capsaicin and histamine

capsaicin has been researched along with histamine in 276 studies

Research

Studies (276)

TimeframeStudies, this research(%)All Research%
pre-199036 (13.04)18.7374
1990's101 (36.59)18.2507
2000's69 (25.00)29.6817
2010's57 (20.65)24.3611
2020's13 (4.71)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Arvier, PT; Chahl, LA; Ladd, RJ1
Coleridge, HM; Coleridge, JC1
Asakura, K; Kataura, A; Kojima, T; Narita, S; Shirasaki, H1
Imamura, T; Kambara, T1
Ellis, JL; Undem, BJ1
Ballati, L; Evangelista, S; Manzini, S1
Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M1
Cappugi, P; Lotti, T; Tsampau, D1
Go, K; Namimatsu, A; Okuda, M; Tanimoto, H1
Hirose, T; Nishima, S; Umeno, E1
Imamura, T; Ishikawa, T; Kambara, T; Kokumai, S; Masuyama, K1
Fujii, T; Maeda, Y; Morimoto, H; Murai, M1
Griesbacher, T; Legat, FJ; Lembeck, F1
Desmazes, N; Dusser, DJ; Lacroix, H; Lockhart, A1
Matsumoto, J; Ohuchi, T; Okabe, S; Takeuchi, K; Ueshima, K1
Hameister, WM; Yeates, DB1
Erjefält, J; Forsberg, K; Karlsson, JA; Zackrisson, C1
Bian, RL; Wei, EQ1
Crimi, N; Maccarrone, C; Mistretta, A; Palermo, B; Palermo, F; Polosa, R1
Evangelista, S; Intorre, L; Mengozzi, G; Pacini, F; Soldani, G1
Hameister, WM; Wong, LB; Yeates, DB1
Leung, FW1
Fuller, RW; Studham, J1
Fazekas, A; Györfi, A; Irmes, F; Pósch, E; Rosivall, L1
Andrews, PV; Boyd, RL; Eglezos, A; Helme, RD1
Biggs, DF; Ladenius, RC1
Brokaw, JJ; Hillenbrand, CM; McDonald, DM; White, GW1
Ingenito, EP; Ingram, RH; Martins, MA; Pliss, LB1
Fujii, T; Kiyotoh, S; Morimoto, H; Murai, M; Nishikawa, M1
Alving, K; Hökfelt, T; Lundberg, JM; Matran, R; Panula, P; Sundström, C1
Franco-Cereceda, A; Karlsson, JA; Lou, YP; Lundberg, JM1
Brodda-Jansen, G; Hedqvist, P; Lundeberg, T; Raud, J; Theodorsson, E1
Izumi, H; Karita, K2
Bascom, R; Kagey-Sobotka, A; Proud, D1
Brain, SD; Hughes, SR1
Coyle, AJ; Manzini, S; McKenniff, MG; Page, CP; Perretti, F; Seeds, EA; Spina, D; Tramontana, M1
Ando, M; Araki, S; Honda, I; Kawano, O; Kohrogi, H; Yamaguchi, T1
Drazen, JM; Martins, MA; Shore, SA; Yager, D1
Daffonchio, L; Hernandez, A; Omini, C1
Daffonchio, L; Gallico, L; Hernandez, A; Omini, C1
Esplugues, J; Esplugues, JV; Gil, L; Ramos, EG1
Alving, K; Lacroix, JS; Lundberg, JM; Matran, R1
Arendt-Nielsen, L; Bjerring, P1
Bauer, V; Matusák, O1
Aronin, N; Clements, RS; Leeman, SE1
Inoki, R; Shibutani, T; Yonehara, N1
Kizawa, Y; Takayanagi, I1
Gamse, R; Lundberg, JM; Martling, CR; Saria, A; Theodorsson-Norheim, E; Yan, Z1
Astolfi, GM; Baldi, E; Fusco, B; Geppetti, P; Giuliani, S; Maggi, CA; Parlani, M; Patacchini, R; Santicioli, P; Theodorsson, E1
Drazen, JM; Shore, SA1
Andrews, PV; Helme, RD; Khalil, Z; Thomas, KL1
Fujii, T; Morimoto, H; Senoh, H1
Raybould, HE; Taché, Y1
Bortolami, R; Carobi, C; Draicchio, F; Grassi, S; Lucchi, ML; Manni, E; Pettorossi, VE1
Choudry, NB; Fuller, RW; Pride, NB1
Khalil, Z; Livett, BG; Marley, PD1
Barnes, PJ; Cuss, FM; Dixon, CM; Fuller, RW1
Antal, A; Barthó, L; Holzer, P; Pethö, G; Szolcsányi, J1
Alföldi, P; Hideg, J; Obál, F; Tóth, E1
Bognár, A; Husz, S; Jancsó, G; Obál, F; Tóth-Kása, I1
Leyden, JJ; Soschin, D1
Hua, X; Lundberg, JM; Saria, A; Skofitsch, G1
Fennessy, MR; Stewart, AG; Thompson, DC1
Foster, A; Schellenberg, RR1
Bernstein, JE; Lorincz, AL; Soltani, K; Swift, RM1
Gamse, R; Lembeck, F1
Kongsamut, S; Monsereenusorn, Y; Pezalla, PD1
Foreman, JC; Jordan, CC; Oehme, P; Renner, H1
Lundberg, JM; Martling, CR; Saria, A1
Lembeck, F; Lundberg, JM; Saria, A; Skofitsch, G1
Blum, DJ; McCaffrey, TV1
Benedek, G; Obál, F; Szikszay, M1
Andersson, P; Lundberg, JM; Martling, CR; Saria, A1
Holzer, P; Lembeck, F; Saria, A; Skofitsch, G1
Abelli, L; Evangelista, S; Manzini, S; Page, CP; Perretti, F; Seeds, EA1
Lundblad, L; Rinder, J; Stjärne, P1
Brain, SD; Newbold, P1
Hayashi, K; Kuraishi, Y; Nagasawa, T; Satoh, M1
Drazen, JM; Haley, KJ; Hall, AE; Kobzik, L; Lilly, CM; Rodger, IW1
Inoue, H; Koshihara, Y; Nagata, N1
Amann, R; Donnerer, J; Lanz, I; Schuligoi, R1
Folkerts, G; Ladenius, AR; Nijkamp, FP; van der Linde, HJ1
Andersson, M; Greiff, L; Persson, CG; Svensson, C1
Fujii, T; Hagiwara, D; Maeda, Y; Matsuo, M; Miyake, H; Murai, M; Yamaoka, M1
Bertrand, C; Geppetti, P; Graf, PD; Nadel, JA1
Manzini, S; Perretti, F1
Davison, JS; Mathison, R1
Philip, G; Togias, AG1
Aizawa, H; Hara, N; Inoue, H; Koto, H; Takata, S1
Asakura, K; Kataura, A; Kojima, T; Narita, S; Saito, H1
Boyer, V; D'Ortho, MP; Harf, A; Jarreau, PH; Macquin-Mavier, I1
Anand, A; Paintal, AS; Whitteridge, D1
Baraniuk, JN; Gawin, AZ; Igarashi, Y; Kaliner, MA1
Bertrand, C; Foresi, A; Geppetti, P; Graf, PD; Nadel, JA1
Adcock, JJ; Higenbottam, TW; Mohammed, SP1
Matsumoto, J; Ohuchi, T; Okabe, S; Takeuchi, K1
Lee, LY; Morton, RF1
Lou, YP; Lundberg, JM; Satoh, H1
Manzini, S; Page, CP; Riccio, MM1
Erjefält, I; Luts, A; Persson, CG1
Ladenius, AR; Nijkamp, FP1
Buckley, TL; Engels, F; Henricks, PA; Muis, T; Nijkamp, FP; van Heuven-Nolsen, D1
Luijendijk, SC; Meessen, NE; van der Grinten, CP1
Folgering, HT; Luijendijk, SC; Meeseen, NE; van der Grinten, CP1
Amann, R; Donnerer, J; Herzeg, G; Schuligoi, R1
Andersson, M; Greiff, L; Persson, C; Svensson, C1
Amemiya, T; Fujimura, M; Matsuda, T; Mizuguchi, M; Nishi, K; Ohka, T1
Arantes, FM; Leme, AS; Maldonado, EA; Martins, MA; Warth, Mdo P1
Dimitriadou, V; Garbarg, M; Luffau, G; Miller, HR; Newlands, GJ; Rouleau, A; Schwartz, JC; Trung Tuong, MD1
Carstens, E1
Arden, WA; Fiscus, RR; Lee, LY; Loeffler, BS1
Abdel Salam, OM; Mózsik, G; Szolcsányi, J1
Bergren, DR5
Ando, M; Fujii, K; Goto, E; Hamamoto, J; Hirata, N; Honda, I; Iwagoe, H; Kohrogi, H; Yamaguchi, T1
Gonda, T; Hattori, K; Kakizoe, E; Kobayashi, Y; Okunishi, H; Shimoura, K1
Averbeck, B; Bickel, A; Luz, O; Schmelz, M1
Adcock, JJ; Douglas, GJ; Matsumoto, T; Page, CP; Riccio, MM; Spina, D1
Andersson, RG; Lindström, EG1
Güner, I; Oruç, T; Sahin, G; Simşek, G1
Alkner, U; Andersson, M; Greiff, L; Halldorsdottir, H; Persson, CG; Svensson, C; Wollmer, P1
Fujiwara, R; Izushi, K; Kamei, C; Ohishi, H; Sugimoto, Y; Takada, M; Yamaji, M1
Berti, F; Bianchi, M; Maggi, R; Panerai, AE; Rossoni, G1
Didier, A; Igarashi, Y; Kaliner, MA; Kowalski, ML; Lundgren, JD1
Forster, C; Handwerker, HO; Heyer, G; Weisshaar, E1
Carstens, E; Handwerker, HO; Kuenzler, N1
Chapman, ID; Chilvers, ER; Handley, DA; Morley, J; Templeton, AG1
D'Agostino, B; Falciani, M; Filippelli, A; Rossi, F1
Hageman, C; Högman, M; Hua, X1
Ebersberger, A; Messlinger, K; Oppmann, M; Pawlak, M; Schepelmann, K1
Beckers, JF; Delaunois, A; Dessy-Doizé, C; Gustin, P; Nemery, B; Nemmar, A; Sulon, J1
Cocks, TM; Moffatt, JD1
Gebhart, GF; Su, X; Wachtel, RE1
Kuraishi, Y; Nagasawa, T; Satoh, M; Yamaguchi, T1
Atanassoff, PG; Brull, SJ; Lamotte, RH; Silverman, DG; Zhang, J1
Antunes, E; Brain, SD; Costa, SK; De Nucci, G1
Bedol, D; Dreshaj, IA; Ferguson, DG; Haxhiu, MA; Yamamoto, B1
Carstens, E; Jinks, SL2
Janni, G; Jasmin, L; Ohara, PT; Rabkin, SD1
Schmelz, M1
Lacroix, JS; Malis, DD1
Cirillo, R; Evangelista, S; Lippi, A; Maggi, CA; Manzini, S; Vieira, C1
Fozard, JR; Hannon, JP; Mazzoni, L; Tigani, B; Williams, I1
Fukui, H; Kashiba, H; Senba, E1
Hsu, TH; Kou, YR1
Gitlin, JM; Mitchell, JA; Stanford, SJ1
Beck-Sickinger, AG; Lacroix, JS; Malis, DD; Morel, DR; Nicoucar, K; Rist, B1
Kashiba, H; Senba, E1
Hayashi, K; Ishii, A; Kaise, T; Karasawa, A; Ohmori, K; Sano, J; Sato, H1
Dussor, GO; Flores, CM; Harding-Rose, C; Hargreaves, KM; Kilo, S; Leong, AS1
Canning, BJ; Mazzone, SB; Reynolds, SM1
Eltorp, CT; Hansen, AJ; Ingvardsen, BK; Jørgensen, TK; Lundbaek, JA; Olsen, UB; Thomsen, C1
Abbate, GF; Advenier, C; D'Agostino, B; de Palma, R; Gallelli, L; Marrocco, G; Rossi, F1
Canning, BJ; Mazzone, SB1
Bevan, S; Nicolson, TA; Richards, CD1
Ashton, D; Fransen, JF; Hens, KA; Heylen, L; Hillen, LC; Janssens, F; Jurzak, MR; Leysen, JE; Mahieu, M; Megens, AA; Vermeire, JC; Vermote, PC1
Falkmer, S; Grønbech, JE; Lyng, O; Rydning, A1
Flecknell, P; Laidlaw, A; Rees, JL1
Handwerker, HO; Hilliges, M; Schmelz, M; Schmidt, R; Torebjork, HE; Weidner, C1
Dunker, N; Gollnick, H; Weisshaar, E1
Dugina, YL; Epstein, OI; Kovaleva, VL; Zak, MS1
Giesler, GJ; Honda, CN; LaMotte, RH; Li, J; Simone, DA; Zhang, JM; Zhang, X1
Canning, BJ; Mazzone, SB; Meeker, SN; Mori, N; Reynolds, SM; Undem, BJ1
Baron, R; Binder, A; Jensen, TS; Schattschneider, J; Schwarz, K; Wasner, G1
Kim, BM; Lee, SH; Oh, U; Shim, WS1
Atweh, SF; Jabbur, SJ; Massaad, CA; Poole, S; Saadé, NE; Safieh-Garabedian, B1
ISSEKUTZ, B; LICHTNECKERT, I; NAGY, H1
ISSEKUTZ, B; LICHTNECKERT, I; WINTER, M1
Brozmanova, M; Kollarik, M; Plevkova, J; Revallo, M; Tatar, M; Varechova, S1
Brzozowski, T; Ceranowicz, P; Dembiński, A; Dembiński, M; Konturek, SJ; Pawlik, WW; Warzecha, Z1
Andersson, M; Coman, WB; Fischer-Colbrie, R; Greiff, L; Korsgren, M; Mackay-Sim, A; Persson, CG; Sundler, F; Wallwork, B1
Brozmanova, M; Pecova, R; Plevkova, J; Tatar, M2
Andersson, M; Coman, WB; Greiff, L; Lindberg, H; Marko-Varga, G; Persson, CG; Wallwork, B1
Compte, L; De Diego, A; Macián, V; Martínez, E; Nieto, L; Perpiñá, M; Senent, L1
Kato, M; Kuramasu, A; Mobarakeh, JI; Orito, T; Sakurada, S; Sakurai, E; Yanai, K; Yoshida, A1
Kollarik, M; MacGlashan, DW; Taylor-Clark, TE; Undem, BJ1
Barroso, VM; Canuto, KM; Costa, MF; Leal, LK; Pitombeira, M; Silveira, ER; Viana, GS1
Berglund, M; Dalence-Guzmán, MF; Jönsson, P; Persson, CG; Skogvall, S; Sterner, O; Svensson, K1
Takahashi, K; Toyohira, Y; Tsutsui, M; Ueno, S; Yanagihara, N1
Chang, LW; Chen, SC; Tsai, MH; Wang, HJ; Yu, HS1
Kim, M; Koo, JY; Lee, CH; Lee, MH; Oh, U; Shim, WS; Tak, MH1
Bíró, T; Dobrosi, N; Géczy, T; Marincsák, R; Paus, R; Tóth, BI1
Hartke, T; Hobelmann, JG; Johanek, LM; LaMotte, RH; Maine, DN; Meyer, RA; Ringkamp, M1
Dux, M; Jancsó, G; Pintér, S; Rosta, J; Sántha, P1
Andoh, T; Kosaka, M; Kuraishi, Y; Lee, JB; Nakano, T; Tayama, M1
Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y1
Nassenstein, C; Taylor-Clark, TE; Undem, BJ1
Kamei, C; Kuyama, S; Ogawa, M; Yokota, E1
Carr, R; Handwerker, HO; Johanek, LM; Namer, B; Ringkamp, M; Schmelz, M1
Borzan, J; Friedman, RM; Greenquist, KW; Hartke, T; Johanek, LM; LaMotte, RH; Meyer, RA; Ringkamp, M; Shim, B1
Engel, S; Lee, BB; McLachlan, E; Wasner, G1
Canning, BJ; Chou, YL; Mori, N; Scarupa, MD1
LaMotte, RH; Shimada, SG1
Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Vale, ML1
Emala, CW; Gallos, G; Gleason, NR; Zhang, Y1
Akiyama, T; Carstens, E; Carstens, MI; Merrill, AW; Zanotto, K1
Imatake, K; Matsui, T; Moriyama, M1
Green, BG; LaMotte, RH; Shimada, SG; Sikand, P2
Akiyama, T; Carstens, E; Carstens, MI4
Anderson, DJ; Chen, ZF; Dong, X; Geng, Y; Guan, Y; Kim, A; Kim, S; Kollarik, M; Liu, Q; Patel, KN; Ru, F; Surdenikova, L; Tang, Z; Undem, BJ; Weng, HJ1
Evers, AW; Kraaimaat, FW; van Laarhoven, AI; Wilder-Smith, OH1
Akiyama, T; Carstens, E; Carstens, IM1
Ji, Q; Ji, W; Liang, J1
Liu, B; Lü, H; Qiu, Z; Xu, S; Yu, L; Zhao, T1
Bautista, DM; Bifolck-Fisher, A; Dong, X; Gerhold, KA; Liu, Q; Patel, KN; Wilson, SR1
de Oliveira, SM; Ferreira, J; Gomez, MV; Hoffmeister, C; Rossato, MF; Trevisan, G1
Ikoma, A; Steinhoff, M1
Borzan, J; Hartke, TV; Johanek, LM; LaMotte, RH; Meyer, RA; Ringkamp, M; Schepers, RJ; Shim, B; Shimada, SG1
Jin, H; Kawasaki, H; Kitamura, Y; Koyama, T; Sun, P; Takatori, S; Tangsucharit, P; Zamami, Y1
Gomes, LO; Hara, DB; Rae, GA1
McCoy, ES; Taylor-Blake, B; Zylka, MJ1
Akiyama, T; Carstens, EE; Carstens, MI; Tominaga, M1
Davidson, S; Giesler, GJ; Honda, CN; Khasabov, SG; Moser, HR; Simone, DA; Zhang, X1
Cui, Y; Dong, X; Guan, Y; Han, L; He, S; Kim, Y; Lamotte, RH; Li, Z; Liu, Q; Ma, C; McNeil, B; Nie, H; Patel, KN; Qu, L; Tang, Z; Weng, HJ; Xiao, B1
McCoy, ES; Pribisko, AL; Street, SE; Taylor-Blake, B; Zheng, J; Zylka, MJ1
Brenner, DS; Gereau, RW; Gutmann, DH; O'Brien, DE1
Lü, H; Qiu, Z; Wang, L; Xu, X; Yang, Z; Yu, L1
Almeida, FR; Amaral, MP; Chaves, MH; Costa, DA; Figueiredo, KA; Júnior, FB; Oliveira, FA; Oliveira, IS; Oliveira, RC; Silva, FV1
Akiyama, T; Carstens, E; Carstens, MI; Nagamine, M1
Forster, C; Handwerker, HO; Hartmann, EM1
Borzan, J; Dong, X; Hartke, TV; Klein, AH; Meyer, RA; Ringkamp, M; Turnquist, B; Weng, HJ; Wooten, M1
Copits, BA; Davidson, S; Gereau, RW; Ghetti, A; Page, G; Zhang, J1
Fernando, D; Gibson, RA; McCallum, S; Mistry, H; Robertson, J; Wyres, M; Yosipovitch, G1
Akiyama, T; Carstens, E; Carstens, MI; Takamori, K; Tominaga, M1
Chung, SJ; Jang, YH; Lee, CJ; Lee, H; Lee, SJ; Lim, H; Min, H1
Giesler, GJ; Jansen, NA1
Dörfler, A; Forster, C; Handwerker, HO; Vierow, V; Vogelgsang, R1
Cheng, X; Gao, Y; Li, S; Liu, W; Ni, J; Qi, S; Wang, C; Wang, G; Wang, J; Wang, Y; Wang, Z; Zheng, T1
Davidson, S; Gereau, RW; Leitges, M; Valtcheva, MV; Zhao, C1
Fedin, AN; Kirilina, VM; Kiver, EN; Krivchenko, AI; Smirnova, LE1
Keir, SD; Page, CP; Spina, D1
Akiyama, T; Carstens, E; Carstens, MI; Curtis, E; Nguyen, T1
Huang, Y; Li, J; Ma, C; Shen, L; Wang, T; Xu, Y; Yuan, T; Zhang, W; Zhu, J1
Gegen, T; He, Q; Lan, L; Shi, H; Tang, K; Tang, M; Tang, ZX; Wang, CM; Wang, ZL; Wu, GY; Yang, NN; Yang, Y; Yu, G; Yuan, XL; Zhu, C1
Coutinho, HD; de Albuquerque, TR; de Lacerda Neto, LJ; de Menezes, IR; de Oliveira, LR; de Souza, SD; Dos Santos, AT; Kerntopf, MR; Quintans-Júnior, LJ; Ramos, AG; Santos Sales, V; Wanderley, AG1
Andersen, HH; Arendt-Nielsen, L; Elberling, J; Hoeck, EA; Marker, JB1
Andersen, HH; Arendt-Nielsen, L; Elberling, J; Gazerani, P; Hauberg, LE; Sharma, N1
Able, J; Altmann, S; Berry, LM; Boezio, AA; Boezio, C; Butler, JR; Chu-Moyer, M; Cooke, M; DiMauro, EF; Dineen, TA; Feric Bojic, E; Foti, RS; Fremeau, RT; Gao, H; Graceffa, RF; Gunaydin, H; Guzman-Perez, A; Huang, H; Huang, L; Ilch, C; Jarosh, M; Kornecook, T; Kreiman, CR; La, DS; Ligutti, J; Lin, MJ; Marx, IE; Milgram, BC; Moyer, BD; Nguyen, HN; Peterson, EA; Rescourio, G; Roberts, J; Schenkel, L; Shimanovich, R; Sparling, BA; Stellwagen, J; Taborn, K; Vaida, KR; Wang, J; Weiss, MM; Yeoman, J; Yu, V; Zhu, D1
He, Z; Kamal, GM; Li, Z; Liu, H; Liu, T; Liu, Z; Tian, X; Wang, J; Xiang, H; Xu, F1
Bardoni, R; Barry, DM; Chen, ZF; Jeffry, J; Jin, H; Jin, JH; Kim, R; Liu, XT; Liu, XY; Meng, QT; Mo, P; Peng, JH; Shen, KF; Sun, Y; Tao, A; Wan, L; Yin, J1
Borad, N; Catich, E; Li, N; McKemy, DD; Ongun, S; Palkar, R; Sarkisian, A1
Andersen, HH; Arendt-Nielsen, L; Jensen, LP; Justesen, FD; Pedersen, JB; Sørensen, LL; van Laarhoven, AIM1
Coutinho, HDM; da Costa, RHS; da Silva, BAF; de Menezes, IRA; Fernandes, CN; Garcia, TR; Leite, LHI; Ribeiro-Filho, J; Wanderley, AG1
Shirasaki, T; Soeda, F; Takahama, K; Yokomizo, K; Zhou, JR1
Andersen, HH; Arendt-Nielsen, L; Lo Vecchio, S1
Giesler, GJ; Khasabov, SG; Lipshetz, B; Netoff, TI; Simone, DA; Truong, H1
Cao, T; Tey, HL; Yosipovitch, G1
Akiyama, T; Carstens, E; Davoodi, A; Follansbee, T; Fujii, M; Iodi Carstens, M; Nagamine, M1
Bae, S; Jeong, H; Oh, T; Yu, J1
Agelopoulos, K; Conrad, H; Hatt, H; Hidding, J; Lotts, T; Osada, N; Pereira, MP; Pogatzki-Zahn, E; Schmelz, M; Ständer, S1
Altrichter, S; Church, MK; Deuring, E; Hawro, T; Lehmann, S; Maurer, M; Metz, M; Weller, K1
Bäumer, W; Fukuyama, T; Ganchingco, JRC; Yoder, JA1
Kocan, I; Pecova, R; Pecova, T; Vysehradsky, R1
Aguilera-Lizarraga, J; Alpizar, YA; Berg, M; Boeckxstaens, G; De Man, JG; De Winter, B; Florens, MV; Hanning, N; Jain, P; Perna, E; Talavera, K; Theofanous, SA; Vanden Berghe, P; Wouters, M1
Deuring, E; Hawro, T; Lehmann, S; Maurer, M; Metz, M; Scheffel, J; Weller, K1
Bíró, T; Hanyicska, M; Kelemen, B; Kim, N; Lisztes, E; Oláh, A; Pénzes, Z; Pinto, S; Rohács, T; Shu, B; Tóth, BI; Vladár, A; Voets, T; Vriens, J1
Elberling, J; Hoffmann, S1
Lai, YE; Lascelles, BDX; Marcus, KL; Nolan, MW; Price, ML; Robertson, JB1
Ballester, GF; Butron, L; Devesa, I; Fernández-Carvajal, A; Ferrer-Montiel, A; Genazzani, AA; González-Rodríguez, S; Nikolaeva-Koleva, M; Pirali, T; Serafini, M; Valente, P1
Fang, Y; Ma, C; Tao, J; Wang, T1
Belboukhari, N; Cheriti, A; Ould El Hadj-Khelil, A; Seddiki, LS; Sekkoum, K; Sulaiman, MR1
Bäumer, W; Kietzmann, M; Mishra, SK; Rossbach, K; Stark, H; Wilzopolski, J1
De Luca, R; Haas, HL; Kernder, A; Mazur, K; Sergeeva, OA1
Chen, Z; Escamilla-Rivera, V; Jung, S; LaMotte, RH; Malewicz, NM; Oeck, S; Rattray, Z; Tang, X; Zhou, J1
Akiyama, T; Bystrom, L; Ishida, H; Markan, A; Pavlenko, D; Todurga Seven, Z; Verpile, R1

