Compounds > capsaicin

capsaicin and simvastatin

capsaicin has been researched along with simvastatin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, JG; Liu, JM; Lu, YN; Shi, F; Zhai, XJ1
Chen, F; Lu, Y; Wang, N; Zhai, X; Zhang, X; Zhu, C1

Other Studies

5 other study(ies) available for capsaicin and simvastatin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Food-drug interactions: effect of capsaicin on the pharmacokinetics of simvastatin and its active metabolite in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Administration, Oral; Animals; Anticholesteremic Agents; Area Under Curve; Biological Availability; Capsaicin; Capsicum; Chromatography, Liquid; Cytochrome P-450 CYP3A; Dexamethasone; Female; Food-Drug Interactions; Ketoconazole; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Simvastatin

2013
Capsaicin induces metabolism of simvasatin in rat: involvement of upregulating expression of Ugt1a1.
    Die Pharmazie, 2016, Volume: 71, Issue:5

    Topics: Animals; Area Under Curve; Blotting, Western; Capsaicin; Chromatography, Liquid; Dose-Response Relationship, Drug; Female; Food-Drug Interactions; Glucuronosyltransferase; Liver; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Tandem Mass Spectrometry; Up-Regulation

2016