capsaicin has been researched along with indomethacin in 234 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (9.83) | 18.7374 |
| 1990's | 105 (44.87) | 18.2507 |
| 2000's | 76 (32.48) | 29.6817 |
| 2010's | 29 (12.39) | 24.3611 |
| 2020's | 1 (0.43) | 2.80 |
| Authors | Studies |
|---|---|
| Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Chen, Z; He, GJ; Li, XG; Mou, X; Ye, XL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Cao, Z; Hammock, BD; Hwang, SH; Lee, KS; Li, X; Morisseau, C; Wagner, K; Xu, J; Yang, J | 1 |
| Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Sakamoto, S | 1 |
| Brzozowski, T; Drozdowicz, D; Konturek, SJ; Majka, J | 1 |
| Altiere, RJ; Diamond, L; Thompson, DC | 1 |
| Del Bianco, E; Geppetti, P; Maggi, CA; Santicioli, P; Tramontana, M | 1 |
| Del Bianco, E; Giuliani, S; Maggi, CA; Santicioli, P | 1 |
| Giuliani, S; Maggi, CA; Santicioli, P; Theodorsson, E | 1 |
| Håkanson, R; Wallengren, J | 1 |
| Rechtman, MP | 1 |
| Manzini, S | 1 |
| Matsumoto, J; Okabe, S; Tachibana, K; Takeuchi, K; Ueshima, K | 1 |
| Matsumoto, J; Ohuchi, T; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Matsumoto, J; Okabe, S; Takeuchi, K; Ueshima, K | 2 |
| Tepperman, BL; Whittle, BJ | 1 |
| Moritoki, H; Takase, H; Tanioka, A | 1 |
| Andersson, RG; Grundemar, L; Grundström, N; Håkanson, R; Johansson, IG | 1 |
| Chitano, P; Fabbri, LM; Maggi, CA; Mapp, CE; Patacchini, R | 1 |
| Matsumoto, J; Niida, H; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Del Bianco, E; Geppetti, P; Maggi, CA; Patacchini, R; Santicioli, P; Tramontana, M | 1 |
| Benedito, S; Nyborg, NC; Prieto, D | 1 |
| McEvoy, RD; Reynolds, AM; Scicchitano, R; Zadow, SP | 1 |
| Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF | 1 |
| Dickenson, A; Dray, A | 1 |
| Esplugues, JV; Whittle, BJ | 1 |
| Lopez-Belmonte, J; Whittle, BJ | 1 |
| Karlsson, JA; Lundberg, JM; Zackrisson, C | 1 |
| Manzini, S; Meini, S | 1 |
| Deshpande, YG; Fitzgerald, S; Kaminski, DL; Nguyen, HQ | 1 |
| Evangelista, S; Pfeiffer, CJ | 1 |
| Krell, RD; McCarthy, M | 1 |
| Guth, PH; Holzer, P; Yonei, Y | 1 |
| Miller, IF; Wong, LB; Yeates, DB | 1 |
| De Luca, A; Rand, MJ | 1 |
| Uchida, M; Watanabe, K; Yano, S | 1 |
| Ellis, JL; Undem, BJ | 1 |
| Lopez-Belmonte, J; Moncada, S; Whittle, BJ | 1 |
| Diener, M; Rummel, W | 1 |
| Barnes, PJ; Belvisi, MG; Ichinose, M | 1 |
| Wali, FA | 1 |
| Abelli, L; Giuliani, S; Maggi, CA; Meli, A; Regoli, D; Santicioli, P | 1 |
| Barnes, PJ; Frossard, N; Rhoden, KJ | 1 |
| Drazen, JM; Shore, SA | 1 |
| Inoki, R; Ohkubo, T; Shibata, M; Takahashi, H | 1 |
| Cecconi, R; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P | 1 |
| Franco-Cereceda, A | 1 |
| Lahti, A; Maibach, HI; McDonald, DM; Tammi, R | 1 |
| Conte, B; Furio, M; Giuliani, S; Gragnani, L; Maggi, CA; Meli, A; Meli, P; Santicioli, P | 1 |
| Evangelista, S; Giuliani, S; Maggi, CA; Meli, A | 1 |
| Dray, A; Forster, PL; Perkins, MN | 1 |
| Holzer, P; Sametz, W | 1 |
| Borsini, F; Giuliani, S; Maggi, CA; Meli, A; Santicioli, P | 1 |
| Ordway, GA; Waldrop, TG | 1 |
| Evangelista, S; Maggi, CA; Meli, A | 2 |
| DiBona, GF; Holdaas, H; Kopp, UC | 1 |
| Hsu, MF; Hsu, TP; Teng, CM; Wang, JP | 1 |
| Fennessy, MR; Stewart, AG; Thompson, DC | 1 |
| Belis, JA; Galie, JR; Longhurst, PA; O'Donnell, JP; Westfall, DP | 1 |
| Bito, LZ; Camras, CB | 1 |
| Bill, A; Mandahl, A | 1 |
| Donnerer, J; Gamillscheg, A; Holzer, P; Lembeck, F | 1 |
| Chole, RA; Sherman, BE | 1 |
| Bolser, DC; Chapman, RW; DeGennaro, FC; Hey, JA; O'Reilly, S | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Advenier, C; Hirsch, A; Martin, CA; Molimard, M; Naline, E | 2 |
| Davison, JS; Mathison, R | 1 |
| Cho, CH; Ko, JK; Tang, XL | 1 |
| Brain, SD; Newbold, P | 1 |
| Giuliani, S; Lecci, A; Maggi, CA; Meini, S | 1 |
| Kinoshita, M; Kume, E; Tamaki, H | 1 |
| Advenier, C; Molimard, M | 1 |
| Kopp, UC; Smith, LA | 1 |
| Eljamal, M; Wong, LB; Yeates, DB | 1 |
| Back, SM; Hua, XY; Jinno, S; Tam, EK; Yaksh, TL | 1 |
| Chiba, T; Inui, T; Kinoshita, Y | 1 |
| Duckles, SP; Li, YJ | 1 |
| Herbert, MK; Holzer, P | 1 |
| Narita, M; Ohuchi, T; Okabe, S; Takeuchi, K | 1 |
| Schultz, HD; Ustinova, EE | 2 |
| Franco-Cereceda, A; Källner, G; Lundberg, JM | 1 |
| Hollenberg, MD; Muramatsu, I | 1 |
| Arbetter, K; Leff, AR; Mitchell, RW; Ndukwu, IM; Solway, J | 1 |
| Saperas, E; Taché, Y | 1 |
| Matsumoto, J; Ohuchi, T; Okabe, S; Takeuchi, K | 1 |
| Bunnett, NW; Debas, HT; Gray, JL; Mulvihill, SJ; Orloff, SL | 1 |
| Dempsey, DT; Mercer, DW; Ritchie, WP | 1 |
| Herbert, MK; Schmidt, RF; Tafler, R; Weis, KH | 1 |
| Brain, SD; Cambridge, H | 1 |
| Burchert, M; Lambrecht, N; Müller, KM; Peskar, BM; Respondek, M | 1 |
| Larkin, SW; Williams, TJ | 1 |
| Brzozowski, T; Drozdowicz, D; Konturek, SJ; Majka, J; Pytko-Polonczyk, J; Szlachcic, A | 1 |
| Barrachina, D; Calatayud, S; Esplugues, JV; Martínez-Cuesta, A; Moreno, L; Whittle, BJ | 1 |
| Gao, XP; Jaffe, HA; Olopade, CO; Rubinstein, I | 1 |
| Bando, T; Fujimura, M; Hashimoto, T; Kamio, Y; Kasahara, K; Matsuda, T | 1 |
| Back, SM; Hua, XY; Tam, EK | 1 |
| Artuković, B; Bratulić, M; Buljat, G; Gjurasin, M; Grabarević, Z; Jagić, V; Jurina, L; Konjevoda, P; Ljubanović, D; Marović, A; Miklić, P; Mise, S; Petek, M; Rotkvić, I; Rucman, R; Seiwerth, S; Separović, J; Sikirić, P; Tisljar, M; Turković, B; Zoricić, I | 1 |
| Hatakeyama, Y; Ohtsuka, M; Shimomura, K; Tomoi, M | 1 |
| Hua, XY; Jinno, S; Wong, S; Yaksh, TL | 1 |
| Wang, W; Zucker, IH | 1 |
| Brzozowski, T; Ernst, H; Hahn, EG; Konturek, PC; Konturek, SJ; Sliwowski, K | 1 |
| Hirata, T; Kato, S; Takeuchi, K | 1 |
| Advenier, C; Crambes, O; Girard, V; Lundberg, JM; Malbezin, M; Malmström, RE; Naline, E | 1 |
| Abdel Salam, OM; Mózsik, G; Szolcsányi, J | 1 |
| Denee, JH; Muis, T; Nijkamp, FP; Rivas, TO; van Heuven-Nolsen, D; Westra-De Vlieger, JF | 1 |
| Angel, F; Chevalier, E; Dahl, SG; Diop, L; Friese, N; Rivière, PJ | 1 |
| Brzozowski, T; Drozdowicz, D; Kedra, D; Konturek, SJ; Sliwowski, Z; Zaczek, M | 1 |
| Guth, PH; Király, A; Sütó, G; Taché, Y | 1 |
| Schultz, HD; Ustinova, EE; Wang, W; Zucker, IH | 1 |
| Desouza, IA; Ribeiro-DaSilva, G | 1 |
| Joseph, SA; Nappi, G; Tassorelli, C | 1 |
| Hashimoto, M; Takagi, H; Yamamoto, Y | 1 |
| Arner, A; Grampp, W; Skogvall, S | 1 |
| Goswami, S; Maayani, S; Rienzi, N; Schachter, EN; Zuskin, E | 1 |
| Kaneko, H; Kaunitz, J; Taché, Y | 1 |
| Atwood, L; James, C; Morris, GP; Vanner, S | 1 |
| Castaneda, AA; Cross, JM; Gunter, JA; Mercer, DW | 1 |
| Mustafa, SM; Oriowo, MA; Pilcher, CW; Williams, KI | 1 |
| Kang, JY; Tu, Y | 1 |
| Grampp, W; Skogvall, S | 1 |
| Buckingham, JC; Kennard, C; Rhodes, KF | 1 |
| Li, Y; Matsuda, H; Yoshikawa, M | 2 |
| Aoyama, M; Arai, Y; Inaba, N; Lee, B; Onodera, S; Shibata, M; Tanaka, M; Yamaura, T | 1 |
| Ma, R; Schultz, HD; Wang, W | 1 |
| Aoyama, M; Arai, Y; Inaba, N; Nishizawa, A; Onodera, S; Sekine, Y; Shibata, M; Suzuki, T; Tanaka, M | 1 |
| Cocks, TM; Moffatt, JD | 1 |
| Kato, S; Kunikata, T; Takeuchi, K; Tanaka, A; Umeda, M | 1 |
| Flemström, G; Hellgren, S; Nylander, O | 1 |
| Guidobono, F; Netti, C; Pagani, F; Rapetti, D; Sibilia, V; Soglian, A | 1 |
| Chen, HY; Fang, CL; Fang, JY; Hong, CT; Lin, TY; Wei, HM | 1 |
| Ralevic, V | 1 |
| Fisher, JT; Marantz, MJ; Vincent, SG | 1 |
| Boschetto, P; Chitano, P; De Marzo, N; Fabbri, LM; Faggian, D; Jovine, L; Mapp, CE; Plebani, M | 1 |
| Desouza, IA; Franco-Penteado, CF; Hyslop, S; Ribeiro-DaSilva, G | 2 |
| Craib, SJ; Ellington, HC; Pertwee, RG; Ross, RA | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Ptak, A; Sliwowski, Z | 1 |
| Bottrill, FE; Ford, WR; Hiley, CR; Ho, WS; White, R | 1 |
| Boachie-Ansah, G; Grainger, J | 1 |
| Ikeda, Y; Naraba, H; Oh-ishi, S; Ueno, A | 1 |
| Deng, HW; Li, YJ; Song, QJ; Xiao, J | 1 |
| Isobe, S; Kawasaki, H; Kurosaki, Y; Nakatsuma, A; Nawa, H | 1 |
| Bartocci, C; Bolle, P; Tucci, P | 1 |
| Harris, D; Kendall, DA; McCulloch, AI; Randall, MD | 1 |
| Harada, N; Katsuragi, T; Okajima, K; Uchiba, M | 1 |
| Towheed, TE | 1 |
| Kato, S; Matsumoto, M; Nakashima, M; Ogawa, Y; Takeeda, M; Takeuchi, K | 1 |
| Harty, RF; Mesiya, S; Saymeh, L; Vongthavaravat, V; Xia, Y | 1 |
| Arai, K; Hayashi, I; Kamata, K; Majima, M; Mizuguchi, S; Murata, T; Narumiya, S; Ohno, T; Saeki, T; Saigenji, K | 1 |