Reviews

10 review(s) available for capsaicin and histamine

ArticleYear
Substance P in peripheral sensory processes.
    Ciba Foundation symposium, 1982, Issue:91

    Topics: Animals; Axonal Transport; Axons; Capsaicin; Evoked Potentials; Femoral Nerve; Histamine; Ligation; Nerve Endings; Neurons, Afferent; Peripheral Nerves; Sciatic Nerve; Somatostatin; Substance P; Vasodilation

1982
Capsaicin--a literature survey.
    Critical reviews in toxicology, 1982, Volume: 10, Issue:4

    Topics: Analgesia; Animals; Blood Pressure; Body Temperature Regulation; Capsaicin; Cardiovascular System; Chemical Phenomena; Chemistry; Colon; Dose-Response Relationship, Drug; Drug Tolerance; Fatty Acids, Unsaturated; Heart Rate; Histamine; Intestine, Small; Liver; Muscle, Smooth, Vascular; Myocardial Contraction; Pain; Phagocytosis; Respiratory System; Stomach Ulcer; Substance P; Vagus Nerve

1982
Nonallergic rhinitis. Pathophysiology and models for study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1995, Volume: 252 Suppl 1

    Topics: Capsaicin; Cold Temperature; Histamine; Humans; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Rhinitis

1995
Various methods for testing nasal responses in vivo: a critical review.
    Acta oto-laryngologica, 1995, Volume: 115, Issue:6

    Topics: Alkaloids; Allergens; Aspirin; Bronchoconstrictor Agents; Capsaicin; Histamine; Humans; Methacholine Chloride; Nasal Lavage Fluid; Nasal Provocation Tests; Rhinitis, Allergic, Perennial

1995
[Evaluation of various antagonists of CGRP, a neuromediator implicated in the inflammatory mechanisms of nasal mucosa].
    Schweizerische medizinische Wochenschrift, 2000, Volume: Suppl 125

    Topics: Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Humans; Inflammation; Nasal Mucosa

2000
[Primary sensory neurons expressing histamine H1-receptor mRNA].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:1

    Topics: Animals; Capsaicin; Gene Expression; Histamine; Humans; Neuralgia; Neurons, Afferent; Neuropeptides; Receptors, Histamine H1; RNA, Messenger; Up-Regulation

2001
TRP channels as novel players in the pathogenesis and therapy of itch.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:8

    Topics: Animals; Cannabinoids; Capsaicin; Central Nervous System; Histamine; Humans; Inflammation Mediators; Nerve Growth Factors; Neurons; Neurons, Afferent; Neuropeptides; Pain; Pruritus; Spinal Cord; Substance P; Temperature; Transient Receptor Potential Channels; TRPV Cation Channels

2007
Assessment of Itch and Pain in Animal Models and Human Subjects.
    Advances in experimental medicine and biology, 2016, Volume: 904

    Topics: Analgesics; Animals; Antipruritics; Avoidance Learning; Capsaicin; Conditioning, Classical; Emotions; Histamine; Histamine Antagonists; Humans; Mice; Models, Animal; Nociception; Nontherapeutic Human Experimentation; Organ Specificity; Pain; Pain Measurement; Physical Stimulation; Pruritus; Rats; Species Specificity

2016
Chronic Pruritus in the Geriatric Population.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Antidepressive Agents; Antipruritics; Calcineurin Inhibitors; Capsaicin; Cholestasis; Chronic Disease; Emollients; Histamine; Histamine Antagonists; Humans; Kidney Failure, Chronic; Liver Diseases; Menthol; Nervous System Diseases; Palliative Care; Paraneoplastic Syndromes; Pruritus; Skin Aging; Skin Diseases; Urticaria

2018
Itch and Cough - Similar Role of Sensory Nerves in Their Pathogenesis.
    Physiological research, 2020, 03-27, Volume: 69, Issue:Suppl 1

    Topics: Animals; Capsaicin; Cough; Histamine; Histamine Agonists; Humans; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons, Afferent; Peripheral Nerves; Pruritus; Sensory Receptor Cells; Sensory System Agents

2020

Trials

16 trial(s) available for capsaicin and histamine

ArticleYear
Effect of topical application with capsaicin on skin responses to bradykinin and histamine in man.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1992, Volume: 22, Issue:10

    Topics: Administration, Cutaneous; Adolescent; Adult; Bradykinin; Capsaicin; Double-Blind Method; Female; Histamine; Histamine Antagonists; Humans; Injections, Intradermal; Male; Middle Aged; Nerve Endings; Skin

1992
The effect of oral terfenadine on the sensitivity of the cough reflex in normal volunteers.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:1

    Topics: Administration, Oral; Adult; Capsaicin; Cough; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Humans; Random Allocation; Reflex; Terfenadine

1992
Effect of topical capsaicin on the cutaneous reactions and itching to histamine in atopic eczema compared to healthy skin.
    Archives of dermatological research, 1998, Volume: 290, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Capsaicin; Dermatitis, Allergic Contact; Dermatitis, Atopic; Erythema; Female; Histamine; Humans; Male; Middle Aged; Paresthesia; Pruritus; Severity of Illness Index; Skin; Skin Tests

1998
Attenuation of experimental pruritus and mechanically evoked dysesthesiae in an area of cutaneous allodynia.
    Somatosensory & motor research, 1999, Volume: 16, Issue:4

    Topics: Adult; Capsaicin; Forearm; Histamine; Humans; Hyperalgesia; Injections, Intradermal; Male; Middle Aged; Pain; Paresthesia; Physical Stimulation; Pruritus; Skin; Skin Physiological Phenomena; Skin Tests; Time Factors

1999
Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens.
    Journal of neurophysiology, 2003, Volume: 89, Issue:5

    Topics: Acetylcholine; Adult; Bradykinin; Capsaicin; Dinoprostone; Electric Stimulation; Female; Histamine; Humans; Inflammation Mediators; Male; Microdialysis; Nerve Fibers, Unmyelinated; Nociceptors; Pain; Pain Measurement; Peroneal Nerve; Pruritus; Psychophysics; Reflex; Sensory Thresholds; Serotonin; Skin; Sympathetic Nervous System

2003
Topical capsaicin therapy in humans with hemodialysis-related pruritus.
    Neuroscience letters, 2003, Jul-24, Volume: 345, Issue:3

    Topics: Administration, Topical; Adult; Capsaicin; Case-Control Studies; Drug Administration Schedule; Female; Free Radical Scavengers; Histamine; Humans; Iontophoresis; Male; Middle Aged; Pruritus; Renal Dialysis; Serotonin; Time Factors

2003
Interaction between histamine-induced itch and experimental muscle pain.
    European journal of pain (London, England), 2004, Volume: 8, Issue:3

    Topics: Adult; Afferent Pathways; Capsaicin; Central Nervous System; Female; Histamine; Humans; Male; Models, Neurological; Muscle, Skeletal; Neural Inhibition; Nociceptors; Pain; Pruritus; Sensory Receptor Cells; Skin

2004
The effects of nasal histamine challenge on cough reflex in healthy volunteers.
    Pulmonary pharmacology & therapeutics, 2006, Volume: 19, Issue:2

    Topics: Administration, Intranasal; Adult; Afferent Pathways; Airway Obstruction; Capsaicin; Cough; Double-Blind Method; Female; Histamine; Humans; Male; Nasal Cavity; Nasal Mucosa; Reflex; Respiration

2006
Challenge-induced plasma exudation and mucinous secretion in human airways.
    Clinical physiology and functional imaging, 2005, Volume: 25, Issue:4

    Topics: Adult; alpha-Macroglobulins; Capsaicin; Dose-Response Relationship, Drug; Exudates and Transudates; Female; Fucose; Histamine; Humans; Lung; Male; Methacholine Chloride; Mucins; Nasal Mucosa; Plasma; Respiratory Mucosa

