capsaicin has been researched along with hydrochloric acid in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.00) | 18.7374 |
| 1990's | 24 (40.00) | 18.2507 |
| 2000's | 25 (41.67) | 29.6817 |
| 2010's | 8 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arvier, PT; Chahl, LA; Ladd, RJ | 1 |
| Guth, PH; Li, DS; Quintero, E; Raybould, HE | 1 |
| Fändriks, L; Hamlet, A; Jönson, C | 1 |
| Matsumoto, J; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Amann, R; Holzer, P; Lippe, IT | 1 |
| Abelli, L; Amenta, F; Borsini, F; Evangelista, S; Geppetti, P; Maggi, CA; Manzini, S; Santicioli, P; Somma, V; Theodorsson-Norheim, E | 1 |
| Mózsik, G; Szolcsányi, J | 1 |
| Heinemann, A; Holzer, P; Jocic, M; Wachter, C | 1 |
| Holzer-Petsche, U; Rordorf-Nikolić, T | 1 |
| Malagelada, JR; Santos, J; Saperas, E | 1 |
| Ohuchi, T; Okabe, S; Takeuchi, K | 1 |
| Ohuchi, T; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Hölzer, HH; Raybould, HE | 1 |
| Leung, FW | 1 |
| Basu, BK; Holitzner, CA; Morris, GP; Williamson, TE | 1 |
| Lam, K; Leung, FW; Leung, JW; Seno, K | 1 |
| Pécová, R; Tatár, M | 1 |
| Hällgren, A; Hellström, PM; Lördal, M; Nylander, O | 1 |
| Bonnevier, JL; Hogan, WJ; Kusano, M; Lang, IM; Massey, BT; Shaker, R | 1 |
| Hatakeyama, Y; Ohtsuka, M; Shimomura, K; Tomoi, M | 1 |
| Abdel Salam, OM; Mózsik, G; Szolcsányi, J | 1 |
| Heinemann, A; Holzer, P; Jocic, M; Pabst, MA; Schöninkle, E; Schuligoi, R | 1 |
| Iwata, F; Lam, K; Leung, FW; Leung, JW; Seno, K | 1 |
| Fallone, CA; MacNaughton, WK; Morris, GP; Pringle, GC | 1 |
| Ishikawa, T; Sant'Ambrogio, FB; Sant'Ambrogio, G; Sekizawa, S | 1 |
| Lu, YX; Owyang, C | 1 |
| Ahlman, H; Jodal, M; Lundgren, O; Svensson, M; Timar Peregrin, A | 1 |
| Flemström, G; Hellgren, S; Nylander, O | 1 |
| Gyires, K; Rónai, AZ | 1 |
| Itoh, M; Iwata, F; Kao, J; Leung, FW; Leung, JW; Seno, K | 2 |
| Advenier, C; D'Agostino, B; De Rosa, G; Filippelli, W; Gallelli, L; Marrocco, G; Rossi, F | 1 |
| Holzer, P; Lippe, IT; Pabst, MA; Schemann, M; Schicho, R | 1 |
| Kato, S; Matsumoto, M; Nakashima, M; Ogawa, Y; Takeeda, M; Takeuchi, K | 1 |
| Iwata, F; Leung, FW; Leung, JW; Seno, K | 1 |
| Bielefeldt, K; Gebhart, GF; Kang, YM; Lamb, K | 1 |
| Belai, A; Horie, S; Michael, GJ; Murayama, T; Priestley, JV; Uchida, M; Watanabe, K; Yamamoto, H | 1 |
| Aihara, E; Aoi, M; Nakashima, M; Takeuchi, K | 1 |
| Cadiou, H; Jones, NG; McMahon, SB; McNaughton, P; Slater, R | 1 |
| Bartos, V; Brozmanova, M; Kollarik, M; Plank, L; Plevkova, J; Revallo, M; Tatar, M; Varechova, S | 1 |
| Aihara, E; Hayashi, M; Sasaki, Y; Takeuchi, K | 1 |
| Matsuda, H; Nagatomo, A; Ochi, M; Yoshikawa, M | 1 |
| Chapple, C; Chess-Williams, R; Daly, D; Grundy, D; Rong, W | 1 |
| Farber, JP; Foreman, RD; Qin, C | 1 |
| Führer, M; Hammer, J | 1 |
