capsaicin and dextromethorphan

capsaicin has been researched along with dextromethorphan in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's7 (43.75)18.2507
2000's3 (18.75)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Kamei, J; Kasuya, Y1
Igarashi, H; Kamei, J; Kasuya, Y; Mori, T1
Kontani, H; Koshiura, R1
Aziz, SM; Bolser, DC; Chapman, RW; DeGennaro, FC; Egan, RW; Kreutner, W; Siegel, MI1
Grönroos, M; Kauppila, T; Pertovaara, A1
Bochner, F; Capon, DA; Danz, C; Kerry, N; Mikus, G; Somogyi, AA1
Kemppainen, P; Könönen, M; Pertovaara, A; Waltimo, A; Waltimo, T1
Hansson, P; Kinnman, E; Nygårds, EB1
Dahl, JB; Dirks, J; Duedahl, TH; Larsen, NE; Petersen, KB; Romsing, J1
Frymoyer, AR; Petersen, KL; Rowbotham, MC1
Lomas, LM; Picker, MJ; Terner, JM1
Faruqi, S; Morice, AH; Thompson, R; Wright, C1
Brew, J; Caparros-Wanderley, W; Dhar, S; Dicpinigaitis, PV; Gayle, Y; Johnson, A1
Chiang, W; Li, ML; Lin, JH; Liu, YT; Yao, HT1
Fu, JH; Guo, H; Hao, W; Jin, L; Liu, JX; Liu, ZX; Xin, GJ; Xu, SJ; You, Y1

Trials

7 trial(s) available for capsaicin and dextromethorphan

ArticleYear
An attempt to attenuate experimental pain in humans by dextromethorphan, an NMDA receptor antagonist.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Capsaicin; Dextromethorphan; Female; Hot Temperature; Humans; Male; Middle Aged; Pain Measurement; Pain Threshold; Physical Stimulation; Receptors, N-Methyl-D-Aspartate; Spinal Cord

1995
The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:3

    Topics: Adult; Aerosols; Anti-Arrhythmia Agents; Antitussive Agents; Area Under Curve; Capsaicin; Chromatography, High Pressure Liquid; Cough; Cytochrome P-450 CYP2D6; Dextromethorphan; Female; Humans; Male; Matched-Pair Analysis; Polymorphism, Genetic; Quinidine; Reference Values

1996
Effects of dextromethorphan in clinical doses on capsaicin-induced ongoing pain and mechanical hypersensitivity.
    Journal of pain and symptom management, 1997, Volume: 14, Issue:4

    Topics: Adult; Analgesics; Capsaicin; Dextromethorphan; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Humans; Hypersensitivity; Male; Middle Aged; Pain; Stress, Mechanical

1997
Intravenous dextromethorphan to human volunteers: relationship between pharmacokinetics and anti-hyperalgesic effect.
    Pain, 2005, Volume: 113, Issue:3

    Topics: Adolescent; Adult; Area Under Curve; Capsaicin; Cross-Over Studies; Dextromethorphan; Dextrorphan; Double-Blind Method; Excitatory Amino Acid Antagonists; Humans; Hyperalgesia; Infusions, Intravenous; Male; Pain; Pain Measurement; Pain Threshold; Reaction Time; Time Factors; Treatment Outcome

2005
Placebo-controlled comparison of a morphine/dextromethorphan combination with morphine on experimental pain and hyperalgesia in healthy volunteers.
    The journal of pain, 2007, Volume: 8, Issue:1

    Topics: Adult; Analgesics, Opioid; Capsaicin; Dextromethorphan; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Forearm; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Morphine; Pain; Thigh

2007
A randomized placebo controlled trial to evaluate the effects of butamirate and dextromethorphan on capsaicin induced cough in healthy volunteers.
    British journal of clinical pharmacology, 2014, Volume: 78, Issue:6

