capsaicin has been researched along with anandamide in 198 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (3.03) | 18.2507 |
| 2000's | 153 (77.27) | 29.6817 |
| 2010's | 35 (17.68) | 24.3611 |
| 2020's | 4 (2.02) | 2.80 |
| Authors | Studies |
|---|---|
| Nilius, B; Owsianik, G; Talavera, K; Voets, T | 1 |
| Allarà, M; Appendino, G; Cascio, MG; De Petrocellis, L; Di Marzo, V; Ligresti, A; Minassi, A; Pertwee, RG; Taglialatela-Scafati, O | 1 |
| Hargreaves, KM; Kilo, S; Richardson, JD | 1 |
| Aanonsen, L; Hargreaves, KM; Richardson, JD | 1 |
| Bisogno, T; Brockie, H; De Petrocellis, L; Di Marzo, V; Melck, D; Pertwee, R; Ross, R; Stevenson, L | 1 |
| Beltramo, M; Piomelli, D | 1 |
| Andersson, DA; Chuang, H; Di Marzo, V; Högestätt, ED; Julius, D; Petersson, J; Sørgård, M; Zygmunt, PM | 1 |
| Bifulco, M; Bisogno, T; Chuang, H; De Petrocellis, L; Di Marzo, V; Julius, D; Melck, D | 1 |
| Chambers, JK; Davis, JB; Gray, J; Gunthorpe, MJ; Jerman, JC; Muir, AI; Nasir, S; Randall, AD; Smart, D | 1 |
| Jerman, JC; Smart, D | 1 |
| Atkinson, K; Bingham, S; Clapham, C; Davey, PT; Davis, JB; Grau, E; Gray, J; Gunthorpe, MJ; Harper, AJ; Harries, MH; Hatcher, JP; Hughes, SA; Latcham, J; Overend, P; Pugh, PL; Rance, K; Randall, A; Rogers, DC; Sheardown, SA | 1 |
| Chuang, H; Högestätt, ED; Julius, D; Movahed, P; Zygmunt, PM | 1 |
| Balla, Z; Csernoch, L; Czéh, G; Szöke, E; Szolcsányi, J | 1 |
| Di Marzo, V; Szallasi, A | 1 |
| Davidge, ST; Fernandez-Patron, C; Koivunen, E; Radomski, MW; Stewart, KG; Zhang, Y | 1 |
| Bisogno, T; Davis, JB; De Petrocellis, L; Di Marzo, V; Pertwee, RG | 1 |
| Bisogno, T; Breivogel, C; Di Marzo, V; Martin, BR; Melck, D; Patrick, G; Razdan, RK; Szallasi, A; Tao, Q | 1 |
| Calignano, A; Désarnaud, F; Freund, TF; Giuffrida, A; Kátona, I; La Rana, G; Mackie, K; Piomelli, D | 1 |
| Chessell, IP; Gauldie, SD; McQueen, DS; Pertwee, R | 1 |
| Brockie, HC; Craib, SJ; Di Marzo, V; Gibson, TM; Leslie, M; Pashmi, G; Pertwee, RG; Ross, RA | 1 |
| Amadesi, S; Bianchi, A; Carreras, M; Creminon, C; Geppetti, P; Harrison, S; Matera, M; Tognetto, M; Trevisani, M | 1 |
| Van de Voorde, J; Vanheel, B | 1 |
| Bisogno, T; Brandi, I; Dasse, O; Davis, JB; De Petrocellis, L; Di Marzo, V; Jefferson, RG; Mahadevan, A; Martin, BR; Razdan, RK; Winckler, RL | 1 |
| Kagaya, M; Page, CP; Spina, D; Tucker, RC | 1 |
| Capasso, F; Capasso, R; Di Carlo, G; Izzo, AA; Mascolo, N; Pinto, L | 1 |
| Bisogno, T; Davis, JB; De Petrocellis, L; Di Marzo, V; Finazzi-Agro, A; Maccarrone, M | 1 |
| Brough, SJ; Cairns, W; Davis, JB; Gunthorpe, MJ; Hayes, PD; Jerman, JC; Randall, AD; Ranson, J; Smart, D | 1 |
| Bisogno, T; Davis, JB; De Petrocellis, L; Di Marzo, V; Fernandez-Ruiz, JJ; Lastres-Becker, I; Milone, A | 1 |
| Bisogno, T; De Petrocellis, L; Di Marzo, V | 1 |
| Morisset, V; Urban, L | 1 |
| Harrison, C; Lambert, DG; Rowbotham, DJ; Smart, D; Sprague, J | 1 |
| Järvinen, K; Järvinen, T; Laine, K; Laitinen, JT; Pate, DW; Savinainen, J | 1 |
| Gitlin, JM; Mitchell, JA; Stanford, SJ | 1 |
| Davis, JB; Mapplebeck, S; McNaughton, PA; Moriondo, A; Vellani, V | 1 |
| Bifulco, M; Bisogno, T; De Petrocellis, L; Di Marzo, V; Melck, D; Orlando, P; Vogel, Z; Zagoory, O | 1 |
| Craib, SJ; Ellington, HC; Pertwee, RG; Ross, RA | 1 |
| Erbelding, D; Kilbinger, H; Mang, CF | 1 |
| Adler-Graschinsky, E; Mendizábal, VE; Orliac, ML | 1 |
| McQueen, DS; Smith, PJ | 1 |
| Davis, JB; De Petrocellis, L; Di Marzo, V | 1 |
| Bisogno, T; Brandi, I; Davis, JB; De Petrocellis, L; Di Marzo, V; Hanus, L; Mechoulam, R; Moriello, AS; Ponde, DE; Tchilibon, S | 1 |
| Bottrill, FE; Ford, WR; Hiley, CR; Ho, WS; White, R | 1 |
| Jerman, JC; Kendall, DA; Middlemiss, DN; Ralevic, V; Smart, D | 1 |
| Boachie-Ansah, G; Grainger, J | 1 |
| Al-Hayani, A; Davies, SN; Pertwee, RG; Ross, RA; Wease, KN | 1 |
| Göthert, M; Kwolek, G; Malinowska, B | 1 |
| Lever, IJ; Malcangio, M | 1 |
| Bisogno, T; Brandi, I; De Petrocellis, L; Di Marzo, V; Grier, MC; Griffin, G; Kulasegram, S; Mahadevan, A; Martin, BR; Razdan, RK; Williams, W | 1 |
| Chen, J; Furue, H; Kumamoto, E; Luo, C; Yoshimura, M | 1 |
| Harris, D; Kendall, DA; McCulloch, AI; Randall, MD | 1 |
| Lee, LY; Lin, YS | 1 |
| Chapnick, BM; Howlett, AC; Mukhopadhyay, S | 1 |
| Fowler, CJ; Jonsson, KO; Lambert, DM; Smart, D; Vandevoorde, S | 2 |
| Szallasi, A | 1 |
| Adner, M; Andersson, DA; Högestätt, ED; Zygmunt, PM | 1 |
| Kagaya, M; Lamb, J; Page, CP; Robbins, J; Spina, D | 1 |
| Horie, S; Murayama, T; Someya, A | 1 |
| Barthó, L; Benkó, R; Horváth, OP; Illényi, L; Lázár, Z | 1 |
| Egan, RW; Hey, JA; Jia, Y; McLeod, RL; Parra, LE; Wang, X | 1 |
| Bilbao, A; Cippitelli, A; Del Arco, I; Ferrer, B; Gómez, R; Nava, F; Navarro, M; Piomelli, D; Rodríguez de Fonseca, F; Trigo, JM | 1 |
| Brough, SJ; Davis, JB; Gray, J; Jerman, JC; Ooi, L; Owen, D; Smart, D | 1 |
| Adler-Graschinsky, E; Celuch, SM; Orliac, ML; Peroni, R | 1 |
| Schelegle, ES | 1 |
| Chung, E; Gu, Q; Ho, CY; Lee, LY; Shuei Lin, Y | 1 |
| Helyes, Z; Jakab, B; Németh, J; Pintér, E; Szolcsányi, J; Thán, M | 1 |
| Ahluwalia, J; Bevan, S; Nagy, I; Urban, L; Yaqoob, M | 1 |
| Christie, MJ; Jennings, EA; Roberts, LA; Vaughan, CW | 1 |
| Chiang, HT; Lo, YK; Wu, SN | 1 |
| Appendino, G; Bisogno, T; Chu, CJ; Daddario, N; De Petrocellis, L; Di Marzo, V; Ewing, SA; Huang, SM; Miller, JD; Walker, JM; Zipkin, RE | 1 |
| Schilling, WP; Sinkins, WG; Wisnoskey, BJ | 1 |
| Kaminski, NE; Li, J; Wang, DH | 1 |
| Abumrad, NA; Deutsch, DG; Fatade, F; Glaser, ST; Kaczocha, M; Studholme, KM | 1 |
| Bernardi, G; Berretta, N; Di Marzo, V; Maccarrone, M; Marinelli, S; Matias, I; Mercuri, NB | 1 |
| Bisogno, T; De Petrocellis, L; Di Marzo, V; Hermann, H; Lutz, B; Schiano Moriello, A | 1 |
| Blumberg, PM; Kedei, N; Tóth, A; Wang, Y | 1 |
| Ahern, GP | 1 |
| Bär, PR; Di Marzo, V; Fezza, F; Maccarrone, M; Nicolay, K; van der Stelt, M; van Zadelhoff, G; Veldhuis, WB; Veldink, GA; Vliegenthart, JF; Wadman, MW | 1 |
| Ahluwalia, J; Bevan, S; Nagy, I; Urban, L | 1 |
| Adler-Graschinsky, E; Celuch, SM; del Carmen García, M | 1 |
| Farquhar-Smith, WP; Rice, AS | 1 |
| Dougalis, A; Lees, G | 1 |
| Akerman, S; Goadsby, PJ; Kaube, H | 1 |
| Akopian, AN; Flores, CM; Hargreaves, KM; Patwardhan, A; Price, TJ | 1 |
| Cruz, F | 1 |
| Evans, RM; Ross, RA; Scott, RH | 1 |
| de Lago, E; de Miguel, R; Fernández-Ruiz, J; Lastres-Becker, I; Ramos, JA | 1 |
| Bátkai, S; Kunos, G; Pacher, P | 1 |
| Balali-Mood, K; Bond, SM; McQueen, DS; Smart, D; Smith, PJ | 1 |
| Adler-Graschinsky, E; Becu-Villalobos, D; Celuch, SM; Huidobro-Toro, JP; Orliac, ML; Peroni, RN | 1 |
| Li, J; Maile, MD; Sinoway, AN; Sinoway, LI | 1 |
| Cannizzaro, C; D'Amico, M; Martire, M; Preziosi, P | 2 |
| Fujita, T; Kawasaki, Y; Kumamoto, E; Yue, HY | 1 |
| Appendino, G; Campi, B; Daddario, N; De Petrocellis, L; Di Marzo, V; Fontana, G; Gazzieri, D; Geppetti, P; Ligresti, A; Minassi, A; Moriello, AS; Pinna, C; Trevisani, M | 1 |
| Bembry, J; Chen, Y; Golech, SA; Lenz, F; McCarron, RM; Mechoulam, R; Shohami, E; Spatz, M | 1 |
| Avelino, A; Bevan, S; Charrua, A; Cruz, F; Dinis, P; Nagy, I; Yaqoob, M | 1 |
| Chung, ES; Jin, BK; Kim, SR; Kim, SU; Lee, DY; Oh, UT | 1 |
| Bianchi, R; Borsani, E; Buffoli, B; Rezzani, R; Ricci, F; Rodella, LF | 1 |
| Lam, PM; Lambert, DG; McDonald, J | 1 |
| Caterina, M; Cowan, A; Inan, S; Oppenheim, JJ; Rogers, TJ; Sun, R; Wang, JM; Zhang, N | 1 |
