capsaicin has been researched along with neurokinin a in 206 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (15.53) | 18.7374 |
| 1990's | 122 (59.22) | 18.2507 |
| 2000's | 44 (21.36) | 29.6817 |
| 2010's | 5 (2.43) | 24.3611 |
| 2020's | 3 (1.46) | 2.80 |
| Authors | Studies |
|---|---|
| Krause, JE; Sivam, SP | 1 |
| Franco-Cereceda, A; Lou, YP; Lundberg, JM | 2 |
| Lou, YP; Lundberg, JM | 1 |
| Garland, A; Hershenson, MB; Hsiue, TR; Leff, AR; Ray, DW; Solway, J | 2 |
| Ellis, JL; Undem, BJ | 1 |
| Ballati, L; Evangelista, S; Manzini, S | 1 |
| Del Bianco, E; Giuliani, S; Maggi, CA; Santicioli, P | 1 |
| Yaksh, TL; Yamamoto, T | 1 |
| Lee, LY; Lou, YP; Lundberg, JM; Satoh, H | 2 |
| Giuliani, S; Maggi, CA; Santicioli, P; Theodorsson, E | 1 |
| Ballati, L; Evangelista, S; Maggi, CA; Manzini, S | 1 |
| Bonici, B; Cuiné, F; Faucher, DC; Garret, C; Laduron, PM; Le Prado, N; Moussaoui, SM | 1 |
| Fujii, T; Maeda, Y; Morimoto, H; Murai, M | 1 |
| Desmazes, N; Dusser, DJ; Lacroix, H; Lockhart, A | 1 |
| Ballati, L; Evangelista, S; Maggi, CA | 1 |
| Ahlstedt, S; Alving, K; Lundberg, JM; Nilsson, G | 1 |
| Moritoki, H; Takase, H; Tanioka, A | 1 |
| Cecconi, R; Geppetti, P; Maggi, CA; Meini, S; Nardi, M; Patacchini, R; Romani, A; Tramontana, M | 1 |
| Karlsson, JA; Kröll, F; Lundberg, JM; Persson, CG | 1 |
| Kangrga, I; Randic, M | 1 |
| Baroldi, P; Maggi, CA; Meli, A; Patacchini, R; Theodorsson, E | 1 |
| Jin, JG; Nakayama, S; Takaki, M | 1 |
| Amann, R; Donnerer, J; Giuliani, S; Lembeck, F; Maggi, CA | 1 |
| Couture, R; Jacques, L | 1 |
| Geppetti, P; Grassi, J; Maillet, S; Mantellini, P; Renzi, D; Santicioli, P; Surrenti, C; Theodorsson, E | 1 |
| Ingenito, EP; Ingram, RH; Martins, MA; Pliss, LB | 1 |
| Andrews, PV; Boyd, RL; Eglezos, A; Helme, RD | 1 |
| Alafaci, C; Edvinsson, L; Jansen, I; Uddman, R | 1 |
| Fujii, T; Kiyotoh, S; Morimoto, H; Murai, M; Nishikawa, M | 1 |
| Barnes, PJ; Kuo, HP; Rogers, DF; Rohde, JA; Tokuyama, K | 1 |
| Drazen, JM; Martins, MA; Shore, SA | 1 |
| Giuliani, S; Maggi, CA; Patacchini, R; Santicioli, P | 2 |
| Evangelista, S; Geppetti, P; Maggi, CA; Mantellini, P; Renzi, D; Santicioli, P; Surrenti, C | 1 |
| Myers, AC; Undem, BJ | 2 |
| Karanth, SS; Kuhn, DM; Levene, MM; Polak, JM; Springall, DR | 1 |
| Fujita, H; Kawabata, S; Kuraishi, Y; Matsumoto, T; Nakamura, A; Satoh, M | 1 |
| Luk, DE; Nolan, PN; Staszewska-Woolley, J | 1 |
| Franco-Cereceda, A | 1 |
| Boniotti, A; Fabbri, LM; Maggi, CA; Mapp, CE | 1 |
| Andersson, SE; Le Greves, P | 1 |
| Amerini, S; Filippi, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Alving, K; Lundberg, JM; Matran, R | 1 |
| Ahlstedt, S; Alving, K; Hökfelt, T; Lundberg, JM; Nilsson, G | 1 |
| Brodin, E; Hökfelt, T; Hua, XY; Lundberg, JM; Theodorsson-Norheim, E | 1 |
| Fischer, JA; Gamse, R; Lundberg, JM; Petermann, J; Saria, A; Theodorsson-Norheim, E | 1 |
| Gamse, R; Lundberg, JM; Saria, A; Theodorsson-Norheim, E | 2 |
| Kamiya, HO; Kuromizu, K; Masui, H; Nagashima, A; Takano, Y | 1 |
| Fujiwara, M; Muramatsu, I; Nakanishi, S; Taniguchi, T; Ueda, N | 1 |
| Brodin, E; Gamse, R; Hua, XY; Lundberg, JM; Saria, A; Theodorsson-Norheim, E | 1 |
| Hua, XY; Lundberg, JM | 1 |
| Foreman, JC | 1 |
| Abelli, L; Giuliani, S; Maggi, CA; Meli, A; Regoli, D; Santicioli, P | 1 |
| Fujiwara, M; Muramatsu, I; Nakanishi, S | 1 |
| Abelli, L; Capasso, M; Conte, B; Giuliani, S; Maggi, CA; Meli, A; Parlani, M; Santicioli, P | 1 |
| Dun, NJ; Lundberg, JM; Ma, RC; Saria, A; Theodorsson-Norheim, E | 1 |
| Gamse, R; Hua, XY; Lundberg, JM; Martling, CR; Saria, A; Theodorsson-Norheim, E | 1 |
| Ando, K; Ishida, Y; Iwamoto, T; Kanaya, J; Kitagawa, K; Moritoki, H | 1 |
| Andersson, SE | 1 |
| Alessandri, M; Amenta, F; Ballerini, G; Fanciullacci, M; Geppetti, P; Maggi, CA; Santicioli, P; Theodorsson-Norheim, E | 1 |
| Frilli, S; Furio, M; Fusco, B; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Santicioli, P; Theodorsson, E | 1 |
| Gamse, R; Lundberg, JM; Martling, CR; Saria, A; Theodorsson-Norheim, E; Yan, Z | 1 |
| Alm, P; Lundberg, LM | 1 |
| Maggi, CA; Meli, A; Patacchini, R; Renzi, D; Santicioli, P; Surrenti, C | 1 |
| Amann, R; Dray, A; Hankins, MW | 1 |
| Franco-Cereceda, A; Rudehill, A | 1 |
| Abelli, L; Conti, S; Del Bianco, E; Geppetti, P; Maggi, CA; Manzini, S; Somma, V | 1 |
| Del Bianco, E; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Baguñà, J; Romero, R; Saló, E | 1 |
| Bevis, P; Diez Guerra, FJ; Emson, PC; MacIntyre, I; Zaidi, M | 1 |
| Franco-Cereceda, A; Lundberg, JM | 1 |
| Franco-Cereceda, A; Lundberg, JM; Saria, A; Schreibmayer, W; Tritthart, HA | 1 |
| Brodin, E; Hua, XY; Lundberg, JM; Theodorsson-Norheim, E | 1 |
| Abelli, L; Giuliani, S; Maggi, CA; Meli, A; Santicioli, P | 1 |
| Hua, XY; Kinn, AC; Lundberg, JM | 1 |
| Håkanson, R; Wang, ZY | 1 |
| Hay, DW; Hubbard, WC; Undem, BJ | 1 |
| Advenier, C; Hirsch, A; Martin, CA; Molimard, M; Naline, E | 1 |
| Ballati, L; Evangelista, S; Manzini, S; Meini, S | 1 |
| Besson, G; Drazen, JM; Israel, E; Lilly, CM; Rodger, IW | 1 |
| Banasiak, D; Burcher, E | 1 |
| Barnes, PJ; Belvisi, MG; Maggi, CA; Patacchini, R | 1 |
| Hosoki, R; Kurihara, T; Otsuka, M; Saito, K; Suzuki, H; Urayama, O; Yanagisawa, M; Yoshioka, K | 1 |
| Bevan, S; Geppetti, P | 1 |
| Ballati, L; Boni, P; Evangelista, S | 1 |
| Chiba, Y; Misawa, M | 1 |
| Fernezlian, SM; Leme, AS; Maldonado, EA; Martins, MA; Perini, A; Saldiva, PH; Warth, Mdo P | 1 |
| Schneider, C; Spurlock, B; Stewart, NL; Szarek, JL | 1 |
| Brain, JD; Jimba, M; Killingsworth, CR; Long, NC; Shore, SA; Skornik, WA | 1 |
| Germonpre, PR; Joos, GF; Pauwels, RA | 1 |
| Dray, A; Maggi, CA; Nagy, I; Urban, L; Woolf, CJ | 1 |
| Mak, JC; Meini, S; Rogers, DF; Rohde, JA | 1 |
| Bevan, S; Giuliani, S; Maggi, CA; Rang, HP; Walpole, CS | 1 |
| Barnes, PJ; Hirayama, Y; Lei, YH; Rogers, DF | 1 |
| Advenier, C; Molimard, M | 1 |
| Advenier, C; Emonds-Alt, X; Qian, Y | 1 |
| Fujii, T; Hagiwara, D; Ikari, N; Maeda, Y; Matsuo, M; Miyake, H; Murai, M | 1 |
| Bertrand, C; Desai, MC; Geppetti, P; Nadel, JA; Piedimonte, G; Snider, RM | 1 |
| Boniotti, A; Chitano, P; Ciaccia, A; Coser, E; Di Stefano, A; Fabbri, LM; Mapp, CE; Papi, A; Saetta, M | 1 |
| Anding, P; Gao, XP; Lowe, J; Rennard, SI; Robbins, RA; Rubinstein, I; Snider, RM | 1 |
| Fuchikami, J; Isohama, Y; Kai, H; Miyata, T; Takahama, K | 1 |
| Hall, JM; Mitchell, D; Morton, IK | 1 |
| Fujii, T; Hagiwara, D; Maeda, Y; Matsuo, M; Miyake, H; Murai, M; Yamaoka, M | 1 |
| Garret, C; Giuliani, S; Lecci, A; Maggi, CA | 1 |
| Dray, A; Maggi, CA; Nagy, I; Urban, L | 1 |
| Bertrand, C; Geppetti, P; Graf, PD; Nadel, JA | 1 |
| Baugh, LE; Farrell, AM; Kudlacz, EM; Logan, DE; Shatzer, SA | 1 |
| Andersson, RG; Lindström, EG | 2 |
| Dougherty, PM; Palecek, J; Palecková, V; Willis, WD | 1 |
| Bannenberg, G; Kimland, M; Lundberg, JM; Moldéus, P; Ryrfeldt, A | 1 |
| Akao, N; Fujimura, M; Kondo, K; Matsuda, T; Ogawa, H; Saito, M | 1 |
| Bryce, DK; Desai, MC; Heym, J; Longo, KP; McLean, S; Rosen, T; Schmidt, AW; Snider, RM | 1 |
| Buckner, CK; Campbell, J; Dea, D; Krell, RD; Lengel, D; Liberati, N; Miller, S; Shenvi, A; Stinson-Fisher, C | 1 |
| Lou, YP; Lundberg, JM; Satoh, H | 1 |
| Doerfler, DL; Sailstad, DM; Selgrade, M; Veronesi, B | 1 |
| Bee, D; Crambes, O; Howard, P; Laude, EA | 1 |
| Hällgren, A; Hellström, PM; Lördal, M; Nylander, O | 1 |
| Back, SM; Hua, XY; Tam, EK | 1 |
| Advenier, C; Bakdach, H; Bonnet, PA; Cui, YY; Michel, A; Naline, E | 1 |
| Arakawa, M; Goto, F; Katori, M; Majima, M; Nagai, K | 1 |
