals; Capsaicin; Female; Lung; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Skin; Substance P | 2009 |
Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Line, Transformed; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; In Vitro Techniques; Lysophosphatidylcholines; Lysophospholipids; Mice; Multienzyme Complexes; N-Methylaspartate; Phosphodiesterase I; Phospholipases A2; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Signal Transduction; Spinal Cord; Substance P | 2008 |
Salt intake augments hypotensive effects of transient receptor potential vanilloid 4: functional significance and implication.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Ganglia, Spinal; Hypertension; Hypotension; Kidney; Male; Mesenteric Arteries; Phorbol Esters; Rats; Rats, Wistar; Ruthenium Red; Salt Tolerance; Sodium Chloride, Dietary; Substance P; TRPV Cation Channels | 2009 |
Galanin modulates vagally induced contractions in the mouse oesophagus.
Topics: Alkaloids; Animals; Benzodioxoles; Capsaicin; Electric Stimulation; Enzyme Inhibitors; Esophagus; Female; Galanin; Indoles; Male; Mice; Muscle Contraction; NG-Nitroarginine Methyl Ester; Phenanthrolines; Piperidines; Polyunsaturated Alkamides; Receptors, Galanin; Sensory System Agents; Substance P; Vagus Nerve | 2009 |
Exogenous galanin regulates capsaicin-evoked substance P release from primary cultured dorsal root ganglion neurons.
Topics: Analysis of Variance; Animals; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Galanin; Ganglia, Spinal; Irritants; Rats; Rats, Wistar; RNA, Messenger; Sensory Receptor Cells; Statistics, Nonparametric; Substance P; TRPV Cation Channels | 2008 |
Tumor bearing decreases systemic acute inflammation in rats--role of mast cell degranulation.
Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Carrageenan; Cell Degranulation; Dextrans; Edema; Histamine; Inflammation; Mast Cells; Neoplasm Transplantation; Neoplasms; Neutrophil Activation; Neutrophil Infiltration; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Substance P | 2009 |
Interleukin-1alpha regulates substance P expression and release in adult sensory neurons.
Topics: Age Factors; Animals; Capsaicin; Cells, Cultured; Female; Ganglia, Spinal; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Nerve Growth Factor; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Substance P; Up-Regulation | 2009 |
Experimental forearm immobilization in humans reduces capsaicin-induced pain and flare.
Topics: Adolescent; Adult; Area Under Curve; Capsaicin; Female; Forearm; Hand; Humans; Immobilization; Male; Pain; Pain Measurement; Regional Blood Flow; Skin; Skin Physiological Phenomena; Skin Temperature; Substance P; Time Factors; Young Adult | 2009 |
Sex differences in inflammation evoked by noxious chemical, heat and electrical stimulation.
Topics: Analysis of Variance; Animals; Capsaicin; Electric Stimulation; Estrous Cycle; Evans Blue; Female; Foot; Hindlimb; Hot Temperature; Male; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; Sex Characteristics; Skin; Substance P; Time Factors | 2009 |
Role of sensory innervation in the rat pulmonary neutrophil recruitment induced by staphylococcal enterotoxins type A and B.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Degranulation; Enterotoxins; Interleukin-1beta; Lung; Macrophages, Alveolar; Male; Mast Cells; Neuropeptides; Neutrophil Infiltration; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Tachykinin; Serotonin Antagonists; Substance P; Tumor Necrosis Factor-alpha | 2009 |
HCl-activated neural and epithelial vanilloid receptors (TRPV1) in cat esophageal mucosa.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Diterpenes; Electric Stimulation; Epithelial Cells; Esophagus; Hydrochloric Acid; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Stimulation, Chemical; Submucous Plexus; Substance P; Tetrodotoxin; TRPV Cation Channels | 2009 |
Morphine-induced early delays in wound closure: involvement of sensory neuropeptides and modification of neurokinin receptor expression.
Topics: Animals; Capsaicin; Gene Expression Regulation; Male; Morphine; Neurokinin A; Neuropeptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Wound Healing; Wounds and Injuries | 2009 |
Co-administration of nerve growth factor and butyrate regulates vanilloid receptor 1 and substance P levels in cultures of rat dorsal root ganglion neurons.