| Alexandre-Moreira, MS; Barreiro, EJ; Bolzani, Vda S; Palhares de Miranda, AL; Viegas, C | 1 |
| Hayashi, K; Ishikawa, T; Nakayama, K; Tajima, T; Yamashita, T | 1 |
| Hayashi, Y; Murakami, M; Takeeda, M; Takeuchi, K; Yamato, M | 1 |
| Jenkins, DW; Langmead, CJ; Parsons, AA; Strijbos, PJ | 1 |
| Angel, F; Aunis, D; Crenner, F; Ghia, JE; Metz-Boutigue, MH | 1 |
| Brzozowski, T; Drozdowicz, D; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Pawlik, WW; Sliwowski, Z | 1 |
| Inoue, A; Nakata, Y; Oshita, K; Tang, HB | 1 |
| Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C | 1 |
| Blanco, MM; Freire, AO; Mello, LE; Sugai, GC; Tabosa, A; Yamamura, Y | 1 |
| Harada, N; Isobe, H; Okajima, K; Uchiba, M | 2 |
| Ando, R; Watanabe, C | 1 |
| Abdel-Salam, OM | 1 |
| Mózsik, G; Rácz, I; Szolcsányi, J | 1 |
| Hasegawa, N; Inoi, N; Inoshita, K; Kanke, T; Kawabata, A; Saito, N; Sekiguchi, F; Yonezawa, D | 1 |
| Brzozowska, I; Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pawlik, M; Pawlik, WW; Sliwowski, Z; Zwirska-Korczala, K | 1 |
| Aihara, E; Hayashi, M; Sasaki, Y; Takeuchi, K | 1 |
| Bagaeva, T; Bobryshev, P; Filaretova, L | 1 |
| Aihara, E; Hayashi, M; Kato, S; Nomura, Y; Takeuchi, K | 1 |
| Hiley, CR; Hoi, PM | 1 |
| Bergren, DR | 1 |
| Ay, I; Tuncer, M | 1 |
| Amadesi, S; Andre, E; Bunnett, NW; Dinh, TQ; Fischer, A; Gatti, R; Geppetti, P; Harrison, S; Trevisani, M | 1 |
| Kou, YR; Lin, KS; Lin, YS; Ruan, T | 1 |
| Aoi, Y; Fukushima, K; Kato, S; Takeuchi, K | 1 |
| Berglund, M; Dalence-Guzmán, MF; Jönsson, P; Persson, CG; Skogvall, S; Sterner, O; Svensson, K | 1 |
| Bülbül, M; Izgüt-Uysal, VN; Ongüt, G; Tan, R; Tosun, O | 1 |
| Bobryshev, P; Filaretova, L; Maltcev, N; Podvigina, T | 1 |
| Harada, N; Okajima, K | 1 |
| Bagaeva, TR; Bobryshev, PIu; Filaretova, LP; Podvigina, TT | 1 |
| Baron, R; Binder, A; Hedderich, J; Schattschneider, J; Wasner, G; Zum Buttel, I | 1 |
| Matsuda, H; Nagatomo, A; Ochi, M; Yoshikawa, M | 1 |
| Asano, M; Harada, N; Mishima, A; Nakayama, T; Nomura, N; Okajima, K; Saito, T | 1 |
| Bobryshev, PIu; Filaretova, LP; Levkovich, IuI; Mal'tsev, NA; Podvigina, TT | 1 |
| Bagaeva, T; Bobryshev, P; Filaretova, L; Podvigina, T; Takeuchi, K | 1 |
| Herradón, E; López-Miranda, V; Martín, MI | 1 |
| Cefalu, JS; Cockayne, DA; Eggers, AC; Ford, AP; Ho, MJ; Jett, MF; Kaan, TK; Nunn, PA; Zhu, QM | 1 |
| de Olinda, TM; Lemos, TL; Machado, LL; Rao, VS; Santos, FA | 1 |
| Chancellor, MB; de Groat, WC; Kihara, K; Masuda, H; Matsuoka, Y; Saito, K; Yoshida, S; Yoshimura, N | 1 |
| Brain, SD; Clark, N; Graepel, R; Grant, A; Keeble, J; Schmidhuber, S; Shah, AM; Starr, A | 1 |
| Kato, S; Mashita, Y; Matsuzaka, Y; Takeuchi, K; Taniguchi, M | 1 |
| Palmery, M; Piccolotti, P; Pimpinella, G; Romanelli, L; Tucci, P; Valeri, P | 1 |
| Beckmann, N; Blé, FX; Cannet, C; Fozard, JR; Karmouty-Quintana, H; Page, CP; Zurbruegg, S | 1 |
| Carvalho, AC; de Queiroz, SS; Guedes, MM; Lima, AF; Lira, SR; Rao, VS; Santos, FA; Silveira, ER | 1 |
| Bagaeva, TR; Bobryshev, PIu; Filaretova, LP; Levkovich, IuI; Mal'tsev, NA; Podvigina, TT | 1 |
| Kadoi, Y; Kudo, K; Mizutani, A; Mizutani, S; Murakami, K; Noguchi, T; Okajima, K; Uchino, T | 1 |
| Al-Asmar, B; Chidiac, JJ; Jabbur, SJ; Rifai, K; Saadé, NE | 1 |
| Bastos, LC; Tonussi, CR | 1 |
| Bagaeva, TR; Bobryshev, PY; Filaretova, LP; Levkovich, YI; Mal'tsev, NA; Podvigina, TT | 1 |
| Tanahashi, M; Uchida, W; Yoshioka, K | 1 |
| Aihara, E; Ohashi, Y; Okuda, S; Sasaki, Y; Takahashi, K; Takasuka, H; Takeuchi, K | 1 |
| Albuquerque, RL; de Andrade, GM; de Morais, SM; de Souza, CM; Rao, VS; Rodrigues, Pde A; Santos, FA; Silva, AR; Silva, MG | 1 |
| Bien, MY; Hsu, CC; Hsu, HC; Kou, YR; Lin, YS; Weng, HT | 1 |
| Brzozowski, T; Burnat, G; Konturek, PC; Konturek, SJ; Koziel, J; Ptak-Belowska, A; Sliwowski, Z | 1 |
| Andersson, KE; Gratzke, C; Hedlund, P; Stief, C; Streng, T; Weinhold, P | 1 |
| Aihara, E; Hayashi, S; Ise, F; Koyama, M; Takahashi, K; Takasuka, H; Takeuchi, K | 1 |
| Alexander, SP; Randall, MD; Wheal, AJ | 1 |
| Bai, ZT; Cheng, M; Hua, LM; Ji, YH; Jiang, F; Liu, T; Pang, XY; Shi, J; Shu, XQ; Zhang, JW; Zhou, JJ | 1 |
| Henry, PJ; Mann, TS; Taylor, SJ | 1 |
| Boczán, J; Czikora, Á; Daragó, A; Édes, I; Lizanecz, E; Papp, Z; Tóth, A | 1 |
| Araújo Castro, C; Coelho de Souza, G; de Azevedo Moreira, R; de Oliveira Monteiro-Moreira, AC; de Vasconcellos Abdon, AP; Moreira Guedes, M; Noronha Coelho de Souza, L; Pereira Lima, RC; Prado Vasconcelos, R; Rolim Campos, A | 1 |
| Jin, H; Kawasaki, H; Kitamura, Y; Koyama, T; Sun, P; Takatori, S; Tangsucharit, P; Zamami, Y | 1 |
| Baranowska-Kuczko, M; Kozłowska, H; MacLean, MR; Malinowska, B | 1 |
| Akella, A; Deshpande, SB; Dutta, A | 1 |
| Amagase, K; Satoh, H; Takeuchi, K | 1 |
| Czimmer, J; Mózsik, G; Szabó, IL; Szolcsányi, J | 1 |
| Bartho, L; Benko, R; Dékány, A; Szombati, V | 1 |
| Ho, CY; Kou, YR; Lai, CJ; Liu, BY; Lu, SH; Tsai, TL | 1 |
| Barahona, MV; Bustamante, S; Carballido, J; Fernandes, VS; García-Sacristán, A; Hernández, M; Martínez, AC; Martínez-Sáenz, A; Orensanz, LM; Prieto, D; Recio, P; Ribeiro, AS | 1 |
| Aihara, E; Hayashi, S; Ise, F; Takahashi, K; Takeuchi, K | 1 |
| Camargo, LL; Costa, SK; Denadai-Souza, A; Fernandes, E; Grant, A; Lima, C; Mesquita, FP; Muscará, MN; Schenka, A; Soares, AG; Yshii, LM | 1 |
| Coutinho, HD; de Albuquerque, TR; de Lacerda Neto, LJ; de Menezes, IR; de Oliveira, LR; de Souza, SD; Dos Santos, AT; Kerntopf, MR; Quintans-Júnior, LJ; Ramos, AG; Santos Sales, V; Wanderley, AG | 1 |
| Brzozowski, T; Czekaj, R; Kwiecien, S; Magierowska, K; Magierowski, M; Majka, J; Pajdo, R; Ptak-Belowska, A; Sliwowski, Z; Surmiak, M | 1 |
| Filaretova, LP; Punin, YM; Sudalina, MN; Yarushkina, NI | 1 |
| Akiba, Y; Satoh, H; Urushidani, T | 1 |
3 review(s) available for capsaicin and indomethacin
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
Compensatory gastroprotective role of glucocorticoid hormones during inhibition of prostaglandin and nitric oxide production and desensitization of capsaicin-sensitive sensory neurons.
Topics: Adrenalectomy; Animals; Capsaicin; Corticosterone; Gastric Mucosa; Glucocorticoids; Indomethacin; Neurons, Afferent; Nitric Oxide; Prostaglandins; Rats; Stomach Ulcer | 2007 |
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine | 2013 |
6 trial(s) available for capsaicin and indomethacin
| Article | Year |
|---|---|
Tachyphylaxis to capsaicin-induced cough and its reversal by indomethacin, in patients with the sinobronchial syndrome.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Capsaicin; Chronic Disease; Cough; Female; Humans; Indomethacin; Male; Middle Aged; Syndrome; Tachyphylaxis | 1992 |
Cyclooxygenase inhibitors acetylsalicylic acid and indomethacin do not affect capsaicin-induced neurogenic inflammation in human skin.
Topics: Adult; Aspirin; Blood Flow Velocity; Capsaicin; Cyclooxygenase Inhibitors; Dermatitis, Contact; Double-Blind Method; Female; Humans; Indomethacin; Male; Prostaglandins; Skin | 1993 |
Prostanoids and cough response to capsaicin in asthma and chronic bronchitis.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Capsaicin; Chronic Disease; Cough; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Indomethacin; Male; Methacrylates; Middle Aged; Respiratory Function Tests; Thromboxane-A Synthase; Treatment Outcome | 1995 |
Gastroprotection induced by capsaicin in healthy human subjects.
Topics: Adult; Capsaicin; Cyclooxygenase Inhibitors; Cytoprotection; Dose-Response Relationship, Drug; Ethanol; Humans; Indomethacin; Middle Aged; Prospective Studies; Reference Values; Stomach Diseases | 2005 |
Mechanisms of adrenosensitivity in capsaicin induced hyperalgesia.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsaicin; Cholinergic Agents; Cross-Over Studies; Cyclooxygenase Inhibitors; Drug Interactions; Female; Humans; Hyperalgesia; Indomethacin; Iontophoresis; Male; Neurons, Afferent; Nociceptors; Norepinephrine; Pain; Prostaglandins; Sodium Chloride; Vasodilation | 2007 |
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine | 2013 |
226 other study(ies) available for capsaicin and indomethacin
| Article | Year |
|---|---|
Expanding the ChemGPS chemical space with natural products.