| Amagase, K; Hayashi, S; Komatsu, Y; Kotani, T; Murashima, Y; Nakagiri, A; Takeuchi, K | 1 |
| Ichinose, M; Ito, T; Kimura, H; Oka, M; Shimizu, Y; Tsuruo, Y; Ueda, K; Ueyama, T; Yoshida, K | 1 |
| Chen, CF; Hsieh, HT; Lai, IR; Lee, JM; Lin, BR; Yu, LC | 1 |
| Chancellor, MB; de Groat, WC; Erickson, KA; Erickson, VL; Hayashi, Y; Kirimoto, T; Nakano, K; Takimoto, K; Yoshimura, N | 1 |
| Banerjee, B; Lehmann, A; Medda, BK; Peles, S; Sengupta, JN; Shaker, R; Zhang, Z | 1 |
| Behar, J; Biancani, P; Cao, W; Cheng, L; de la Monte, S; Harnett, KM; Hong, J; Ma, J; Tong, M | 1 |
| Andresen, T; Arendt-Nielsen, L; Brock, C; Drewes, AM; Frøkjaer, JB; Gale, J; Olesen, AE | 1 |
| Burcher, E; Liu, L; Mansfield, KJ; Sadananda, P; Shang, F | 1 |
| Chen, CL; Liu, TT; Yi, CH | 1 |
| Nylander, O; Sjöblom, M; Sommansson, A; Wan Saudi, WS | 1 |
| Chen, CL; Hung, JS; Lei, WY; Liu, TT; Orr, WC; Yi, CH | 1 |
| Chung, MK; Diatchenko, L; Joseph, J; Ro, JY; Wang, S | 1 |
| Garami, A; Ivic, I; Koller, A; Pakai, E; Pinter, E; Rumbus, Z; Solymar, M | 1 |
| Hu, Y; Yu, S; Yu, X | 1 |
| Barker, AJ; Bennett, NC; Debus, KY; Eigenbrod, O; Hart, DW; Katandukila, JV; Lewin, GR; Lutermann, H; Mgode, G; Omerbašić, D; Park, TJ; Reznick, J; Sánchez-Carranza, O; Zhong, W | 1 |
60 other study(ies) available for capsaicin and hydrochloric acid
| Article | Year |
|---|---|
Modification by capsaicin and compound 48/80 of dye leakage induced by irritants in the rat.
Topics: Adenosine Triphosphate; Animals; Azo Compounds; Bradykinin; Capsaicin; Edema; Evans Blue; Fatty Acids, Unsaturated; Formaldehyde; Histamine; Hydrochloric Acid; Male; Models, Biological; p-Methoxy-N-methylphenethylamine; Potassium Chloride; Prostaglandins E; Rats; Serotonin; Skin | 1977 |
Calcitonin gene-related peptide mediates the gastric hyperemic response to acid back-diffusion.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Diffusion; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Calcitonin; Receptors, Cell Surface; Regional Blood Flow | 1992 |
The mediation of increased duodenal alkaline secretion in response to 10 mM HCl in the anaesthetized rat. Support for the involvement of capsaicin-sensitive nerve elements.
Topics: Animals; Bicarbonates; Capsaicin; Dinoprostone; Duodenum; Hydrochloric Acid; Intestinal Mucosa; Lidocaine; Male; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Vagotomy; Vagus Nerve | 1992 |
Role of capsaicin-sensitive afferent neurons in mucosal blood flow response of rat stomach induced by mild irritants.
Topics: Animals; Capsaicin; Denervation; Gastric Acidity Determination; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Irritants; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Regional Blood Flow; Sodium Chloride | 1992 |
Participation of capsaicin-sensitive afferent neurons in gastric motor inhibition caused by laparotomy and intraperitoneal acid.
