capsaicin and adenosine

capsaicin has been researched along with adenosine in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.88)18.7374
1990's28 (41.18)18.2507
2000's28 (41.18)29.6817
2010's8 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Del Bianco, E; Maggi, CA; Santicioli, P; Tramontana, M1
Karlsson, JA; Kröll, F; Lundberg, JM; Persson, CG2
Burnstock, G; Hoyle, CH; Ralevic, V1
Nance, D; Reid, A; Sawynok, J1
Sawynok, J; Sweeney, MI; White, TD3
Ballati, L; Manzini, S1
Arwestrom, E; Fasmer, OB; Hunskaar, S; Post, C1
Gustafsson, LE; Wiklund, NP1
Sawynok, J; Sweeney, M; White, T1
Bowie, D; Feltz, P; Schlichter, R1
Kawaguchi, M; Maehara, K; Maruyama, Y; Saito, T; Sato, E; Yaoita, H1
Burnstock, G; Karoon, P; Ralevic, V1
Cahill, CM; Sawynok, J; White, TD2
Fujii, W; Namba, T; Suga, H; Takaki, M1
Chen, IJ; Wu, SN; Yang, JM1
Fujii, T; Imazumi, K; Matsuda, A; Mizuhara, H; Morimoto, H; Ochi, T; Seki, N; Senoh, H; Yamashita, M1
Collins, P; Jiang, C1
Burnstock, G; Ralevic, V; Rubino, A1
Amerini, S; Ledda, F; Mantelli, L; Rubino, A1
Gold, MS; Levine, JD; Reichling, DB; Shuster, MJ1
Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA1
Breschi, MC; Lazzeri, N; Martinotti, L; Nieri, P1
Hurt, CM; Katchanov, G; Pelleg, A; Xu, J1
Hong, JL; Kwong, K; Lee, LY; Morton, RF1
Ho, CY; Hong, JL; Kwong, K; Lee, LY1
Nagai, A; Takeda, Y; Tamaoki, J; Yamawaki, I1
Chapman, ID; Chilvers, ER; Handley, DA; Morley, J; Templeton, AG1
Gebhart, GF; Su, X; Wachtel, RE1
Liu, XJ; Reid, A; Sawynok, J1
Hazato, T; Inoue, M; Matsunaga, S; Ueda, H; Yamamoto, Y1
Arnold, MA; Patterson, SL; Sluka, KA1
Fozard, JR; Hannon, JP; Mazzoni, L; Tigani, B; Williams, I1
Gitlin, JM; Mitchell, JA; Stanford, SJ1
Antunes, E; Brain, SD; Camargo, EA; Costa, SK; de Nucci, G; Esquisatto, LC; Ribela, MT1
Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Ptak, A; Sliwowski, Z1
Curry, R; Eisenach, JC; Hood, DD2
Liu, XJ; Sawynok, J; White, TD2
Gu, Q; Lee, LY1
Burki, N; Gu, Q; Hong, JL; Lee, LY; Ruan, T1
Iwata, F; Leung, FW; Leung, JW; Seno, K1
Boyle, DL; Firestein, GS; Moore, J; Sorkin, LS; Yang, L1
Premkumar, LS; Puntambekar, P; Raisinghani, M; Ramkumar, V; Van Buren, J1
Liu, XJ; Parkinson, FE; Reid, AR; Sawynok, J1
Breen, LT; Mutafova-Yambolieva, VN; Smyth, LM; Yamboliev, IA1
Arulmani, U; Centurión, D; Garrelds, IM; Heiligers, JP; Saxena, PR; Villalón, CM1
Eisenach, JC; Li, X1
Boswell-Smith, V; Keir, S; Page, C; Spina, D1
Chuaychoo, B; Kollarik, M; Lee, MG; Pullmann, R; Undem, BJ1
Benko, I; Brugós, L; Cseppento, A; Deák, G; Edes, I; Galajda, Z; Gesztelyi, R; Kovács, P; Roszer, T; Sipka, S; Szentmiklósi, AJ; Szilasi, M; Zsuga, J1
Docherty, R; Page, CP; Reynolds, SM; Robbins, J; Spina, D1
Kuo, YL; Lai, CJ1
Bien, MY; Ho, CY; Kou, YR; Lin, RL; Lin, YS1
Antunes, C; Böhmer, AE; Elisabetsky, E; Lara, DR; Porciúncula, LO; Schallenberger, C; Schmidt, AP; Souza, DO1
Bien, MY; Hsu, CC; Huang, YT; Kou, YR; Lin, YS; Ruan, T1
Chen, WW; Fan, ZD; Gao, XY; Han, Y; Xiong, XQ; Xu, B; Zhu, GQ1
Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Page, CP; Rendina, EA; Spina, D1
Canning, BJ; Carr, MJ; Chou, YL; Muroi, Y; Ru, F; Undem, BJ1
Lee, LY; Lin, Y; Xu, F; Zang, N; Zhao, L; Zhuang, J1
Li, J; Xing, J1

