capsaicin and allyl isothiocyanate

capsaicin has been researched along with allyl isothiocyanate in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (5.66)18.2507
2000's14 (26.42)29.6817
2010's33 (62.26)24.3611
2020's3 (5.66)2.80

Authors

AuthorsStudies
Nilius, B; Owsianik, G; Talavera, K; Voets, T1
De Petrocellis, L; Di Marzo, V; Morera, E; Morera, L; Moriello, AS; Nalli, M; Ortar, G1
Horie, S; Takayama, H; Terada, Y; Tominaga, M; Uchida, K; Watanabe, T1
Appendino, G; Caprioglio, D; De Petrocellis, L; Del Prete, D; Di Marzo, V; Minassi, A; Schiano-Moriello, A1
Dai, Y; Kogure, Y; Mabuchi, M; Nakao, S; Noguchi, K; Shimizu, T; Tanaka, A; Wang, S1
Maggi, CA; Meli, A; Patacchini, R1
Azizan, A; Blevins, RD1
Matui, T; Yoshii, K1
Andrade, EL; André, E; Calixto, JB; Ferreira, J1
Iizuka, H; Imai, Y; Kurohane, K; Maruyama, T; Matsuda, T; Shiba, T; Tobisawa, Y1
Matsuda, H; Nagatomo, A; Ochi, M; Yoshikawa, M1
Horie, S; Matsumoto, K; Nakamura, T; Penuelas, A; Tashima, K; Tsuchiya, S; Yano, S1
Endo, T; Hayashi, S; Kubo, Y; Nakamura, E; Takeuchi, K1
Araki, I; Du, S; Nomura, T; Takeda, M; Yoshiyama, M1
Andrade, EL; Calixto, JB; Ferreira, J; Luiz, AP1
Andersson, KE; Gratzke, C; Hedlund, P; Sigl, K; Stief, C; Streng, T; Waldkirch, E1
Iwasaki, Y; Kobata, K; Tanabe, M; Watanabe, T1
Bang, SI; Jin, YH; Sun, B1
Fujita, T; Jiang, CY; Kumamoto, E; Liu, T; Nakatsuka, T; Piao, LH; Yue, HY1
Andrè, E; Baraldi, PG; Gatti, R; Geppetti, P; Patacchini, R; Preti, D; Trevisani, M1
Cahusac, PM1
Andersson, KE; Gratzke, C; Hedlund, P; Stief, C; Streng, T; Weinhold, P1
Furue, H; Imoto, K; Katafuchi, T; Mizuguchi-Takase, H; Pickering, AE; Rashid, MH; Uta, D; Yoshimura, M1
Bock, E; Holzer, P; Mitrovic, M; Pabst, MA; Shahbazian, A1
Gu, J; Sarria, I1
Fushiki, T; Shintaku, K; Suzuki, Y; Tominaga, M; Uchida, K; Watanabe, T; Yazawa, S; Zhou, Y1
Isami, K; Kaneko, S; Nakagawa, T; Nakamura, S; Shirakawa, H; Zhao, M1
Kaneko, A; Kono, T; Ohbuchi, K; Ohno, N; Omiya, Y; Yamamoto, M1
Dai, Y; Kogure, Y; Noguchi, K; Wang, S; Yamamoto, S; Yu, L1
Bartho, L; Benko, R; Nordtveit, E; Szombati, V1
Mutoh, T; Taki, Y; Tsubone, H1
Alpizar, YA; Boonen, B; Everaerts, W; Gees, M; Janssens, A; Nilius, B; Owsianik, G; Sanchez, A; Segal, A; Talavera, K; Voets, T; Xue, F1
Antunes, E; Ferreira, J; Hoffmeister, C; Matheus, FC; Mello, GC; Oliveira, SM; Prediger, RD; Rossato, MF; Silva, CR; Trevisan, G1
Suzuki, Y; Tominaga, M; Uchida, K; Zhou, Y1
Chung, G; Im, ST; Jung, SJ; Kim, YH; Oh, SB; Rhyu, MR1
Di Silvio, L; Duggal, AK; Egbuniwe, O; Grant, AD; Grover, S; Mavroudis, A; Renton, T; Yazdi, M1
Khosravi, M; Lee, LY; Lin, RL; Lin, YJ; Ruan, T1
Harano, N; Hitomi, S; Inenaga, K; Kuramitsu, S; Matoba, M; Matsuo, K; Miyano, K; Ono, K; Ota, Y; Seta, Y; Uezono, Y; Yamaguchi, K1
Cianchetti, C; Luvisetto, S; Vacca, V1
Matoba, M; Minami, K; Miyano, K; Murakami, S; Ohbuchi, K; Shiraishi, S; Uezono, Y; Yamaguchi, T; Yamamoto, M; Yokoyama, T1
Filipek, B; Sałat, K1
Kikuchi, D; Miyachi, T; Nagao, M; Naitoh, T; Sasaki, H; Shibata, C; Someya, S; Tanaka, N; Unno, M1
Aguilera, M; De Alba, J; Domènech, A; Fernández-Blanco, JA; Miralpeix, M; Prats, N; Tarrasón, G1
Breslin, JW; Dean, JB; Hadley, SH; Hooper, JS; Morris, KF; Taylor-Clark, TE1
Bartho, L; Bencsik, T; Dekany, A; Kelemen, D; Papp, R; Sandor, Z1
Alpizar, YA; Boeckxstaens, G; Callebaut, I; Hellings, PW; Kortekaas Krohn, I; Steelant, B; Talavera, K; Van Gerven, L; Vermeulen, F; Wouters, M1
Gratzke, C; Hedlund, P; Hennenberg, M; Stief, CG; Strittmatter, F; Weinhold, P1
Jankowska, M; Kletkiewicz, H; Maliszewska, J; Rogalska, J; Stankiewicz, M1
Barker, AJ; Bennett, NC; Debus, KY; Eigenbrod, O; Hart, DW; Katandukila, JV; Lewin, GR; Lutermann, H; Mgode, G; Omerbašić, D; Park, TJ; Reznick, J; Sánchez-Carranza, O; Zhong, W1
Chen, Q; Chung, KF; Lai, K; Long, L; Luo, W; Tian, J; Xie, J; Yao, H; Yi, F; Yu, X; Zhong, N1
Akiyama, T; Carstens, E; Carstens, MI; Curtis, E1
Horie, S; Namiki, T; Ohashi, N; Tashima, K1
Brown, AJH; Cox, HM; Evans, C; Howells, K; Suzuki, R1