| Baur, X; Marcynski, B; Marek, W; Potthast, JJ | 1 |
| Arai, Y; Higashide, Y; Nakajima, Y; Shibata, M; Yamaura, T; Yatabe, Y | 1 |
| Arai, Y; Higashide, Y; Shibata, M; Yamaura, T; Yatabe, Y | 1 |
| Bai, T; Knight, D; McKay, K; Schellenberg, RR; Wiggs, B | 1 |
| Holst, JJ; Schmidt, PT | 1 |
| Advenier, C; Crambes, O; Girard, V; Lundberg, JM; Malbezin, M; Malmström, RE; Naline, E | 1 |
| Fujii, T; Hirata, K; Kamoi, H; Kanazawa, H; Kawaguchi, T; Kudoh, S; Shoji, S; Yoshikawa, J | 1 |
| Ando, M; Fujii, K; Goto, E; Hamamoto, J; Hirata, N; Honda, I; Iwagoe, H; Kohrogi, H; Yamaguchi, T | 1 |
| Grattan, TJ; Laude, EA; Morice, AH; Wright, CE | 1 |
| MacNaughton, W; Moore, B; Vanner, S | 1 |
| Advenier, C; Canet, E; Félétou, M; Girard, V | 1 |
| Bullock, GR; Joos, GF; Lefebvre, RA; Pauwels, RA | 1 |
| Holst, JJ; Rasmussen, TN; Schmidt, PT | 2 |
| Bereiter, DA; Bereiter, DF; Maclean, DB; Tonnessen, BH | 1 |
| Dueck, R; Högman, M; Hua, XY; Reber, A; Yaksh, TL | 1 |
| Evangelista, S; Giachetti, A; Manzini, S; Paoli, S | 1 |
| Blackshaw, LA; Lynn, PA; Smid, SD; Templeman, R | 1 |
| Criscuoli, M; Giuliani, S; Lecci, A; Lippi, A; Maggi, CA; Patacchini, R; Santicioli, P; Tramontana, M | 1 |
| Colquhoun, EQ; Eldershaw, TP; Geraghty, DP; Griffiths, CD | 1 |
| Chen, HH; Kuo, HP | 1 |
| Fujiwara, H; Hirata, K; Kanazawa, H; Yoshikawa, J | 1 |
| Pierau, FK; Sann, H | 1 |
| Hageman, C; Högman, M; Hua, X | 1 |
| Fischer, A; Undem, BJ | 1 |
| Baroody, FM; Corey, JP; Gungor, A; Naclerio, RM; White, SR | 1 |
| Exintaris, B; Lang, RJ | 1 |
| Lee, LY; Wu, ZX | 1 |
| Coffa, FP; Kotecha, N | 1 |
| Geraghty, DP; Mazzone, SB | 2 |
| Holst, JJ; Poulsen, SS; Rasmussen, TN; Schmidt, PT; Tornøe, K | 1 |
| D'Agostino, G; Erbelding, D; Kilbinger, H | 1 |
| Chang, Y; Hancock, JC; Hoover, DB | 1 |
| Bergren, DR | 1 |
| Baird, AW; Goldhill, J; Moriarty, D; Selve, N | 1 |
| Ando, R; Kawamura, S; Sakurada, T; Watanabe, C; Yonezawa, A | 1 |
| Katzman, NJ; Lai, YL | 1 |
| Du, J; Haley, KJ; Karpitsky, VV; Krause, JE; Lilly, CM; Osathanondh, R; Sunday, ME; Vathanaprida, C | 1 |
| Araki, H; Arizono, N; Kakehi, K; Kawabata, A; Kinoshita, M; Kuroda, R; Nishida, M; Nishikawa, H; Oda, Y | 1 |
| Carstens, E; Dessirier, JM; Jinks, SL; Simons, CT | 1 |
| Baird, AW; Goldhill, J; Moriarty, D; O'Donoghue, DP; Selve, N | 1 |
| Giuliani, S; Lecci, A; Lippi, A; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
| Averbeck, B; Cirillo, R; Evangelista, S; Fetzer, S; Kress, M; Lippi, A; Maggi, CA; Manzini, S; Reeh, PW; Sauer, SK; Vieira, C | 1 |
| Inoue, M; Matsunaga, S; Mizuno, K; Rashid, MH; Sakurada, T; Takeshima, H; Ueda, H; Yoshida, A | 1 |
| Hataishi, R; Hayashi, I; Imasaki, T; Kobayashi, H; Majima, M; Tomita, T | 1 |
| Ansel, JC; Aranda, J; Armstrong, CA; Burbach, GJ; Caughman, SW; Kim, A; Kim, KH; Naik, SM; Wright, S; Zivony, AS | 1 |
| Hayashi, I; Kamijo, Y; Majima, M; Ohwada, T; Soma, K | 1 |
| Bartocci, C; Bolle, P; Tucci, P | 1 |
| Carini, F; Catalioto, RM; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
| Bolle, P; Evandri, MG; Tucci, P | 1 |
| Bayer, MK; Chavolla-Calderón, M; Fontán, JJ | 1 |
| Baamonde, A; Candenas, ML; Hidalgo, A; Pennefather, JN; Pintado, CO; Pinto, FM; Sanchez, T | 1 |
| Shea-Donohue, T; Zhao, A | 1 |
| Bolle, P; Severini, C; Tucci, P; Valeri, P | 1 |
| Cunha-Vaz, JG; Gaspar, MN; Macedo, TR; Ribeiro, CA | 1 |
| Lee, LY; Ruan, T; Wu, ZX; Yang, QH | 1 |
| Horie, S; Minowa, S; Murayama, T; Someya, A; Tsuchiya, S | 1 |
| Greenwood-Van Meerveld, B; Venkova, K | 1 |
| Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Yamashita, M | 1 |
| Arata, V; Kasahara, DI; Leick-Maldonado, EA; Martins, MA; Prado, CM; Tibério, IF | 1 |
| Doblinger, A; Dragosits, E; Fischer-Colbrie, R; Göttinger, W; Humpel, C; Kunze, C; Lalehabbasi, D; Laslop, A; Leierer, J; Philipp, W; Schmid, E; Teuchner, B; Theodorsson, E; Troger, J | 1 |
| Lao, L; Marvizón, JC | 1 |
| Smid, SD; Smith, AS | 1 |
| de Groat, WC; Sculptoreanu, A | 1 |
| Assini, JB; Blennerhassett, MG; Dilworth, N; Lourenssen, S; Miller, DV; Paterson, WG | 1 |
| Kasahara, DI; Leick-Maldonado, EA; Martins, MA; Miyamoto, L; Prado, CM; Tibério, IF; Yano, LM | 1 |
| Davidson, ME; Lang, RJ | 1 |
| Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Tsuchida, H; Yamashita, M | 1 |
| Aura Kullmann, F; de Groat, WC; Sculptoreanu, A | 1 |
| Hasan, W; McCarson, KE; Rook, JM | 1 |
| Horie, S; Hosoya, T; Kurosawa, E; Matsumoto, K; Murayama, T; Priestley, JV; Tashima, K; Terui, H | 1 |
| Blennerhassett, MG; Liu, H; Lourenssen, S; Miller, DV; Paterson, WG; Wells, RW | 1 |
| Akasaka, Y; Hatta, A; Inoue, H; Sakai, A; Suzuki, H; Takasu, K; Tsukahara, M | 1 |
| Calzetta, L; Capuano, A; Cazzola, M; Facciolo, F; Luongo, L; Maione, S; Matera, MG; Page, C; Rinaldi, B; Rogliani, P | 1 |
| Benemei, S; De Siena, G; Materazzi, S; Minocci, D; Nassini, R | 1 |
| Liu, L; Sun, T; Wang, L; Zhang, L | 1 |
| Dong, L; Fei, X; Liu, D; Yuan, J; Zhang, C; Zhou, Y; Zhu, Y; Zhu, Z | 1 |
| Chen, Z; Guo, L; Jin, XD; Li, Y; Liu, J; Shi, B; Wang, S; Xu, Y; Zhang, X; Zhao, M | 1 |
| Calzetta, L; Cito, G; Pistocchini, E; Ritondo, BL; Rogliani, P; Verri, S | 1 |
3 review(s) available for capsaicin and neurokinin a
| Article | Year |
|---|---|
Neuropeptides and the pathogenesis of allergy.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Hypersensitivity; Inflammation; Mast Cells; Neurokinin A; Neuropeptides; Peripheral Nerves; Substance P | 1987 |
Protons: small stimulants of capsaicin-sensitive sensory nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electrophysiology; Guinea Pigs; Neurokinin A; Neurons, Afferent; Protons; Rats; Ruthenium Red; Substance P | 1994 |
Efferent functions of C-fiber nociceptors.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Efferent Pathways; Fibromyalgia; Humans; Inflammation; Nerve Fibers; Neurokinin A; Nociceptors; Skin; Substance P; Swine | 1998 |
203 other study(ies) available for capsaicin and neurokinin a
| Article | Year |
|---|---|
Tachykinin systems in the spinal cord and basal ganglia: influence of neonatal capsaicin treatment or dopaminergic intervention on levels of peptides, substance P-encoding mRNAs, and substance P receptor mRNA.
Topics: Animals; Animals, Newborn; Basal Ganglia; Blotting, Northern; Capsaicin; Chromatography, High Pressure Liquid; Dopamine Agents; Dynorphins; Endorphins; Female; Haloperidol; Injections, Subcutaneous; Neurokinin A; Neurons; Neurotoxins; Pregnancy; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurotransmitter; RNA, Messenger; Spinal Cord; Substance P; Tachykinins | 1992 |
Different ion channel mechanisms between low concentrations of capsaicin and high concentrations of capsaicin and nicotine regarding peptide release from pulmonary afferents.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Capsaicin; Diterpenes; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Lung; Male; Nerve Endings; Neurokinin A; Neurons, Afferent; Nicotine; omega-Conotoxins; Peptides; Peptides, Cyclic; Tetrodotoxin; Vagus Nerve | 1992 |
Inhibition of low pH evoked activation of airway sensory nerves by capsazepine, a novel capsaicin-receptor antagonist.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Citrates; Citric Acid; Electric Stimulation; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Neurokinin A; Neurons, Afferent; Nicotine; Receptors, Drug; Respiratory Physiological Phenomena; Respiratory System; Ruthenium Red; Tidal Volume; Vagus Nerve | 1992 |
Endogenous sensory neuropeptide release enhances nonspecific airway responsiveness in guinea pigs.