Topics: Analysis of Variance; Animals; Butyrates; Capsaicin; Cells, Cultured; Drug Synergism; Ganglia, Spinal; Nerve Growth Factor; Neurons; Nociceptors; Rats; Rats, Wistar; RNA, Messenger; Sensory System Agents; Statistics, Nonparametric; Substance P; TRPV Cation Channels | 2009 |
Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon.
Topics: Animals; Atropine; Capsaicin; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Immunohistochemistry; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurokinin A; Pyrazines; Pyridines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Rectum; Substance P; Tetrodotoxin; Time Factors; TRPV Cation Channels; Ubiquitin Thiolesterase | 2009 |
Intrathecal substance P augments morphine-induced antinociception: possible relevance in the production of substance P N-terminal fragments.
Topics: Animals; Antibodies; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Glycopeptides; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Neprilysin; Pain; Pain Measurement; Peptide Fragments; Protease Inhibitors; Spinal Cord; Substance P | 2009 |
Neurokinins inhibit low threshold inactivating K+ currents in capsaicin responsive DRG neurons.
Topics: Alkanesulfonic Acids; Animals; Biophysics; Capsaicin; Cyclohexylamines; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ganglia, Spinal; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sensory System Agents; Substance P; Tachykinins | 2009 |
Proteinase-activated receptor-2 activation evokes oesophageal longitudinal smooth muscle contraction via a capsaicin-sensitive and neurokinin-2 receptor-dependent pathway.
Topics: Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Esophagus; Female; Immunohistochemistry; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Opossums; Peptide Fragments; Receptor, PAR-2; Receptors, Neurokinin-2; Signal Transduction; Substance P; Trypsin | 2010 |
Neurotropin inhibits both capsaicin-induced substance P release and nerve growth factor-induced neurite outgrowth in cultured rat dorsal root ganglion neurones.
Topics: Animals; Capsaicin; Cells, Cultured; Ganglia, Spinal; Nerve Growth Factor; Neurites; Neurons; Polysaccharides; Rats; Substance P | 2010 |
Effects of neurokinin-1 receptor agonism and antagonism in the rostral ventromedial medulla of rats with acute or persistent inflammatory nociception.
Topics: Animals; Capsaicin; Central Nervous System Agents; Freund's Adjuvant; Hot Temperature; Male; Medulla Oblongata; Mustard Plant; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Plant Oils; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Time Factors | 2010 |
Hypotension induced by activation of the transient receptor potential vanilloid 4 channels: role of Ca2+-activated K+ channels and sensory nerves.
Topics: Animals; Animals, Newborn; Apamin; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Charybdotoxin; Drug Combinations; Drug Therapy, Combination; Endothelium, Vascular; Hypotension; Injections, Subcutaneous; Male; Mesenteric Arteries; Nerve Degeneration; Neurons, Afferent; Peptide Fragments; Phorbol Esters; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Sensory System Agents; Substance P; TRPV Cation Channels; Vasodilator Agents | 2010 |
Development of mechanisms associated with neurogenic-mediated skin inflammation during the growth of rats.
Topics: Age Factors; Animals; Capsaicin; Cell Degranulation; Female; Fixatives; Formaldehyde; Male; Mast Cells; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Neurokinin-1; Sensory System Agents; Skin; Substance P | 2010 |
Cannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization.
Topics: Animals; Capsaicin; Electric Stimulation; GABA-B Receptor Antagonists; Injections, Spinal; Male; Morpholines; Neurons; Pain; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Receptors, Neurokinin-1; Receptors, Opioid, mu; Sensory System Agents; Spinal Cord; Spinal Nerve Roots; Substance P; TRPV Cation Channels | 2010 |
Warm SPA-induced hyperthermia confers protection to rats against airway inflammation evoked by capsaicin and substance P.
Topics: Animals; Blotting, Western; Capillary Permeability; Capsaicin; HSP72 Heat-Shock Proteins; Hyperthermia, Induced; Hypotension; Male; Medicine, Traditional; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; Respiratory System; Sensory System Agents; Substance P; Trachea | 2010 |
Effects of acute exposure of alpha 1- and alpha 2-adrenoreceptor agonist or antagonist on capsaicin-evoked substance P release from dorsal root ganglion neurons in vitro.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Capsaicin; Cells, Cultured; Clonidine; Ganglia, Spinal; Neurons; Phenylephrine; Prazosin; Radioimmunoassay; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Yohimbine | 2010 |
Mechanisms of the sensory effects of tacrolimus on the skin.