Topics: Animals; Blood Pressure; Capsaicin; Female; Gastrointestinal Motility; Guanethidine; Hydrochloric Acid; Injections, Intraperitoneal; Laparotomy; Male; Motor Neurons; Neurons, Afferent; Rats; Rats, Inbred Strains; Stomach | 1992 |
Cutaneous lesions in capsaicin-pretreated rats. A trophic role of capsaicin-sensitive afferents?
Topics: Animals; Animals, Newborn; Behavior, Animal; Capillary Permeability; Capsaicin; Female; Hair; Hydrochloric Acid; Male; Neurons, Afferent; Neuropeptides; Rats; Skin; Skin Diseases; Skin Ulcer; Substance P; Tachykinins | 1987 |
Effects of capsaicin on the development of gastric mucosal damage by different necrotizing agents and of gastric cytoprotection by PGI2 atropine and cimetidine on rats.
Topics: Animals; Atropine; Capsaicin; Cimetidine; Epoprostenol; Ethanol; Female; Gastric Mucosa; Hydrochloric Acid; Male; Premedication; Rats; Sodium Chloride; Sodium Hydroxide; Stomach Ulcer | 1984 |
Visceral vasodilatation and somatic vasoconstriction evoked by acid challenge of the rat gastric mucosa: diversity of mechanisms.
Topics: Animals; Capsaicin; Denervation; Female; Femoral Artery; Gastric Mucosa; Hemodynamics; Hexamethonium; Hydrochloric Acid; Perfusion; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach; Vasoconstriction; Vasodilation; Viscera | 1995 |
Central versus peripheral site of action of the tachykinin NK1-antagonist RP 67580 in inhibiting chemonociception.
Topics: Analgesics; Animals; Blood Pressure; Blood-Brain Barrier; Capsaicin; Female; Hydrochloric Acid; Indoles; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Stereoisomerism; Substance P | 1995 |
Role of vagal and splanchnic capsaicin-sensitive afferents in enterogastric inhibition of acid secretion in rats.
Topics: Animals; Capsaicin; Ganglionectomy; Gastric Acid; Hydrochloric Acid; Intestines; Male; Neurons, Afferent; Pentagastrin; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Stomach; Thyrotropin-Releasing Hormone; Vagotomy; Vagus Nerve | 1995 |
Capsaicin-sensitive sensory neurons in healing gastric lesions induced by HCl in rats.
Topics: Animals; Capsaicin; Denervation; Gastric Mucosa; Hydrochloric Acid; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach Diseases; Wound Healing | 1994 |
The role of capsaicin-sensitive sensory neurons in healing of HCl-induced gastric mucosal lesions in rats.
Topics: Animals; Capsaicin; Gastric Mucosa; Hydrochloric Acid; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Stomach Diseases; Wound Healing | 1994 |
Duodenal acid-induced inhibition of gastric motility and emptying in rats.
Topics: Animals; Capsaicin; Duodenum; Gastric Emptying; Gastrointestinal Motility; Hydrochloric Acid; Male; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sympathectomy; Vagotomy | 1993 |
Primary sensory nerves mediate in part the protective mesenteric hyperemia after intraduodenal acidification in rats.
Topics: Animals; Capsaicin; Duodenum; Hydrochloric Acid; Hyperemia; Lidocaine; Male; Mesenteric Artery, Superior; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1993 |
Mucosal secretion and cytoprotection of the rat gastric mucosa.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Acidity Determination; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Mannitol; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sucralfate | 1993 |
Aging impairs afferent nerve function in rat intestine. Reduction of mesenteric hyperemia induced by intraduodenal capsaicin and acid.
Topics: Afferent Pathways; Aging; Animals; Capsaicin; Duodenum; Hydrochloric Acid; Hyperemia; Intestinal Mucosa; Male; Mesenteric Artery, Superior; Rats | 1996 |
[The effect of experimental gastroesophageal reflux on the cough reflex in anesthetized cats].
