capsaicin and diphenhydramine hydrochloride

capsaicin has been researched along with diphenhydramine hydrochloride in 95 studies

Research

Studies (95)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.05)	18.7374
1990's	37 (38.95)	18.2507
2000's	30 (31.58)	29.6817
2010's	25 (26.32)	24.3611
2020's	2 (2.11)	2.80

Authors

Authors	Studies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Kamei, J; Kasuya, Y; Katsuma, K	1
Hitosugi, H; Iwamoto, Y; Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M	1
Kamei, J; Kasuya, Y	1
Adcock, JJ; Buchan, P	1
Clavenna, G; Lavezzo, A; Melillo, G; Omini, C	1
Kamei, J; Kasuya, Y; Tanihara, H	1
Igarashi, H; Kamei, J; Kasuya, Y; Mori, T	1
Fuller, RW	1
Borson, DB; Bridenbaugh, R; Gorman, C; Kohrogi, H; Malfroy, B; Nadel, JA; Patton, JS	1
Bolser, DC; Chapman, RW; DeGennaro, FC; Hey, JA; O'Reilly, S	1
Bertrand, C; Daffonchio, L; Geppetti, P; Huber, O; Nadel, JA; Omini, C; Yamawaki, I	1
Kamei, J; Morita, K; Nagase, H; Saitoh, A	2
Clavenna, G; Daffonchio, L; Hernandez, A; Melillo, G; Omini, C	1
Bolser, DC; Chapman, RW; DeGennaro, FC; Egan, RW; Hey, JA; Kreutner, W; O'Reilly, S	1
Borghi, A; Ceserani, R; Dalla Rosa, C; Gallico, L; Tognella, S	1
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T	2
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H	2
Aziz, SM; Bolser, DC; Chapman, RW; DeGennaro, FC; Egan, RW; Kreutner, W; Siegel, MI	1
Igarashi, H; Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Tanihara, H	1
Iwamoto, Y; Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Nagase, H; Suzuki, T	1
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Narita, M; Suzuki, T	1
Barnes, PJ; Belvisi, MG; Chung, KF; Fox, AJ; Lalloo, UG	1
Bee, D; Crambes, O; Howard, P; Laude, EA	1
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Saitoh, A; Suzuki, T	1
Borghi, A; Cavalletti, E; Ceserani, R; Gallico, L; Tognella, S	1
Ceserani, R; Dalla Rosa, C; Gallico, L; Oggioni, N; Tognella, S	1
Bochner, F; Capon, DA; Danz, C; Kerry, N; Mikus, G; Somogyi, AA	1
Kamei, J; Morita, K	1
Dicpinigaitis, PV; Dobkin, JB	1
Arányi, P; Korbonits, D; Mikus, EG; Minker, E; Pascal, M; Révész, J; Saano, V	1
Gallico, L; Morikawa, T; Widdicombe, J	1
Fukushima, H; Isohama, Y; Kai, H; Miyata, T; Takahama, K; Wakuda, I	1
Ito, N; Kagaya, M; Kimura, K; Miura, M; Miura, S; Sano, M; Shindo, T; Shioya, T; Watanabe, A	1
Aldrich, TK; Dicpinigaitis, PV; Dobkin, JB; Rauf, K	1
Dong, F; Hasegawa, S; Iijima, H; Nomura, A; Uchida, Y; Xiang, A; Zhang, MJ	1
Jaiarj, P; Khoohaswan, P; Peungvicha, P; Ruangsomboon, O; Saraya, ML; Suriyawong, P; Wongkrajang, Y	1
Fujimura, M; Hashimoto, T; Kamio, Y; Myou, S	1
Calverley, PM; Doherty, MJ; Mister, R; Pearson, MG	1
Akahane, M; Aoyagi, S; Hiratochi, M; Ichikawa, K; Kojima, M; Shinagawa, K	1
Carey, GJ; Cuss, FM; Egan, RW; Erickson, CH; Fawzi, AB; Hey, JA; McLeod, RL; Mutter, JC; Parra, LE; Smith-Torhan, A; Tulshian, DB	1
Kastelik, JA; Morice, AH; Thompson, R	1
Ceyhan, BB; Karakurt, S	1
Ito, N; Miura, M; Sano, M; Sasaki, M; Shioya, T; Watanabe, A	1
Kamei, J; Morita, K; Onodera, K	1
Adcock, JJ; Beatch, G; Douglas, GJ; Garabette, M; Gascoigne, M; Page, CP; Walker, M	1
Ebrahimi, SA; Mahmoudian, M; Rostami, P; Zareie, MR	1
Epstein, OI; Kovaleva, VL; Zak, MS	1
Dugina, YL; Epstein, OI; Kovaleva, VL; Zak, MS	1
Fukui, S; Kagaya, M; Sano, MA; Sasaki, M; Satake, M; Shioya, T; Watanabe, A	1
Fawzi, AB; Fernandez, X; Hey, JA; Jia, Y; Kiselgof, EJ; McLeod, RL; Parra, LE; Smith-Torhan, A; Tan, Z; Tulshian, DB; Wang, X; Zhang, H	1
Barnes, PJ; Belvisi, MG; Birrell, MA; Crispino, N; Korbonits, D; Korbonits, M; Patel, HJ; Usmani, OS	1
Kotani, Y; Nakajima, T; Nakata, H; Nishimura, Y; Nishiuma, T; Yokoyama, M	1
Dicpinigaitis, PV	1
Ambrose, C; Banner, K; Battram, C; Butler, K; Giddings, J; Lewis, CA; Mok, J; Nasra, J; Poll, C; Winny, C	1
Berry, RB; Bolser, DC; Danzig, M; Davenport, PW; Hey, JA; Martin, AD; Vickroy, T	1
Hayashi, SS; Kamei, J; Nozaki, C; Takahashi, Y	1
Belvisi, MG; Birring, SS; Chung, KF; Dicpinigaitis, PV; Fontana, GA; Kastelik, JA; McGarvey, LP; Morice, AH; Smith, JA; Tatar, M; Widdicombe, J	1
Anthes, JC; Correll, CC; Jia, Y; McLeod, RL	1
Aoki, T; Endo, T; Fujii, H; Hasebe, K; Ito, T; Kamei, J; Kawai, K; Kawamura, K; Maeda, M; Nagase, H; Nakajima, M; Sakami, S; Ueno, S	1
Aoki, T; Endo, T; Fujii, H; Ito, T; Izumimoto, N; Kawai, K; Maeda, M; Matsuura, H; Nagase, H; Nakao, K; Natsume, K; Ohno, H; Saitoh, A; Sakami, S; Ueno, S	1
Dicpinigaitis, PV; Gayle, YE; Gilbert, RD; Solomon, G	1
Anthes, J; Bercovici, A; Caldwell, JP; Cheng, KC; Cui, X; Fawzi, A; Fernandez, X; Greenlee, WJ; Hey, J; Ho, GD; Korfmacher, W; Lu, SX; McLeod, RL; Ng, F; Tan, Z; Torhan, AS; Tulshian, D; Varty, GB; Xu, X; Zhang, H	1
Chen, C; Pi, HF; Raun, HL; Wang, H; Wu, JZ; Zhang, JL; Zhang, P	1
Bolser, DC; Erickson, CH; Erskine, J; Fawzi, AB; Fernandez, X; Hey, JA; Ho, GD; Jayappa, H; Lehr, C; McLeod, RL; Parra, LE; Smith-Torhan, A; Tulshian, DB; Zhang, H; Zimmer, JC	1