| Horie, S; Ishihara, S; Minowa, S; Murayama, T; Tsuchiya, S | 1 |
| Blumberg, PM; Choi, HK; Jin, MK; Kang, SU; Kedei, N; Lee, J; Pearce, LV; Tóth, A; Tran, R; Wang, Y | 1 |
| Kendall, DA; O'Sullivan, SE; Randall, MD | 1 |
| Ahern, GP; Brooks, IM; Miyares, RL; Wang, XB | 1 |
| Andersson, TL; Evilevitch, V; Högestätt, ED; Jönsson, BA; Movahed, P; Wollmer, P; Zygmunt, PM | 1 |
| Lee, MG; Undem, BJ; Weinreich, D | 1 |
| Birnir, B; Ermund, A; Högestätt, ED; Jönsson, BA; Jørgensen, TD; Movahed, P; Sterner, O; Wingstrand, JA; Zygmunt, PM | 1 |
| Adler-Graschinsky, E; Briones, R; Huidobro-Toro, JP; Orliac, ML; Poblete, IM | 1 |
| Abe, T; Arisaka, O; Morimoto, H; Ohori, M; Yamada, Y; Yoshihara, S | 1 |
| Farthing, JN; Gutierrez, T; Hohmann, AG; Suplita, RL | 1 |
| Kaminski, NE; Wang, DH; Wang, Y | 2 |
| Nagy, I; Sántha, P; Singh Tahim, A | 1 |
| Bisogno, T; Di Marzo, V; Giros, B; Li, DL; Moutsimilli, L; Nomikos, GG; Phebus, LA; Tzavara, ET | 1 |
| Bifulco, M; Bisogno, T; Di Marzo, V; Grimaldi, C; Laezza, C; Lechler, RI; Malfitano, AM; Matarese, G; Pisanti, S | 1 |
| Cabranes, A; de Lago, E; Di Marzo, V; Fernández-Ruiz, J; Fezza, F; García-Merino, A; Mestre, L; Ramos, JA; Sánchez, A; Valenti, M; Venderova, K | 1 |
| Bagi, Z; Blumberg, PM; Edes, I; Kedei, N; Lizanecz, E; Papp, Z; Pásztor, ET; Tóth, A | 1 |
| Adler-Graschinsky, E; Celuch, SM; García, Mdel C | 1 |
| Cowan, A; Ding, Z; Rawls, SM | 1 |
| Avelino, A; Cruz, F | 1 |
| Harada, N; Isobe, H; Okajima, K; Uchiba, M | 1 |
| Akerman, S; Goadsby, PJ; Holland, PR | 1 |
| Beaulieu, P; De Léan, A; Guindon, J; LoVerme, J; Piomelli, D | 1 |
| Baik, SK; Dehpour, AR; Gaskari, SA; Lee, SS; Liu, H; Moezi, L | 1 |
| Li, J; Wang, DH | 1 |
| Harada, N; Okajima, K | 2 |
| Ali, N; Chapman, V; Chimenti, M; de Lago, E; Fernandez-Ruiz, J; Kendall, DA; Millns, PJ; Ryland, E | 1 |
| Lam, FF; Luk, PW; Ng, ES | 1 |
| Johansen, ME; Lanza, DL; Moos, PJ; Reilly, CA; Sabnis, AS; Thomas, KC; Yost, GS | 1 |
| Wang, DH; Wang, Y | 1 |
| Bifulco, M; De Petrocellis, L; Eletto, D; Gazzerro, P; Husain, S; Laezza, C; Malfitano, AM; Orlando, P; Schwalb, M; Terskiy, A; Toruner, GA; Vitale, E | 1 |
| Davies, J; Hainsworth, AH; Lam, PM; Lambert, DG; Owen, DE; Smith, GD | 1 |
| Cristino, L; Davison, JS; Di Marzo, V; Guglielmotti, V; Oland, LD; Pittman, QJ; Sharkey, KA; Starowicz, K; Van Sickle, MD | 1 |
| Bianchi, R; Borsani, E; Labanca, M; Rodella, LF | 1 |
| Benedek, G; Horvath, G; Kekesi, G; Nagy, E | 1 |
| Fischbach, T; Greffrath, W; Nawrath, H; Treede, RD | 1 |
| Chancellor, MB; de Groat, WC; Kitada, C; Saitoh, C; Uchida, W; Yoshimura, N | 1 |
| Agrò, AF; Bagetta, G; Bari, M; Cerulli, A; Corasaniti, MT; De Simone, C; Gasperi, V; Maccarrone, M; Morrone, LA; Nucci, C; Tartaglione, R; Terrinoni, A | 1 |
| Bilbao, A; Ciccocioppo, R; Cippitelli, A; Gorriti, MA; Massi, M; Navarro, M; Piomelli, D; Rodríguez de Fonseca, F | 1 |
| Herradón, E; López-Miranda, V; Martín, MI | 1 |
| Cassano, T; Cuomo, V; Giuffrida, A; Morgese, MG | 1 |
| Anderson, S; Cohen, DM; Fu, Y; Oyama, TT; Tian, W; Xu, H | 1 |
| Bok, E; Chung, ES; Chung, YC; Jin, BK; Kim, SR; Park, ES; Park, KW; Won, SY | 1 |
| Garry, MG; Mitchell, JH; O'Brien, DE; Smith, SA; Williams, MA | 1 |
| Faltynek, CR; Jarvis, MF; Neelands, TR; Surowy, CS | 1 |
| Bernardi, G; Centonze, D; De Chiara, V; Maccarrone, M; Musella, A; Prosperetti, C; Rossi, S | 1 |
| Evans, S; Fan, J; Hong, S; Kemmerer, ES; Li, Y; Wiley, JW | 1 |
| Bellini, G; De Petrocellis, L; Di Marzo, V; Luongo, L; Maione, S; Nobili, B; Perrotta, S; Petrosino, S; Rossi, F; Santoro, C; Siniscalco, D; Torella, M | 1 |
| Randall, MD; Wheal, AJ | 1 |
| Avelino, A; Cruz, F; Cunha, RA; Ferreira, SG; Köfalvi, A; Lomaglio, T; Oliveira, CR | 1 |
| Bien, MY; Ho, CY; Kou, YR; Lin, RL; Lin, YS | 1 |
| Alenmyr, L; Greiff, L; Högestätt, ED; Zygmunt, PM | 1 |
| Brink, TS; Potenzieri, C; Simone, DA | 1 |
| Gregg, RG; Heimel, JA; Kamermans, M; Nawy, S; Peachey, NS; Shen, Y | 1 |
| Mahmud, A; Nagy, I; Paule, CC; Santha, P | 1 |
| Antonangelo, C; Barbonetti, A; Barboni, B; Battista, N; Catanzaro, G; Francavilla, F; Maccarrone, M; Pasquariello, N; Rapino, C; Vassallo, MR | 1 |
| Campos, AC; Guimarães, FS | 1 |
| Bhaskaran, MD; Smith, BN | 1 |
| Bernardi, G; Cantarella, C; Castelli, M; Cavasinni, F; Centonze, D; De Chiara, V; Mataluni, G; Musella, A; Rossi, S | 1 |
| Davies, JW; Guerin, CJ; Hainsworth, AH; Lambert, DG | 1 |
| Jenes, A; Nagy, I; Sántha, P; Somogyi, C | 1 |
| Alexander, SP; Randall, MD; Wheal, AJ | 1 |
| Mlynarczyk, M; Nagy, I; Paule, CC; Soneji, ND | 1 |
| Christie, MJ; Drew, GM; Kawahara, H; Vaughan, CW | 1 |
| De Chiaro, M; de Novellis, V; De Petrocellis, L; Di Marzo, V; Guida, F; Maione, S; Moriello, AS; Piscitelli, F | 1 |
| Albrecht, D; Gebhardt, C; Kulisch, C; von Bohlen Und Halbach, O; Zschenderlein, C | 1 |
| Almeida, MC; Balaskó, M; Dogan, MD; Eales, J; Gavva, NR; Molchanova, AY; Oliveira, DL; Patel, S; Pétervári, E; Romanovsky, AA; Steiner, AA; Székely, M; Wanner, SP | 1 |
| Becker, C; Engel, MA; Izydorczyk, I; Mueller-Tribbensee, SM; Neurath, MF; Reeh, PW | 1 |
| Buzas, K; Cohen, JI; Fan, H; Howard, OM; Klinman, D; Mont, E; Oppenheim, JJ; Qi, J; Wang, K | 1 |
| Hayase, T | 1 |
| Reeh, PW; Sauer, SK; Weller, K | 1 |
| Alenmyr, L; Greiff, L; Herrmann, A; Högestätt, ED; Zygmunt, PM | 1 |
| Boczán, J; Czikora, Á; Daragó, A; Édes, I; Lizanecz, E; Papp, Z; Tóth, A | 1 |
| Chen, XJ; Du, XN; Huang, DY; Jia, ZF; Liu, BY; Zhang, GH; Zhang, HL; Zhang, X | 1 |
| Baranowska-Kuczko, M; Kozłowska, H; MacLean, MR; Malinowska, B | 1 |
| Ichikawa, H; Muramatsu, T; Sahara, Y; Sato, M; Shibukawa, Y; Sobhan, U; Tazaki, M; Tsumura, M | 1 |
| Chirasani, SR; Cravatt, BF; Cristino, L; De Petrocellis, L; Di Marzo, V; Dittmar, G; Glass, R; Gurok, U; Imperatore, R; Kettenmann, H; Kumar, J; Lewin, GR; Ligresti, A; Matyash, V; Momma, S; Nuber, UA; Petrosino, S; Purfürst, B; Smith, ES; Stock, K; Synowitz, M; Wälzlein, JH; Wend, P | 1 |
| Cunha, JM; Jesus, CH; Neufeld, M; Schreiber, AK | 1 |
| Aguiar, DC; Fogaça, MV; Gomes, FV; Guimarães, FS; Moreira, FA | 1 |
| Bartho, L; Benko, R; Dékány, A; Szombati, V | 1 |
| Ho, WS | 1 |
| Correia-da-Silva, G; Costa, MA; Fonseca, BM; Keating, E; Teixeira, NA | 1 |
| Binkowski, M; Czaja, M; Di Marzo, V; Kolosowska, N; Makuch, W; Malek, N; Morera, E; Mrugala, M; Przewlocka, B; Starowicz, K | 1 |
| D'Agostino, B; de Novellis, V; Di Marzo, V; Guida, F; Luongo, L; Maione, S; Matteis, M; Palazzo, E; Petrosino, S; Rossi, F; Spaziano, G; Sullo, N | 1 |
| Batista, PA; Fogaça, MV; Guimarães, FS | 1 |
| Charrua, A; Di Marzo, V; Martins, D; Morgado, C; Piscitelli, F; Silva, M; Tavares, I | 1 |
| Deák, É; Dux, M; Jancsó, G; Sántha, P; Tassi, N | 1 |
| da-Silva, CA; Del-Bel, E; Dos-Santos-Pereira, M; Guimarães, FS | 1 |
| Chen, M; Li, J; Li, M; Liu, B; Luo, L; Xin, J; Yin, W | 1 |
| Balbay, E; Çiğ, B; Nazıroğlu, M; Taner, AN | 1 |
| Pang, G; Song, P; Xiao, S; Xie, J; Zhang, Y | 1 |
| Garg, SK; Kumar, A; Mishra, AK; Saxena, A; Singh, V; Swain, DK; Yadav, S | 1 |
| González-Anduaga, GM; López-Ortíz, M; Navarrete, A; Palomino-Hernández, O; Quiñonez-Bastidas, GN; Regla, I; Rocha-González, HI | 1 |
| Battista, N; Maccarrone, M; Mosca, F; Tiscar, PG; Zarivi, O | 1 |
| Manna, SSS | 1 |
| Ramsay, S; Spencer, NJ; Zagorodnyuk, V | 1 |
10 review(s) available for capsaicin and anandamide
| Article | Year |
|---|---|
Sensing with TRP channels.