Trials

2 trial(s) available for capsaicin and adenosine

ArticleYear
Preliminary efficacy assessment of intrathecal injection of an American formulation of adenosine in humans.
    Anesthesiology, 2002, Volume: 96, Issue:1

    Topics: Adenosine; Adult; Analgesics; Capsaicin; Double-Blind Method; Female; Humans; Hyperalgesia; Injections, Spinal; Male; Middle Aged; Pain; Pain Threshold

2002
Dose response of intrathecal adenosine in experimental pain and allodynia.
    Anesthesiology, 2002, Volume: 97, Issue:4

    Topics: Adenosine; Administration, Topical; Adult; Aminophylline; Analgesics, Non-Narcotic; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Hot Temperature; Humans; Hyperalgesia; Hypersensitivity; Infusions, Intravenous; Injections, Spinal; Male; Middle Aged; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists

2002

Other Studies

66 other study(ies) available for capsaicin and adenosine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Adenosine inhibits action potential-dependent release of calcitonin gene-related peptide- and substance P-like immunoreactivities from primary afferents in rat spinal cord.
    Neuroscience letters, 1992, Sep-14, Volume: 144, Issue:1-2

    Topics: Action Potentials; Adenosine; Animals; Baclofen; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Wistar; Spinal Cord; Substance P; Tetrodotoxin

1992
Capsaicin-induced bronchoconstriction and neuropeptide release in guinea pig perfused lungs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:4

    Topics: Acetylcholine; Adenosine; Airway Resistance; Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Interactions; Glycopeptides; Guinea Pigs; Hydrogen-Ion Concentration; Lung; Lung Compliance; Male; Neurokinin A; Neuropeptides; Substance P; Tetrodotoxin

1990
Effects of long-term laxative treatment on rat mesenteric resistance vessel responses in vitro.
    Gastroenterology, 1990, Volume: 99, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Anthraquinones; Calcitonin Gene-Related Peptide; Capsaicin; Cathartics; Electric Stimulation; Female; Mesenteric Arteries; Rats; Rats, Inbred Strains; Senna Extract; Splanchnic Circulation; Substance P; Time Factors; Vasoconstriction

1990
Spinal antinociception by adenosine analogs and morphine after intrathecal administration of the neurotoxins capsaicin, 6-hydroxydopamine and 5,7-dihydroxytryptamine.
    The Journal of pharmacology and experimental therapeutics, 1991, Jul-01, Volume: 258, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Adenosine; Analgesia, Epidural; Analgesics; Animals; Capsaicin; Drug Administration Schedule; Drug Interactions; Hydroxydopamines; Injections, Spinal; Male; Morphine; Oxidopamine; Pain Measurement; Rats; Rats, Inbred Strains; Spinal Cord

1991
5-Hydroxytryptamine releases adenosine and cyclic AMP from primary afferent nerve terminals in the spinal cord in vivo.
    Brain research, 1990, Sep-24, Volume: 528, Issue:1

    Topics: Adenosine; Afferent Pathways; Animals; Capsaicin; Chromatography, High Pressure Liquid; Cyclic AMP; Injections, Spinal; Male; Nerve Endings; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord

1990
Albumin protects against capsaicin- and adenosine-induced bronchoconstriction and reduces overflow of calcitonin gene-related peptide from guinea-pig lung.
    Acta physiologica Scandinavica, 1990, Volume: 139, Issue:1

    Topics: Adenosine; Airway Resistance; Animals; Bronchial Spasm; Calcitonin Gene-Related Peptide; Capsaicin; Guinea Pigs; Immunologic Techniques; Lung; Lung Compliance; Male; Organ Size; Perfusion; Serum Albumin