Andrè, E; Baraldi, PG; Gatti, R; Geppetti, P; Patacchini, R; Preti, D; Trevisani, M	1
Fujimura, M; Katayama, N; Ohkura, N; Tokuda, A	1
Birring, S; Matos, S; Monteiro, W; Parker, D; Pavord, ID; Yousaf, N	1
Bhat, R; Dicpinigaitis, PV; Negassa, A; Rhoton, WA; Tibb, AS	1
Chung, KF	1
Belvisi, MG; Birrell, MA; Dubuis, E; Grace, M; Maher, SA	1
Bende, M; Millqvist, E; Ternesten-Hasséus, E	1
Biringerova, Z; Brozmanova, M; Buday, T; Calkovsky, V; Gavliakova, S; Plevkova, J; Poliacek, I	1
Baverel, PG; Hilton, EC; Smith, JA; Van Der Graaf, PH; Woodcock, A	1
Li, PB; Luo, YL; Nie, YC; Su, WW; Wang, S; Zhang, CC; Zhang, KJ; Zheng, YF	1
Farrell, MJ; Leech, J; Mazzone, SB	1
Adcock, JJ; Belvisi, MG; Birrell, MA; Dubuis, E; Grace, MS; Maher, SA; Wortley, MA	1
Akaike, N; Hamamoto, T; Ito, Y; Kamei, S; Maeda, H; Maeda, M; Noguchi, T; Ogawa, SK; Takahama, K; Umehashi, M; Wakita, M	1
Dockry, R; Holt, K; Kelsall, A; Khalid, S; Murdoch, R; Newlands, A; Smart, K; Smith, JA; Woodcock, A	1
Johansson, EL; Millqvist, E; Ternesten-Hasséus, E	2
Cheng, X; Gao, Y; Li, S; Liu, W; Ni, J; Qi, S; Wang, C; Wang, G; Wang, J; Wang, Y; Wang, Z; Zheng, T	1
Brew, J; Caparros-Wanderley, W; Dhar, S; Dicpinigaitis, PV; Gayle, Y; Johnson, A	1
Faruqi, S; Morice, AH	1
Branà, MP; Clay, E; Page, C; Patacchini, R; Preti, D; Spina, D; Trevisani, M	1
Badri, H; Belvisi, MG; Birrell, MA; Ford, J; Holt, K; Maher, SA; McGarvey, L; Round, P; Satia, I; Smith, JA; Wortley, MA	1
Liu, L; Sun, T; Wang, L; Zhang, L	1
Brozmanova, M; Buday, T; Svajdova, S	1
Birring, SS; Cho, PSP; Fletcher, HV; Jolley, CJ; Turner, RD	1
An, Y; Cheng, L; Dai, H; Duan, Y; Li, P; Li, Y; Ma, Q; Ma, X; Wang, C; Wang, J; Wang, T; Zhang, M; Zhao, B	1
Chen, Q; Lai, K; Li, H; Liu, B; Luo, W; Peng, W; Tang, J; Yi, F; Zhan, C; Zhou, J	1

Reviews

4 review(s) available for capsaicin and diphenhydramine hydrochloride

Article	Year
Pharmacology of inhaled capsaicin in humans. Respiratory medicine, 1991, Volume: 85 Suppl A Topics: Administration, Inhalation; Airway Resistance; Antitussive Agents; Capsaicin; Cough; Humans; Neurons, Afferent; Reflex; Stimulation, Chemical	1991
Cough challenge in the assessment of cough reflex. British journal of clinical pharmacology, 2001, Volume: 52, Issue:4 Topics: Animals; Antitussive Agents; Capsaicin; Citric Acid; Clinical Trials as Topic; Cough; Humans; Nebulizers and Vaporizers; Reflex	2001
Experimentally induced cough. Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:4 Topics: Antitussive Agents; Capsaicin; Citric Acid; Cough; Humans; Patient Selection; Reflex; Reproducibility of Results; Research Design; Sensitivity and Specificity; Water	2007
TRPV1 antagonists as potential antitussive agents. Lung, 2008, Volume: 186 Suppl 1 Topics: Animals; Antitussive Agents; Capsaicin; Cough; Humans; Lung; Reflex; Sensory System Agents; Treatment Outcome; TRPV Cation Channels	2008

Trials

18 trial(s) available for capsaicin and diphenhydramine hydrochloride

Article	Year
The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans. Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:3 Topics: Adult; Aerosols; Anti-Arrhythmia Agents; Antitussive Agents; Area Under Curve; Capsaicin; Chromatography, High Pressure Liquid; Cough; Cytochrome P-450 CYP2D6; Dextromethorphan; Female; Humans; Male; Matched-Pair Analysis; Polymorphism, Genetic; Quinidine; Reference Values	1996
Antitussive effect of the GABA-agonist baclofen. Chest, 1997, Volume: 111, Issue:4 Topics: Adult; Antitussive Agents; Baclofen; Capsaicin; Cough; Double-Blind Method; Female; GABA Agonists; Humans; Male	1997
Antitussive effect of azelastine hydrochloride in patients with bronchial asthma. Arzneimittel-Forschung, 1998, Volume: 48, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Bronchial Hyperreactivity; Capsaicin; Cough; Female; Humans; Male; Middle Aged; Peak Expiratory Flow Rate; Phthalazines; Respiratory Function Tests; Vital Capacity	1998
Inhibition of capsaicin-induced cough by the gamma-aminobutyric acid agonist baclofen. Journal of clinical pharmacology, 1998, Volume: 38, Issue:4 Topics: Administration, Oral; Adult; Antitussive Agents; Baclofen; Capsaicin; Cough; Double-Blind Method; GABA Agonists; Humans	1998
Effect of oral mexiletine on the cough response to capsaicin and tartaric acid. Thorax, 2000, Volume: 55, Issue:2 Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Antitussive Agents; Bronchoconstriction; Capsaicin; Cough; Double-Blind Method; Female; Humans; Mexiletine; Placebos; Tartrates	2000
Effect of oxolamine on cough sensitivity in COPD patients. Respiratory medicine, 2002, Volume: 96, Issue:1 Topics: Aged; Antitussive Agents; Capsaicin; Cough; Cross-Over Studies; Female; Humans; Male; Middle Aged; Oxadiazoles; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Single-Blind Method	2002
