capsaicin has been researched along with dinoprostone in 143 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (6.29) | 18.7374 |
| 1990's | 47 (32.87) | 18.2507 |
| 2000's | 50 (34.97) | 29.6817 |
| 2010's | 34 (23.78) | 24.3611 |
| 2020's | 3 (2.10) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Cao, Z; Hammock, BD; Hwang, SH; Lee, KS; Li, X; Morisseau, C; Wagner, K; Xu, J; Yang, J | 1 |
| Håkanson, R; Wallengren, J | 1 |
| Esplugues, JV; Moncada, S; Whittle, BJ | 1 |
| Barnes, PJ; Fuller, RW; Stone, R | 1 |
| Fändriks, L; Hamlet, A; Jönson, C | 1 |
| Bauer, MB; Gebhart, GF; Meller, ST | 1 |
| Cagnoni, M; Jantsch, S; Marabini, S; Matucci-Cerinic, M; Partsch, G | 1 |
| Levine, JD; Pitchford, S | 1 |
| Del Bianco, E; Fanciullacci, M; Folco, GC; Geppetti, P; Maggi, CA; Manzini, S; Tramontana, M; Vigano, T | 1 |
| Guth, PH; Holzer, P; Lippe, IT; Livingston, EH; Pabst, MA; Peskar, BA; Peskar, BM | 1 |
| Barnes, PJ; Chung, KF; McCusker, MT; Roberts, NM | 1 |
| Choudry, NB; Fuller, RW; Pride, NB | 1 |
| Basbaum, AI; Goetzl, EJ; Kwiat, GC; Levine, JD; Martin, HA | 1 |
| Conte, B; Furio, M; Giuliani, S; Gragnani, L; Maggi, CA; Meli, A; Meli, P; Santicioli, P | 1 |
| Boctor, AM; Flynn, DL; Rafferty, MF | 1 |
| Holzer, P; Sametz, W | 1 |
| Baccaglini, PI; Hogan, PG | 1 |
| Bynke, G; Håkanson, R; Hörig, J | 1 |
| Andoh, R; Kisara, K; Sakurada, S; Sato, T; Takahashi, N | 1 |
| Amann, R; Donnerer, J; Holzer, P; Schuligoi, R | 1 |
| Grønbech, JE; Lacy, ER | 1 |
| Kinoshita, M; Kume, E; Tamaki, H | 1 |
| Bielanski, W; Brzozowski, T; Konturek, SJ; Schally, AV | 1 |
| Hamberger, A; Hedner, T; Malmberg, AB | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Kaneko, H; Kato, K; Király, A; Sütö, G; Taché, Y; Yoneda, M | 1 |
| Dempsey, DT; Grabowski, MW; Merchant, NB; Ritchie, WP; Rizzo, M | 1 |
| Amann, R; Donnerer, J; Schuligoi, R | 1 |
| Adcock, JJ; Higenbottam, TW; Mohammed, SP | 1 |
| Birrell, GJ; McQueen, DS | 1 |
| Gold, MS; Levine, JD; Reichling, DB; Shuster, MJ | 1 |
| Lee, LY; Morton, RF | 1 |
| Chang, WC; Chen, IJ; Tang, CS; Yang, JM; Yang, YC; Yu, KL | 1 |
| Dastmalchi, S; Gold, MS; Levine, JD | 1 |
| Khasar, SG; Levine, JD | 1 |
| Noda, K; Suzuki, K; Ueda, Y; Yoda, K | 1 |
| Calcutt, NA; Hua, XY; Malmberg, AB | 1 |
| Cardenas, CG; Cooper, BY; Del Mar, LP; Scroggs, RS | 1 |
| Basbaum, AI; Brandon, EP; Idzerda, RL; Liu, H; Malmberg, AB; McKnight, GS | 1 |
| Blenk, KH; Jänig, W; Michaelis, M; Vogel, C | 1 |
| Joe, B; Lokesh, BR | 1 |
| Lopshire, JC; Nicol, GD | 2 |
| Knotková-Urbancová, H; Kress, M; Reeh, PW; Vitásková, Z; Vlachová, V; Vyklický, L | 1 |
| Gruetter, CA; Lemke, S; Spurlock, B; Szarek, JL | 1 |
| Fallone, CA; MacNaughton, WK; Morris, GP; Pringle, GC | 1 |
| Brzozowska, I; Brzozowski, T; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecién, S; Pajdo, R | 1 |
| Grundy, D; Maubach, KA | 1 |
| Hamilton, SG; McMahon, SB; Wade, A | 1 |
| Ebersberger, A; Messlinger, K; Oppmann, M; Pawlak, M; Schepelmann, K | 1 |
| Dirig, DM; Yaksh, TL | 1 |
| Hori, Y; Ito, S; Minami, T; Mishina, M; Okuda-Ashitaka, E; Sakimura, K; Sakuma, S; Sugimoto, T | 1 |
| Green, MR; Reilly, DM | 1 |
| Averbeck, B; Bove, GM; Reeh, PW; Sauer, SK | 1 |
| Alves, RV; Calixto, JB; Chakravarty, S; de Campos, RO; Ferreira, J; Kyle, DJ; Mavunkel, BJ | 1 |
| Gebhart, GF; Su, X; Wachtel, RE | 1 |
| Kohút, A; Mirossay, L; Mojzis, J | 1 |
| Distler, C; Habelt, C; Kessler, F; Kress, M; Reeh, PW | 1 |
| Cho, H; Cho, S; Hwang, SW; Jung, J; Kang, CJ; Kim, D; Kwak, J; Lee, SY; Min, KH; Oh, U; Suh, YG | 1 |
| Southall, MD; Vasko, MR | 1 |
| Averbeck, B; Izydorczyk, I; Kress, M | 1 |
| Gu, Q; Ho, CY; Hong, JL; Lee, LY | 1 |
| Akiba, Y; Engel, E; Furukawa, O; Guth, PH; Kaunitz, JD; Nastaskin, I | 1 |
| Brandt, MR; Furness, MS; Mello, NK; Negus, SS; Rice, KC | 1 |
| Ito, S; Matsumura, S; Minami, T; Mishina, M; Mori, H; Okuda-Ashitaka, E; Sakimura, K; Shimamoto, K | 1 |
| Fabiani, ME; Story, DF; Vlahos, R | 1 |
| Bakoshi, S; Ito, S; Minami, T; Mine, O; Mori, H; Muratani, T; Nakano, H | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Ptak, A; Sliwowski, Z | 1 |
| Dussor, GO; Flores, CM; Harding-Rose, C; Hargreaves, KM; Kilo, S; Leong, AS | 1 |
| Kasai, M; Mizumura, K | 1 |
| Brzozowska, I; Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Ptak, A | 1 |
| Gereau, RW; Yang, D | 1 |
| Bhave, G; Gereau, RW; Hu, HJ | 1 |
| Gharibova, LS; Li, T; Nicol, GD; Pei, Y; Southall, MD; Travers, JB | 1 |
| Barna, I; Gyires, K | 1 |
| Choe, SY; Han, IS; Kawada, T; Kim, BS; Kim, CS; Kurata, T; Yu, R | 1 |
| Ates, M; Gühring, H; Hamza, M; Seidel, K | 1 |
| Handwerker, HO; Hilliges, M; Schmelz, M; Schmidt, R; Torebjork, HE; Weidner, C | 1 |
| Gu, Q; Kwong, K; Lee, LY | 1 |
| Chen, CW; Fu, WM; Ho, FM; Lee, ST; Lin, WW; Wu, WT | 1 |