Topics: Animals; Humans; Ligands; Models, Biological; Phylogeny; Temperature; Transient Receptor Potential Channels | 2005 |
New perspectives on enigmatic vanilloid receptors.
Topics: Animals; Arachidonic Acids; Brain Chemistry; Cannabinoid Receptor Modulators; Capsaicin; Diterpenes; Drug Design; Endocannabinoids; Forecasting; Ganglia, Spinal; Glycerides; Humans; Ligands; Nerve Tissue Proteins; Neurons, Afferent; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Structure-Activity Relationship | 2000 |
Anandamide: some like it hot.
Topics: Animals; Arachidonic Acids; Brain; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Humans; Neurons, Afferent; Polyunsaturated Alkamides; Receptors, Drug | 2001 |
Vanilloid (capsaicin) receptors in health and disease.
Topics: Animals; Arachidonic Acids; Capsaicin; Disease; Diterpenes; Drug Therapy; Endocannabinoids; Health; Humans; Neurons; Pathology; Polyunsaturated Alkamides; Receptors, Drug | 2002 |
Functional morphology and physiology of slowly adapting pulmonary stretch receptors.
Topics: Adaptation, Physiological; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Humans; Lung; Neural Conduction; Polyunsaturated Alkamides; Pulmonary Stretch Receptors; Receptors, Drug; Reflex; Vagus Nerve | 2003 |
Functional morphology and physiological properties of bronchopulmonary C-fiber afferents.
Topics: Afferent Pathways; Animals; Arachidonic Acids; Bronchi; Cannabinoids; Capsaicin; Endocannabinoids; Humans; Irritants; Lung; Nerve Fibers, Unmyelinated; Neurons, Afferent; Polyunsaturated Alkamides; Receptors, Drug | 2003 |
Mechanisms involved in new therapies for overactive bladder.
Topics: Animals; Arachidonic Acids; Botulinum Toxins, Type A; Capsaicin; Diterpenes; Endocannabinoids; Humans; Nerve Growth Factor; Neurotoxins; Polyunsaturated Alkamides; Receptors, Drug; Urinary Bladder; Urinary Incontinence | 2004 |
TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications.
Topics: Animals; Arachidonic Acids; Capsaicin; Clinical Trials as Topic; Cystitis; Diterpenes; Endocannabinoids; Humans; Neurons, Afferent; Polyunsaturated Alkamides; TRPV Cation Channels; Urinary Tract; Urothelium | 2006 |
Neural control of blood pressure: focusing on capsaicin-sensitive sensory nerves.
Topics: Animals; Antihypertensive Agents; Arachidonic Acids; Blood Pressure; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Endothelins; Humans; Hypertension; Neurons, Afferent; Polyunsaturated Alkamides; Reactive Oxygen Species; Renin-Angiotensin System; Sodium, Dietary; Sympathetic Nervous System; TRPV Cation Channels | 2007 |
Roles of transient receptor potential vanilloid subtype 1 and cannabinoid type 1 receptors in the brain: neuroprotection versus neurotoxicity.
Topics: Animals; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Neuroprotective Agents; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Sensory System Agents; TRPV Cation Channels | 2007 |
1 trial(s) available for capsaicin and anandamide
| Article | Year |
|---|---|
TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.
Topics: Acrolein; Administration, Intranasal; Adult; Aged; Arachidonic Acids; Biopsy; Calcium; Calcium Channels; Capsaicin; Cilia; Cross-Over Studies; Double-Blind Method; Endocannabinoids; Humans; Immunohistochemistry; Methanol; Middle Aged; Movement; Mucin 5AC; Mucin-5B; Mustard Plant; Nasal Lavage; Nasal Mucosa; Nerve Tissue Proteins; Pain; Pain Measurement; Plant Oils; Polyunsaturated Alkamides; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sensory System Agents; Sweden; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult | 2011 |
187 other study(ies) available for capsaicin and anandamide
| Article | Year |
|---|---|
Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.
Topics: Amides; Animals; Cell Line; Fatty Acids; Humans; Ligands; Molecular Conformation; Protein Binding; Receptors, Cannabinoid; Stereoisomerism; Substrate Specificity; TRPV Cation Channels | 2009 |
Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capillary Permeability; Capsaicin; Carrageenan; Edema; Endocannabinoids; Hindlimb; Hyperalgesia; Male; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Skin | 1998 |
Antihyperalgesic effects of spinal cannabinoids.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoids; Capsaicin; Carrageenan; Cyclohexanols; Endocannabinoids; Injections, Spinal; Male; Mice; Pain Threshold; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Spinal Cord | 1998 |
Interactions between synthetic vanilloids and the endogenous cannabinoid system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Cell Line; Endocannabinoids; Kinetics; Leukemia, Basophilic, Acute; Macrophages; Mice; Neuroblastoma; Polyunsaturated Alkamides; Rats; Receptors, Drug; Tumor Cells, Cultured | 1998 |
Anandamide transport inhibition by the vanilloid agonist olvanil.
Topics: Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Astrocytoma; Biological Transport; Brain; Capsaicin; Depression, Chemical; Endocannabinoids; Humans; Polyunsaturated Alkamides; Rats; Receptors, Drug; Tumor Cells, Cultured | 1999 |
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide.
Topics: Animals; Arachidonic Acids; Basilar Artery; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium Channels; Capsaicin; Cell Line; Endocannabinoids; Female; Guinea Pigs; Hepatic Artery; In Vitro Techniques; Neurons, Afferent; Peptide Fragments; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Recombinant Proteins; Vasodilator Agents; Xenopus | 1999 |
Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Binding Sites; Biological Transport; Capsaicin; Cell Division; Cell Line; Cell Membrane; Diffusion; Electric Conductivity; Endocannabinoids; Fatty Acids, Unsaturated; Humans; Ligands; Mice; Oocytes; Polyunsaturated Alkamides; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Xenopus laevis | 1999 |
The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1).
Topics: Amides; Arachidonic Acids; Binding, Competitive; Calcium; Calcium Channels; Cannabinoids; Capsaicin; Cell Line; Cloning, Molecular; Electrophysiology; Endocannabinoids; Ethanolamines; Humans; Hydrogen-Ion Concentration; Palmitic Acids; Patch-Clamp Techniques; Polyunsaturated Alkamides; Receptors, Drug; Recombinant Proteins; TRPV Cation Channels | 2000 |
Anandamide: an endogenous activator of the vanilloid receptor.
Topics: Animals; Arachidonic Acids; Cannabinoids; Capsaicin; Endocannabinoids; Humans; Ligands; Polyunsaturated Alkamides; Receptors, Drug | 2000 |
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acids; Behavior, Animal; Capsaicin; Carrageenan; Cells, Cultured; Electrophysiology; Endocannabinoids; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Targeting; Hot Temperature; Hydrogen-Ion Concentration; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain; Polyunsaturated Alkamides; Receptors, Drug; Stem Cells; TRPV Cation Channels | 2000 |
The anandamide transport inhibitor AM404 activates vanilloid receptors.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoids; Capsaicin; Endocannabinoids; Female; Hepatic Artery; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oocytes; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Drug; Rimonabant; Vasodilation; Xenopus | 2000 |
Interacting effects of capsaicin and anandamide on intracellular calcium in sensory neurones.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Fluorescent Dyes; Fura-2; Intracellular Membranes; Neurons, Afferent; Polyunsaturated Alkamides; Rats; Rats, Wistar | 2000 |
Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Endothelium, Vascular; Glycopeptides; In Vitro Techniques; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mesenteric Arteries; Metalloendopeptidases; Muscle, Smooth, Vascular; Peptides, Cyclic; Phenanthrolines; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilator Agents | 2000 |
Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity.
Topics: Animals; Arachidonic Acids; Binding, Competitive; Biological Transport; Calcium; Capsaicin; Cell Line; Dose-Response Relationship, Drug; Endocannabinoids; Humans; Ligands; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; TRPV Cation Channels; Tumor Cells, Cultured | 2000 |
Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide.
Topics: Analgesics; Animals; Arachidonic Acids; Behavior, Animal; Brain; Cannabinoid Receptor Modulators; Capsaicin; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Endocannabinoids; Glycerides; Male; Mice; Mice, Inbred ICR; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug | 2000 |
Bidirectional control of airway responsiveness by endogenous cannabinoids.
Topics: Animals; Arachidonic Acids; Axons; Bronchi; Bronchial Spasm; Bronchoconstriction; Cannabinoids; Capsaicin; Cough; Endocannabinoids; Guinea Pigs; Lung; Muscle Contraction; Muscle, Smooth; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints.
Topics: Animals; Arachidonic Acids; Arthritis, Experimental; Calcium Channel Blockers; Capsaicin; Disease Models, Animal; Drug Interactions; Endocannabinoids; Knee Joint; Male; Nociceptors; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Drug; Treatment Outcome; TRPV Cation Channels | 2001 |
Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens.
Topics: Animals; Arachidonic Acids; Benzoxazines; Binding, Competitive; Biological Transport; Calcium; Calcium Channel Blockers; Cannabinoids; Capsaicin; CHO Cells; Cricetinae; Drug Interactions; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Male; Mice; Morpholines; Muscle Contraction; Naphthalenes; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Structure-Activity Relationship; Transfection; TRPV Cation Channels; Vas Deferens | 2001 |
Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Endocannabinoids; Ganglia, Spinal; In Vitro Techniques; Male; Neurons, Afferent; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Receptors, Cannabinoid; Receptors, Drug; Spinal Cord; Substance P; TRPV Cation Channels | 2001 |
Regional differences in anandamide- and methanandamide-induced membrane potential changes in rat mesenteric arteries.
Topics: Animals; Arachidonic Acids; Benzoxazines; Biological Factors; Calcium Channel Blockers; Cannabinoids; Capsaicin; Electrophysiology; Endocannabinoids; Endothelium, Vascular; Membrane Potentials; Mesenteric Arteries; Morpholines; Muscle, Smooth, Vascular; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Drug; Rimonabant; Vasodilator Agents | 2001 |
Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands.
Topics: Animals; Arachidonic Acids; Benzoxazines; Binding, Competitive; Calcium; Capsaicin; Cell Line; Cyclohexanols; Cytosol; Dose-Response Relationship, Drug; Endocannabinoids; Humans; Ligands; Membranes; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Structure-Activity Relationship; Tritium; TRPV Cation Channels; Tumor Cells, Cultured | 2001 |
The endogenous cannabinoid agonist, anandamide stimulates sensory nerves in guinea-pig airways.