Antitussive effects of the H1-receptor antagonist epinastine in patients with atopic cough (eosinophilic bronchitis). Arzneimittel-Forschung, 2004, Volume: 54, Issue:4 Topics: Adult; Aged; Antitussive Agents; Bronchial Hyperreactivity; Bronchitis; Capsaicin; Cough; Dibenzazepines; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Imidazoles; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Respiratory Function Tests	2004
Theobromine inhibits sensory nerve activation and cough. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:2 Topics: Adult; Animals; Antitussive Agents; Capsaicin; Citric Acid; Codeine; Cough; Cross-Over Studies; Disease Models, Animal; Double-Blind Method; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; Neurons, Afferent; Theobromine; Vagus Nerve	2005
The effect of codeine on the Urge-to-Cough response to inhaled capsaicin. Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:4 Topics: Antitussive Agents; Awareness; Brain Stem; Capsaicin; Codeine; Cognition; Cough; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Perception; Reflex; Respiratory Mechanics; Sensory Thresholds	2007
Inhibition of cough-reflex sensitivity by benzonatate and guaifenesin in acute viral cough. Respiratory medicine, 2009, Volume: 103, Issue:6 Topics: Administration, Inhalation; Administration, Oral; Adult; Antitussive Agents; Butylamines; Capsaicin; Common Cold; Cough; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Guaifenesin; Humans; Male; Middle Aged; Reflex; Sensory System Agents	2009
Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial. Thorax, 2010, Volume: 65, Issue:12 Topics: Aged; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Double-Blind Method; Drug Administration Schedule; Erythromycin; Female; Humans; Leukocyte Count; Male; Middle Aged; Neutrophils; Sensory System Agents; Treatment Outcome	2010
Inhalation of menthol reduces capsaicin cough sensitivity and influences inspiratory flows in chronic cough. Respiratory medicine, 2013, Volume: 107, Issue:3 Topics: Administration, Inhalation; Adult; Aged; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Inhalation; Irritants; Male; Menthol; Middle Aged; Spirometry	2013
Antitussive effects of nasal thymol challenges in healthy volunteers. Respiratory physiology & neurobiology, 2013, Jun-01, Volume: 187, Issue:1 Topics: Administration, Intranasal; Antitussive Agents; Capsaicin; Cough; Female; Healthy Volunteers; Humans; Male; Sensory System Agents; Thymol; Young Adult	2013
Pharmacodynamic modeling of cough responses to capsaicin inhalation calls into question the utility of the C5 end point. The Journal of allergy and clinical immunology, 2013, Volume: 132, Issue:4 Topics: Administration, Inhalation; Adult; Aged; Antitussive Agents; Asthma; Capsaicin; Chronic Disease; Cough; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Treatment Outcome	2013
Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial. The Journal of allergy and clinical immunology, 2014, Volume: 134, Issue:1 Topics: Administration, Inhalation; Adult; Aged; Animals; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Cross-Over Studies; Double-Blind Method; Female; Gene Expression; Humans; Male; Middle Aged; Pyrrolidines; Quality of Life; Severity of Illness Index; Treatment Outcome; TRPV Cation Channels; Urea	2014
Cough reduction using capsaicin. Respiratory medicine, 2015, Volume: 109, Issue:1 Topics: Administration, Oral; Adult; Aged; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Cross-Over Studies; Double-Blind Method; Female; Humans; Irritants; Male; Middle Aged; Sensory Thresholds; Severity of Illness Index; Young Adult	2015
Inhibition of cough reflex sensitivity by diphenhydramine during acute viral respiratory tract infection. International journal of clinical pharmacy, 2015, Volume: 37, Issue:3 Topics: Adult; Antitussive Agents; Capsaicin; Cough; Dextromethorphan; Diphenhydramine; Double-Blind Method; Female; Humans; Male; Reflex; Respiratory Tract Infections; Young Adult	2015
Effects of treatment with montelukast alone, budesonide/formoterol alone and a combination of both in cough variant asthma. Respiratory research, 2022, Oct-10, Volume: 23, Issue:1 Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Antitussive Agents; Asthma; Budesonide; Budesonide, Formoterol Fumarate Drug Combination; Capsaicin; Cough; Cyclopropanes; Formoterol Fumarate; Humans; Inflammation; Leukotriene Antagonists; Quinolines; Sulfides	2022

Other Studies

73 other study(ies) available for capsaicin and diphenhydramine hydrochloride

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Involvement of mu-opioid receptors in the antitussive effects of pentazocine. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antitussive Agents; Benzomorphans; Capsaicin; Cough; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Naloxone; Pentazocine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu	1992
Involvement of haloperidol-sensitive sigma-sites in antitussive effects. European journal of pharmacology, 1992, Nov-24, Volume: 224, Issue:1 Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Drug Interactions; Guanidines; Haloperidol; Injections, Intraperitoneal; Male; Phenazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stereoisomerism	1992