| Akopian, AN; Flores, CM; Hargreaves, KM; Patwardhan, A; Price, TJ | 1 |
| Hayashi, Y; Murakami, M; Takeeda, M; Takeuchi, K; Yamato, M | 1 |
| Aihara, E; Aoi, M; Nakashima, M; Takeuchi, K | 1 |
| Jenkins, DW; Langmead, CJ; Parsons, AA; Strijbos, PJ | 1 |
| Brzozowski, T; Drozdowicz, D; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Pawlik, WW; Sliwowski, Z | 1 |
| Kwong, K; Lee, LY | 1 |
| Aihara, E; Hayashi, M; Kobata, A; Sasaki, Y; Takeuchi, K | 1 |
| Ando, R; Watanabe, C | 1 |
| Nagy, I; Sántha, P; Singh Tahim, A | 1 |
| Bergren, DR | 1 |
| Calixto, JB; Ferreira, J; Mattos, WM; Niero, R; Richetti, GP; Yunes, RA | 1 |
| Calixto, JB; Claudino, RF; Ferreira, J; Kassuya, CA | 1 |
| Aoi, Y; Fukushima, K; Kato, S; Takeuchi, K | 1 |
| Beyer, CE; Brandt, MR; Smith, VA | 1 |
| Amaya, F; Barrett, L; Lin, CR; Samad, TA; Takada, J; Wang, H; Woolf, CJ | 1 |
| Bülbül, M; Izgüt-Uysal, VN; Ongüt, G; Tan, R; Tosun, O | 1 |
| Colleoni, M; Comelli, F; Costa, B; Giagnoni, G; Trovato, AE | 1 |
| Kakimura, J; Matsutomi, T; Nakamoto, C; Ogata, N; Zheng, T | 1 |
| Berg, KA; Clarke, WP; Hargreaves, KM; Patwardhan, AM; Sanchez, TA; Silva, YM | 1 |
| Laaris, N; Weinreich, D | 1 |
| Cicha, MZ; Kopp, UC; Yorek, MA | 1 |
| Farugia, J; Hargreaves, KM; Patwardhan, AM; Vela, J; Vela, K | 1 |
| Al-Asmar, B; Chidiac, JJ; Jabbur, SJ; Rifai, K; Saadé, NE | 1 |
| Bastos, LC; Tonussi, CR | 1 |
| Fehrenbacher, JC; Hargreaves, KM; Henry, MA; Locke, EE; Sun, XX | 1 |
| Mahmud, A; Nagy, I; Paule, CC; Santha, P | 1 |
| Brzozowski, T; Burnat, G; Engel, M; Gaca, P; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R | 1 |
| Belvisi, MG; Maher, SA | 1 |
| Aihara, E; Ohashi, Y; Okuda, S; Sasaki, Y; Takahashi, K; Takasuka, H; Takeuchi, K | 1 |
| Verkman, AS; Zhang, H | 1 |
| Epple, HJ; Fromm, A; Fromm, M; Pfaffenbach, S; Schulzke, JD; Troeger, H | 1 |
| Cheng, P; Diatchenko, L; Gris, P; Maixner, W; Pierson, J | 1 |
| Aihara, E; Hayashi, S; Ise, F; Koyama, M; Takahashi, K; Takasuka, H; Takeuchi, K | 1 |
| Mlynarczyk, M; Nagy, I; Paule, CC; Soneji, ND | 1 |
| Birklein, F; Fuchs, D; Reeh, PW; Sauer, SK | 1 |
| Bang, S; Cho, H; Hwang, SW; Kim, KY; Lee, SH; Park, JS; Ryu, JJ; Yang, TJ; Yoo, S | 1 |
| Buzas, K; Cohen, JI; Fan, H; Howard, OM; Klinman, D; Mont, E; Oppenheim, JJ; Qi, J; Wang, K | 1 |
| Bachert, C; Derycke, L; Hall, D; Holtappels, G; Timmermans, JP; Van Crombruggen, K; Van Nassauw, L | 1 |
| Henry, PJ; Mann, TS; Taylor, SJ | 1 |
| Ding, L; Gao, S; Hu, JH; Huang, J; Qiu, L; Shi, D; Zhu, QG | 1 |
| Manokawinchoke, J; Pavasant, P; Sooampon, S | 1 |
| Chi, XX; Li, C; Nicol, GD; Strong, JA; Xie, W; Zhang, JM | 1 |
| Belvisi, MG; Birrell, MA; Dubuis, E; Grace, M; Maher, SA | 1 |
| Bavencoffe, A; Dessauer, CW; Efendiev, R; Hu, H; Zhu, MX | 1 |
| Battani, KA; Lindgren, CA; Morford, JJ; Newman, ZL; Ryan, SB; Su, Z | 1 |
| Allgöwer, F; Buschow, R; Diskar, M; Hasenauer, J; Herberg, FW; Hucho, T; Isensee, J; Prinz, A; Waldherr, S | 1 |
| Lü, H; Qiu, Z; Wang, L; Xu, X; Yang, Z; Yu, L | 1 |
| Avelino, A; Buluwela, L; Jenes, A; Mistry, S; Nagy, I; Paule, CC; Photiou, A; Varga, A | 1 |
| Copits, BA; Davidson, S; Gereau, RW; Ghetti, A; Page, G; Zhang, J | 1 |
| Athie, M; Dias, EV; Lamana, SM; Miranda, J; Parada, CA; Tambeli, CH | 1 |
| Belvisi, MG; Birrell, MA; Bonvini, S; Coote, J; Dockry, R; Dubuis, E; Holt, K; Kelsall, A; Khalid, S; Maher, SA; Smith, JA; Woodcock, A; Wortley, MA | 1 |
| Buck, B; Grönniger, E; Holtzmann, U; Jung, KA; Neufang, G; Rippke, F; Schoelermann, AM; Stäb, F; Sulzberger, M; Wenck, H; Worthmann, AC | 1 |
| Fehrenbacher, JC; Hudmon, A; Malty, RH; Vasko, MR | 1 |
| Kim, YN; Ma, W; Rudakou, U; St-Jacques, B | 1 |
| Bhatia, HS; Fiebich, BL; Muñoz, E; Roelofs, N | 1 |
| Gao, JQ; Gao, SQ; Hu, ZJ; Li, LJ; Niu, XQ; Wang, XR; Ying, XY | 1 |
| Atmaramani, R; Black, BJ; Campbell, ZT; Dussor, G; Kumaraju, R; Pancrazio, JJ; Plagens, S; Price, TJ; Romero-Ortega, M | 1 |
| Gao, X; Wei, W; Xu, F; Zhao, L; Zhuang, J | 1 |
| Cai, M; Ding, Y; Li, H; Li, S; Li, Y; Sun, Q; Xie, W; Zhang, Y | 1 |
| Ma, H; Mao, R; Tang, Y; Yan, H; Zhang, Y; Zhao, Y | 1 |
5 trial(s) available for capsaicin and dinoprostone
| Article | Year |
|---|---|
Contrasting effects of prostaglandins E2 and F2 alpha on sensitivity of the human cough reflex.
Topics: Adolescent; Adult; Capsaicin; Chlorides; Citrates; Citric Acid; Cough; Dinoprost; Dinoprostone; Double-Blind Method; Female; Humans; Male; Nerve Fibers; Reflex | 1992 |
Eicosanoid and cytokine levels in acute skin irritation in response to tape stripping and capsaicin.
Topics: Acute Disease; Adhesives; Capsaicin; Cytokines; Dermatitis, Irritant; Dinoprostone; Eicosanoids; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Leukotriene B4; Skin; Tumor Necrosis Factor-alpha | 1999 |
Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens.