Topics: Animals; Arachidonic Acids; Bronchi; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Guinea Pigs; Male; Neurons, Afferent; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug | 2001 |
Effect of vanilloid drugs on gastrointestinal transit in mice.
Topics: Alkaloids; Animals; Arachidonic Acids; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Gastrointestinal Transit; Hexamethonium; Male; Mice; Mice, Inbred ICR; Naloxone; NG-Nitroarginine Methyl Ester; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Drug; Rimonabant; Yohimbine | 2001 |
The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism.
Topics: Arachidonic Acids; Biological Transport; Calcium; Cannabinoids; Capsaicin; Cell Line; Cell Membrane; Cytosol; Diterpenes; Endocannabinoids; Enzyme Inhibitors; Humans; Kinetics; Nitroprusside; Organophosphonates; Polyunsaturated Alkamides; Receptors, Drug; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transfection | 2001 |
Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology.
Topics: Alkaloids; Aniline Compounds; Arachidonic Acids; Benzophenanthridines; Calcium; Capsaicin; Cell Line; Diterpenes; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Fluorescence; Fluorometry; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Phenanthridines; Polycyclic Sesquiterpenes; Polyunsaturated Alkamides; Protein Kinase C; Receptors, Drug; Ruthenium Red; Sesquiterpenes; Time Factors; Xanthenes | 2001 |
Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Binding, Competitive; Cannabinoid Receptor Modulators; Capsaicin; Cell Line; Dose-Response Relationship, Drug; Endocannabinoids; Humans; Motor Activity; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Stereotyped Behavior; Transfection | 2001 |
Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Capsaicin; Endocannabinoids; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Morpholines; Naphthalenes; Nerve Fibers; Neural Inhibition; Neurons; Patch-Clamp Techniques; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Rats, Wistar; Substantia Gelatinosa | 2001 |
Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide.
Topics: Animals; Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Capsaicin; Cell Line; Dose-Response Relationship, Drug; Endocannabinoids; Gene Expression; Humans; Polyunsaturated Alkamides; Rats; Receptors, Drug; Recombinant Proteins; Ruthenium Red; Temperature | 2001 |
Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Biological Transport; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Female; Intraocular Pressure; Male; Polyunsaturated Alkamides; Rabbits; Rats; Rats, Wistar | 2001 |
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation | 2001 |
Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide.
Topics: Animals; Arachidonic Acids; Calcium; Capsaicin; Cell Line; Cells, Cultured; Electrophysiology; Endocannabinoids; Enzyme Activation; Ganglia, Spinal; Hot Temperature; Humans; Ion Channel Gating; Neurons; Polyunsaturated Alkamides; Protein Kinase C; Protons; Rats; Rats, Wistar; Receptors, Drug; Tetradecanoylphorbol Acetate | 2001 |
Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.
Topics: Amides; Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acids; Blotting, Western; Breast Neoplasms; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Cell Division; Colforsin; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Glycerides; Humans; Hydrolysis; Inhibitory Concentration 50; Palmitic Acids; Polyunsaturated Alkamides; Protein Binding; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured | 2001 |
A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Bronchi; Calcium Channel Blockers; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; In Vitro Techniques; Indomethacin; Lipoxygenase; Muscle Contraction; Oxazepines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Drug; Rimonabant; Thiorphan | 2001 |
Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors.
Topics: Acetylcholine; Animals; Arachidonic Acids; Camphanes; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Electric Stimulation; Endocannabinoids; Guinea Pigs; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Phenylmethylsulfonyl Fluoride; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat.
Topics: Anesthetics; Animals; Arachidonic Acids; Blood Pressure; Calcium Channel Blockers; Capsaicin; Cardiovascular System; Endocannabinoids; Male; Neurons, Afferent; Polyunsaturated Alkamides; Pulmonary Ventilation; Rats; Rats, Wistar; Reflex; Respiratory System | 2001 |
Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors.
Topics: Amides; Arachidonic Acids; Calcium; Capsaicin; Cell Line; Diterpenes; Drug Synergism; Endocannabinoids; Ethanolamines; Humans; Palmitic Acids; Polyunsaturated Alkamides; Receptors, Drug | 2001 |
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.
Topics: Amidohydrolases; Arachidonic Acids; Binding, Competitive; Biological Transport; Calcium; Cannabidiol; Capsaicin; Cell Line; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Endocannabinoids; Gene Expression; Humans; Hydrolysis; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug | 2001 |
Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries.
Topics: Amides; Animals; Arachidonic Acids; Capsaicin; Coronary Vessels; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Ethanolamines; Gap Junctions; Glycyrrhetinic Acid; In Vitro Techniques; Indoles; Indomethacin; Male; Palmitic Acids; Peptides; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Tetraethylammonium; Vasodilation | 2001 |
Cannabinoid activation of recombinant and endogenous vanilloid receptors.
Topics: Acetylcholine; Animals; Arachidonic Acids; Benzofurans; Calcitonin Gene-Related Peptide; Calcium; Calcium Channel Blockers; Camphanes; Cannabinoids; Capsaicin; Cell Line; Dose-Response Relationship, Drug; Endocannabinoids; Humans; In Vitro Techniques; Mesenteric Arteries; Neurons, Afferent; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Ruthenium; Synaptic Transmission; Vasodilation; Vasodilator Agents | 2001 |
Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Animals; Apamin; Arachidonic Acid; Arachidonic Acids; Barium; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Potassium; Potassium Channel Blockers; Potassium Channels; Pyrazoles; Receptors, Drug; Rimonabant; Sheep; Tetraethylammonium; Vasoconstrictor Agents; Vasodilation | 2001 |
The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice.
Topics: Action Potentials; Animals; Arachidonic Acids; Cannabinoids; Capsaicin; Diterpenes; Endocannabinoids; Glycerides; Hippocampus; In Vitro Techniques; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Drug | 2001 |
Anandamide and methanandamide induce both vanilloid VR1- and cannabinoid CB1 receptor-mediated changes in heart rate and blood pressure in anaesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Arachidonic Acids; Blood Pressure; Calcium Channel Blockers; Cannabinoids; Capsaicin; Endocannabinoids; Heart Rate; Male; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug | 2001 |
CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord.
Topics: Adjuvants, Immunologic; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Mice; Nociceptors; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Receptors, Neurokinin-1; Rimonabant; Spinal Cord; Substance P | 2002 |
A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Carrier Proteins; Cytosol; Endocannabinoids; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Motor Activity; Pain Measurement; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug | 2002 |
Anandamide inhibits excitatory transmission to rat substantia gelatinosa neurones in a manner different from that of capsaicin.
Topics: Animals; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Electric Stimulation; Endocannabinoids; Excitatory Postsynaptic Potentials; Glutamic Acid; Nerve Fibers; Nerve Fibers, Myelinated; Neural Conduction; Nociceptors; Pain; Polyunsaturated Alkamides; Rats; Substantia Gelatinosa; Synaptic Transmission | 2002 |
Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Biological Factors; Capsaicin; Drug Synergism; Endocannabinoids; Enzyme Inhibitors; Gap Junctions; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Ruthenium Red; Vasodilation; Vasodilator Agents | 2002 |
Stimulation of pulmonary vagal C-fibres by anandamide in anaesthetized rats: role of vanilloid type 1 receptors.
Topics: Afferent Pathways; Animals; Arachidonic Acids; Capsaicin; Cardiovascular System; Chemoreceptor Cells; Dose-Response Relationship, Drug; Electrophysiology; Endocannabinoids; Lung; Male; Morpholines; Nerve Fibers; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reflex; TRPV Cation Channels; Vagus Nerve | 2002 |
Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent.
Topics: Animals; Aorta; Arachidonic Acids; Cannabinoids; Capsaicin; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Gap Junctions; GTP-Binding Proteins; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rabbits; Receptors, Calcitonin Gene-Related Peptide; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Virulence Factors, Bordetella | 2002 |
'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism.
Topics: Arachidonic Acids; Calcium; Capsaicin; Cell Line; Endocannabinoids; Ethanolamines; Humans; Polyunsaturated Alkamides; Receptors, Drug | 2002 |
Mechanisms underlying tissue selectivity of anandamide and other vanilloid receptor agonists.
Topics: Animals; Arachidonic Acids; Bronchi; Bronchial Arteries; Calcium Channel Blockers; Capsaicin; Computer Simulation; Endocannabinoids; Guinea Pigs; Lung; Male; Mesenteric Arteries; Polyunsaturated Alkamides; Receptors, Drug | 2002 |
Characterization of the anandamide induced depolarization of guinea-pig isolated vagus nerve.
Topics: Action Potentials; Animals; Arachidonic Acids; Calcium; Capsaicin; Electrophysiology; Endocannabinoids; Enzyme Activators; Guinea Pigs; In Vitro Techniques; Lipoxygenase Inhibitors; Microscopy, Confocal; Polyunsaturated Alkamides; Protein Kinase C; Receptors, Cannabinoid; Receptors, Drug; Vagus Nerve | 2002 |
Arachidonic acid release and prostaglandin F(2alpha) formation induced by anandamide and capsaicin in PC12 cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Chloride; Capsaicin; Dinoprost; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Activators; Extracellular Space; Intercellular Signaling Peptides and Proteins; Ionomycin; Ionophores; PC12 Cells; Peptides; Phospholipases A; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Wasp Venoms | 2002 |
Nitric oxide is involved in the relaxant effect of capsaicin in the human sigmoid colon circular muscle.
Topics: Arachidonic Acids; Cannabinoids; Capsaicin; Colon, Sigmoid; Endocannabinoids; Humans; In Vitro Techniques; Muscle Relaxation; Muscles; Nitric Oxide; Polyunsaturated Alkamides | 2002 |
Anandamide induces cough in conscious guinea-pigs through VR1 receptors.
Topics: Aerosols; Animals; Arachidonic Acids; Calcium; Camphanes; Capsaicin; Cells, Cultured; Consciousness; Cough; Dronabinol; Endocannabinoids; Excitatory Amino Acid Antagonists; Guinea Pigs; Male; Nodose Ganglion; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2002 |
A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding.
Topics: Animals; Appetite Regulation; Arachidonic Acids; Behavior, Animal; Benzoxazines; Brain; Cannabinoid Receptor Modulators; Capsaicin; Denervation; Dose-Response Relationship, Drug; Drug Synergism; Eating; Endocannabinoids; Feeding Behavior; Gastric Mucosa; Hyperphagia; Injections, Intraperitoneal; Injections, Intraventricular; Intestine, Small; Male; Morpholines; Naphthalenes; Oleic Acid; Oleic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Satiety Response | 2002 |
Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; Capsaicin; Cells, Cultured; Clone Cells; Endocannabinoids; Ganglia, Spinal; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug | 2002 |
Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Blood Pressure; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Endotoxemia; Enzyme Inhibitors; Lipopolysaccharides; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Phenylmethylsulfonyl Fluoride; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Drug; Shock, Septic; Splanchnic Circulation; Vasoconstrictor Agents | 2003 |
Concentration-dependent dual effect of anandamide on sensory neuropeptide release from isolated rat tracheae.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; In Vitro Techniques; Male; Neuropeptides; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Reference Values; Reproducibility of Results; Rimonabant; Sensitivity and Specificity; Somatostatin; Substance P; Trachea | 2003 |
Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Endocannabinoids; Male; Neurons, Afferent; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Capsaicin; Electric Stimulation; Electrophysiology; Endocannabinoids; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; In Vitro Techniques; Medulla Oblongata; Membrane Potentials; Nerve Endings; Patch-Clamp Techniques; Polyunsaturated Alkamides; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion | 2003 |
Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells.