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
Synthesis and antinociceptive activity of capsinoid derivatives.
Topics: Analgesics; Animals; Drug Design; Esters; Female; Male; Mice; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids.
Topics: Analgesics; Animals; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Pain; Pain Threshold; Rats; Transient Receptor Potential Channels | 2017 |
Studies on gastroprotection induced by capsaicin and papaverine.
Topics: Animals; Arginine; Capsaicin; Ethanol; Female; Gastric Mucosa; Indomethacin; Male; Nitroarginine; Papaverine; Rats; Rats, Wistar; Regional Blood Flow; Stomach Ulcer | 1992 |
Omega-conotoxin-sensitive calcium channels modulate autonomic neurotransmission in guinea pig airways.
Topics: Acetylcholine; Animals; Atropine; Autonomic Nervous System; Bronchi; Calcium Channels; Capsaicin; Choline; Electric Stimulation; Epinephrine; Guanethidine; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Neurons, Afferent; Neurons, Efferent; omega-Conotoxin GVIA; Peptides, Cyclic; Propranolol; Synaptic Transmission; Tachykinins; Trachea | 1992 |
Release of calcitonin gene-related peptide like-immunoreactivity induced by electrical field stimulation from rat spinal afferents is mediated by conotoxin-sensitive calcium channels.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels; Capsaicin; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Mollusk Venoms; Neurons, Afferent; omega-Conotoxin GVIA; Potassium Chloride; Rats; Rats, Inbred Strains; Spinal Cord; Tetrodotoxin | 1992 |
Local motor responses to bradykinin and bacterial chemotactic peptide formyl-methionyl-leucyl-phenylalanine (FMLP) in the guinea-pig isolated renal pelvis and ureter.
Topics: Animals; Bradykinin; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indomethacin; Kidney Pelvis; Male; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Oligopeptides; Peptide Fragments; Ureter | 1992 |
Tachykinins and calcitonin gene-related peptide as co-transmitters in local motor responses produced by sensory nerve activation in the guinea-pig isolated renal pelvis.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Kidney Pelvis; Male; Motor Neurons; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurons, Afferent; Neurotransmitter Agents; Peptide Fragments; Potassium Chloride; Radioimmunoassay; Tachykinins | 1992 |
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation | 1992 |
Sensory nerves in the airways as a target for drug development.
Topics: Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Azepines; Bronchi; Bronchoconstriction; Capsaicin; Drug Design; Electric Stimulation; Guinea Pigs; Indomethacin; Male; Neurons, Afferent; Oligopeptides; Receptors, Opioid; Receptors, Opioid, mu; Substance P; Temperature | 1992 |
Bronchodilatation by tachykinins and capsaicin in the mouse main bronchus.
Topics: Animals; Bronchoconstriction; Capsaicin; Carbachol; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Mice; Neuropeptides; Substance P; Tachykinins | 1992 |
Stimulation by capsaicin of gastric alkaline secretion in anesthetized rats.
Topics: Afferent Pathways; Animals; Bicarbonates; Capsaicin; Denervation; Duodenum; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley | 1992 |
Induction of gastric lesions by 2-deoxy-D-glucose in rats following chemical ablation of capsaicin-sensitive sensory neurons.
Topics: Animals; Capsaicin; Denervation; Deoxyglucose; Gastric Acid; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Injections, Intravenous; Laser-Doppler Flowmetry; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1992 |
Role of capsaicin-sensitive afferent neurons in mucosal blood flow response of rat stomach induced by mild irritants.
Topics: Animals; Capsaicin; Denervation; Gastric Acidity Determination; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Irritants; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Regional Blood Flow; Sodium Chloride | 1992 |
Role of capsaicin-sensitive sensory nerves in acid-induced bicarbonate secretion in rat stomach.
Topics: Animals; Bicarbonates; Capsaicin; Denervation; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Neurons, Afferent; Rats; Rats, Inbred Strains | 1992 |
Endogenous nitric oxide and sensory neuropeptides interact in the modulation of the rat gastric microcirculation.
Topics: Animals; Arginine; Blood Pressure; Capsaicin; Gastric Mucosa; Indomethacin; Male; Microcirculation; Neurons, Afferent; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Dual effects of capsaicin on responses of the rabbit ear artery to field stimulation.
Topics: Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Ear, External; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vascular; Neurokinin A; Norepinephrine; Prostaglandins; Rabbits; Regional Blood Flow; Substance P; Sympathetic Nervous System; Synaptic Transmission | 1990 |
Suppression by neuropeptide Y of capsaicin-sensitive sensory nerve-mediated contraction in guinea-pig airways.
Topics: Animals; Atropine; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Neuropeptide Y; Propranolol; Substance P; Synaptic Transmission; Tetrodotoxin; Trachea | 1990 |
Pharmacological modulation of the contractile response to toluene diisocyanate in the rat isolated urinary bladder.
Topics: Animals; Atropine; Capsaicin; In Vitro Techniques; Indomethacin; Male; Methylprednisolone; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Ruthenium Red; Tetrodotoxin; Toluene 2,4-Diisocyanate; Urinary Bladder | 1990 |
Gastric motility changes in capsaicin-induced cytoprotection in the rat stomach.
Topics: Animals; Capsaicin; Ethanol; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Substance P | 1991 |
Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: mechanism of action and biological response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acids; Animals; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Guinea Pigs; Hydrogen-Ion Concentration; Indomethacin; Isoquinolines; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Neurosecretion; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperazines; Potassium; Ruthenium Red; Tetrodotoxin; Urinary Bladder | 1991 |
Heterogeneous involvement of endothelium in calcitonin gene-related peptide-induced relaxation in coronary arteries from rat.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Humans; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Ruthenium Red; Substance P | 1991 |
Airway hypocapnia increases microvascular leakage in the guinea pig trachea.
Topics: Animals; Capillary Permeability; Capsaicin; Carbon Dioxide; Evans Blue; Female; Glycopeptides; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Morphine; Tachykinins; Thromboxane-A Synthase; Trachea | 1992 |
Endothelium-dependent nonadrenergic, noncholinergic neural relaxation in guinea pig pulmonary artery.
Topics: Acetamides; Adenosine Triphosphate; Animals; Arginine; Atropine; Autonomic Nervous System; Capsaicin; Chymotrypsin; Drug Interactions; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth, Vascular; omega-N-Methylarginine; Phenyl Ethers; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Vasoactive Intestinal Peptide | 1992 |
Systemic capsaicin and olvanil reduce the acute algogenic and the late inflammatory phase following formalin injection into rodent paw.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Electrophysiology; Foot; Formaldehyde; Indomethacin; Inflammation; Mice; Morphine; Neurons; Pain; Spinal Cord | 1991 |
Vascular interactions between endogenous prostanoids and vasoactive peptide mediators in gastric damage.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Capsaicin; Cyclooxygenase Inhibitors; Endothelins; Gastric Mucosa; Indomethacin; Male; Neurons; Neuropeptides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Rats; Rats, Inbred Strains; Tetrodotoxin; Vasoconstriction; Vasodilation | 1991 |
Interactions between the vascular peptide endothelin-1 and sensory neuropeptides in gastric mucosal injury.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Endothelins; Gastric Mucosa; Gastrointestinal Hemorrhage; Indomethacin; Male; Morphine; Necrosis; Neuropeptides; Rats; Rats, Inbred Strains; Stomach Ulcer | 1991 |
Hyperresponsiveness to tussive stimuli in cigarette smoke-exposed guinea-pigs: a role for capsaicin-sensitive, calcitonin gene-related peptide-containing nerves.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Cough; Female; Guinea Pigs; Indomethacin; Male; Mechanoreceptors; Neurons; Neuropeptide Y; Neuropeptides; Radioimmunoassay; Reflex; Smoking; Sneezing | 1991 |
Involvement of capsaicin-sensitive nerves in the bronchomotor effects of arachidonic acid and melittin: a possible role for lipoxin A4.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzeneacetamides; Bronchi; Capsaicin; Epithelium; Guinea Pigs; Hydroxamic Acids; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Lipoxins; Lipoxygenase Inhibitors; Male; Melitten; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; SRS-A | 1991 |
The effect of capsaicin on gallbladder fluid absorption.
Topics: Absorption; Animals; Body Fluids; Buffers; Capsaicin; Cats; Gallbladder; Indomethacin; Lidocaine; Osmolar Concentration; Perfusion; Prostaglandins | 1991 |
Gastric and jejunal ultrastructure in capsaicin-treated rats with and without experimental ulcer.
Topics: Animals; Capsaicin; Denervation; Ethanol; Gastric Mucosa; Indomethacin; Jejunum; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Stomach; Stomach Ulcer | 1991 |
Pharmacologic analysis of platelet activating factor16- and 18-induced bronchoconstriction in the guinea pig.
Topics: Animals; Atropine; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukocyte Count; Lung; Male; Methysergide; Platelet Activating Factor; Platelet Count; Propranolol; Pyrilamine; Respiratory Function Tests; Thiorphan | 1991 |
Laparotomy-induced gastric protection against ethanol injury is mediated by capsaicin-sensitive sensory neurons.
Topics: Animals; Atropine; Capsaicin; Ethanol; Ganglionic Blockers; Gastric Mucosa; Guanethidine; Hexamethonium; Hexamethonium Compounds; Indomethacin; Laparotomy; Male; Neurons, Afferent; Rats; Rats, Inbred Strains | 1990 |
Stimulation of tracheal ciliary beat frequency by capsaicin.
Topics: Aerosols; Animals; Capsaicin; Dogs; Female; Hexamethonium; Hexamethonium Compounds; Indomethacin; Ipratropium; Kinetics; Male; Mucociliary Clearance; Neural Pathways; Trachea | 1990 |
Responses of rat isolated intestinal segments to stimulation of perivascular mesenteric nerve fibres.
Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Female; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indomethacin; Jejunum; Mesentery; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Phentolamine; Propranolol; Rats; Rats, Inbred Strains | 1990 |
The role of capsaicin-sensitive afferent nerves in protective effect of capsaicin against absolute ethanol-induced gastric lesions in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Disease Models, Animal; Ethanol; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Stomach Diseases | 1991 |
Non-adrenergic, non-cholinergic contractions in the electrically field stimulated guinea-pig trachea.
Topics: Animals; Atropine; Autonomic Nervous System; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; Propranolol; Tetrodotoxin; Trachea | 1990 |
Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat.
Topics: Animals; Arginine; Blood Pressure; Capsaicin; Epoprostenol; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Neuropeptides; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
Distension-induced secretion in the rat colon: mediation by prostaglandins and submucosal neurons.
Topics: Animals; Anthracenes; Arachidonic Acid; Arachidonic Acids; Atropine; Bufanolides; Capsaicin; Colon; Electrophysiology; Female; Half-Life; Indomethacin; Intestinal Mucosa; Neurons; Phospholipases A; Phospholipases A2; Prostaglandins; Quinacrine; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
Bradykinin-induced bronchoconstriction in guinea pig in vivo: role of neural mechanisms.
Topics: Animals; Atropine; Bradykinin; Bronchi; Bronchial Provocation Tests; Capsaicin; Constriction, Pathologic; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Injections, Intravenous; Instillation, Drug; Male; Propranolol | 1990 |
Possible involvement of substance P in the contraction produced by periarterial nerve stimulation in the rat ileum.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Electric Stimulation; Guanethidine; Ileum; In Vitro Techniques; Indomethacin; Male; Mesentery; Muscle Contraction; Muscle, Smooth; Physostigmine; Rats; Rats, Inbred Strains; Substance P; Synaptic Transmission; Tetraethylammonium Compounds | 1985 |
Further studies on the mechanisms of the tachykinin-induced activation of micturition reflex in rats: evidence for the involvement of the capsaicin-sensitive bladder mechanoreceptors.