1990
2-Chloroadenosine induction of vagally-mediated and atropine-resistant bronchomotor responses in anaesthetized guinea-pigs.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anesthesia; Animals; Atropine; Bronchi; Capsaicin; Drug Resistance; Guinea Pigs; Inosine; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Phenylisopropyladenosine; Receptors, Purinergic; Serotonin; Vagus Nerve

1990
Intrathecal injection of capsaicin can be used as a behavioural nociceptive test in mice.
    Neuropharmacology, 1986, Volume: 25, Issue:10

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Capsaicin; Injections, Spinal; Kainic Acid; Male; Mice; Pain Measurement; Receptors, Purinergic; Substance P

1986
Morphine, capsaicin and K+ release purines from capsaicin-sensitive primary afferent nerve terminals in the spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: Adenosine; Animals; Capsaicin; Hydroxydopamines; In Vitro Techniques; Male; Morphine; Neurons, Afferent; Norepinephrine; Oxidopamine; Potassium; Rats; Rats, Inbred Strains; Spinal Cord; Synaptosomes

1989
Adenosine-modulation of cholinergic and non-adrenergic non-cholinergic neurotransmission in the rabbit iris sphincter.
    British journal of pharmacology, 1986, Volume: 88, Issue:1

    Topics: Adenosine; Animals; Atropine; Autonomic Nervous System; Capsaicin; Electric Stimulation; Female; Iris; Isometric Contraction; Male; Muscle Contraction; Muscle Denervation; Parasympathetic Nervous System; Rabbits; Synaptic Transmission

1986
5-Hydroxytryptamine releases adenosine from primary afferent nerve terminals in the spinal cord.
    Brain research, 1988, Oct-18, Volume: 462, Issue:2

    Topics: Adenosine; Animals; Capsaicin; Male; Methysergide; Neurons, Afferent; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Subcellular Fractions; Synaptosomes

1988
Subpopulations of neonatal rat sensory neurons express functional neurotransmitter receptors which elevate intracellular calcium.
    Neuroscience, 1994, Volume: 58, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Bradykinin; Calcium; Capsaicin; Cell Size; Classification; Ganglia, Spinal; Intracellular Fluid; Neurons, Afferent; Rats; Receptors, Neurotransmitter; Substance P

1994
Nonadrenergic noncholinergic nerves regulate basal coronary flow via release of capsaicin-sensitive neuropeptides in the rat heart.
    Circulation research, 1994, Volume: 75, Issue:4

    Topics: Adenosine; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Circulation; Coronary Vessels; Dipeptides; Heart; Hemodynamics; Immunohistochemistry; In Vitro Techniques; Indoles; Male; Myocardium; Neuropeptides; Oxygen Consumption; Rats; Substance P; Ventricular Function, Left

1994
Long-term sensory denervation by neonatal capsaicin treatment augments sympathetic neurotransmission in rat mesenteric arteries by increasing levels of norepinephrine and selectively enhancing postjunctional actions.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Capsaicin; Denervation; In Vitro Techniques; Male; Mesenteric Arteries; Neurons, Afferent; Neuropeptide Y; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Serotonin; Sympathetic Nervous System; Synaptic Transmission; Vasopressins

1995
Involvement of calcium channels in depolarization-evoked release of adenosine from spinal cord synaptosomes.
    Journal of neurochemistry, 1993, Volume: 60, Issue:3

    Topics: Adenosine; Animals; Calcium Channel Blockers; Calcium Channels; Capsaicin; Dihydropyridines; Electrophysiology; omega-Conotoxins; Peptides, Cyclic; Potassium; Ruthenium Red; Spinal Cord; Synaptosomes

1993
Adenosine inhibits efferent function of extrinsic capsaicin-sensitive sensory nerves in the enteric nervous system.
    European journal of pharmacology, 1993, Jun-11, Volume: 237, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Capsaicin; Electric Stimulation; Electrophysiology; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mesentery; Muscle Contraction; Myenteric Plexus; Nerve Fibers; Neurons, Afferent; Neurons, Efferent; Substance P; Theophylline

1993
Spinal adenosine modulates capsaicin-induced depressor reflex: involvement of adenosine A2 receptor.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Adenosine; Animals; Blood Pressure; Capsaicin; Hemodynamics; Injections, Spinal; Male; Nerve Fibers; Neurons, Afferent; Peptide Fragments; Rats; Rats, Wistar; Receptors, Purinergic P1; Reflex; Spinal Cord; Substance P; Theophylline