Topics: Anesthesia; Animals; Capsaicin; Cats; Cough; Esophagus; Female; Gastroesophageal Reflux; Hydrochloric Acid; Male; Muscle Contraction; Physical Stimulation; Reflex; Sodium Chloride | 1996 |
Tachykinins increase vascular permeability in the gastrointestinal tract of the rat.
Topics: Animals; Capsaicin; Digestive System; Dose-Response Relationship, Drug; Duodenum; Hydrochloric Acid; Male; Neurokinin A; Permeability; Rats; Rats, Sprague-Dawley; Stomach; Tachykinins | 1996 |
Initiation of esophageal secondary peristalsis by slow fluid infusion in the opossum: effect of hydrochloric acid.
Topics: Animals; Atropine; Capsaicin; Esophagostomy; Esophagus; Female; Fluoroscopy; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Opossums; Peristalsis; Physical Stimulation; Solutions; Television; Tetrodotoxin; Vagotomy | 1996 |
Implication of sensory neurons in the diverse mechanisms of adaptive cytoprotection in the rat stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Capsaicin; Cell Differentiation; Cyclooxygenase Inhibitors; Denervation; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Stomach | 1996 |
The indomethacin-induced gastric mucosal damage in rats. Effect of gastric acid, acid inhibition, capsaicin-type agents and prostacyclin.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diterpenes; Epoprostenol; Female; Gastric Acid; Gastric Mucosa; Histamine; Hydrochloric Acid; Indomethacin; Isoproterenol; Laser-Doppler Flowmetry; Male; Microcirculation; Neurotoxins; Pentagastrin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach Ulcer; Vasodilator Agents | 1997 |
Gastric acid-evoked c-fos messenger RNA expression in rat brainstem is signaled by capsaicin-resistant vagal afferents.
Topics: Afferent Pathways; Animals; Brain Stem; Capsaicin; Female; Gastric Acid; Gastric Mucosa; Genes, fos; Hydrochloric Acid; Instillation, Drug; Morphine; Naloxone; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Skin; Spinal Cord; Transcription, Genetic; Vagus Nerve | 1998 |
Mechanism of acid-induced mesenteric hyperemia in rats.
Topics: Animals; Blood Pressure; Capsaicin; Duodenum; Hydrochloric Acid; Hyperemia; Laser-Doppler Flowmetry; Male; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Ruthenium Red | 1998 |
Gastric cytoprotection is secondary to increased mucosal fluid secretion: a study of six cytoprotective agents in the rat.
Topics: Animals; Anti-Ulcer Agents; Capsaicin; Cytoprotection; Cytotoxins; Dinoprostone; Ethylmaleimide; Female; Gastric Mucosa; Hydrochloric Acid; Male; Misoprostol; Nicotine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Rioprostil | 1998 |
Vagal esophageal receptors in anesthetized dogs: mechanical and chemical responsiveness.
Topics: Acetylcholine; Afferent Pathways; Anesthesia, General; Animals; Capsaicin; Chemoreceptor Cells; Dogs; Esophagus; Female; Hydrochloric Acid; Male; Pepsin A; Temperature; Vagus Nerve | 1999 |
Duodenal acid-induced gastric relaxation is mediated by multiple pathways.
Topics: Acids; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Gastrointestinal Motility; Hormone Antagonists; Hydrochloric Acid; Immune Sera; Male; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Secretin; Serotonin Antagonists; Vagotomy; Vagus Nerve | 1999 |
The effects on net fluid transport of noxious stimulation of jejunal mucosa in anaesthetized rats.
Topics: Anesthesia; Animals; Atropine; Axons; Calcium Channel Blockers; Calcium Channels; Capsaicin; Enteric Nervous System; Enterochromaffin Cells; Glucose; Granisetron; Hexamethonium; Hydrochloric Acid; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Muscarinic Antagonists; Nicotinic Antagonists; Nifedipine; Organ Preservation Solutions; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tromethamine; Water | 1999 |
Nitric oxide prevents rat duodenal contractions induced by potentially noxious agents.