2005
Effects of intranasal histamine on the cough reflex in subjects with allergic rhinitis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56 Suppl 4

    Topics: Administration, Inhalation; Administration, Intranasal; Adult; Aerosols; Capsaicin; Cough; Dose-Response Relationship, Drug; Female; Histamine; Humans; Male; Nasal Mucosa; Nasal Provocation Tests; Nebulizers and Vaporizers; Neurons, Afferent; Reflex; Respiration; Rhinitis, Allergic, Seasonal; Seasons

2005
Similar itch and nociceptive sensations evoked by punctate cutaneous application of capsaicin, histamine and cowhage.
    Pain, 2009, Volume: 144, Issue:1-2

    Topics: Area Under Curve; Capsaicin; Dose-Response Relationship, Drug; Female; Histamine; Humans; Incidence; Injections, Intradermal; Linear Models; Male; Mucuna; Pain; Pain Measurement; Pain Threshold; Paresthesia; Plant Structures; Pruritus; Sensation; Skin Physiological Phenomena; Time Factors

2009
Sensory responses to injection and punctate application of capsaicin and histamine to the skin.
    Pain, 2011, Volume: 152, Issue:11

    Topics: Acute Pain; Capsaicin; Female; Histamine; Histamine Agonists; Humans; Hyperalgesia; Injections, Intradermal; Male; Nociceptors; Sensory System Agents; Skin

2011
Gender differences in itch and pain-related sensations provoked by histamine, cowhage and capsaicin.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:1

    Topics: Adult; Capsaicin; Female; Germany; Histamine; Humans; Laser-Doppler Flowmetry; Male; Mucuna; Pain; Pain Measurement; Pain Threshold; Plant Extracts; Pruritus; Regional Blood Flow; Sex Factors; Skin; Surveys and Questionnaires; Time Factors; Young Adult

2015
A randomised trial evaluating the effects of the TRPV1 antagonist SB705498 on pruritus induced by histamine, and cowhage challenge in healthy volunteers.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Administration, Topical; Adult; Capsaicin; Healthy Volunteers; Histamine; Humans; Male; Middle Aged; Pruritus; Pyrrolidines; Skin; TRPV Cation Channels; Urea

2014
Antipruritic effect of pretreatment with topical capsaicin 8% on histamine- and cowhage-evoked itch in healthy volunteers: a randomized, vehicle-controlled, proof-of-concept trial.
    The British journal of dermatology, 2017, Volume: 177, Issue:1

    Topics: Administration, Cutaneous; Antipruritics; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; Forearm; Healthy Volunteers; Histamine; Humans; Male; Mucuna; Pruritus; Transdermal Patch; Young Adult

2017
Anti-pruritic effect of topical capsaicin against histamine-induced pruritus on canine skin.
    Polish journal of veterinary sciences, 2018, Volume: 21, Issue:4

    Topics: Administration, Topical; Animals; Capsaicin; Dog Diseases; Dogs; Female; Histamine; Injections, Intradermal; Male; Pruritus; Skin

2018

Other Studies

250 other study(ies) available for capsaicin and histamine

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Modification by capsaicin and compound 48/80 of dye leakage induced by irritants in the rat.
    British journal of pharmacology, 1977, Volume: 59, Issue:1

    Topics: Adenosine Triphosphate; Animals; Azo Compounds; Bradykinin; Capsaicin; Edema; Evans Blue; Fatty Acids, Unsaturated; Formaldehyde; Histamine; Hydrochloric Acid; Male; Models, Biological; p-Methoxy-N-methylphenethylamine; Potassium Chloride; Prostaglandins E; Rats; Serotonin; Skin

1977
Impulse activity in afferent vagal C-fibres with endings in the intrapulmonary airways of dogs.
    Respiration physiology, 1977, Volume: 29, Issue:2

    Topics: Action Potentials; Animals; Bronchi; Capsaicin; Dogs; Evoked Potentials; Hemodynamics; Histamine; Lung; Nerve Fibers; Neural Conduction; Pulmonary Stretch Receptors; Pulmonary Ventilation; Refractory Period, Electrophysiological; Vagus Nerve

1977
Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs.
    Acta oto-laryngologica, 1992, Volume: 112, Issue:3

    Topics: Administration, Intranasal; Administration, Topical; Animals; Atropine; Benzenesulfonates; Capsaicin; Chromones; Coloring Agents; Diphenhydramine; Exudates and Transudates; Guinea Pigs; Histamine; Histamine Release; Injections, Subcutaneous; Lidocaine; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Substance P

1992
Substance P as a potent stimulator of sneeze responses in experimental allergic rhinitis of guinea pigs.
    Agents and actions, 1992, Volume: 37, Issue:3-4

    Topics: Animals; Ascaris; Capsaicin; Guinea Pigs; Histamine; Nasal Mucosa; Rhinitis, Allergic, Seasonal; Sneezing; Substance P

1992
Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2

    Topics: Animals; Antigens; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Nerve Fibers; Neurokinin A; Peptide Fragments; Prostaglandin D2; Pyrilamine; Serotonin; Tetrodotoxin; Trachea; Vagus Nerve

1992
Repeated antigen challenge induced airway hyperresponsiveness to neurokinin A and vagal non-adrenergic, non-cholinergic (NANC) stimulation in guinea pigs.
    Life sciences, 1992, Volume: 51, Issue:11

    Topics: Acetylcholine; Aerosols; Animals; Antigens; Bronchial Hyperreactivity; Capsaicin; Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Guinea Pigs; Histamine; Male; Neurokinin A; Neurons, Afferent; Receptors, Neurotransmitter; Receptors, Tachykinin; Sensitivity and Specificity; Vagus Nerve

1992
Antiinflammatory and analgesic activity of a non-peptide substance P receptor antagonist.
    European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Male; Mice; Muscle Contraction; Platelet Activating Factor; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Skin; SRS-A; Tachykinins; Ureter

1992
Substance P provokes cutaneous erythema and edema through a histamine-independent pathway.
    International journal of dermatology, 1992, Volume: 31, Issue:3

    Topics: Adult; Capsaicin; Edema; Erythema; Female; Histamine; Humans; Hydroxyzine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Substance P

1992
Mechanism of nasal secretion mediated via nerve reflex in guinea pigs and evaluation of antiallergic drugs.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:2

    Topics: Allergens; Aminopyridines; Animals; Atropine Derivatives; Bronchodilator Agents; Capsaicin; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Hypersensitivity; Lidocaine; Methacholine Chloride; Nasal Mucosa; ortho-Aminobenzoates; Parasympatholytics; Phthalazines; Pyrilamine; Reflex

1992
Pretreatment with aerosolized capsaicin potentiates histamine-induced bronchoconstriction in guinea pigs.
    The American review of respiratory disease, 1992, Volume: 146, Issue:1

    Topics: Aerosols; Animals; Bronchoconstriction; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; Male; Substance P; Trachea

1992
Effect of capsaicin as a neuropeptide-releasing substance on sneezing reflex in a type I allergic animal model.
    International archives of allergy and immunology, 1992, Volume: 98, Issue:3

    Topics: Animals; Capsaicin; Guinea Pigs; Histamine; Hypersensitivity; Male; Nasal Mucosa; Neuropeptides; Reflex; Sneezing; Substance P

1992
Effects of the tripeptide substance P antagonist, FR113680, on airway constriction and airway edema induced by neurokinins in guinea-pigs.
    European journal of pharmacology, 1992, Jun-24, Volume: 217, Issue:1

    Topics: Amino Acid Sequence; Animals; Bronchi; Bronchoconstriction; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; Kinins; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Oligopeptides; Pulmonary Edema; Substance P; Trachea

1992
CP-96,345, a non-peptide antagonist of substance P: I. Effects on the actions mediated by substance P and related tachykinins on the guinea-pig ileum and rabbit jejunum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:3

    Topics: Animals; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Peristalsis; Rabbits; Stereoisomerism; Substance P; Tachykinins

1992
Carboxypeptidase M-like enzyme modulates the noncholinergic bronchoconstrictor response in guinea pig.
    American journal of respiratory cell and molecular biology, 1992, Volume: 7, Issue:5

    Topics: 3-Mercaptopropionic Acid; Animals; Bradykinin; Bronchoconstriction; Capsaicin; Electric Stimulation; GPI-Linked Proteins; Guinea Pigs; Histamine; Male; Metalloendopeptidases; Neurokinin A; Receptors, Cholinergic; Substance P; Vagus Nerve

1992
Induction of duodenal ulcers in sensory deafferented rats following histamine infusion.
    Digestion, 1992, Volume: 51, Issue:4

    Topics: Animals; Bicarbonates; Capsaicin; Duodenal Ulcer; Duodenum; Gastric Acid; Histamine; Intestinal Mucosa; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Time Factors

1992
Alveolar epithelial permeability in baboons: histamine and capsaicin.
    The Journal of physiology, 1992, Volume: 450

    Topics: Animals; Capsaicin; Epithelium; Female; Histamine; Lung; Male; Neurons, Afferent; Papio; Permeability; Pulmonary Alveoli; Respiration; Technetium Tc 99m Pentetate

1992
Relationship of airway responsiveness to agents causing bronchoconstriction and cough in sensitized guinea-pigs.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:3

    Topics: Administration, Inhalation; Animals; Antigens, Helminth; Ascaris suum; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Capsaicin; Citrates; Citric Acid; Cough; Female; Guinea Pigs; Histamine; Male; Smoke

1992
Vascular permeability increased by histamine aerosol, capsaicin, and electric stimulation of vagus nerves in guinea pigs.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:4

    Topics: Aerosols; Animals; Bronchi; Capillary Permeability; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Heart; Histamine; Male; Trachea; Vagus Nerve

1992
Acute intragastric application of capsaicin inhibits 2-deoxy-D-glucose--but not histamine-induced gastric acid secretion in the dog.
    Neuropeptides, 1992, Volume: 23, Issue:4

    Topics: Animals; Basal Metabolism; Capsaicin; Deoxyglucose; Dogs; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Intubation, Gastrointestinal; Male; Time Factors

1992
Tracheal ciliary beat frequency in baboons: effects of peripheral histamine and capsaicin.
    Agents and actions, 1992, Volume: 35, Issue:3-4

    Topics: Animals; Capsaicin; Cilia; Female; Histamine; Male; Papio; Trachea

1992
Modulation of autoregulatory escape by capsaicin-sensitive afferent nerves in rat stomach.
    The American journal of physiology, 1992, Volume: 262, Issue:2 Pt 2

    Topics: Afferent Pathways; Animals; Blood Vessels; Capsaicin; Epinephrine; Histamine; Homeostasis; Male; Nervous System; Rats; Regional Blood Flow; Stomach; Vasoconstriction

1992
Role of histamine in the development of neurogenic inflammation of rat oral mucosa.
    Agents and actions, 1991, Volume: 32, Issue:3-4

    Topics: Animals; Atropine; Capillary Permeability; Capsaicin; Cimetidine; Ethylenediamines; Evans Blue; Histamine; Histamine H1 Antagonists; Male; Mouth Mucosa; Muscarinic Antagonists; Neuritis; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Muscarinic; Vasodilation

1991
Effects of capsaicin treatment on immunoglobulin secretion in the rat: further evidence for involvement of tachykinin-containing afferent nerves.
    Journal of neuroimmunology, 1990, Volume: 26, Issue:2

    Topics: Animals; Antigen-Presenting Cells; Capsaicin; Cell Count; Female; Histamine; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Kinetics; Neurons, Afferent; Pyrilamine; Rats; Rats, Inbred Strains; Substance P; Tachykinins

1990
Capsaicin selectively reduces airway responses to histamine, substance P and vagal stimulation.
    European journal of pharmacology, 1990, Jan-03, Volume: 175, Issue:1

    Topics: Animals; Capsaicin; Electric Stimulation; Female; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Methacholine Compounds; Respiratory System; Substance P; Vagus Nerve

1990
Mechanism of tachyphylaxis associated with neurogenic plasma extravasation in the rat trachea.
    The American review of respiratory disease, 1990, Volume: 141, Issue:6

    Topics: Animals; Capillary Permeability; Capsaicin; Electric Stimulation; Female; Histamine; Rats; Stimulation, Chemical; Substance P; Tachykinins; Tachyphylaxis; Trachea; Vagus Nerve

1990
Effects of capsaicin on mechanical, cellular, and mediator responses to antigen in sensitized guinea pigs.
    The American review of respiratory disease, 1991, Volume: 143, Issue:3

    Topics: Animals; Antigens; Bronchoalveolar Lavage Fluid; Capsaicin; Guinea Pigs; Histamine; Immunization; Leukotrienes; Lung Compliance; Male; Neurokinin A; Ovalbumin; Prostaglandins; Substance P; Thromboxane B2

1991
Effects of actinomycin D on airway constriction induced by tachykinins and capsaicin in guinea-pigs.
    European journal of pharmacology, 1991, Mar-05, Volume: 194, Issue:2-3

    Topics: Airway Resistance; Animals; Capsaicin; Dactinomycin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Male; Neurokinin A; Substance P; Tachykinins; Trachea

1991
Association between histamine-containing mast cells and sensory nerves in the skin and airways of control and capsaicin-treated pigs.
    Cell and tissue research, 1991, Volume: 264, Issue:3

    Topics: Animals; Antigens, Helminth; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Hypersensitivity; Immunohistochemistry; Leukocytes; Mast Cells; Neurons, Afferent; Respiratory System; Skin; Substance P; Swine

1991
Selectivity of ruthenium red in inhibiting bronchoconstriction and CGRP release induced by afferent C-fibre activation in the guinea-pig lung.
    Acta physiologica Scandinavica, 1991, Volume: 142, Issue:2

    Topics: Animals; Bradykinin; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Citrates; Citric Acid; Cough; Diterpenes; Female; Guinea Pigs; Histamine; Lung; Male; Neurons, Afferent; Nicotine; Ruthenium Red; Smoking; Vagus Nerve

1991
Potent anti-inflammatory action of calcitonin gene-related peptide.
    Biochemical and biophysical research communications, 1991, Nov-14, Volume: 180, Issue:3

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; Cricetinae; Edema; Female; Histamine; Humans; Inflammation; Leukotriene B4; Male; Middle Aged; Mouth Mucosa; Rats; Serotonin; Skin; Skin Physiological Phenomena; Substance P

1991
Axon reflex vasodilatation in human skin measured by a laser Doppler technique.
    The Japanese journal of physiology, 1991, Volume: 41, Issue:5

    Topics: Adult; Axons; Blood Flow Velocity; Capsaicin; Female; Forearm; Histamine; Histamine Antagonists; Humans; Lasers; Male; Middle Aged; Reflex; Skin; Substance P; Vasodilation

1991
Effect of intranasal capsaicin on symptoms and mediator release.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Administration, Intranasal; Adult; Albumins; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Female; Histamine; Humans; Kinins; Male; Mast Cells; Nerve Fibers; Peptide Hydrolases; Rhinitis; Stimulation, Chemical; Tobacco Smoke Pollution

1991
A calcitonin gene-related peptide (CGRP) antagonist (CGRP8-37) inhibits microvascular responses induced by CGRP and capsaicin in skin.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: Alprostadil; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Drug Synergism; Edema; Histamine; Male; Microcirculation; Peptide Fragments; Rabbits; Serum Albumin, Radio-Iodinated; Skin; Vasodilator Agents; Xenon Radioisotopes

1991
Effect of capsaicin on PAF-induced bronchial hyperresponsiveness and pulmonary cell accumulation in the rabbit.
    British journal of pharmacology, 1991, Volume: 103, Issue:1

    Topics: Anesthesia; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Lung; Nerve Fibers; Platelet Activating Factor; Rabbits; Radioimmunoassay; Serum Albumin, Bovine

1991
Inhibition of neutral endopeptidase potentiates bronchial contraction induced by immune response in guinea pigs in vitro.
    The American review of respiratory disease, 1991, Volume: 144, Issue:3 Pt 1

    Topics: Animals; Bronchi; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; In Vitro Techniques; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Serotonin; SRS-A; Thiorphan

1991
Role of capsaicin-sensitive neurons in histamine-induced luminal liquid in small airways.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1991, Volume: 21 Suppl 1

    Topics: Animals; Body Fluids; Capsaicin; Guinea Pigs; Histamine; Lung; Male; Microscopy, Electron, Scanning; Neurons; Tachykinins

1991
Sensory neuropeptides are involved in cigarette smoke induced airway hyperreactivity in guinea-pig.
    Agents and actions. Supplements, 1990, Volume: 31

    Topics: Acetylcholine; Animals; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hydrocortisone; Male; Neuropeptides; Nicotiana; Plants, Toxic; Respiratory Hypersensitivity; Sensation; Smoke; Vagotomy

1990
Airway hyperreactivity induced by active cigarette smoke exposure in guinea-pigs: possible role of sensory neuropeptides.
    Pulmonary pharmacology, 1990, Volume: 3, Issue:3

    Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Guinea Pigs; Histamine; Male; Neuropeptides; Smoking

1990
Influence of capsaicin-sensitive afferent neurones on the acid secretory responses of the rat stomach in vivo.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: Anesthesia; Animals; Blood Glucose; Capsaicin; Carbachol; Female; Ganglia, Sympathetic; Gastric Acid; Gastric Mucosa; Histamine; Insulin; Intubation, Gastrointestinal; Male; Neurons, Afferent; Pentagastrin; Rats; Rats, Inbred Strains; Vagotomy

1990
Capsaicin and histamine antagonist-sensitive mechanisms in the immediate allergic reaction of pig airways.
    Acta physiologica Scandinavica, 1990, Volume: 138, Issue:1

    Topics: Airway Obstruction; Animals; Antigens, Helminth; Ascaris; Bronchi; Capsaicin; Histamine; Larynx; Nose; Swine; Vascular Resistance

1990
Inhibition of histamine skin flare reaction following repeated topical applications of capsaicin.
    Allergy, 1990, Volume: 45, Issue:2

    Topics: Administration, Topical; Adult; Capsaicin; Dose-Response Relationship, Immunologic; Erythema; Histamine; Humans; Middle Aged; Nerve Fibers; Skin

1990
Evidence that sensory neurons participate in the non-cholinergic, non-adrenergic contractile response of the guinea-pig ileum.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:5

    Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Guanethidine; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurons, Afferent; Substance P

1986
Diminished flare response in neuropathic diabetic patients. Comparison of effects of substance P, histamine, and capsaicin.
    Diabetes, 1987, Volume: 36, Issue:10

    Topics: Capsaicin; Diabetic Neuropathies; Female; Histamine; Humans; Male; Middle Aged; Nerve Fibers; Peripheral Nerves; Skin Tests; Substance P

1987
Contribution of substance P to heat-induced edema in rat paw.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Animals; Bradykinin; Capsaicin; Denervation; Edema; Histamine; Hot Temperature; Male; Pyridazines; Rats; Rats, Inbred Strains; Substance P

1987
Substance P-containing nerves mediate nicotine-induced contractions of rabbit bronchial smooth muscle.
    General pharmacology, 1988, Volume: 19, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Bronchi; Capsaicin; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nicotine; Physostigmine; Rabbits; Substance P

1988
Investigation of mechanisms of the flare and wheal reactions in human skin by band method.
    Brain research, 1988, May-24, Volume: 449, Issue:1-2

    Topics: Adult; Axons; Capsaicin; Histamine; Humans; Neurotensin; Nicotine; Skin; Skin Tests; Substance P

1988
Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium, and vagal nerve stimulation.
    The American review of respiratory disease, 1988, Volume: 137, Issue:6

    Topics: Animals; Bradykinin; Capsaicin; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Nervous System; Neurokinin A; Pulmonary Artery; Sensation; Substance P; Tachykinins; Trachea; Vagus Nerve

1988
Regional differences in the motor response to capsaicin in the guinea-pig urinary bladder: relative role of pre- and postjunctional factors related to neuropeptide-containing sensory nerves.
    Neuroscience, 1988, Volume: 27, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclic AMP; Guinea Pigs; Histamine; Immune Sera; In Vitro Techniques; Male; Muscle Contraction; Neurons, Afferent; Neuropeptides; Substance P; Tetrodotoxin; Urinary Bladder

1988
Enhanced airway responses to substance P after repeated challenge in guinea pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:2

    Topics: Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Lung Compliance; Male; Muscle Contraction; Pyrilamine; Respiratory Physiological Phenomena; Respiratory System; Substance P

1989
Substance P induced hydrolysis of inositol phospholipids in rat skin in an in vivo model of inflammation.
    Neuropeptides, 1989, Volume: 13, Issue:3

    Topics: Animals; Blister; Capillary Permeability; Capsaicin; Histamine; Hydrolysis; Inflammation; Phosphatidylinositols; Pyrilamine; Rats; Skin; Substance P

1989
Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:3

    Topics: Animals; Capsaicin; Carbachol; Edema; Histamine; Male; Neurons, Afferent; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Skin Physiological Phenomena; SRS-A; Substance P; Trachea

1989
Capsaicin-sensitive vagal afferent fibers and stimulation of gastric acid secretion in anesthetized rats.
    European journal of pharmacology, 1989, Aug-22, Volume: 167, Issue:2

    Topics: Anesthesia; Animals; Bethanechol Compounds; Capsaicin; Gastric Acid; Histamine; Male; Neurons, Afferent; Pentagastrin; Rats; Rats, Inbred Strains; Stimulation, Chemical; Vagus Nerve

1989
On the nature of the afferent fibers of oculomotor nerve.
    Archives italiennes de biologie, 1989, Volume: 127, Issue:2

    Topics: Animals; Bradykinin; Capsaicin; Histamine; Hot Temperature; Nociceptors; Oculomotor Nerve; Pain; Sheep

1989
Sensitivity of the human cough reflex: effect of inflammatory mediators prostaglandin E2, bradykinin, and histamine.
    The American review of respiratory disease, 1989, Volume: 140, Issue:1

    Topics: Adult; Airway Resistance; Bradykinin; Capsaicin; Citrates; Citric Acid; Cough; Dinoprostone; Female; Histamine; Humans; Male; Reflex; Sensory Receptor Cells

1989
Sensory fibres modulate histamine-induced catecholamine secretion from the rat adrenal medulla and sympathetic nerves.
    The Journal of physiology, 1987, Volume: 391

    Topics: Adrenal Medulla; Adrenalectomy; Animals; Capsaicin; Denervation; Epinephrine; Female; Histamine; Male; Nerve Fibers; Neurons; Neurons, Afferent; Norepinephrine; Rats; Rats, Inbred BUF; Sympathectomy, Chemical; Sympathetic Nervous System

1987
Bradykinin-induced bronchoconstriction in humans. Mode of action.
    The American review of respiratory disease, 1987, Volume: 135, Issue:1

    Topics: Administration, Inhalation; Aged; Asthma; Bradykinin; Bronchi; Bronchial Provocation Tests; Capsaicin; Constriction; Histamine; Humans; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle, Smooth

1987
Two types of relaxation due to capsaicin in the guinea pig isolated ileum.
    Neuroscience letters, 1987, Oct-16, Volume: 81, Issue:1-2

    Topics: Animals; Atropine; Capsaicin; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phentolamine; Propranolol; Tetrodotoxin

1987
Capsaicin pretreatment reduces the gastric acid secretion elicited by histamine but does not affect the responses to carbachol and pentagastrin.
    European journal of pharmacology, 1986, Apr-29, Volume: 123, Issue:3

    Topics: Animals; Capsaicin; Carbachol; Drug Interactions; Gastric Acid; Histamine; Male; Pentagastrin; Rats; Time Factors

1986
Capsaicin prevents histamine-induced itching.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Axons; Capsaicin; Female; Histamine; Humans; Male; Mustard Plant; Neurons, Afferent; Plant Extracts; Plant Oils; Pruritus; Reflex; Time Factors

1986
Sorbic acid-induced erythema and edema.
    Journal of the American Academy of Dermatology, 1986, Volume: 14, Issue:2 Pt 1

    Topics: Administration, Topical; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Capsaicin; Cosmetics; Dermatitis, Atopic; Dose-Response Relationship, Drug; Edema; Erythema; Fatty Acids, Unsaturated; Histamine; Humans; Hydrocortisone; Hydroxyzine; Lidocaine; Mast Cells; Pharmaceutic Aids; Preservatives, Pharmaceutical; Sorbic Acid

1986
Inhibition of compound 48/80--induced vascular protein leakage by pretreatment with capsaicin and a substance P antagonist.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 328, Issue:1

    Topics: Animals; Capillary Permeability; Capsaicin; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Histamine; Muscle Proteins; Muscle, Smooth, Vascular; p-Methoxy-N-methylphenethylamine; Rats; Substance P

1984
Involvement of capsaicin-sensitive afferent neurones in a vagal-dependent interaction between leukotriene D4 and histamine on bronchomotor tone.
    Agents and actions, 1984, Volume: 15, Issue:5-6

    Topics: Airway Resistance; Animals; Bronchi; Capsaicin; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Indomethacin; Male; Nerve Fibers; Neurons, Afferent; SRS-A; Substance P; Vagus Nerve

1984
In vitro responses of human asthmatic airway and pulmonary vascular smooth muscle.
    International archives of allergy and applied immunology, 1984, Volume: 75, Issue:3

    Topics: Allergens; Asthma; Bronchi; Capsaicin; Histamine; Humans; In Vitro Techniques; Leukotriene B4; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Poaceae; Pulmonary Artery; Pulmonary Veins; Serotonin

1984
Inhibition of axon reflex vasodilatation by topically applied capsaicin.
    The Journal of investigative dermatology, 1981, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Axons; Capsaicin; Fatty Acids, Unsaturated; Histamine; Humans; Neural Inhibition; Reflex; Skin; Substance P; Vasodilation

1981
Structure-activity relationships for some substance P-related peptides that cause wheal and flare reactions in human skin.
    The Journal of physiology, 1983, Volume: 335

    Topics: Adenosine Triphosphate; Adult; Autacoids; Capillary Permeability; Capsaicin; Chlorpheniramine; Dose-Response Relationship, Drug; Eledoisin; Histamine; Humans; Intercellular Signaling Peptides and Proteins; Middle Aged; Peptides; Physalaemin; Skin; Structure-Activity Relationship; Substance P; Time Factors; Vasodilation

1983
Substance P and capsaicin-induced contraction of human bronchi.
    Acta physiologica Scandinavica, 1983, Volume: 119, Issue:1

    Topics: Acetylcholine; Aged; Animals; Atropine; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Humans; Middle Aged; Muscle Contraction; Muscle, Smooth; Substance P; Tetrodotoxin

1983
Vascular protein linkage in various tissue induced by substance P, capsaicin, bradykinin, serotonin, histamine and by antigen challenge.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:3

    Topics: Animals; Antigens; Blood Proteins; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Substance P

1983
Effect of chemoreceptor and pulmonary receptor stimulation on dilator nares EMG activity in the dog.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1983, Volume: 91, Issue:6

    Topics: Animals; Capsaicin; Carbon Dioxide; Chemoreceptor Cells; Dogs; Electromyography; Facial Muscles; Histamine; Hypercapnia; Hypoxia; Mechanoreceptors; Nose; Pulmonary Stretch Receptors; Stimulation, Chemical

1983
Impaired thermoregulation against cold in capsaicin pretreated rats.
    Pflugers Archiv : European journal of physiology, 1983, Volume: 399, Issue:3

    Topics: Animals; Body Temperature Regulation; Capsaicin; Cold Temperature; Histamine; Hot Temperature; Male; Pentobarbital; Rats; Rats, Inbred Strains; Time Factors

1983
Capsaicin pretreatment inhibits vagal cholinergic and non-cholinergic control of pulmonary mechanics in the guinea pig.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Bronchi; Capsaicin; Choline O-Acetyltransferase; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lung Compliance; Male; Muscle Contraction; Muscle, Smooth; Receptors, Muscarinic; Respiratory Function Tests; Trachea; Vagus Nerve

1984
Increase in tissue concentrations of histamine and 5-hydroxytryptamine following capsaicin treatment of newborn rats.
    Life sciences, 1981, Sep-14, Volume: 29, Issue:11

    Topics: Animals; Animals, Newborn; Capsaicin; Fatty Acids, Unsaturated; Female; Histamine; Male; Mast Cells; Rats; Rats, Inbred Strains; Serotonin; Tissue Distribution

1981
Isbufylline, a new xanthine derivative, inhibits airway hyperresponsiveness and airway inflammation in guinea pigs.
    European journal of pharmacology, 1993, Nov-16, Volume: 249, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Albuterol; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Capsaicin; Dextrans; Dyspnea; Fluorescein-5-isothiocyanate; Guinea Pigs; Histamine; Leukocytes; Male; Ovalbumin; Platelet Activating Factor

1993
Ruthenium red selectively attenuates capsaicin induced vasodilation in pig nasal mucosa.
    Acta oto-laryngologica, 1994, Volume: 114, Issue:6

    Topics: Animals; Blood Pressure; Bradykinin; Calcium Channels; Capsaicin; Histamine; Nasal Cavity; Nasal Mucosa; Nicotine; Ruthenium Red; Swine; Vasodilation

1994
An investigation into the mechanism of capsaicin-induced oedema in rabbit skin.
    British journal of pharmacology, 1995, Volume: 114, Issue:3

    Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Catalase; Dexamethasone; Drug Interactions; Edema; Histamine; Indoles; Indomethacin; Injections, Intradermal; Injections, Intravenous; Isoindoles; Male; Piperidines; Rabbits; Regional Blood Flow; Ruthenium Red; Skin; Substance P; Vasodilator Agents

1995
Scratching behavior induced by pruritogenic but not algesiogenic agents in mice.
    European journal of pharmacology, 1995, Mar-14, Volume: 275, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Formaldehyde; Histamine; Male; Mice; p-Methoxy-N-methylphenethylamine; Pain; Pruritus; Substance P

1995
Substance P-induced histamine release in tracheally perfused guinea pig lungs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:4

    Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Mast Cells; Perfusion; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

1995
Inhibition by actinomycin D of neurogenic mouse ear oedema.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:3

    Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide

1995
Histamine-induced edema in the rat paw--effect of capsaicin denervation and a CGRP receptor antagonist.
    European journal of pharmacology, 1995, Jun-12, Volume: 279, Issue:2-3

    Topics: Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capillary Permeability; Capsaicin; Denervation; Edema; Foot; Histamine; Male; Miotics; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley

1995
Potentiation by viral respiratory infection of ovalbumin-induced guinea-pig tracheal hyperresponsiveness: role for tachykinins.
    British journal of pharmacology, 1995, Volume: 115, Issue:6

    Topics: Animals; Arecoline; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hypersensitivity; Male; Ovalbumin; Respiratory Tract Infections; Substance P; Tachykinins; Trachea; Virus Cultivation

1995
Effects of topical capsaicin in seasonal allergic rhinitis.
    Thorax, 1995, Volume: 50, Issue:3

    Topics: Administration, Topical; Adult; Allergens; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Female; Histamine; Humans; Male; Middle Aged; Nasal Mucosa; Pain; Pollen; Rhinitis, Allergic, Seasonal; Time Factors

1995
The pharmacological properties of FK888, a novel dipeptide NK1 antagonist.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Bronchoconstriction; Capsaicin; Cell Membrane; Dipeptides; Edema; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Indoles; Kinetics; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-1; Substance P

1993
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors.
    The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1

    Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

1993
Activation of capsaicin-sensitive sensory fibers modulates PAF-induced bronchial hyperresponsiveness in anesthetized guinea pigs.
    The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1

    Topics: Anesthesia; Animals; Azepines; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Nerve Fibers; Platelet Activating Factor; Ruthenium Red; Serum Albumin, Bovine; Time Factors; Triazoles

1993
Regulation of jejunal arterioles by capsaicin-sensitive nerves in Nippostrongylus brasiliensis-sensitized rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:1

    Topics: Animals; Arterioles; Capsaicin; Histamine; Jejunum; Male; Mast Cells; Neurons, Afferent; Nippostrongylus; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vasodilation

1995
An important role of tachykinins in ozone-induced airway hyperresponsiveness.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:6

    Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Capsaicin; Guinea Pigs; Histamine; Neutrophils; Ozone; Premedication; Tachykinins

1995
Changes in nasal airway resistance and secretory response in the guinea pig after nasal challenge with capsaicin and histamine.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1994, Volume: 251, Issue:4

    Topics: Administration, Intranasal; Airway Resistance; Aminophylline; Animals; Atropine; Capsaicin; Diphenhydramine; Dose-Response Relationship, Drug; Exudates and Transudates; Guinea Pigs; Hexamethonium; Histamine; Male; Nasal Mucosa; Neurons, Afferent; Nose; Terbutaline; Time Factors

1994
Effects of capsaicin on the airway responses to inhaled endotoxin in the guinea pig.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Administration, Inhalation; Airway Resistance; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Capsaicin; Endotoxins; Escherichia coli; Glycopeptides; Guinea Pigs; Histamine; Inflammation; Lipopolysaccharides; Macrophages; Male; Neprilysin; Neutrophils; Premedication; Propranolol; Trachea

1994
Mechanisms underlying enhanced responses of J receptors of cats to excitants in pulmonary oedema.
    The Journal of physiology, 1993, Volume: 471

    Topics: Alloxan; Animals; Biguanides; Bradykinin; Capillary Permeability; Capsaicin; Cats; Histamine; Lung Compliance; Nicotine; Phosgene; Pressure; Pulmonary Circulation; Pulmonary Edema; Sensory Receptor Cells; Serotonin

1993
Effects of capsaicin desensitization on nasal mucosal secretion in guinea pigs in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:2