1993
Effects of adenosine A2 receptor agonists on the excitation of capsaicin-sensitive afferent sensory nerves in airway tissues.
    European journal of pharmacology, 1993, Aug-24, Volume: 240, Issue:2-3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Bronchi; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neurons, Afferent; Nicotiana; Phenethylamines; Plants, Toxic; Rats; Rats, Wistar; Receptors, Purinergic P1; Smoke; Substance P; Trachea

1993
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Rabbits; Tetrodotoxin; Theophylline

1994
The P1-purinoceptors that mediate the prejunctional inhibitory effect of adenosine on capsaicin-sensitive nonadrenergic noncholinergic neurotransmission in the rat mesenteric arterial bed are of the A1 subtype.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Adenosine; Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cholinergic Fibers; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Tonus; Muscle, Smooth, Vascular; Neuromuscular Junction; Rats; Rats, Wistar; Receptors, Purinergic P1; Sensitivity and Specificity; Synaptic Transmission; Theophylline; Vasodilation; Xanthines

1993
Pertussis toxin does not affect the adenosine-induced inhibition of the efferent function of cardiac capsaicin-sensitive nerves.
    Journal of neural transmission. General section, 1993, Volume: 92, Issue:1

    Topics: Adenosine; Animals; Autonomic Nervous System; Capsaicin; Electric Stimulation; GTP-Binding Proteins; Guinea Pigs; Heart; Male; Neurons, Efferent; Pertussis Toxin; Virulence Factors, Bordetella

1993
Influence of calcium on the release of endogenous adenosine from spinal cord synaptosomes.
    Life sciences, 1993, Volume: 53, Issue:6

    Topics: Adenosine; Analysis of Variance; Animals; Calcimycin; Calcium; Capsaicin; Dose-Response Relationship, Drug; Egtazic Acid; Ethanol; Injections, Spinal; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptosomes

1993
Morphine-evoked release of adenosine from the spinal cord occurs via a nucleoside carrier with differential sensitivity to dipyridamole and nitrobenzylthioinosine.
    Brain research, 1993, Jun-18, Volume: 614, Issue:1-2

    Topics: Adenosine; Animals; Capsaicin; Dipyridamole; In Vitro Techniques; Male; Morphine; Norepinephrine; Nucleosides; Potassium; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Synaptosomes; Thioinosine

1993
Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-06, Volume: 93, Issue:3

    Topics: Adenosine; Animals; Capsaicin; Cells, Cultured; Dinoprostone; Ganglia, Spinal; Hyperalgesia; Kinetics; Male; Membrane Potentials; Neurons; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Serotonin; Sodium Channels; Tetrodotoxin; Thromboxane B2

1996
Genetic control of indirect airway responsiveness in the rat.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25 Suppl 2

    Topics: Adenosine; Animals; Atropine; Blood Proteins; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Capillary Permeability; Capsaicin; Male; Methysergide; Nedocromil; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Respiratory Function Tests; Serotonin; Serotonin Antagonists; Specific Pathogen-Free Organisms; Substance P; Tachykinins

1995
Effects of adenosine on NANC bronchoconstriction in anaesthetized guinea-pigs.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:4

    Topics: Action Potentials; Adenosine; Airway Resistance; Anesthesia, Intravenous; Animals; Autonomic Nervous System; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Substance P; Vagus Nerve

1996
Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. III. Role of cardiac afferents.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 2

    Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Capsaicin; Denervation; Dogs; Electrophysiology; Female; Heart Atria; Heart Conduction System; Injections; Lung; Male; Neurons, Afferent; Reflex; Sinoatrial Node; Vagotomy; Vagus Nerve

1996
Role of pulmonary C fibers in adenosine-induced respiratory inhibition in anesthetized rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:2

    Topics: Adenosine; Anesthesia; Animals; Capsaicin; Chemoreceptor Cells; Heart Ventricles; Injections; Lung; Male; Nerve Fibers; Pulmonary Ventilation; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reflex; Respiration; Vagus Nerve; Xanthines

1998
Activation of pulmonary C fibres by adenosine in anaesthetized rats: role of adenosine A1 receptors.
    The Journal of physiology, 1998, Apr-01, Volume: 508 ( Pt 1)

    Topics: Action Potentials; Adenosine; Afferent Pathways; Anesthesia, General; Animals; Capsaicin; Inosine; Lung; Male; Nerve Fibers; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Purinergic P1; Respiration; Theobromine; Time Factors; Trachea; Vagus Nerve; Xanthines