Topics: Acetylcholine; Adult; Bradykinin; Capsaicin; Dinoprostone; Electric Stimulation; Female; Histamine; Humans; Inflammation Mediators; Male; Microdialysis; Nerve Fibers, Unmyelinated; Nociceptors; Pain; Pain Measurement; Peroneal Nerve; Pruritus; Psychophysics; Reflex; Sensory Thresholds; Serotonin; Skin; Sympathetic Nervous System | 2003 |
Capsaicin-evoked iCGRP release from human dental pulp: a model system for the study of peripheral neuropeptide secretion in normal healthy tissue.
Topics: Adolescent; Adult; Biological Assay; Biopsy; Calcitonin Gene-Related Peptide; Capsaicin; Dental Pulp; Dinoprostone; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Models, Biological; Models, Neurological; Nociceptors; Pain; Receptors, Opioid, mu; Sensory Receptor Cells; Sensory System Agents; Tetradecanoylphorbol Acetate; TRPV Cation Channels; Young Adult | 2009 |
Effective treatment for sensitive skin: 4-t-butylcyclohexanol and licochalcone A.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Capsaicin; Cell Line; Chalcones; Cyclohexanols; Dinoprostone; Dipeptides; Dose-Response Relationship, Drug; Drug Combinations; Erythema; Facial Dermatoses; Female; Humans; Male; Middle Aged; Neurons; NF-kappa B; Pain; Sensation Disorders; Signal Transduction; Single-Blind Method; Skin Cream; Swine; TRPV Cation Channels; Young Adult | 2016 |
138 other study(ies) available for capsaicin and dinoprostone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids.
Topics: Analgesics; Animals; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Pain; Pain Threshold; Rats; Transient Receptor Potential Channels | 2017 |
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation | 1992 |
Modulation by opioids and by afferent sensory neurones of prostanoid protection of the rat gastric mucosa.
Topics: Animals; Capsaicin; Dinoprostone; Ethanol; Gastric Mucosa; Male; Morphine; Naloxone; Narcotics; Neurons, Afferent; Prostaglandins; Rats; Rats, Inbred Strains | 1992 |
The mediation of increased duodenal alkaline secretion in response to 10 mM HCl in the anaesthetized rat. Support for the involvement of capsaicin-sensitive nerve elements.
Topics: Animals; Bicarbonates; Capsaicin; Dinoprostone; Duodenum; Hydrochloric Acid; Intestinal Mucosa; Lidocaine; Male; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Vagotomy; Vagus Nerve | 1992 |
Bradykinin modulation of a spinal nociceptive reflex in the rat.
Topics: Analysis of Variance; Animals; Blood Pressure; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Heart Rate; Methysergide; Nociceptors; Pain; Phentolamine; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Vagus Nerve | 1992 |
Effects of capsaicin on the metabolism of rheumatoid arthritis synoviocytes in vitro.
Topics: Arthritis, Rheumatoid; Capsaicin; Cell Division; Cells, Cultured; Dinoprostone; DNA; Dose-Response Relationship, Drug; Humans; Microbial Collagenase; RNA; Stimulation, Chemical; Synovial Fluid | 1990 |
Prostaglandins sensitize nociceptors in cell culture.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Capsaicin; Cells, Cultured; Dinoprostone; Epoprostenol; Evoked Potentials; Ganglia, Spinal; Membrane Potentials; Neurons; Nociceptors; Rats | 1991 |
Arachidonic acid and bradykinin share a common pathway to release neuropeptide from capsaicin-sensitive sensory nerve fibers of the guinea pig heart.
Topics: Animals; Arachidonic Acid; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; Eicosanoids; Epoprostenol; Guinea Pigs; Heart; In Vitro Techniques; Nerve Fibers; Neurons, Afferent; Perfusion | 1991 |
Afferent nerve-mediated protection against deep mucosal damage in the rat stomach.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Dinoprostone; Ethanol; Female; Gastric Mucosa; Male; Microscopy, Electron, Scanning; Neurons, Afferent; Rats; Rats, Inbred Strains; Regional Blood Flow; Stimulation, Chemical | 1990 |
Effect of topical capsaicin on the cutaneous responses to inflammatory mediators and to antigen in man.
Topics: Administration, Topical; Adult; Allergens; Capsaicin; Dinoprostone; Double-Blind Method; Histamine Release; Humans; Hypersensitivity; Hypersensitivity, Immediate; Neuropeptides; Platelet Activating Factor | 1989 |
Sensitivity of the human cough reflex: effect of inflammatory mediators prostaglandin E2, bradykinin, and histamine.
Topics: Adult; Airway Resistance; Bradykinin; Capsaicin; Citrates; Citric Acid; Cough; Dinoprostone; Female; Histamine; Humans; Male; Reflex; Sensory Receptor Cells | 1989 |
Leukotriene and prostaglandin sensitization of cutaneous high-threshold C- and A-delta mechanonociceptors in the hairy skin of rat hindlimbs.
Topics: Afferent Pathways; Animals; Bradykinin; Capsaicin; Differential Threshold; Dinoprostone; Hair; Hindlimb; Leukotriene B4; Male; Mechanoreceptors; Nerve Fibers; Nociceptors; Prostaglandins E; Rats; Skin | 1987 |
Prostanoids modulate reflex micturition by acting through capsaicin-sensitive afferents.
Topics: Animals; Capsaicin; Dinoprostone; Indomethacin; Male; Prostaglandins E; Rats; Reflex; Thromboxane B2; Urinary Bladder; Urination | 1988 |
Inhibition of human neutrophil 5-lipoxygenase activity by gingerdione, shogaol, capsaicin and related pungent compounds.
Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Capsaicin; Catechols; Dinoprostone; Fatty Alcohols; Guaiacol; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxygenase Inhibitors; Neutrophils; Plant Extracts; Prostaglandins E | 1986 |
Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons.
Topics: Animals; Capsaicin; Cysteamine; Dinoprostone; Duodenal Ulcer; Epoprostenol; Ethanol; Female; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer | 1986 |
Some rat sensory neurons in culture express characteristics of differentiated pain sensory cells.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Cell Differentiation; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Neurons; Pain; Prostaglandins E; Rats; Substance P; Trigeminal Nerve | 1983 |
Ocular responses evoked by capsaicin and prostaglandin E2 are inhibited by a substance P antagonist.
Topics: Animals; Aqueous Humor; Capsaicin; Dinoprostone; Fatty Acids, Unsaturated; Prostaglandins E; Pupil; Rabbits; Substance P; Tetrodotoxin | 1983 |
Potentiating effects of prostaglandin E2 on bradykinin and capsaicin responses in medial thalamic nociceptive neurons.
Topics: Action Potentials; Animals; Aspirin; Bradykinin; Capsaicin; Cats; Dinoprostone; Drug Synergism; Fatty Acids, Unsaturated; Hypothalamus; Hypothalamus, Middle; Neurons; Nociceptors; Prostaglandins E | 1982 |
The non-peptide NK1 receptor antagonist SR140333 produces long-lasting inhibition of neurogenic inflammation, but does not influence acute chemo- or thermonociception in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Capillary Permeability; Capsaicin; Dinoprostone; Female; Hot Temperature; Injections, Intravenous; Injections, Subcutaneous; Male; Motor Activity; Nerve Tissue; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Pain Measurement; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley | 1995 |
Role of gastric blood flow in impaired defense and repair of aged rat stomachs.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; Ethanol; Gastric Mucosa; Hemodynamics; Hydrogen; Immunohistochemistry; Leukotriene C4; Male; Nerve Fibers; Osmolar Concentration; Rats; Rats, Inbred F344; Regional Blood Flow; Sodium Chloride; Stomach | 1995 |
Roles of prostaglandins, nitric oxide and the capsaicin-sensitive sensory nerves in gastroprotection produced by ecabet sodium.