Topics: Animals; Arginine; Bicarbonates; Capsaicin; Carbon Dioxide; Chromium Radioisotopes; Crosses, Genetic; Duodenum; Edetic Acid; Ethanol; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Intubation, Gastrointestinal; Male; Metabolic Clearance Rate; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 2000 |
Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.
Topics: Animals; beta-Endorphin; Brain; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach Ulcer; Vagotomy | 2001 |
Role of bradykinin in acid-induced mesenteric hyperemia and duodenal villous damage.
Topics: Animals; Blood Flow Velocity; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; Duodenum; Hydrochloric Acid; Hyperemia; Intestinal Mucosa; Male; Mesenteric Artery, Superior; Mesentery; Rats; Rats, Sprague-Dawley; Ultrasonography, Doppler, Pulsed | 2002 |
Ruthenium red-sensitive cation channels, but not calcitonin gene-related peptide or substance P-mediated mechanisms, protect duodenal villi against acid-induced damage.
Topics: Acids; Animals; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Capsaicin; Cations; Dose-Response Relationship, Drug; Duodenum; Hydrochloric Acid; Hydrogen-Ion Concentration; Intestinal Mucosa; Ion Channels; Male; Neurons, Afferent; Peptide Fragments; Rats; Rats, Sprague-Dawley; Ruthenium Red; Substance P | 2002 |
Role of tachykinins in the bronchoconstriction induced by HCl intraesophageal instillation in the rabbit.
Topics: Airway Resistance; Animals; Bronchi; Bronchoconstriction; Capsaicin; Esophagus; Glycopeptides; Hydrochloric Acid; Intubation, Gastrointestinal; Lung Compliance; Male; Neurokinin-1 Receptor Antagonists; Protease Inhibitors; Rabbits; Receptors, Neurokinin-2; Respiratory Function Tests; Stimulation, Chemical; Tachykinins | 2003 |
Capsaicin-sensitive extrinsic afferents are involved in acid-induced activation of distinct myenteric neurons in the rat stomach.
Topics: Animals; Capsaicin; Cells, Cultured; Female; Ganglionic Blockers; Gastric Mucosa; Genes, fos; Hexamethonium; Hydrochloric Acid; Immunohistochemistry; Microscopy, Confocal; Myenteric Plexus; Neural Pathways; Neurons, Afferent; Rats; Rats, Sprague-Dawley | 2003 |
Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cytoprotection; Digestive System; Epoprostenol; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Mice; Mice, Knockout; Prostaglandins; Protective Agents; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Regional Blood Flow; Stomach Diseases | 2003 |
Acid-induced mesenteric hyperemia in rats: role of CGRP, substance P, prostaglandin, adenosine, and histamine.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Hydrochloric Acid; Hyperemia; Intestinal Mucosa; Laser-Doppler Flowmetry; Male; Mesenteric Artery, Superior; Mesentery; Nerve Tissue Proteins; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Regional Blood Flow; Substance P; Vasodilator Agents | 2003 |
Gastric inflammation triggers hypersensitivity to acid in awake rats.
Topics: Animals; Capsaicin; Catheterization; Denervation; Electromyography; Gastritis; Gastrointestinal Motility; Hydrochloric Acid; Male; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Stomach; Stomach Ulcer; Vagotomy; Viscera | 2003 |
Protective role of vanilloid receptor type 1 in HCl-induced gastric mucosal lesions in rats.
Topics: Acetamides; Animals; Anti-Ulcer Agents; Capsaicin; Catechols; Diterpenes; Famotidine; Fatty Alcohols; Gastric Mucosa; Hydrochloric Acid; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Stomach Ulcer | 2004 |
Participation of prostaglandin E receptor EP4 subtype in duodenal bicarbonate secretion in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bicarbonates; Capsaicin; Dinoprostone; Drug Combinations; Duodenum; Hydrochloric Acid; Male; Methyl Ethers; Naphthalenes; Phenylbutyrates; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Verapamil | 2004 |
Acid-induced pain and its modulation in humans.