    Topics: Albumins; Alkaline Phosphatase; Animals; Atropine; Capsaicin; Desensitization, Immunologic; Dimethyl Sulfoxide; Enzyme-Linked Immunosorbent Assay; Exudates and Transudates; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; Male; Methacholine Compounds; Nasal Lavage Fluid; Nasal Mucosa; Nociceptors

1993
Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Aerosols; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; Inflammation; Lung; Male; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Pulmonary Circulation; Receptors, Neurokinin-2; Vascular Resistance

1993
Effects of aerosol-applied capsaicin, histamine and prostaglandin E2 on airway sensory receptors of anaesthetized cats.
    The Journal of physiology, 1993, Volume: 469

    Topics: Administration, Inhalation; Anesthesia; Animals; Bronchoconstriction; Capsaicin; Cats; Dinoprostone; Histamine; Injections, Intravenous; Lung; Male; Mechanoreceptors; Nerve Fibers; Nerve Fibers, Myelinated; Neural Conduction; Respiration, Artificial; Respiratory Mechanics; Sensory Receptor Cells; Vagus Nerve

1993
Regulation of gastroduodenal bicarbonate secretion by capsaicin-sensitive sensory neurons in rats.
    Journal of clinical gastroenterology, 1993, Volume: 17 Suppl 1

    Topics: Afferent Pathways; Animals; Bicarbonates; Capsaicin; Denervation; Dose-Response Relationship, Drug; Duodenum; Gastric Acidity Determination; Gastric Mucosa; Histamine; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells

1993
Histamine enhances vagal pulmonary C-fiber responses to capsaicin and lung inflation.
    Respiration physiology, 1993, Volume: 93, Issue:1

    Topics: Action Potentials; Afferent Pathways; Animals; Capsaicin; Dogs; Drug Synergism; Histamine; Lung; Nerve Fibers; Pressure; Respiratory Mechanics; Vagus Nerve

1993
Inhibitory effects of capsazepine and SR 48968 on citric acid-induced bronchoconstriction in guinea-pigs.
    European journal of pharmacology, 1993, Jun-04, Volume: 236, Issue:3

    Topics: Administration, Inhalation; Analysis of Variance; Animals; Benzamides; Bronchoconstriction; Capsaicin; Citrates; Citric Acid; Female; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; Male; Neurokinin A; Neurons, Afferent; Piperidines

1993
The effect of neonatal capsaicin on the development of bronchial hyperresponsiveness in allergic rabbits.
    European journal of pharmacology, 1993, Feb-23, Volume: 232, Issue:1

    Topics: Animals; Animals, Newborn; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Electric Stimulation; Female; Histamine; Hypersensitivity; Male; Methacholine Chloride; Neuropeptides; Rabbits; Radioimmunoassay

1993
Appearance of airway absorption and exudation tracers in guinea pig tracheobronchial lymph nodes.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:2

    Topics: Absorption; Animals; Bradykinin; Bronchi; Capillaries; Capsaicin; Carbachol; Exudates and Transudates; Guinea Pigs; Histamine; Immunohistochemistry; Lymph Nodes; Male; Mucous Membrane; Nerve Fibers; Ovalbumin; Serum Albumin, Radio-Iodinated; Therapeutic Irrigation; Trachea

1993
Capsaicin pretreatment of guinea pigs in vivo prevents ovalbumin-induced tracheal hyperreactivity in vitro.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Aerosols; Analysis of Variance; Animals; Arecoline; Bronchial Hyperreactivity; Capsaicin; Guinea Pigs; Histamine; In Vitro Techniques; Male; Ovalbumin; Trachea

1993
Hypotensive effect of 13-hydroxylinoleic acid in the rat: mediation via the release of a CGRP-like mediator from capsaicin-sensitive nerves.
    British journal of pharmacology, 1995, Volume: 115, Issue:5

    Topics: Acetylcholine; Animals; Animals, Newborn; Blood Pressure; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Histamine; Leukotriene B4; Linoleic Acids; Male; Neurons; Neurons, Afferent; Nitroprusside; Rats; Rats, Wistar; Ruthenium Red

1995
Vagal cooling and the origin of pulmonary reflexes in cats.
    Advances in experimental medicine and biology, 1995, Volume: 393

    Topics: Animals; Capsaicin; Cats; Cold Temperature; Histamine; Lung; Reflex; Respiration; Tidal Volume; Vagus Nerve

1995
Histamine-induced end-tidal inspiratory activity and lung receptors in cats.
    The European respiratory journal, 1995, Volume: 8, Issue:12

    Topics: Animals; Capsaicin; Cats; Electromyography; Female; Histamine; Male; Mechanoreceptors; Nerve Fibers; Pulmonary Ventilation; Respiratory Muscles; Temperature; Vagotomy; Vagus Nerve; Ventilators, Negative-Pressure

1995
Intraplantar injection of nerve growth factor into the rat hind paw: local edema and effects on thermal nociceptive threshold.
    Pain, 1996, Volume: 64, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase Inhibitors; Denervation; Edema; Foot; Histamine; Injections; Male; Mast Cells; Nerve Growth Factors; Neurons, Afferent; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Substance P

1996
Involvement of NK2 receptors rather than NK1 receptors in bronchial hyperresponsiveness induced by allergic reaction in guinea-pigs.
    British journal of pharmacology, 1996, Volume: 117, Issue:3

    Topics: Animals; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Capsaicin; Dipeptides; Glycopeptides; Guinea Pigs; Histamine; Indoles; Male; Methacholine Chloride; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Protease Inhibitors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Respiratory Hypersensitivity

1996
Capsaicin-induced release of VIP-like immunoreactivity: modulation by enzyme inhibitors.
    The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 1

    Topics: Animals; Capsaicin; Guinea Pigs; Histamine; Male; Methacholine Chloride; Nerve Fibers; Neurotoxins; Protease Inhibitors; Thiorphan; Trypsin Inhibitors; Vasoactive Intestinal Peptide

1996
Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions.
    Neuroscience, 1997, Volume: 77, Issue:3

    Topics: Animals; Animals, Newborn; Capsaicin; Cerebral Cortex; Chymases; Denervation; Dura Mater; Enzyme-Linked Immunosorbent Assay; Histamine; Histamine Antagonists; Inflammation; Male; Mast Cells; Methylhistamines; Nerve Fibers; Neurons, Afferent; Nippostrongylus; Piperidines; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Serine Endopeptidases; Strongylida Infections

1997
Responses of rat spinal dorsal horn neurons to intracutaneous microinjection of histamine, capsaicin, and other irritants.
    Journal of neurophysiology, 1997, Volume: 77, Issue:5

    Topics: Afferent Pathways; Animals; Brain Mapping; Capsaicin; Chemoreceptor Cells; Dose-Response Relationship, Drug; Ethanol; Evoked Potentials; Ganglia, Spinal; Histamine; Injections; Irritants; Male; Nociceptors; Pain Threshold; Periaqueductal Gray; Psychophysics; Rats; Rats, Sprague-Dawley; Skin; Synaptic Transmission

1997
Involvement of tachykinins in endotoxin-induced airway hyperresponsiveness.
    Lung, 1997, Volume: 175, Issue:4

    Topics: Animals; Bronchi; Bronchial Hyperreactivity; Capsaicin; Escherichia coli; Guinea Pigs; Histamine; Lipopolysaccharides; Male; Nerve Fibers; Tachykinins

1997
The indomethacin-induced gastric mucosal damage in rats. Effect of gastric acid, acid inhibition, capsaicin-type agents and prostacyclin.
    Journal of physiology, Paris, 1997, Volume: 91, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diterpenes; Epoprostenol; Female; Gastric Acid; Gastric Mucosa; Histamine; Hydrochloric Acid; Indomethacin; Isoproterenol; Laser-Doppler Flowmetry; Male; Microcirculation; Neurotoxins; Pentagastrin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach Ulcer; Vasodilator Agents

1997
Sensory receptor activation by mediators of defense reflexes in guinea-pig lungs.
    Respiration physiology, 1997, Volume: 108, Issue:3

    Topics: Action Potentials; Aerosols; Animals; Bradykinin; Bronchoconstriction; Capsaicin; Female; Guinea Pigs; Histamine; Isoproterenol; Lung; Male; Nerve Fibers; Pressure; Respiration; Sensory Receptor Cells; Trachea

1997
Tachykinin antagonist FK224 inhibits neurokinin A-, substance P- and capsaicin-induced human bronchial contraction.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:3

    Topics: Acetylcholine; Adult; Aged; Bronchi; Capsaicin; Glycopeptides; Histamine; Humans; In Vitro Techniques; Leukotriene D4; Middle Aged; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Protease Inhibitors; Receptors, Tachykinin; Substance P; Tachykinins

1997
Synergistic interactions between neuropeptide and histamine on the capillary permeability in rat skin: evaluation by reflectance spectrophotometry.
    Microvascular research, 1997, Volume: 54, Issue:1

    Topics: Administration, Cutaneous; Animals; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Cimetidine; Diphenhydramine; Drug Synergism; Histamine; Histamine Antagonists; Male; Neuropeptides; Rats; Rats, Wistar; Skin; Spectrophotometry; Substance P

1997
Plasma extravasation and neuropeptide release in human skin as measured by intradermal microdialysis.
    Neuroscience letters, 1997, Jul-18, Volume: 230, Issue:2

    Topics: Adult; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Forearm; Histamine; Humans; Inflammation; Iontophoresis; Microdialysis; Pain; Skin; Substance P; Time Factors

1997
The effect of 15-HPETE on airway responsiveness and pulmonary cell recruitment in rabbits.
    British journal of pharmacology, 1997, Volume: 122, Issue:2

    Topics: Animals; Atropine; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Histamine; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Lung; Male; Muscarinic Antagonists; Rabbits

1997
Neurokinin A-LI release after antigen challenge in guinea-pig bronchial tubes: influence of histamine and bradykinin.
    British journal of pharmacology, 1997, Volume: 122, Issue:3

    Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Ovalbumin; Pyrilamine; Substance P; Trachea

1997
Central and peripheral effects of the non-neural substances on respiration before and after vagotomy.
    The Tohoku journal of experimental medicine, 1997, Volume: 182, Issue:4

    Topics: Animals; Blood Pressure; Bradykinin; Capsaicin; Central Nervous System; Dogs; Histamine; Nerve Fibers; Peripheral Nervous System; Pulmonary Stretch Receptors; Respiratory Function Tests; Respiratory Mechanics; Vagotomy; Veratridine

1997
Effects of inhaled histamine, methacholine and capsaicin on sputum levels of alpha 2-macroglobulin.
    Thorax, 1997, Volume: 52, Issue:11

    Topics: Administration, Inhalation; Adult; Aerosols; alpha-Macroglobulins; Bronchial Provocation Tests; Bronchoconstrictor Agents; Capsaicin; Female; Histamine; Humans; Male; Methacholine Chloride; Sputum; Statistics, Nonparametric

1997
Role of substance P in experimental allergic conjunctivitis in guinea pigs.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:9

    Topics: Animals; Capillary Permeability; Capsaicin; Conjunctiva; Conjunctivitis, Allergic; Dipeptides; Disease Models, Animal; Guinea Pigs; Histamine; Indoles; Male; Mast Cells; Ovalbumin; p-Methoxy-N-methylphenethylamine; Serine Proteinase Inhibitors; Substance P; Tears

1997
Effects of carbamazepine on plasma extravasation and bronchoconstriction induced by substance P, capsaicin, acetaldehyde and histamine in guinea-pig lower airways.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:1

    Topics: Acetaldehyde; Animals; Anticonvulsants; Bronchoconstriction; Capillary Permeability; Capsaicin; Carbamazepine; Evans Blue; Guinea Pigs; Histamine; Male; Pharmaceutical Preparations; Receptors, Neurokinin-1; Substance P; Trachea

1998
Role of sensory innervation and mast cells in neurogenic plasma protein exudation into the airway lumen.
    Respirology (Carlton, Vic.), 1997, Volume: 2, Issue:4

    Topics: Analysis of Variance; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Capillary Permeability; Capsaicin; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Exudates and Transudates; Histamine; Inflammation; Mast Cells; Neuropeptides; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Substance P; Trachea; Vagus Nerve

1997
Activation of neurons in rat trigeminal subnucleus caudalis by different irritant chemicals applied to oral or ocular mucosa.
    Journal of neurophysiology, 1998, Volume: 80, Issue:2

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzodioxoles; Capsaicin; Conjunctiva; Cornea; Dose-Response Relationship, Drug; Electrophysiology; Ethanol; Ganglionic Stimulants; Histamine; Irritants; Male; Mouth Mucosa; Mustard Plant; Neurons; Nicotine; Piperidines; Plant Extracts; Plant Oils; Polyunsaturated Alkamides; Rats; Rats, Wistar; Reaction Time; Serotonin; Sodium Chloride; Solvents; Stimulation, Chemical; Tachyphylaxis; Tongue; Trigeminal Nuclei

1998
Effects of S-salbutamol on human isolated bronchus.
    Pulmonary pharmacology & therapeutics, 1998, Volume: 11, Issue:1

    Topics: Adenosine; Albuterol; Bradykinin; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene C4; Methacholine Chloride; Platelet Activating Factor

1998
Endothelin-1 and bronchial hyperresponsiveness in the rabbit.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:5

    Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Capsaicin; Dose-Response Relationship, Drug; Endothelin-1; Eosinophils; Female; Histamine; Leukocyte Count; Leukocytes, Mononuclear; Lung; Male; Neutrophils; Rabbits

1998
Hyperosmolar saline induces airway resistance changes and neuropeptide release: a comparison with the effect of capsaicin, potassium and histamine.
    European journal of clinical investigation, 1999, Volume: 29, Issue:3

    Topics: Airway Resistance; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Histamine; Neurokinin A; Nitric Oxide; Potassium; Saline Solution, Hypertonic

1999
Response properties of trigeminal brain stem neurons with input from dura mater encephali in the rat.
    Neuroscience, 1999, Volume: 90, Issue:2

    Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Dura Mater; Electric Stimulation; Histamine; Inflammation; Male; Mechanoreceptors; Microelectrodes; Neurons; Rats; Rats, Wistar; Serotonin; Trigeminal Nuclei; Trigeminal Nucleus, Spinal

1999
Inflammatory effect of intratracheal instillation of ultrafine particles in the rabbit: role of C-fiber and mast cells.
    Toxicology and applied pharmacology, 1999, Nov-01, Volume: 160, Issue:3

    Topics: Animals; Capsaicin; Carbachol; Chemotaxis, Leukocyte; Female; Histamine; Histamine Antagonists; Intubation, Intratracheal; Lung; Male; Mast Cells; Microspheres; Nerve Fibers; Neutrophils; p-Methoxy-N-methylphenethylamine; Pneumonia; Polystyrenes; Rabbits; Receptors, Tachykinin; Substance P; Thiorphan

1999
The role of protease-activated receptor-2 (PAR2) in the modulation of beating of the mouse isolated ureter: lack of involvement of mast cells or sensory nerves.
    British journal of pharmacology, 1999, Volume: 128, Issue:4

    Topics: Animals; Capsaicin; Histamine; Immunohistochemistry; In Vitro Techniques; Indomethacin; Male; Mast Cells; Mice; Mice, Inbred BALB C; Neurons, Afferent; Nitroarginine; Oligopeptides; Receptor, PAR-2; Receptors, Thrombin; Trypsin; Ureter

1999
Capsaicin sensitivity and voltage-gated sodium currents in colon sensory neurons from rat dorsal root ganglia.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Action Potentials; Adenosine; Analgesics; Animals; Bradykinin; Capsaicin; Carbocyanines; Colon; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Fluorescent Dyes; Ganglia, Spinal; Histamine; Ion Channel Gating; Male; Neurons, Afferent; Pain; Rats; Rats, Sprague-Dawley; Serotonin; Sodium; Sodium Channels; Tetrodotoxin

1999
Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice.
    Neuroscience research, 1999, Volume: 35, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Capsaicin; Dose-Response Relationship, Drug; Histamine; Injections, Intradermal; Male; Mice; Mice, Inbred Strains; Naloxone; Narcotic Antagonists; Pruritus; Reaction Time; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1999
Involvement of vanilloid receptors and purinoceptors in the Phoneutria nigriventer spider venom-induced plasma extravasation in rat skin.
    European journal of pharmacology, 2000, Mar-17, Volume: 391, Issue:3

    Topics: Animals; Blood Proteins; Capillary Permeability; Capsaicin; Female; Histamine; Male; Mast Cells; Neurons, Afferent; Neuropeptides; Nucleotides; Peritoneal Cavity; Rats; Rats, Wistar; Receptors, Drug; Receptors, Purinergic; Serotonin; Spider Venoms

2000
Involvement of glutamate in transmission of afferent constrictive inputs from the airways to the nucleus tractus solitarius in ferrets.
    Journal of the autonomic nervous system, 2000, Apr-12, Volume: 80, Issue:1-2