Topics: Aging; Animals; Capsaicin; Diphenhydramine; Electric Stimulation; In Vitro Techniques; Indomethacin; Kassinin; Male; Mechanoreceptors; Neurokinin A; Neurokinin B; Neuropeptides; Oligopeptides; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder; Urination | 1987 |
Influence of epithelium on guinea pig airway responses to tachykinins: role of endopeptidase and cyclooxygenase.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Endopeptidases; Epithelium; Glycopeptides; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Prostaglandin-Endoperoxide Synthases; Substance P; Tachykinins; Trachea | 1989 |
Enhanced airway responses to substance P after repeated challenge in guinea pigs.
Topics: Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Lung Compliance; Male; Muscle Contraction; Pyrilamine; Respiratory Physiological Phenomena; Respiratory System; Substance P | 1989 |
Modified formalin test: characteristic biphasic pain response.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bromelains; Capsaicin; Dexamethasone; Dose-Response Relationship, Drug; Formaldehyde; Indomethacin; Male; Mice; Morphine; Nerve Fibers; p-Methoxy-N-methylphenethylamine; Pain; Pain Measurement; Sciatic Nerve; Substance P; Time Factors | 1989 |
Multiple mechanisms in the motor responses of the guinea-pig isolated urinary bladder to bradykinin.
Topics: Animals; Apamin; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; Indomethacin; Kallidin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Substance P; Tetrodotoxin; Thiorphan; Urinary Bladder | 1989 |
Prostaglandins and CGRP release from cardiac sensory nerves.
Topics: Alprostadil; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Disease; Epoprostenol; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Myocardium; Neurons, Afferent; Neuropeptide Y; Ouabain; Prostaglandins; Sympathetic Nervous System | 1989 |
Pharmacological studies on nonimmunologic contact urticaria in guinea pigs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Capsaicin; Chlorpheniramine; Dermatitis, Contact; Dexamethasone; Female; Guinea Pigs; Indomethacin; Male; Premedication; Pyrazoles; Ranitidine; Urticaria | 1986 |
Prostanoids modulate reflex micturition by acting through capsaicin-sensitive afferents.
Topics: Animals; Capsaicin; Dinoprostone; Indomethacin; Male; Prostaglandins E; Rats; Reflex; Thromboxane B2; Urinary Bladder; Urination | 1988 |
Further studies on the role of the adrenals in the capsaicin-sensitive "gastric defence mechanism".
Topics: Adrenal Glands; Animals; Aspirin; Capsaicin; Drug Synergism; Ethanol; Indomethacin; Rats; Rats, Inbred Strains; Stomach Ulcer | 1988 |
The involvement of afferent nerve terminals in the stimulation of ion transport by bradykinin in rat isolated colon.
Topics: Animals; Bradykinin; Capsaicin; Colon; In Vitro Techniques; Indomethacin; Male; Nerve Endings; Neurons, Afferent; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium Chloride; Stimulation, Chemical; Tetrodotoxin | 1988 |
Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons.
Topics: Animals; Capsaicin; Cysteamine; Dinoprostone; Duodenal Ulcer; Epoprostenol; Ethanol; Female; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer | 1986 |
The role of the capsaicin-sensitive innervation of the rat urinary bladder in the activation of micturition reflex.
Topics: Acetylcholine; Animals; Capsaicin; Cimetidine; Denervation; Diphenhydramine; Indomethacin; Injections, Intraventricular; Male; Motor Activity; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Urinary Bladder | 1986 |
Role of prostaglandins in initiating cardiovascular reflexes originating from the pancreas and the gall bladder.
Topics: Animals; Blood Pressure; Bradykinin; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Cats; Gallbladder; Heart Rate; Indomethacin; Pancreas; Prostaglandins | 1986 |
Evidence for a role of adrenals in the capsaicin-sensitive "gastric defence mechanism" in rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Capsaicin; Indomethacin; Male; Rats; Rats, Inbred Strains; Stomach Ulcer | 1986 |
Involvement of capsaicin-sensitive mechanism(s) in the antiulcer defence of intestinal mucosa in rats.
Topics: Animals; Capsaicin; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains; Ulcer | 1987 |
Modulation of reflex renal vasoconstriction by increased endogenous renal prostaglandin synthesis.
Topics: Animals; Capsaicin; Dogs; Electric Stimulation; Female; Heart Rate; Indomethacin; Kidney; Male; Prostaglandins; Reflex; Renal Circulation; Sciatic Nerve; Ureteral Obstruction; Vasoconstriction | 1985 |
Antihemostatic and antithrombotic effects of capsaicin in comparison with aspirin and indomethacin.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Capsaicin; Hemostasis; Indomethacin; Mice; Mice, Inbred ICR; Platelet Aggregation; Thromboembolism; Thrombosis | 1985 |
Involvement of capsaicin-sensitive afferent neurones in a vagal-dependent interaction between leukotriene D4 and histamine on bronchomotor tone.
Topics: Airway Resistance; Animals; Bronchi; Capsaicin; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Indomethacin; Male; Nerve Fibers; Neurons, Afferent; SRS-A; Substance P; Vagus Nerve | 1984 |
A study of the atropine-resistant component of the neurogenic response of the rabbit urinary bladder.
Topics: Animals; Atropine; Capsaicin; Chlorpheniramine; Drug Resistance; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Neurotransmitter Agents; Rabbits; Urinary Bladder | 1984 |
The pathophysiological effects of nitrogen mustard on the rabbit eye. II. The inhibition of the initial hypertensive phase by capsaicin and the apparent role of substance P.
Topics: Animals; Capsaicin; Denervation; Ethanol; Eye; Fatty Acids, Unsaturated; Indomethacin; Intraocular Pressure; Mechlorethamine; Pupil; Rabbits; Substance P | 1980 |
Ocular responses to antidromic trigeminal stimulation, intracameral prostaglandin E1 and E2, capsaicin and substance P.
Topics: Animals; Capsaicin; Fatty Acids, Unsaturated; Female; Indomethacin; Intraocular Pressure; Male; Miotics; Neural Conduction; Prostaglandins E; Prostaglandins F; Pupil; Rabbits; Substance P; Tetrodotoxin; Trigeminal Nerve; Uveitis | 1981 |
Effect of neonatal treatment with capsaicin on carrageenan-induced paw oedema in the rat.
Topics: Animals; Animals, Newborn; Capsaicin; Carrageenan; Edema; Histamine Release; Indomethacin; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Time Factors | 1984 |
A mechanism for sympathectomy-induced bone resorption in the middle ear.
Topics: Animals; Animals, Newborn; Awards and Prizes; Bone and Bones; Bone Resorption; Calcium; Capsaicin; Cell Count; Culture Media; Ear, Middle; Gerbillinae; Hearing Disorders; Humans; In Vitro Techniques; Indomethacin; Mice; Nerve Growth Factors; Neuropeptides; Osteoclasts; Oxidopamine; Skull; Substance P; Sympathetic Nervous System | 1995 |
Pharmacological studies of allergic cough in the guinea pig.
Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsaicin; Chlorpheniramine; Cimetidine; Codeine; Cough; Drug Hypersensitivity; Guinea Pigs; Hexamethonium; Histamine Antagonists; Indomethacin; Injections, Subcutaneous; Ipratropium; Loratadine; Male; Ovalbumin; Piperidines; Receptors, Histamine H1; Receptors, Histamine H2 | 1995 |
Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema.
Topics: Administration, Cutaneous; Animals; Arachidonic Acid; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cyproheptadine; Edema; Indomethacin; Male; Mice; Neuropeptides; Nifedipine; Substance P | 1993 |
Contractile effects of bradykinin on the isolated human small bronchus.
Topics: Acetylcholine; Aged; Atropine; Benzamides; Biphenyl Compounds; Bradykinin; Bronchi; Bronchoconstriction; Capsaicin; Humans; In Vitro Techniques; Indomethacin; Middle Aged; Muscle, Smooth; Nerve Fibers; Neurokinin A; Neurons, Afferent; Piperidines; Receptors, Bradykinin; Ruthenium Red; Tetrodotoxin | 1994 |
Capsaicin sensitive nerves in the jejunum of Nippostrongylus brasiliensis-sensitized rats participate in a cardiovascular depressor reflex.
Topics: Anaphylaxis; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Diterpenes; Ginkgolides; Guanethidine; Hemodynamics; Indomethacin; Jejunum; Lactones; Male; Neurons, Afferent; Nippostrongylus; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Reflex; Ruthenium Red; Strongylida Infections | 1993 |
The differential mechanisms of mild irritants on adaptive cytoprotection.
Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P | 1994 |
An investigation into the mechanism of capsaicin-induced oedema in rabbit skin.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Catalase; Dexamethasone; Drug Interactions; Edema; Histamine; Indoles; Indomethacin; Injections, Intradermal; Injections, Intravenous; Isoindoles; Male; Piperidines; Rabbits; Regional Blood Flow; Ruthenium Red; Skin; Substance P; Vasodilator Agents | 1995 |
Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Indoles; Indomethacin; Injections, Spinal; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Quinuclidines; Rats; Rats, Wistar; Reflex; Substance P; Urinary Bladder | 1995 |
Role of thromboxane A2 in bradykinin-induced human isolated small bronchi contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Biphenyl Compounds; Bradykinin; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Imidazoles; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Ruthenium Red; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents | 1995 |
Roles of prostaglandins, nitric oxide and the capsaicin-sensitive sensory nerves in gastroprotection produced by ecabet sodium.
Topics: 16,16-Dimethylprostaglandin E2; Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arginine; Capsaicin; Dinoprostone; Diterpenes; Drug Interactions; Ethanol; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Neurons, Afferent; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 1995 |
Effect of frusemide on bradykinin- and capsaicin-induced contraction of the guinea-pig trachea.
Topics: Animals; Bradykinin; Bronchoconstriction; Capsaicin; Furosemide; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Substance P; Trachea | 1993 |
Role of prostaglandins in renal sensory receptor activation by substance P and bradykinin.
Topics: Animals; Bradykinin; Capsaicin; Denervation; Dose-Response Relationship, Drug; Indomethacin; Kidney; Male; Nervous System; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Substance P | 1993 |
Capsaicin-activated bronchial- and alveolar-initiated pathways regulating tracheal ciliary beat frequency.
Topics: Aerosols; Animals; Bronchi; Capsaicin; Cilia; Cromolyn Sodium; Dogs; Hexamethonium; Indomethacin; Ipratropium; Lasers; Neural Pathways; Propranolol; Pulmonary Alveoli; Scattering, Radiation | 1994 |
Multiple mechanisms for the effects of capsaicin, bradykinin and nicotine on CGRP release from tracheal afferent nerves: role of prostaglandins, sympathetic nerves and mast cells.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Indomethacin; Male; Mast Cells; Neurons, Afferent; Nicotine; Oxidopamine; p-Methoxy-N-methylphenethylamine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Trachea | 1994 |
Calcitonin gene-related peptide: a neurotransmitter involved in capsaicin-sensitive afferent nerve-mediated gastric mucosal protection.
Topics: Afferent Pathways; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Mucosa; Indomethacin; Rats; Rats, Wistar; Regional Blood Flow; Somatostatin; Synaptic Transmission | 1993 |
Mechanisms of relaxation by pyrogallol and methylthioninium chloride in perfused rat mesenteric artery.
Topics: Animals; Arginine; Capsaicin; Catalase; Deferoxamine; Dose-Response Relationship, Drug; Indomethacin; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Nitroarginine; Pyrogallol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 1994 |
Interleukin-1 beta enhances capsaicin-induced neurogenic vasodilatation in the rat skin.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Drug Synergism; Female; Hyperemia; Indomethacin; Interleukin-1; Muscle, Smooth, Vascular; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Skin; Stimulation, Chemical; Vasodilation | 1994 |
Capsaicin-sensitive sensory nerves in recovery of gastric mucosal integrity after damage by sodium taurocholate in rats.
Topics: Animals; Capsaicin; Denervation; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Membrane Potentials; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Taurocholic Acid | 1993 |
Activation of cardiac vagal afferents by oxygen-derived free radicals in rats.
