capsaicin and cinnamaldehyde

capsaicin has been researched along with cinnamaldehyde in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.92)18.2507
2000's14 (26.92)29.6817
2010's30 (57.69)24.3611
2020's7 (13.46)2.80

Authors

AuthorsStudies
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Nilius, B; Owsianik, G; Talavera, K; Voets, T1
Horie, S; Takayama, H; Terada, Y; Tominaga, M; Uchida, K; Watanabe, T1
Doble, M; Manju, SL; Sinha, S1
Ann, J; Blumberg, PM; Choi, K; Esch, TE; Ha, HJ; Hwang, SW; Kim, H; Kim, HS; Kim, M; Kim, YH; Lee, J; Pearce, LV; Thorat, SA; Turcios, NA1
Azizan, A; Blevins, RD1
Prescott, J; Swain-Campbell, N1
Carstens, E; Mitsuyo, T1
Andrade, EL; André, E; Calixto, JB; Ferreira, J1
Alqatari, M; Ernfors, P; Hjerling-Leffler, J; Koltzenburg, M1
Albin, KC; Carstens, E; Carstens, MI1
Araki, I; Du, S; Nomura, T; Takeda, M; Yoshiyama, M1
Andersson, KE; Gratzke, C; Hedlund, P; Sigl, K; Stief, C; Streng, T; Waldkirch, E1
Iwasaki, Y; Kobata, K; Tanabe, M; Watanabe, T1
Alenmyr, L; Greiff, L; Högestätt, ED; Zygmunt, PM1
Naidu, KA; Raghavendra, RH1
Babes, A; Barbu, I; Ciobanu, C; Kerek, F; Neacsu, C; Szegli, G; Toader, O1
Andrè, E; Baraldi, PG; Gatti, R; Geppetti, P; Patacchini, R; Preti, D; Trevisani, M1
Cahusac, PM1
Andersson, KE; Gratzke, C; Hedlund, P; Stief, C; Streng, T; Weinhold, P1
Du, XL; Guo, JY; Guo, SY; Huo, HR; Jiang, TL; Li, LF; Lin, N; Liu, HB; Sui, F; Yang, N; Zhang, CB; Zhao, BS1
Furue, H; Imoto, K; Katafuchi, T; Mizuguchi-Takase, H; Pickering, AE; Rashid, MH; Uta, D; Yoshimura, M1
Carstens, E; Carstens, MI; Cheung, S; Furrer, S; Ivanov, MA; Klein, AH; Sawyer, CM; Simons, CT; Slack, JP; Zanotto, KL1
Andrade, EL; Bento, AF; Calixto, JB; Dias, MA; Forner, S; Koepp, J; Leal, PC; Leite, DF1
About, I; Curtis, TM; El Karim, IA; Irwin, CR; Killough, SA; Linden, GJ; Lundy, FT; McGahon, MK1
André, E; Cabrini, DA; da Silveira Prudente, A; Dalmolin, GD; Ferreira, J; Guerra, GP; Oliveira, SM; Otuki, MF; Rossato, MF; Silva, CR1
Anand, P; Roberts, K; Shenoy, R1
Dong, L; Li, Q; Luo, P; Rong, W; Sun, B; Zhou, Y1
Alenmyr, L; Greiff, L; Herrmann, A; Högestätt, ED; Zygmunt, PM1
Baggio, CH; Freitas, CS; Iacomini, M; Marcon, R; Marques, MC; Rae, GA; Santos, AR; Sassaki, GL; Smiderle, FR; Werner, MF1
Ebihara, S; Ebihara, T; Gui, P; Kanezaki, M; Kohzuki, M1
Furukawa, Y; Jinno, H; Ohkawara, S; Tanaka-Kagawa, T1
Córdova, MM; Montrucchio, DP; Santos, AR1
Horii, A; Imai, T; Inohara, H; Ishida, Y; Kamakura, T; Kitahara, T; Nakamura, Y; Okazaki, S; Shimada, S; Takimoto, Y; Uno, A; Yamada, T1
Baggio, CH; Cipriani, TR; da Silva, CF; de Souza, LM; Hamm, LA; Nascimento, AM; Nomura, EC; Rodrigues, MR; Werner, MF1
Alpizar, YA; Radwan, A; Radwan, I; Sanchez, A; Talavera, K; Voets, T1
Carstens, E; Carstens, MI; Davoodi, A; Joe, CL; Klein, AH; Takechi, K1
Di Silvio, L; Duggal, AK; Egbuniwe, O; Grant, AD; Grover, S; Mavroudis, A; Renton, T; Yazdi, M1
Terada, Y; Watanabe, T1
Beaumont, M; Camacho, S; le Coutre, J; Ledda, M; Merlini, JM; Michlig, S; Mukherjee, R; Tavenard, A1
Buntinx, L; Cornelissen, E; de Hoon, J; Janssen, M; Levtchenko, E; Morlion, B; Vangeel, L; Voets, T; Vriens, J1
Gratzke, C; Hedlund, P; Hennenberg, M; Stief, CG; Strittmatter, F; Weinhold, P1
Carpenter, GH; Hans, J; Houghton, JW; Ley, JP; Pesaro, M; Proctor, G1
Barbosa, TM; Barroso, LKV; Batista, FLA; Campos, AR; da Silva, ARA; Damasceno, MBMV; de Melo, JMA; de Oliveira, BA; Guedes, MIF; Holanda, DKR; Lima, MDCL; Magalhães, FEA; Moura, LFWG; Nogueira, AB; Santos, SAAR; Serpa, OF1
Lötsch, J; Weyer-Menkhoff, I1
Bartho, L; Bencsik, T; Dekany, A; Sandor, ZI1
Binda, NS; Borges, MH; Carobin, NV; Castro Junior, CJ; Ferreira, J; Gomez, MV; Kushmerick, C; Pinto Nagem, RA; Ribeiro, FM; Rita Pereira, EM; Santos, DC; Silva Júnior, CA; Silva, JF; Souza, JM1
Bamps, D; Buntinx, L; de Hoon, J; Macours, L1
Buday, T; Grendar, M; Plevkova, J; Sterusky, M1
Bhadada, SK; Bhunia, RK; Bishnoi, M; Kaur, J; Khare, P; Kondepudi, KK; Kuhad, A; Kumar, V; Mahajan, N; Shafi, S1
Alvarez-Berdugo, D; Clavé, P; Ortega, O; Rofes, L; Tomsen, N1
Bhunia, RK; Bishnoi, M; Kaur, J; Kaur, S; Kondepudi, KK; Kuhad, A; Kumar, V; Singh, DP1