    Topics: Aerosols; Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Ferrets; Glutamic Acid; Heart Rate; Histamine; Lung; Male; Microdialysis; Neurons, Afferent; Oxygen; Parasympathetic Nervous System; Proto-Oncogene Proteins c-fos; Receptors, AMPA; Reflex; Respiration; Solitary Nucleus; Synaptic Transmission

2000
Superficial dorsal horn neurons identified by intracutaneous histamine: chemonociceptive responses and modulation by morphine.
    Journal of neurophysiology, 2000, Volume: 84, Issue:2

    Topics: Analgesics, Opioid; Animals; Capsaicin; Electrophysiology; Ganglionic Stimulants; Histamine; Hot Temperature; Injections, Intradermal; Irritants; Male; Morphine; Nicotine; Nociceptors; Posterior Horn Cells; Pruritus; Rats; Rats, Sprague-Dawley; Reaction Time; Stimulation, Chemical; Tachyphylaxis

2000
CNS induced neurogenic cystitis is associated with bladder mast cell degranulation in the rat.
    The Journal of urology, 2000, Volume: 164, Issue:3 Pt 1

    Topics: Administration, Intravesical; Analysis of Variance; Animals; Capsaicin; Cell Degranulation; Central Nervous System Viral Diseases; Cystitis; Denervation; Disease Models, Animal; Diterpenes; Histamine; Male; Mast Cells; Neurogenic Inflammation; Neurons, Afferent; Neurotoxins; Pseudorabies; Rats; Rats, Sprague-Dawley; Urinary Bladder

2000
A neural pathway for itch.
    Nature neuroscience, 2001, Volume: 4, Issue:1

    Topics: Afferent Pathways; Animals; Capsaicin; Cats; Histamine; Humans; Posterior Horn Cells; Pruritus; Spinothalamic Tracts; Stimulation, Chemical; Thalamus

2001
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 90, Issue:2

    Topics: Administration, Inhalation; Airway Resistance; Animals; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Guinea Pigs; Histamine; Leukocyte Count; Lung; Male; Methacholine Chloride; Neurokinin A; Ovalbumin; Peptide Fragments; Smoking; Substance P; Wakefulness

2001
Effect of ricinoleic acid in acute and subchronic experimental models of inflammation.
    Mediators of inflammation, 2000, Volume: 9, Issue:5

    Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Chronic Disease; Disease Models, Animal; Edema; Eyelid Diseases; Eyelids; Freund's Adjuvant; Guinea Pigs; Histamine; Injections, Intradermal; Male; Ricinoleic Acids

2000
Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Adenosine; Allergens; Animals; Atropine; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Capsaicin; Cardiovascular System; Cell Degranulation; Cromolyn Sodium; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Ketanserin; Lung; Male; Mast Cells; Methacholine Chloride; Methysergide; Ovalbumin; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred BN; Respiratory Hypersensitivity; Serotonin; Serotonin Antagonists; Time Factors; Vagotomy; Vasoconstrictor Agents

2001
Chronic tobacco smoke exposure increases cough to capsaicin in awake guinea pigs.
    Respiration physiology, 2001, Volume: 126, Issue:2

    Topics: Aerosols; Animals; Bradykinin; Bronchoalveolar Lavage Fluid; Capsaicin; Chronic Disease; Cough; Guinea Pigs; Histamine; Irritants; Methacholine Chloride; Respiratory Physiological Phenomena; Smoking; Trachea

2001
Histamine H1 receptor mRNA is expressed in capsaicin-insensitive sensory neurons with neuropeptide Y-immunoreactivity in guinea pigs.
    Brain research, 2001, May-18, Volume: 901, Issue:1-2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Ganglia, Spinal; Guinea Pigs; Histamine; Immunohistochemistry; Male; Nerve Fibers; Neurons, Afferent; Neuropeptide Y; Nociceptors; Pain; Posterior Horn Cells; Receptors, Histamine H1; RNA, Messenger

2001
Airway hyperresponsiveness to bronchoconstrictor challenge after wood smoke exposure in guinea pigs.
    Life sciences, 2001, May-18, Volume: 68, Issue:26

    Topics: Acetylcholine; Airway Resistance; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Capsaicin; Dinoprost; Guinea Pigs; Histamine; Injections, Intravenous; Lung; Male; Respiratory Mechanics; Smoke; Substance P; Wood

2001
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
    British journal of pharmacology, 2001, Volume: 133, Issue:6

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation

2001
Modulatory effect of two novel CGRP receptor antagonists on nasal vasodilatatory responses to exogenous CGRP, capsaicin, bradykinin and histamine in anaesthetised pigs.
    Regulatory peptides, 2001, Sep-15, Volume: 101, Issue:1-3

    Topics: Anesthesia; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Dose-Response Relationship, Drug; Female; Histamine; Infusions, Intra-Arterial; Male; Nasal Mucosa; Neurogenic Inflammation; Peptide Fragments; Swine; Time Factors; Vasodilation

2001
Roles of mast cells and sensory nerves in cutaneous vascular hyperpermeability and scratching behavior induced by poly-L-arginine in rats.
    European journal of pharmacology, 2001, Aug-17, Volume: 425, Issue:3

    Topics: Animals; Behavior, Animal; Capillary Permeability; Capsaicin; Chlorpheniramine; Dose-Response Relationship, Drug; Glycopeptides; Histamine; Histamine H1 Antagonists; Indoles; Injections, Intradermal; Male; Mast Cells; Methysergide; Neurons, Afferent; Peptides; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Skin; Substance P

2001
Capsaicin-evoked CGRP release from rat buccal mucosa: development of a model system for studying trigeminal mechanisms of neurogenic inflammation.
    The European journal of neuroscience, 2001, Volume: 14, Issue:7

    Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Inflammation Mediators; Ionophores; Male; Mouth Mucosa; Neurogenic Inflammation; Nociceptors; Organ Culture Techniques; Pain Measurement; Potassium Chloride; Rats; Rats, Sprague-Dawley; Serotonin; Trigeminal Nerve

2001
Multiple mechanisms of reflex bronchospasm in guinea pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:6

    Topics: Animals; Bradykinin; Bronchi; Bronchial Spasm; Capsaicin; Guinea Pigs; Histamine; Insufflation; Lung; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nervous System; Pressure; Pulmonary Circulation; Reflex; Respiratory Mechanics; Tachykinins; Trachea; Vasodilation

2001
ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation.
    European journal of pharmacology, 2002, Jan-18, Volume: 435, Issue:1

    Topics: Animals; Benzoquinones; Binding Sites; Calcitonin Gene-Related Peptide; Calcium; Calcium Channels; Capsaicin; Carrageenan; Central Nervous System; CHO Cells; Cricetinae; Disease Models, Animal; Edema; Extravasation of Diagnostic and Therapeutic Materials; Gene Expression; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Mice; Neurogenic Inflammation; Pain; Pain Measurement; Piperidines; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Species Specificity; Spinal Cord; Transfection; Tritium

2002
Responses of superficial dorsal horn neurons to intradermal serotonin and other irritants: comparison with scratching behavior.
    Journal of neurophysiology, 2002, Volume: 87, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Disinfectants; Electrophysiology; Formaldehyde; Histamine; Injections, Intradermal; Irritants; Male; Pain; Posterior Horn Cells; Pruritus; Rats; Rats, Sprague-Dawley; Serotonin

2002
The involvement of sensory neuropeptides in airway hyper-responsiveness in rabbits sensitized and challenged to Parietaria judaica.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:3

    Topics: Aerosols; Allergens; Animals; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Female; Glycoproteins; Histamine; Immunization; Lung; Male; Models, Animal; Neuropeptides; Plant Proteins; Rabbits; Receptors, Tachykinin; Respiratory Hypersensitivity

2002
Evidence for differential reflex regulation of cholinergic and noncholinergic parasympathetic nerves innervating the airways.
    American journal of respiratory and critical care medicine, 2002, Apr-15, Volume: 165, Issue:8

    Topics: Animals; Capsaicin; Cholinergic Fibers; Guinea Pigs; Histamine; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympathetic Fibers, Postganglionic; Parasympathetic Nervous System; Reflex; Trachea; Vagus Nerve

2002
Characterisation of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones.
    Neuroscience, 2002, Volume: 110, Issue:2

    Topics: Animals; Calcium; Calcium Signaling; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Histamine; Histamine Antagonists; Nerve Fibers; Neurons, Afferent; Nociceptors; Pruritus; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Receptors, Serotonin; Ryanodine Receptor Calcium Release Channel; Serotonin Antagonists; Type C Phospholipases

2002
Tobacco smoke exposure and bombesin-like peptides in guinea pigs.
    Peptides, 2002, Volume: 23, Issue:5

    Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Body Weight; Bombesin; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Gastrin-Releasing Peptide; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Ovalbumin; Perfusion; Plethysmography, Whole Body; Radioimmunoassay; Respiratory Hypersensitivity; Serotonin; Smoking; Trachea

2002
Pharmacological profile of (2R-trans)-4-[1-[3,5-bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an orally and centrally active neurokinin-1 receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2

    Topics: Administration, Oral; Allergens; Animals; Butanols; Capsaicin; Cats; Dogs; Edema; Ferrets; Gerbillinae; Guinea Pigs; Histamine; Kinetics; Malates; Mice; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Platelet Activating Factor; Rabbits; Receptors, Neurokinin-1; Salivation; Substance P; Time Factors

2002
Histamine is involved in gastric vasodilation during acid back diffusion via activation of sensory neurons.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:3

    Topics: Animals; Capsaicin; Cell Degranulation; Diffusion; Gastric Acid; Gastric Mucosa; Histamine; Male; Mast Cells; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Vasodilation

2002
Production of acute and chronic itch with histamine and contact sensitizers in the mouse and guinea pig.
    Experimental dermatology, 2002, Volume: 11, Issue:4

    Topics: Acute Disease; Animals; Capsaicin; Chronic Disease; Dinitrochlorobenzene; Disease Models, Animal; Female; Guinea Pigs; Haptens; Histamine; Iontophoresis; Male; Mice; Mice, Inbred BALB C; Naloxone; Pruritus

2002
Ultralow doses of antibodies to inflammatory mediators: antitussive properties of antibodies to bradykinin, histamine, and serotonin.
    Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7

    Topics: Animals; Antibodies; Antitussive Agents; Bradykinin; Capsaicin; Citric Acid; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Humans; Male; Serotonin

2003
Comparison of responses of primate spinothalamic tract neurons to pruritic and algogenic stimuli.
    Journal of neurophysiology, 2004, Volume: 91, Issue:1

    Topics: Action Potentials; Analysis of Variance; Animals; Capsaicin; Electrophysiology; Evoked Potentials; Histamine; Hot Temperature; Hyperalgesia; Injections, Intradermal; Laminectomy; Macaca fascicularis; Physical Stimulation; Posterior Horn Cells; Pruritus; Reaction Time; Skin; Spinothalamic Tracts; Stimulation, Chemical; Thalamus; Time Factors

2004
Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs.
    The Journal of physiology, 2004, Jun-01, Volume: 557, Issue:Pt 2

    Topics: Anesthesia; Animals; Bradykinin; Capsaicin; Citric Acid; Cough; Electric Stimulation; Electrophysiology; Guinea Pigs; Histamine; Laryngeal Nerves; Male; Mechanoreceptors; Neurons, Afferent; Nodose Ganglion; Respiration; Stimulation, Chemical; Trachea

2004
Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons.
    Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3

    Topics: Animals; Calcium; Calcium Signaling; Capsaicin; Cells, Cultured; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Ganglia, Spinal; Histamine; Lipoxygenase; Neurons, Afferent; Nociceptors; Phospholipases A; Pruritus; Rats; Receptors, Drug

2004
Involvement of substance P, CGRP and histamine in the hyperalgesia and cytokine upregulation induced by intraplantar injection of capsaicin in rats.
    Journal of neuroimmunology, 2004, Volume: 153, Issue:1-2

    Topics: Analgesics; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Antagonists; Hyperalgesia; Injections, Spinal; Nerve Growth Factor; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Substance P; Time Factors; Up-Regulation

2004
Effect of capsaicin and histamine on heat regulation.
    Archives internationales de pharmacodynamie et de therapie, 1950, Volume: 81, Issue:1

    Topics: Capsaicin; Histamine; Hot Temperature; Humans

1950
Effect of histamine, capsaicine and procaine on heat-regulation.
    Archives internationales de pharmacodynamie et de therapie, 1950, Jul-01, Volume: 83, Issue:2

    Topics: Capsaicin; Histamine; Hot Temperature; Humans; Procaine

1950
Modulation of experimentally-induced cough by stimulation of nasal mucosa in cats and guinea pigs.
    Respiratory physiology & neurobiology, 2004, Sep-15, Volume: 142, Issue:2-3

    Topics: Animals; Blood Pressure; Capsaicin; Cats; Cough; Guinea Pigs; Histamine; Nasal Mucosa; Neurons, Afferent; Physical Stimulation; Respiration; Species Specificity; Stimulation, Chemical; Tidal Volume; Time Factors; Wakefulness

2004
Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Animals; Capsaicin; DNA; Gastric Mucosa; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Immersion; Interleukin-1; Male; Neurons, Afferent; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Regional Blood Flow; Restraint, Physical; Stomach Ulcer; Stress, Physiological

2005
Secretoneurin is released into human airways by topical histamine but not capsaicin.
    Allergy, 2005, Volume: 60, Issue:4

    Topics: Administration, Topical; Adult; Bronchi; Bronchial Provocation Tests; Capsaicin; Fucose; Histamine; Humans; Nasal Mucosa; Nasal Provocation Tests; Nervous System; Neuropeptides; Reference Values; Respiratory Mucosa; Secretogranin II; Tissue Distribution

2005
Airway inflammation and cough sensitivity in cough-variant asthma.
    Allergy, 2005, Volume: 60, Issue:11

    Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Capsaicin; Cell Count; Diagnosis, Differential; Female; Histamine; Humans; Inflammation; Interleukin-5; Male; Nitric Oxide; Sputum

2005
Intrathecally-administered histamine facilitates nociception through tachykinin NK1 and histamine H1 receptors: a study in histidine decarboxylase gene knockout mice.
    European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3

    Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Behavior, Animal; Capsaicin; Excitatory Amino Acid Antagonists; Female; Formaldehyde; Histamine; Histidine Decarboxylase; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Histamine H1; Receptors, Neurokinin-1; Substance P; Time Factors

2005
Nasal sensory nerve populations responding to histamine and capsaicin.
    The Journal of allergy and clinical immunology, 2005, Volume: 116, Issue:6

    Topics: Animals; Capsaicin; Cricetinae; Histamine; Histamine H1 Antagonists; Male; Nasal Mucosa; Substance P; Trigeminal Nerve

2005
Mechanisms underlying the relaxation induced by isokaempferide from Amburana cearensis in the guinea-pig isolated trachea.
    Life sciences, 2006, May-30, Volume: 79, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Capsaicin; Carbachol; Coumarins; Enzyme Inhibitors; Flavonoids; Guanylate Cyclase; Guinea Pigs; Histamine; In Vitro Techniques; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Plant Bark; Plant Extracts; Plants; Potassium Channel Blockers; Potassium Chloride; Trachea

2006
Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:3

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Atropine; Bronchi; Bronchodilator Agents; Capsaicin; Cholinergic Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histamine; Humans; In Vitro Techniques; Indomethacin; Leukotriene D4; Molecular Structure; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Peptides; Potassium Channels, Calcium-Activated; Propranolol; Prostaglandin D2; TRPV Cation Channels; Vasodilator Agents

2007
Capsaicin inhibits catecholamine secretion and synthesis by blocking Na+ and Ca2+ influx through a vanilloid receptor-independent pathway in bovine adrenal medullary cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:2

    Topics: Adrenal Medulla; Analgesics, Non-Narcotic; Animals; Benzaldehydes; Calcium; Calcium Radioisotopes; Capsaicin; Carbachol; Catecholamines; Cattle; Cells, Cultured; Cholinergic Agonists; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Histamine; Ion Transport; Ruthenium Red; Signal Transduction; Sodium; Sodium Radioisotopes; TRPV Cation Channels; Tyrosine 3-Monooxygenase; Veratridine

2006
Involvement of substance P and neurogenic inflammation in arsenic-induced early vascular dysfunction.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:1

    Topics: Analgesics; Animals; Arsenites; Capillary Permeability; Capsaicin; Ear; Endothelium, Vascular; Environmental Pollutants; Histamine; Histamine H1 Antagonists; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Pyrilamine; Receptors, Neurokinin-1; Skin; Sodium Compounds; Substance P; Time Factors

2007
TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Feb-28, Volume: 27, Issue:9

    Topics: Animals; Arachidonate 12-Lipoxygenase; Calcium; Capsaicin; Cells, Cultured; Enzyme Activation; Ganglia, Spinal; Histamine; Mice; Mice, Inbred C57BL; Neurons; Phospholipases A; Phospholipases A2; Rats; TRPV Cation Channels