1998
[Effect of adenosine and its analogues on microvascular leakage in the rat trachea].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 1998, Volume: 36, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Male; Neurons, Afferent; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substance P; Tachykinins; Trachea; Vasodilator Agents

1998
Effects of S-salbutamol on human isolated bronchus.
    Pulmonary pharmacology & therapeutics, 1998, Volume: 11, Issue:1

    Topics: Adenosine; Albuterol; Bradykinin; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene C4; Methacholine Chloride; Platelet Activating Factor

1998
Capsaicin sensitivity and voltage-gated sodium currents in colon sensory neurons from rat dorsal root ganglia.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Action Potentials; Adenosine; Analgesics; Animals; Bradykinin; Capsaicin; Carbocyanines; Colon; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Fluorescent Dyes; Ganglia, Spinal; Histamine; Ion Channel Gating; Male; Neurons, Afferent; Pain; Rats; Rats, Sprague-Dawley; Serotonin; Sodium; Sodium Channels; Tetrodotoxin

1999
Involvement of mast cells, sensory afferents and sympathetic mechanisms in paw oedema induced by adenosine A(1) and A(2B/3) receptor agonists.
    European journal of pharmacology, 2000, Apr-21, Volume: 395, Issue:1

    Topics: Adenosine; Animals; Capsaicin; Dose-Response Relationship, Drug; Edema; Hindlimb; Male; Mast Cells; Neurons, Afferent; Oxidopamine; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptor, Adenosine A3; Sympathetic Nervous System; Sympatholytics

2000
Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine.
    Peptides, 2000, Volume: 21, Issue:8

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Analgesics, Opioid; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mice; Morphine; Neurons, Afferent; Neuroprotective Agents; Oligopeptides; Pain; Pertussis Toxin; Piperidines; Protease Inhibitors; Purinergic Agonists; Thionucleosides; Time Factors; Virulence Factors, Bordetella

2000
A novel transverse push-pull microprobe: in vitro characterization and in vivo demonstration of the enzymatic production of adenosine in the spinal cord dorsal horn.
    Journal of neurochemistry, 2001, Volume: 76, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Male; Microdialysis; Nitrophenols; Physical Stimulation; Posterior Horn Cells; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Spinal Cord; Theophylline

2001
Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Adenosine; Allergens; Animals; Atropine; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Capsaicin; Cardiovascular System; Cell Degranulation; Cromolyn Sodium; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Ketanserin; Lung; Male; Mast Cells; Methacholine Chloride; Methysergide; Ovalbumin; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred BN; Respiratory Hypersensitivity; Serotonin; Serotonin Antagonists; Time Factors; Vagotomy; Vasoconstrictor Agents

2001
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
    British journal of pharmacology, 2001, Volume: 133, Issue:6

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation

2001
The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Proteins; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Female; Injections, Intradermal; Isotonic Solutions; Male; Mast Cells; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Piperidines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Skin; Substance P; Theobromine

2001
Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves.
    European journal of pharmacology, 2001, Sep-21, Volume: 427, Issue:3

    Topics: Adenosine; Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Digestive System; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Sulfones; Theophylline; Time Factors

2001
Intraplantar injection of glutamate evokes peripheral adenosine release in the rat hind paw: involvement of peripheral ionotropic glutamate receptors and capsaicin-sensitive sensory afferents.
    Journal of neurochemistry, 2002, Volume: 80, Issue:4

    Topics: Adenosine; Animals; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feedback, Physiological; Formaldehyde; Glutamic Acid; Hindlimb; Injections, Subcutaneous; Male; Microdialysis; Neurons, Afferent; Oxidopamine; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Skin

2002
Alveolar hypercapnia augments pulmonary C-fiber responses to chemical stimulants: role of hydrogen ion.
    Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:1

    Topics: Adenosine; Animals; Bicarbonates; Biguanides; Blood Pressure; Capsaicin; Extracellular Space; Hydrogen; Hydrogen-Ion Concentration; Hypercapnia; Lung; Male; Nerve Fibers, Unmyelinated; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Stimulation, Chemical

2002
Enhanced release of adenosine in rat hind paw following spinal nerve ligation: involvement of capsaicin-sensitive sensory afferents.
    Neuroscience, 2002, Volume: 114, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Afferent Pathways; Animals; Capsaicin; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Male; Nerve Crush; Nerve Fibers, Unmyelinated; Neuralgia; Neurons, Afferent; Nociceptors; Oxidopamine; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Skin; Spinal Nerves; Sympathetic Fibers, Postganglionic