Topics: Acetylcholine; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Leukocyte Count; Male; Nerve Fibers; Neurokinin A; Neurons, Afferent; Neuropeptides | 1992 |
Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea.
Topics: Animals; Antigens; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Nerve Fibers; Neurokinin A; Peptide Fragments; Prostaglandin D2; Pyrilamine; Serotonin; Tetrodotoxin; Trachea; Vagus Nerve | 1992 |
Repeated antigen challenge induced airway hyperresponsiveness to neurokinin A and vagal non-adrenergic, non-cholinergic (NANC) stimulation in guinea pigs.
Topics: Acetylcholine; Aerosols; Animals; Antigens; Bronchial Hyperreactivity; Capsaicin; Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Guinea Pigs; Histamine; Male; Neurokinin A; Neurons, Afferent; Receptors, Neurotransmitter; Receptors, Tachykinin; Sensitivity and Specificity; Vagus Nerve | 1992 |
Local motor responses to bradykinin and bacterial chemotactic peptide formyl-methionyl-leucyl-phenylalanine (FMLP) in the guinea-pig isolated renal pelvis and ureter.
Topics: Animals; Bradykinin; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indomethacin; Kidney Pelvis; Male; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Oligopeptides; Peptide Fragments; Ureter | 1992 |
Effects of intrathecal capsaicin and an NK-1 antagonist, CP,96-345, on the thermal hyperalgesia observed following unilateral constriction of the sciatic nerve in the rat.
Topics: Animals; Biphenyl Compounds; Capsaicin; Hot Temperature; Hypnotics and Sedatives; Injections, Spinal; Male; Neurokinin A; Neuropeptides; Nociceptors; Pain; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 1992 |
Inhibitory effects of capsazepine and the NK2 antagonist SR 48968 on bronchoconstriction evoked by sensory nerve stimulation in guinea-pigs.
Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Citrates; Citric Acid; Electric Stimulation; Female; Guinea Pigs; Male; Neurokinin A; Neurons, Afferent; Piperidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter | 1992 |
Tachykinins and calcitonin gene-related peptide as co-transmitters in local motor responses produced by sensory nerve activation in the guinea-pig isolated renal pelvis.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Kidney Pelvis; Male; Motor Neurons; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Neurotransmitter Agents; Peptide Fragments; Potassium Chloride; Radioimmunoassay; Tachykinins | 1992 |
Variable alpha 2-adrenoceptor-mediated inhibition of bronchoconstriction and peptide release upon activation of pulmonary afferents.
Topics: Adrenergic alpha-Agonists; Afferent Pathways; Animals; Bradykinin; Brimonidine Tartrate; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Diterpenes; Electric Stimulation; Guinea Pigs; Imidazoles; In Vitro Techniques; Lung; Neurokinin A; Nicotine; Peptides; Quinoxalines; Vagus Nerve | 1992 |
Effects of selective tachykinin receptor antagonists on capsaicin- and tachykinin-induced bronchospasm in anaesthetized guinea-pigs.
Topics: Anesthesia; Animals; Atropine; Biphenyl Compounds; Bronchial Spasm; Capsaicin; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Male; Neurokinin A; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Tachykinins | 1992 |
Distribution of neurokinin B in rat spinal cord and peripheral tissues: comparison with neurokinin A and substance P and effects of neonatal capsaicin treatment.
Topics: Animals; Animals, Newborn; Capsaicin; Ganglia, Spinal; Guinea Pigs; Male; Neurokinin A; Neurokinin B; Organ Specificity; Radioimmunoassay; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Substance P | 1992 |
Effects of the tripeptide substance P antagonist, FR113680, on airway constriction and airway edema induced by neurokinins in guinea-pigs.
Topics: Amino Acid Sequence; Animals; Bronchi; Bronchoconstriction; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; Kinins; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Oligopeptides; Pulmonary Edema; Substance P; Trachea | 1992 |
Carboxypeptidase M-like enzyme modulates the noncholinergic bronchoconstrictor response in guinea pig.
Topics: 3-Mercaptopropionic Acid; Animals; Bradykinin; Bronchoconstriction; Capsaicin; Electric Stimulation; GPI-Linked Proteins; Guinea Pigs; Histamine; Male; Metalloendopeptidases; Neurokinin A; Receptors, Cholinergic; Substance P; Vagus Nerve | 1992 |
Effect of ruthenium red on the bronchoconstriction induced by capsaicin and by selective tachykinin receptor agonists in anaesthetized guinea-pig.
Topics: Anesthesia; Animals; Bronchial Spasm; Bronchoconstriction; Capsaicin; Guanethidine; Guinea Pigs; Male; Neurokinin A; Peptide Fragments; Propranolol; Receptors, Neurotransmitter; Receptors, Tachykinin; Ruthenium Red | 1992 |
Local immune response and bronchial reactivity in rats after capsaicin treatment.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Capsaicin; Female; Injections, Subcutaneous; Lung; Male; Neurokinin A; Neuropeptide Y; Radioimmunoassay; Rats; Rats, Inbred BN | 1991 |
Dual effects of capsaicin on responses of the rabbit ear artery to field stimulation.
Topics: Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Ear, External; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vascular; Neurokinin A; Norepinephrine; Prostaglandins; Rabbits; Regional Blood Flow; Substance P; Sympathetic Nervous System; Synaptic Transmission | 1990 |
Effects of capsaicin, tachykinins, calcitonin gene-related peptide and bradykinin in the pig iris sphincter muscle.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Iris; Neurokinin A; Radioimmunoassay; Substance P; Swine; Tachykinins | 1990 |
Capsaicin-induced bronchoconstriction and neuropeptide release in guinea pig perfused lungs.
Topics: Acetylcholine; Adenosine; Airway Resistance; Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Interactions; Glycopeptides; Guinea Pigs; Hydrogen-Ion Concentration; Lung; Lung Compliance; Male; Neurokinin A; Neuropeptides; Substance P; Tetrodotoxin | 1990 |
Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice.
Topics: Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Neurokinin A; Rats; Rats, Inbred Strains; Recombinant Proteins; Spinal Cord; Spinal Nerve Roots; Substance P | 1990 |
Immunoblockade by a specific tachykinin antiserum of the non-cholinergic contractile responses in the guinea-pig isolated bronchus.
Topics: Airway Resistance; Animals; Bronchi; Capsaicin; Electric Stimulation; Eledoisin; Guinea Pigs; Immune Sera; In Vitro Techniques; Male; Muscle Contraction; Neurokinin A; Substance P | 1990 |
Capsaicin-sensitive and hexamethonium-insensitive circular muscle responses to mesenteric nerve stimulation in the isolated guinea pig ileum.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Substance P | 1990 |
Effects of carbonyl cyanide p-trichloromethoxyphenylhydrazone (CCCP) and of ruthenium red (RR) on capsaicin-evoked neuropeptide release from peripheral terminals of primary afferent neurones.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Nerve Endings; Neurokinin A; Neurons, Afferent; Neuropeptides; Nitriles; Rats; Ruthenium; Ruthenium Red; Urinary Bladder | 1990 |
Studies on the vascular permeability induced by intrathecal substance P and bradykinin in the rat.
Topics: Adrenalectomy; Animals; Blood Proteins; Bradykinin; Capillary Permeability; Capsaicin; Decerebrate State; In Vitro Techniques; Injections, Spinal; Male; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vagotomy | 1990 |
Enzyme immunoassay for tachykinin-like immunoreactivity in the guinea pig spinal cord.
Topics: Acetylcholinesterase; Animals; Capsaicin; Eledoisin; Guinea Pigs; Immunoenzyme Techniques; Kassinin; Male; Neurokinin A; Neurokinin B; Physalaemin; Potassium; Radioimmunoassay; Spinal Cord; Substance P; Tachykinins; Thiorphan | 1991 |
Effects of capsaicin on mechanical, cellular, and mediator responses to antigen in sensitized guinea pigs.
Topics: Animals; Antigens; Bronchoalveolar Lavage Fluid; Capsaicin; Guinea Pigs; Histamine; Immunization; Leukotrienes; Lung Compliance; Male; Neurokinin A; Ovalbumin; Prostaglandins; Substance P; Thromboxane B2 | 1991 |
Tachykinin-mediated modulation of the primary antibody response in rats: evidence for mediation by an NK-2 receptor.
Topics: Animals; Animals, Newborn; Antibody Formation; Capsaicin; Denervation; Female; Immune System; Lymph Nodes; Male; Neurokinin A; Peptide Fragments; Peripheral Nerves; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tachykinins | 1991 |
Evidence that calcitonin gene-related peptide contributes to the capsaicin-induced relaxation of guinea pig cerebral arteries.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Arteries; Guinea Pigs; Immunohistochemistry; Muscle Relaxation; Muscle, Smooth, Vascular; Neurokinin A; Substance P; Vasodilation | 1990 |
Effects of actinomycin D on airway constriction induced by tachykinins and capsaicin in guinea-pigs.
Topics: Airway Resistance; Animals; Capsaicin; Dactinomycin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Male; Neurokinin A; Substance P; Tachykinins; Trachea | 1991 |
Capsaicin and sensory neuropeptide stimulation of goblet cell secretion in guinea-pig trachea.
Topics: Anesthesia, General; Animals; Axons; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Exocrine Glands; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Neuropeptides; Substance P; Time Factors; Trachea | 1990 |
Capsaicin-induced release of tachykinins: effects of enzyme inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Capsaicin; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Lung; Male; Neprilysin; Neurokinin A; Perfusion; Substance P | 1991 |
Tachykinin antagonists and capsaicin-induced contraction of the rat isolated urinary bladder: evidence for tachykinin-mediated cotransmission.
Topics: Adenosine Triphosphate; Animals; Bombesin; Capsaicin; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Rats; Rats, Inbred Strains; Receptors, Purinergic; Substance P; Synaptic Transmission; Tachykinins; Urinary Bladder | 1991 |
Capsaicin-induced release of neurokinin A from muscle and mucosa of gastric corpus: correlation with capsaicin-evoked release of calcitonin gene-related peptide.
Topics: Animals; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Mucosa; Immunoenzyme Techniques; Male; Muscles; Neurokinin A; Radioimmunoassay; Rats; Rats, Inbred Strains; Staining and Labeling; Stomach; Substance P | 1991 |
Functional interactions between capsaicin-sensitive and cholinergic nerves in the guinea pig bronchus.