Topics: 16,16-Dimethylprostaglandin E2; Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arginine; Capsaicin; Dinoprostone; Diterpenes; Drug Interactions; Ethanol; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Neurons, Afferent; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 1995 |
Role of endogenous gastrin in gastroprotection.
Topics: Animals; Aspirin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Mucosa; Gastrin-Releasing Peptide; Gastrins; Male; Neurons, Afferent; Nitric Oxide; Peptides; Peptones; Rats; Rats, Wistar; Stomach Diseases | 1995 |
Effects of prostaglandin E2 and capsaicin on behavior and cerebrospinal fluid amino acid concentrations of unanesthetized rats: a microdialysis study.
Topics: Amino Acids; Animals; Behavior, Animal; Capsaicin; Dinoprostone; Male; Microdialysis; Osmolar Concentration; Rats; Rats, Sprague-Dawley | 1995 |
Capsaicin-evoked prostaglandin E2 release in spinal cord slices: relative effect of cyclooxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; In Vitro Techniques; Male; Proteins; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
Intracisternal thyrotropin-releasing hormone-induced vagally mediated gastric protection against ethanol lesions: central and peripheral mechanisms.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; Ethanol; Gastric Acid; Gastric Mucosa; Injections, Intraventricular; Neurons, Afferent; Nitric Oxide; Pyrrolidonecarboxylic Acid; Rats; Stomach; Stomach Ulcer; Thyrotropin-Releasing Hormone; Vagus Nerve | 1994 |
Capsaicin-induced gastric mucosal hyperemia and protection: the role of calcitonin gene-related peptide.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; DNA; Gastric Mucosa; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1994 |
Bradykinin-induced sensitization of afferent neurons in the rat paw.
Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Electrophysiology; Female; Foot; Ganglia, Sympathetic; Hot Temperature; Hyperesthesia; Male; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley; Sensory Thresholds | 1994 |
Effects of aerosol-applied capsaicin, histamine and prostaglandin E2 on airway sensory receptors of anaesthetized cats.
Topics: Administration, Inhalation; Anesthesia; Animals; Bronchoconstriction; Capsaicin; Cats; Dinoprostone; Histamine; Injections, Intravenous; Lung; Male; Mechanoreceptors; Nerve Fibers; Nerve Fibers, Myelinated; Neural Conduction; Respiration, Artificial; Respiratory Mechanics; Sensory Receptor Cells; Vagus Nerve | 1993 |
The effects of capsaicin, bradykinin, PGE2 and cicaprost on the discharge of articular sensory receptors in vitro.
Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Epoprostenol; In Vitro Techniques; Male; Mechanoreceptors; Neurons; Rats; Rats, Wistar; Sensory Receptor Cells; Tarsus, Animal | 1993 |
Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors.
Topics: Adenosine; Animals; Capsaicin; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Hyperalgesia; Kinetics; Male; Membrane Potentials; Neurons; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Serotonin; Sodium Channels; Tetrodotoxin; Thromboxane B2 | 1996 |
Pulmonary chemoreflex sensitivity is enhanced by prostaglandin E2 in anesthetized rats.
Topics: Analysis of Variance; Animals; Biguanides; Capsaicin; Chemoreceptor Cells; Dinoprostone; Female; Hypoglycemic Agents; Lung; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Vagus Nerve | 1995 |
Sodium nonivamide acetate: a non-pungently antinociceptive capsaicin derivative with unusual anti-inflammatory properties.
Topics: Animals; Bradykinin; Capsaicin; Dermatologic Agents; Dinoprostone; Humans; Mice; Pain; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Wistar; Tail; Thromboxane B2; Thromboxane-A Synthase | 1996 |
Co-expression of nociceptor properties in dorsal root ganglion neurons from the adult rat in vitro.
Topics: Action Potentials; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Immunohistochemistry; Male; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
Neonatal capsaicin attenuates mechanical nociception in the rat.
Topics: Alprostadil; Animals; Animals, Newborn; Capsaicin; Conditioning, Psychological; Data Interpretation, Statistical; Dinoprostone; Male; Mechanoreceptors; Neurons, Afferent; Nociceptors; Oxytocics; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1996 |
Excitatory effects of algesic compounds on neuronal processes in murine dorsal root ganglion cell culture.
Topics: Action Potentials; Animals; Bradykinin; Capsaicin; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Mice; Neurons; Pain; Patch-Clamp Techniques; Tetrodotoxin | 1997 |
Neonatal capsaicin treatment abolishes formalin-induced spinal PGE2 release.
Topics: Amino Acids; Animals; Animals, Newborn; Capsaicin; Dinoprostone; Formaldehyde; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 1997 |
5HT4 receptors couple positively to tetrodotoxin-insensitive sodium channels in a subpopulation of capsaicin-sensitive rat sensory neurons.
Topics: Animals; Capsaicin; Dinoprostone; Electric Conductivity; Ganglia, Spinal; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Channels; Tetrodotoxin | 1997 |
Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase.
Topics: Animals; Capsaicin; Cyclic AMP-Dependent Protein Kinase RIbeta Subunit; Cyclic AMP-Dependent Protein Kinases; Differential Threshold; Dinoprostone; Gene Expression; Gene Targeting; Hot Temperature; Isoenzymes; Mice; Mice, Mutant Strains; Mutation; Neuritis; Nociceptors; Pain; Sciatic Nerve; Sensory Thresholds; Transgenes; Wounds, Nonpenetrating | 1997 |
Algesics excite axotomised afferent nerve fibres within the first hours following nerve transection in rats.
Topics: Afferent Pathways; Animals; Axotomy; Bradykinin; Capsaicin; Dinoprostone; Female; Inflammation Mediators; Male; Nerve Fibers; Rats; Rats, Wistar; Saline Solution, Hypertonic; Stimulation, Chemical; Time Factors | 1997 |
Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capsaicin; Collagenases; Curcumin; Dinoprostone; Hyaluronoglucosaminidase; Leukotriene B4; Leukotriene C4; Lysosomes; Macrophages, Peritoneal; Male; Membrane Lipids; Pancreatic Elastase; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1997 |
Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons.
Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Neurons, Afferent; Nitric Oxide; Patch-Clamp Techniques; Rats; Stimulation, Chemical | 1997 |
Inflammatory mediators at acidic pH activate capsaicin receptors in cultured sensory neurons from newborn rats.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Cells, Cultured; Coculture Techniques; Dinoprostone; Drug Synergism; Ganglia, Spinal; Hippocampus; Hydrogen-Ion Concentration; Inflammation; Ion Channel Gating; Neuroglia; Neurons, Afferent; Rats; Receptors, Drug; Serotonin; Stimulation, Chemical | 1998 |
The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: whole-cell and single-channel studies.
Topics: Animals; Capsaicin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Electric Conductivity; Ion Channel Gating; Ion Channels; Neurons, Afferent; Osmolar Concentration; Rats; Rats, Sprague-Dawley | 1998 |
Substance P and capsaicin release prostaglandin E2 from rat intrapulmonary bronchi.
Topics: Animals; Bronchi; Capsaicin; Dinoprostone; Epithelial Cells; In Vitro Techniques; Indoles; Isoindoles; Male; Meclofenamic Acid; Models, Biological; Muscle, Smooth; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Substance P | 1998 |
Gastric cytoprotection is secondary to increased mucosal fluid secretion: a study of six cytoprotective agents in the rat.
Topics: Animals; Anti-Ulcer Agents; Capsaicin; Cytoprotection; Cytotoxins; Dinoprostone; Ethylmaleimide; Female; Gastric Mucosa; Hydrochloric Acid; Male; Misoprostol; Nicotine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Rioprostil | 1998 |
Involvement of endogenous cholecystokinin and somatostatin in gastroprotection induced by intraduodenal fat.