2002
Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:3

    Topics: Adenosine; Anesthesia; Animals; Body Weight; Bradycardia; Bronchial Hyperreactivity; Capsaicin; Dose-Response Relationship, Drug; Infusions, Intravenous; Lung; Male; Nerve Fibers, Unmyelinated; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P1; Xanthines

2003
Acid-induced mesenteric hyperemia in rats: role of CGRP, substance P, prostaglandin, adenosine, and histamine.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:3

    Topics: Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Hydrochloric Acid; Hyperemia; Intestinal Mucosa; Laser-Doppler Flowmetry; Male; Mesenteric Artery, Superior; Mesentery; Nerve Tissue Proteins; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Regional Blood Flow; Substance P; Vasodilator Agents

2003
Regulation of peripheral inflammation by spinal adenosine: role of somatic afferent fibers.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: Adenosine; Animals; Capsaicin; Feedback; Inflammation; Injections, Spinal; Male; Nerve Fibers; Neurons, Afferent; Neuropeptides; Neutrophil Infiltration; Neutrophils; Oxidopamine; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Nerve Roots; Sympathectomy, Chemical; Sympatholytics

2003
Direct interaction of adenosine with the TRPV1 channel protein.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Apr-07, Volume: 24, Issue:14

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Binding, Competitive; Capsaicin; Cell Membrane; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Ganglia, Spinal; Humans; Kidney; Neurons; Oocytes; Phenethylamines; Protein Binding; Rats; Receptors, Drug; Xenopus laevis

2004
Amitriptyline enhances extracellular tissue levels of adenosine in the rat hindpaw and inhibits adenosine uptake.
    European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Capsaicin; Cell Line, Tumor; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Extracellular Space; Hindlimb; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Time Factors

2005
beta-NAD is a novel nucleotide released on stimulation of nerve terminals in human urinary bladder detrusor muscle.
    American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:2

    Topics: Adenosine; Adrenergic Agents; Animals; Botulinum Toxins, Type A; Capsaicin; Chromatography, High Pressure Liquid; Conotoxins; Electric Stimulation; Guanethidine; Guanine Nucleotides; Humans; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NAD; omega-Agatoxin IVA; Stereoisomerism; Synaptosomal-Associated Protein 25; Tetrodotoxin; Urinary Bladder

2006
Lack of effect of the adenosine A1 receptor agonist, GR79236, on capsaicin-induced CGRP release in anaesthetized pigs.
    Cephalalgia : an international journal of headache, 2005, Volume: 25, Issue:11

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Blood Flow Velocity; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Carotid Arteries; Female; Heart Rate; Hemodynamics; Infusions, Intra-Arterial; Oxygen; Sus scrofa

2005
Adenosine reduces glutamate release in rat spinal synaptosomes.
    Anesthesiology, 2005, Volume: 103, Issue:5

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Capsaicin; Glutamic Acid; In Vitro Techniques; Ligation; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves; Synaptosomes; TRPV Cation Channels

2005
Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.
    British journal of pharmacology, 2006, Volume: 147, Issue:7

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Airway Obstruction; Airway Resistance; Anesthesia; Animals; Bronchoalveolar Lavage Fluid; Capsaicin; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; Lung; Male; Neural Pathways; Ovalbumin; Pyrilamine; Respiratory Function Tests; Respiratory Hypersensitivity; Vagotomy; Xanthines

2006
Evidence for both adenosine A1 and A2A receptors activating single vagal sensory C-fibres in guinea pig lungs.
    The Journal of physiology, 2006, Sep-01, Volume: 575, Issue:Pt 2

    Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Capsaicin; Gene Expression Regulation; Guinea Pigs; Lung; Male; Nerve Fibers, Unmyelinated; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Phenethylamines; Pyrimidines; Receptor, Adenosine A1; Receptors, Adenosine A2; RNA, Messenger; Triazoles; Xanthines

2006
Modulation of adenosine-induced responses in the guinea-pig trachea during long-term caffeine treatment: possible role of epithelium.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:3

    Topics: Adenosine; Animals; Body Weight; Caffeine; Capsaicin; Cromolyn Sodium; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitroarginine; Trachea