Topics: Acid Sensing Ion Channels; Administration, Cutaneous; Adult; Amiloride; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diclofenac; Female; Forearm; Hot Temperature; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Hyperalgesia; Ibuprofen; Injections, Subcutaneous; Ion Channels; Iontophoresis; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Pain; Pain Measurement; Pain Threshold; Refractory Period, Electrophysiological; Single-Blind Method; Sodium Channels; TRPV Cation Channels | 2004 |
The effect of chemical stimulation of esophageal mucosa on citric acid induced cough and specific airway resistance in guinea pig.
Topics: Airway Resistance; Animals; Capsaicin; Citric Acid; Cough; Esophagitis; Esophagus; Guinea Pigs; Hydrochloric Acid; Male; Mucous Membrane; Neurons, Afferent; Sodium Hydroxide; Stimulation, Chemical | 2005 |
Gastric HCO3- secretion induced by mucosal acidification: different mechanisms depending on acid concentration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2005 |
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.
Topics: Alkaloids; Ammonia; Animals; Armoracia; Aspirin; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Food Preservatives; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isothiocyanates; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Rats; Rats, Sprague-Dawley; Ruthenium Red; Structure-Activity Relationship | 2007 |
Bladder afferent sensitivity in wild-type and TRPV1 knockout mice.
Topics: Action Potentials; Animals; Capsaicin; Hydrochloric Acid; Male; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Pressure; Time Factors; TRPV Cation Channels; Urinary Bladder | 2007 |
Intraesophageal chemicals enhance responsiveness of upper thoracic spinal neurons to mechanical stimulation of esophagus in rats.
Topics: Animals; Bradykinin; Capsaicin; Catheterization; Esophagus; Extracellular Space; Hydrochloric Acid; Injections; Male; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord | 2008 |
Duodenal chemosensitivity and mechanosensitivity in humans during acid and ethanol perfusion.
Topics: Adult; Capsaicin; Duodenum; Ethanol; Female; Humans; Hydrochloric Acid; Male; Mechanotransduction, Cellular; Nociceptors; Physical Stimulation; Pressure; Reaction Time; Sensory Thresholds; Single-Blind Method; TRPV Cation Channels; Young Adult | 2008 |
Impairment by 5-fluorouracil of the healing of gastric lesions in rats: effect of lafutidine, a histamine H2 receptor antagonist, mediated by capsaicin-sensitive afferent neurons.
Topics: Acetamides; Animals; Antimetabolites, Antineoplastic; Capsaicin; Cell Line; Cell Movement; Cell Proliferation; Disease Models, Animal; Epithelial Cells; Fluorouracil; Gastric Mucosa; Histamine H2 Antagonists; Hydrochloric Acid; Male; Neurons, Afferent; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sensory System Agents; Stomach Diseases; Wound Healing | 2009 |
Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions.
Topics: Adaptation, Physiological; Aldehydes; Animals; Capsaicin; Cytoprotection; Denervation; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; Gastric Mucosa; Heme Oxygenase (Decyclizing); Hydrochloric Acid; Lipid Peroxidation; Macrophages; Male; NF-E2-Related Factor 2; Oxidative Stress; Protoporphyrins; Rats; Rats, Wistar; Signal Transduction; Stomach Ulcer | 2008 |
Luminal hydrochloric acid stimulates rapid transepithelial ion fluxes in rodent esophageal stratified squamous epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adolescent; Aged; Amiloride; Animals; Autonomic Pathways; Bicarbonates; Buffers; Capsaicin; Cystic Fibrosis Transmembrane Conductance Regulator; Diffusion Chambers, Culture; Epithelium; Esophagus; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Ions; Male; Middle Aged; Neurons, Afferent; Parasympathetic Nervous System; Rats; Rats, Wistar; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2008 |
Bladder hyperactivity and increased excitability of bladder afferent neurons associated with reduced expression of Kv1.4 alpha-subunit in rats with cystitis.
Topics: Animals; Capsaicin; Cystitis; Disease Models, Animal; Female; Hydrochloric Acid; Kv1.4 Potassium Channel; Nerve Fibers, Unmyelinated; Neurons, Afferent; Patch-Clamp Techniques; Protein Subunits; Rats; Rats, Sprague-Dawley; Sensory System Agents; Urinary Bladder; Urinary Bladder, Overactive | 2009 |
Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats.