Topics: Animals; Calcineurin; Calcium Channels; Capsaicin; Immunosuppressive Agents; Male; Models, Animal; Phosphorylation; Sensory Receptor Cells; Skin; Substance P; Swine; Tacrolimus; TRPV Cation Channels | 2010 |
Effects of selective alpha 2-adrenoreceptor stimulation on capsaicin-evoked substance P release from primary cultured dorsal root ganglion neurons.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Capsaicin; Cells, Cultured; Clonidine; Ganglia, Spinal; Neurons; Radioimmunoassay; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; TRPV Cation Channels; Yohimbine | 2010 |
Effects of a high-salt diet on TRPV-1-dependent renal nerve activity in Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Kidney; Kidney Pelvis; Male; Neurons, Afferent; Rats; Rats, Inbred Dahl; Receptors, Neurokinin-1; Sodium Chloride, Dietary; Substance P; TRPV Cation Channels; Urodynamics | 2010 |
IL-1β acutely increases pulmonary SP and permeability without associated changes in airway resistance and ventilation in anesthetized rats.
Topics: Administration, Inhalation; Airway Resistance; Anesthesia; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Evans Blue; Interleukin-1beta; Lung; Male; Nerve Fibers, Unmyelinated; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Substance P | 2011 |
Effects of sangre de drago in an in vitro model of cutaneous neurogenic inflammation.
Topics: Animals; Capsaicin; Cells, Cultured; Coculture Techniques; Croton; Dermatitis; Drug Evaluation, Preclinical; Immunoenzyme Techniques; Keratinocytes; Male; Neurogenic Inflammation; Phytotherapy; Plant Extracts; Sensory Receptor Cells; Sensory System Agents; Substance P; Swine; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2010 |
Sensitized peripheral nociception in experimental diabetes of the rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; In Vitro Techniques; Male; Nerve Fibers; Nociceptors; Pain Measurement; Pain Threshold; Rats; Reaction Time; Sciatic Nerve; Skin; Streptozocin; Substance P | 2010 |
TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation.
Topics: Acetanilides; Acrolein; Animals; Animals, Newborn; Ankyrins; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Formaldehyde; Garlic; Laser-Doppler Flowmetry; Meningeal Arteries; Mustard Plant; Neurons; Peptide Fragments; Plant Oils; Purines; Rats; Sensory System Agents; Substance P; Trigeminal Ganglion; TRPA1 Cation Channel; TRPC Cation Channels; Vasodilation | 2011 |
Properties of substance P-stimulated mucus secretion from porcine tracheal submucosal glands.
Topics: Animals; Anions; Calcium; Capsaicin; Carbachol; Cystic Fibrosis Transmembrane Conductance Regulator; Fura-2; Humans; In Vitro Techniques; Microscopy, Interference; Mucus; Respiratory Mucosa; Substance P; Sus scrofa; Time Factors; Trachea; Type C Phospholipases | 2011 |
Activation of CaMKII and ERK1/2 contributes to the time-dependent potentiation of Ca2+ response elicited by repeated application of capsaicin in rat DRG neurons.
Topics: Animals; Benzylamines; Butadienes; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ganglia, Spinal; Male; Membrane Potentials; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuronal Plasticity; Neurons; Nitriles; Patch-Clamp Techniques; Protein Kinase C; Protein Kinase Inhibitors; Pyrethrins; Rats; Rats, Sprague-Dawley; Recovery of Function; Sensory System Agents; Substance P; Sulfonamides; Tachyphylaxis; Time Factors; TRPV Cation Channels | 2011 |
Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones.
Topics: Animals; Autocrine Communication; Capsaicin; Cells, Cultured; Ganglia, Spinal; Gene Expression Regulation; Lipopolysaccharides; Mice; Mice, Transgenic; Receptors, Neurokinin-1; Sensory Receptor Cells; Sensory System Agents; Substance P; Transgenes; TRPV Cation Channels | 2011 |
TRPV1, NK1 receptor and substance P immunoreactivity and gene expression in the rat lumbosacral spinal cord and urinary bladder after systemic, low dose vanilloid administration.
Topics: Animals; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Lumbar Vertebrae; Male; Rats; Rats, Wistar; Receptors, Neurokinin-1; RNA, Messenger; Sacrum; Spinal Cord; Substance P; TRPV Cation Channels; Urinary Bladder | 2011 |
Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux.
