caprylates has been researched along with vx-770 in 1 studies
| Studies (caprylates) | Trials (caprylates) | Recent Studies (post-2010) (caprylates) | Studies (vx-770) | Trials (vx-770) | Recent Studies (post-2010) (vx-770) |
|---|---|---|---|---|---|
| 5,061 | 100 | 2,339 | 753 | 60 | 731 |
| Protein | Taxonomy | caprylates (IC50) | vx-770 (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.57 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bear, CE; Eckford, PD; Li, C; Ramjeesingh, M | 1 |
1 other study(ies) available for caprylates and vx-770
| Article | Year |
|---|---|
Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner.
Topics: Adenosine Triphosphate; Aminophenols; Animals; Caprylates; Cell Line; Chromatography, Affinity; Cystic Fibrosis Transmembrane Conductance Regulator; Detergents; Fluorocarbons; Humans; Ion Channel Gating; Liposomes; Mutant Proteins; Mutation, Missense; Phosphorylation; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Quinolones; Sequence Deletion; Signal Transduction; Spodoptera | 2012 |