Topics: Animals; Capsaicin; Cholecystokinin; Denervation; Dinoprostone; Dopamine Agents; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Hormone Antagonists; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oleic Acid; Pepsin A; Proglumide; Rats; Rats, Wistar; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide; Somatostatin; Stomach Ulcer; Vagotomy | 1998 |
The role of prostaglandins in the bradykinin-induced activation of serosal afferents of the rat jejunum in vitro.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Electrophysiology; Extracellular Space; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Naproxen; Neurons, Afferent; Patch-Clamp Techniques; Physical Stimulation; Prostaglandins; Rats; Stimulation, Chemical | 1999 |
The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Capsaicin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Excipients; Hindlimb; Hyperalgesia; Inflammation; Inflammation Mediators; Male; Nociceptors; Oxytocics; Pain; Pain Threshold; Rats; Rats, Wistar; Thionucleotides; Ultraviolet Rays | 1999 |
Response properties of trigeminal brain stem neurons with input from dura mater encephali in the rat.
Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Dura Mater; Electric Stimulation; Histamine; Inflammation; Male; Mechanoreceptors; Microelectrodes; Neurons; Rats; Rats, Wistar; Serotonin; Trigeminal Nuclei; Trigeminal Nucleus, Spinal | 1999 |
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Carrageenan; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; In Vitro Techniques; Inflammation; Knee Joint; Male; N-Methylaspartate; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Thromboxane B2 | 1999 |
Involvement of primary afferent C-fibres in touch-evoked pain (allodynia) induced by prostaglandin E2.
Topics: Afferent Pathways; Animals; Capsaicin; Dinoprostone; Electrophysiology; Hot Temperature; Hyperesthesia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Nerve Fibers; Neurons; Pain; Physical Stimulation; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Touch | 1999 |
Rat peripheral nerve components release calcitonin gene-related peptide and prostaglandin E2 in response to noxious stimuli: evidence that nervi nervorum are nociceptors.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dinoprostone; Electric Stimulation; Inflammation Mediators; Male; Nociceptors; Pain; Peripheral Nerves; Rats; Rats, Wistar; Ruthenium Red; Stimulation, Chemical | 1999 |
Oral antinociception and oedema inhibition produced by NPC 18884, a non-peptidic bradykinin B2 receptor antagonist.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Behavior, Animal; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; Carrageenan; Dinoprostone; Dipeptides; Dose-Response Relationship, Drug; Edema; Formaldehyde; Hindlimb; Hyperalgesia; Injections, Intraperitoneal; Male; Mice; Pain; Rats; Rats, Wistar; Receptor, Bradykinin B2; Time Factors | 1999 |
Capsaicin sensitivity and voltage-gated sodium currents in colon sensory neurons from rat dorsal root ganglia.
Topics: Action Potentials; Adenosine; Analgesics; Animals; Bradykinin; Capsaicin; Carbocyanines; Colon; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Fluorescent Dyes; Ganglia, Spinal; Histamine; Ion Channel Gating; Male; Neurons, Afferent; Pain; Rats; Rats, Sprague-Dawley; Serotonin; Sodium; Sodium Channels; Tetrodotoxin | 1999 |
Effect of malotilate on ethanol-induced gastric mucosal damage in capsaicin-pretreated rats.
Topics: Animals; Anti-Ulcer Agents; Capsaicin; Dinoprostone; Ethanol; Gastric Mucosa; Male; Malonates; Neurons, Afferent; Rats; Rats, Wistar | 1999 |
Interactions of inflammatory mediators and low pH not influenced by capsazepine in rat cutaneous nociceptors.
Topics: Animals; Bradykinin; Capsaicin; Dinoprostone; Drug Interactions; Ganglia, Spinal; Hydrogen-Ion Concentration; Inflammation; Inflammation Mediators; Male; Nerve Fibers; Nociceptors; Oxytocics; Protons; Rats; Rats, Wistar; Serotonin; Signal Transduction; Skin | 2000 |
Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances.
Topics: Animals; Capsaicin; Cell Line; Cells, Cultured; Dinoprostone; Eicosanoids; Ganglia, Spinal; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Ion Channel Gating; Leukotriene B4; Leukotrienes; Ligands; Lipid Peroxides; Lipoxygenase; Molecular Structure; Neurons, Afferent; Prostaglandin D2; Prostaglandin H2; Prostaglandins H; Rats; Receptors, Drug; Structure-Activity Relationship | 2000 |
Prostaglandin E(2)-mediated sensitization of rat sensory neurons is not altered by nerve growth factor.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic AMP; Dinoprostone; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Nerve Growth Factor; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley | 2000 |
Inflammatory mediators release calcitonin gene-related peptide from dorsal root ganglion neurons of the rat.
Topics: Acids; Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Dinoprostone; Female; Free Radical Scavengers; Ganglia, Spinal; Hydrogen-Ion Concentration; Inflammation Mediators; Kallidin; Male; Neurons; Rats; Rats, Wistar; Receptors, Drug; Serotonin; Stimulation, Chemical | 2000 |
Prostaglandin E(2) enhances chemical and mechanical sensitivities of pulmonary C fibers in the rat.
Topics: Animals; Capsaicin; Dinoprostone; Lung; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Vagus Nerve | 2000 |
Sensory pathways and cyclooxygenase regulate mucus gel thickness in rat duodenum.
Topics: Animals; Bradykinin; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Enzyme Inhibitors; Injections, Intravenous; Intestinal Mucosa; Mucus; Perfusion; Prostaglandin-Endoperoxide Synthases; Rats; Signal Transduction | 2001 |
Antinociceptive effects of delta-opioid agonists in Rhesus monkeys: effects on chemically induced thermal hypersensitivity.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Freund's Adjuvant; Hyperalgesia; Ketorolac; Macaca mulatta; Male; Morphine; Pain; Pain Measurement; Piperazines; Receptors, Opioid, delta | 2001 |
Characterization of the glutamatergic system for induction and maintenance of allodynia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; ATP-Binding Cassette Transporters; Capsaicin; Dinoprost; Dinoprostone; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain; Pain Measurement; Physical Stimulation; Posterior Horn Cells; Receptors, Glutamate; Synapses; Synaptic Transmission; Touch | 2001 |
Influence of the epithelium on acetylcholine release from parasympathetic nerves of the rat trachea.
Topics: Acetylcholine; Animals; Capsaicin; Carbachol; Dinoprostone; Epithelium; Female; In Vitro Techniques; Male; Muscarinic Agonists; Neuropeptides; Neurotransmitter Agents; Nitric Oxide; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Cholinergic; Superoxides; Trachea; Vasoactive Intestinal Peptide | 2000 |
The effects of capsaicin cream on prostaglandin-induced allodynia.
Topics: Animals; Capsaicin; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Male; Mice; Nerve Fibers; Ointments; Pain; Reaction Time; Receptors, N-Methyl-D-Aspartate | 2001 |
Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves.
Topics: Adenosine; Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Digestive System; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Sulfones; Theophylline; Time Factors | 2001 |
Capsaicin-evoked CGRP release from rat buccal mucosa: development of a model system for studying trigeminal mechanisms of neurogenic inflammation.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Inflammation Mediators; Ionophores; Male; Mouth Mucosa; Neurogenic Inflammation; Nociceptors; Organ Culture Techniques; Pain Measurement; Potassium Chloride; Rats; Rats, Sprague-Dawley; Serotonin; Trigeminal Nerve | 2001 |
Effects of PGE(2) on neurons from rat dorsal root ganglia in intact and adjuvant-inflamed rats: role of NGF on PGE(2)-induced depolarization.