Topics: Adult; Aged; Asthma; Capsaicin; Chronic Disease; Cough; Cross-Sectional Studies; Female; Gastroesophageal Reflux; Histamine; Humans; Male; Middle Aged; Prospective Studies; Prostaglandin D2; Reflex; Respiratory Function Tests; Sputum; Substance P; Tryptases | 2011 |
Degeneration of capsaicin sensitive sensory nerves enhances myocardial injury in acute myocardial infarction in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Caspase 3; Myocardial Infarction; Myocardium; Nerve Degeneration; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Rats; Substance P | 2012 |
Cardioprotection by ischemic postconditioning is lost in isolated perfused heart from diabetic rats: Involvement of transient receptor potential vanilloid 1, calcitonin gene-related peptide and substance P.
Topics: Animals; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Diabetes Mellitus, Experimental; Heart; In Vitro Techniques; Ischemic Postconditioning; Male; Myocardial Reperfusion Injury; Myocardium; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rats; Rats, Sprague-Dawley; Substance P; TRPV Cation Channels; Ventricular Function | 2011 |
Inhibition of ERK phosphorylation by substance P N-terminal fragment decreases capsaicin-induced nociceptive response.
Topics: Animals; Behavior, Animal; Capsaicin; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Injections, Spinal; Male; MAP Kinase Signaling System; Mice; Pain; Pain Measurement; Peptide Fragments; Phosphorylation; Protein Kinase Inhibitors; Substance P | 2011 |
Chili anyone?
Topics: Analgesics; Capsaicin; Capsicum; Food-Drug Interactions; Humans; Pain; Substance P | 2011 |
Persistent epithelial barrier alterations in a rat model of postinfectious gut dysfunction.
Topics: Animals; Capsaicin; Chymases; Enteric Nervous System; Gastrointestinal Tract; Inflammation; Intestinal Mucosa; Ion Transport; Male; Mast Cells; Mastocytosis; Neurotransmitter Agents; Permeability; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Blockers; Substance P; Tetrodotoxin; Trichinella spiralis; Trichinellosis | 2011 |
Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli.
Topics: Animals; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Knockout; Neurons; Neurons, Afferent; Oligopeptides; Pain; Pain Measurement; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Tachykinins | 2011 |
Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling.
Topics: Animals; Capsaicin; Cell Nucleus; Chemokines; Cytokines; Extracellular Signal-Regulated MAP Kinases; Hydrogen Sulfide; Inflammation; Male; Mice; NF-kappa B; Phosphorylation; Sepsis; Substance P; TRPV Cation Channels | 2011 |
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia.
Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Disease Models, Animal; Formaldehyde; Glycyrrhetinic Acid; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ligation; Male; Neuralgia; Neurokinin A; Neurokinin B; Pain; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Sciatic Nerve; Substance P | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones | 2012 |
Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats.
Topics: Analgesics, Non-Narcotic; Animals; Bradykinin; Capsaicin; Carrageenan; Chalcone; Cyclooxygenase 2; Drugs, Chinese Herbal; Ganglia, Spinal; Inflammation; Male; Pain; Plant Extracts; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve; Substance P; Tachykinins | 2012 |
Tonic postganglionic sympathetic inhibition induced by afferent renal nerves?
Topics: Animals; Blood Pressure; Capsaicin; Heart Rate; Isoindoles; Kidney; Male; Models, Animal; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Sympathetic Fibers, Postganglionic; TRPV Cation Channels | 2012 |
TRESK gene recombinant adenovirus vector inhibits capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.
Topics: Adenoviridae; Animals; Antipruritics; Capsaicin; Cells, Cultured; Ganglia, Spinal; Genetic Vectors; Neurons; Potassium Channels; Rats; Rats, Sprague-Dawley; Substance P | 2012 |
Complex regulation of capsaicin on intracellular second messengers by calcium dependent and independent mechanisms in primary sensory neurons.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Cyclic AMP; Cyclic GMP; Male; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Signal Transduction; Substance P; TRPV Cation Channels | 2012 |
Oxygen radicals and substance P in perinatal hypoxia-exaggerated, monocrotaline-induced pulmonary hypertension.
Topics: Animals; Antioxidants; Atmosphere Exposure Chambers; Blood Pressure; Body Weight; Capsaicin; Female; Heart Rate; Humans; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reactive Oxygen Species; Sensory System Agents; Substance P | 2012 |
Inhibitory effect of botulinum toxin type A on the NANC system in rat respiratory models of neurogenic inflammation.