Reviews

1 review(s) available for capsaicin and allyl isothiocyanate

ArticleYear
Sensing with TRP channels.
    Nature chemical biology, 2005, Volume: 1, Issue:2

    Topics: Animals; Humans; Ligands; Models, Biological; Phylogeny; Temperature; Transient Receptor Potential Channels

2005

Trials

2 trial(s) available for capsaicin and allyl isothiocyanate

ArticleYear
Enhanced chemosensory sensitivity in patients with idiopathic rhinitis and its reversal by nasal capsaicin treatment.
    The Journal of allergy and clinical immunology, 2017, Volume: 140, Issue:2

    Topics: Administration, Intranasal; Adult; Capsaicin; Double-Blind Method; Female; Humans; Isothiocyanates; Male; Middle Aged; Nasal Mucosa; Nerve Growth Factor; Rhinitis; RNA, Messenger; Transient Receptor Potential Channels; Ubiquitin Thiolesterase; Young Adult

2017
Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough.
    Respiratory research, 2019, Jun-06, Volume: 20, Issue:1

    Topics: Adult; Capsaicin; Chronic Disease; Cough; Female; Humans; Isothiocyanates; Male; Middle Aged; Sensory System Agents; TRPA1 Cation Channel; TRPV Cation Channels

2019

Other Studies

50 other study(ies) available for capsaicin and allyl isothiocyanate

ArticleYear
Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators.
    Bioorganic & medicinal chemistry letters, 2012, Feb-15, Volume: 22, Issue:4

    Topics: Calcium Channels; Catechols; Fatty Alcohols; Humans; Inhibitory Concentration 50; Molecular Structure; Nerve Tissue Proteins; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2012
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.
    Journal of natural products, 2014, Feb-28, Volume: 77, Issue:2