    Topics: Adult; Capsaicin; Cough; Cross-Over Studies; Dextromethorphan; Female; Healthy Volunteers; Humans; Male; Middle Aged; Phenylbutyrates

2014
Inhibition of cough reflex sensitivity by diphenhydramine during acute viral respiratory tract infection.
    International journal of clinical pharmacy, 2015, Volume: 37, Issue:3

    Topics: Adult; Antitussive Agents; Capsaicin; Cough; Dextromethorphan; Diphenhydramine; Double-Blind Method; Female; Humans; Male; Reflex; Respiratory Tract Infections; Young Adult

2015

Other Studies

9 other study(ies) available for capsaicin and dextromethorphan

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Antitussive effects of Ca2+ channel antagonists.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Animals; Antitussive Agents; Calcium Channel Blockers; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Drug Synergism; Flunarizine; Guinea Pigs; Male; Morphine; Nifedipine; Verapamil

1992
Effects of 8-hydroxy-2-(di-n-propylamino)tetralin, a selective agonist of 5-HT1A receptors, on the cough reflex in rats.
    European journal of pharmacology, 1991, Oct-15, Volume: 203, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Tetrahydronaphthalenes

1991
The effects of morphine and morphine-related compounds on the rate of afferent discharges from the pulmonary receptors in bullfrog.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:3

    Topics: Animals; Apomorphine; Capsaicin; Dextromethorphan; In Vitro Techniques; Levallorphan; Lung; Morphine; Morphine Derivatives; Naloxone; Neurons, Afferent; Pentazocine; Rana catesbeiana; Receptors, Opioid

1985
Antitussive effects of GABAB agonists in the cat and guinea-pig.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Animals; Antitussive Agents; Baclofen; Capsaicin; Cats; Codeine; Cough; Dextromethorphan; Electromyography; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Irritants; Male; Organophosphorus Compounds; Respiratory Muscles

1993
Differential effects of noxious conditioning stimulation of the cheek by capsaicin on human sensory and inhibitory masseter reflex responses evoked by tooth pulp stimulation.
    Journal of dental research, 1997, Volume: 76, Issue:9

    Topics: Administration, Cutaneous; Adult; Bite Force; Capsaicin; Cheek; Dental Pulp; Dextromethorphan; Differential Threshold; Dose-Response Relationship, Drug; Double-Blind Method; Electric Stimulation; Evoked Potentials; Humans; Irritants; Male; Masseter Muscle; Middle Aged; Muscle Contraction; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reflex; Sensation; Skin

1997
Sex differences in NMDA antagonist enhancement of morphine antihyperalgesia in a capsaicin model of persistent pain: comparisons to two models of acute pain.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:2

    Topics: Acute Disease; Analgesics, Opioid; Animals; Capsaicin; Data Interpretation, Statistical; Dextromethorphan; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Hot Temperature; Hyperalgesia; Male; Morphine; N-Methylaspartate; Pain Measurement; Rats; Rats, Inbred F344; Sex Characteristics

2008
Food-Drug Interaction between the Adlay Bran Oil and Drugs in Rats.
    Nutrients, 2019, Oct-15, Volume: 11, Issue:10

    Topics: Administration, Intravenous; Administration, Oral; Animals; Capsaicin; Chlorzoxazone; Cytochrome P-450 Enzyme System; Dextromethorphan; Diclofenac; Diltiazem; Food-Drug Interactions; Intestinal Absorption; Intestines; Liver; Male; Plant Oils; Rats, Sprague-Dawley; Risk Assessment; Theophylline

2019
[Effect of Jinzhen Oral Liquid on cough after lipopolysaccharide-induced infection in rats and mechanism].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:17

    Topics: Animals; Capsaicin; Cough; Dextromethorphan; Eosine Yellowish-(YS); Hematoxylin; Lipopolysaccharides; Male; Medicine, Chinese Traditional; Nerve Growth Factor; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptor, trkA; RNA, Messenger; Tropomyosin; TRPV Cation Channels; Water

2022