2007
Psychophysical and physiological evidence for parallel afferent pathways mediating the sensation of itch.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jul-11, Volume: 27, Issue:28

    Topics: Administration, Topical; Adult; Afferent Pathways; Capsaicin; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Mucuna; Nerve Fibers; Nerve Fibers, Unmyelinated; Neurons, Afferent; Plant Structures; Pruritus; Psychophysics; Skin; Vasodilation

2007
Effect of TRFK-5 on airway responsiveness in ovalbumin-treated guinea pigs exposed to tobacco smoke.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2007, Volume: 44, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Bronchial Hyperreactivity; Capsaicin; Cell Movement; Disease Models, Animal; Eosinophils; Guinea Pigs; Histamine; Interleukin-5; Male; Methacholine Chloride; Ovalbumin; Tobacco Smoke Pollution

2007
Loss of capsaicin-induced meningeal neurogenic sensory vasodilatation in diabetic rats.
    Neuroscience, 2007, Nov-30, Volume: 150, Issue:1

    Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Dura Mater; Histamine; In Vitro Techniques; Insulin; Laser-Doppler Flowmetry; Male; Nerve Fibers; Rats; Rats, Wistar; Regional Blood Flow; Time Factors; TRPV Cation Channels; Vasodilation

2007
Effects of topical application of tacrolimus on acute itch-associated responses in mice.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:4

    Topics: Administration, Topical; Aedes; Animals; Antipruritics; Behavior, Animal; Capsaicin; Female; Histamine; Immunosuppressive Agents; Male; Mice; Mice, Inbred ICR; Pruritus; Serotonin; Substance P; Tacrolimus

2008
Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs.
    International immunopharmacology, 2008, Volume: 8, Issue:5

    Topics: Administration, Inhalation; Anesthetics, Local; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cough; Eosinophils; Guinea Pigs; Histamine; Inflammation; Lidocaine; Lung; Male; Ovalbumin; Substance P

2008
Leukotriene D4 increases the excitability of capsaicin-sensitive nasal sensory nerves to electrical and chemical stimuli.
    British journal of pharmacology, 2008, Volume: 154, Issue:6

    Topics: Animals; Calcium; Capsaicin; Electric Stimulation; Electrophysiology; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene D4; Male; Nasal Mucosa; Patch-Clamp Techniques; Receptors, Leukotriene; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensory Receptor Cells; Stimulation, Chemical; Trigeminal Nerve

2008
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
    International immunopharmacology, 2008, Volume: 8, Issue:8

    Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Imidazoles; Mice; Mice, Inbred BALB C; Ovalbumin; Piperidines; Pyrrolidines; Receptors, Histamine H3; Rhinitis, Allergic, Perennial; Substance P; Thiourea

2008
Separate peripheral pathways for pruritus in man.
    Journal of neurophysiology, 2008, Volume: 100, Issue:4

    Topics: Capsaicin; Electric Stimulation; Electrophysiology; Histamine; Hot Temperature; Humans; Mechanoreceptors; Mucuna; Nerve Fibers, Unmyelinated; Neural Pathways; Neurons, Afferent; Pain; Peripheral Nerves; Physical Stimulation; Pruritus; Psychophysics; Skin; Stimulation, Chemical

2008
A role for polymodal C-fiber afferents in nonhistaminergic itch.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Jul-23, Volume: 28, Issue:30

    Topics: Afferent Pathways; Animals; Behavior, Animal; Capsaicin; Dose-Response Relationship, Drug; Histamine; Injections, Intradermal; Macaca fascicularis; Nerve Fibers, Unmyelinated; Neural Conduction; Nociceptors; Pain Measurement; Physical Stimulation; Pruritus; Reaction Time; Sensory Thresholds; Skin; Stimulation, Chemical

2008
Residual spinothalamic tract pathways predict development of central pain after spinal cord injury.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 9

    Topics: Adult; Capsaicin; Cold Temperature; Female; Histamine; Hot Temperature; Humans; Male; Menthol; Middle Aged; Nerve Fibers; Neuralgia; Nociceptors; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Prognosis; Sensation; Spinal Cord Injuries; Spinothalamic Tracts

2008
Differential effects of airway afferent nerve subtypes on cough and respiration in anesthetized guinea pigs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:5

    Topics: Administration, Inhalation; Anesthesia; Animals; Capsaicin; Citric Acid; Cough; Guinea Pigs; Histamine; Hypertonic Solutions; Injections, Intra-Arterial; Injections, Intravenous; Larynx; Lung; Male; Nasal Mucosa; Neurons, Afferent; Reflex; Respiratory Mechanics; Respiratory System; Trachea; Vagotomy

2008
Behavioral differentiation between itch and pain in mouse.
    Pain, 2008, Oct-31, Volume: 139, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Cheek; Dose-Response Relationship, Drug; Forelimb; Hindlimb; Histamine; Male; Mice; Pain; Pruritus

2008
Tumor bearing decreases systemic acute inflammation in rats--role of mast cell degranulation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2009, Volume: 58, Issue:5

    Topics: Animals; Bradykinin; Capillary Permeability; Capsaicin; Carrageenan; Cell Degranulation; Dextrans; Edema; Histamine; Inflammation; Mast Cells; Neoplasm Transplantation; Neoplasms; Neutrophil Activation; Neutrophil Infiltration; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Substance P

2009
The GABAA agonist muscimol attenuates induced airway constriction in guinea pigs in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:4

    Topics: Acetylcholine; Airway Obstruction; Animals; Autonomic Nervous System; Capsaicin; Constriction, Pathologic; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Guanethidine; Guinea Pigs; Histamine; Male; Muscimol; Muscle, Smooth; Parasympathetic Nervous System; Pyridazines; Sympathetic Fibers, Postganglionic; Sympatholytics; Vagus Nerve

2009
Scratching behavior and Fos expression in superficial dorsal horn elicited by protease-activated receptor agonists and other itch mediators in mice.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Histamine; Injections, Intradermal; Mice; Morphine; Naltrexone; Oligopeptides; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pruritus; Receptor, PAR-2; Receptors, Opioid, mu; Receptors, Proteinase-Activated; Serotonin; Spinal Cord; Tachyphylaxis

2009
The effect and mechanism of action of capsaicin on gastric acid output.
    Journal of gastroenterology, 2009, Volume: 44, Issue:5

    Topics: Animals; Benzodiazepines; Bethanechol; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastrins; Histamine; Histamine H2 Antagonists; Hormone Antagonists; In Vitro Techniques; Male; Muscarinic Agonists; Rats; Rats, Wistar; Somatostatin; Stomach; Vagus Nerve

2009
Excitation of mouse superficial dorsal horn neurons by histamine and/or PAR-2 agonist: potential role in itch.
    Journal of neurophysiology, 2009, Volume: 102, Issue:4

    Topics: Action Potentials; Animals; Capsaicin; Cold Temperature; Histamine; Hot Temperature; Male; Mice; Mice, Inbred ICR; Mustard Plant; Neurons; Oligopeptides; Physical Stimulation; Plant Oils; Posterior Horn Cells; Pruritus; Receptor, PAR-2

2009
Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.
    Cell, 2009, Dec-24, Volume: 139, Issue:7

    Topics: Animals; Capsaicin; Chloroquine; Ganglia, Spinal; Histamine; Humans; Mice; Pruritus; Receptors, G-Protein-Coupled; Sensory Receptor Cells

2009
Role of attentional focus on bodily sensations in sensitivity to itch and pain.
    Acta dermato-venereologica, 2010, Volume: 90, Issue:1

    Topics: Administration, Topical; Adult; Attention; Capsaicin; Cold Temperature; Electric Stimulation; Female; Histamine; Humans; Iontophoresis; Middle Aged; Pain; Pain Measurement; Pain Threshold; Perception; Personality; Physical Stimulation; Pruritus; Sensory Thresholds; Surveys and Questionnaires; Young Adult

2010
Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch.
    Pain, 2010, Volume: 151, Issue:2

    Topics: Animals; Antibodies; Behavior, Animal; Calcium; Capsaicin; Disease Models, Animal; Ganglia, Spinal; Histamine; Ketanserin; Mice; Mice, Inbred ICR; Oligopeptides; Pruritus; Receptor, PAR-2; Sensory Receptor Cells; Serotonin; Serotonin Antagonists

2010
Facial injections of pruritogens and algogens excite partly overlapping populations of primary and second-order trigeminal neurons in mice.
    Journal of neurophysiology, 2010, Volume: 104, Issue:5

    Topics: Action Potentials; Animals; Capsaicin; Electrophysiology; Histamine; Male; Mice; Mice, Inbred ICR; Microinjections; Neurons; Oligopeptides; Pruritus; Sensory Receptor Cells; Serotonin; Trigeminal Ganglion

2010
Differential itch- and pain-related behavioral responses and µ-opoid modulation in mice.
    Acta dermato-venereologica, 2010, Volume: 90, Issue:6

    Topics: Analgesics, Opioid; Animals; Antigens, Plant; Behavior, Animal; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Injections, Intradermal; Irritants; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Mucuna; Naltrexone; Narcotic Antagonists; Pain; Pruritus; Receptor, PAR-2; Receptors, Opioid, mu; Receptors, Thrombin; Time Factors

2010
Role of transient receptor potential ankyrin subfamily member 1 in pruritus induced by endothelin-1.
    Neuroscience letters, 2011, Apr-04, Volume: 492, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Endothelin-1; Enzyme Inhibitors; Histamine; Irritants; Male; Mice; Mice, Inbred C57BL; Pruritus; Ruthenium Red; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2011
Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux.
    Respirology (Carlton, Vic.), 2011, Volume: 16, Issue:4

    Topics: Adult; Aged; Asthma; Capsaicin; Chronic Disease; Cough; Cross-Sectional Studies; Female; Gastroesophageal Reflux; Histamine; Humans; Male; Middle Aged; Prospective Studies; Prostaglandin D2; Reflex; Respiratory Function Tests; Sputum; Substance P; Tryptases

2011
Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model.
    Journal of neurophysiology, 2011, Volume: 105, Issue:6

    Topics: Acetone; Action Potentials; Analysis of Variance; Animals; Antipruritics; Capsaicin; Disease Models, Animal; Drug Synergism; Functional Laterality; Histamine; Isothiocyanates; Mice; Models, Biological; Oligopeptides; Physical Stimulation; Posterior Horn Cells; Pruritus; Receptors, Proteinase-Activated; Serotonin; Solvents; Spinal Cord; Water

2011
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
    Nature neuroscience, 2011, Volume: 14, Issue:5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antirheumatic Agents; Calcium; Capsaicin; Cells, Cultured; Chloroquine; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Histamine; Membrane Potentials; Mice; Mice, Knockout; Mustard Plant; Neuroblastoma; Patch-Clamp Techniques; Peptides; Plant Oils; Pruritus; Receptors, G-Protein-Coupled; Sensory Receptor Cells; Signal Transduction; Time Factors; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel

2011
Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.
    Pain, 2011, Volume: 152, Issue:8

    Topics: Acrylamides; Anilides; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antioxidants; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cinnamates; Cromolyn Sodium; Disease Models, Animal; Diterpenes; Edema; Gabexate; Histamine; Male; Mast Cells; Methysergide; Pain; Promethazine; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Serotonin; Serotonin Antagonists; Tritium; TRPV Cation Channels; Uric Acid

2011
Dissecting itch and pain sensations in human skin.
    Pain, 2011, Volume: 152, Issue:11

    Topics: Acute Pain; Capsaicin; Female; Histamine; Humans; Hyperalgesia; Male; Skin

2011
A role for nociceptive, myelinated nerve fibers in itch sensation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Oct-19, Volume: 31, Issue:42

    Topics: Action Potentials; Animals; Area Under Curve; Biophysics; Capsaicin; Electric Stimulation; Female; Histamine; Humans; Macaca fascicularis; Male; Mucuna; Nerve Fibers, Myelinated; Neural Conduction; Nociceptors; Pain Threshold; Physical Stimulation; Plant Structures; Pressure; Pruritus; Psychophysics; Reaction Time; Sensation; Skin; Statistics, Nonparametric; Time Factors

2011
Involvement of perivascular nerves and transient receptor potential vanilloid 1 (TRPV1) in vascular responses to histamine in rat mesenteric resistance arteries.
    European journal of pharmacology, 2012, Apr-05, Volume: 680, Issue:1-3

    Topics: Acetamides; Animals; Benzoquinones; Capsaicin; Endothelium, Vascular; Heptanoic Acids; Histamine; Indomethacin; Male; Mesenteric Arteries; Methoxamine; Piperidines; Procaine; Prostaglandins; Pyridines; Rats; Rats, Wistar; Receptors, Histamine H2; Ruthenium Red; Tetrodotoxin; Thromboxane A2; TRPV Cation Channels; Vasoconstriction; Vasodilation

2012
Endothelin-1 induces itch and pain in the mouse cheek model.
    Life sciences, 2012, Oct-15, Volume: 91, Issue:13-14

    Topics: Animals; Behavior, Animal; Capsaicin; Cheek; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Histamine; Injections, Intradermal; Male; Mice; Pain; Pruritus; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Histamine H1; Receptors, Opioid, mu

2012
CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Animals; Brain; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Chloroquine; Female; Ganglia, Spinal; Green Fluorescent Proteins; Histamine; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Muscles; Mustard Plant; Pain; Plant Oils; Posterior Horn Cells; Pruritus; Sensory Receptor Cells; Skin; TRPM Cation Channels; TRPV Cation Channels

2012
Site-dependent and state-dependent inhibition of pruritogen-responsive spinal neurons by scratching.
    The European journal of neuroscience, 2012, Volume: 36, Issue:3

    Topics: Animals; Capsaicin; Chloroquine; Evoked Potentials; Histamine; Male; Mice; Mice, Inbred C57BL; Posterior Horn Cells; Pruritus; Reflex; Touch

2012
Pruriceptive spinothalamic tract neurons: physiological properties and projection targets in the primate.
    Journal of neurophysiology, 2012, Volume: 108, Issue:6

    Topics: Animals; Axons; Brain Mapping; Capsaicin; Electroencephalography; Histamine; Macaca fascicularis; Mucuna; Nociception; Plant Extracts; Posterior Horn Cells; Pruritus; Spinothalamic Tracts; Thalamic Nuclei; Touch; Touch Perception

2012
A subpopulation of nociceptors specifically linked to itch.
    Nature neuroscience, 2013, Volume: 16, Issue:2

    Topics: Action Potentials; Animals; Antirheumatic Agents; Calcium; Capsaicin; Cells, Cultured; Chloroquine; Epidermis; Ganglia, Spinal; Gene Expression Regulation; Green Fluorescent Proteins; Histamine; Hot Temperature; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Fibers; Nerve Tissue Proteins; Nociceptors; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Peptide Fragments; Plant Lectins; Proteins; Proto-Oncogene Proteins c-fos; Pruritus; Receptors, Bombesin; Receptors, G-Protein-Coupled; RNA, Untranslated; Rotarod Performance Test; Sensory Receptor Cells; Sensory System Agents; Spinal Cord; TRPV Cation Channels

2013
Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold.
    Neuron, 2013, Apr-10, Volume: 78, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cold Temperature; Diphtheria Toxin; Excitatory Postsynaptic Potentials; Female; Ganglia, Spinal; Gene Expression Regulation; Green Fluorescent Proteins; Histamine; Hot Temperature; In Vitro Techniques; Lectins; Male; Mice; Mice, Transgenic; Neurofilament Proteins; Pruritus; Pyrimidinones; Reaction Time; Receptors, Calcitonin Gene-Related Peptide; Sensory Receptor Cells; Sensory Thresholds; Skin; Sural Nerve; Time Factors; TRPM Cation Channels; TRPV Cation Channels; Ubiquitin Thiolesterase

2013
Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1.
    The journal of pain, 2013, Volume: 14, Issue:6

    Topics: Animals; Capsaicin; Chloroquine; Constriction; Disease Models, Animal; Functional Laterality; Histamine; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurofibromatosis 1; p-Methoxy-N-methylphenethylamine; Pain; Pain Measurement; Pain Threshold; Pruritus

2013
Capsaicin-sensitive cough receptors in lower airway are responsible for cough hypersensitivity in patients with upper airway cough syndrome.
    Medical science monitor : international medical journal of experimental and clinical research, 2013, Dec-03, Volume: 19

    Topics: Adult; Anesthetics, Local; Capsaicin; Case-Control Studies; Cough; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Histamine; Humans; Hypersensitivity; Hypopharynx; Lidocaine; Male; Middle Aged; Receptors, Calcitonin Gene-Related Peptide; Sputum; Statistics, Nonparametric; TRPV Cation Channels

2013
Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents.
    Journal of medicinal food, 2014, Volume: 17, Issue:6