    Topics: Africa; Alkaloids; Calcium; Capsaicin; Humans; Ibogaine; Menthol; Molecular Structure; Plant Bark; Pyrimidinones; Transient Receptor Potential Channels; Trees; TRPV Cation Channels; Voacanga

2014
Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands.
    Bioorganic & medicinal chemistry letters, 2015, Mar-01, Volume: 25, Issue:5

    Topics: Calcium Channels; Capsaicin; Drug Discovery; HEK293 Cells; Humans; Ligands; Nerve Tissue Proteins; Sensory System Agents; Structure-Activity Relationship; Tetrazoles; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2015
Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor.
    Bioorganic & medicinal chemistry letters, 2017, 07-15, Volume: 27, Issue:14

    Topics: Analgesics; Animals; Calcium Channels; Ganglia, Spinal; HEK293 Cells; Humans; Inhibitory Concentration 50; Nerve Tissue Proteins; Pain; Patch-Clamp Techniques; Rats; Resveratrol; Stilbenes; Transient Receptor Potential Channels; TRPA1 Cation Channel

2017
Capsaicin-like activity of some natural pungent substances on peripheral endings of visceral primary afferents.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:1

    Topics: Alkaloids; Animals; Benzodioxoles; Capsaicin; Curcumin; Eugenol; In Vitro Techniques; Isothiocyanates; Male; Muscle Contraction; Mustard Plant; Nerve Endings; Neurons, Afferent; Piperidines; Plant Extracts; Plant Oils; Polyunsaturated Alkamides; Rats; Rats, Inbred Strains; Ruthenium Red; Tetrodotoxin; Thiocyanates

1990
Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay.
    Archives of environmental contamination and toxicology, 1995, Volume: 28, Issue:2

    Topics: Acrolein; Antimutagenic Agents; Camphanes; Capsaicin; Eugenol; Flavoring Agents; Food Preservatives; Isothiocyanates; Mutagenesis; Mutagenicity Tests; Spices; Thymol

1995
Taste responses of bullfrog to pungent stimuli.
    Brain research, 1994, Feb-21, Volume: 637, Issue:1-2

    Topics: Adaptation, Physiological; Alkaloids; Animals; Benzodioxoles; Capsaicin; Chemoreceptor Cells; Electrophysiology; Glossopharyngeal Nerve; In Vitro Techniques; Isothiocyanates; Neurons, Afferent; Piperidines; Polyunsaturated Alkamides; Rana catesbeiana; Regional Blood Flow; Sensory Thresholds; Stimulation, Chemical; Taste; Tongue

1994
Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder.
    Biochemical pharmacology, 2006, Jun-28, Volume: 72, Issue:1

    Topics: Acrolein; Anilides; Animals; Ankyrins; Binding Sites; Calcium Channels; Capsaicin; Cinnamates; Diterpenes; Dose-Response Relationship, Drug; Drug Antagonism; In Vitro Techniques; Isothiocyanates; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Ruthenium Red; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels; Urinary Bladder

2006
Influence of local treatments with capsaicin or allyl isothiocyanate in the sensitization phase of a fluorescein-isothiocyanate-induced contact sensitivity model.
    International archives of allergy and immunology, 2007, Volume: 143, Issue:2

    Topics: Adoptive Transfer; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Chemotaxis, Leukocyte; Cytokines; Dermatitis, Contact; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Isothiocyanates; Mice; Mice, Inbred BALB C; Neurons, Afferent; Transient Receptor Potential Channels; TRPA1 Cation Channel

2007
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.
    European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3

    Topics: Alkaloids; Ammonia; Animals; Armoracia; Aspirin; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Food Preservatives; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isothiocyanates; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Rats; Rats, Sprague-Dawley; Ruthenium Red; Structure-Activity Relationship

2007
Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.
    European journal of pharmacology, 2007, Dec-08, Volume: 576, Issue:1-3

    Topics: Animals; Capsaicin; Disulfides; Gastrointestinal Motility; In Vitro Techniques; Intestines; Isothiocyanates; Male; Menthol; Mice; Pyrimidinones; RNA, Messenger; Sulfinic Acids; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2007
Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer.
    Inflammopharmacology, 2007, Volume: 15, Issue:5

    Topics: Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Cell Line; Epithelial Cells; Gastric Mucosa; Isothiocyanates; Menthol; Pyrimidinones; Rats; Temperature; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels; TRPV Cation Channels; Wound Healing