Topics: Animals; Atropine; Bronchi; Bronchoconstriction; Capsaicin; Cholinergic Fibers; Electric Stimulation; Guinea Pigs; Male; Neurokinin A; Neurons, Afferent; Substance P; Vagus Nerve | 1991 |
An immunocytochemical study of cutaneous innervation and the distribution of neuropeptides and protein gene product 9.5 in man and commonly employed laboratory animals.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Fluorescent Antibody Technique; Guinea Pigs; Humans; Neurokinin A; Neuropeptides; Oxidopamine; Rats; Rats, Inbred Strains; Skin; Substance P; Swine; Ubiquitin Thiolesterase | 1991 |
Involvement of substance P in hyperalgesia induced by intrathecal galanin.
Topics: Animals; Antibodies, Monoclonal; Behavior, Animal; Capsaicin; Carrageenan; Galanin; Guinea Pigs; Ileum; In Vitro Techniques; Inflammation; Injections, Spinal; Male; Muscle, Smooth; Neurokinin A; Nociceptors; Pain; Peptides; Rats; Rats, Inbred Strains; Substance P | 1991 |
Studies of reflexogenic effects of capsaicin and neuropeptides on neural afferents in the dog parietal pericardium.
Topics: Afferent Pathways; Animals; Arachidonic Acid; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Denervation; Dogs; Female; Heart Rate; Male; Neurokinin A; Neurokinin B; Neuropeptides; Pentolinium Tartrate; Pericardium; Propranolol; Substance P | 1991 |
Resiniferatoxin-, capsaicin- and CGRP-evoked porcine coronary vasodilatation is independent of EDRF mechanisms but antagonized by CGRP(8-37).
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Dactinomycin; Diterpenes; Methylene Blue; Neurokinin A; Nitric Oxide; Peptide Fragments; Substance P; Vasodilation | 1991 |
Prostacyclin activates tachykinin release from capsaicin-sensitive afferents in guinea-pig bronchi through a ruthenium red-sensitive pathway.
Topics: Animals; Bronchi; Capsaicin; Epoprostenol; Guinea Pigs; In Vitro Techniques; Indicators and Reagents; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Neurotransmitter Agents; Peptide Fragments; Ruthenium Red; Tachykinins | 1991 |
Ruthenium red and capsaicin induce a neurogenic inflammatory response in the rabbit eye: effects of omega-conotoxin GVIA and tetrodotoxin.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Capsaicin; Eye; Female; Inflammation; Intraocular Pressure; Male; Miosis; Neurokinin A; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic; Rabbits; Ruthenium Red; Substance P; Tetrodotoxin | 1991 |
Modulation by adrenergic transmitters of the efferent function of capsaicin-sensitive nerves in cardiac tissue.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Conduction System; Imidazoles; In Vitro Techniques; Male; Myocardial Contraction; Neurokinin A; Neurons, Afferent; Neuropeptide Y; Norepinephrine; Phenoxybenzamine; Substance P | 1991 |
Capsaicin-induced local effector responses, autonomic reflexes and sensory neuropeptide depletion in the pig.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Blood Proteins; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Catecholamines; Heart Rate; Hydrocortisone; Injections, Intravenous; Injections, Subcutaneous; Neurokinin A; Neuropeptide Y; Neuropeptides; Reflex; Swine; Time Factors; Vasoactive Intestinal Peptide; Vasodilation | 1991 |
Peptidergic innervation of rat lymphoid tissue and lung: relation to mast cells and sensitivity to capsaicin and immunization.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Immunization; Immunohistochemistry; Lung; Lymph Nodes; Lymphoid Tissue; Male; Mast Cells; Neurokinin A; Neuropeptide Y; Neuropeptides; Rats; Serotonin; Spleen; Tachykinins | 1990 |
Multiple tachykinins (neurokinin A, neuropeptide K and substance P) in capsaicin-sensitive sensory neurons in the guinea-pig.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fluorescent Antibody Technique; Guinea Pigs; Nerve Tissue Proteins; Neurokinin A; Neurons, Afferent; Radioimmunoassay; Substance P; Tachykinins; Terminology as Topic; Tissue Distribution | 1985 |
Simultaneous release of several tachykinins and calcitonin gene-related peptide from rat spinal cord slices.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; Female; In Vitro Techniques; Male; Nerve Tissue Proteins; Neurokinin A; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1986 |
Behavioral and neurochemical changes after intracisternal capsaicin treatment of the guinea pig.
Topics: Animals; Behavior, Animal; Capsaicin; Female; Guinea Pigs; Injections, Intraventricular; Male; Medulla Oblongata; Nasal Mucosa; Nerve Tissue Proteins; Neurokinin A; Substance P; Time Factors; Trigeminal Nucleus, Spinal | 1986 |
Distribution of substance K (neurokinin A) in the brain and peripheral tissues of rats.
Topics: Animals; Capsaicin; Central Nervous System; Chromatography, High Pressure Liquid; Female; Ileum; Male; Nerve Tissue Proteins; Neurokinin A; Radioimmunoassay; Rats; Rats, Inbred Strains; Submandibular Gland; Substance P; Vas Deferens | 1986 |
Effects of neurokinin A, substance P and electrical stimulation on the rabbit iris sphincter muscle.
Topics: Amino Acid Sequence; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Neurokinin A; Neuropeptides; Rabbits; Substance P | 1986 |
Capsaicin induced release of multiple tachykinins (substance P, neurokinin A and eledoisin-like material) from guinea-pig spinal cord and ureter.
Topics: Animals; Capsaicin; Eledoisin; Female; Guinea Pigs; Male; Neurokinin A; Neuropeptides; Proteinuria; Radioimmunoassay; Spinal Cord; Substance P; Tachykinins; Ureter | 1986 |
Dual capsaicin effects on ureteric motility: low dose inhibition mediated by calcitonin gene-related peptide and high dose stimulation by tachykinins?
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemodynamics; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Neurokinin A; Neuropeptides; Substance P; Tachykinins; Ureter | 1986 |
Further studies on the mechanisms of the tachykinin-induced activation of micturition reflex in rats: evidence for the involvement of the capsaicin-sensitive bladder mechanoreceptors.
Topics: Aging; Animals; Capsaicin; Diphenhydramine; Electric Stimulation; In Vitro Techniques; Indomethacin; Kassinin; Male; Mechanoreceptors; Neurokinin A; Neurokinin B; Neuropeptides; Oligopeptides; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder; Urination | 1987 |
Comparison of the responses to the sensory neuropeptides, substance P, neurokinin A, neurokinin B and calcitonin gene-related peptide and to trigeminal nerve stimulation in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Eledoisin; Female; Iris; Kinins; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Neuropeptides; Physalaemin; Potassium Chloride; Rabbits; Substance P; Trigeminal Nerve | 1987 |
Regional differences in the effects of capsaicin and tachykinins on motor activity and vascular permeability of the rat lower urinary tract.
Topics: Animals; Capillary Permeability; Capsaicin; Electric Stimulation; Evans Blue; Ganglia; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neuropeptides; Rats; Rats, Inbred Strains; Substance P; Urinary Tract | 1987 |
Neurokinin A in capsaicin-sensitive neurons of the guinea-pig inferior mesenteric ganglia: an additional putative mediator for the non-cholinergic excitatory postsynaptic potential.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Electrophysiology; Female; Ganglia, Sympathetic; Guinea Pigs; Male; Neurokinin A; Neuropeptides; Neurotransmitter Agents; Radioimmunoassay; Substance P; Synaptic Transmission | 1987 |
Coexisting peptides in capsaicin-sensitive sensory neurons: release and actions in the respiratory tract of the guinea-pig.
Topics: Animals; Capsaicin; Guinea Pigs; In Vitro Techniques; Lung; Muscle Contraction; Neurokinin A; Neuropeptides; Perfusion; Substance P; Trachea; Vasodilation | 1987 |
Capsaicin enhances the non-adrenergic twitch response of rat vas deferens.
Topics: Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Hydroxydopamines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neuropeptides; Norepinephrine; Oxidopamine; Peptides; Rats; Rats, Inbred Strains; Reserpine; Substance P; Vas Deferens | 1987 |
Responses to antidromic trigeminal nerve stimulation, substance P, NKA, CGRP and capsaicin in the rat eye.
Topics: Animals; Aqueous Humor; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Male; Neurokinin A; Neuropeptides; Pupil; Rats; Rats, Inbred Strains; Substance P; Trigeminal Nerve | 1987 |
Capsaicin-sensitive tachykinin-like immunoreactivity in the thymus of rats and guinea-pigs.
Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Cricetinae; Eledoisin; Guinea Pigs; Immunologic Techniques; Mice; Neurokinin A; Neurokinin B; Neuropeptides; Rats; Species Specificity; Substance P; Tachykinins; Thymus Gland | 1988 |
Tachykinin-like immunoreactivity in the mammalian urinary bladder: correlation with the functions of the capsaicin-sensitive sensory nerves.
Topics: Animals; Capsaicin; Guinea Pigs; Male; Mice; Muscle Contraction; Neurokinin A; Neurons, Afferent; Neuropeptides; Phenoxybenzamine; Rats; Rats, Inbred Strains; Species Specificity; Substance P; Tachykinins; Urinary Bladder | 1988 |
Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation.
Topics: Animals; Bradykinin; Capsaicin; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Nervous System; Neurokinin A; Pulmonary Artery; Sensation; Substance P; Tachykinins; Trachea; Vagus Nerve | 1988 |
Co-existence and origin of peptidergic and adrenergic nerves in the guinea pig uterus. Retrograde tracing and immunocytochemistry, effects of chemical sympathectomy, capsaicin treatment and pregnancy.
Topics: Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cervix Uteri; Female; Fluorescent Antibody Technique; Ganglia, Spinal; Guinea Pigs; Hydroxydopamines; Immunohistochemistry; Neurokinin A; Neuropeptide Y; Neuropeptides; Oxidopamine; Pregnancy; Substance P; Swine; Sympathectomy, Chemical; Uterus | 1988 |
Release of substance P- and calcitonin gene-related peptide-like immunoreactivity and motor response of the isolated guinea pig gallbladder to capsaicin.
Topics: Animals; Atropine; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neuropeptides; Substance P | 1989 |
Stimulation of afferent fibres of the guinea-pig ureter evokes potentials in inferior mesenteric ganglion neurones.
Topics: Animals; Capsaicin; Female; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Nerve Fibers; Neurokinin A; Neurons; Neurons, Afferent; Substance P; Time Factors; Ureter | 1988 |
Capsaicin-induced vasodilatation of human coronary arteries in vitro is mediated by calcitonin gene-related peptide rather than substance P or neurokinin A.
Topics: Adult; Arteries; Biological Factors; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Female; Humans; Male; Muscle, Smooth, Vascular; Neurokinin A; Neuropeptides; Nitric Oxide; Somatostatin; Substance P; Vasoactive Intestinal Peptide; Vasodilator Agents | 1989 |
Regional differences in the motor and inflammatory responses to capsaicin in guinea pig airways. Correlation with content and release of substance P-like immunoreactivity.
Topics: Animals; Biomarkers; Blood Proteins; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Guinea Pigs; Male; Muscle Contraction; Neurokinin A; Neurons, Afferent; Respiratory Muscles; Substance P; Trachea | 1989 |
The 'efferent' function of capsaicin-sensitive nerves: ruthenium red discriminates between different mechanisms of activation.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Male; Nerve Endings; Neurokinin A; Neurons, Efferent; Potassium Chloride; Ruthenium; Ruthenium Red | 1989 |
Effects of activators and antagonists of the neuropeptides substance P and substance K on cell proliferation in planarians.