Topics: Afferent Pathways; Animals; Capsaicin; Deferoxamine; Female; Heart; Heart Ventricles; Hydrogen Peroxide; Indomethacin; Male; Mechanoreceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Vagus Nerve; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Cyclo-oxygenase products released by low pH have capsaicin-like actions on sensory nerves in the isolated guinea pig heart.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Diclofenac; Epoprostenol; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Indomethacin; Lactates; Lactic Acid; Neurons, Afferent; Perfusion; Receptors, Drug | 1994 |
Potentiation of sensory tachykininergic and parasympathetic cholinergic transmission by epidermal growth factor.
Topics: Acetylcholine; Alprostadil; Animals; Atropine; Capsaicin; Epidermal Growth Factor; Female; Genistein; In Vitro Techniques; Indomethacin; Iris; Isoflavones; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Rabbits; Synaptic Transmission; Tachykinins | 1993 |
Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis.
Topics: Aerosols; Animals; Capsaicin; Guinea Pigs; In Vitro Techniques; Indomethacin; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Stress, Mechanical; Trachea | 1993 |
Interleukin-1 receptor antagonist does not prevent endotoxin-induced inhibition of gastric acid secretion in rats.
Topics: Afferent Pathways; Animals; Capsaicin; Endotoxins; Escherichia coli; Gastric Acid; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Male; Naloxone; Premedication; Rats; Receptors, Interleukin-1; Receptors, Opioid; Recombinant Proteins; Sialoglycoproteins | 1994 |
Regulation of gastroduodenal bicarbonate secretion by capsaicin-sensitive sensory neurons in rats.
Topics: Afferent Pathways; Animals; Bicarbonates; Capsaicin; Denervation; Dose-Response Relationship, Drug; Duodenum; Gastric Acidity Determination; Gastric Mucosa; Histamine; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells | 1993 |
A role for calcitonin gene-related peptide in protection against gastric ulceration.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1994 |
Sensory neuron-mediated gastric mucosal protection is blocked by cyclooxygenase inhibition.
Topics: Administration, Topical; Animals; Bile Acids and Salts; Capsaicin; Cyclooxygenase Inhibitors; DNA; Gastric Mucosa; Indomethacin; Lidocaine; Nerve Block; Neurons, Afferent; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 1994 |
The effect of intra-articular capsaicin on passive synovial anaphylaxis and blood flow in the rat knee joint.
Topics: Anaphylaxis; Animals; Capsaicin; Cell Degranulation; Guanethidine; Hindlimb; Immunoglobulin E; Indicators and Reagents; Indomethacin; Injections, Intra-Articular; Male; Mast Cells; Rats; Rats, Wistar; Regional Blood Flow; Synovitis | 1993 |
Role of calcitonin gene-related peptide and nitric oxide in the gastroprotective effect of capsaicin in the rat.
Topics: Animals; Antibodies; Arginine; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Mucosa; Indomethacin; Male; Nitric Oxide; Nitroarginine; Peptide Fragments; Rats; Receptors, Calcitonin; Receptors, Cell Surface; Recombinant Proteins; Stomach Diseases | 1993 |
Evidence for sensory nerve involvement in cutaneous reactive hyperemia in humans.
Topics: Adult; Anesthesia, Local; Calcitonin Gene-Related Peptide; Capsaicin; Constriction; Humans; Hyperemia; Indomethacin; Laser-Doppler Flowmetry; Male; Regional Blood Flow; Skin | 1993 |
Role of nitric oxide and prostaglandins in gastroprotection induced by capsaicin and papaverine.
Topics: Animals; Arginine; Capsaicin; Ethanol; Female; Gastric Mucosa; Indomethacin; Male; Nitric Oxide; Nitroarginine; Papaverine; Prostaglandins; Rats; Rats, Wistar; Regional Blood Flow | 1993 |
Nitric oxide and sensory afferent neurones modulate the protective effects of low-dose endotoxin on rat gastric mucosal damage.
Topics: Analysis of Variance; Animals; Arginine; Capsaicin; Dexamethasone; Endotoxins; Enzyme Inhibitors; Escherichia coli; Ethanol; Female; Gastric Mucosa; Indomethacin; Injections, Intraperitoneal; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1995 |
Stable VIP analogue Ro-24-9981 potentiates substance P-induced plasma exudation in hamster cheek pouch.
Topics: Animals; Arginine; Calcimycin; Capsaicin; Cheek; Cricetinae; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethacin; Ionophores; Male; Microcirculation; Mouth Mucosa; NG-Nitroarginine Methyl Ester; Peptides, Cyclic; Plasma; Substance P; Vasoactive Intestinal Peptide | 1995 |
Substance P enhances electrical field stimulation-induced mast cell degranulation in rat trachea.
Topics: Animals; Biphenyl Compounds; Capsaicin; Cell Degranulation; Chymotrypsin; Dose-Response Relationship, Drug; Electric Stimulation; Indomethacin; Male; Mast Cells; Neurokinin A; Neurokinin-1 Receptor Antagonists; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Substance P; Trachea | 1996 |
Beneficial effect of a novel pentadecapeptide BPC 157 on gastric lesions induced by restraint stress, ethanol, indomethacin, and capsaicin neurotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Capsaicin; Ethanol; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Peptide Fragments; Proteins; Rats; Rats, Wistar; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Physiological | 1996 |
Implication of sensory neurons in the diverse mechanisms of adaptive cytoprotection in the rat stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Capsaicin; Cell Differentiation; Cyclooxygenase Inhibitors; Denervation; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Stomach | 1996 |
Pharmacology of calcitonin gene related peptide release from sensory terminals in the rat trachea.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Indomethacin; Male; Nerve Fibers; Oxidopamine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Trachea | 1995 |
Cardiac sympathetic afferent reflex in dogs with congestive heart failure.
Topics: Afferent Pathways; Animals; Blood Pressure; Bradykinin; Capsaicin; Dogs; Female; Heart Conduction System; Heart Failure; Heart Rate; Hemodynamics; Indomethacin; Kidney; Male; Reference Values; Reflex; Sympathetic Nervous System | 1996 |
Mucosal irritation, adaptive cytoprotection, and adaptation to topical ammonia in the rat stomach.
Topics: Adaptation, Physiological; Administration, Topical; Ammonia; Animals; Capsaicin; Cyclooxygenase Inhibitors; Epidermal Growth Factor; Ethanol; Female; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Indomethacin; Irritants; Male; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandins; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H2; Stomach; Transforming Growth Factor alpha; Urease | 1996 |
Renal sympathetic nerve activity during cardiac ischemia and reperfusion in rats.
Topics: Administration, Topical; Animals; Blood Pressure; Capsaicin; Deferoxamine; Denervation; Heart Conduction System; Heart Rate; Indomethacin; Kidney; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1996 |
Nitric oxide, prostaglandin, and sensory neurons in gastric mucosal blood flow response during acid secretion in rats.
Topics: Animals; Capsaicin; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Omeprazole; Pentagastrin; Prostaglandins; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley | 1997 |
Pre- and postjunctional inhibitory effects of fenspiride on guinea-pig bronchi.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Nerve Fibers; Neurokinin A; Neuropeptides; Peptide Fragments; Propranolol; Spiro Compounds; Substance P | 1997 |
The indomethacin-induced gastric mucosal damage in rats. Effect of gastric acid, acid inhibition, capsaicin-type agents and prostacyclin.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diterpenes; Epoprostenol; Female; Gastric Acid; Gastric Mucosa; Histamine; Hydrochloric Acid; Indomethacin; Isoproterenol; Laser-Doppler Flowmetry; Male; Microcirculation; Neurotoxins; Pentagastrin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach Ulcer; Vasodilator Agents | 1997 |
Pharmacology and mode of action of bradykinin on mouse-isolated trachea.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; In Vitro Techniques; Indoles; Indomethacin; Isoindoles; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Receptors, Bradykinin; Trachea | 1997 |
Involvement of prostaglandins and CGRP-dependent sensory afferents in peritoneal irritation-induced visceral pain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; Colic; Dose-Response Relationship, Drug; Indomethacin; Male; Morphine; Pain; Peritoneum; Prostaglandins; Pyrrolidines; Rats; Rats, Sprague-Dawley; Viscera | 1997 |
Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing.
Topics: Animals; Arginine; Capsaicin; Citrulline; Dose-Response Relationship, Drug; Endothelium; Gastric Acid; Gastric Mucosa; Glutamine; Immunohistochemistry; Indomethacin; Male; Neovascularization, Pathologic; Neurons, Afferent; Nitroarginine; Ornithine; Pepsin A; Rats; Rats, Wistar; Ulcer | 1997 |
Mechanisms mediating gastric hyperemic and acid responses to central TRH analog at a cytoprotective dose.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Acid; Gastric Mucosa; Hemodynamics; Hyperemia; Indomethacin; Male; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Thyrotropin-Releasing Hormone; Time Factors; Vascular Resistance | 1997 |
Enhanced responsiveness of cardiac vagal chemosensitive endings to bradykinin in heart failure.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Captopril; Cardiac Output, Low; Dogs; Female; Heart Conduction System; Hemodynamics; Indomethacin; Male; Nerve Endings; Vagus Nerve | 1997 |
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidine; Dexamethasone; Diphenhydramine; Edema; Enterotoxins; Enzyme Inhibitors; Hindlimb; Histamine Antagonists; Indomethacin; Inflammation; Male; Mice; Platelet Aggregation Inhibitors; Triazoles | 1997 |
Neurochemical mechanisms of nitroglycerin-induced neuronal activation in rat brain: a pharmacological investigation.
Topics: Animals; Capsaicin; Central Nervous System Stimulants; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Ephedrine; Hippocampus; Indomethacin; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1997 |
Effects of KB-2796 on plasma extravasation following antidromic trigeminal stimulation in the rat.
Topics: Animals; Calcium Channel Blockers; Capillary Permeability; Capsaicin; Electric Stimulation; Glycopeptides; Indomethacin; Migraine Disorders; Piperazines; Rats; Skin; Trigeminal Ganglion | 1997 |
Capsaicin can abolish spontaneous tone in guinea-pig trachealis.
Topics: Animals; Atropine; Capsaicin; Cyclooxygenase Inhibitors; Drug Interactions; Glycopeptides; Guinea Pigs; Indomethacin; Male; Models, Biological; Muscle Tonus; Propranolol; Prostaglandins; Protease Inhibitors; Tachykinins; Tetrodotoxin; Trachea | 1998 |
Pharmacologic characterization of latex extracts by isolated guinea pig tracheal tissue.
Topics: Animals; Arachidonic Acids; Atropine; Capsaicin; Cholinergic Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gallic Acid; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Isoxazoles; Latex; Leukotriene Antagonists; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrilamine; Trachea | 1998 |
Vagal mechanisms underlying gastric protection induced by chemical activation of raphe pallidus in rats.
Topics: Afferent Pathways; Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Ethanol; Gastric Acid; Gastric Mucosa; Indomethacin; Injections, Intravenous; Kainic Acid; Male; Microinjections; NG-Nitroarginine Methyl Ester; Peptide Fragments; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vagotomy; Vagus Nerve | 1998 |
Cellular pathways of mast cell- and capsaicin-sensitive nerve-evoked ileal submucosal arteriolar dilations.
Topics: Alprostadil; Animals; Arterioles; Bradykinin; Capsaicin; Cattle; Epoprostenol; Food Hypersensitivity; Guinea Pigs; Ileum; Indomethacin; Lactoglobulins; Mast Cells; Microscopy, Video; Milk; Muscle, Smooth; Neurons; omega-N-Methylarginine; Pyrilamine; Serotonin; Vasodilation | 1998 |
Gastroprotective actions of bombesin, L-DOPA, and mild irritants: roles of prostaglandins and sensory neurons.
Topics: Adaptation, Physiological; Animals; Bombesin; Capsaicin; Cyclooxygenase Inhibitors; Dopamine Agents; Ethanol; Female; Indomethacin; Irritants; Levodopa; Neurons, Afferent; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Stomach | 1998 |
Biphasic relaxant response of ovine trachealis muscle to electrical field stimulation: influence of cooling.