2007
Transient receptor potential channel A1 involved in sensory transduction of rat urinary bladder through C-fiber pathway.
    Urology, 2007, Volume: 70, Issue:4

    Topics: Acrolein; Afferent Pathways; Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Female; Ganglia, Spinal; Isothiocyanates; Nerve Fibers, Unmyelinated; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensation; Sensory System Agents; TRPA1 Cation Channel; TRPC Cation Channels; Urinary Bladder; Urodynamics

2007
Pronociceptive response elicited by TRPA1 receptor activation in mice.
    Neuroscience, 2008, Mar-18, Volume: 152, Issue:2

    Topics: Analgesics; Anilides; Animals; Behavior, Animal; Capsaicin; Cinnamates; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Isothiocyanates; Male; Mice; Pain; Pain Measurement; Ruthenium Red; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel

2008
Transient receptor potential A1 (TRPA1) activity in the human urethra--evidence for a functional role for TRPA1 in the outflow region.
    European urology, 2009, Volume: 55, Issue:3

    Topics: Acrolein; Capsaicin; Female; Humans; In Vitro Techniques; Isothiocyanates; Male; Middle Aged; Sensory System Agents; Sulfides; TRPC Cation Channels; Urethra

2009
TRPA1 agonists--allyl isothiocyanate and cinnamaldehyde--induce adrenaline secretion.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:10

    Topics: Acrolein; Adrenal Glands; Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Cholinergic Antagonists; Epinephrine; Isothiocyanates; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; TRPA1 Cation Channel; TRPC Cation Channels

2008
Transient receptor potential A1 increase glutamate release on brain stem neurons.
    Neuroreport, 2009, Jul-15, Volume: 20, Issue:11

    Topics: Animals; Ankyrins; Cadmium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Capsaicin; Cells, Cultured; Excitatory Postsynaptic Potentials; Glutamic Acid; Isothiocyanates; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Ruthenium Red; Solitary Nucleus; Tetrodotoxin; TRPA1 Cation Channel; TRPC Cation Channels

2009
Effect of resiniferatoxin on glutamatergic spontaneous excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord.
    Neuroscience, 2009, Dec-29, Volume: 164, Issue:4

    Topics: Animals; Capsaicin; Diterpenes; Glutamic Acid; In Vitro Techniques; Isothiocyanates; Male; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synaptic Transmission; TRPV Cation Channels

2009
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents.
    British journal of pharmacology, 2009, Volume: 158, Issue:6

    Topics: Acrolein; Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Drug Delivery Systems; Guinea Pigs; Isothiocyanates; Male; Oxidative Stress; Smoke; Transient Receptor Potential Channels

2009
Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.
    Journal of the peripheral nervous system : JPNS, 2009, Volume: 14, Issue:4

    Topics: Acrolein; Action Potentials; Animals; Ankyrins; Calcium Channels; Camphor; Capsaicin; Evoked Potentials; Hair Follicle; In Vitro Techniques; Isothiocyanates; Male; Mechanoreceptors; Menthol; Physical Stimulation; Pyrimidinones; Rats; Rats, Wistar; Ruthenium Red; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels

2009
TRPA1 receptor induced relaxation of the human urethra involves TRPV1 and cannabinoid receptor mediated signals, and cyclooxygenase activation.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Acrolein; Analysis of Variance; Arginine; Calcium Channels; Capsaicin; Cyclohexanols; Female; Humans; Immunohistochemistry; Indomethacin; Isothiocyanates; Male; Middle Aged; Nerve Tissue Proteins; Receptors, Cannabinoid; Signal Transduction; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Urethra

2010
TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord.
    The European journal of neuroscience, 2010, Volume: 31, Issue:11

    Topics: Acrolein; Action Potentials; Animals; Ankyrins; Antimutagenic Agents; Calcium Channels; Capsaicin; Cell Shape; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Food Preservatives; Inhibitory Postsynaptic Potentials; Isothiocyanates; Male; Nerve Fibers, Unmyelinated; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sensory System Agents; Spinal Cord; Substantia Gelatinosa; Synapses; Synaptic Transmission; TRPA1 Cation Channel; TRPC Cation Channels