Topics: Animals; Arterial Occlusive Diseases; Botulinum Toxins, Type A; Brain Stem; Capsaicin; Disease Models, Animal; Lung; Male; Neurogenic Inflammation; Neurotransmitter Agents; Pneumonia; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Substance P; Synaptosomal-Associated Protein 25 | 2012 |
Activation of vagus nerve by semapimod alters substance P levels and decreases breast cancer metastasis.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Female; Hydrazones; Liver Neoplasms, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neprilysin; Sensory Receptor Cells; Substance P; Vagotomy; Vagus Nerve | 2012 |
De novo expression of neurokinin-1 receptors by spinoparabrachial lamina I pyramidal neurons following a peripheral nerve lesion.
Topics: Animals; Brachial Plexus; Brain Stem; Capsaicin; Cholera Toxin; Disease Models, Animal; Gene Expression Regulation; Hyperalgesia; Male; Microscopy, Confocal; Neural Pathways; Peripheral Nerve Injuries; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P | 2013 |
Cellular mechanism underlying formaldehyde-stimulated Cl- secretion in rat airway epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Biological Transport; Capsaicin; Cells, Cultured; Chlorides; Colforsin; Epinephrine; Epithelial Cells; Formaldehyde; Imines; Male; Nerve Endings; ortho-Aminobenzoates; Quinuclidines; Rats; Respiratory Mucosa; Substance P; Trachea; TRPV Cation Channels | 2013 |
Neuropeptides activate TRPV1 in rheumatoid arthritis fibroblast-like synoviocytes and foster IL-6 and IL-8 production.
Topics: Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Capsaicin; Case-Control Studies; Humans; Interleukin-6; Interleukin-8; Substance P; Synovial Membrane; TRPV Cation Channels | 2013 |
Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice.
Topics: Acetanilides; Animals; Asthma; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Formaldehyde; Immunoglobulin E; Immunohistochemistry; Interleukin-1beta; Interleukin-4; Interleukin-6; Lung; Male; Mice; Mice, Inbred BALB C; Neuropeptides; Ovalbumin; Purines; Substance P; Transient Receptor Potential Channels | 2013 |
Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum.
Topics: Animals; Capsaicin; Gastrointestinal Transit; Intestines; Isothiocyanates; Macrophages; Male; Mast Cells; Nociception; Peritoneum; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels | 2013 |
Restoration of endogenous substance P is associated with inhibition of apoptosis of retinal cells in diabetic rats.
Topics: Animals; Apoptosis; Capsaicin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gene Expression; Male; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Substance P | 2013 |
Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure.
Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Female; Flavanones; Guinea Pigs; Lung; Male; Neprilysin; Neurogenic Inflammation; Nicotiana; Propylene Glycols; Receptors, Neurokinin-1; Smoke; Substance P; Thiazolidines | 2013 |
[The role of NMDA and NK1 receptors in cardiac nociceptive information transmissions in the spinal cords of rats].
Topics: Animals; Biphenyl Compounds; Capsaicin; Chest Pain; Dizocilpine Maleate; Heart; Male; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P; Synaptic Transmission | 2013 |
Trigeminal nerve stimulation triggers oral mast cell activation and vascular permeability.
Topics: Animals; Antipruritics; Capillary Permeability; Capsaicin; Evans Blue; Inflammation; Male; Mast Cells; Mouth; Rats; Rats, Sprague-Dawley; Substance P; Transcutaneous Electric Nerve Stimulation; Trigeminal Nerve | 2014 |
Botulinum toxin B in the sensory afferent: transmitter release, spinal activation, and pain behavior.
Topics: Afferent Pathways; Animals; Anti-Dyskinesia Agents; Botulinum Toxins; Botulinum Toxins, Type A; Capsaicin; Functional Laterality; Gene Expression Regulation; Hindlimb Suspension; Male; Mice; Mice, Inbred C57BL; Muscle Strength; Nociceptors; Pain; Pain Threshold; Posterior Horn Cells; Receptors, Neurokinin-1; Spinal Cord; Substance P; Time Factors | 2014 |
Involvement of multiple µ-opioid receptor subtypes on the presynaptic or postsynaptic inhibition of spinal pain transmission.
