capsaicin and 1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea

capsaicin has been researched along with 1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bianchi, BR; El Kouhen, R; Faltynek, CR; Gomtsyan, A; Jarvis, MF; Lee, CH; McDonald, HA; Moreland, RB; Neelands, TR; Puttfarcken, PS; Raja, SN; Surber, B; Surowy, CS; Vaidyanathan, SN1
El Kouhen, R; Faltynek, CR; Gauvin, DM; Gomtsyan, A; Honore, P; Jarvis, MF; Lee, CH; Marsh, K; Mikusa, J; Sullivan, JP; Wismer, CT; Zhong, C; Zhu, CZ1
Faltynek, CR; Han, P; Jarvis, MF; Neelands, TR; Surowy, CS1
Bradbury, M; Gogas, K; Jaffe, R; McMackin, M; Mills, C; Slee, D; Yu, J; Zininberg, E1
Faltynek, CR; Han, P; Kort, M; McDonald, HA; Moreland, RB; Neelands, TR; Puttfarcken, PS; Vos, MH1
Bautista, DM; Lennertz, RC; Stucky, CL; Tsunozaki, M1
Barabas, ME; Brandow, AM; Hillery, CA; Kerstein, PC; Retherford, D; Stucky, CL; Vilceanu, D; Wandersee, NJ1
Callejo, G; Chakrabarti, S; Hockley, JRF; Pattison, LA; Singhal, K; Smith, ESJ1

Other Studies

8 other study(ies) available for capsaicin and 1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea

ArticleYear
[3H]A-778317 [1-((R)-5-tert-butyl-indan-1-yl)-3-isoquinolin-5-yl-urea]: a novel, stereoselective, high-affinity antagonist is a useful radioligand for the human transient receptor potential vanilloid-1 (TRPV1) receptor.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:1

    Topics: Animals; Binding, Competitive; Calcium Signaling; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Ganglia, Spinal; Humans; Isoquinolines; Ligands; Molecular Structure; Neurons, Afferent; Radioligand Assay; Rats; Recombinant Proteins; Stereoisomerism; Transfection; Tritium; TRPV Cation Channels; Urea

2007
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Acute Disease; Analgesics; Animals; Capsaicin; Carrageenan; Chronic Disease; Dose-Response Relationship, Drug; Edema; Formaldehyde; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Isoquinolines; Ligation; Male; Motor Activity; Osteoarthritis; Pain; Pain Measurement; Pain, Postoperative; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sciatic Nerve; Spinal Nerves; Urea

2005
Acidification of rat TRPV1 alters the kinetics of capsaicin responses.
    Molecular pain, 2005, Sep-28, Volume: 1

    Topics: Acids; Animals; Capsaicin; Cell Line; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Isoquinolines; Kinetics; Protons; Rats; Time Factors; TRPV Cation Channels; Urea

2005
Effects of the transient receptor potential vanilloid 1 antagonist A-425619 on body temperature and thermoregulation in the rat.
    Neuroscience, 2008, Sep-22, Volume: 156, Issue:1

    Topics: Administration, Oral; Animals; Body Temperature; Body Temperature Regulation; Capsaicin; Circadian Rhythm; Drug Administration Schedule; Fever; Hypothalamus; Hypothermia; Isoquinolines; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Time Factors; TRPV Cation Channels; Urea

2008
Characterization of A-425619 at native TRPV1 receptors: a comparison between dorsal root ganglia and trigeminal ganglia.
    European journal of pharmacology, 2008, Oct-31, Volume: 596, Issue:1-3

    Topics: Aminobutyrates; Animals; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Ganglia, Spinal; Isoquinolines; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tissue Culture Techniques; Trigeminal Ganglion; TRPV Cation Channels; Urea

2008
Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Mar-24, Volume: 30, Issue:12

    Topics: Action Potentials; Amides; Animals; Animals, Newborn; Capsaicin; Cells, Cultured; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Mechanoreceptors; Mice; Mice, Inbred C57BL; Mustard Plant; Nerve Fibers; Nerve Growth Factors; Neural Conduction; Neurons, Afferent; Paresthesia; Plant Oils; Sensory Receptor Cells; Sensory System Agents; Skin; Statistics, Nonparametric; Touch; Trigeminal Ganglion; Urea

2010
Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease.
    Blood, 2011, Sep-22, Volume: 118, Issue:12

    Topics: Action Potentials; Anemia, Sickle Cell; Animals; Capsaicin; Disease Models, Animal; Female; Humans; Hyperalgesia; Hypoxia; Isoquinolines; Male; Mice; Mice, Inbred Strains; Microelectrodes; Nociceptors; Pain; Pain Measurement; Patch-Clamp Techniques; TRPV Cation Channels; Urea

2011
Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner.
    Neuropharmacology, 2018, Volume: 143

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Capsaicin; Cells, Cultured; Disease Models, Animal; Female; Freund's Adjuvant; gamma-Aminobutyric Acid; Ganglia, Spinal; Hindlimb; Inflammation; Isoquinolines; Mice, Inbred C57BL; Motor Activity; Receptor, trkA; Sensory Receptor Cells; TRPV Cation Channels; Urea

2018