Topics: Action Potentials; Animals; Arachidonic Acids; Calcium Channels, L-Type; Capsaicin; Cell Line; Delayed Rectifier Potassium Channels; Drug Interactions; Endocannabinoids; Glycerol; Hybrid Cells; Mice; Neurons; omega-Conotoxin GVIA; Pertussis Toxin; Polyunsaturated Alkamides; Potassium Channels; Potassium Channels, Voltage-Gated; Rats | 2003 |
N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia.
Topics: Animals; Arachidonic Acids; Brain; Calcium; Calcium Channel Blockers; Capsaicin; Cattle; Cell Line; Cell Membrane; Cytosol; Diterpenes; Dopamine; Dose-Response Relationship, Drug; Endocannabinoids; Humans; Hyperalgesia; Inhibitory Concentration 50; Ions; Lipids; Male; Mass Spectrometry; Models, Chemical; Polyunsaturated Alkamides; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Drug; Temperature; Time Factors; TRPV Cation Channels | 2003 |
Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry.
Topics: Animals; Arachidonic Acids; Baculoviridae; Barium; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cannabinoids; Capsaicin; Cells, Cultured; Diterpenes; Endocannabinoids; Endoplasmic Reticulum; Enzyme Inhibitors; Humans; Immunoblotting; Ion Transport; Microscopy, Confocal; Neurotoxins; Polyunsaturated Alkamides; Rats; Receptors, Drug; Recombinant Proteins; Thapsigargin; Transfection; TRPV Cation Channels; Type C Phospholipases | 2003 |
N-Morpholino- and N-diethyl-analogues of palmitoylethanolamide increase the sensitivity of transfected human vanilloid receptors to activation by anandamide without affecting fatty acid amidohydrolase activity.
Topics: Amides; Amidohydrolases; Animals; Arachidonic Acids; Brain Neoplasms; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Ethanolamines; Glioma; Humans; In Vitro Techniques; Kidney; Morpholines; Palmitic Acids; Polyunsaturated Alkamides; Radioligand Assay; Rats; Receptor, Cannabinoid, CB1; Receptors, Drug; Transfection; Tumor Cells, Cultured | 2003 |
Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor.
Topics: Animals; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Endocannabinoids; Hypertension; Male; Mesenteric Arteries; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Evidence against the presence of an anandamide transporter.
Topics: Arachidonic Acids; Astrocytoma; Biological Transport; Cannabinoids; Capsaicin; Carrier Proteins; Endocannabinoids; Humans; Immunohistochemistry; Kinetics; Neuroblastoma; Polyunsaturated Alkamides; Tumor Cells, Cultured | 2003 |
Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; Capsaicin; Diterpenes; Dopamine; Dose-Response Relationship, Drug; Endocannabinoids; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Mesencephalon; Neurons; Patch-Clamp Techniques; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Drug; RNA, Messenger; Substantia Nigra; Synapses; Synaptic Transmission; Tetrodotoxin | 2003 |
Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated response.
Topics: Arachidonic Acids; Calcium; Calcium Channel Blockers; Cannabinoids; Capsaicin; Cyclic AMP; Dronabinol; Endocannabinoids; Humans; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug | 2003 |
Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channels; Capsaicin; Cell Line; CHO Cells; Cricetinae; Diterpenes; Dopamine; Dose-Response Relationship, Drug; Endocannabinoids; Humans; Kinetics; Ligands; Models, Chemical; Polyunsaturated Alkamides; Protein Binding; Rats; Receptors, Drug; Spinal Cord; Time Factors; Transfection | 2003 |
Activation of TRPV1 by the satiety factor oleoylethanolamide.
Topics: Animals; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Female; Ganglia, Spinal; Gene Expression; Membrane Potentials; Neurons, Afferent; Oleic Acid; Oleic Acids; Oocytes; Patch-Clamp Techniques; Polyunsaturated Alkamides; Protein Kinase C; Rats; Receptors, Drug; Satiety Response; Xenopus laevis | 2003 |
Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Blood Cells; Brain; Brain Chemistry; Brain Mapping; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Endocannabinoids; Ethanolamines; Fatty Acids, Unsaturated; Lipoxygenase; Male; Masoprocol; Nerve Degeneration; Neuroprotective Agents; Ouabain; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Drug | 2003 |
Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Cannabinoids; Capsaicin; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Ganglia, Spinal; In Vitro Techniques; Male; Nerve Growth Factor; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2003 |
Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Antihypertensive Agents; Arachidonic Acids; Benzoxazines; Blood Pressure; Calcium Channel Blockers; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Ganglionic Blockers; Heart Rate; Hemodynamics; Hexamethonium; Injections, Spinal; Male; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Drug; Rimonabant; Spinal Cord; Urethane | 2003 |
A novel neuroimmune mechanism in cannabinoid-mediated attenuation of nerve growth factor-induced hyperalgesia.
Topics: Analgesics; Animals; Arachidonic Acids; Cannabinoids; Capsaicin; Cell Movement; Endocannabinoids; Hyperalgesia; Male; Nerve Growth Factor; Neutrophils; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Rimonabant | 2003 |
Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro.
Topics: Amidohydrolases; Analysis of Variance; Animals; Animals, Newborn; Arachidonic Acids; Benzoxazines; Cannabinoids; Capsaicin; Drug Interactions; Electric Stimulation; Electrophysiology; Endocannabinoids; Excitatory Postsynaptic Potentials; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Long-Term Potentiation; Male; Morpholines; Naphthalenes; Neurons; Oleic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rimonabant; Sleep | 2004 |
Anandamide is able to inhibit trigeminal neurons using an in vivo model of trigeminovascular-mediated nociception.
Topics: Animals; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Endocannabinoids; Hypotension; Male; Neurons; Nitroprusside; Pain; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Trigeminal Caudal Nucleus; Vasodilation | 2004 |
Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide.
Topics: Aminobutyrates; Animals; Arachidonic Acid; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Dinoprostone; Diterpenes; Dopamine; Endocannabinoids; Ganglia, Spinal; Male; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Drug; Staurosporine; Trigeminal Ganglion; TRPC Cation Channels; TRPV Cation Channels | 2004 |
Multiple actions of anandamide on neonatal rat cultured sensory neurones.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Calcium Channels; Calcium Signaling; Capsaicin; Cells, Cultured; Drug Synergism; Endocannabinoids; Fura-2; Ganglia, Spinal; Neurons, Afferent; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Drug; Rimonabant; TRPV Cation Channels | 2004 |
Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Modulators; Capsaicin; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Interactions; Electrochemistry; Endocannabinoids; In Vitro Techniques; Ion Channels; Male; Motor Activity; Neurons; Polyunsaturated Alkamides; Potassium; Rats; Rats, Wistar; Receptors, Drug; Stereotyped Behavior; TRPV Cation Channels; Tyrosine 3-Monooxygenase | 2004 |
Haemodynamic profile and responsiveness to anandamide of TRPV1 receptor knock-out mice.
Topics: Animals; Arachidonic Acids; Blood Pressure; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Hypotension; Ion Channels; Male; Mice; Mice, Knockout; Neurons, Afferent; Polyunsaturated Alkamides; Reflex; Sympathetic Nervous System; TRPV Cation Channels; Ventricular Pressure | 2004 |
Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats.
Topics: Anesthesia; Animals; Arachidonic Acids; Blood Pressure; Cannabidiol; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Hyperventilation; Hypotension; Male; Polyunsaturated Alkamides; Pulmonary Ventilation; Rats; Rats, Wistar; Receptors, Drug | 2004 |
Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens.
Topics: Acetylcholine; Animals; Arachidonic Acids; Argentina; Capsaicin; Chile; Cycloheximide; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Estradiol; Estrogens; Female; Male; Mesentery; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Ovariectomy; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Sex Characteristics; Time Factors; Vasodilation | 2004 |
Muscle pressor reflex: potential role of vanilloid type 1 receptor and acid-sensing ion channel.
Topics: Acid Sensing Ion Channels; Animals; Arachidonic Acids; Baroreflex; Blood Pressure; Capsaicin; Diterpenes; Endocannabinoids; Heart Rate; Ion Channels; Lactic Acid; Male; Membrane Proteins; Muscle, Skeletal; Nerve Tissue Proteins; Neurotoxins; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Sodium Channels; TRPV Cation Channels | 2004 |
Inhibition by anandamide and synthetic cannabimimetics of the release of [3H]D-aspartate and [3H]GABA from synaptosomes isolated from the rat hippocampus.
Topics: Animals; Arachidonic Acids; Aspartic Acid; Calcium; Cannabinoid Receptor Agonists; Cannabinoids; Capsaicin; Cyclohexanols; Endocannabinoids; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Polyunsaturated Alkamides; Potassium; Rats; Rats, Wistar; Synaptosomes | 2004 |
AM404 enhances the spontaneous release of L-glutamate in a manner sensitive to capsazepine in adult rat substantia gelatinosa neurones.
Topics: Anesthetics, Local; Animals; Arachidonic Acids; Biological Transport; Capsaicin; Drug Interactions; Endocannabinoids; Glutamic Acid; Male; Neurons; Polyunsaturated Alkamides; Rats; Receptors, Drug; Substantia Gelatinosa; Tetrodotoxin | 2004 |
Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential.
Topics: Amidohydrolases; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Capsaicin; Carrier Proteins; Cell Line, Tumor; Endocannabinoids; Female; Ganglia, Spinal; Humans; In Vitro Techniques; Indicators and Reagents; Ion Channels; Neurons; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; TRPV Cation Channels; Urinary Bladder; Urinary Incontinence | 2005 |
Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors.
Topics: Arachidonic Acids; Blood-Brain Barrier; Brain; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Modulators; Capsaicin; Cell Adhesion Molecules; Cells, Cultured; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Endothelium, Vascular; Glycerides; Humans; Ion Channels; Microcirculation; Microfilament Proteins; Phosphoproteins; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; RNA, Messenger; TRPV Cation Channels | 2004 |
Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis.
Topics: Acrolein; Animals; Arachidonic Acids; Capsaicin; Cyclophosphamide; Cystitis; Endocannabinoids; Female; Hydrolysis; Ion Channels; Pain; Polyunsaturated Alkamides; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reflex, Abnormal; TRPV Cation Channels; Urinary Bladder | 2004 |
Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro.
Topics: Animals; Arachidonic Acids; Calcium; Capsaicin; Caspase 3; Caspase Inhibitors; Caspases; Cell Death; Cells, Cultured; Cytochromes c; Dopamine; Endocannabinoids; Immunohistochemistry; Ion Channels; Ligands; Mesencephalon; Mitochondria; Nerve Tissue Proteins; Neurons; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Substantia Nigra; TRPV Cation Channels | 2005 |
AM404, an inhibitor of anandamide reuptake decreases Fos-immunoreactivity in the spinal cord of neuropathic rats after non-noxious stimulation.
Topics: Animals; Arachidonic Acids; Capsaicin; Constriction; Dose-Response Relationship, Drug; Endocannabinoids; Immunohistochemistry; Indoles; Male; Physical Stimulation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 2005 |
Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids.
Topics: Animals; Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ion Channels; Polyunsaturated Alkamides; Rats; Recombinant Proteins; Species Specificity; Temperature; TRPV Cation Channels | 2005 |
A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1.