2007
Adenosine induces a cholinergic tracheal reflex contraction in guinea pigs in vivo via an adenosine A1 receptor-dependent mechanism.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Administration, Inhalation; Airway Resistance; Animals; Calcium; Capsaicin; Chlorocebus aethiops; COS Cells; Cough; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Injections, Intravenous; Laryngeal Nerves; Ligation; Male; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Receptor, Adenosine A1; Reflex; Respiratory Function Tests; Trachea; Transfection; TRPV Cation Channels

2008
Ovalbumin sensitizes vagal pulmonary C-fiber afferents in Brown Norway rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:2

    Topics: Adenosine; Airway Resistance; Analgesics; Animals; Biguanides; Blood Pressure; Bronchi; Capsaicin; Electrophysiology; Immunization; Lung; Male; Muscle Contraction; Nerve Fibers, Unmyelinated; Ovalbumin; Rats; Rats, Inbred BN; Reflex; Vagus Nerve

2008
Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:4

    Topics: Adenosine; Animals; Apnea; Arachidonic Acids; Blood Pressure; Capsaicin; Endocannabinoids; Heart Rate; Infusions, Intravenous; Lung; Male; Morpholines; Neurons, Afferent; Physical Stimulation; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; TRPV Cation Channels; Vagus Nerve

2009
Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.
    British journal of pharmacology, 2009, Volume: 156, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Allopurinol; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamic Acid; Hot Temperature; Injections, Intraperitoneal; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrimidines; Triazoles; Uric Acid; Xanthine Oxidase; Xanthines

2009
N-arachidonyl dopamine sensitizes rat capsaicin-sensitive lung vagal afferents via activation of TRPV1 receptors.
    Respiratory physiology & neurobiology, 2009, Jul-31, Volume: 167, Issue:3

    Topics: Adenosine; Animals; Arachidonic Acids; Capsaicin; Dopamine; Hemodynamics; Male; Nerve Fibers; Neurons, Afferent; Physical Stimulation; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Respiration, Artificial; Respiratory Mechanics; TRPV Cation Channels; Vagus Nerve

2009
Responses of neurons in paraventricular nucleus to activation of cardiac afferents and acute myocardial ischaemia in rats.
    Experimental physiology, 2011, Volume: 96, Issue:3

    Topics: Adenosine; Animals; Aortic Coarctation; Blood Pressure; Bradykinin; Capsaicin; Denervation; Heart; Hydrogen Peroxide; Male; Myocardial Ischemia; Neurons; Paraventricular Hypothalamic Nucleus; Pressoreceptors; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vagus Nerve

2011
Pharmacological characterization of adenosine receptors on isolated human bronchi.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:6

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Asthma; Bronchi; Bronchoconstriction; Capsaicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organ Culture Techniques; Receptor, Adenosine A1; Sensory System Agents; Vasodilator Agents

2011
Selective inhibition of vagal afferent nerve pathways regulating cough using Nav 1.7 shRNA silencing in guinea pig nodose ganglia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Jun-01, Volume: 304, Issue:11

    Topics: Adenosine; Adenosine Triphosphate; Afferent Pathways; Anesthesia; Animals; Capsaicin; Consciousness; Cough; Dependovirus; Electrophysiological Phenomena; Gene Silencing; Genetic Vectors; Green Fluorescent Proteins; Guinea Pigs; Male; NAV1.7 Voltage-Gated Sodium Channel; Nerve Fibers, Unmyelinated; Nodose Ganglion; Physical Stimulation; RNA, Small Interfering; Serotonin; Vagus Nerve

2013
Prenatal nicotinic exposure upregulates pulmonary C-fiber NK1R expression to prolong pulmonary C-fiber-mediated apneic response.
    Toxicology and applied pharmacology, 2016, Jan-01, Volume: 290

    Topics: Adenosine; Animals; Animals, Newborn; Apnea; Bronchoalveolar Lavage Fluid; Capsaicin; Female; Ganglia; Lung; Male; Nerve Fibers, Unmyelinated; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; RNA, Messenger; Substance P; TRPV Cation Channels; Up-Regulation; Vagus Nerve

2016
The Role Played by Adenosine in Modulating Reflex Sympathetic and Pressor Responses Evoked by Stimulation of TRPV1 in Muscle Afferents.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 40, Issue:1-2

    Topics: Adenosine; Animals; Blood Pressure; Capsaicin; Fluorescent Antibody Technique; Ganglia, Spinal; Ion Channel Gating; Kidney; Male; Muscle, Skeletal; Neurons, Afferent; Phenethylamines; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System; TRPV Cation Channels

2016