Page last updated: 2024-09-03

caprylates and tacrolimus

caprylates has been researched along with tacrolimus in 2 studies

Compound Research Comparison

Studies
(caprylates)
Trials
(caprylates)
Recent Studies (post-2010)
(caprylates)
Studies
(tacrolimus)
Trials
(tacrolimus)
Recent Studies (post-2010) (tacrolimus)
5,0611002,33917,7572,3196,661

Protein Interaction Comparison

ProteinTaxonomycaprylates (IC50)tacrolimus (IC50)
Bile salt export pumpHomo sapiens (human)7.18
Cytochrome P450 3A4Homo sapiens (human)0.58
Cytochrome P450 3A5Homo sapiens (human)0.385
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0021
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.2547
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)0.0148
Splicing factor 3B subunit 3Homo sapiens (human)0.0123
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.7

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Claes, K; Evenepoel, P; Kuypers, DR; Maes, B; Vanrenterghem, Y1
Gan, Y; Wang, YP; Zhang, XX1

Other Studies

2 other study(ies) available for caprylates and tacrolimus

ArticleYear
The rate of gastric emptying determines the timing but not the extent of oral tacrolimus absorption: simultaneous measurement of drug exposure and gastric emptying by carbon-14-octanoic acid breath test in stable renal allograft recipients.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:12

    Topics: Administration, Oral; Area Under Curve; Breath Tests; Caprylates; Dose-Response Relationship, Drug; Female; Gastric Emptying; Half-Life; Humans; Immunosuppressive Agents; Intestinal Absorption; Kidney Transplantation; Male; Middle Aged; Tacrolimus

2004
Novel gastroretentive sustained-release tablet of tacrolimus based on self-microemulsifying mixture: in vitro evaluation and in vivo bioavailability test.
    Acta pharmacologica Sinica, 2011, Volume: 32, Issue:10

    Topics: Animals; Biological Availability; Caprylates; Delayed-Action Preparations; Dogs; Emulsions; Female; Gastrointestinal Tract; Glycerides; Immunosuppressive Agents; Male; Polyethylene Glycols; Rabbits; Tablets; Tacrolimus

2011