Topics: Analysis of Variance; Animals; Atropine; Capsaicin; Carbachol; Cold Temperature; Electric Stimulation; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propranolol; Serotonin; Serotonin Antagonists; Sheep; Tetrodotoxin; Trachea | 1999 |
Calcitonin gene-related peptide protects cultured rat gastric mucosal cells.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ethanol; Gastric Mucosa; Indomethacin; Rats; Substance P | 1998 |
Physiological oxygen concentration gives an oscillating spontaneous tone in guinea-pig tracheal preparations.
Topics: Animals; Capsaicin; Electric Stimulation; Guinea Pigs; Heptanol; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Tonus; Muscle, Smooth; Oscillometry; Oxygen; Tetrodotoxin; Trachea | 1999 |
The inhibition of nicotine-evoked relaxation of the guinea-pig isolated basilar artery by some analgesic drugs and progesterone.
Topics: Analgesics; Animals; Aspirin; Basilar Artery; Capsaicin; Dinoprost; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Migraine Disorders; NG-Nitroarginine Methyl Ester; Nicotine; Progesterone; Substance P; Sumatriptan; Vasodilation | 1999 |
Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in rats.
Topics: Animals; Anti-Bacterial Agents; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escin; Ethanol; Ethylmaleimide; Gastric Mucosa; Gastrointestinal Agents; Indomethacin; Ligation; Male; NG-Nitroarginine Methyl Ester; Pylorus; Rats; Rats, Sprague-Dawley; Stomach Diseases; Streptozocin | 1999 |
Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Capsaicin; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oleanolic Acid; Premedication; Prostaglandins; Rats; Rats, Sprague-Dawley; Stomach Diseases; Sulfhydryl Compounds | 1999 |
Gastroprotective mechanism of lafutidine, a novel anti-ulcer drug with histamine H2-receptor antagonistic activity.
Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Ammonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Capsaicin; Central Nervous System Depressants; Ethanol; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Male; Membrane Potentials; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1999 |
Cardiac sympathetic afferent sensitivity is enhanced in heart failure.
Topics: Afferent Pathways; Animals; Bradykinin; Capsaicin; Cardiac Output, Low; Cyclooxygenase Inhibitors; Dogs; Electrophysiology; Female; Heart Conduction System; Hemodynamics; Indomethacin; Male; Sympathetic Nervous System | 1999 |
Antiulcer effect of lafutidine on indomethacin-induced gastric antral ulcers in refed rats.
Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Administration, Oral; Animals; Anti-Ulcer Agents; Capsaicin; Cimetidine; Denervation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Famotidine; Food; Indomethacin; Male; Nitroarginine; Piperidines; Pyloric Antrum; Pyridines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Wound Healing | 1999 |
The role of protease-activated receptor-2 (PAR2) in the modulation of beating of the mouse isolated ureter: lack of involvement of mast cells or sensory nerves.
Topics: Animals; Capsaicin; Histamine; Immunohistochemistry; In Vitro Techniques; Indomethacin; Male; Mast Cells; Mice; Mice, Inbred BALB C; Neurons, Afferent; Nitroarginine; Oligopeptides; Receptor, PAR-2; Receptors, Thrombin; Trypsin; Ureter | 1999 |
Protective effect of lafutidine against indomethacin-induced intestinal ulceration in rats: relation to capsaicin-sensitive sensory neurons.
Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Ampicillin; Animals; Capsaicin; Dose-Response Relationship, Drug; Duodenal Ulcer; Histamine H2 Antagonists; Indomethacin; Intestinal Mucosa; Male; Neurons, Afferent; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley | 2000 |
Nitric oxide prevents rat duodenal contractions induced by potentially noxious agents.
Topics: Animals; Arginine; Bicarbonates; Capsaicin; Carbon Dioxide; Chromium Radioisotopes; Crosses, Genetic; Duodenum; Edetic Acid; Ethanol; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Intubation, Gastrointestinal; Male; Metabolic Clearance Rate; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 2000 |
The role of sensory neurons in the antiulcer effect of centrally injected amylin in rat.
Topics: Adrenergic alpha-Antagonists; Amyloid; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Capsaicin; Domperidone; Indomethacin; Islet Amyloid Polypeptide; Male; Neostigmine; Neurons, Afferent; Peptide Fragments; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Yohimbine | 2000 |
Capsaicin and nonivamide as novel skin permeation enhancers for indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Enzyme Inhibitors; Female; In Vitro Techniques; Indomethacin; Irritants; Mice; Mice, Nude; Nitric Oxide Synthase; Skin; Skin Absorption; Skin Irritancy Tests; Ultrasonics | 2001 |
Mechanism of prolonged vasorelaxation to ATP in the rat isolated mesenteric arterial bed.
Topics: Adenosine Triphosphate; Animals; Capsaicin; Cardiotonic Agents; Cardiovascular Agents; Charybdotoxin; Drug Interactions; Electric Stimulation; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Mesenteric Arteries; Neurons, Afferent; Ouabain; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Tetraethylammonium; Theophylline; Vasodilation | 2001 |
Role of vagal C-fiber afferents in the bronchomotor response to lactic acid in the newborn dog.
Topics: Animals; Animals, Newborn; Atropine; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Chemoreceptor Cells; Cyclooxygenase Inhibitors; Denervation; Dogs; Electrocardiography; Indomethacin; Lactic Acid; Nerve Fibers; Neurons, Afferent; Osmolar Concentration; Respiratory Function Tests; Vagus Nerve | 2001 |
Serum-mediated relaxant response to toluene diisocyanate (TDI) in isolated guinea-pig bronchi.
Topics: Albumins; Analysis of Variance; Animals; Blood Proteins; Bronchi; Capsaicin; Culture Techniques; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Tachykinins; Toluene 2,4-Diisocyanate | 2001 |
Mouse macrophages release a neutrophil chemotactic mediator following stimulation by staphylococcal enterotoxin type A.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzamides; Calcium; Capsaicin; Chemotactic Factors; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Dexamethasone; Drug Stability; Enterotoxins; Glucocorticoids; Glucose; Indomethacin; Macrophages, Peritoneal; Magnesium; Male; Mice; Molecular Weight; Neutrophils; Piperidines; Receptors, Neurokinin-2; Thioglycolates | 2001 |
A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Bronchi; Calcium Channel Blockers; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; In Vitro Techniques; Indomethacin; Lipoxygenase; Muscle Contraction; Oxazepines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Drug; Rimonabant; Thiorphan | 2001 |
Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves.
Topics: Adenosine; Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Digestive System; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Sulfones; Theophylline; Time Factors | 2001 |
Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries.
Topics: Amides; Animals; Arachidonic Acids; Capsaicin; Coronary Vessels; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Ethanolamines; Gap Junctions; Glycyrrhetinic Acid; In Vitro Techniques; Indoles; Indomethacin; Male; Palmitic Acids; Peptides; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Tetraethylammonium; Vasodilation | 2001 |
Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Animals; Apamin; Arachidonic Acid; Arachidonic Acids; Barium; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Potassium; Potassium Channel Blockers; Potassium Channels; Pyrazoles; Receptors, Drug; Rimonabant; Sheep; Tetraethylammonium; Vasoconstrictor Agents; Vasodilation | 2001 |
Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing responses of mice.
Topics: Acetic Acid; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Benzoquinones; Bradykinin; Capsaicin; Disease Models, Animal; Female; Indomethacin; Lactic Acid; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Propionates; Prostaglandins; Receptors, Drug; Receptors, Prostaglandin | 2001 |
Role of calcitonin gene-related peptide in prostaglandins-mediated ischemic preconditioning in guinea pig hearts.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Coronary Circulation; Cyclooxygenase Inhibitors; Endothelin-1; Guinea Pigs; Heart Rate; In Vitro Techniques; Indomethacin; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Peptide Fragments; Protective Agents | 2001 |
Triphasic vascular responses to bradykinin in the mesenteric resistance artery of the rat.
Topics: Animals; Benzoquinones; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Endothelium, Vascular; Heptanoic Acids; Indomethacin; Male; Mesenteric Arteries; Nitroarginine; Peptide Fragments; Perfusion; Pyridines; Rats; Rats, Wistar; Vascular Resistance | 2001 |
Cyclo-oxygenase- and capsaicin-sensitive afferent fibres affect Beta-adrenoceptor-evoked response in the rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Indomethacin; Isoproterenol; Male; Muscle, Smooth; Neurokinin A; Papaverine; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Ruthenium Red; Urinary Bladder; Visceral Afferents | 2002 |
Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Biological Factors; Capsaicin; Drug Synergism; Endocannabinoids; Enzyme Inhibitors; Gap Junctions; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Ruthenium Red; Vasodilation; Vasodilator Agents | 2002 |
Ischemia/reperfusion-induced increase in the hepatic level of prostacyclin is mainly mediated by activation of capsaicin-sensitive sensory neurons in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Epoprostenol; Guanidines; Indomethacin; Isoenzymes; Liver; Liver Circulation; Male; Membrane Proteins; Miotics; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrobenzenes; Peptide Fragments; Peroxidase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reperfusion Injury; Specific Pathogen-Free Organisms; Sulfonamides; Transaminases; Tumor Necrosis Factor-alpha | 2002 |
Published meta-analyses of pharmacological therapies for osteoarthritis.
Topics: Acetaminophen; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chondroitin Sulfates; Cyclooxygenase Inhibitors; Glucosamine; Humans; Indomethacin; Meta-Analysis as Topic; Osteoarthritis; Osteoarthritis, Knee; Randomized Controlled Trials as Topic | 2002 |
Evidence for the involvement of a macrophage-derived chemotactic mediator in the neutrophil recruitment induced by staphylococcal enterotoxin B in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzeneacetamides; Capsaicin; Chemotaxis, Leukocyte; Cimetidine; Dexamethasone; Diterpenes; Enterotoxins; Enzyme Inhibitors; Ginkgolides; Hydroxamic Acids; Indomethacin; Interleukin-8; Lactones; Macrophages, Peritoneal; Male; Mice; Neutrophil Infiltration; Piperidines; Quinuclidines; Rats; Rats, Wistar | 2002 |
Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cytoprotection; Digestive System; Epoprostenol; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Mice; Mice, Knockout; Prostaglandins; Protective Agents; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Regional Blood Flow; Stomach Diseases | 2003 |
Mechanisms of transforming growth factor-alpha (TGF-alpha) induced gastroprotection against ethanol in the rat: roles of sensory neurons, sensory neuropeptides, and prostaglandins.
Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Ethanol; Gastric Mucosa; Gastritis; Indomethacin; Injections, Intraperitoneal; Male; Neurons, Afferent; Neuropeptides; Probability; Prostaglandins; Radionuclide Imaging; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Stomach; Substance P; Transforming Growth Factor alpha | 2003 |
Endogenous prostaglandin I2 regulates the neural emergency system through release of calcitonin gene related peptide.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epoprostenol; Ethanol; Gastric Mucosa; Indomethacin; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Antinociceptive profile of (-)-spectaline: a piperidine alkaloid from Cassia leptophylla.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Capsaicin; Cassia; Dipyrone; Dose-Response Relationship, Drug; Flowers; Formaldehyde; Fruit; Hot Temperature; Indomethacin; Male; Mice; Pain; Phytotherapy; Piperidines; Plant Extracts | 2003 |
Biphasic response of cutaneous blood flow induced by passive cutaneous anaphylaxis in rats.
Topics: Animals; Animals, Newborn; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Heart Rate; Indomethacin; Male; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred BN; Rats, Wistar; Skin | 2003 |
Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.
Topics: Administration, Oral; Animals; Body Weight; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Acid; Gastric Mucosa; Gastritis; Gene Expression; Indomethacin; Injections, Subcutaneous; Iodoacetamide; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach Ulcer; Sulfones; Vagotomy | 2004 |
Regulation of calcitonin gene-related peptide release from rat trigeminal nucleus caudalis slices in vitro.
Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; In Vitro Techniques; Indomethacin; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Trigeminal Caudal Nucleus | 2004 |
The effect of a chromogranin A-derived peptide (CgA4-16) in the writhing nociceptive response induced by acetic acid in rats.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels, L-Type; Capsaicin; Chromogranin A; Chromogranins; Diltiazem; Dose-Response Relationship, Drug; Indomethacin; Injections, Intraperitoneal; Male; Pain Measurement; Peptide Fragments; Rats; Rats, Wistar; Substance P | 2004 |
Ischemic preconditioning of remote organs attenuates gastric ischemia-reperfusion injury through involvement of prostaglandins and sensory nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Dinoprostone; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Sulfones; Tumor Necrosis Factor-alpha | 2004 |
Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons.
Topics: Animals; Arachidonic Acids; Bradykinin; Calcium; Calcium Radioisotopes; Capsaicin; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Estrenes; Ganglia, Spinal; Indomethacin; Inositol Phosphates; Ion Channels; Neurons, Afferent; Nitrobenzenes; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pyrazoles; Pyrrolidinones; Rats; Rats, Wistar; Second Messenger Systems; Signal Transduction; Sulfonamides; TRPV Cation Channels; Type C Phospholipases | 2004 |
Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Butanols; Capsaicin; Cyclooxygenase Inhibitors; Dihydroergotamine; Diphenhydramine; Diterpenes; Domperidone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Indomethacin; Malates; Methysergide; Metoclopramide; Migraine Disorders; Ondansetron; Piperidines; Ruthenium Red; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews; Sumatriptan; Time Factors; Tropanes; Vomiting | 2005 |
Effect of moxibustion at acupoints Ren-12 (Zhongwan), St-25 (Tianshu), and St-36 (Zuzanli) in the prevention of gastric lesions induced by indomethacin in Wistar rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Gastric Mucosa; Indomethacin; Male; Moxibustion; Rats; Rats, Wistar; Stomach Diseases | 2005 |
Role of sensory neuron in reduction of endotoxin-induced hypotension in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Hypotension; Iloprost; Indomethacin; Interleukin-16; Lung; Neurons, Afferent; Nitric Oxide Synthase; Prospective Studies; Rats; Rats, Wistar; Reference Values; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2005 |
Characteristics of propofol-evoked vascular pain in anaesthetized rats.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Animals; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Electromyography; Indomethacin; Injections, Intra-Arterial; Male; Muscle, Skeletal; Pain; Procaine; Propofol; Rats; Rats, Sprague-Dawley; Reflex | 2005 |
Anti-inflammatory, antinociceptive, and gastric effects of Hypericum perforatum in rats.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Drug Evaluation, Preclinical; Edema; Electroshock; Etodolac; Fluoxetine; Gastric Acid; Gastric Mucosa; Hot Temperature; Hypericum; Indomethacin; Pain; Peritonitis; Plant Extracts; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Stomach Ulcer | 2005 |
Mechanisms for modulation of mouse gastrointestinal motility by proteinase-activated receptor (PAR)-1 and -2 in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Calcium Channel Blockers; Capsaicin; Female; Gastrointestinal Motility; In Vitro Techniques; Indomethacin; Intestines; Isometric Contraction; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Relaxation; Neurons, Afferent; Oligopeptides; Potassium Channels; Prostaglandins; Receptor, PAR-1; Receptor, PAR-2; Reverse Transcriptase Polymerase Chain Reaction; Stomach | 2006 |
Importance of the pineal gland, endogenous prostaglandins and sensory nerves in the gastroprotective actions of central and peripheral melatonin against stress-induced damage.
Topics: Administration, Topical; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cerebral Ventricles; Cyclooxygenase 1; Cyclooxygenase 2; Gastrins; Immersion; Indomethacin; Melatonin; Neurons, Afferent; Pineal Gland; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Regional Blood Flow; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Psychological; Tryptophan | 2005 |
Gastric HCO3- secretion induced by mucosal acidification: different mechanisms depending on acid concentration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2005 |
Gastroprotective action of glucocorticoid hormones in rats with desensitization of capsaicin-sensitive sensory neurons.
Topics: Adrenalectomy; Animals; Blood Glucose; Capsaicin; Dose-Response Relationship, Drug; Drug Tolerance; Fasting; Gastric Mucosa; Glucocorticoids; Indomethacin; Injections, Subcutaneous; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Stomach Diseases; Time Factors | 2005 |
Stimulation by bradykinin of HCO3- secretion in rat gastroduodenal mucosa.
Topics: Animals; Bicarbonates; Bradykinin; Bradykinin B2 Receptor Antagonists; Capsaicin; Duodenum; Enzyme Inhibitors; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Sprague-Dawley | 2006 |
Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.
Topics: Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Oleic Acids; Rats; Rats, Wistar; Receptors, Cannabinoid; TRPV Cation Channels; Vasodilator Agents | 2006 |
Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Asthma; Blood Pressure; Bradykinin; Capsaicin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Guinea Pigs; Heart Rate; Indomethacin; Lung; Nerve Fibers, Unmyelinated; Prostaglandins; Respiratory Hypersensitivity; Substance P | 2006 |
Both endothelium and afferent nerve endings play a role in acetylcholine-induced renal vasodilation.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Female; Glycyrrhetinic Acid; Indomethacin; Male; Nerve Endings; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroarginine; Octoxynol; Rats; Rats, Wistar; Renal Circulation; Second Messenger Systems; Triazines; Triazoles; Vasodilator Agents | 2006 |
Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs.
Topics: Animals; Capsaicin; Citric Acid; Cough; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Diterpenes; Guinea Pigs; Indomethacin; Inflammation; Isoquinolines; Male; Neurons, Afferent; Protein Kinase C; Protein Kinase Inhibitors; Receptor, PAR-2; Saline Solution, Hypertonic; Sulfonamides; TRPV Cation Channels; Trypsin | 2006 |
Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked bradypneic reflex in anesthetized rats.
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Apyrase; Arachidonic Acid; Capsaicin; Cyclooxygenase Inhibitors; Hydrogen Peroxide; Hyperventilation; Hypoventilation; Indomethacin; Lipoxygenase Inhibitors; Male; Oxidants; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reflex; Respiratory Mechanics; TRPV Cation Channels | 2006 |
Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Acetamides; Animals; Calcium; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Histamine H2 Antagonists; Humans; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Piperidines; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Stomach; Stomach Diseases; TRPV Cation Channels | 2006 |
Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Atropine; Bronchi; Bronchodilator Agents; Capsaicin; Cholinergic Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histamine; Humans; In Vitro Techniques; Indomethacin; Leukotriene D4; Molecular Structure; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Peptides; Potassium Channels, Calcium-Activated; Propranolol; Prostaglandin D2; TRPV Cation Channels; Vasodilator Agents | 2007 |
Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats.
Topics: Animals; Antithrombins; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Disease Models, Animal; Endocannabinoids; Endotoxins; Ganglia, Spinal; Gene Expression Regulation; Hypotension; Indoles; Indomethacin; Lung; Male; Neurons, Afferent; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Peptide Fragments; Polyunsaturated Alkamides; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; RNA, Messenger; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2006 |
Prostaglandins, capsaicin-sensitive sensory nerves and neutrophil infiltration, but not nitric oxide, contribute to cold restraint stress-induced gastric adaptation in rats.
Topics: Acclimatization; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cold Temperature; Dinoprostone; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Prostaglandins; Rats; Rats, Wistar; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Physiological; Thermosensing | 2006 |
Gastric microcirculation as target of gastroprotective action of glucocorticoid hormones in rats with desensitization of capsaicin-sensitive sensory neurons.
Topics: Adrenalectomy; Animals; Capsaicin; Gastric Mucosa; Glucocorticoids; Indomethacin; Male; Microcirculation; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2006 |
Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acetamides; Animals; Anti-Ulcer Agents; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclooxygenase Inhibitors; Disease Models, Animal; Endocannabinoids; Famotidine; Ganglia, Spinal; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Male; Neurons, Afferent; Neutrophil Activation; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 2007 |
[Compensatory gastroprotective action of glucocorticoid hormones in the rats with ablation of capsaicin-sensitive neurons].
Topics: Adrenalectomy; Animals; Capsaicin; Corticosterone; Gastric Mucosa; Indomethacin; Male; Neurons; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2006 |
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.
Topics: Alkaloids; Ammonia; Animals; Armoracia; Aspirin; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Food Preservatives; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isothiocyanates; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Rats; Rats, Sprague-Dawley; Ruthenium Red; Structure-Activity Relationship | 2007 |
Atrial natriuretic peptide reduces ischemia/reperfusion-induced spinal cord injury in rats by enhancing sensory neuron activation.
Topics: 6-Ketoprostaglandin F1 alpha; Anilides; Animals; Atrial Natriuretic Factor; Calcitonin Gene-Related Peptide; Capsaicin; Carbazoles; Cells, Cultured; Cinnamates; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Indomethacin; Male; Neurons, Afferent; Peroxidase; Psychomotor Performance; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spinal Cord; Spinal Cord Diseases; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2007 |
[The effects of desensitization of capsaicin-sensitive neurons on the blood flow in microvessels of the rat gastric serous muscular membrane with normal and insufficient contents of glucocorticoids].
Topics: Adrenalectomy; Animals; Blood Flow Velocity; Capsaicin; Corticosterone; Glucocorticoids; Indomethacin; Male; Microcirculation; Neurons; Rats; Rats, Sprague-Dawley; Serous Membrane; Stomach | 2006 |
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
Topics: Animals; Aorta, Abdominal; Apamin; Arachidonic Acids; Benzamides; Calcitonin Gene-Related Peptide; Camphanes; Cannabinoid Receptor Modulators; Capsaicin; Carbamates; Charybdotoxin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Isoindoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sulfonamides; Vasodilation | 2007 |
Effects of the selective prostacyclin receptor antagonist RO3244019 on the micturition reflex in rats.
Topics: Animals; Capsaicin; Disease Models, Animal; Female; Indomethacin; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Reference Values; Reflex; Sensitivity and Specificity; Urination; Urodynamics | 2007 |
Quebrachitol-induced gastroprotection against acute gastric lesions: role of prostaglandins, nitric oxide and K+ ATP channels.
Topics: Animals; Arginine; Capsaicin; Diazoxide; Dose-Response Relationship, Drug; Ethanol; Glyburide; Indomethacin; Inositol; KATP Channels; Male; Mice; Misoprostol; Molecular Structure; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phytotherapy; Prostaglandins; Stomach Ulcer | 2008 |
Reactive oxygen species mediate detrusor overactivity via sensitization of afferent pathway in the bladder of anaesthetized rats.
Topics: Afferent Pathways; Animals; Antioxidants; Capsaicin; Catalase; Cyclooxygenase Inhibitors; Deferoxamine; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Hydrogen Peroxide; Indomethacin; Ketoprofen; Prostaglandins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sensory System Agents; Siderophores; Superoxide Dismutase; Thiourea; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2008 |
A reactive oxygen species-mediated component in neurogenic vasodilatation.
Topics: Acetophenones; Animals; Antioxidants; Blood Flow Velocity; Blood Vessels; Calcitonin Gene-Related Peptide; Capsaicin; Catalase; Ear; Indomethacin; Laser-Doppler Flowmetry; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Reactive Oxygen Species; Receptors, Neurokinin-1; Regional Blood Flow; Superoxide Dismutase; Tetraethylammonium; Time Factors; TRPV Cation Channels; Vasodilation; Vasodilator Agents | 2008 |
Role of capsaicin-sensitive afferent neurons in receptive relaxation induced by gastric distension in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds; Calcitonin Gene-Related Peptide; Caproates; Capsaicin; Catheterization; Enzyme Inhibitors; Indomethacin; Male; Muscle Relaxation; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandins; Rats; Rats, Sprague-Dawley; Stomach; Vagotomy | 2007 |
Counteracting effect of papaverine on morphine inhibition of gastrointestinal transit in mice.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Constipation; Dexamethasone; Enzyme Inhibitors; Gastrointestinal Transit; Glucocorticoids; Humans; Indomethacin; Male; Mice; Morphine; NG-Nitroarginine Methyl Ester; Papaverine; Sensory System Agents | 2008 |
In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI.