Reviews

2 review(s) available for capsaicin and cinnamaldehyde

ArticleYear
Sensing with TRP channels.
    Nature chemical biology, 2005, Volume: 1, Issue:2

    Topics: Animals; Humans; Ligands; Models, Biological; Phylogeny; Temperature; Transient Receptor Potential Channels

2005
5-Lipoxygenase as a drug target: A review on trends in inhibitors structural design, SAR and mechanism based approach.
    Bioorganic & medicinal chemistry, 2019, 09-01, Volume: 27, Issue:17

    Topics: Animals; Arachidonate 5-Lipoxygenase; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Molecular Structure; Structure-Activity Relationship

2019

Trials

5 trial(s) available for capsaicin and cinnamaldehyde

ArticleYear
Modulation of oral heat and cold pain by irritant chemicals.
    Chemical senses, 2008, Volume: 33, Issue:1

    Topics: Acrolein; Adolescent; Adult; Capsaicin; Cold Temperature; Female; Hot Temperature; Humans; Irritants; Male; Menthol; Middle Aged; Mustard Plant; Nociceptors; Plant Oils; Temperature; Thermosensing; Tongue; Transient Receptor Potential Channels

2008
TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.
    Clinical physiology and functional imaging, 2011, Volume: 31, Issue:6

    Topics: Acrolein; Administration, Intranasal; Adult; Aged; Arachidonic Acids; Biopsy; Calcium; Calcium Channels; Capsaicin; Cilia; Cross-Over Studies; Double-Blind Method; Endocannabinoids; Humans; Immunohistochemistry; Methanol; Middle Aged; Movement; Mucin 5AC; Mucin-5B; Mustard Plant; Nasal Lavage; Nasal Mucosa; Nerve Tissue Proteins; Pain; Pain Measurement; Plant Oils; Polyunsaturated Alkamides; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sensory System Agents; Sweden; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult

2011
Effect of cigarette smoking on cough reflex induced by TRPV1 and TRPA1 stimulations.
    Respiratory medicine, 2012, Volume: 106, Issue:3

    Topics: Acrolein; Adolescent; Adult; Calcium Channels; Capsaicin; Cough; Cross-Over Studies; Humans; Male; Nerve Tissue Proteins; Reflex; Sensory Thresholds; Smoking; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Young Adult

2012
Effects of TRP channel agonist ingestion on metabolism and autonomic nervous system in a randomized clinical trial of healthy subjects.
    Scientific reports, 2016, Feb-17, Volume: 6

    Topics: Acrolein; Adult; Autonomic Nervous System; Blood Pressure; Calcium Channels; Capsaicin; Cross-Over Studies; Energy Metabolism; Flavoring Agents; Healthy Volunteers; Heart Rate; Humans; Nerve Tissue Proteins; Oxidation-Reduction; Signal Transduction; Thermography; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult

2016
TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers.
    The Clinical journal of pain, 2019, Volume: 35, Issue:4

    Topics: Acrolein; Adult; Capsaicin; Cold Temperature; Cross-Over Studies; Female; Healthy Volunteers; Hot Temperature; Humans; Hyperalgesia; Male; Menthol; Neuralgia; Pain Threshold; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult

2019

Other Studies

45 other study(ies) available for capsaicin and cinnamaldehyde

ArticleYear
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.
    Journal of natural products, 2014, Feb-28, Volume: 77, Issue:2

    Topics: Africa; Alkaloids; Calcium; Capsaicin; Humans; Ibogaine; Menthol; Molecular Structure; Plant Bark; Pyrimidinones; Transient Receptor Potential Channels; Trees; TRPV Cation Channels; Voacanga

2014
Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic.
    Journal of medicinal chemistry, 2020, 01-09, Volume: 63, Issue:1

    Topics: Analgesics; Animals; Capsaicin; CHO Cells; Cricetulus; Drug Discovery; Hyperalgesia; Mice, Inbred ICR; Neuralgia; Phenylurea Compounds; Swine; Thiazoles; TRPV Cation Channels

2020
Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay.
    Archives of environmental contamination and toxicology, 1995, Volume: 28, Issue:2

    Topics: Acrolein; Antimutagenic Agents; Camphanes; Capsaicin; Eugenol; Flavoring Agents; Food Preservatives; Isothiocyanates; Mutagenesis; Mutagenicity Tests; Spices; Thymol

1995
Responses to repeated oral irritation by capsaicin, cinnamaldehyde and ethanol in PROP tasters and non-tasters.
    Chemical senses, 2000, Volume: 25, Issue:3

    Topics: Acrolein; Administration, Oral; Adolescent; Adult; Capsaicin; Ethanol; Female; Humans; Irritants; Male; Taste; Taste Threshold

2000
Neural correlates of oral irritation by mustard oil and other pungent chemicals: a hot topic.
    Chemical senses, 2005, Volume: 30 Suppl 1

    Topics: Acrolein; Animals; Capsaicin; Cold Temperature; Hot Temperature; Models, Biological; Models, Neurological; Mustard Plant; Neurons; Plant Oils; Rats; Temperature; Time Factors; Tongue; Transient Receptor Potential Channels

2005
Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder.
    Biochemical pharmacology, 2006, Jun-28, Volume: 72, Issue:1

    Topics: Acrolein; Anilides; Animals; Ankyrins; Binding Sites; Calcium Channels; Capsaicin; Cinnamates; Diterpenes; Dose-Response Relationship, Drug; Drug Antagonism; In Vitro Techniques; Isothiocyanates; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Ruthenium Red; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels; Urinary Bladder

2006
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Mar-07, Volume: 27, Issue:10

    Topics: Acrolein; Aging; Animals; Animals, Newborn; Calcium Channels; Capsaicin; Cell Differentiation; Cell Lineage; Cells, Cultured; Cold Temperature; Embryo, Mammalian; Embryonic Development; Ganglia, Spinal; Menthol; Mice; Mice, Inbred C57BL; Neurons, Afferent; Nociceptors; Plant Lectins; RNA, Messenger; Thermoreceptors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2007
Transient receptor potential channel A1 involved in sensory transduction of rat urinary bladder through C-fiber pathway.
    Urology, 2007, Volume: 70, Issue:4