Topics: Acrylamides; Afferent Pathways; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Disease; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Mechanotransduction, Cellular; Nerve Fibers; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiourea; TRPV Cation Channels; Vagus Nerve | 2009 |
HCl-activated neural and epithelial vanilloid receptors (TRPV1) in cat esophageal mucosa.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Diterpenes; Electric Stimulation; Epithelial Cells; Esophagus; Hydrochloric Acid; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Stimulation, Chemical; Submucous Plexus; Substance P; Tetrodotoxin; TRPV Cation Channels | 2009 |
Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus.
Topics: Adult; Analysis of Variance; Body Temperature; Capsaicin; Cerebral Cortex; Electric Stimulation; Electroencephalography; Esophagus; Evoked Potentials, Somatosensory; Female; Humans; Hydrochloric Acid; Hyperalgesia; Male; Middle Aged; Pain; Pain Measurement; Pain Threshold; Rectum | 2010 |
Release of ATP from rat urinary bladder mucosa: role of acid, vanilloids and stretch.
Topics: Acid Sensing Ion Channels; Adenosine Triphosphate; Animals; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Mucous Membrane; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Sodium Channels; TRPV Cation Channels; Urinary Bladder | 2009 |
Comparable effects of capsaicin-containing red pepper sauce and hydrochloric acid on secondary peristalsis in humans.
Topics: Adult; Capsaicin; Capsicum; Esophagus; Female; Heartburn; Humans; Hydrochloric Acid; Male; Manometry; Peristalsis; Young Adult | 2013 |
The ethanol-induced stimulation of rat duodenal mucosal bicarbonate secretion in vivo is critically dependent on luminal Cl-.
Topics: Animals; Anion Transport Proteins; Antiporters; Bicarbonates; Body Fluids; Capsaicin; Chlorine; Cystic Fibrosis Transmembrane Conductance Regulator; Duodenum; Ethanol; Gastric Acid; Hexamethonium; Hydrochloric Acid; Intestinal Mucosa; Male; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sulfate Transporters | 2014 |
Effects of esophageal capsaicin instillation on acid induced excitation of secondary peristalsis in humans.
Topics: Adult; Air; Capsaicin; Esophagus; Female; Gastroesophageal Reflux; Heartburn; Humans; Hydrochloric Acid; Instillation, Drug; Male; Mechanoreceptors; Peristalsis; Young Adult | 2016 |
Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1.
Topics: Calcium; Capsaicin; Electrophysiological Phenomena; HEK293 Cells; Hot Temperature; Humans; Hydrochloric Acid; Polymorphism, Single Nucleotide; TRPV Cation Channels | 2016 |
Transient Receptor Potential Vanilloid-1 Channels Contribute to the Regulation of Acid- and Base-Induced Vasomotor Responses.
Topics: Acid-Base Equilibrium; Animals; Capsaicin; Carotid Arteries; Dose-Response Relationship, Drug; Female; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mice, Inbred C57BL; Mice, Knockout; Rats, Wistar; Skin; Sodium Hydroxide; Tail; TRPV Cation Channels; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vasomotor System | 2016 |
QX-314 inhibits acid-induced activation of esophageal nociceptive C fiber neurons.
Topics: Acrylamides; Action Potentials; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Esophagus; Guinea Pigs; Hydrochloric Acid; Lidocaine; Nerve Fibers, Unmyelinated; Nociception; Patch-Clamp Techniques; TRPV Cation Channels | 2019 |
Rapid molecular evolution of pain insensitivity in multiple African rodents.
Topics: Animals; Binding Sites; Capsaicin; Evolution, Molecular; Hydrochloric Acid; Insect Bites and Stings; Isothiocyanates; Mole Rats; NAV1.7 Voltage-Gated Sodium Channel; Nociceptive Pain; Nociceptors; Pain Threshold; Protein Conformation; Sequence Analysis, RNA; Species Specificity; TRPA1 Cation Channel | 2019 |