Topics: Action Potentials; Animals; Arthritis, Experimental; Bradykinin; Capsaicin; Cells, Cultured; Dinoprostone; Freund's Adjuvant; Ganglia, Spinal; Inflammation; Male; Nerve Growth Factor; Neurons, Afferent; Rats; Rats, Wistar; Sensory Thresholds; Tachyphylaxis | 2001 |
Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L-tryptophan.
Topics: Actins; Animals; Capsaicin; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Gastrins; Male; Melatonin; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Regional Blood Flow; Stomach Ulcer; Tryptamines; Tryptophan | 2002 |
Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Capsaicin; Colforsin; Dinoprostone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GTP-Binding Protein alpha Subunits, Gi-Go; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neurons, Afferent; Pain Measurement; Pertussis Toxin; Phosphorylation; Proline; Receptors, Drug; Receptors, Metabotropic Glutamate; Virulence Factors, Bordetella | 2002 |
Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia.
Topics: Animals; Behavior, Animal; Capsaicin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Dinoprostone; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hyperalgesia; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain Measurement; Patch-Clamp Techniques; Phospholipids; Prostaglandins; Protein Kinase C; Receptor, Metabotropic Glutamate 5; Receptors, Drug; Receptors, Metabotropic Glutamate; Signal Transduction; Type C Phospholipases | 2002 |
Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes.
Topics: Calcium; Calcium Signaling; Capsaicin; Cell Line; Cyclooxygenase 2; Dinoprostone; Humans; Immunoblotting; Inflammation Mediators; Interleukin-8; Isoenzymes; Keratinocytes; Membrane Proteins; Physical Stimulation; Prostaglandin-Endoperoxide Synthases; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin | 2003 |
Differences in gastroprotective processes in 6- to 8- and 14- to 16-week-old rats.
Topics: Age Factors; Animals; Capsaicin; Dinoprostone; Ethanol; Gastric Mucosa; Male; Opioid Peptides; Rats; Rats, Wistar | 2002 |
Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Receptors, Drug; RNA, Messenger; TRPV Cation Channels | 2003 |
Flurbiprofen inhibits capsaicin induced calcitonin gene related peptide release from rat spinal cord via an endocannabinoid dependent mechanism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Dronabinol; Endocannabinoids; Fatty Acids, Unsaturated; Flurbiprofen; Immunoassay; In Vitro Techniques; Phospholipases A; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Spinal Cord | 2003 |
Ca2+ transient evoked by chemical stimulation is enhanced by PGE2 in vagal sensory neurons: role of cAMP/PKA signaling pathway.
Topics: Adenosine Triphosphate; Animals; Calcium; Capsaicin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Male; Neurons, Afferent; Nodose Ganglion; Potassium Chloride; Rats; Rats, Sprague-Dawley; Signal Transduction; Stimulation, Chemical; Thionucleotides | 2003 |
Signal transduction for inhibition of inducible nitric oxide synthase and cyclooxygenase-2 induction by capsaicin and related analogs in macrophages.
Topics: Animals; Capsaicin; Cell Line; Cyclooxygenase 2; Dinoprostone; Diterpenes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Ganglia, Spinal; I-kappa B Kinase; Interferon-gamma; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Male; Mitogen-Activated Protein Kinases; Neurotoxins; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Drug; RNA, Messenger; Signal Transduction; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1 | 2003 |
Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide.
Topics: Aminobutyrates; Animals; Arachidonic Acid; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Dinoprostone; Diterpenes; Dopamine; Endocannabinoids; Ganglia, Spinal; Male; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Drug; Staurosporine; Trigeminal Ganglion; TRPC Cation Channels; TRPV Cation Channels | 2004 |
Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.
Topics: Administration, Oral; Animals; Body Weight; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Acid; Gastric Mucosa; Gastritis; Gene Expression; Indomethacin; Injections, Subcutaneous; Iodoacetamide; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach Ulcer; Sulfones; Vagotomy | 2004 |
Participation of prostaglandin E receptor EP4 subtype in duodenal bicarbonate secretion in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bicarbonates; Capsaicin; Dinoprostone; Drug Combinations; Duodenum; Hydrochloric Acid; Male; Methyl Ethers; Naphthalenes; Phenylbutyrates; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Verapamil | 2004 |
Regulation of calcitonin gene-related peptide release from rat trigeminal nucleus caudalis slices in vitro.
Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; In Vitro Techniques; Indomethacin; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Trigeminal Caudal Nucleus | 2004 |
Ischemic preconditioning of remote organs attenuates gastric ischemia-reperfusion injury through involvement of prostaglandins and sensory nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Dinoprostone; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Sulfones; Tumor Necrosis Factor-alpha | 2004 |
Prostaglandin E2 potentiates a TTX-resistant sodium current in rat capsaicin-sensitive vagal pulmonary sensory neurones.
Topics: Animals; Capsaicin; Dinoprostone; Drug Synergism; Lung; Male; Membrane Potentials; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin; Vagus Nerve | 2005 |
Mechanisms underlying capsaicin-stimulated secretion in the stomach: comparison with mucosal acidification.
Topics: Animals; Bicarbonates; Bradykinin; Capsaicin; Dinoprostone; Gastric Mucosa; Hydrogen-Ion Concentration; Male; Mice; Nitric Oxide; Nitro Compounds; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol | 2005 |
Characteristics of propofol-evoked vascular pain in anaesthetized rats.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Animals; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Electromyography; Indomethacin; Injections, Intra-Arterial; Male; Muscle, Skeletal; Pain; Procaine; Propofol; Rats; Rats, Sprague-Dawley; Reflex | 2005 |
Inflammatory mediators convert anandamide into a potent activator of the vanilloid type 1 transient receptor potential receptor in nociceptive primary sensory neurons.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Bradykinin; Capsaicin; Cells, Cultured; Cobalt; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Endocannabinoids; Enzyme Inhibitors; Inflammation Mediators; Neurons, Afferent; Nociceptors; Polyunsaturated Alkamides; Protein Kinase C; Rats; Rats, Sprague-Dawley; TRPV Cation Channels; Type C Phospholipases | 2005 |
Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Asthma; Blood Pressure; Bradykinin; Capsaicin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Guinea Pigs; Heart Rate; Indomethacin; Lung; Nerve Fibers, Unmyelinated; Prostaglandins; Respiratory Hypersensitivity; Substance P | 2006 |
Antinociceptive properties produced by the pregnane compound velutinol A isolated from Mandevilla velutina.
Topics: Analgesics; Animals; Apocynaceae; Bradykinin; Capsaicin; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Diterpenes; Male; Mice; Pain Measurement; Plant Extracts; Pregnanes; Tetradecanoylphorbol Acetate | 2006 |
Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema.
Topics: Actins; Animals; Animals, Newborn; Blotting, Western; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Edema; Enzyme Inhibitors; Foot; GTP-Binding Proteins; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Protein Kinase C; Receptors, Prostaglandin E; Signal Transduction | 2006 |
Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Acetamides; Animals; Calcium; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Histamine H2 Antagonists; Humans; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Piperidines; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Stomach; Stomach Diseases; TRPV Cation Channels | 2006 |
Neurochemical changes in the RVM associated with peripheral inflammatory pain stimuli.
Topics: Analysis of Variance; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Capsaicin; Chromatography, High Pressure Liquid; Dinoprostone; Drug Interactions; Electrochemistry; Hot Temperature; Male; Medulla Oblongata; Microdialysis; Morphine; Narcotics; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time | 2006 |
Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity.
Topics: Animals; Biphenyl Compounds; Blotting, Western; Capsaicin; Cells, Cultured; Dinoprostone; Electrophysiology; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Hybridization; Inflammation; Injections, Spinal; Male; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Small Interfering | 2006 |
Prostaglandins, capsaicin-sensitive sensory nerves and neutrophil infiltration, but not nitric oxide, contribute to cold restraint stress-induced gastric adaptation in rats.