    Topics: Acrolein; Afferent Pathways; Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Female; Ganglia, Spinal; Isothiocyanates; Nerve Fibers, Unmyelinated; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensation; Sensory System Agents; TRPA1 Cation Channel; TRPC Cation Channels; Urinary Bladder; Urodynamics

2007
Transient receptor potential A1 (TRPA1) activity in the human urethra--evidence for a functional role for TRPA1 in the outflow region.
    European urology, 2009, Volume: 55, Issue:3

    Topics: Acrolein; Capsaicin; Female; Humans; In Vitro Techniques; Isothiocyanates; Male; Middle Aged; Sensory System Agents; Sulfides; TRPC Cation Channels; Urethra

2009
TRPA1 agonists--allyl isothiocyanate and cinnamaldehyde--induce adrenaline secretion.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:10

    Topics: Acrolein; Adrenal Glands; Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Cholinergic Antagonists; Epinephrine; Isothiocyanates; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; TRPA1 Cation Channel; TRPC Cation Channels

2008
TRPV1-mediated itch in seasonal allergic rhinitis.
    Allergy, 2009, Volume: 64, Issue:5

    Topics: Acrolein; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Arachidonic Acids; Calcium Channel Blockers; Calcium Channels; Capsaicin; Endocannabinoids; Humans; Menthol; Mustard Plant; Nasal Provocation Tests; Nerve Tissue Proteins; Plant Oils; Polyunsaturated Alkamides; Pruritus; Rhinitis, Allergic, Seasonal; Sensory System Agents; Severity of Illness Index; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2009
Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis.
    Prostaglandins, leukotrienes, and essential fatty acids, 2009, Volume: 81, Issue:1

    Topics: Acrolein; Adenosine Diphosphate; Alkaloids; Allyl Compounds; Arachidonic Acid; Benzodioxoles; Calcimycin; Capsaicin; Collagen Type III; Curcumin; Eugenol; Humans; Malondialdehyde; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyunsaturated Alkamides; Quercetin; Spices; Sulfides; Thromboxanes

2009
Substance MCS-18 isolated from Helleborus purpurascens is a potent antagonist of the capsaicin receptor, TRPV1, in rat cultured sensory neurons.
    Physiological research, 2010, Volume: 59, Issue:2

    Topics: Acids; Acrolein; Animals; Biological Products; Calcium; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Helleborus; Hot Temperature; Membrane Potentials; Pain; Patch-Clamp Techniques; Rats; Sensory Receptor Cells; TRPV Cation Channels

2010
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents.
    British journal of pharmacology, 2009, Volume: 158, Issue:6

    Topics: Acrolein; Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Drug Delivery Systems; Guinea Pigs; Isothiocyanates; Male; Oxidative Stress; Smoke; Transient Receptor Potential Channels

2009
Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.
    Journal of the peripheral nervous system : JPNS, 2009, Volume: 14, Issue:4

    Topics: Acrolein; Action Potentials; Animals; Ankyrins; Calcium Channels; Camphor; Capsaicin; Evoked Potentials; Hair Follicle; In Vitro Techniques; Isothiocyanates; Male; Mechanoreceptors; Menthol; Physical Stimulation; Pyrimidinones; Rats; Rats, Wistar; Ruthenium Red; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels

2009
TRPA1 receptor induced relaxation of the human urethra involves TRPV1 and cannabinoid receptor mediated signals, and cyclooxygenase activation.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Acrolein; Analysis of Variance; Arginine; Calcium Channels; Capsaicin; Cyclohexanols; Female; Humans; Immunohistochemistry; Indomethacin; Isothiocyanates; Male; Middle Aged; Nerve Tissue Proteins; Receptors, Cannabinoid; Signal Transduction; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Urethra

2010
Cinnamaldehyde up-regulates the mRNA expression level of TRPV1 receptor potential ion channel protein and its function in primary rat DRG neurons in vitro.
    Journal of Asian natural products research, 2010, Volume: 12, Issue:1