Topics: Analgesics; Animals; Capsaicin; Male; Mice; N-Methylaspartate; Nociception; Oligopeptides; Pain; Presynaptic Terminals; Receptors, Opioid, mu; Somatostatin; Substance P; Synaptic Transmission | 2014 |
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Acids; Formaldehyde; Glutamic Acid; Hyperalgesia; Ischemia; Ketanserin; Male; Mice; Monoterpenes; Neuralgia; Pain, Postoperative; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Stomach Ulcer; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Distinct subclassification of DRG neurons innervating the distal colon and glans penis/distal urethra based on the electrophysiological current signature.
Topics: Acetylcholine; Action Potentials; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colon; Ganglia, Spinal; Glycoproteins; Intermediate Filaments; Lectins; Male; Neurons, Afferent; Penis; Rats; Rats, Sprague-Dawley; Substance P; TRPV Cation Channels; Urethra; Versicans | 2014 |
Acid mediates a prolonged antinociception via substance P signaling in acid-induced chronic widespread pain.
Topics: Acid Sensing Ion Channels; Acids; Animals; Capsaicin; Chronic Pain; Cnidarian Venoms; Disease Models, Animal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Pain Measurement; Signal Transduction; Substance P; TRPV Cation Channels | 2014 |
Characteristics of dorsal root ganglia neurons sensitive to Substance P.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Capsaicin; Ganglia, Spinal; Hydrogen-Ion Concentration; Male; Neurons; Normal Distribution; Rats; Rats, Wistar; Receptors, Purinergic P2X3; Substance P; TRPV Cation Channels | 2014 |
Prenatal nicotinic exposure augments cardiorespiratory responses to activation of bronchopulmonary C-fibers.
Topics: Animals; Apnea; Brain-Derived Neurotrophic Factor; Bronchoalveolar Lavage Fluid; Capsaicin; Diaphragm; Electromyography; Female; Ganglia; Humans; Hypoxia; Infant, Newborn; Male; Methacholine Chloride; Nerve Fibers, Unmyelinated; Nerve Growth Factor; Nicotine; Nodose Ganglion; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, trkA; Receptor, trkB; Recombinant Proteins; Sensory System Agents; Smoking; Substance P; Sudden Infant Death; TRPV Cation Channels | 2015 |
Sensory nerves contribute to cutaneous vasodilator response to cathodal stimulation in healthy rats.
Topics: Acid Sensing Ion Channels; Amiloride; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electrodes; Electrophysiology; Hydrogen-Ion Concentration; Laser-Doppler Flowmetry; Male; Microcirculation; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Sensory Receptor Cells; Skin; Substance P; TRPV Cation Channels; Vasodilation; Vasodilator Agents | 2015 |
Prenatal nicotinic exposure upregulates pulmonary C-fiber NK1R expression to prolong pulmonary C-fiber-mediated apneic response.
Topics: Adenosine; Animals; Animals, Newborn; Apnea; Bronchoalveolar Lavage Fluid; Capsaicin; Female; Ganglia; Lung; Male; Nerve Fibers, Unmyelinated; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; RNA, Messenger; Substance P; TRPV Cation Channels; Up-Regulation; Vagus Nerve | 2016 |
5-HT7 Receptors Are Not Involved in Neuropeptide Release in Primary Cultured Rat Trigeminal Ganglion Neurons.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P; Trigeminal Ganglion | 2016 |
Effect of transient receptor potential vanilloid-1 on cough hypersensitivity induced by particulate matter 2.5.
Topics: Animals; Capillary Permeability; Capsaicin; Central Nervous System Diseases; Cough; Guinea Pigs; Herpesvirus 1, Suid; Hypersensitivity; Male; Particulate Matter; Respiratory Hypersensitivity; Signal Transduction; Substance P; TRPV Cation Channels; Vagus Nerve | 2016 |
Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Cancer Pain; Capsaicin; Cell Line, Tumor; Coculture Techniques; Ganglia, Spinal; Hedgehog Proteins; Humans; Mice; Mice, Nude; Nerve Growth Factor; Nerve Growth Factors; Pancreas; Pancreatic Neoplasms; Pancreatic Stellate Cells; Patch-Clamp Techniques; Signal Transduction; Substance P; TRPV Cation Channels | 2016 |
Biglycan Inhibits Capsaicin-Induced Substance P Release by Cultured Dorsal Root Ganglion Neurons.