Topics: Animals; Capsaicin; Cell Division; Epidermal Growth Factor; Models, Biological; Neurokinin A; Planarians; Substance P; Turbellaria | 1989 |
Evidence for release of calcitonin gene-related peptide and neurokinin A from sensory nerve endings in vivo.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Ganglia, Spinal; Immunohistochemistry; Male; Nerve Endings; Neurokinin A; Neurons, Afferent; Neuropeptides; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
Actions of calcitonin gene-related peptide and tachykinins in relation to the contractile effects of capsaicin in the guinea-pig and rat heart in vitro.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colforsin; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Neurokinin A; Neuropeptides; Norepinephrine; Rats; Vasodilator Agents | 1988 |
Calcitonin gene-related peptide: release by capsaicin and prolongation of the action potential in the guinea-pig heart.
Topics: Action Potentials; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cardiotonic Agents; Female; Guinea Pigs; Heart; Myocardial Contraction; Myocardium; Neurokinin A; Neuropeptide Y; Neuropeptides; Perfusion | 1988 |
Capsaicin treatment decreases tissue levels of neurokinin A-like immunoreactivity in the guinea pig.
Topics: Animals; Capsaicin; Guinea Pigs; Heart Atria; Ileum; Lung; Nerve Tissue Proteins; Neurokinin A; Tachykinins; Ureter | 1985 |
The motor effect of the capsaicin-sensitive inhibitory innervation of the rat ureter.
Topics: Animals; Capsaicin; Electric Stimulation; In Vitro Techniques; Kassinin; Male; Muscle Contraction; Neurokinin A; Neuropeptides; Oligopeptides; Rats; Tetrodotoxin; Ureter | 1986 |
Capsaicin-sensitive nerves and ureteric motility: opposing effects of tachykinins and calcitonin gene-related peptide.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Neurokinin A; Neurons, Afferent; Neuropeptides; Peptides; Uterine Contraction | 1986 |
Release of substance P- and substance K-like immunoreactivities from the isolated perfused guinea-pig lung.
Topics: Animals; Capsaicin; Female; Guinea Pigs; In Vitro Techniques; Irritants; Lung; Male; Nerve Tissue Proteins; Neurokinin A; Perfusion; Radioimmunoassay; Substance P | 1984 |
Effects of ruthenium red and capsazepine on C-fibres in the rabbit iris.
Topics: Animals; Bradykinin; Capsaicin; Drug Interactions; Electric Stimulation; Female; Iris; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Neurokinin A; Neuromuscular Junction; Rabbits; Ruthenium Red | 1993 |
Relative contributions of direct and indirect mechanisms mediating endothelin-induced contraction of guinea-pig trachea.
Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dicarboxylic Acids; Endothelins; Epithelium; Guinea Pigs; Histamine Release; In Vitro Techniques; Kinetics; Leukotriene Antagonists; Male; Muscle Contraction; Neurokinin A; Piperidines; Prostaglandins; Receptors, Tachykinin; SRS-A; Tetrodotoxin; Trachea | 1993 |
Electrophysiological effects of tachykinins and capsaicin on guinea-pig bronchial parasympathetic ganglion neurones.
Topics: Animals; Bronchi; Capsaicin; Electrophysiology; Ganglia, Parasympathetic; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Tachykinins | 1993 |
Contractile effects of bradykinin on the isolated human small bronchus.
Topics: Acetylcholine; Aged; Atropine; Benzamides; Biphenyl Compounds; Bradykinin; Bronchi; Bronchoconstriction; Capsaicin; Humans; In Vitro Techniques; Indomethacin; Middle Aged; Muscle, Smooth; Nerve Fibers; Neurokinin A; Neurons, Afferent; Piperidines; Receptors, Bradykinin; Ruthenium Red; Tetrodotoxin | 1994 |
Isbufylline, a xanthine derivative, inhibits bronchoconstrictor responses produced by stimulation of capsaicin-sensitive sensory nerves in guinea-pig: 'In vitro' and 'in vivo' evidence.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Capsaicin; Carbachol; Choline; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Neurons, Afferent; Stimulation, Chemical; Theophylline; Trachea; Vagus Nerve | 1993 |
Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs.
Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Perfusion; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Trachea | 1994 |
Effect of capsaicin on distribution of binding sites for tachykinins and calcitonin gene-related peptide in rat urinary bladder: a quantitative autoradiographic study.
Topics: Animals; Autoradiography; Calcitonin Gene-Related Peptide; Capsaicin; Male; Neurokinin A; Protein Binding; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Tachykinin; Substance P; Tissue Distribution; Urinary Bladder | 1994 |
Facilitatory effects of selective agonists for tachykinin receptors on cholinergic neurotransmission: evidence for species differences.
Topics: Adult; Amino Acid Sequence; Animals; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Parasympathetic Nervous System; Peptide Fragments; Rabbits; Receptors, Tachykinin; Substance P; Sulfones; Synaptic Transmission; Tachykinins | 1994 |
Involvement of enzymatic degradation in the inactivation of tachykinin neurotransmitters in neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; Electrophysiology; Endopeptidases; In Vitro Techniques; Membranes; Motor Neurons; Naloxone; Neurokinin A; Protease Inhibitors; Rats; Rats, Wistar; Spinal Cord; Substance P; Synaptic Membranes | 1994 |
Tachykinin NK1 and NK2 receptors mediate the non-cholinergic bronchospastic response to capsaicin and vagal stimulation in guinea-pigs.
Topics: Animals; Biphenyl Compounds; Bronchial Spasm; Capsaicin; Electric Stimulation; Guinea Pigs; Insufflation; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Vagus Nerve | 1995 |
Inhibition of neutral endopeptidase increases airway responsiveness to ACh in nonsensitized normal rats.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bronchial Hyperreactivity; Capillary Permeability; Capsaicin; Carbachol; Glycopeptides; In Vitro Techniques; Male; Muscle, Smooth; Neprilysin; Neurokinin A; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Respiratory System; Substance P; Vagotomy | 1995 |
Neurokinin depletion attenuates pulmonary changes induced by antigen challenge in sensitized guinea pigs.
Topics: Animals; Antigens; Capsaicin; Guinea Pigs; Immunization; Immunoglobulin E; Immunoglobulin G; Lung; Male; Neurokinin A; Ovalbumin; Substance P | 1995 |
Sensory nerve- and neuropeptide-mediated relaxation responses in airways of Sprague-Dawley rats.
Topics: Animals; Bethanechol; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Neuropeptides; Rats; Rats, Sprague-Dawley; Substance P; Tetrodotoxin; Trachea | 1995 |
Role of C fibers in physiological responses to ozone in rats.
Topics: Aerosols; Animals; Animals, Newborn; Body Temperature; Capsaicin; Female; Heart Rate; Lung Compliance; Male; Methacholine Chloride; Nerve Fibers; Neurokinin A; Ozone; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Substance P | 1995 |
Neurogenic inflammation in human airways: is it important?
Topics: Administration, Topical; Airway Resistance; Animals; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Humans; Nasal Mucosa; Neprilysin; Neurokinin A; Rhinitis, Allergic, Seasonal; Substance P | 1995 |
The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biphenyl Compounds; Capsaicin; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurokinin A; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Spinal Cord; Substance P; Synapses; Synaptic Transmission | 1993 |
Tachykinin control of ferret airways: mucus secretion, bronchoconstriction and receptor mapping.
Topics: Animals; Bronchoconstriction; Capsaicin; Ferrets; Male; Methacholine Chloride; Mucus; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Reproducibility of Results; Stimulation, Chemical; Substance P; Tachykinins; Trachea | 1993 |
A comparison of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Rats; Rats, Wistar; Ruthenium Red; Urinary Bladder; Vas Deferens | 1993 |
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo.
Topics: Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Dipeptides; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Hypotension; Indoles; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Smoking; Substance P; Vagus Nerve | 1993 |
Effect of frusemide on bradykinin- and capsaicin-induced contraction of the guinea-pig trachea.
Topics: Animals; Bradykinin; Bronchoconstriction; Capsaicin; Furosemide; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Substance P; Trachea | 1993 |
Effects of capsaicin, (+/-)-CP-96,345 and SR 48968 on the bradykinin-induced airways microvascular leakage in guinea-pigs.
Topics: Animals; Autonomic Nervous System; Benzamides; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Evans Blue; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Nerve Endings; Neurokinin A; Piperidines; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Effects of an NK1 receptor antagonist, FK888, on constriction and plasma extravasation induced in guinea pig airway by neurokinins and capsaicin.
Topics: Animals; Capillary Permeability; Capsaicin; Dipeptides; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Trachea | 1993 |
A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline.
Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hypertonic Solutions; Neurokinin A; Neurons, Afferent; Piperidines; Platelet Activating Factor; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Tachykinin; Sodium Chloride; Stimulation, Chemical; Substance P; Trachea; Tracheal Diseases | 1993 |
The effect of compound 48/80 on contractions induced by toluene diisocyanate in isolated guinea-pig bronchus.
Topics: Animals; Bronchoconstriction; Capsaicin; Cell Degranulation; Glycopeptides; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Ruthenium Red; Toluene 2,4-Diisocyanate | 1993 |
Impaired sensorineural function after allergen-induced mediator release.
Topics: Acetylcholine; Airway Resistance; Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Carbon Dioxide; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Male; Neurokinin A; Neurotransmitter Agents; Ovalbumin; Respiration Disorders; Substance P; Tidal Volume | 1993 |
NK1 receptors mediate tachykinin-induced increase in microvascular clearance in hamster cheek pouch.
Topics: Animals; Biphenyl Compounds; Capsaicin; Cheek; Cricetinae; Macromolecular Substances; Male; Mesocricetus; Microcirculation; Neurokinin A; Neurokinin B; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tachykinins | 1993 |
Neurokinin A, but not neurokinin B and substance P, induces codeine-resistant coughs in awake guinea-pigs.
Topics: Animals; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Drug Resistance; Guinea Pigs; Male; Neurokinin A; Neurokinin B; Substance P | 1993 |
Does substance P release mediate NANC nerve-mediated responses to field stimulation and ligands, in the rabbit isolated sphincter pupillae?
Topics: Animals; Bradykinin; Capsaicin; Electric Stimulation; Isometric Contraction; Male; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Physalaemin; Pupil; Rabbits; Receptors, Tachykinin; Structure-Activity Relationship; Substance P; Tachykinins | 1993 |
The pharmacological properties of FK888, a novel dipeptide NK1 antagonist.
Topics: Animals; Bronchoconstriction; Capsaicin; Cell Membrane; Dipeptides; Edema; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Indoles; Kinetics; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-1; Substance P | 1993 |
Spinal effects of selective NK-1 and NK-2 receptor antagonists on bladder motility in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Afferent Pathways; Animals; Capsaicin; Indoles; Isoindoles; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Reflex; Spinal Cord; Substance P; Urinary Bladder; Urination | 1993 |
The effects of NK-1 and NK-2 receptor antagonists on the capsaicin evoked synaptic response in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biphenyl Compounds; Capsaicin; In Vitro Techniques; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Spinal Cord; Substance P; Synapses | 1993 |
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors.
Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1993 |
Tachykinin-mediated respiratory effects in conscious guinea pigs: modulation by NK1 and NK2 receptor antagonists.
Topics: Aerosols; Animals; Biphenyl Compounds; Capsaicin; Cell Membrane; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuropeptides; Receptors, Neurokinin-2; Respiration; Substance P; Tachykinins | 1993 |
Morphine modulates contractile responses and neurokinin A-LI release elicited by electrical field stimulation or capsaicin in a guinea pig bronchial-tube preparation.
Topics: Animals; Bronchoconstriction; Capsaicin; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Morphine; Naloxone; Neurokinin A | 1995 |
Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin.
Topics: Animals; Biphenyl Compounds; Capsaicin; Female; Ganglia, Spinal; Injections, Intradermal; Macaca fascicularis; Male; Mechanoreceptors; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurons; Nociceptors; Pain Threshold; Peptide Fragments; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Skin; Spinothalamic Tracts; Synaptic Transmission | 1994 |
Sensory neuropeptide-mediated bronchoconstriction of the guinea pig lung by diamide; a comparison to hydrogen peroxide.
Topics: Animals; Benzamides; Biphenyl Compounds; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Carbazoles; Diamide; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Lung; Male; Neurokinin A; Neurons, Afferent; Neuropeptides; Piperidines; Thromboxanes | 1994 |
The effect of the neurokinin antagonist FK-224 on the cough response to inhaled capsaicin in a new model of guinea-pig eosinophilic bronchitis induced by intranasal polymyxin B.
Topics: Administration, Inhalation; Administration, Intranasal; Animals; Bronchial Provocation Tests; Bronchitis; Bronchoalveolar Lavage Fluid; Capsaicin; Cough; Eosinophilia; Guinea Pigs; Male; Neurokinin A; Peptides, Cyclic; Polymyxin B; Tachykinins | 1994 |
CP-99,994, a nonpeptide antagonist of the tachykinin NK1 receptor.
Topics: Albuterol; Animals; Binding, Competitive; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Kinetics; Lung; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Thiorphan; Verapamil | 1993 |
Differential blockade by tachykinin NK1 and NK2 receptor antagonists of bronchoconstriction induced by direct-acting agonists and the indirect-acting mimetics capsaicin, serotonin and 2-methyl-serotonin in the anesthetized guinea pig.
Topics: Amino Acid Sequence; Anesthesia; Animals; Benzamides; Biphenyl Compounds; Bronchial Spasm; Bronchoconstriction; Capsaicin; Guinea Pigs; Hypnotics and Sedatives; Injections, Intravenous; Male; Molecular Sequence Data; Neurokinin A; Piperidines; Receptors, Tachykinin; Serotonin | 1993 |
Postjunctional inhibitory effect of the NK2 receptor antagonist, SR 48968, on sensory NANC bronchoconstriction in the guinea-pig.
Topics: Animals; Atropine; Autonomic Nervous System; Benzamides; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Lung; Male; Neurokinin A; Neurons, Afferent; Neuropeptides; Piperidines; Receptors, Neurotransmitter; Receptors, Tachykinin | 1993 |
Inhibitory effects of capsazepine and SR 48968 on citric acid-induced bronchoconstriction in guinea-pigs.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Benzamides; Bronchoconstriction; Capsaicin; Citrates; Citric Acid; Female; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; Male; Neurokinin A; Neurons, Afferent; Piperidines | 1993 |
Neuropeptide modulation of chemically induced skin irritation.
Topics: Administration, Cutaneous; Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dose-Response Relationship, Drug; Ear, External; Female; Irritants; Mice; Mice, Inbred BALB C; Neurokinin A; Neuropeptides; Piperidines; Skin; Substance P; Synaptic Transmission | 1995 |
Antitussive and antibronchoconstriction actions of fenspiride in guinea-pigs.
Topics: Acetates; Acetic Acid; Aerosols; Airway Resistance; Animals; Antitussive Agents; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neurokinin A; Spiro Compounds; Substance P | 1995 |
Tachykinins increase vascular permeability in the gastrointestinal tract of the rat.
Topics: Animals; Capsaicin; Digestive System; Dose-Response Relationship, Drug; Duodenum; Hydrochloric Acid; Male; Neurokinin A; Permeability; Rats; Rats, Sprague-Dawley; Stomach; Tachykinins | 1996 |
Substance P enhances electrical field stimulation-induced mast cell degranulation in rat trachea.
Topics: Animals; Biphenyl Compounds; Capsaicin; Cell Degranulation; Chymotrypsin; Dose-Response Relationship, Drug; Electric Stimulation; Indomethacin; Male; Mast Cells; Neurokinin A; Neurokinin-1 Receptor Antagonists; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Substance P; Trachea | 1996 |
Effects of SCA40 on human bronchi and on guinea pig main bronchi in vitro. Comparison with cromakalim.
Topics: Acetylcholine; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Capsaicin; Charybdotoxin; Cromakalim; Electric Stimulation; Female; Glyburide; Guinea Pigs; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Nitroprusside; Osmolar Concentration; Parasympatholytics; Potassium Channel Blockers; Potassium Channels; Pyrazines; Pyrroles; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Role of tachykinins in enhancement of bradykinin-induced bronchoconstriction by captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Bradykinin; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Male; Neurokinin A; Peptides, Cyclic; Piperidines; Substance P | 1996 |
Role of substance P and neurokinin A in toluene diisocyanate-induced increased airway responsiveness in rabbits.
Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Animals; Bronchi; Bronchoconstriction; Capsaicin; Disease Models, Animal; Lung Diseases; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Occupational Diseases; Rabbits; Receptors, Neurokinin-2; Substance P; Toluene 2,4-Diisocyanate; Trachea | 1996 |
[Pharmacological profiles of a novel tachykinin NK-2 receptor antagonist, TAC-363].
Topics: Animals; Bronchoconstriction; Capsaicin; Cricetinae; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neurokinin A; Oligopeptides; Receptors, Tachykinin | 1996 |
[Effect of a novel tachykinin NK-2-receptor antagonist, TAC-363, on bronchoconstriction and airway hyperresponsiveness in guinea pigs].
Topics: Animals; Bronchoconstriction; Capsaicin; Citric Acid; Guinea Pigs; Hyperventilation; Male; Neurokinin A; Oligopeptides; Receptors, Tachykinin; Respiratory Hypersensitivity; Tachykinins | 1997 |
Localization of leukaemia inhibitory factor to airway epithelium and its amplification of contractile responses to tachykinins.
Topics: Animals; Capsaicin; Carbachol; Epithelium; Female; Growth Inhibitors; Guinea Pigs; Humans; Immunohistochemistry; In Vitro Techniques; Interleukin-6; Isoproterenol; Leukemia Inhibitory Factor; Lymphokines; Muscle Contraction; Neurokinin A; Substance P; Trachea | 1997 |
Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Ileum; In Vitro Techniques; Neurokinin A; Perfusion; Phentolamine; Substance P; Swine; Tachykinins | 1997 |
Pre- and postjunctional inhibitory effects of fenspiride on guinea-pig bronchi.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Nerve Fibers; Neurokinin A; Neuropeptides; Peptide Fragments; Propranolol; Spiro Compounds; Substance P | 1997 |
PAMP is a novel inhibitor of the tachykinin release in the airway of guinea pigs.
Topics: Adrenomedullin; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Capsaicin; Guinea Pigs; Isoproterenol; Male; Neurokinin A; Peptide Fragments; Peptides; Proteins; Substance P | 1997 |
Tachykinin antagonist FK224 inhibits neurokinin A-, substance P- and capsaicin-induced human bronchial contraction.
Topics: Acetylcholine; Adult; Aged; Bronchi; Capsaicin; Glycopeptides; Histamine; Humans; In Vitro Techniques; Leukotriene D4; Middle Aged; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Protease Inhibitors; Receptors, Tachykinin; Substance P; Tachykinins | 1997 |
Capsaicin and neurokinin A-induced bronchoconstriction in the anaesthetised guinea-pig: evidence for a direct action of menthol on isolated bronchial smooth muscle.
Topics: Airway Resistance; Anesthesia; Animals; Bronchi; Bronchoconstriction; Calcium; Capsaicin; Guinea Pigs; In Vitro Techniques; Male; Menthol; Muscle, Smooth; Neurokinin A | 1997 |
Neurokinin A-LI release after antigen challenge in guinea-pig bronchial tubes: influence of histamine and bradykinin.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Ovalbumin; Pyrilamine; Substance P; Trachea | 1997 |
Cellular pathways mediating tachykinin-evoked secretomotor responses in guinea pig ileum.
Topics: Animals; Capsaicin; Electric Stimulation; Evoked Potentials; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Membrane Potentials; Muscle, Smooth; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tachykinins | 1997 |
Effects of tachykinins and capsaicin on the mechanical and electrical activity of the guinea-pig isolated trachea.
Topics: Animals; Benzamides; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Potassium Channel Blockers; Quinuclidines; Receptors, Neurokinin-2; Substance P; Tachykinins; Tetraethylammonium; Trachea | 1997 |
Role of 5-hydroxytryptamine and mast cells in the tachykinin-induced contraction of rat trachea in vitro.
Topics: Animals; Bronchoconstriction; Capsaicin; In Vitro Techniques; Male; Mast Cells; Neurokinin A; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Serotonin; Substance P; Tachykinins; Trachea | 1997 |
Tachykinins may mediate capsaicin-induced, but not vagally induced motility in porcine antrum.
Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Pyloric Antrum; Receptors, Neurokinin-2; Substance P; Swine; Tachykinins; Vagus Nerve | 1997 |
Selective blockade of substance P or neurokinin A receptors reduces the expression of c-fos in trigeminal subnucleus caudalis after corneal stimulation in the rat.
Topics: Adrenocorticotropic Hormone; Animals; Autonomic Nervous System; Capsaicin; Cornea; Hormones; Immunohistochemistry; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Trigeminal Nucleus, Spinal | 1998 |
Effects of endotracheal intubation on airway neuropeptide content, arterial oxygenation and lung volumes in anaesthetized rats.
Topics: Anesthesia, General; Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Intubation, Intratracheal; Lung Volume Measurements; Neurokinin A; Neuropeptides; Oxygen; Pulmonary Gas Exchange; Rats; Rats, Sprague-Dawley; Respiratory System; Substance P; Vasoactive Intestinal Peptide | 1998 |
Involvement of tachykinin NK1 receptors in plasma protein extravasation induced by tachykinins in the guinea pig upper airways.