    Topics: Acrolein; Animals; Animals, Newborn; Capsaicin; Cassia; Ion Channels; Neurons; Plant Stems; Rats; Rats, Sprague-Dawley; RNA, Messenger; TRPM Cation Channels; TRPV Cation Channels

2010
TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord.
    The European journal of neuroscience, 2010, Volume: 31, Issue:11

    Topics: Acrolein; Action Potentials; Animals; Ankyrins; Antimutagenic Agents; Calcium Channels; Capsaicin; Cell Shape; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Food Preservatives; Inhibitory Postsynaptic Potentials; Isothiocyanates; Male; Nerve Fibers, Unmyelinated; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sensory System Agents; Spinal Cord; Substantia Gelatinosa; Synapses; Synaptic Transmission; TRPA1 Cation Channel; TRPC Cation Channels

2010
A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats.
    Journal of neurophysiology, 2011, Volume: 105, Issue:4

    Topics: Acrolein; Amides; Animals; Antipruritics; Behavior, Animal; Calcium; Capsaicin; Cells, Cultured; Ganglia, Spinal; Humans; Male; Menthol; Models, Animal; Plant Extracts; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Zanthoxylum

2011
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
    American journal of physiology. Renal physiology, 2011, Volume: 300, Issue:5

    Topics: Acetanilides; Acrolein; Animals; Ankyrins; Calcium Channels; Capsaicin; Carbachol; Disease Models, Animal; Ganglia, Spinal; Muscle Contraction; Oligonucleotides, Antisense; Purines; Rats; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urodynamics

2011
Human dental pulp fibroblasts express the "cold-sensing" transient receptor potential channels TRPA1 and TRPM8.
    Journal of endodontics, 2011, Volume: 37, Issue:4

    Topics: Acetanilides; Acrolein; Adult; Blotting, Western; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Capsaicin; Cells, Cultured; Cold Temperature; Cytophotometry; Dental Pulp; Fibroblasts; Humans; Immunohistochemistry; Membrane Proteins; Menthol; Nerve Tissue Proteins; Nociceptors; Physical Stimulation; Purines; Reverse Transcriptase Polymerase Chain Reaction; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; Young Adult

2011
The involvement of TRPA1 channel activation in the inflammatory response evoked by topical application of cinnamaldehyde to mice.
    Life sciences, 2011, Jun-20, Volume: 88, Issue:25-26

    Topics: Acrolein; Administration, Topical; Animals; Blotting, Western; Capsaicin; Dermatitis, Contact; Edema; Male; Mice; Peroxidase; Skin; Transient Receptor Potential Channels; TRPA1 Cation Channel

2011
A novel human volunteer pain model using contact heat evoked potentials (CHEP) following topical skin application of transient receptor potential agonists capsaicin, menthol and cinnamaldehyde.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:7

    Topics: Acrolein; Adult; Capsaicin; Electroencephalography; Evoked Potentials; Female; Hot Temperature; Human Experimentation; Humans; Male; Menthol; Middle Aged; Models, Biological; Pain; Pain Measurement; Pain Threshold; Sensory System Agents; Skin; Transient Receptor Potential Channels; Young Adult

2011
Sensitivity of bronchopulmonary receptors to cold and heat mediated by transient receptor potential cation channel subtypes in an ex vivo rat lung preparation.
    Respiratory physiology & neurobiology, 2011, Aug-15, Volume: 177, Issue:3

    Topics: Acetanilides; Acrolein; Animals; Capsaicin; Cold Temperature; Hot Temperature; In Vitro Techniques; Lung; Male; Menthol; Purines; Rats; Rats, Sprague-Dawley; Respiratory System; Sensory System Agents; TRPM Cation Channels

2011
Antinociception of β-D-glucan from Pleurotus pulmonarius is possibly related to protein kinase C inhibition.
    International journal of biological macromolecules, 2012, Apr-01, Volume: 50, Issue:3

    Topics: Acid Sensing Ion Channels; Acrolein; Analgesics; Animals; Capsaicin; Enzyme Activation; Glucans; Male; Menthol; Mice; Nerve Tissue Proteins; Nociception; Pleurotus; Protein Kinase C; Protein Kinase Inhibitors; Sodium Channels; Tetradecanoylphorbol Acetate; TRPV Cation Channels