Antitussive effects of Ca2+ channel antagonists. European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1 Topics: Animals; Antitussive Agents; Calcium Channel Blockers; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Drug Synergism; Flunarizine; Guinea Pigs; Male; Morphine; Nifedipine; Verapamil	1992
Capsaicin-induced bronchoconstriction in the guinea-pig: contribution of vagal cholinergic reflexes, local axon reflexes and their modulation by BW443C81. British journal of pharmacology, 1992, Volume: 105, Issue:2 Topics: Amino Acid Sequence; Animals; Antitussive Agents; Atropine; Axons; Bronchoconstriction; Capsaicin; Codeine; Guinea Pigs; In Vitro Techniques; Male; Molecular Sequence Data; Oligopeptides; Parasympathetic Nervous System; Reflex; Vagotomy; Vagus Nerve	1992
Peripheral site of action of levodropropizine in experimentally-induced cough: role of sensory neuropeptides. Pulmonary pharmacology, 1992, Volume: 5, Issue:2 Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Electric Stimulation; Guinea Pigs; Injections, Intraventricular; Male; Neuropeptides; Propylene Glycols; Vagus Nerve	1992
Modulation of mu-mediated antitussive activity in rats by a delta agonist. European journal of pharmacology, 1991, Oct-02, Volume: 203, Issue:1 Topics: Aerosols; Animals; Antitussive Agents; Capsaicin; Cisterna Magna; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections; Male; Morphinans; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1991
Effects of 8-hydroxy-2-(di-n-propylamino)tetralin, a selective agonist of 5-HT1A receptors, on the cough reflex in rats. European journal of pharmacology, 1991, Oct-15, Volume: 203, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Tetrahydronaphthalenes	1991
Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs. The Journal of clinical investigation, 1989, Volume: 84, Issue:3 Topics: Aerosols; Animals; Antitussive Agents; Capsaicin; Cough; Guinea Pigs; Humans; Liposomes; Male; Neprilysin; Recombinant Proteins; Sodium Chloride; Substance P; Tachykinins	1989
Pharmacological studies of allergic cough in the guinea pig. European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3 Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsaicin; Chlorpheniramine; Cimetidine; Codeine; Cough; Drug Hypersensitivity; Guinea Pigs; Hexamethonium; Histamine Antagonists; Indomethacin; Injections, Subcutaneous; Ipratropium; Loratadine; Male; Ovalbumin; Piperidines; Receptors, Histamine H1; Receptors, Histamine H2	1995
Levodropropizine reduces capsaicin- and substance P-induced plasma extravasation in the rat trachea. European journal of pharmacology, 1993, Oct-12, Volume: 243, Issue:1 Topics: Animals; Antitussive Agents; Blood Pressure; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Heart Rate; In Vitro Techniques; Muscle Contraction; Peripheral Nervous System; Platelet Activating Factor; Propylene Glycols; Rats; Rats, Inbred F344; Substance P; Trachea; Urinary Bladder	1993
Antagonistic effect of buprenorphine on the antitussive effect of morphine is mediated via the activation of mu 1-opioid receptors. Life sciences, 1995, Volume: 57, Issue:16 Topics: Animals; Antitussive Agents; Buprenorphine; Capsaicin; Cough; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Opioid, mu; Time Factors	1995
Effectiveness of levodropropizine against cigarette smoke-induced airway hyperreactivity: possible mechanism. European journal of pharmacology, 1993, Apr-01, Volume: 228, Issue:5-6 Topics: Airway Resistance; Animals; Antitussive Agents; Bronchoconstriction; Capsaicin; Codeine; Guinea Pigs; Male; Propylene Glycols; Substance P; Tobacco Smoke Pollution	1993
Peripheral and central sites of action of GABA-B agonists to inhibit the cough reflex in the cat and guinea pig. British journal of pharmacology, 1994, Volume: 113, Issue:4 Topics: Animals; Antitussive Agents; Baclofen; Capsaicin; Cats; Central Nervous System; Codeine; Cough; GABA Agonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Guinea Pigs; In Vitro Techniques; Injections, Intraventricular; Male; Oligopeptides; Organophosphorus Compounds; Peripheral Nervous System	1994
Moguisteine: a novel peripheral non-narcotic antitussive drug. British journal of pharmacology, 1994, Volume: 112, Issue:3 Topics: Aerosols; Animals; Antitussive Agents; Binding, Competitive; Capsaicin; Citrates; Citric Acid; Codeine; Cough; Dogs; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Injections, Intraventricular; Male; Naloxone; Physical Stimulation; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Thiazoles; Thiazolidines	1994
Involvement of delta 1-opioid receptor antagonism in the antitussive effect of delta-opioid receptor antagonists. European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3 Topics: Animals; Antitussive Agents; Benzylidene Compounds; Capsaicin; Cough; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta	1994