Topics: Animals; Arachidonic Acids; Calcium Signaling; Capsaicin; Cell Line; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Endocannabinoids; Ganglia, Spinal; Humans; Hyperalgesia; Inflammation; Inflammation Mediators; Ion Channel Gating; Ion Channels; Macrophage Inflammatory Proteins; Mice; Mice, Inbred BALB C; Neurons; Polyunsaturated Alkamides; Rats; Receptors, CCR1; Receptors, Chemokine; Transfection; TRPV Cation Channels | 2005 |
Capsaicin- and anandamide-induced gastric acid secretion via vanilloid receptor type 1 (TRPV1) in rat brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA Antagonists; Gastric Acid; Gastric Mucosa; Injections, Intraventricular; Ion Channels; Male; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Statistics, Nonparametric; TRPV Cation Channels | 2005 |
Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Diterpenes; Endocannabinoids; Fluorescent Dyes; Fura-2; Ion Channels; Kinetics; Polyunsaturated Alkamides; Rats; TRPV Cation Channels | 2005 |
The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.
Topics: Animals; Apamin; Arachidonic Acids; Azepines; Barium Compounds; Biological Factors; Calcium; Cannabinoid Receptor Modulators; Capsaicin; Charybdotoxin; Chlorides; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Endocannabinoids; Endothelium, Vascular; Female; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Channels; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Vasodilation; Verapamil | 2005 |
Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling.
Topics: Adenosine Triphosphate; Aminobutyrates; Animals; Arachidonic Acids; Behavior, Animal; Bradykinin; Calcium; Calcium Channel Blockers; Capsaicin; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Endocannabinoids; Extracellular Space; Humans; Hydrogen-Ion Concentration; Magnesium Sulfate; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Microinjections; Models, Biological; Mutagenesis; Neurons; Nodose Ganglion; Oocytes; Pain; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Polyunsaturated Alkamides; Protein Kinase C; Signal Transduction; Temperature; Time Factors; Transfection; TRPV Cation Channels | 2005 |
Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation.
Topics: Adult; Arachidonic Acids; Benzylamines; Capsaicin; Endocannabinoids; Female; Forearm; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Muscle, Skeletal; Plethysmography; Polyunsaturated Alkamides; Regional Blood Flow; Skin; TRPV Cation Channels | 2005 |
Effect of olvanil and anandamide on vagal C-fiber subtypes in guinea pig lung.
Topics: Action Potentials; Animals; Arachidonic Acids; Bronchi; Capsaicin; Diterpenes; Endocannabinoids; Glomus Jugulare; Guinea Pigs; In Vitro Techniques; Lung; Male; Nerve Fibers, Unmyelinated; Nodose Ganglion; Polyunsaturated Alkamides; Temperature; Time Factors; Trachea; TRPV Cation Channels; Vagus Nerve | 2005 |
Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists.
Topics: Animals; Arachidonic Acids; Area Under Curve; Arteries; Calcium; Cannabinoids; Capsaicin; Cell Line; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Female; Fluorometry; Ganglia; Humans; Ligands; Lipids; Male; Mice; Mice, Inbred C57BL; Models, Chemical; Models, Molecular; Molecular Conformation; Neurons; Polyunsaturated Alkamides; Protein Binding; Rats; Rats, Wistar; Software; Time Factors; TRPV Cation Channels | 2005 |
Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed.
Topics: Anilides; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Capsaicin; Cinnamates; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Artery, Superior; Nitric Oxide; Nitroarginine; Perfusion; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; RNA, Messenger; TRPV Cation Channels; Vasodilation | 2005 |
Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.
Topics: Amides; Animals; Arachidonic Acids; Bronchi; Bronchoconstriction; Calcium Channel Blockers; Camphanes; Cannabinoid Receptor Agonists; Capsaicin; Electric Stimulation; Endocannabinoids; Ethanolamines; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Organ Culture Techniques; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Substance P | 2005 |
Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla.
Topics: Amidohydrolases; Analgesia; Animals; Arachidonic Acids; Cannabinoids; Capsaicin; Carrier Proteins; Cytosol; Endocannabinoids; Male; Medulla Oblongata; Mice; Microinjections; Pain Measurement; Periaqueductal Gray; Phospholipases A; Phospholipases A2; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Stress, Psychological; TRPV Cation Channels | 2005 |
VR1-mediated depressor effects during high-salt intake: role of anandamide.
Topics: Animals; Arachidonic Acids; Blood Pressure; Cannabinoid Receptor Modulators; Cannabinoids; Capsaicin; Dose-Response Relationship, Drug; Drug Combinations; Endocannabinoids; Male; Mesenteric Arteries; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Sodium, Dietary; Time Factors; TRPV Cation Channels | 2005 |
Inflammatory mediators convert anandamide into a potent activator of the vanilloid type 1 transient receptor potential receptor in nociceptive primary sensory neurons.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Bradykinin; Capsaicin; Cells, Cultured; Cobalt; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Endocannabinoids; Enzyme Inhibitors; Inflammation Mediators; Neurons, Afferent; Nociceptors; Polyunsaturated Alkamides; Protein Kinase C; Rats; Rats, Sprague-Dawley; TRPV Cation Channels; Type C Phospholipases | 2005 |
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Attention Deficit Disorder with Hyperactivity; Cannabinoid Receptor Modulators; Capsaicin; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocannabinoids; Mice; Mice, Knockout; Motor Activity; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Serotonin; Signal Transduction; TRPV Cation Channels | 2006 |
Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis.
Topics: Animals; Arachidonic Acids; Blotting, Western; Body Weight; Cannabinoid Receptor Modulators; Capsaicin; CD4-Positive T-Lymphocytes; Cell Line; Cell Proliferation; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Interactions; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Enzyme Activation; Female; Flow Cytometry; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Mice; Myelin Proteolipid Protein; Peptide Fragments; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-akt; Statistics, Nonparametric; Time Factors | 2006 |
Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arachidonic Acids; Basal Ganglia; Brain; Cannabinoid Receptor Modulators; Capsaicin; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Gene Expression; Glycerides; Male; Multiple Sclerosis; Phosphodiesterase Inhibitors; Polyunsaturated Alkamides; Rats; Rats, Inbred Lew; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Rolipram; TRPV Cation Channels | 2005 |
Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoxazines; Calcimycin; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Glutamates; Hippocampus; Male; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate | 2006 |
Phosphorylation-dependent desensitization by anandamide of vanilloid receptor-1 (TRPV1) function in rat skeletal muscle arterioles and in Chinese hamster ovary cells expressing TRPV1.
Topics: Animals; Arachidonic Acids; Arterioles; Calcineurin Inhibitors; Calcium Channel Blockers; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Endocannabinoids; Muscle, Skeletal; Phosphorylation; Polyunsaturated Alkamides; Rats; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2006 |
Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats.
Topics: Animals; Antihypertensive Agents; Arachidonic Acids; Baclofen; Benzoxazines; Bicuculline; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Spinal; Male; Morpholines; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin Gene-Related Peptide; Time Factors | 2006 |
Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats.
Topics: Amidohydrolases; Anilides; Animals; Arachidonic Acids; Body Temperature; Capsaicin; Cinnamates; Endocannabinoids; Hypothermia; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; TRPV Cation Channels | 2006 |
Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats.
Topics: Animals; Antithrombins; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Disease Models, Animal; Endocannabinoids; Endotoxins; Ganglia, Spinal; Gene Expression Regulation; Hypotension; Indoles; Indomethacin; Lung; Male; Neurons, Afferent; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Peptide Fragments; Polyunsaturated Alkamides; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; RNA, Messenger; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2006 |
Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons.
Topics: Animals; Arachidonic Acids; Benzoxazines; Blood Pressure; Capsaicin; Endocannabinoids; Male; Migraine Disorders; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Trigeminal Nerve; TRPV Cation Channels | 2007 |
Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Capsaicin; Chromatography, High Pressure Liquid; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Edema; Endocannabinoids; Formaldehyde; Ibuprofen; Lactones; Male; Mass Spectrometry; Nitrobenzenes; Pain Measurement; Peripheral Nervous System; Polyunsaturated Alkamides; Rats; Rats, Wistar; Sulfonamides; Sulfones; TRPV Cation Channels | 2006 |
Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors.
Topics: Animals; Arachidonic Acids; Bile Ducts; Blood Flow Velocity; Blood Pressure; Blotting, Western; Capsaicin; Cardiac Output; Disease Models, Animal; Endocannabinoids; Hyperemia; Indoles; Liver Circulation; Liver Cirrhosis, Biliary; Male; Mesenteric Artery, Superior; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Splanchnic Circulation; Time Factors; TRPV Cation Channels; Vascular Resistance; Vasodilation; Vasodilator Agents | 2006 |
Differential mechanisms mediating depressor and diuretic effects of anandamide.
Topics: Animals; Arachidonic Acids; Blood Pressure; Calcium Channel Blockers; Capsaicin; Diuresis; Dose-Response Relationship, Drug; Endocannabinoids; Kidney; Kidney Medulla; Male; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2006 |
Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acetamides; Animals; Anti-Ulcer Agents; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclooxygenase Inhibitors; Disease Models, Animal; Endocannabinoids; Famotidine; Ganglia, Spinal; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Male; Neurons, Afferent; Neutrophil Activation; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 2007 |
Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Calcium; Capsaicin; Carbamates; Cells, Cultured; Dopamine; Drug Interactions; Endocannabinoids; Fura-2; Furans; Ganglia, Spinal; Male; Membrane Potentials; Membrane Transport Proteins; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; TRPV Cation Channels | 2006 |
Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint.
Topics: Amidohydrolases; Analysis of Variance; Animals; Arachidonic Acids; Benzamides; Blood Vessels; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Capsaicin; Carbamates; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endocannabinoids; Flurbiprofen; Hindlimb; Indoles; Joints; Morpholines; Polyunsaturated Alkamides; Pyrazoles; Rats; Regional Blood Flow; TRPV Cation Channels; Vasodilation | 2007 |
Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans.
Topics: Administration, Topical; Animals; Arachidonic Acids; Capsaicin; Dermis; Elasticity; Endocannabinoids; Face; Female; Humans; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Polyunsaturated Alkamides; Skin | 2007 |
Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet.
Topics: Animals; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Hypertension; Male; Polyunsaturated Alkamides; Rats; Rats, Wistar; Sodium Chloride, Dietary; TRPV Cation Channels | 2007 |
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells.
Topics: Activating Transcription Factor 3; Arachidonic Acids; Calcium; Capsaicin; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cinnamates; Cyclin D1; Cyclin G2; Cyclins; Diterpenes; Dithiothreitol; Endocannabinoids; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Epithelial Cells; Eukaryotic Initiation Factor-2; Gene Expression; Humans; Lung; Phosphorylation; Polyunsaturated Alkamides; Thapsigargin; Thiourea; Transcription Factor CHOP; Transfection; TRPV Cation Channels | 2007 |
Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells.
Topics: Arachidonic Acids; Capsaicin; CD28 Antigens; CD3 Complex; CD36 Antigens; Endocannabinoids; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Oligonucleotide Array Sequence Analysis; Polyunsaturated Alkamides; Up-Regulation | 2007 |
Activation of recombinant human TRPV1 receptors expressed in SH-SY5Y human neuroblastoma cells increases [Ca(2+)](i), initiates neurotransmitter release and promotes delayed cell death.
