capsaicin has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.67) | 18.7374 |
| 1990's | 12 (40.00) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Green, PG; Levine, JD | 1 |
| Kamei, J; Kasuya, Y; Tanihara, H | 1 |
| Kangrga, I; Randić, M | 1 |
| Helme, RD; Khalil, Z | 1 |
| Duckles, SP; Li, YJ | 1 |
| Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Giuliani, S; Maggi, CA; Meli, A | 1 |
| Amerini, S; Ledda, F; Mantelli, L | 2 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Hamon, M; Mauborgne, A; Pohl, M | 1 |
| Kuraishi, Y; Oyama, T; Satoh, M; Sugimoto, K; Ueda, M | 1 |
| Iwamoto, Y; Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Nagase, H; Suzuki, T | 1 |
| Butelman, ER; Ko, MC; Woods, JH | 1 |
| Herkenham, M; Hohmann, AG | 1 |
| Gyires, K; Rónai, AZ | 1 |
| Gear, RW; Levine, JD; Schmidt, BL; Tambeli, CH | 2 |
| Borgland, SL; Christie, MJ; Connor, M | 1 |
| Ji, RR; Kawasaki, Y; Kohno, T | 1 |
| Berg, KA; Clarke, WP; Hargreaves, KM; Patwardhan, AM; Sanchez, TA; Silva, YM | 1 |
| Benyhe, S; Ioja, E; Wollemann, M | 1 |
| Cai, YQ; Pan, HL; Wu, ZZ | 1 |
| Cristino, L; de Novellis, V; Di Marzo, V; Guida, F; Luongo, L; Maione, S; Marabese, I; Palazzo, E; Rossi, F; Starowicz, K | 1 |
| Fehrenbacher, JC; Hargreaves, KM; Henry, MA; Locke, EE; Sun, XX | 1 |
| Beaudry, H; Dubois, D; Gendron, L | 1 |
| Christie, MJ; Murali, SS; Napier, IA; Rycroft, BK | 1 |
| Endres-Becker, J; Fischer, O; Schäfer, M; Spahn, V; Stein, C; Zöllner, C | 1 |
| Cai, Q; Hu, WP; Liu, TT; Liu, YM; Qiu, CY; Qiu, F; Qu, ZW | 1 |
| Ashton, JC; Milne, M | 1 |
| Berg, KA; Chavera, TS; Clarke, WP; Jamshidi, RJ; Jennings, EM; LoCoco, PM; Smith, HR; Sullivan, LC | 1 |
1 trial(s) available for capsaicin and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
Capsaicin-evoked iCGRP release from human dental pulp: a model system for the study of peripheral neuropeptide secretion in normal healthy tissue.
Topics: Adolescent; Adult; Biological Assay; Biopsy; Calcitonin Gene-Related Peptide; Capsaicin; Dental Pulp; Dinoprostone; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Models, Biological; Models, Neurological; Nociceptors; Pain; Receptors, Opioid, mu; Sensory Receptor Cells; Sensory System Agents; Tetradecanoylphorbol Acetate; TRPV Cation Channels; Young Adult | 2009 |
29 other study(ies) available for capsaicin and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
Delta- and kappa-opioid agonists inhibit plasma extravasation induced by bradykinin in the knee joint of the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Bradykinin; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Inflammation; Joints; Male; Naloxone; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1992 |
Modulation of mu-mediated antitussive activity in rats by a delta agonist.
Topics: Aerosols; Animals; Antitussive Agents; Capsaicin; Cisterna Magna; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections; Male; Morphinans; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1991 |
Outflow of endogenous aspartate and glutamate from the rat spinal dorsal horn in vitro by activation of low- and high-threshold primary afferent fibers. Modulation by mu-opioids.
Topics: Afferent Pathways; Animals; Aspartic Acid; Capsaicin; Diterpenes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ganglia, Spinal; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kinetics; Naloxone; Nerve Fibers; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord; Time Factors | 1991 |
Modulation of a peripheral inflammatory response to substance P by locally administered opioid receptor agonists.
Topics: Administration, Topical; Amino Acid Sequence; Animals; Blister; Capillary Permeability; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Inflammation; Male; Molecular Sequence Data; Naloxone; Oligopeptides; Perfusion; Peripheral Nerves; Rats; Skin; Substance P; Vasodilation | 1990 |
Differential effects of neuropeptide Y and opioids on neurogenic responses of the perfused rat mesentery.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Guanethidine; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Narcotics; Neuropeptide Y; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vasoconstriction; Vasodilation | 1991 |
Characterization of opioid receptors modulating the function of capsaicin-sensitive neurons in guinea-pig atria.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic beta-Antagonists; Animals; Benzomorphans; Capsaicin; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Heart; Imidazoles; In Vitro Techniques; Male; Morphine; Neurons; Pyrrolidines; Receptors, Opioid; Reserpine | 1990 |
Opioid receptors and prejunctional modulation of capsaicin-sensitive sensory nerves in guinea-pig left atrium.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Naloxone; Neurons, Afferent; Oligopeptides; Opioid Peptides; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, mu; Reserpine | 1990 |
Opioid agonists, prostaglandin E1 and clonidine modulate non-adrenergic, non-cholinergic transmission in the mammalian heart.
Topics: Adrenergic beta-Antagonists; Alprostadil; Animals; Atrial Function; Capsaicin; Clonidine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Morphine; Myocardial Contraction; Nerve Fibers | 1990 |
Neonatal capsaicin treatment abolishes the modulations by opioids of substance P release from rat spinal cord slices.
Topics: Animals; Animals, Newborn; Capsaicin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Substance P | 1989 |
Effects of opioid drugs on capsaicin-sensitive neurones in guinea-pig atria.