Topics: Animals; Antigens; Blood Proteins; Capsaicin; Dextrans; Dipeptides; Extravasation of Diagnostic and Therapeutic Materials; Fluorescein-5-isothiocyanate; Glycopeptides; Guinea Pigs; Indoles; Male; Nasal Mucosa; Neurokinin A; Neurokinin-1 Receptor Antagonists; Olfactory Receptor Neurons; Peptide Fragments; Peptides, Cyclic; Protease Inhibitors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Rhinitis; Substance P | 1997 |
Activation of non-adrenergic non-cholinergic inhibitory pathways by endogenous and exogenous tachykinins in the ferret lower oesophageal sphincter.
Topics: Animals; Capsaicin; Electric Stimulation; Esophagogastric Junction; Female; Ferrets; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Neurokinin A; Neurokinin-1 Receptor Antagonists; Nitroarginine; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Substance P; Tachykinins; Tetrodotoxin | 1998 |
Characterization of the antibronchoconstrictor activity of MEN 11420, a tachykinin NK2 receptor antagonist, in guinea-pigs.
Topics: Amino Acid Sequence; Animals; Atropine; Benzamides; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-2 | 1998 |
Acute and chronic effects of capsaicin in perfused rat muscle: the role of tachykinins and calcitonin gene-related peptide.
Topics: Animals; Benzamides; Calcitonin Gene-Related Peptide; Capsaicin; Male; Muscle, Skeletal; Neurokinin A; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Substance P | 1998 |
Effect of sensory neuropeptides on mucus secretion from cultured goblet cells.
Topics: Animals; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Exocytosis; Guinea Pigs; Male; Mucus; Neurokinin A; Neurokinin B; Substance P; Trachea | 1998 |
Subthreshold concentration of endothelin-1-enhanced, capsaicin-induced bronchoconstriction in anaesthetized guinea-pigs.
Topics: Aerosols; Airway Resistance; Anesthesia; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Guinea Pigs; Male; Neurokinin A; Oligopeptides; Peptides, Cyclic; Piperidines; Substance P | 1998 |
Hyperosmolar saline induces airway resistance changes and neuropeptide release: a comparison with the effect of capsaicin, potassium and histamine.
Topics: Airway Resistance; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Histamine; Neurokinin A; Nitric Oxide; Potassium; Saline Solution, Hypertonic | 1999 |
Naloxone blocks endomorphin-1 but not endomorphin-2 induced inhibition of tachykinergic contractions of guinea-pig isolated bronchus.
Topics: Analgesics, Opioid; Animals; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin A; Oligopeptides; Receptors, Opioid, mu; Tachykinins | 1999 |
Tachykinins stimulate acid and pepsinogen secretion in the isolated porcine stomach.
Topics: Animals; Capsaicin; Electric Stimulation; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Neurokinin A; Pepsinogen A; Radioimmunoassay; Substance P; Swine; Tachykinins; Vagus Nerve | 1999 |
Decreased neuropeptide release may play a role in the pathogenesis of nasal polyps.
Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Capsaicin; Female; Humans; Male; Middle Aged; Nasal Mucosa; Nasal Polyps; Neurokinin A; Neuropeptides; Nose Neoplasms; Prospective Studies; Reference Values; Respiratory Hypersensitivity; Substance P | 1999 |
Effects of nerve stimulation on spontaneously active preparations of the guinea pig ureter.
Topics: Action Potentials; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Electrophysiology; Guinea Pigs; Humans; In Vitro Techniques; Motor Activity; Nervous System Physiological Phenomena; Neurokinin A; Peptides, Cyclic; Substance P; Tachykinins; Thiorphan; Ureter; Urinary Tract Physiological Phenomena | 1999 |
Airway hyperresponsiveness induced by chronic exposure to cigarette smoke in guinea pigs: role of tachykinins.
Topics: Acetylcholine; Air Pressure; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neurokinin A; Neuropeptides; Nicotiana; Piperidines; Plants, Toxic; Receptors, Neurokinin-2; Smoke; Tachykinins; Vagotomy | 1999 |
Modulation of sympathetic nerve activity by perivascular sensory nerves in the arterioles of the guinea-pig small intestine.
Topics: Adenosine Triphosphate; Animals; Arterioles; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Membrane Potentials; Neurokinin A; Neurons, Afferent; Substance P; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction | 1999 |
Respiratory actions of tachykinins in the nucleus of the solitary tract: effect of neonatal capsaicin pretreatment.
Topics: Animals; Animals, Newborn; Capsaicin; Male; Microinjections; Neurokinin A; Neurokinin B; Peptide Fragments; Rats; Rats, Wistar; Respiratory Mechanics; Solitary Nucleus; Substance P; Tachykinins | 2000 |
Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors.
Topics: Animals; Capsaicin; Electric Stimulation; Glucagon; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Nerve Fibers; Neurokinin A; Pancreas; Receptors, Neurokinin-1; Somatostatin; Substance P; Swine; Tachykinins; Vagus Nerve | 2000 |
Tachykinin NK(2) receptors facilitate acetylcholine release from guinea-pig isolated trachea.
Topics: Acetylcholine; Animals; Benzamides; Capsaicin; Choline; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurokinin A; Neurons; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Trachea | 2000 |
Endogenous tachykinins cause bradycardia by stimulating cholinergic neurons in the isolated guinea pig heart.
Topics: Acetylcholine; Animals; Atropine; Bradycardia; Calcitonin Gene-Related Peptide; Capsaicin; Cholinergic Fibers; Ganglia, Autonomic; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscle Fibers, Skeletal; Myocardium; Neostigmine; Neurokinin A; Neurons, Afferent; Parasympatholytics; Parasympathomimetics; Peptide Fragments; Vasodilator Agents | 2000 |
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs.
Topics: Administration, Inhalation; Airway Resistance; Animals; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Guinea Pigs; Histamine; Leukocyte Count; Lung; Male; Methacholine Chloride; Neurokinin A; Ovalbumin; Peptide Fragments; Smoking; Substance P; Wakefulness | 2001 |
Potent NK1 antagonism by SR-140333 reduces rat colonic secretory response to immunocyte activation.
Topics: Animals; Benzamides; Capsaicin; Colon; Colonic Diseases, Functional; Electric Stimulation; Male; Mast Cells; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Stress, Physiological; Substance P | 2001 |
Involvement of spinal NK2 and NMDA receptors in aversive behavior induced by intra-arterial injection of capsaicin.
Topics: Animals; Avoidance Learning; Biphenyl Compounds; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Femoral Artery; Guinea Pigs; Hindlimb; Injections, Intra-Arterial; Male; Neurokinin A; Nociceptors; Pain; Peptide Fragments; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Spinal Cord; Vocalization, Animal | 2001 |
Capsaicin pre- and post-treatment on rat monocrotaline pneumotoxicity.
Topics: Animals; Capsaicin; Functional Residual Capacity; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Neprilysin; Neurokinin A; Organ Size; Rats; Rats, Sprague-Dawley; Substance P; Total Lung Capacity | 2000 |
Developmental expression of neurokinin A and functional neurokinin-2 receptors in lung.
Topics: Adult; Barium Compounds; Bronchoconstriction; Bronchoconstrictor Agents; Capsaicin; Chlorides; Fetus; Gene Expression Regulation, Developmental; Humans; Immunohistochemistry; In Vitro Techniques; Lung; Methacholine Chloride; Muscle, Smooth; Neurokinin A; Peptides; Perfusion; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trachea | 2001 |
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Capsaicin; Diclofenac; Duodenum; Gastric Mucins; Male; Misoprostol; Neurokinin A; Oligopeptides; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptor, PAR-2; Receptors, Thrombin; Saliva; Stomach; Substance P | 2001 |
An animal model to assess aversion to intra-oral capsaicin: increased threshold in mice lacking substance p.
Topics: Administration, Oral; Animals; Capsaicin; Drug Tolerance; Irritants; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Neurokinin A; Protein Precursors; Species Specificity; Substance P; Tachykinins; Taste Threshold | 2001 |
Human colonic anti-secretory activity of the potent NK(1) antagonist, SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease.
Topics: Animals; Antidiarrheals; Capsaicin; Colitis, Ulcerative; Colon; Crohn Disease; Epithelial Cells; Food Hypersensitivity; Guinea Pigs; Humans; Immunoglobulin E; Inflammatory Bowel Diseases; Male; Mast Cells; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Receptors, Neurokinin-1; Species Specificity; Substance P; Tachykinins | 2001 |
The role of sensory neuropeptides in motor innervation of the hamster isolated urinary bladder.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cricetinae; Drug Interactions; Electric Stimulation; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth; Neurokinin A; Urinary Bladder | 2001 |
Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blepharitis; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Cells, Cultured; Drug Synergism; Female; Ganglia, Spinal; Guinea Pigs; Inflammation; Lectins; Male; Neurokinin A; Neurons; Plant Extracts; Plant Lectins; Rats; Ricinoleic Acids; Seeds; Substance P | 2001 |
Pronociceptive effects of nociceptin/orphanin FQ (13-17) at peripheral and spinal level in mice.
Topics: Animals; Baculoviridae; Capsaicin; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Spinal; Male; Mice; Mutation; Neurokinin A; Nociceptors; Opioid Peptides; Peptide Fragments; Peripheral Nerves; Recombinant Proteins; Spinal Cord; Virulence Factors, Bordetella | 2001 |
Nitric oxide is generated in smooth muscle layer by neurokinin A and counteracts constriction in guinea pig airway.
Topics: Airway Resistance; Animals; Benzamides; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Piperidines; Receptors, Neurokinin-2; Trachea | 2001 |
The neurosensory tachykinins substance P and neurokinin A directly induce keratinocyte nerve growth factor.
Topics: Animals; Capsaicin; Cell Line, Transformed; Epidermis; Female; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Nerve Growth Factor; Neurokinin A; Neuropeptides; RNA, Messenger; Substance P; Up-Regulation | 2001 |
Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction.
Topics: Animals; Benzamides; Bradykinin; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Glycopeptides; Guinea Pigs; Indoles; Lung; Male; Metalloendopeptidases; Neurokinin A; Piperidines; Substance P | 2001 |
Cyclo-oxygenase- and capsaicin-sensitive afferent fibres affect Beta-adrenoceptor-evoked response in the rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Indomethacin; Isoproterenol; Male; Muscle, Smooth; Neurokinin A; Papaverine; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Ruthenium Red; Urinary Bladder; Visceral Afferents | 2002 |
Role of tachykinins in sephadex-induced airway hyperreactivity and inflammation in guinea pigs.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cell Count; Cyclohexylamines; Dextrans; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Indoles; Inflammation; Macrophages; Male; Neurokinin A; Peptides, Cyclic; Receptors, Tachykinin; Substance P; Tachykinins; Time Factors; Vasodilator Agents | 2002 |
Tachykinin-independent activity of capsaicin on in-vitro lamb detrusor.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Male; Muscle Relaxation; Neurokinin A; Neurons, Afferent; Sheep; Tachykinins; Urinary Bladder | 2002 |
Bone marrow transplantation reveals an essential synergy between neuronal and hemopoietic cell neurokinin production in pulmonary inflammation.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Capsaicin; Enzyme-Linked Immunosorbent Assay; Gene Deletion; Gene Expression Regulation; Hematopoietic Stem Cells; Immune System; Inflammation; Ligands; Lung; Mice; Mice, Transgenic; Neurokinin A; Neurons; Protein Precursors; Respiration; Substance P; Tachykinins; Time Factors; Trachea | 2003 |
A role for tachykinins in female mouse and rat reproductive function.