Antitussive effect of [Met5]enkephalin-Arg6-Phe7 in mice. European journal of pharmacology, 1994, Mar-03, Volume: 253, Issue:3 Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu	1994
Antitussive effects of GABAB agonists in the cat and guinea-pig. British journal of pharmacology, 1993, Volume: 110, Issue:1 Topics: Animals; Antitussive Agents; Baclofen; Capsaicin; Cats; Codeine; Cough; Dextromethorphan; Electromyography; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Irritants; Male; Organophosphorus Compounds; Respiratory Muscles	1993
Antitussive effect of captopril, an angiotensin converting enzyme inhibitor, in the rat. Research communications in chemical pathology and pharmacology, 1993, Volume: 81, Issue:3 Topics: Animals; Antitussive Agents; Capsaicin; Captopril; Cough; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Sprague-Dawley	1993
Antitussive effects of naltrindole, a selective delta-opioid receptor antagonist, in mice and rats. European journal of pharmacology, 1993, Nov-09, Volume: 249, Issue:2 Topics: Animals; Antitussive Agents; Capsaicin; Cough; Drug Interactions; Endorphins; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa	1993
Antitussive effect of beta-endorphin is mediated by mu-opioid receptors, but not by kappa- or epsilon-opioid receptors. European journal of pharmacology, 1993, Mar-23, Volume: 233, Issue:2-3 Topics: Animals; Antitussive Agents; beta-Endorphin; Capsaicin; Cough; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma	1993
Possible involvement of mu 2-mediated mechanisms in mu-mediated antitussive activity in the mouse. Neuroscience letters, 1993, Jan-12, Volume: 149, Issue:2 Topics: Analgesics; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Reaction Time; Receptors, Opioid, mu	1993
The antitussive effect of cromakalim in rats is not associated with adenosine triphosphate sensitive K+ channels. Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:2 Topics: Adenosine Triphosphate; Animals; Antitussive Agents; Benzopyrans; Calcium Channels; Capsaicin; Cough; Cromakalim; Dose-Response Relationship, Drug; Glyburide; Injections, Intraperitoneal; Male; Methysergide; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Reflex; Tetraethylammonium Compounds	1993
Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 79, Issue:4 Topics: Animals; Antitussive Agents; Bronchodilator Agents; Capsaicin; Citrates; Citric Acid; Cough; Guinea Pigs; Irritants; Male; Protons; Saline Solution, Hypertonic; Terbutaline	1995
Antitussive and antibronchoconstriction actions of fenspiride in guinea-pigs. The European respiratory journal, 1995, Volume: 8, Issue:10 Topics: Acetates; Acetic Acid; Aerosols; Airway Resistance; Animals; Antitussive Agents; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neurokinin A; Spiro Compounds; Substance P	1995
Buprenorphine exerts its antinociceptive activity via mu 1-opioid receptors. Life sciences, 1995, Mar-03, Volume: 56, Issue:15 Topics: Analgesics, Opioid; Animals; Antitussive Agents; Buprenorphine; Capsaicin; Cough; Male; Mice; Mice, Inbred ICR; Receptors, Opioid	1995
Antitussive activity of moguisteine enantiomers in guinea-pigs and rats. The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1 Topics: Administration, Oral; Aerosols; Animals; Antacids; Antitussive Agents; Capsaicin; Citric Acid; Cough; Dose-Response Relationship, Drug; Female; Guinea Pigs; Injections, Intraperitoneal; Lethal Dose 50; Male; Rats; Rats, Sprague-Dawley; Species Specificity; Stereoisomerism; Thiazoles; Thiazolidines	1996
Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo. The European respiratory journal, 1996, Volume: 9, Issue:3 Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Antitussive Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Inflammation; Male; Regression Analysis; Respiratory System; Smoke; Thiazoles; Thiazolidines	1996
Antitussive effect of moguisteine on the enhanced coughing associated with enalapril in guinea-pig. European journal of pharmacology, 1996, Sep-26, Volume: 312, Issue:2 Topics: Animals; Antitussive Agents; Capsaicin; Cough; Enalapril; Guinea Pigs; Male; Thiazoles; Thiazolidines	1996
Experimental studies on the antitussive properties of the new xanthine derivative 1H-purine-2,6-dione, 3,7-dihydro-3-methyl-7[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]. 1st communication: in vivo demonstration of the effects on animal models of cough and of Arzneimittel-Forschung, 1997, Volume: 47, Issue:4 Topics: Animals; Antitussive Agents; Capsaicin; Citric Acid; Cough; Female; Guinea Pigs; In Vitro Techniques; Male; Mucociliary Clearance; Oxadiazoles; Physical Stimulation; Purines; Rabbits	1997