2010
Chemo-nociceptive signalling from the colon is enhanced by mild colitis and blocked by inhibition of transient receptor potential ankyrin 1 channels.
    British journal of pharmacology, 2010, Volume: 160, Issue:6

    Topics: Acetanilides; Animals; Capsaicin; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Regulation; Isothiocyanates; Mice; Morphine; Neurons, Afferent; Proto-Oncogene Proteins c-fos; Purines; Signal Transduction; Transient Receptor Potential Channels; TRPA1 Cation Channel

2010
Menthol response and adaptation in nociceptive-like and nonnociceptive-like neurons: role of protein kinases.
    Molecular pain, 2010, Aug-20, Volume: 6

    Topics: Adaptation, Physiological; Animals; Calcium; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Female; Ganglia, Spinal; Isothiocyanates; Male; Menthol; Neurons; Nociceptors; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley

2010
Activation of transient receptor potential A1 by a non-pungent capsaicin-like compound, capsiate.
    British journal of pharmacology, 2012, Volume: 165, Issue:5

    Topics: Animals; Binding Sites; Calcium; Capsaicin; Capsicum; Cells, Cultured; Cytosol; Ganglia, Spinal; HEK293 Cells; Humans; Isothiocyanates; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Zinc

2012
Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice.
    Molecular pain, 2012, Jul-28, Volume: 8

    Topics: Animals; Behavior, Animal; Calcium Channels; Capsaicin; Cisplatin; Cryopyrin-Associated Periodic Syndromes; Ganglia, Spinal; Hyperalgesia; Isothiocyanates; Male; Menthol; Mice; Mice, Inbred C57BL; Nociception; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Transient Receptor Potential Channels; TRPA1 Cation Channel

2012
Epithelial transient receptor potential ankyrin 1 (TRPA1)-dependent adrenomedullin upregulates blood flow in rat small intestine.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Adrenomedullin; Animals; Capsaicin; Isothiocyanates; Jejunum; Male; Panax; Plant Extracts; Rats; Rats, Sprague-Dawley; Regional Blood Flow; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels; Up-Regulation; Vasodilation; Zanthoxylum; Zingiberaceae

2013
Modulation of TRP channels by resveratrol and other stilbenoids.
    Molecular pain, 2013, Feb-15, Volume: 9

    Topics: Animals; Behavior, Animal; Capsaicin; Ganglia, Spinal; HEK293 Cells; Humans; Ion Channel Gating; Isothiocyanates; Male; Mice; Nociception; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transfection; Transient Receptor Potential Channels

2013
Purinoceptor-mediated, capsaicin-resistant excitatory effect of allyl isothiocyanate on neurons of the guinea-pig small intestine.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:2

    Topics: Animals; Atropine; Capsaicin; Cholinergic Agents; Guinea Pigs; Hexamethonium; Intestine, Small; Isothiocyanates; Motor Neurons; Muscle Contraction; Neurons; Pyridoxal Phosphate; Receptors, Purinergic P2; Tetrodotoxin; Transient Receptor Potential Channels; TRPV Cation Channels

2013
Desflurane but not sevoflurane augments laryngeal C-fiber inputs to nucleus tractus solitarii neurons by activating transient receptor potential-A1.
    Life sciences, 2013, May-02, Volume: 92, Issue:14-16

    Topics: Acetanilides; Anesthetics, Inhalation; Animals; Capsaicin; Desflurane; Guinea Pigs; Isoflurane; Isothiocyanates; Laryngeal Nerves; Larynx; Male; Methyl Ethers; Nerve Fibers; Neurons; Purines; Pyrazines; Pyridines; Sevoflurane; Solitary Nucleus; Time Factors; Transient Receptor Potential Channels

2013
Mechanisms of transient receptor potential vanilloid 1 activation and sensitization by allyl isothiocyanate.
    Molecular pharmacology, 2013, Volume: 84, Issue:3

    Topics: Animals; Binding Sites; Capsaicin; Cell Membrane; Cells, Cultured; Ganglia, Spinal; Humans; Hydrogen-Ion Concentration; Isothiocyanates; Mice; Mice, Inbred C57BL; Mutation; Patch-Clamp Techniques; Sensory Receptor Cells; TRPV Cation Channels