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Dextrans; Edema; Formaldehyde; Glutamic Acid; Histamine; Inflammation; Male; Mice; Naloxone; Pain; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Rats, Wistar; Sterculia

2014
Behavioral model of itch, alloknesis, pain and allodynia in the lower hindlimb and correlative responses of lumbar dorsal horn neurons in the mouse.
    Neuroscience, 2014, Apr-25, Volume: 266

    Topics: Action Potentials; Animals; Capsaicin; Disease Models, Animal; Electrophysiology; Hindlimb; Histamine; Hyperalgesia; Injections, Intradermal; Mice; Mice, Inbred C57BL; Pain; Posterior Horn Cells; Pruritus; Sensory System Agents; Spinal Cord

2014
Three functionally distinct classes of C-fibre nociceptors in primates.
    Nature communications, 2014, Jun-20, Volume: 5

    Topics: Action Potentials; Animals; beta-Alanine; Capsaicin; Ganglia, Spinal; Histamine; Hot Temperature; Injections, Intradermal; Macaca; Male; Nerve Fibers, Unmyelinated; Nociceptors; Physical Stimulation; Statistics, Nonparametric; Stimulation, Chemical

2014
Human sensory neurons: Membrane properties and sensitization by inflammatory mediators.
    Pain, 2014, Volume: 155, Issue:9

    Topics: Action Potentials; Adenosine Triphosphate; Adolescent; Bradykinin; Capsaicin; Cell Membrane; Chloroquine; Dinoprostone; Female; Ganglia, Spinal; Histamine; Humans; Male; Patch-Clamp Techniques; Sensory Receptor Cells; Young Adult

2014
Role of spinal bombesin-responsive neurons in nonhistaminergic itch.
    Journal of neurophysiology, 2014, Nov-01, Volume: 112, Issue:9

    Topics: Animals; Bombesin; Capsaicin; Chloroquine; Histamine; Hot Temperature; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Posterior Horn Cells; Pruritus; Touch

2014
TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity.
    Molecular brain, 2014, Aug-21, Volume: 7

    Topics: Animals; Calcium; Capsaicin; Chloroquine; HEK293 Cells; Histamine; Humans; Intracellular Space; Ion Channel Gating; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Receptors, Histamine; Sensory Receptor Cells; Toll-Like Receptor 4; TRPV Cation Channels

2014
Response characteristics of pruriceptive and nociceptive trigeminoparabrachial tract neurons in the rat.
    Journal of neurophysiology, 2015, Jan-01, Volume: 113, Issue:1

    Topics: Action Potentials; Animals; beta-Alanine; Capsaicin; Cheek; Chloroquine; Histamine; Hot Temperature; Male; Mustard Plant; Neural Pathways; Nociceptive Pain; Parabrachial Nucleus; Physical Stimulation; Plant Oils; Pruritus; Rats, Sprague-Dawley; Sensory Receptor Cells; Serotonin; Touch; Trigeminal Nerve

2015
Cerebral Networks Linked to Itch-related Sensations Induced by Histamine and Capsaicin.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:6

    Topics: Adolescent; Adult; Amygdala; Brain Mapping; Capsaicin; Caudate Nucleus; Cerebral Cortex; Cross-Over Studies; Double-Blind Method; Functional Neuroimaging; Hippocampus; Histamine; Humans; Magnetic Resonance Imaging; Male; Naltrexone; Narcotic Antagonists; Paresthesia; Pruritus; Putamen; Random Allocation; Sensation; Skin Physiological Phenomena; Young Adult

2015
In vivo evaluation of the antitussive, expectorant and bronchodilating effects of extract and fractions from aerial parts of Peganum harmala linn.
    Journal of ethnopharmacology, 2015, Mar-13, Volume: 162

    Topics: Acetylcholine; Ammonia; Animals; Antitussive Agents; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Citric Acid; Cough; Expectorants; Female; Guinea Pigs; Histamine; Male; Medicine, Chinese Traditional; Mice, Inbred ICR; Peganum; Phenolsulfonphthalein; Phytotherapy; Plant Components, Aerial; Plant Extracts; Trachea

2015
Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptors.
    Molecular pain, 2015, Jan-06, Volume: 11

    Topics: Animals; beta-Alanine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Chloroquine; Disease Models, Animal; Down-Regulation; Ganglia, Spinal; Histamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Kinase C-alpha; Pruritus; Sensory Receptor Cells; TRPV Cation Channels

2015
[Role intramural ganglion airway on action of histamine].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2014, Volume: 100, Issue:9

    Topics: Anesthetics, Local; Animals; Autonomic Fibers, Preganglionic; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Male; Muscle Contraction; Muscle, Smooth; Procaine; Rats; Rats, Wistar; Sensory System Agents; Trachea

2014
Bradykinin and capsaicin induced airways obstruction in the guinea pig are platelet dependent.
    Pulmonary pharmacology & therapeutics, 2015, Volume: 33

    Topics: Airway Obstruction; Animals; Blood Platelets; Bombesin; Bradykinin; Bronchoconstriction; Busulfan; Capsaicin; Guinea Pigs; Histamine; Lung; Male; Methacholine Chloride; Platelet Aggregation; Thrombocytopenia; Trachea

2015
Anatomical evidence of pruriceptive trigeminothalamic and trigeminoparabrachial projection neurons in mice.
    The Journal of comparative neurology, 2016, Feb-01, Volume: 524, Issue:2

    Topics: Animals; Antipruritics; Brain Mapping; Capsaicin; Chloroquine; Histamine; Histamine Agonists; Male; Mice; Mice, Inbred C57BL; Neurons; Oncogene Proteins v-fos; Parabrachial Nucleus; Posterior Horn Cells; Stilbamidines; Thalamus; Trigeminal Nucleus, Spinal

2016
Osthole inhibits histamine-dependent itch via modulating TRPV1 activity.
    Scientific reports, 2016, 05-10, Volume: 6

    Topics: Animals; Antipruritics; Calcium; Calcium Channel Blockers; Capsaicin; Cells, Cultured; Coumarins; Ganglia, Spinal; Histamine; Ion Channel Gating; Male; Mice, Inbred C57BL; Neurons; Pruritus; TRPV Cation Channels

2016
Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: Mechanisms involved in the gastroprotective activity.
    Chemico-biological interactions, 2017, Jan-05, Volume: 261

    Topics: Animals; Antioxidants; Capsaicin; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Ericales; Ethanol; Female; Flavonoids; Gastrointestinal Motility; Glyburide; Histamine; Indomethacin; Male; Mice; Mucus; Naloxone; NG-Nitroarginine Methyl Ester; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Protective Agents; Stomach Ulcer; Water; Yohimbine

2017
Histaminergic and non-histaminergic elicited itch is attenuated in capsaicin-evoked areas of allodynia and hyperalgesia: A healthy volunteer study.
    European journal of pain (London, England), 2017, Volume: 21, Issue:6

    Topics: Adult; Capsaicin; Female; Healthy Volunteers; Histamine; Humans; Hyperalgesia; Male; Nociceptors; Pain Measurement; Paresthesia; Pruritus; Skin; Young Adult

2017
Sulfonamides as Selective Na
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Analgesics; Animals; Capsaicin; Cell Line; Dogs; Histamine; Mice, Inbred C57BL; Molecular Docking Simulation; NAV1.7 Voltage-Gated Sodium Channel; Pain; Protein Isoforms; Pruritus; Quinolones; Rats; Structure-Activity Relationship; Sulfonamides; Voltage-Gated Sodium Channel Blockers

2017
Specific patterns of spinal metabolites underlying α-Me-5-HT-evoked pruritus compared with histamine and capsaicin assessed by proton nuclear magnetic resonance spectroscopy.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:6

    Topics: Animals; Capsaicin; Histamine; Magnetic Resonance Spectroscopy; Male; Mice; Pruritus; Serotonin; Spinal Cord

2017
Distinct roles of NMB and GRP in itch transmission.
    Scientific reports, 2017, 11-13, Volume: 7, Issue:1

    Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Disease Models, Animal; Gastrin-Releasing Peptide; Histamine; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin B; Nociception; Nociceptors; Pruritus; Receptors, Bombesin; Signal Transduction; Skin; Spinal Cord

2017
Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:6

    Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Chloroquine; Chronic Disease; Cryotherapy; Disease Models, Animal; Histamine; Humans; Menthol; Mice; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Sensory Receptor Cells; Skin; Treatment Outcome; TRPM Cation Channels

2018
Capsaicin-sensitive cutaneous primary afferents convey electrically induced itch in humans.
    Neuroscience letters, 2018, 02-14, Volume: 666

    Topics: Administration, Cutaneous; Adult; Capsaicin; Electric Stimulation; Histamine; Humans; Male; Nociceptors; Pain Threshold; Pruritus; Skin; Young Adult

2018
HPLC profile and antiedematogenic activity of Ximenia americana L. (Olacaceae) in mice models of skin inflammation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 119

    Topics: Animals; Arachidonic Acid; Capsaicin; Chromatography, High Pressure Liquid; Croton Oil; Dermatitis; Dose-Response Relationship, Drug; Edema; Female; Histamine; Histamine Antagonists; Mice; Olacaceae; Phenol; Plant Extracts

2018
Direct Potentiation of Capsaicin Current by Histamine and Its Effect by Suplatast on Rat Trigeminal Ganglia Neurons.
    Pharmacology, 2018, Volume: 102, Issue:1-2

    Topics: Animals; Arylsulfonates; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Female; Histamine; Male; Membrane Potentials; Neurons; Rats; Sulfonium Compounds; Trigeminal Ganglion

2018
The time course of brief and prolonged topical 8% capsaicin-induced desensitization in healthy volunteers evaluated by quantitative sensory testing and vasomotor imaging.
    Experimental brain research, 2018, Volume: 236, Issue:8

    Topics: Adolescent; Adult; Capsaicin; Histamine; Histamine Agonists; Humans; Male; Nerve Fibers, Unmyelinated; Nociception; Nociceptors; Pain Threshold; Perfusion Imaging; Pruritus; Sensory System Agents; Skin; Thermosensing; Time Factors; Touch Perception; Young Adult

2018
Responses of thalamic neurons to itch- and pain-producing stimuli in rats.
    Journal of neurophysiology, 2018, 09-01, Volume: 120, Issue:3

    Topics: Action Potentials; Animals; Antipruritics; beta-Alanine; Capsaicin; Chloroquine; Histamine; Injections, Intradermal; Male; Neurons; Neurotransmitter Agents; Pain; Poisson Distribution; Pruritus; Rats; Rats, Sprague-Dawley; Serotonin; Ventral Thalamic Nuclei

2018
Effects of pruritogens and algogens on rostral ventromedial medullary ON and OFF cells.
    Journal of neurophysiology, 2018, 11-01, Volume: 120, Issue:5

    Topics: Animals; Capsaicin; Chloroquine; Evoked Potentials; Hindlimb; Histamine; Male; Medulla Oblongata; Mice; Mice, Inbred C57BL; Neurons, Afferent; Nociception; Pruritus; Reflex; Touch

2018
Sensory Qualities Point to Different Structural and Functional Skin Patterns in Chronic Pruritus Patients. A Translational Explorative Study.
    Acta dermato-venereologica, 2019, Jun-01, Volume: 99, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antipruritics; Capsaicin; Case-Control Studies; Chronic Disease; Female; Histamine; Histamine Agonists; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Peripheral Nerves; Physical Stimulation; Pruritus; Reaction Time; Skin; TRPV Cation Channels

2019
Comparison of pruritus and sensory qualities induced by capsaicin, histamine and cowhage.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2019, Volume: 33, Issue:9

    Topics: Adult; Capsaicin; Female; Healthy Volunteers; Histamine; Humans; Male; Mucuna; Pain Measurement; Pruritus; Skin Tests; Time Factors

2019
Calcium imaging of primary canine sensory neurons: Small-diameter neurons responsive to pruritogens and algogens.
    Brain and behavior, 2019, Volume: 9, Issue:12

    Topics: Animals; Cadaver; Calcium Radioisotopes; Capsaicin; Cattle; Cells, Cultured; Chloroquine; Dogs; Ganglia, Spinal; Histamine; Humans; Laminectomy; Molecular Imaging; Neurotransmitter Agents; Pain; Peptide Fragments; Pruritus; Radiopharmaceuticals; Sensory Receptor Cells; Serotonin; Serotonin Receptor Agonists; Substance P

2019
Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.
    Gut, 2021, Volume: 70, Issue:7

    Topics: Adult; Animals; Capsaicin; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enterobacteriaceae Infections; Female; Ganglia, Spinal; Histamine; Humans; Hypersensitivity; Inflammation; Irritable Bowel Syndrome; Male; Mice; Middle Aged; Neurons; Rats; Receptors, Cannabinoid; TRPV Cation Channels

2021
Flare Size but Not Intensity Reflects Histamine-Induced Itch.
    Skin pharmacology and physiology, 2020, Volume: 33, Issue:5

    Topics: Adult; Capsaicin; Female; Histamine; Humans; Male; Pain Measurement; Pruritus; Regional Blood Flow; Skin; Young Adult

2020
The TRPM3 ion channel mediates nociception but not itch evoked by endogenous pruritogenic mediators.
    Biochemical pharmacology, 2021, Volume: 183

    Topics: Animals; Capsaicin; Endothelin-1; Histamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nociception; Pruritus; TRPM Cation Channels

2021
Vaccination Granuloma Itch Treated with Capsaicin 8% Patches.
    Acta dermato-venereologica, 2020, Dec-01, Volume: 100, Issue:19

    Topics: Capsaicin; Granuloma; Histamine; Humans; Pruritus; Vaccination

2020
Early radiation-induced oral pain signaling responses are reduced with pentoxifylline treatment.
    Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association, 2021, Volume: 62, Issue:2

    Topics: Animals; Capsaicin; Histamine; Mice; Pain; Pentoxifylline; Pilot Projects; Prospective Studies; Radiation-Protective Agents; Radiotherapy; Sensory System Agents; Signal Transduction; Stomatitis; Tumor Necrosis Factor-alpha

2021
A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability.
    Scientific reports, 2021, 01-08, Volume: 11, Issue:1

    Topics: Capsaicin; Drug Discovery; Ganglia, Spinal; Histamine; Humans; Inflammation; Laurates; Sensory Receptor Cells; TRPV Cation Channels

2021
The role of pruriceptors in enhancing sensitivity to pruritogens in a murine chronic compression model of dorsal root ganglion.
    Molecular brain, 2021, 01-19, Volume: 14, Issue:1

    Topics: Animals; Calcium; Capsaicin; Cattle; Chronic Disease; Disease Models, Animal; Ganglia, Spinal; Histamine; Male; Mice, Inbred C57BL; Mice, Transgenic; Nerve Compression Syndromes; Neurons; Pain; Peptide Fragments; Pruritus; Receptors, G-Protein-Coupled; Receptors, Histamine H1; Receptors, Histamine H4; RNA, Messenger; TRPV Cation Channels; Up-Regulation

2021
Pharmacological studies on aqueous extract of Launaea arborescens from southwest Algeria.
    Journal of ethnopharmacology, 2021, Jul-15, Volume: 275

    Topics: Algeria; Analgesics; Animals; Anti-Inflammatory Agents; Asteraceae; Behavior, Animal; Capsaicin; Edema; Formaldehyde; Histamine; Hot Temperature; Inflammation; Male; Medicine, Traditional; Mice, Inbred BALB C; Pain; Pain Measurement; Plant Extracts; Serotonin; Solutions; TRPV Cation Channels

2021
TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch.
    Biomolecules, 2021, 08-06, Volume: 11, Issue:8

    Topics: Acetanilides; Animals; Calcium; Capsaicin; Female; Ganglia, Spinal; Gene Expression; Histamine; Male; Methylhistamines; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Molecular Imaging; Primary Cell Culture; Pruritus; Purines; Ruthenium Red; Sensory Receptor Cells; Signal Transduction; TRPA1 Cation Channel; TRPV Cation Channels

2021
Tachykinins amplify the action of capsaicin on central histaminergic neurons.
    Peptides, 2022, Volume: 150

    Topics: Animals; Capsaicin; Histamine; Mice; Neurons; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Tachykinins

2022
Topical Capsaicin in Poly(lactic-co-glycolic)acid (PLGA) Nanoparticles Decreases Acute Itch and Heat Pain.
    International journal of molecular sciences, 2022, May-09, Volume: 23, Issue:9

    Topics: Animals; beta-Alanine; Capsaicin; Glycols; Histamine; Hot Temperature; Humans; Mice; Nanoparticles; Pain; Pruritus

2022
Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis.
    Acta dermato-venereologica, 2023, 08-22, Volume: 103

    Topics: Animals; Calcium; Capsaicin; Chloroquine; Dermatitis, Atopic; Disease Models, Animal; Histamine; Neutrophil Infiltration; Pain; Pruritus

2023