Topics: Animals; Capsaicin; Embryo, Mammalian; Female; Fertility; Gene Expression Regulation; Litter Size; Male; Mice; Neprilysin; Neurokinin A; Neurokinin B; Oocytes; Ovary; Pregnancy; Protein Precursors; Rats; Rats, Wistar; Receptors, Tachykinin; RNA, Messenger; Spermatozoa; Substance P; Tachykinins; Uterus | 2003 |
PAR-2 agonists induce contraction of murine small intestine through neurokinin receptors.
Topics: Animals; Benzamides; Capsaicin; Female; Intestine, Small; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Oligopeptides; Piperidines; Quinuclidines; Receptor, PAR-2; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Tetrodotoxin; Trypsin | 2003 |
Tachykinin receptor (NK(1), NK(2), NK(3)) binding sites in the rat caudal brainstem following neonatal capsaicin administration.
Topics: Animals; Animals, Newborn; Autoradiography; Brain Stem; Capsaicin; Indicators and Reagents; Iodine Radioisotopes; Neurokinin A; Peptide Fragments; Rats; Receptors, Tachykinin; Substance P; Succinimides | 2003 |
Biologic activity of the tachykinins on lamb and sheep gallbladder.
Topics: Animals; Binding Sites; Capsaicin; Dose-Response Relationship, Drug; Female; Gallbladder; Male; Muscles; Neurokinin A; Neurokinin B; Peptide Fragments; Physalaemin; Protein Structure, Tertiary; Pyrrolidonecarboxylic Acid; Receptors, Tachykinin; Sheep; Substance P; Tachykinins | 2003 |
Effects of neuropeptides on the sumatriptan-disturbed circulation in the optic nerve head of rabbits.
Topics: Animals; Arterioles; Blood-Retinal Barrier; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Male; Microinjections; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neuropeptides; Optic Nerve; Peptide Fragments; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Retinal Vessels; Substance P; Sumatriptan; Vasodilation | 2004 |
Influence of maturation on constrictive response to stimulation of C-fiber afferents in isolated guinea pig airways.
Topics: Aging; Animals; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Nerve Fibers, Unmyelinated; Neurokinin A; Neurons, Afferent; Osmolar Concentration; Radioimmunoassay; Stimulation, Chemical; Substance P; Trachea; Vasoconstriction | 2004 |
Role of neuropeptide receptor systems in vanilloid VR1 receptor-mediated gastric acid secretion in rat brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Excitatory Amino Acid Antagonists; Gastric Acid; Hypothalamus; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Quinuclidines; Rats; Rats, Wistar; Receptor Cross-Talk; Receptors, Calcitonin Gene-Related Peptide; Receptors, Drug; Receptors, Glutamate; Receptors, Neurokinin-2; Time Factors; TRPV Cation Channels | 2004 |
Effects of TAK-637 on NK(1) receptor-mediated mechanisms regulating colonic secretion.
Topics: Animals; Capsaicin; Colforsin; Colon; Electric Stimulation; Electrophysiology; Guinea Pigs; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Male; Naphthyridines; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Receptors, Neurokinin-1; Statistics, Nonparametric; Substance P; Tetrodotoxin | 2004 |
Greater involvement of neurokinins found in Guinea pig models of severe asthma compared with mild asthma.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Disease Models, Animal; Eosinophils; Guinea Pigs; Lung; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Respiratory Hypersensitivity; Severity of Illness Index; Substance P | 2004 |
Neurokinins and inflammatory cell iNOS expression in guinea pigs with chronic allergic airway inflammation.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Bronchial Hyperreactivity; Capsaicin; Chronic Disease; Elasticity; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Inflammation; Lung; Male; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovalbumin | 2005 |
Neurokinin a is a main constituent of sensory neurons innervating the anterior segment of the eye.
Topics: Aged; Aged, 80 and over; Animals; Animals, Newborn; Anterior Eye Segment; Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; Female; Fluorescent Antibody Technique, Indirect; Humans; In Situ Hybridization; Male; Middle Aged; Neurokinin A; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Tachykinins; Trigeminal Ganglion | 2005 |
GABA(A) receptor facilitation of neurokinin release from primary afferent terminals in the rat spinal cord.
Topics: Action Potentials; Animals; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Endocytosis; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Nerve Fibers, Unmyelinated; Neurokinin A; Neurons, Afferent; Nociceptors; Organ Culture Techniques; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Neurokinin-1; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 2005 |
Pharmacological investigation of hydrogen sulfide (H2S) contractile activity in rat detrusor muscle.
Topics: Animals; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Hydrogen Sulfide; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; omega-Conotoxin GVIA; Rats; Rats, Wistar; Ruthenium Red; Sulfides; Urinary Bladder | 2005 |
Impaired capsaicin and neurokinin-evoked colonic motility in inflammatory bowel disease.
Topics: Adult; Aged; Aged, 80 and over; Capsaicin; Case-Control Studies; Colon; Electric Stimulation; Gastrointestinal Motility; Humans; Inflammatory Bowel Diseases; Middle Aged; Neurokinin A; Neuromuscular Junction; Peptide Fragments; Stimulation, Chemical; Synaptic Transmission; Tissue Culture Techniques | 2005 |
Neurokinins enhance excitability in capsaicin-responsive DRG neurons.
Topics: Action Potentials; Animals; Capsaicin; Electric Stimulation; Enzyme Activation; Ganglia, Spinal; Intracellular Membranes; Male; Neurokinin A; Neurons, Afferent; Patch-Clamp Techniques; Peptide Fragments; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptors, Neurokinin-2; Signal Transduction; Substance P; Tachykinins | 2007 |
Intraluminal acid induces oesophageal shortening via capsaicin-sensitive neurokinin neurons.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Esophagus; Female; Gastric Acid; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Opossums; Peptide Fragments; Receptors, Neurokinin-2; Substance P; Tissue Culture Techniques | 2007 |
Capsaicin-sensitive nerves and neurokinins modulate non-neuronal nNOS expression in lung.
Topics: Airway Resistance; Algorithms; Animals; Capsaicin; Eosinophils; Epithelial Cells; Guinea Pigs; Immunohistochemistry; Lung; Male; Monocytes; Neurokinin A; Neurons; Nitric Oxide Synthase Type I; Respiratory Mechanics; Respiratory Mucosa | 2008 |
Pelviureteric peristaltic contractions in diabetic rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Humans; In Vitro Techniques; Kidney Pelvis; Male; Matched-Pair Analysis; Muscle Contraction; Muscle Strength; Muscle, Smooth; Neurokinin A; Neurotransmitter Agents; Peristalsis; Rats; Rats, Wistar; Sensory System Agents; Substance P; Ureter | 2007 |
Novel triple neurokinin receptor antagonist CS-003 strongly inhibits neurokinin related responses.
Topics: Animals; Bronchi; Capillary Permeability; Capsaicin; Chlorocebus aethiops; Citric Acid; COS Cells; Cough; Cyclic S-Oxides; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Inositol Phosphates; Male; Molecular Sequence Data; Morpholines; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Trachea | 2008 |
Neurokinin 2 receptor-mediated activation of protein kinase C modulates capsaicin responses in DRG neurons from adult rats.
Topics: Age Factors; Animals; Calcium; Capsaicin; Carcinogens; Cells, Cultured; Ganglia, Spinal; Male; Neurokinin A; Neurokinin B; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Peptide Fragments; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Sensory System Agents; Signal Transduction; Substance P; TRPV Cation Channels | 2008 |
Morphine-induced early delays in wound closure: involvement of sensory neuropeptides and modification of neurokinin receptor expression.
Topics: Animals; Capsaicin; Gene Expression Regulation; Male; Morphine; Neurokinin A; Neuropeptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Wound Healing; Wounds and Injuries | 2009 |
Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon.
Topics: Animals; Atropine; Capsaicin; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Immunohistochemistry; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurokinin A; Pyrazines; Pyridines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Rectum; Substance P; Tetrodotoxin; Time Factors; TRPV Cation Channels; Ubiquitin Thiolesterase | 2009 |
Proteinase-activated receptor-2 activation evokes oesophageal longitudinal smooth muscle contraction via a capsaicin-sensitive and neurokinin-2 receptor-dependent pathway.
Topics: Animals; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Esophagus; Female; Immunohistochemistry; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Opossums; Peptide Fragments; Receptor, PAR-2; Receptors, Neurokinin-2; Signal Transduction; Substance P; Trypsin | 2010 |
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia.
Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Disease Models, Animal; Formaldehyde; Glycyrrhetinic Acid; Hot Temperature; Humans; Hyperalgesia; Inflammation; Ligation; Male; Neuralgia; Neurokinin A; Neurokinin B; Pain; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Sciatic Nerve; Substance P | 2011 |
Contribution of sensory nerves to LPS-induced hyperresponsiveness of human isolated bronchi.
Topics: Anilides; Bronchi; Bronchial Hyperreactivity; Capsaicin; Cinnamates; Electric Stimulation; Female; Humans; Indoles; Lipopolysaccharides; Male; Middle Aged; Muscle Contraction; Neprilysin; Neurokinin A; Piperidines; Sensory Receptor Cells; TRPV Cation Channels; Up-Regulation | 2015 |
Ureteral relaxation through calcitonin gene-related peptide release from sensory nerve terminals by hypotonic solution.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Hypotonic Solutions; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Neurotransmitter Agents; Osmolar Concentration; Peptide Fragments; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Tissue Culture Techniques; TRPV Cation Channels; Ureter; Urinalysis | 2015 |
The research of the possible mechanism and the treatment for capsaicin-induced cough.
Topics: Animals; Antitussive Agents; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Codeine; Cough; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Guinea Pigs; Male; Neurokinin A; Pyrrolidines; Substance P; TRPV Cation Channels; Urea | 2018 |
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.
Topics: Administration, Inhalation; Age Factors; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Neurokinin A; Neurokinin B; Rats; Rats, Sprague-Dawley; Respiration; Sevoflurane; Substance P; Trachea; TRPV Cation Channels | 2020 |
TRPM3 channel activation inhibits contraction of the isolated human ureter via CGRP released from sensory nerves.
Topics: Adult; Aged; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Middle Aged; Muscle Contraction; Nephrectomy; Neurokinin A; Organ Culture Techniques; Pregnenolone; Primidone; Sensory Receptor Cells; TRPM Cation Channels; Ureter | 2021 |
Inflammatory and contractile profile in LPS-challenged equine isolated bronchi: Evidence for IL-6 as a potential target against AHR in equine asthma.
Topics: Animals; Asthma; Bronchi; Capsaicin; Horses; Inflammation; Interleukin-33; Interleukin-6; Lipopolysaccharides; Neurokinin A; Transforming Growth Factor beta | 2022 |