Actions of moguisteine on cough and pulmonary rapidly adapting receptor activity in the guinea pig. Pharmacological research, 1997, Volume: 35, Issue:2 Topics: Aerosols; Animals; Antitussive Agents; Binding Sites; Capsaicin; Cough; Dimethyl Sulfoxide; Female; Guinea Pigs; Lung; Male; Mechanoreceptors; Receptors, Cell Surface; Thiazoles; Thiazolidines	1997
Differential effect of codeine on coughs caused by mechanical stimulation of two different sites in the airway of guinea pigs. European journal of pharmacology, 1997, Jun-18, Volume: 329, Issue:1 Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Male; Physical Stimulation; Trachea	1997
Effects of airway inflammation on cough response in the guinea pig. Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:5 Topics: Animals; Antitussive Agents; Benzamides; Bronchoalveolar Lavage Fluid; Capsaicin; Codeine; Cough; Dipeptides; Female; Guinea Pigs; Indoles; Inflammation; Peptides, Cyclic; Piperidines; Quinuclidines; Receptors, Neurokinin-2; Receptors, Tachykinin; Respiratory Hypersensitivity; Respiratory Tract Diseases	1998
Anticough and antimicrobial activities of Psidium guajava Linn. leaf extract. Journal of ethnopharmacology, 1999, Nov-01, Volume: 67, Issue:2 Topics: Animals; Anti-Bacterial Agents; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Microbial Sensitivity Tests; Muscle Contraction; Muscle, Smooth; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Staphylococcus aureus; Trachea	1999
Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease. Thorax, 2000, Volume: 55, Issue:8 Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Antitussive Agents; Asthma; Capsaicin; Cough; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Middle Aged	2000
Participation of thromboxane A(2) in the cough response in guinea-pigs: antitussive effect of ozagrel. British journal of pharmacology, 2000, Volume: 131, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antitussive Agents; Capsaicin; Cough; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Male; Methacrylates; Thromboxane A2; Thromboxane-A Synthase	2000
Nociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptors. British journal of pharmacology, 2001, Volume: 132, Issue:6 Topics: Animals; Antitussive Agents; Capsaicin; CHO Cells; Cough; Cricetinae; Disease Models, Animal; Guinea Pigs; Male; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid	2001
Mechanism of the antitussive effect of azelastine in guinea pigs. Arzneimittel-Forschung, 2002, Volume: 52, Issue:6 Topics: Animals; Antitussive Agents; Bronchoalveolar Lavage Fluid; Capsaicin; Cough; Female; Guinea Pigs; Phthalazines; Substance P; Trachea	2002
Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs. Japanese journal of pharmacology, 2002, Volume: 89, Issue:2 Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Drug Antagonism; Glyburide; Guinea Pigs; Male; Naloxone; Pinacidil; Potassium Channels; Thiazoles; Thiazolidines	2002
RSD931, a novel anti-tussive agent acting on airway sensory nerves. British journal of pharmacology, 2003, Volume: 138, Issue:3 Topics: Administration, Inhalation; Aerosols; Animals; Antitussive Agents; Bronchi; Bronchoconstriction; Capsaicin; Carnosine; Citric Acid; Cough; Dose-Response Relationship, Drug; Female; Guinea Pigs; Lidocaine; Lung; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Rabbits; Time Factors	2003
The antitussive effects of endomorphin-1 and endomorphin-2 in mice. European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3 Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid, kappa; Receptors, Opioid, mu	2003
Interaction of noscapine with the bradykinin mediation of the cough response. Acta physiologica Hungarica, 2003, Volume: 90, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antitussive Agents; Bradykinin; Capsaicin; Captopril; Cough; Dose-Response Relationship, Drug; Drug Interactions; Enalapril; Guinea Pigs; Male; Naloxone; Narcotic Antagonists; Noscapine; Quinolines; Receptor, Bradykinin B2	2003
Antitussive activity of Anar. Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7 Topics: Animals; Antibodies; Antitussive Agents; Capsaicin; Citric Acid; Cough; Female; Guinea Pigs; Lung; Male; Morphine	2003
Ultralow doses of antibodies to inflammatory mediators: antitussive properties of antibodies to bradykinin, histamine, and serotonin. Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7 Topics: Animals; Antibodies; Antitussive Agents; Bradykinin; Capsaicin; Citric Acid; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Humans; Male; Serotonin	2003
Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig. Pharmacology, 2004, Volume: 71, Issue:3 Topics: Aerosols; Animals; Antitussive Agents; Calcium; Capsaicin; CHO Cells; Cough; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Imidazoles; In Vitro Techniques; Injections, Intraperitoneal; Male; Nociceptin Receptor; Nodose Ganglion; Receptors, Opioid; Spiro Compounds	2004
Cough sensitivity in pure cough variant asthma elicited using continuous capsaicin inhalation. Allergology international : official journal of the Japanese Society of Allergology, 2006, Volume: 55, Issue:2 Topics: Administration, Inhalation; Adult; Antitussive Agents; Asthma; Capsaicin; Cough; Female; Humans; Male; Middle Aged; Time Factors	2006