2013
Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Animals; Capsaicin; Gastrointestinal Transit; Intestines; Isothiocyanates; Macrophages; Male; Mast Cells; Nociception; Peritoneum; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels

2013
Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity.
    Nature communications, 2013, Volume: 4

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Behavior, Animal; Boron Compounds; Capsaicin; Cell Membrane; Cloning, Molecular; Ganglia, Spinal; HEK293 Cells; Humans; Immunohistochemistry; Ion Channel Gating; Isothiocyanates; Mice; Models, Animal; Molecular Sequence Data; Protein Binding; Rats; RNA, Messenger; Transient Receptor Potential Channels; TRPA1 Cation Channel

2013
Activation of transient receptor potential ankyrin 1 by eugenol.
    Neuroscience, 2014, Mar-07, Volume: 261

    Topics: Acetanilides; Analgesics; Animals; Calcium; Calcium Channels; Capsaicin; Eugenol; HEK293 Cells; Humans; Isothiocyanates; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Purines; Rats; Rats, Sprague-Dawley; Sensory System Agents; Transient Receptor Potential Channels; Trigeminal Ganglion; TRPA1 Cation Channel; TRPC Cation Channels

2014
TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release.
    Journal of dental research, 2014, Volume: 93, Issue:9

    Topics: Acetanilides; Acrolein; Adenosine Triphosphate; Calcium Channels; Calcium Signaling; Capsaicin; Cell Culture Techniques; Cell Line; Culture Media, Conditioned; Dental Pulp; Humans; Isothiocyanates; Leucine; Nerve Tissue Proteins; Nociceptors; Odontoblasts; Purines; Pyrimidinones; Sensory System Agents; Sulfonamides; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2014
A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferents.
    Journal of applied physiology (Bethesda, Md. : 1985), 2015, Feb-01, Volume: 118, Issue:3

    Topics: Animals; Capsaicin; Isothiocyanates; Lung; Mice; Mice, Inbred C57BL; Nerve Fibers, Unmyelinated; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Transient Receptor Potential Channels; TRPV Cation Channels; Vagus Nerve

2015
Novel methods of applying direct chemical and mechanical stimulation to the oral mucosa for traditional behavioral pain assays in conscious rats.
    Journal of neuroscience methods, 2015, Jan-15, Volume: 239

    Topics: Animals; Capsaicin; Consciousness; Grooming; Hyperalgesia; Isothiocyanates; Male; Mouth Mucosa; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Skin; Stimulation, Chemical; Time Factors

2015
Analgesic effects of botulinum neurotoxin type A in a model of allyl isothiocyanate- and capsaicin-induced pain in mice.
    Toxicon : official journal of the International Society on Toxinology, 2015, Volume: 94

    Topics: Analgesics; Animals; Botulinum Toxins, Type A; Capsaicin; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Pain

2015
Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity.
    Anesthesia and analgesia, 2015, Volume: 120, Issue:4

    Topics: Analgesics, Opioid; Calcium; Calcium Channels; Capsaicin; Electrophysiological Phenomena; HEK293 Cells; Humans; Inflammation; Isothiocyanates; Membrane Potentials; Nerve Tissue Proteins; Patch-Clamp Techniques; Receptors, Opioid, mu; Tramadol; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2015
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
    Journal of Zhejiang University. Science. B, 2015, Volume: 16, Issue:3

    Topics: Acetanilides; Analgesics; Animals; Benzamides; Capsaicin; Cold Temperature; Disease Models, Animal; Formaldehyde; Hyperalgesia; Isothiocyanates; Male; Mice; Neuralgia; Oximes; Paclitaxel; Pain Measurement; Purines; Thiophenes; Touch; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2015
Intracolonic Administration of the TRPA1 Agonist Allyl Isothiocyanate Stimulates Colonic Motility and Defecation in Conscious Dogs.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2015, Volume: 19, Issue:7

    Topics: Acetanilides; Anastomosis, Surgical; Animals; Atropine; Capsaicin; Colon; Defecation; Denervation; Dogs; Enteric Nervous System; Ganglionic Blockers; Gastrointestinal Motility; Hexamethonium; Ileum; Isothiocyanates; Muscarinic Antagonists; Ondansetron; Purines; Serotonin Antagonists; Transient Receptor Potential Channels