Topics: Arachidonic Acids; Calcium; Calcium Signaling; Capsaicin; Cell Culture Techniques; Cell Death; Cell Line, Tumor; Cell Proliferation; Diterpenes; Dopamine; Endocannabinoids; Humans; Models, Biological; Neuroblastoma; Neurons; Norepinephrine; Polyunsaturated Alkamides; Recombinant Proteins; Synaptic Transmission; Transfection; TRPV Cation Channels; Up-Regulation | 2007 |
Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret.
Topics: Acrylamides; Animals; Antiemetics; Arachidonic Acids; Area Postrema; Autonomic Pathways; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Cannabinoids; Capsaicin; Dopamine; Emetics; Endocannabinoids; Ferrets; Male; Mice; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Solitary Nucleus; TRPV Cation Channels; Vagus Nerve; Vomiting | 2007 |
AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain.
Topics: Animals; Arachidonic Acids; Capsaicin; Endocannabinoids; Immunohistochemistry; Indoles; Inflammation; Male; Pain; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Spinal Cord; TRPV Cation Channels | 2007 |
The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level.
Topics: Analgesics; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Hyperalgesia; Injections, Spinal; Male; Polyunsaturated Alkamides; Rats; Rats, Wistar; Spinal Cord; TRPV Cation Channels | 2008 |
Effects of anandamide and noxious heat on intracellular calcium concentration in nociceptive drg neurons of rats.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; Capsaicin; Chelating Agents; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Egtazic Acid; Endocannabinoids; Extracellular Fluid; Ganglia, Spinal; Hot Temperature; Neurons; Physical Stimulation; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; TRPV Cation Channels | 2007 |
The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; TRPV Cation Channels; Urinary Bladder | 2007 |
Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Capsaicin; Carbamates; Cell Count; Chromatography, High Pressure Liquid; Endocannabinoids; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Hydrolysis; Intraocular Pressure; Male; Ocular Hypertension; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Reperfusion Injury; Retinal Diseases; Retinal Ganglion Cells; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Thy-1 Antigens; TRPV Cation Channels | 2007 |
The anandamide transport inhibitor AM404 reduces ethanol self-administration.
Topics: Alcohol Drinking; Animals; Arachidonic Acids; Capsaicin; Central Nervous System Depressants; Conditioning, Operant; Depression, Chemical; Endocannabinoids; Ethanol; Extinction, Psychological; Hypothermia; Male; Motor Activity; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reinforcement, Psychology; Saccharin; Self Administration; TRPV Cation Channels | 2007 |
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
Topics: Animals; Aorta, Abdominal; Apamin; Arachidonic Acids; Benzamides; Calcitonin Gene-Related Peptide; Camphanes; Cannabinoid Receptor Modulators; Capsaicin; Carbamates; Charybdotoxin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Isoindoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sulfonamides; Vasodilation | 2007 |
Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors.
Topics: Amidohydrolases; Animals; Antiparkinson Agents; Arachidonic Acids; Basal Ganglia; Benzamides; Benzoxazines; Cannabinoids; Capsaicin; Carbamates; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Endocannabinoids; Levodopa; Male; Morpholines; Naphthalenes; Oxidopamine; Parkinson Disease, Secondary; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; TRPV Cation Channels | 2007 |
Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene.
Topics: Arachidonic Acids; Biotin; Blotting, Western; Calcium; Calcium Channel Blockers; Capsaicin; Cell Line, Tumor; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Endocannabinoids; Gene Expression; Genetic Variation; Humans; Image Processing, Computer-Assisted; Nuclease Protection Assays; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Polyunsaturated Alkamides; Transfection; TRPV Cation Channels | 2007 |
The group IV afferent neuron expresses multiple receptor alterations in cardiomyopathyic rats: evidence at the cannabinoid CB1 receptor.
Topics: Animals; Apoptosis; Arachidonic Acids; Blood Pressure; Cannabinoid Receptor Modulators; Capsaicin; Cardiomyopathy, Dilated; Disease Models, Animal; Endocannabinoids; Ganglia, Spinal; Male; Neurons, Afferent; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sensory System Agents; TRPV Cation Channels; Ventricular Dysfunction, Left | 2008 |
Elevated temperatures alter TRPV1 agonist-evoked excitability of dorsal root ganglion neurons.
Topics: Action Potentials; Animals; Arachidonic Acids; Capsaicin; Endocannabinoids; Ganglia, Spinal; Male; Phosphorylation; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Temperature; TRPV Cation Channels | 2008 |
TRPV1 channels facilitate glutamate transmission in the striatum.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Corpus Striatum; Endocannabinoids; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Patch-Clamp Techniques; Polyunsaturated Alkamides; Protein Kinase C; Sensory System Agents; Synaptic Transmission; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2009 |
Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat.
Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Capsaicin; Corticosterone; Defecation; Electromyography; Endocannabinoids; Ganglia, Spinal; Hyperalgesia; Immunohistochemistry; Intestinal Mucosa; Male; Microscopy, Fluorescence; Models, Animal; Morpholines; Naphthalenes; Pain Threshold; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Spectrum Analysis; Stress, Psychological; TRPV Cation Channels | 2009 |
The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption.
Topics: Acid Phosphatase; Amidohydrolases; Animals; Arachidonic Acids; Bone and Bones; Bone Resorption; Calcium; Cannabinoid Receptor Modulators; Capsaicin; Cathepsin K; Cathepsins; Cell Differentiation; Cells, Cultured; Endocannabinoids; Humans; Isoenzymes; Mice; Osteoclasts; Osteogenesis; Phospholipase D; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Tartrate-Resistant Acid Phosphatase; TRPV Cation Channels | 2009 |
Effects of hypertension on vasorelaxation to endocannabinoids in vitro.
Topics: Animals; Aorta; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Carbachol; Endocannabinoids; Endothelium; Hypertension; Male; Mesenteric Arteries; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Polyunsaturated Alkamides; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; TRPV Cation Channels; Vasodilation | 2009 |
N-acyldopamines control striatal input terminals via novel ligand-gated cation channels.
Topics: Animals; Arachidonic Acids; Boron Compounds; Capsaicin; Cations; Corpus Striatum; Dopamine; Endocannabinoids; Glutamic Acid; Ion Channels; Ligands; Male; Mice; Mice, Mutant Strains; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes; TRPV Cation Channels | 2009 |
Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors.
Topics: Adenosine; Animals; Apnea; Arachidonic Acids; Blood Pressure; Capsaicin; Endocannabinoids; Heart Rate; Infusions, Intravenous; Lung; Male; Morpholines; Neurons, Afferent; Physical Stimulation; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; TRPV Cation Channels; Vagus Nerve | 2009 |
TRPV1-mediated itch in seasonal allergic rhinitis.
Topics: Acrolein; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Arachidonic Acids; Calcium Channel Blockers; Calcium Channels; Capsaicin; Endocannabinoids; Humans; Menthol; Mustard Plant; Nasal Provocation Tests; Nerve Tissue Proteins; Plant Oils; Polyunsaturated Alkamides; Pruritus; Rhinitis, Allergic, Seasonal; Sensory System Agents; Severity of Illness Index; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels | 2009 |
Excitation of cutaneous C nociceptors by intraplantar administration of anandamide.
Topics: Action Potentials; Anilides; Animals; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Cinnamates; Dose-Response Relationship, Drug; Endocannabinoids; Hindlimb; Hot Temperature; Male; Nociceptors; Pain; Pain Measurement; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Skin; Tibial Nerve; TRPV Cation Channels | 2009 |
A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells.
Topics: Amino Acids; Anilides; Animals; Arachidonic Acids; Capsaicin; Cinnamates; Endocannabinoids; Excitatory Amino Acid Antagonists; Glutamic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Polyunsaturated Alkamides; Propionates; Receptors, Metabotropic Glutamate; Retinal Bipolar Cells; Ruthenium Red; Synaptic Transmission; Transient Receptor Potential Channels; TRPM Cation Channels; TRPV Cation Channels; Xanthenes | 2009 |
Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons.
Topics: Animals; Arachidonic Acids; Bradykinin; Capsaicin; Cations, Divalent; Cells, Cultured; Cobalt; Dinoprostone; Dronabinol; Endocannabinoids; Female; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; TRPV Cation Channels | 2009 |
Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability.
Topics: Acrosome Reaction; Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Cricetinae; Endocannabinoids; Humans; Infertility, Male; Male; Phospholipase D; Polyunsaturated Alkamides; Progesterone; Receptor, Cannabinoid, CB1; Spermatozoa; TRPV Cation Channels | 2009 |
Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids.
Topics: Analgesics; Analysis of Variance; Animals; Anxiety; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Male; Microinjections; Morpholines; Naphthalenes; Periaqueductal Gray; Polyunsaturated Alkamides; Rats; Rats, Wistar; Time Factors; TRPV Cation Channels | 2009 |
Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Dentate Gyrus; Disease Models, Animal; Drug Design; Endocannabinoids; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; Male; Mice; Mice, Inbred Strains; Mossy Fibers, Hippocampal; Muscarinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pilocarpine; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Sensory System Agents; Synaptic Transmission; TRPV Cation Channels | 2010 |
Transient receptor potential vanilloid 1 channels control acetylcholine/2-arachidonoylglicerol coupling in the striatum.
Topics: Acetylcholine; Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Capsaicin; Carbamates; Corpus Striatum; Endocannabinoids; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glycerides; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Agonists; Neural Inhibition; Organ Culture Techniques; Polyunsaturated Alkamides; Receptor, Metabotropic Glutamate 5; Receptor, Muscarinic M1; Receptors, Metabotropic Glutamate; Sensory System Agents; Synaptic Transmission; TRPV Cation Channels | 2010 |
Pharmacology of capsaicin-, anandamide-, and N-arachidonoyl-dopamine-evoked cell death in a homogeneous transient receptor potential vanilloid subtype 1 receptor population.
Topics: Apoptosis; Arachidonic Acids; Capsaicin; Dopamine; Dose-Response Relationship, Drug; Endocannabinoids; Humans; Neurons; Polyunsaturated Alkamides; TRPV Cation Channels; Tumor Cells, Cultured | 2010 |
The endogenous cannabinoid anandamide inhibits transient receptor potential vanilloid type 1 receptor-mediated currents in rat cultured primary sensory neurons.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Endocannabinoids; Evoked Potentials; Female; Ganglia, Spinal; Isoquinolines; Patch-Clamp Techniques; Phosphorylation; Polyunsaturated Alkamides; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; Sensory System Agents; Sulfonamides; TRPV Cation Channels | 2010 |
Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity.
Topics: Animals; Aorta, Thoracic; Arachidonic Acids; Caffeine; Capsaicin; Chloride Channels; Endocannabinoids; Endothelium, Vascular; Ethanolamines; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Nitric Oxide; Oleic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; Vasodilation | 2010 |
Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators.
Topics: Animals; Arachidonic Acids; Bradykinin; Capsaicin; Cells, Cultured; Cobalt; Dinoprostone; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Inflammation Mediators; Male; Nerve Growth Factor; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; TRPV Cation Channels | 2010 |
Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Periaqueductal Gray; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Synaptic Transmission; TRPV Cation Channels | 2011 |
N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity.
Topics: Administration, Topical; Analgesics; Animals; Arachidonic Acids; Calcium; Capsaicin; Cell Line; Endocannabinoids; Eye; Humans; Male; Mice; Pain; Polyunsaturated Alkamides; TRPV Cation Channels | 2011 |
Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1.