Topics: Animals; Capsaicin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Narcotics; Neurons, Afferent; Sympathectomy, Chemical | 1989 |
Opioidergic inhibition of capsaicin-evoked release of glutamate from rat spinal dorsal horn slices.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzeneacetamides; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glutamate Dehydrogenase; Glutamic Acid; In Vitro Techniques; Male; Morphine; Nerve Endings; Neurons, Afferent; Opioid Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1995 |
Possible involvement of mu 2-mediated mechanisms in mu-mediated antitussive activity in the mouse.
Topics: Analgesics; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Reaction Time; Receptors, Opioid, mu | 1993 |
The role of peripheral mu opioid receptors in the modulation of capsaicin-induced thermal nociception in rhesus monkeys.
Topics: Animals; Azocines; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Hot Temperature; Macaca mulatta; Male; Naltrexone; Pain; Receptors, Opioid, mu | 1998 |
Regulation of cannabinoid and mu opioid receptors in rat lumbar spinal cord following neonatal capsaicin treatment.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Autoradiography; Capsaicin; Cyclohexanols; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Immunosuppressive Agents; Nerve Fibers; Nociceptors; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid, mu; Spinal Cord; Tritium | 1998 |
Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.
Topics: Animals; beta-Endorphin; Brain; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach Ulcer; Vagotomy | 2001 |
Nicotine withdrawal hyperalgesia and opioid-mediated analgesia depend on nicotine receptors in nucleus accumbens.
Topics: Analgesia; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hyperalgesia; Male; Mecamylamine; Morphine; Narcotics; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2001 |
Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse.
Topics: Analgesics, Opioid; Animals; Calcium Channels; Capsaicin; Cell Size; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; GTP-Binding Proteins; Lectins; Male; Mice; Mice, Inbred C57BL; Morphine; Neurons, Afferent; Nociceptin; Nociceptors; Opioid Peptides; Patch-Clamp Techniques; Trigeminal Ganglion; Vasodilator Agents; Virulence Factors, Bordetella | 2001 |
mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Narcotic Antagonists; Neurons; Nociceptors; Nucleus Accumbens; Pain; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex | 2002 |
Different effects of opioid and cannabinoid receptor agonists on C-fiber-induced extracellular signal-regulated kinase activation in dorsal horn neurons in normal and spinal nerve-ligated rats.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Lumbosacral Region; Male; Mononeuropathies; Morphine; Phosphorylation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Nerves | 2006 |
Rapid modulation of micro-opioid receptor signaling in primary sensory neurons.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Arachidonic Acid; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Gene Expression; Inositol Phosphates; Male; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptor, PAR-2; Receptors, Opioid, mu; Signal Transduction; Type C Phospholipases | 2007 |
Capsaicin inhibits the in vitro binding of peptides selective for mu- and kappa-opioid, and nociceptin-receptors.
Topics: Analgesics, Opioid; Animals; Brain; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Ligands; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Peptides; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sensory System Agents; Tritium | 2008 |
A functional link between T-type calcium channels and mu-opioid receptor expression in adult primary sensory neurons.
Topics: Analgesics, Opioid; Animals; Baclofen; Biophysics; Calcium Channel Blockers; Calcium Channels, T-Type; Capsaicin; Cells, Cultured; Drug Interactions; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; Ganglia, Spinal; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Lectins; Male; Membrane Potentials; omega-Conotoxin GVIA; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sensory Receptor Cells | 2009 |
Functional interaction between TRPV1 and mu-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia.
Topics: Action Potentials; Animals; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glutamic Acid; Hyperalgesia; Male; Medulla Oblongata; Microinjections; Naloxone; Pain Measurement; Pain Threshold; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, mu; TRPV Cation Channels | 2009 |
Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli.
Topics: Animals; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Knockout; Neurons; Neurons, Afferent; Oligopeptides; Pain; Pain Measurement; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Tachykinins | 2011 |
Opioid-related (ORL1) receptors are enriched in a subpopulation of sensory neurons and prolonged activation produces no functional loss of surface N-type calcium channels.
Topics: Analgesics, Opioid; Animals; Calcium Channels, N-Type; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Postsynaptic Potentials; Female; Ganglia, Spinal; In Vitro Techniques; Male; Nociceptin; Nociceptin Receptor; Opioid Peptides; Plant Lectins; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sensory Receptor Cells; Spinal Cord | 2012 |
Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner.
Topics: Analgesics, Opioid; Animals; Calcium; Capsaicin; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Diterpenes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Fentanyl; Ganglia, Spinal; Humans; Hyperalgesia; Male; Membrane Potentials; Morphine; Mutagenesis, Site-Directed; Protein Binding; Rats; Receptors, Opioid, mu; Sensory Receptor Cells; Substance Withdrawal Syndrome; Tritium; TRPV Cation Channels | 2013 |
Morphine inhibits acid-sensing ion channel currents in rat dorsal root ganglion neurons.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Action Potentials; Analgesics, Opioid; Animals; Capsaicin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ganglia, Spinal; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Neurons; Nociception; Pain; Protons; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; TRPV Cation Channels | 2014 |
Effect of cannabinoids on CGRP release in the isolated rat lumbar spinal cord.
Topics: Animals; Arachidonic Acids; Benzoxazines; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Agonists; Cannabinoids; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; In Vitro Techniques; Indoles; Lumbosacral Region; Male; Morpholines; Naphthalenes; Rats, Wistar; Receptors, Opioid; Sciatic Nerve; Spinal Cord; TRPV Cation Channels | 2016 |
Age-related changes in peripheral nociceptor function.
Topics: Aged; Analgesics, Opioid; Animals; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Hyperalgesia; Nociceptors; Pain; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Sensory Receptor Cells | 2022 |