Topics: Animals; Astrocytes; Biglycan; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Neurons; Rabbits; Sensory System Agents; Substance P | 2016 |
Development of a spontaneously active dorsal root ganglia assay using multiwell multielectrode arrays.
Topics: Action Potentials; Animals; Bradykinin; Calcium Channel Blockers; Capsaicin; Cells, Cultured; Embryo, Mammalian; Female; Ganglia, Spinal; Hot Temperature; Membrane Transport Modulators; Mibefradil; Neurons; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Channel Blockers; Sodium Chloride; Substance P; Tetrodotoxin | 2016 |
The Bisphosphonates Clodronate and Etidronate Exert Analgesic Effects by Acting on Glutamate- and/or ATP-Related Pain Transmission Pathways.
Topics: Acetic Acid; Adenosine Triphosphate; Analgesics; Animals; Bone Density Conservation Agents; Capsaicin; Clodronic Acid; Etidronic Acid; Excitatory Amino Acid Agonists; Foscarnet; Glutamic Acid; Lumbar Vertebrae; Mice; Mice, Inbred BALB C; N-Methylaspartate; Pain; Sodium-Phosphate Cotransporter Proteins; Spinal Cord; Substance P | 2016 |
Role of capsaicin-sensitive nerves and tachykinins in mast cell tryptase-induced inflammation of murine knees.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Edema; Hyperalgesia; Knee Joint; Male; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Pain; Protein Precursors; Receptor, PAR-2; Receptors, Neurokinin-1; Substance P; Tachykinins; Touch; TRPV Cation Channels; Tryptases | 2016 |
Capsaicin-Sensitive Sensory Nerves Mediate the Cellular and Microvascular Effects of H2S via TRPA1 Receptor Activation and Neuropeptide Release.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Line; Cells, Cultured; Dipeptides; Diterpenes; Female; Glyburide; Hydrogen Sulfide; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Potassium Chloride; Quinazolines; Receptors, Neurokinin-1; Sensory Receptor Cells; Substance P; Transient Receptor Potential Channels; Trigeminal Ganglion; TRPA1 Cation Channel; Vasodilation | 2016 |
Substance P activates Mas-related G protein-coupled receptors to induce itch.
Topics: Adolescent; Adult; Aged; Animals; Capsaicin; Cells, Cultured; Female; Ganglia, Spinal; Humans; Male; Mice, Transgenic; Middle Aged; Pruritus; Receptors, G-Protein-Coupled; Receptors, Neurokinin-1; Sensory Receptor Cells; Substance P; Young Adult | 2017 |
A Comprehensive Method To Quantify Adaptations by Male and Female Mice With Hot Flashes Induced by the Neurokinin B Receptor Agonist Senktide.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Body Temperature; Capsaicin; Disease Models, Animal; Female; Hot Flashes; Hot Temperature; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Preoptic Area; Proto-Oncogene Proteins c-fos; Receptors, Neurokinin-3; Skin Temperature; Substance P | 2017 |
Opioid receptor activation is involved in neuroprotection induced by TRPV1 channel activation against excitotoxicity in the rat retina.
Topics: Animals; beta-Endorphin; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Male; Naloxone; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Retina; Signal Transduction; Substance P; TRPV Cation Channels | 2017 |
Capsaicin-induced rapid neutrophil leukocyte activation in the rat urinary bladder microcirculatory bed.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Male; Microcirculation; Neurons, Afferent; Neutrophils; Rats; Rats, Sprague-Dawley; Substance P; Urinary Bladder | 2018 |
The research of the possible mechanism and the treatment for capsaicin-induced cough.
Topics: Animals; Antitussive Agents; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Codeine; Cough; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Guinea Pigs; Male; Neurokinin A; Pyrrolidines; Substance P; TRPV Cation Channels; Urea | 2018 |
Transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 contribute to the progression of colonic inflammation in dextran sulfate sodium-induced colitis in mice: Links to calcitonin gene-related peptide and substance P.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Dextran Sulfate; Disease Models, Animal; Disease Progression; Male; Mice, Inbred C57BL; Nerve Fibers; Pain; Substance P; TRPA1 Cation Channel; TRPV Cation Channels; Up-Regulation | 2018 |
Potentiation of capsaicin-induced neurogenic inflammation by 5-HT7 receptors in the rat hind paw: Involvement of calcitonin gen-related peptide.
