capsaicin has been researched along with sb 705498 in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, J; Guo, Y; Hu, X; Huang, H; Jin, Z; Li, Z; Liu, Z; Wang, K; Wang, Y; Zhang, L; Zhong, Y; Zong, X | 1 |
| Davis, JB; Fell, S; Gunthorpe, MJ; Jerman, JC; Rami, HK; Randall, AD; Sanderson, D; Sargent, B; Smart, D; Stemp, G; Stevens, AJ; Thompson, M | 1 |
| Arpino, S; Brough, S; Davis, JB; Egerton, J; Gunthorpe, MJ; Hannan, SL; Holland, VA; Jerman, JC; Lappin, SC; Rami, HK; Randall, A; Smart, D; Smith, GD; Thompson, M; Winborn, K; Wright, J | 1 |
| Conway, SJ | 1 |
| Aerssens, J; Boeckxstaens, GE; Bulmer, DC; de Hoogt, R; de Jonge, WJ; Klooker, TK; Lee, K; Peeters, PJ; Stanisor, OI; van den Wijngaard, RM; van der Coelen, D; Welting, O; Wouters, MM | 1 |
| Alenmyr, L; Andersson, M; Greiff, L; Högestätt, ED; Sterner, O; Zygmunt, PM | 1 |
| Biggadike, K; Busza, A; Campbell, S; Changani, K; Coe, D; Denyer, J; Dinnewell, L; Hotee, S; Lines, M; Pindoria, K; Saklatvala, P; Thompson, SA; Vitulli, G | 1 |
| Beerahee, M; Denyer, J; Fokkens, W; Holland, C; Newlands, A; Segboer, C; Smart, K; Terreehorst, I; Tsitoura, DC; van Drunen, C | 1 |
| Dockry, R; Holt, K; Kelsall, A; Khalid, S; Murdoch, R; Newlands, A; Smart, K; Smith, JA; Woodcock, A | 1 |
| Fernando, D; Gibson, RA; McCallum, S; Mistry, H; Robertson, J; Wyres, M; Yosipovitch, G | 1 |
| Bae, IH; Burns, A; Choi, G; Choi, JK; Fagg, R; Gatfield, KM; Lee, CS; Naidoo, AA; Park, M; Park, YH; Powell, AJ; Vidgeon-Hart, M | 1 |
| Liu, L; Sun, T; Wang, L; Zhang, L | 1 |
1 review(s) available for capsaicin and sb 705498
| Article | Year |
|---|---|
TRPing the switch on pain: an introduction to the chemistry and biology of capsaicin and TRPV1.
Topics: Animals; Benzimidazoles; Capsaicin; Humans; Ligands; Pyrrolidines; Sodium Channel Blockers; TRPV Cation Channels; Urea | 2008 |
4 trial(s) available for capsaicin and sb 705498
| Article | Year |
|---|---|
Effect of mucosal TRPV1 inhibition in allergic rhinitis.
Topics: Adult; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; Fluorometry; HEK293 Cells; Humans; Male; Pyrrolidines; Rhinitis, Allergic, Seasonal; TRPV Cation Channels; Urea; Young Adult | 2012 |
Inhibition of capsaicin-driven nasal hyper-reactivity by SB-705498, a TRPV1 antagonist.
Topics: Adolescent; Adult; Capsaicin; Double-Blind Method; Female; Humans; Male; Middle Aged; Pyrrolidines; Rhinitis; TRPV Cation Channels; Urea; Visual Analog Scale | 2014 |
Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial.
Topics: Administration, Inhalation; Adult; Aged; Animals; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Cross-Over Studies; Double-Blind Method; Female; Gene Expression; Humans; Male; Middle Aged; Pyrrolidines; Quality of Life; Severity of Illness Index; Treatment Outcome; TRPV Cation Channels; Urea | 2014 |
A randomised trial evaluating the effects of the TRPV1 antagonist SB705498 on pruritus induced by histamine, and cowhage challenge in healthy volunteers.
Topics: Administration, Topical; Adult; Capsaicin; Healthy Volunteers; Histamine; Humans; Male; Middle Aged; Pruritus; Pyrrolidines; Skin; TRPV Cation Channels; Urea | 2014 |
7 other study(ies) available for capsaicin and sb 705498
| Article | Year |
|---|---|
Optimization of 4-arylthiophene-3-carboxylic acid derivatives as inhibitors of ANO1: Lead optimization studies toward their analgesic efficacy for inflammatory pain.
Topics: Analgesics; Animals; Anoctamin-1; Carboxylic Acids; HEK293 Cells; Humans; Hyperalgesia; Mice; Neoplasm Proteins; Pain | 2022 |
Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development.
Topics: Administration, Oral; Animals; Capsaicin; Cell Line; Drug Design; Guinea Pigs; Humans; Molecular Structure; Pyrrolidines; Rats; Structure-Activity Relationship; TRPV Cation Channels; Urea | 2006 |
Characterization of SB-705498, a potent and selective vanilloid receptor-1 (VR1/TRPV1) antagonist that inhibits the capsaicin-, acid-, and heat-mediated activation of the receptor.
Topics: Acids; Animals; Binding, Competitive; Calcium Signaling; Capsaicin; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hot Temperature; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Molecular Structure; Neurons; Patch-Clamp Techniques; Pyrrolidines; Rats; Transfection; TRPV Cation Channels; Urea | 2007 |
Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats.
Topics: Animals; Blotting, Western; Capsaicin; Catheterization; Colon; Drinking Behavior; Female; Immunohistochemistry; Macrophages; Mast Cells; Maternal Deprivation; Nerve Growth Factor; Pregnancy; Pyrrolidines; Rats; Rats, Long-Evans; Stress, Psychological; T-Lymphocytes; Transcription, Genetic; TRPV Cation Channels; Urea | 2009 |
Effect of the TRPV1 antagonist SB-705498 on the nasal parasympathetic reflex response in the ovalbumin sensitized guinea pig.
Topics: Administration, Intranasal; Administration, Oral; Animals; Anti-Allergic Agents; Capsaicin; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Female; Guinea Pigs; Male; Nasal Mucosa; Parasympathetic Nervous System; Parasympatholytics; Particle Size; Pyrrolidines; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Secretory Pathway; Sensory System Agents; Trigeminal Ganglion; TRPV Cation Channels; Urea | 2013 |
Do TRPV1 antagonists increase the risk for skin tumourigenesis? A collaborative in vitro and in vivo assessment.
Topics: Acrylamides; Animals; Anthracenes; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cell Line; Cell Proliferation; Cell Survival; Cocarcinogenesis; Female; Humans; Keratinocytes; Mice; Mice, Hairless; Piperidines; Primary Cell Culture; Pyridines; Pyrrolidines; Risk; Skin Neoplasms; TRPV Cation Channels; Urea | 2018 |
The research of the possible mechanism and the treatment for capsaicin-induced cough.
Topics: Animals; Antitussive Agents; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Codeine; Cough; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Guinea Pigs; Male; Neurokinin A; Pyrrolidines; Substance P; TRPV Cation Channels; Urea | 2018 |