2012
Methylglyoxal activates the human transient receptor potential ankyrin 1 channel.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:4

    Topics: Acrolein; Calcium; Calcium Channels; Capsaicin; Cloning, Molecular; Diabetic Neuropathies; HEK293 Cells; Humans; Nerve Tissue Proteins; Pyruvaldehyde; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2012
Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetone; Acrolein; Acrylamides; Acute Disease; Alkaloids; Analgesics; Animals; Aporphines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Pain; Cold Temperature; Freund's Adjuvant; Gene Expression; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Transient Receptor Potential Channels; TRPA1 Cation Channel

2013
Functional expression of TRPV1 and TRPA1 in rat vestibular ganglia.
    Neuroscience letters, 2013, Sep-27, Volume: 552

    Topics: Acetanilides; Acrolein; Animals; Calcium; Capsaicin; Molecular Imaging; Primary Cell Culture; Purines; Rats; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels; Vestibular Nerve

2013
Antinociceptive effects of ethanolic extract from the flowers of Acmella oleracea (L.) R.K. Jansen in mice.
    Journal of ethnopharmacology, 2013, Nov-25, Volume: 150, Issue:2

    Topics: Acrolein; Analgesics; Animals; Asteraceae; Capsaicin; Ethanol; Flowers; Formaldehyde; Hot Temperature; Hyperalgesia; Ligation; Male; Mice; Pain; Phytotherapy; Plant Extracts; Sciatic Nerve; Solvents; Touch

2013
Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca(2+) imaging experiments.
    Cell calcium, 2013, Volume: 54, Issue:5

    Topics: Acrolein; Animals; Calcium; Calcium Signaling; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Flow Cytometry; Fura-2; HEK293 Cells; Humans; Leucine; Menthol; Pregnenolone; Sulfonamides; Transfection; TRPV Cation Channels

2013
Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses.
    Neuroscience, 2014, Jun-20, Volume: 271

    Topics: Acrolein; Action Potentials; Animals; Capsaicin; Cold Temperature; Cymenes; Dose-Response Relationship, Drug; Eugenol; Hot Temperature; Male; Menthol; Monoterpenes; Mustard Plant; Neurons; Neurons, Afferent; Nociceptive Pain; Plant Oils; Rats, Sprague-Dawley; Sensory System Agents; Thermosensing; Tongue; Trigeminal Ganglion; TRPV Cation Channels

2014
TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release.
    Journal of dental research, 2014, Volume: 93, Issue:9

    Topics: Acetanilides; Acrolein; Adenosine Triphosphate; Calcium Channels; Calcium Signaling; Capsaicin; Cell Culture Techniques; Cell Line; Culture Media, Conditioned; Dental Pulp; Humans; Isothiocyanates; Leucine; Nerve Tissue Proteins; Nociceptors; Odontoblasts; Purines; Pyrimidinones; Sensory System Agents; Sulfonamides; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2014
Food Compounds Activating Thermosensitive TRP Channels in Asian Herbal and Medicinal Foods.
    Journal of nutritional science and vitaminology, 2015, Volume: 61 Suppl

    Topics: Acrolein; Animals; Capsaicin; Ion Channels; Mice; Mitochondrial Proteins; Plants, Medicinal; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Uncoupling Protein 1; Zanthoxylum; Zingiberaceae

2015
TRPV1 dysfunction in cystinosis patients harboring the homozygous 57 kb deletion.
    Scientific reports, 2016, 10-13, Volume: 6

    Topics: Acrolein; Adolescent; Adult; Alleles; Capsaicin; Codon; Cystinosis; Europe; Female; Gene Deletion; Homozygote; Hot Temperature; Humans; Lysosomes; Male; Mutation; Sequence Deletion; TRPA1 Cation Channel; TRPV Cation Channels; Young Adult

2016
Transient receptor potential a1 (TRPA1) agonists inhibit contractions of the isolated human ureter.
    Neurourology and urodynamics, 2018, Volume: 37, Issue:2

    Topics: Acrolein; Aged; Calcitonin Gene-Related Peptide; Capsaicin; Female; Humans; Hydrogen Sulfide; Isothiocyanates; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Synaptic Transmission; TRPA1 Cation Channel; TRPV Cation Channels; Tyrosine 3-Monooxygenase; Ureter; Vimentin