Topics: Animals; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Foot; Humans; Male; Neurogenic Inflammation; Neurons, Afferent; Phenols; Rats; Receptors, Calcitonin Gene-Related Peptide; Receptors, Serotonin; Substance P; Sulfonamides | 2018 |
Activation of orexin-1 receptors in the ventrolateral periaqueductal grey matter (vlPAG) modulates pulpal nociception and the induction of substance P in vlPAG and trigeminal nucleus caudalis.
Topics: Animals; Benzoxazoles; Bicuculline; Capsaicin; Dental Pulp; Fluorescent Antibody Technique; Male; Naphthyridines; Nociception; Orexins; Periaqueductal Gray; Rats; Rats, Wistar; Substance P; Trigeminal Nuclei; Urea | 2019 |
Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn.
Topics: Action Potentials; Analgesics; Animals; Capsaicin; Cholera Toxin; Extracellular Signal-Regulated MAP Kinases; Gastrin-Releasing Peptide; In Vitro Techniques; Interneurons; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurotransmitter Agents; Patch-Clamp Techniques; Physical Stimulation; Protein Precursors; RNA, Messenger; Sensory System Agents; Spinal Cord Dorsal Horn; Statistics, Nonparametric; Substance P; Tachykinins; Transduction, Genetic | 2019 |
Involvement of Substance P in the Analgesic Effect of Low-Level Laser Therapy in a Mouse Model of Chronic Widespread Muscle Pain.
Topics: Acids; Animals; Capsaicin; Chronic Pain; Cnidarian Venoms; Disease Models, Animal; Dose-Response Relationship, Drug; Fibromyalgia; Laser Therapy; Low-Level Light Therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Musculoskeletal Pain; Protein Precursors; Signal Transduction; Substance P; Tachykinins; TRPV Cation Channels | 2019 |
Calcium imaging of primary canine sensory neurons: Small-diameter neurons responsive to pruritogens and algogens.
Topics: Animals; Cadaver; Calcium Radioisotopes; Capsaicin; Cattle; Cells, Cultured; Chloroquine; Dogs; Ganglia, Spinal; Histamine; Humans; Laminectomy; Molecular Imaging; Neurotransmitter Agents; Pain; Peptide Fragments; Pruritus; Radiopharmaceuticals; Sensory Receptor Cells; Serotonin; Serotonin Receptor Agonists; Substance P | 2019 |
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.
Topics: Administration, Inhalation; Age Factors; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Neurokinin A; Neurokinin B; Rats; Rats, Sprague-Dawley; Respiration; Sevoflurane; Substance P; Trachea; TRPV Cation Channels | 2020 |
Effect of Capsaicinoids on Neurophysiological, Biochemical, and Mechanical Parameters of Swallowing Function.
Topics: Adult; Biomechanical Phenomena; Capsaicin; Cerebral Cortex; Deglutition; Electromyography; Esophageal Sphincter, Upper; Female; Healthy Volunteers; Humans; Magnetoencephalography; Male; Manometry; Pharynx; Random Allocation; Saliva; Sensory System Agents; Substance P; Young Adult | 2021 |
Tachykinins amplify the action of capsaicin on central histaminergic neurons.
Topics: Animals; Capsaicin; Histamine; Mice; Neurons; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Tachykinins | 2022 |
Pentobarbital may protect against neurogenic inflammation after surgery via inhibition of substance P release from peripheral nerves of rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Calcium Channels; Capsaicin; Cells, Cultured; Ganglia, Spinal; Ketamine; Male; Neurogenic Inflammation; Pentobarbital; Peripheral Nerves; Rats; Rats, Wistar; Sensory System Agents; Substance P; TRPV Cation Channels | 2022 |
Functional validation of co-culture model of human keratinocytes and neuronal cell line for sensitive skin by using transient receptor potential channel vanilloid subfamily member 1 antagonist.
Topics: Animals; Capsaicin; Cell Line; Coculture Techniques; Cytokines; Humans; Keratinocytes; Neuroblastoma; Neuropeptides; Substance P; TRPV Cation Channels | 2023 |
New human in vitro co-culture model of keratinocytes and sensory neurons like cells releasing substance P with an evaluation of the expression of ZIKV entry receptors: A potent opportunity to test Zika virus entry and to study Zika virus' infection in neu
Topics: Animals; Capsaicin; Coculture Techniques; Humans; Keratinocytes; Sensory Receptor Cells; Substance P; Virus Internalization; Zika Virus; Zika Virus Infection | 2023 |