Animal models of cough: literature review and presentation of a novel cigarette smoke-enhanced cough model in the guinea-pig. Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:4 Topics: Animals; Antitussive Agents; Area Under Curve; Atropine; Capsaicin; Citric Acid; Codeine; Cough; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Inhalation Exposure; Male; Plethysmography, Whole Body; Reflex; Smoke; Terbutaline	2007
Role of cyclin-dependent kinase 5 in capsaicin-induced cough. European journal of pharmacology, 2007, Jul-02, Volume: 566, Issue:1-3 Topics: Animals; Antitussive Agents; Capsaicin; Citric Acid; Cough; Cyclin-Dependent Kinase 5; Male; Mice; Mice, Inbred ICR; Protein Kinase Inhibitors; Purines; Roscovitine	2007
ERS guidelines on the assessment of cough. The European respiratory journal, 2007, Volume: 29, Issue:6 Topics: Aerosols; Animals; Antitussive Agents; Capsaicin; Citric Acid; Clinical Trials as Topic; Cough; Disease Models, Animal; Humans; Lung Diseases; Practice Guidelines as Topic; Quality of Life; Tachyphylaxis; Treatment Outcome; Water	2007
Structure-antitussive activity relationships of naltrindole derivatives. Identification of novel and potent antitussive agents. Journal of medicinal chemistry, 2008, Aug-14, Volume: 51, Issue:15 Topics: Alkylation; Animals; Antitussive Agents; Capsaicin; CHO Cells; Cough; Cricetinae; Cricetulus; Male; Mice; Molecular Structure; Naltrexone; Rats; Structure-Activity Relationship	2008
Design and synthesis of a metabolically stable and potent antitussive agent, a novel delta opioid receptor antagonist, TRK-851. Bioorganic & medicinal chemistry, 2008, Sep-01, Volume: 16, Issue:17 Topics: Administration, Oral; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred Strains; Molecular Conformation; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Stereoisomerism; Structure-Activity Relationship	2008
The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety. Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9 Topics: Animals; Anti-Anxiety Agents; Antitussive Agents; Anxiety; Capsaicin; Chemistry, Pharmaceutical; Cough; Drug Design; Guinea Pigs; Humans; Ligands; Nociceptin Receptor; Pregnane X Receptor; Receptors, Opioid; Receptors, Steroid; Structure-Activity Relationship; Tropanes	2009
Addictive evaluation of cholic acid-verticinone ester, a potential cough therapeutic agent with agonist action of opioid receptor. Acta pharmacologica Sinica, 2009, Volume: 30, Issue:5 Topics: Animals; Antitussive Agents; Capsaicin; Cevanes; Cholic Acids; Cough; Disease Models, Animal; Drug Interactions; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Naloxone; Opioid-Related Disorders; Receptors, Opioid; Substance Withdrawal Syndrome	2009
Effect of a novel NOP receptor agonist (SCH 225288) on guinea pig irritant-evoked, feline mechanically induced and canine infectious tracheobronchitis cough. Pharmacology, 2009, Volume: 84, Issue:3 Topics: Animals; Antitussive Agents; Bordetella bronchiseptica; Bordetella Infections; Capsaicin; Cats; CHO Cells; Cough; Cricetinae; Cricetulus; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Male; Nociceptin Receptor; Receptors, Opioid; Species Specificity; Time Factors; Tropanes	2009
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents. British journal of pharmacology, 2009, Volume: 158, Issue:6 Topics: Acrolein; Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Drug Delivery Systems; Guinea Pigs; Isothiocyanates; Male; Oxidative Stress; Smoke; Transient Receptor Potential Channels	2009
Do beta(2)-agonists inhibit capsaicin-induced cough? The European respiratory journal, 2010, Volume: 36, Issue:2 Topics: Adrenergic beta-Agonists; Animals; Antitussive Agents; Bronchodilator Agents; Capsaicin; Cough; Guinea Pigs; Humans; Receptors, Adrenergic, beta-2; Terbutaline; Time Factors	2010
Effect of viral upper respiratory tract infection on the urge-to-cough sensation. Respiratory medicine, 2011, Volume: 105, Issue:4 Topics: Adult; Antitussive Agents; Capsaicin; Common Cold; Cough; Female; Humans; Male; Reflex; Sensation; Sensory System Agents	2011
Chronic 'cough hypersensitivity syndrome': a more precise label for chronic cough. Pulmonary pharmacology & therapeutics, 2011, Volume: 24, Issue:3 Topics: Animals; Antitussive Agents; Capsaicin; Chronic Disease; Citric Acid; Cough; Humans; Quality of Life; Respiratory Hypersensitivity; Syndrome	2011
Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin. Thorax, 2012, Volume: 67, Issue:10 Topics: Acrolein; Adult; Aged; Animals; Antitussive Agents; Bradykinin; Calcium; Capsaicin; Cough; Dinoprostone; Female; Guinea Pigs; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Statistics, Nonparametric; Transient Receptor Potential Channels; Vagus Nerve	2012
Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:12 Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Female; Flavanones; Guinea Pigs; Lung; Male; Neprilysin; Neurogenic Inflammation; Nicotiana; Propylene Glycols; Receptors, Neurokinin-1; Smoke; Substance P; Thiazolidines	2013
Brain activity associated with placebo suppression of the urge-to-cough in humans. American journal of respiratory and critical care medicine, 2013, Nov-01, Volume: 188, Issue:9 Topics: Adolescent; Adult; Antitussive Agents; Brain; Brain Mapping; Capsaicin; Cough; Female; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Male; Placebo Effect; Placebos; Sensory System Agents; Young Adult	2013
Theophylline inhibits the cough reflex through a novel mechanism of action. The Journal of allergy and clinical immunology, 2014, Volume: 133, Issue:6 Topics: Action Potentials; Animals; Antitussive Agents; Calcium; Capsaicin; Cough; Disease Models, Animal; Ganglia, Sensory; Guinea Pigs; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Male; Nerve Fibers, Unmyelinated; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Reflex; Sensory Receptor Cells; Small-Conductance Calcium-Activated Potassium Channels; Theophylline; Vagus Nerve	2014
Potent cough suppression by physiologically active substance in human plasma. General physiology and biophysics, 2014, Volume: 33, Issue:2 Topics: Animals; Antitussive Agents; Biological Assay; Blood Chemical Analysis; Capsaicin; Chromatography, Affinity; Codeine; Cough; Drug Discovery; Factor XIa; Guinea Pigs; Heparin; Male; Mechanical Phenomena	2014
In vivo evaluation of the antitussive, expectorant and bronchodilating effects of extract and fractions from aerial parts of Peganum harmala linn. Journal of ethnopharmacology, 2015, Mar-13, Volume: 162 Topics: Acetylcholine; Ammonia; Animals; Antitussive Agents; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Citric Acid; Cough; Expectorants; Female; Guinea Pigs; Histamine; Male; Medicine, Chinese Traditional; Mice, Inbred ICR; Peganum; Phenolsulfonphthalein; Phytotherapy; Plant Components, Aerial; Plant Extracts; Trachea	2015
Reply to correspondence regarding the paper "Ternesten-Hasséus E, Johansson EL, Millqvist E. Cough reduction using capsaicin. Respir Med. 2015 Jan;109(1):27-37.". Respiratory medicine, 2015, Volume: 109, Issue:7 Topics: Antitussive Agents; Capsaicin; Cough; Female; Humans; Male	2015
Cough reduction using capsaicin: An alternative mechanistic hypothesis. Respiratory medicine, 2015, Volume: 109, Issue:7 Topics: Antitussive Agents; Capsaicin; Cough; Female; Humans; Male	2015
Ozone-Induced Hypertussive Responses in Rabbits and Guinea Pigs. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:1 Topics: Aminopyridines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Benzamides; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Citric Acid; Cough; Cyclopropanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Guinea Pigs; Male; Neutrophil Infiltration; Oxidants, Photochemical; Ozone; Propylene Glycols; Rabbits; Transient Receptor Potential Channels	2016
XEN-D0501, a Novel Transient Receptor Potential Vanilloid 1 Antagonist, Does Not Reduce Cough in Patients with Refractory Cough. American journal of respiratory and critical care medicine, 2017, 11-15, Volume: 196, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; TRPV Cation Channels	2017
The research of the possible mechanism and the treatment for capsaicin-induced cough. Pulmonary pharmacology & therapeutics, 2018, Volume: 49 Topics: Animals; Antitussive Agents; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Codeine; Cough; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Guinea Pigs; Male; Neurokinin A; Pyrrolidines; Substance P; TRPV Cation Channels; Urea	2018
Lidocaine, a Non-selective Inhibitor of Voltage-Gated Sodium Channels, Blocks Chemically-Induced Cough in Awake Naïve Guinea Pigs. Advances in experimental medicine and biology, 2019, Volume: 1160 Topics: Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Cough; Guinea Pigs; Lidocaine; Voltage-Gated Sodium Channels; Wakefulness	2019
Impaired cough suppression in chronic refractory cough. The European respiratory journal, 2019, Volume: 53, Issue:5 Topics: Administration, Inhalation; Adult; Antitussive Agents; Capsaicin; Case-Control Studies; Chronic Disease; Cough; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Treatment Outcome	2019
Therapeutic effects and mechanisms study of Hanchuan Zupa Granule in a Guinea pig model of cough variant asthma. Journal of ethnopharmacology, 2021, Apr-06, Volume: 269 Topics: Animals; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Body Weight; Capsaicin; Cough; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; GATA3 Transcription Factor; Glycyrrhizic Acid; Guinea Pigs; Lung; Medicine, Chinese Traditional; Ovalbumin; Respiratory Hypersensitivity; T-Box Domain Proteins; Th1 Cells; Th2 Cells; Toll-Like Receptor 4; Triterpenes	2021