2018
Sensory effects of transient receptor potential channel agonists on whole mouth saliva extensional rheology.
    Journal of texture studies, 2017, Volume: 48, Issue:4

    Topics: Acrolein; Adult; Capsaicin; Female; Flavoring Agents; Healthy Volunteers; Humans; Male; Menthol; Mouth; Mouthwashes; Rheology; Saliva; Sensory System Agents; Transient Receptor Potential Channels; Young Adult

2017
Orofacial antinociceptive effect of Mimosa tenuiflora (Willd.) Poiret.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Acrolein; Analgesics; Animals; Antioxidants; Capsaicin; Chemical Fractionation; Chlorocebus aethiops; Ethanol; Facial Pain; Glutamic Acid; Glyburide; Mice; Mimosa; Motor Activity; Naloxone; NG-Nitroarginine Methyl Ester; Nociception; Phenols; Plant Extracts; Rats, Wistar; Temporomandibular Joint; Vero Cells

2018
Effects of Cinnamaldehyde on Smooth Muscle Preparations.
    Pharmacology, 2019, Volume: 104, Issue:3-4

    Topics: Acrolein; Animals; Capsaicin; Female; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; TRPV Cation Channels; Urinary Bladder

2019
Phoneutria toxin PnTx3-5 inhibits TRPV1 channel with antinociceptive action in an orofacial pain model.
    Neuropharmacology, 2020, 01-01, Volume: 162

    Topics: Acrolein; Anilides; Animals; Calcium; Calcium Signaling; Capsaicin; Cinnamates; Disease Models, Animal; Facial Pain; Glutamic Acid; HEK293 Cells; Humans; Inhibitory Concentration 50; Male; Neuropeptides; Nociception; Patch-Clamp Techniques; Rats; Sensory System Agents; Transfection; Trigeminal Ganglion; TRPA1 Cation Channel; TRPV Cation Channels

2020
Laser speckle contrast imaging, the future DBF imaging technique for TRP target engagement biomarker assays.
    Microvascular research, 2020, Volume: 129

    Topics: Acrolein; Adolescent; Adult; Biomarkers; Blood Flow Velocity; Capsaicin; Forearm; Healthy Volunteers; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Perfusion Imaging; Predictive Value of Tests; Regional Blood Flow; Reproducibility of Results; Sensory System Agents; Skin; Time Factors; TRPA1 Cation Channel; TRPV Cation Channels; Young Adult

2020
Female Guinea Pig Model for Cough Studies and Its Response to Most Common Tussive Substances.
    Physiological research, 2020, 03-27, Volume: 69, Issue:Suppl 1

    Topics: Acrolein; Animals; Capsaicin; Citric Acid; Cough; Disease Models, Animal; Female; Guinea Pigs; Male; Sex Characteristics

2020
Combination of TRP channel dietary agonists induces energy expending and glucose utilizing phenotype in HFD-fed mice.
    International journal of obesity (2005), 2022, Volume: 46, Issue:1

    Topics: Acrolein; Animals; Capsaicin; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Menthol; Mice; Mice, Inbred C57BL; Phenotype; Transient Receptor Potential Channels

2022
A Comparative Study on the Effect of Acute Pharyngeal Stimulation with TRP Agonists on the Biomechanics and Neurophysiology of Swallow Response in Patients with Oropharyngeal Dysphagia.
    International journal of molecular sciences, 2022, Sep-15, Volume: 23, Issue:18

    Topics: Acrolein; Acyclic Monoterpenes; Alkaloids; Benzodioxoles; Biomechanical Phenomena; Capsaicin; Deglutition; Deglutition Disorders; Humans; Menthol; Piperidines; Polyunsaturated Alkamides; Retrospective Studies; Zinc

2022
Transient Receptor Potential (TRP) based polypharmacological combination stimulates energy expending phenotype to reverse HFD-induced obesity in mice.
    Life sciences, 2023, Jul-01, Volume: 324

    Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Capsaicin; Diet, High-Fat; Energy Metabolism; Menthol; Mice; Mice, Inbred C57BL; Obesity; Phenotype; Quality of Life

2023