Topics: Androstadienes; Animals; Anti-Inflammatory Agents; Aza Compounds; Benzamides; Bronchoalveolar Lavage Fluid; Budesonide; Capsaicin; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Drug Evaluation, Preclinical; Indomethacin; Lung; Magnetic Resonance Imaging; Male; Mast Cells; Naphthoquinones; ortho-Aminobenzoates; p-Methoxy-N-methylphenethylamine; Proteins; Pulmonary Edema; Rats; Rats, Inbred BN; Respiratory System Agents; Time Factors; Wortmannin | 2008 |
Gastroprotective mechanisms of centipedic acid, a natural diterpene from Egletes viscosa LESS.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Asteraceae; Capsaicin; Central Nervous System Depressants; Diterpenes; Drug Interactions; Enzyme Inhibitors; Ethanol; Fatty Acids, Unsaturated; Free Radical Scavengers; Furans; Gastric Mucosa; Glyburide; Hypoglycemic Agents; Indomethacin; Male; Mice; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Oxidative Stress; Pylorus; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances | 2008 |
[Effects of desensitization of capsaicin-sensitive afferent neurons on gastric microcirculation in rats depend on the blood glucocorticoid hormone level].
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Capillary Permeability; Capsaicin; Gastric Mucosa; Glucocorticoids; Indomethacin; Male; Microcirculation; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Stomach | 2008 |
Activation of sensory neurons reduces ischemia/reperfusion-induced acute renal injury in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capillary Permeability; Capsaicin; Chemokine CCL2; Denervation; Immunohistochemistry; Indomethacin; Kidney; Kidney Diseases; Male; Peptide Fragments; Peroxidase; Rats; Rats, Wistar; Renal Circulation; Reperfusion Injury; Sensory Receptor Cells; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2009 |
Inflammatory mediators released following application of irritants on the rat injured incisors. The effect of treatment with anti-inflammatory drugs.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Capsaicin; Celecoxib; Dexamethasone; Dinoprostone; Endotoxins; Incisor; Indomethacin; Inflammation Mediators; Irritants; Morphine; Nerve Growth Factor; Pyrazoles; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sulfonamides | 2009 |
PGE(2)-induced lasting nociception to heat: evidences for a selective involvement of A-delta fibres in the hyperpathic component of hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Dimethyl Sulfoxide; Dinoprostone; Hot Temperature; Hyperalgesia; Indomethacin; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Nociceptors; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar | 2010 |
The effects of desensitization of capsaicin-sensitive afferent neurons on the microcirculation in the stomach in rats depend on the blood glucocorticoid hormone level.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Capillary Permeability; Capsaicin; Gastric Mucosa; Glucocorticoids; Indomethacin; Male; Microcirculation; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Stomach | 2009 |
Behavioral and urological evaluation of a testicular pain model.
Topics: Acetic Acid; Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Indomethacin; Male; Nerve Fibers, Unmyelinated; Neurons, Afferent; Pain; Prostatitis; Rats; Rats, Wistar; Testis; Urinary Bladder; Urinary Bladder, Overactive | 2010 |
Stimulation by sparkling water of gastroduodenal HCO3- secretion in rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Afferent Pathways; Amiloride; Animals; Bicarbonates; Capsaicin; Carbonated Beverages; Dinoprostone; Duodenum; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Water | 2009 |
Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice.
Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Antioxidants; Capsaicin; Disease Models, Animal; Diterpenes; Ethanol; Gastric Mucosa; Glyburide; Indomethacin; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Extracts; Plant Leaves; Plectranthus; Quinones; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbiturates | 2010 |
Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats.
Topics: Acetylcysteine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Ankyrins; Antioxidants; Apyrase; Blood Pressure; Calcium Channels; Capsaicin; Cyclooxygenase Inhibitors; Heart Rate; Indomethacin; Inhalation Exposure; Lung; Male; Neurons, Afferent; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reflex; Respiration, Artificial; Respiratory Mechanics; Sensory System Agents; Signal Transduction; Smoke; Smoking; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels; Vagus Nerve | 2010 |
Probiotic bacteria Escherichia coli strain Nissle 1917 attenuates acute gastric lesions induced by stress.
Topics: Animals; Capsaicin; Cyclooxygenase 2; Disease Models, Animal; Escherichia coli; Gastric Mucosa; Ghrelin; HSP70 Heat-Shock Proteins; Immersion; Indomethacin; Interleukin-1beta; Nitric Oxide Synthase; PPAR gamma; Probiotics; Rats; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 2009 |
TRPA1 receptor induced relaxation of the human urethra involves TRPV1 and cannabinoid receptor mediated signals, and cyclooxygenase activation.
Topics: Acrolein; Analysis of Variance; Arginine; Calcium Channels; Capsaicin; Cyclohexanols; Female; Humans; Immunohistochemistry; Indomethacin; Isothiocyanates; Male; Middle Aged; Nerve Tissue Proteins; Receptors, Cannabinoid; Signal Transduction; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Urethra | 2010 |
Stimulation of duodenal HCO₃⁻ secretion by hydrogen sulphide in rats: relation to prostaglandins, nitric oxide and sensory neurones.
Topics: Air Pollutants; Alkynes; Animals; Bicarbonates; Capsaicin; Dinoprostone; Duodenum; Enzyme Inhibitors; Glyburide; Glycine; Hydrogen Sulfide; Hypoglycemic Agents; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Sulfides | 2011 |
Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity.
Topics: Animals; Aorta, Thoracic; Arachidonic Acids; Caffeine; Capsaicin; Chloride Channels; Endocannabinoids; Endothelium, Vascular; Ethanolamines; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Nitric Oxide; Oleic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; Vasodilation | 2010 |
Phenotypes and peripheral mechanisms underlying inflammatory pain-related behaviors induced by BmK I, a modulator of sodium channels.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bupivacaine; Capsaicin; Ganglia, Spinal; Indomethacin; Inflammation; Male; Morphine; Neurons; Pain; Pain Measurement; Patch-Clamp Techniques; Phenotype; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Sodium Channel Blockers | 2010 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones | 2012 |
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Arterioles; Benzamides; Benzoxazines; Blood Pressure; Caproates; Capsaicin; Carbamates; Dose-Response Relationship, Drug; Endocannabinoids; Flavanones; Immunohistochemistry; In Vitro Techniques; Indomethacin; Morpholines; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Polyunsaturated Alkamides; Rats | 2012 |
Gastroprotective potential of frutalin, a D-galactose binding lectin, against ethanol-induced gastric lesions.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Biomarkers; Capsaicin; Cimetidine; Ethanol; Galactose; Galectins; Gastric Mucosa; Glutathione; Glyburide; Indomethacin; Male; Malondialdehyde; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phytotherapy; Plant Extracts; Stomach Ulcer | 2012 |
Involvement of perivascular nerves and transient receptor potential vanilloid 1 (TRPV1) in vascular responses to histamine in rat mesenteric resistance arteries.
Topics: Acetamides; Animals; Benzoquinones; Capsaicin; Endothelium, Vascular; Heptanoic Acids; Histamine; Indomethacin; Male; Mesenteric Arteries; Methoxamine; Piperidines; Procaine; Prostaglandins; Pyridines; Rats; Rats, Wistar; Receptors, Histamine H2; Ruthenium Red; Tetrodotoxin; Thromboxane A2; TRPV Cation Channels; Vasoconstriction; Vasodilation | 2012 |
Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amidohydrolases; Animals; Anisoles; Apamin; Arachidonic Acids; Benzamides; Benzyl Compounds; Cannabinoid Receptor Antagonists; Capsaicin; Carbamates; Charybdotoxin; Cyclohexanes; Endocannabinoids; Endothelium, Vascular; Imidazoles; Indoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Epoprostenol; Tetraethylammonium; TRPV Cation Channels; Vasodilation | 2012 |
Mechanisms underlying the augmentation of phenylbiguanide and capsaicin induced cardiorespiratory reflexes by Mesobuthus tamulus venom.
Topics: Animals; Aprotinin; Biguanides; Capsaicin; Drug Synergism; Female; Hemodynamics; Indomethacin; Methylene Blue; Phosphodiesterase 5 Inhibitors; Pulmonary Edema; Rats; Reflex; Respiration; Scorpion Venoms | 2012 |
Exacerbation of nonsteroidal anti-inflammatory drug-induced small intestinal lesions by antisecretory drugs in rats: the role of intestinal motility.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capsaicin; Dose-Response Relationship, Drug; Gastrointestinal Motility; Histamine H2 Antagonists; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Proton Pump Inhibitors; Rats; Rats, Wistar; Sensory Receptor Cells; Stomach Ulcer | 2012 |
The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves.
Topics: Animals; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Cyclooxygenase Inhibitors; Endocannabinoids; Female; Guinea Pigs; Indomethacin; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Polyunsaturated Alkamides; Prostaglandins; Sensory Receptor Cells; Sensory System Agents; TRPV Cation Channels | 2013 |
Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats.
Topics: Acetanilides; Acetylcysteine; Animals; Antioxidants; Apnea; Calcium Channels; Capsaicin; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Indomethacin; Laryngeal Nerves; Larynx; Neurons, Afferent; Purines; Rats; Reactive Oxygen Species; Smoking; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels | 2013 |
Hydrogen sulfide mediated inhibitory neurotransmission to the pig bladder neck: role of KATP channels, sensory nerves and calcium signaling.
Topics: Acetanilides; Acrylamides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcitonin Gene-Related Peptide; Calcium Signaling; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Glyburide; Guanylate Cyclase; Hydrogen Sulfide; Indomethacin; KATP Channels; Morpholines; Muscle, Smooth; Organothiophosphorus Compounds; Phenylephrine; Pituitary Adenylate Cyclase-Activating Polypeptide; Purines; Pyrazoles; Sensory Receptor Cells; Swine; Synaptic Transmission; Urinary Bladder | 2013 |
H2S-induced HCO3- secretion in the rat stomach--involvement of nitric oxide, prostaglandins, and capsaicin-sensitive sensory neurons.
Topics: Animals; Bicarbonates; Capsaicin; Gastric Mucosa; Hydrogen Sulfide; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Stomach; Sulfides | 2015 |
Peripheral neurokinin-1 receptors contribute to kaolin-induced acute monoarthritis in rats.
Topics: Animals; Animals, Newborn; Antidiarrheals; Arthritis; Capsaicin; Cytokines; Disease Models, Animal; Edema; Enzyme Inhibitors; Hyperalgesia; Indomethacin; Kaolin; Knee Joint; Male; Pain Measurement; Peroxidase; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Synovial Fluid | 2015 |
Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: Mechanisms involved in the gastroprotective activity.
Topics: Animals; Antioxidants; Capsaicin; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Ericales; Ethanol; Female; Flavonoids; Gastrointestinal Motility; Glyburide; Histamine; Indomethacin; Male; Mice; Mucus; Naloxone; NG-Nitroarginine Methyl Ester; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Protective Agents; Stomach Ulcer; Water; Yohimbine | 2017 |
Mechanisms of curcumin-induced gastroprotection against ethanol-induced gastric mucosal lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; CDX2 Transcription Factor; Curcumin; Cyclooxygenase 2 Inhibitors; Denervation; Down-Regulation; Ethanol; Female; Gastric Mucosa; Gastrins; Gene Expression; Heme Oxygenase (Decyclizing); Hypoxia-Inducible Factor 1, alpha Subunit; Indomethacin; Lactones; Male; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; RNA, Messenger; Stomach Diseases; Sulfones; Superoxide Dismutase; TRPV Cation Channels; Up-Regulation | 2018 |
Vulnerability of gastric and small intestinal mucosa to ulcerogenic action of indomethacin in C57/BL6/J mice and transient receptor potential channel vanilloid type 1 knockout mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptic Ulcer; Stomach Ulcer; Time Factors; TRPV Cation Channels | 2018 |
Proton Pump Inhibitors Prevent Gastric Antral Ulcers Induced by NSAIDs via Activation of Capsaicin-Sensitive Afferent Nerves in Mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Disease Models, Animal; Gastric Emptying; Gastric Juice; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Lansoprazole; Male; Mice; Neurons, Afferent; Omeprazole; Proton Pump Inhibitors; Pyloric Antrum; Stomach Ulcer | 2020 |