Topics: Acclimatization; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cold Temperature; Dinoprostone; Gastric Mucosa; Indomethacin; Male; Neurons, Afferent; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Prostaglandins; Rats; Rats, Wistar; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Physiological; Thermosensing | 2006 |
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain.
Topics: Administration, Oral; Animals; Cannabidiol; Cannabinoid Receptor Antagonists; Cannabis; Capsaicin; Chronic Disease; Dinoprostone; Freund's Adjuvant; Hyperalgesia; Inflammation; Lipid Peroxides; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar; Sciatic Neuropathy; Tumor Necrosis Factor-alpha | 2007 |
Prostaglandin E2 has no effect on two components of tetrodotoxin-resistant Na+ current in mouse dorsal root ganglion.
Topics: Animals; Capsaicin; Cells, Cultured; Dinoprostone; Drug Resistance; Ganglia, Spinal; Mice; NAV1.8 Voltage-Gated Sodium Channel; Nystatin; Sodium; Sodium Channels; Tetrodotoxin | 2007 |
Rapid modulation of micro-opioid receptor signaling in primary sensory neurons.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Arachidonic Acid; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Gene Expression; Inositol Phosphates; Male; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptor, PAR-2; Receptors, Opioid, mu; Signal Transduction; Type C Phospholipases | 2007 |
Prostaglandin E2 depresses solitary tract-mediated synaptic transmission in the nucleus tractus solitarius.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Capsaicin; Dinoprostone; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Neural Inhibition; Oxytocics; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Synaptic Transmission | 2007 |
Impaired responsiveness of renal sensory nerves in streptozotocin-treated rats and obese Zucker diabetic fatty rats: role of angiotensin.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Baroreflex; Capsaicin; Diabetes Mellitus, Experimental; Dinoprostone; Kidney; Losartan; Male; Mechanoreceptors; Neurons, Afferent; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Substance P | 2008 |
Trigeminal nociceptors express prostaglandin receptors.
Topics: Alprostadil; Animals; Capsaicin; Cell Size; Cells, Cultured; Dinoprostone; Exocytosis; Immunohistochemistry; In Situ Hybridization; Male; Neurons; Neuropeptides; Nociceptors; Prostaglandins E, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Trigeminal Ganglion; TRPV Cation Channels | 2008 |
Inflammatory mediators released following application of irritants on the rat injured incisors. The effect of treatment with anti-inflammatory drugs.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Capsaicin; Celecoxib; Dexamethasone; Dinoprostone; Endotoxins; Incisor; Indomethacin; Inflammation Mediators; Irritants; Morphine; Nerve Growth Factor; Pyrazoles; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sulfonamides | 2009 |
PGE(2)-induced lasting nociception to heat: evidences for a selective involvement of A-delta fibres in the hyperpathic component of hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Dimethyl Sulfoxide; Dinoprostone; Hot Temperature; Hyperalgesia; Indomethacin; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Nociceptors; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar | 2010 |
Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons.
Topics: Animals; Arachidonic Acids; Bradykinin; Capsaicin; Cations, Divalent; Cells, Cultured; Cobalt; Dinoprostone; Dronabinol; Endocannabinoids; Female; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; TRPV Cation Channels | 2009 |
Ghrelin ameliorates colonic inflammation. Role of nitric oxide and sensory nerves.
Topics: Animals; Capsaicin; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dinoprostone; Ghrelin; Humans; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase Type II; PPAR gamma; Rats; RNA, Messenger; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation | 2009 |
Prostanoids and the cough reflex.
Topics: Animals; Capsaicin; Cough; Dinoprostone; Guinea Pigs; Humans; Prostaglandins; Rats; Receptors, Prostaglandin; Reflex; Sensory System Agents | 2010 |
Stimulation by sparkling water of gastroduodenal HCO3- secretion in rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Afferent Pathways; Amiloride; Animals; Bicarbonates; Capsaicin; Carbonated Beverages; Dinoprostone; Duodenum; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Water | 2009 |
Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons.
Topics: Action Potentials; Animals; Aquaporin 1; Bradykinin; Capsaicin; Cell Line, Tumor; Dinoprostone; Ganglia, Spinal; Gene Expression Regulation; Inflammation; Mice; Mice, Knockout; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Oxytocics; Pain; Pain Management; Perception; Sensory System Agents; Sodium Channels; Vasodilator Agents | 2010 |
Prostaglandin I(2) sensory input into the enteric nervous system during distension-induced colonic chloride secretion in rat colon.
Topics: Animals; Capsaicin; Chlorides; Cholinergic Agents; Colon; Dinoprostone; Enteric Nervous System; Epoprostenol; Interneurons; Intestinal Mucosa; Male; Neurons, Afferent; Physical Stimulation; Pressure; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Nicotinic; Rheology; Serotonin Antagonists; Synaptic Transmission | 2010 |
Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR).
Topics: Alternative Splicing; Animals; Calcium; Capsaicin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Humans; Nitric Oxide; Protein Isoforms; Receptors, Opioid, mu; Sensory System Agents; Signal Transduction | 2010 |
Stimulation of duodenal HCO₃⁻ secretion by hydrogen sulphide in rats: relation to prostaglandins, nitric oxide and sensory neurones.
Topics: Air Pollutants; Alkynes; Animals; Bicarbonates; Capsaicin; Dinoprostone; Duodenum; Enzyme Inhibitors; Glyburide; Glycine; Hydrogen Sulfide; Hypoglycemic Agents; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sensory System Agents; Sulfides | 2011 |
Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators.
Topics: Animals; Arachidonic Acids; Bradykinin; Capsaicin; Cells, Cultured; Cobalt; Dinoprostone; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Inflammation Mediators; Male; Nerve Growth Factor; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; TRPV Cation Channels | 2010 |
Sensitized peripheral nociception in experimental diabetes of the rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; In Vitro Techniques; Male; Nerve Fibers; Nociceptors; Pain Measurement; Pain Threshold; Rats; Reaction Time; Sciatic Nerve; Skin; Streptozocin; Substance P | 2010 |
Laser modulation of heat and capsaicin receptor TRPV1 leads to thermal antinociception.
Topics: Animals; Behavior, Animal; Calcium Channel Blockers; Calcium Signaling; Capsaicin; Dinoprostone; HEK293 Cells; HeLa Cells; Hot Temperature; Humans; Lasers, Solid-State; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Neurons; Nociceptors; Pain; Pain Threshold; Reaction Time; Ruthenium Red; Sensory System Agents; Sensory Thresholds; Thermosensing; Touch; Trigeminal Nerve; TRPV Cation Channels | 2010 |
Painful pathways induced by TLR stimulation of dorsal root ganglion neurons.
Topics: Aminoquinolines; Anilides; Animals; Arachidonic Acids; Blotting, Western; Calcium; Capsaicin; Cells, Cultured; Cinnamates; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Endocannabinoids; Ganglia, Spinal; Humans; Imidazoles; Mice; Microscopy, Confocal; Neurons; Pain; Poly I-C; Polyunsaturated Alkamides; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 9; Toll-Like Receptors; TRPV Cation Channels | 2011 |
Capsaicin-induced vasodilatation in human nasal vasculature is mediated by modulation of cyclooxygenase-2 activity and abrogated by sulprostone.
Topics: Capsaicin; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nasal Mucosa; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype; TRPV Cation Channels; Vasodilation | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones | 2012 |
Transient receptor potential vanilloid-1 participates in the inhibitory effect of ginsenoside Rg1 on capsaicin-induced interleukin-8 and prostaglandin E2 production in HaCaT cells.