Topics: Amygdala; Anesthesia; Anesthetics; Animals; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Learning; Long-Term Potentiation; Mice; Mice, Knockout; Nitric Oxide Synthase; Polyunsaturated Alkamides; TRPV Cation Channels | 2011 |
The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Body Temperature Regulation; Brain; Camphanes; Capsaicin; Disease Models, Animal; Diterpenes; Endocannabinoids; Female; Hypothermia; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Lipopolysaccharides; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Signal Transduction; Sulfonamides; Time Factors; TRPV Cation Channels | 2011 |
Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Hot Temperature; Male; Mice; Mice, Knockout; Polyunsaturated Alkamides; Psychotropic Drugs; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Sensory System Agents; Skin; TRPV Cation Channels | 2011 |
Painful pathways induced by TLR stimulation of dorsal root ganglion neurons.
Topics: Aminoquinolines; Anilides; Animals; Arachidonic Acids; Blotting, Western; Calcium; Capsaicin; Cells, Cultured; Cinnamates; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Endocannabinoids; Ganglia, Spinal; Humans; Imidazoles; Mice; Microscopy, Confocal; Neurons; Pain; Poly I-C; Polyunsaturated Alkamides; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 9; Toll-Like Receptors; TRPV Cation Channels | 2011 |
Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors.
Topics: Animals; Antidepressive Agents; Arachidonic Acids; Capsaicin; Depression; Dopamine; Endocannabinoids; Hindlimb Suspension; Ligands; Male; Mice; Mice, Inbred ICR; Nicotine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Stress, Psychological; Swimming; TRPV Cation Channels | 2011 |
TRPV1, TRPA1, and CB1 in the isolated vagus nerve--axonal chemosensitivity and control of neuropeptide release.
Topics: Animals; Arachidonic Acids; Axons; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; Capsaicin; Endocannabinoids; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Neuropeptides; Plant Oils; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sensory System Agents; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels; Vagus Nerve | 2011 |
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Arterioles; Benzamides; Benzoxazines; Blood Pressure; Caproates; Capsaicin; Carbamates; Dose-Response Relationship, Drug; Endocannabinoids; Flavanones; Immunohistochemistry; In Vitro Techniques; Indomethacin; Morpholines; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Polyunsaturated Alkamides; Rats | 2012 |
Agonist-dependent potentiation of vanilloid receptor transient receptor potential vanilloid type 1 function by stilbene derivatives.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Arachidonic Acids; Calcium; Capsaicin; Cells, Cultured; Endocannabinoids; Humans; Hydrogen-Ion Concentration; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Stilbenes; TRPV Cation Channels | 2012 |
Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amidohydrolases; Animals; Anisoles; Apamin; Arachidonic Acids; Benzamides; Benzyl Compounds; Cannabinoid Receptor Antagonists; Capsaicin; Carbamates; Charybdotoxin; Cyclohexanes; Endocannabinoids; Endothelium, Vascular; Imidazoles; Indoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Epoprostenol; Tetraethylammonium; TRPV Cation Channels; Vasodilation | 2012 |
TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Cannabinoid Receptor Antagonists; Capsaicin; Cyclic AMP; Diterpenes; Endocannabinoids; Glycerides; Hydrogen-Ion Concentration; Odontoblasts; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Sodium-Calcium Exchanger; Thiourea; TRPV Cation Channels | 2012 |
Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1.
Topics: Aging; Amides; Amidohydrolases; Animals; Antineoplastic Agents; Apoptosis; Arachidonic Acids; Brain; Brain Neoplasms; Capsaicin; Cell Movement; Culture Media, Conditioned; Dopamine; Endocannabinoids; Ethanolamines; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Neoplasm Proteins; Neural Stem Cells; Oleic Acids; Palmitic Acids; Polyunsaturated Alkamides; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; TRPV Cation Channels; Tumor Cells, Cultured | 2012 |
Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats.
Topics: Analgesics; Animals; Arachidonic Acids; Behavior, Animal; Capsaicin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Endocannabinoids; Formaldehyde; Hyperalgesia; Indoles; Male; Pain Measurement; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid | 2012 |
Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Male; Maze Learning; Periaqueductal Gray; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; TRPV Cation Channels | 2013 |
The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves.
Topics: Animals; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Cyclooxygenase Inhibitors; Endocannabinoids; Female; Guinea Pigs; Indomethacin; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Polyunsaturated Alkamides; Prostaglandins; Sensory Receptor Cells; Sensory System Agents; TRPV Cation Channels | 2013 |
Modulation by 17β-estradiol of anandamide vasorelaxation in normotensive and hypertensive rats: a role for TRPV1 but not fatty acid amide hydrolase.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Estradiol; Female; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Polyunsaturated Alkamides; Rats; Rats, Wistar; Resorcinols; TRPV Cation Channels; Vasodilation | 2013 |
Transient receptor potential vanilloid 1 is expressed in human cytotrophoblasts: induction of cell apoptosis and impairment of syncytialization.
Topics: Apoptosis; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Cell Differentiation; Cell Survival; Endocannabinoids; Female; Humans; Polyunsaturated Alkamides; Pregnancy; Trophoblasts; TRPV Cation Channels | 2014 |
A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis.
Topics: Activating Transcription Factor 3; Amidohydrolases; Anilides; Animals; Arachidonic Acids; Benzamides; Capsaicin; Carbamates; Cinnamates; Disease Models, Animal; Endocannabinoids; Ganglia, Spinal; Gene Expression; Hyperalgesia; Inflammation; Interleukin-6; Lumbar Vertebrae; Male; Osteoarthritis; Pain; Pain Management; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; TRPV Cation Channels | 2015 |
Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS.
Topics: Allergens; Amides; Animals; Arachidonic Acids; Asthma; Brain Stem; Capsaicin; Endocannabinoids; Ethanolamines; Glycerides; Humans; Neuroglia; Neurons; Palmitic Acids; Polyunsaturated Alkamides; Propionates; Rats; Receptors, Glutamate; Respiratory Hypersensitivity; Solitary Nucleus | 2015 |
The endocannabinoid, endovanilloid and nitrergic systems could interact in the rat dorsolateral periaqueductal gray matter to control anxiety-like behaviors.
Topics: Animals; Anxiety; Arachidonic Acids; Cannabinoid Receptor Agonists; Capsaicin; Cyclic N-Oxides; Disease Models, Animal; Drinking; Drug Interactions; Endocannabinoids; Free Radical Scavengers; Imidazoles; Male; Maze Learning; Microinjections; Nitric Oxide; Periaqueductal Gray; Polyunsaturated Alkamides; Rats; Rats, Wistar; Reaction Time; TRPV Cation Channels | 2015 |
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy.
Topics: Amides; Amidohydrolases; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Capsaicin; Chronic Pain; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Endocannabinoids; Ethanolamines; Formaldehyde; Male; Medulla Oblongata; Nociceptive Pain; Oleic Acids; Palmitic Acids; Polyunsaturated Alkamides; Rats, Wistar; RNA, Messenger; TRPV Cation Channels | 2016 |
Endovanilloids are potential activators of the trigeminovascular nocisensor complex.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Agonists; Capsaicin; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Dura Mater; Endocannabinoids; Enzyme-Linked Immunosorbent Assay; Laser-Doppler Flowmetry; Nociceptors; Peptide Fragments; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Calcitonin Gene-Related Peptide; Regional Blood Flow; Trigeminal Nerve; TRPV Cation Channels | 2016 |
Co-administration of cannabidiol and capsazepine reduces L-DOPA-induced dyskinesia in mice: Possible mechanism of action.
Topics: Animals; Anti-Dyskinesia Agents; Arachidonic Acids; Brain; Cannabidiol; Capsaicin; Cyclooxygenase 2; Dyskinesia, Drug-Induced; Endocannabinoids; Extracellular Signal-Regulated MAP Kinases; Histones; Levodopa; Male; Mice, Inbred C57BL; NF-kappa B; Oxidopamine; Parkinsonian Disorders; Polyunsaturated Alkamides; PPAR gamma; Receptor, Cannabinoid, CB1; TRPV Cation Channels; Tyrosine 3-Monooxygenase | 2016 |
Mitogen-Activated Protein Kinase and Intracellular Polyamine Signaling Is Involved in TRPV1 Activation-Induced Cardiac Hypertrophy.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Down-Regulation; Endocannabinoids; Enzyme Inhibitors; Ligation; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Polyamines; Polyunsaturated Alkamides; Rats, Wistar; RNA, Small Interfering; Signal Transduction; TRPV Cation Channels | 2016 |
Inhibitions of anandamide transport and FAAH synthesis decrease apoptosis and oxidative stress through inhibition of TRPV1 channel in an in vitro seizure model.
Topics: Amidohydrolases; Animals; Apoptosis; Arachidonic Acids; Calcium Signaling; Capsaicin; Cell Line, Tumor; Disease Models, Animal; Endocannabinoids; Hippocampus; Humans; Male; Oxidative Stress; Polyunsaturated Alkamides; Rats; Rats, Wistar; Seizures; TRPV Cation Channels | 2019 |
The investigation of allosteric regulation mechanism of analgesic effect using SD rat taste bud tissue biosensor.
Topics: Alginates; Allosteric Regulation; Analgesics; Animals; Arachidonic Acids; Biosensing Techniques; Body Temperature; Capsaicin; Cross-Linking Reagents; Electrochemical Techniques; Endocannabinoids; Fever; Pain; Polyunsaturated Alkamides; Rats, Sprague-Dawley; Starch; Taste Buds; TRPV Cation Channels | 2019 |
Molecular and functional insights into Transient Receptor Potential Vanilloid 1 (TRPV1) in bull spermatozoa.
Topics: Acrosome Reaction; Animals; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Cattle; Endocannabinoids; Male; Polyunsaturated Alkamides; Sperm Capacitation; Sperm Motility; Spermatozoa; TRPV Cation Channels | 2019 |
Antiallodynic effect of PhAR-DBH-Me involves cannabinoid and TRPV1 receptors.
Topics: Animals; Antineoplastic Agents; Arachidonic Acids; Azabicyclo Compounds; Cannabinoid Receptor Antagonists; Capsaicin; Cisplatin; Endocannabinoids; Female; Hyperalgesia; Injections, Intraperitoneal; Ligation; Models, Animal; Neuralgia; Oleic Acids; Polyunsaturated Alkamides; Rats; Rats, Wistar; Spinal Nerves; TRPV Cation Channels; Vagus Nerve Stimulation | 2020 |
The Endocannabinoid System in the Mediterranean Mussel
Topics: Amino Acid Sequence; Animals; Arachidonic Acids; Capsaicin; Endocannabinoids; Hemocytes; Mytilus; Phagocytosis; Phylogeny; Polyunsaturated Alkamides; Receptors, Cannabinoid; RNA, Messenger; TRPV Cation Channels | 2021 |
Dual effects of anandamide in the antiepileptic activity of diazepam in pentylenetetrazole-induced seizures in mice.
Topics: Animals; Anticonvulsants; Capsaicin; Diazepam; Endocannabinoids; Mice; Pentylenetetrazole; Polyunsaturated Alkamides; Seizures; TRPV Cation Channels | 2022 |
Endocannabinoids, anandamide and 2-AG, regulate mechanosensitivity of mucosal afferents in the Guinea pig bladder.
Topics: Animals; Capsaicin; Endocannabinoids; Guinea Pigs; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Urinary Bladder | 2023 |