2015
Enhanced cough reflex in a model of bleomycin-induced lung fibrosis in guinea pigs.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:12

    Topics: Animals; Bleomycin; Brain-Derived Neurotrophic Factor; Bronchoalveolar Lavage Fluid; Capsaicin; Citric Acid; Cough; Cytokines; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Guinea Pigs; Ion Channels; Isothiocyanates; Lung; Male; Matrix Metalloproteinase 2; Pulmonary Fibrosis; Reflex, Abnormal; Time Factors

2015
Characterization of cardiovascular reflexes evoked by airway stimulation with allylisothiocyanate, capsaicin, and ATP in Sprague-Dawley rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Mar-15, Volume: 120, Issue:6

    Topics: Adenosine Triphosphate; Air Pollutants; Animals; Autonomic Nervous System; Bradycardia; Capsaicin; Cardiovascular System; Isothiocyanates; Male; Nerve Fibers, Unmyelinated; Rats; Rats, Sprague-Dawley; Reflex; Respiratory System; Sensory Receptor Cells; TRPC Cation Channels

2016
The TRPA1 Activator Allyl Isothiocyanate (AITC) Contracts Human Jejunal Muscle: Pharmacological Analysis.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:3

    Topics: Acetanilides; Atropine; Calcium Channels; Capsaicin; Cholinergic Agents; Humans; In Vitro Techniques; Isothiocyanates; Jejunum; Muscle Contraction; Nerve Tissue Proteins; Purines; Receptors, Purinergic; Scopolamine; Tetrodotoxin; Transient Receptor Potential Channels; TRPA1 Cation Channel

2016
Transient receptor potential a1 (TRPA1) agonists inhibit contractions of the isolated human ureter.
    Neurourology and urodynamics, 2018, Volume: 37, Issue:2

    Topics: Acrolein; Aged; Calcitonin Gene-Related Peptide; Capsaicin; Female; Humans; Hydrogen Sulfide; Isothiocyanates; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Synaptic Transmission; TRPA1 Cation Channel; TRPV Cation Channels; Tyrosine 3-Monooxygenase; Ureter; Vimentin

2018
Effect of Capsaicin and Other Thermo-TRP Agonists on Thermoregulatory Processes in the American Cockroach.
    Molecules (Basel, Switzerland), 2018, Dec-18, Volume: 23, Issue:12

    Topics: Animals; Capsaicin; Cockroaches; Isothiocyanates; Menthol; Temperature; Thymol; TRPV Cation Channels

2018
Rapid molecular evolution of pain insensitivity in multiple African rodents.
    Science (New York, N.Y.), 2019, 05-31, Volume: 364, Issue:6443

    Topics: Animals; Binding Sites; Capsaicin; Evolution, Molecular; Hydrochloric Acid; Insect Bites and Stings; Isothiocyanates; Mole Rats; NAV1.7 Voltage-Gated Sodium Channel; Nociceptive Pain; Nociceptors; Pain Threshold; Protein Conformation; Sequence Analysis, RNA; Species Specificity; TRPA1 Cation Channel

2019
Enhancement of allyl isothiocyanate-evoked responses of mouse trigeminal ganglion cells by the kokumi substance γ-glutamyl-valyl-glycine (γ-EVG) through activation of the calcium-sensing receptor (CaSR).
    Physiology & behavior, 2023, 03-01, Volume: 260

    Topics: Animals; Capsaicin; Glutathione; Mice; Receptors, Calcium-Sensing; Trigeminal Ganglion; TRPA1 Cation Channel

2023
Allyl isothiocyanate, an activator of TRPA1, increases gastric mucosal blood flow through calcitonin gene-related peptide and adrenomedullin in anesthetized rats.
    Journal of pharmacological sciences, 2023, Volume: 151, Issue:4

    Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Isothiocyanates; Rats; Transient Receptor Potential Channels; TRPA1 Cation Channel

2023
Regional characterisation of TRPV1 and TRPA1 signalling in the mouse colon mucosa.
    European journal of pharmacology, 2023, Sep-05, Volume: 954

    Topics: Animals; Capsaicin; Colon; Mice; Mucous Membrane; Tetrodotoxin; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2023