Topics: Calcium; Capsaicin; Cells, Cultured; Central Nervous System Agents; Cyclooxygenase 2; Dinoprostone; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Ginsenosides; HEK293 Cells; Humans; Interleukin-8; Keratinocytes; NF-kappa B; TRPV Cation Channels | 2012 |
Transient receptor potential vanilloid-1 regulates osteoprotegerin/RANKL homeostasis in human periodontal ligament cells.
Topics: 3T3 Cells; Animals; Bone Remodeling; Calcium; Capsaicin; Cell Culture Techniques; Chelating Agents; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Estrenes; Homeostasis; Humans; Mice; Osteoblasts; Osteoprotegerin; Periodontal Ligament; Phosphodiesterase Inhibitors; Pyrrolidinones; RANK Ligand; TRPV Cation Channels; Type C Phospholipases | 2013 |
Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor.
Topics: Action Potentials; Analysis of Variance; Anilides; Animals; Capsaicin; Cell Line, Tumor; Cell Movement; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Guanosine Diphosphate; Hyperalgesia; Lysophospholipids; Male; Melanoma; Mice; Organophosphonates; Pain Threshold; Patch-Clamp Techniques; Pertussis Toxin; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sensory Receptor Cells; Sensory System Agents; Sphingosine; Thionucleotides; Time Factors; Wound Healing | 2012 |
Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin.
Topics: Acrolein; Adult; Aged; Animals; Antitussive Agents; Bradykinin; Calcium; Capsaicin; Cough; Dinoprostone; Female; Guinea Pigs; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Statistics, Nonparametric; Transient Receptor Potential Channels; Vagus Nerve | 2012 |
Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.
Topics: A Kinase Anchor Proteins; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Capsaicin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Ganglia, Spinal; HEK293 Cells; Humans; Hyperalgesia; Mice; Multiprotein Complexes; Nerve Tissue Proteins; Protein Kinase C; Sensory System Agents; TRPV Cation Channels | 2013 |
Cyclooxygenase-2, prostaglandin E2 glycerol ester and nitric oxide are involved in muscarine-induced presynaptic enhancement at the vertebrate neuromuscular junction.
Topics: Animals; Arachidonic Acids; Benzoates; Capsaicin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endocannabinoids; Glycerides; Imidazoles; Lizards; Miniature Postsynaptic Potentials; Muscarine; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Schwann Cells; Sulfonamides; Thiophenes; Xanthones | 2013 |
Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neurons.
Topics: Animals; Biomarkers; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Cyclic AMP-Dependent Protein Kinase Type I; Cyclosporine; Dinoprostone; Gene Expression Regulation; Male; NAV1.8 Voltage-Gated Sodium Channel; Nociception; Phosphorylation; Primary Cell Culture; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Signal Transduction; TRPV Cation Channels | 2014 |
Capsaicin-sensitive cough receptors in lower airway are responsible for cough hypersensitivity in patients with upper airway cough syndrome.
Topics: Adult; Anesthetics, Local; Capsaicin; Case-Control Studies; Cough; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Histamine; Humans; Hypersensitivity; Hypopharynx; Lidocaine; Male; Middle Aged; Receptors, Calcitonin Gene-Related Peptide; Sputum; Statistics, Nonparametric; TRPV Cation Channels | 2013 |
Prolonged exposure to bradykinin and prostaglandin E2 increases TRPV1 mRNA but does not alter TRPV1 and TRPV1b protein expression in cultured rat primary sensory neurons.
Topics: Animals; Bradykinin; Capsaicin; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Nociceptors; Rats; Rats, Sprague-Dawley; RNA, Messenger; TRPV Cation Channels | 2014 |
Human sensory neurons: Membrane properties and sensitization by inflammatory mediators.
Topics: Action Potentials; Adenosine Triphosphate; Adolescent; Bradykinin; Capsaicin; Cell Membrane; Chloroquine; Dinoprostone; Female; Ganglia, Spinal; Histamine; Humans; Male; Patch-Clamp Techniques; Sensory Receptor Cells; Young Adult | 2014 |
Effect of pain chronification and chronic pain on an endogenous pain modulation circuit in rats.
Topics: Analgesics; Animals; Capsaicin; Chronic Pain; Dinoprostone; Hyperalgesia; Male; Nociception; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, mu; Rotarod Performance Test; Somatostatin | 2015 |
Neurophenotypes in Airway Diseases. Insights from Translational Cough Studies.
Topics: Administration, Inhalation; Adult; Aged; Animals; Capsaicin; Cough; Dinoprostone; Disease Models, Animal; Female; Guinea Pigs; Humans; Male; Middle Aged; Phenotype; Pulmonary Disease, Chronic Obstructive; Respiratory System; Smoke; Vagus Nerve | 2016 |
Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A.
Topics: Adjuvants, Immunologic; Animals; Capsaicin; Cells, Cultured; Chromones; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Eicosanoids; Enzyme Inhibitors; Ganglia, Spinal; Isoquinolines; Male; Morpholines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP4 Subtype; Sensory Receptor Cells; Sensory System Agents; Signal Transduction; Sulfonamides; Time Factors | 2016 |
Stimulating TRPV1 externalization and synthesis in dorsal root ganglion neurons contributes to PGE2 potentiation of TRPV1 activity and nociceptor sensitization.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Hyperalgesia; Male; Neurons; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Sciatic Nerve; TRPV Cation Channels | 2017 |
Alleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE
Topics: Animals; Capsaicin; Cells, Cultured; Cytokines; Dinoprostone; Gene Expression Regulation; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Microglia; Protein Serine-Threonine Kinases; Rats; TRPV Cation Channels | 2017 |
Capsaicin-loaded nanolipoidal carriers for topical application: design, characterization, and in vitro/in vivo evaluation.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carbocyanines; Dermatitis; Dinoprostone; Dose-Response Relationship, Drug; Drug Carriers; Female; Fluorescent Dyes; Lipids; Male; Mice, Inbred ICR; Nanocomposites; Particle Size; Rabbits; Rats; Rats, Sprague-Dawley; Skin Absorption | 2017 |
Adult mouse sensory neurons on microelectrode arrays exhibit increased spontaneous and stimulus-evoked activity in the presence of interleukin-6.
Topics: Action Potentials; Animals; Bradykinin; Capsaicin; Cell Culture Techniques; Cells, Cultured; Dinoprostone; Electric Stimulation; Ganglia, Spinal; Hot Temperature; Inflammation; Inflammation Mediators; Interleukin-6; Male; Mice; Microelectrodes; Nociceptors; Sensory Receptor Cells | 2018 |
Cross-effect of TRPV1 and EP3 receptor on coughs and bronchopulmonary C-neural activities.
Topics: Aminopyridines; Animals; Bronchi; Capsaicin; Citric Acid; Cough; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Guinea Pigs; Ion Channel Gating; Male; Models, Biological; Nerve Fibers, Unmyelinated; Nodose Ganglion; Piperazines; Protein Kinase Inhibitors; Pulmonary Ventilation; Receptors, Prostaglandin E, EP3 Subtype; Sensory Receptor Cells; TRPV Cation Channels; Vagus Nerve | 2021 |
Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis.
Topics: Animals; Capsaicin; Cartilage, Articular; Celecoxib; Dinoprostone; Humans; Mice; Mice, Knockout; Osteoarthritis; Pain | 2022 |
Sprayable NAHAO® hydrogel alleviates pain and accelerates rat oral mucositis wound healing.
Topics: Animals; Capsaicin; Cyclooxygenase 2; Dinoprostone; Fluorouracil; Humans; Hydrogels; Male; Matrix Metalloproteinase 9; Pain; Rats; Rats, Sprague-Dawley; Stomatitis; Wound Healing | 2023 |